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Photo of  William A. Knight IV, MD

William A. Knight IV, MD

Professor of Clinical

Director, EM MLP Program

Emergency Medicine | College of Medicine

  • Bachelor's Degree: University of Dayton
  • Medical Degree: University of Cincinnati
  • Residency: University of Cincinnati
  • Fellowship: University of Cincinnati
Board Certifications & Licenses

American Board of Emergency Medicine (Certification Date: 20081113) - (Recertification Date: 20190101)
United Council for Neurologic Subspecialties (Certification Date: 20101231)


Emergency Medicine
Neurocritical Care

Research Interests

neurocritical care, neurotrauma, stroke

Contact Information

Clinical Interests

Emergency Medicine

Peer Reviewed Publications

Smith, Matthew S; Bonomo, Jordan; Knight, William A; Prestigiacomo, Charles J; Richards, Christopher T; Ramser, Evan; Adeoye, Opeolu; Bertsch, Stuart; Shirani, Peyman; Vagal, Achala; Fichtenbaum, Carl J; Housholder, Anne; Khatri, Pooja; Kleindorfer, Dawn O; Broderick, Joseph P; Grossman, Aaron W 2020. Endovascular Therapy for Patients With Acute Ischemic Stroke During the COVID-19 Pandemic: A Proposed Algorithm. Stroke, 51 6, 1902-1909

Fuller, Brian M; Roberts, Brian W; Mohr, Nicholas M; Knight, William A; Adeoye, Opeolu; Pappal, Ryan D; Marshall, Stacy; Alunday, Robert; Dettmer, Matthew; Goyal, Munish; Gibson, Colin; Levine, Brian J; Gardner-Gray, Jayna M; Mosier, Jarrod; Dargin, James; Mackay, Fraser; Johnson, Nicholas J; Lokhandwala, Sharukh; Hough, Catherine L; Tonna, Joseph E; Tsolinas, Rachel; Lin, Frederick; Qasim, Zaffer A; Harvey, Carrie E; Bassin, Benjamin; Stephens, Robert J; Yan, Yan; Carpenter, Christopher R; Kollef, Marin H; Avidan, Michael S 2019. The ED-SED Study: A Multicenter, Prospective Cohort Study of Practice Patterns and Clinical Outcomes Associated With Emergency Department SEDation for Mechanically Ventilated Patients. Critical care medicine, 47 11, 1539-1548

Knight, William A; Hart, Kimberly W; Adeoye, Opeolu M; Bonomo, Jordan B; Keegan, Shaun P; Ficker, David M; Szaflarski, Jerzy P; Privitera, Michael D; Lindsell, Christopher J 2013. The incidence of seizures in patients undergoing therapeutic hypothermia after resuscitation from cardiac arrest. Epilepsy research, 106 3, 396-402

Pancioli, Arthur M; Adeoye, Opeolu; Schmit, Pamela A; Khoury, Jane; Levine, Steven R; Tomsick, Thomas A; Sucharew, Heidi; Brooks, Claudette E; Crocco, Todd J; Gutmann, Laurie; Hemmen, Thomas M; Kasner, Scott E; Kleindorfer, Dawn; Knight, William A; Martini, Sharyl; McKinney, James S; Meurer, William J; Meyer, Brett C; Schneider, Alexander; Scott, Phillip A; Starkman, Sidney; Warach, Steven; Broderick, Joseph P 2013. Combined approach to lysis utilizing eptifibatide and recombinant tissue plasminogen activator in acute ischemic stroke-enhanced regimen stroke trial. Stroke, 44 9, 2381-7

Zammit, Christopher; Knight, William A 2013. Severe traumatic brain injury in adults. Emergency medicine practice, 15 3, 1-28

McMullan, Jason T; Hinckley, William; Bentley, Jared; Davis, Todd; Fermann, Gregory J; Gunderman, Matthew; Hart, Kimberly Ward; Knight, William A; Lindsell, Christopher J; Miller, Chris; Shackleford, April; Gibler, W Brian 2012. Ground emergency medical services requests for helicopter transfer of ST-segment elevation myocardial infarction patients decrease medical contact to balloon times in rural and suburban settings. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 19 2, 153-60

McMullan, Jason T; Hinckley, William; Bentley, Jared; Davis, Todd; Fermann, Gregory J; Gunderman, Matthew; Hart, Kimberly Ward; Knight, William A; Lindsell, Christopher J; Shackleford, April; Gibler, W Brian 2011. Reperfusion is delayed beyond guideline recommendations in patients requiring interhospital helicopter transfer for treatment of ST-segment elevation myocardial infarction. Annals of emergency medicine, 57 3, 213-220.e1

McMullan, Jason T; Knight, William A; Clark, Joseph F; Beyette, Fred R; Pancioli, Arthur 2010. Time-critical neurological emergencies: the unfulfilled role for point-of-care testing. International journal of emergency medicine, 3 2, 127-31

Schwamm, Lee H; Holloway, Robert G; Amarenco, Pierre; Audebert, Heinrich J; Bakas, Tamilyn; Chumbler, Neale R; Handschu, Rene; Jauch, Edward C; Knight, William A; Levine, Steven R; Mayberg, Marc; Meyer, Brett C; Meyers, Philip M; Skalabrin, Elaine; Wechsler, Lawrence R 2009. A review of the evidence for the use of telemedicine within stroke systems of care: a scientific statement from the American Heart Association/American Stroke Association. Stroke, 40 7, 2616-34

Knight, W A; Livingston, R B; Gregory, E J; McGuire, W L 1977. Estrogen receptor as an independent prognostic factor for early recurrence in breast cancer. Cancer research, 37 12, 4669-71

Bohanske M.; Knight W.; McMullan J. 12-01-2015. MORNING EMERGENCIES. A guide to wake-up ischemic strokes Morning emergencies JEMS : a journal of emergency medical services, 40 12, 35-38

Palmer C.; McMullan J.; Knight W.; Gunderman M.; Hinckley W. 11-01-2011. Helicopter scene response for a STEMI patient transported directly to the cardiac catheterization la Air Medical Journal, 30 6, 289-292

McMullan J.T.; Jones E.; Barnhart B.; Denninghoff K.; Spaite D.; Zaleski E.; Silbergleit R.; Lowenstein D.; Barsan W.; Pancioli A.; Stevenson V.; Harney D.; Harsh D.; Pinkerton J.; Kade A.; Siewert N.; Pinawin A.; Ring C.; Brenne P.; Vonderschmidt K.; Durkalski V.; Palesch Y.; Dillon C.; Pauls K.; Wu Q.; Zhao W.; Conwit R.; Janis S.; Jett D.; Fureman B.; Welch R.D.; Mango L.; Mika V.H.; Atas J.; Dunne R.; Wheaton D.; Levy P.; Velilla M.A.; Sherwin R.; O'Neil B.; Groves A.; Rosenthal M.; Ewing I.; Waymeyer P.; Kay Vonderschmidt M.; Schwartz H.; Stettler B.; Knight W.; Adeoye O.; Cadena R.; Bonomo J.; Grise E.; Heitsch L.; Shaw G.; Gagai N.; Schmit P.; Stark S.; Doellman T.; Hemphill J.C.; Meeker M.; Rosborough K.; Sporer K.; Gelb A.; Smith W.; Ramanujam P.; Nakagawa K.; Moheet A.; Kamel H.; Naravetla B.; Mercer M.; Wong C.; Milling T.J.; Ottman M.; King B.; LaChance L.; Brockman J.; Didonato P.; Hinchey P.; Wright D.W.; Bitner M.D.; Beltran G.W.; Nevarez H.; Barnhard R.; McDougal A.G.; Linzer J.F.; Merck L.H.; Espinoza T.; Lewandowski C.A.; Vohra T.T.; Crouse P.L.; Baker A.E.; Creech D.R.; Russman A.N.; Miller J.B.; Nagarwala J.; Miller D.J.; Fowkes R.; Lundell A.M.; Quinn J.V.; Casal S. 07-01-2014. Degradation of benzodiazepines after 120 days of EMS deployment Prehospital Emergency Care, 18 3, 368-374

McMullan J.; Knight W.; Clark J.; Beyette F.; Pancioli A. 06-01-2010. Time-critical neurological emergencies: The unfulfilled role for point-of-care testing International Journal of Emergency Medicine, 3 2, 127-131

McMullan J.T.; Hinckley W.; Bentley J.; Davis T.; Fermann G.J.; Gunderman M.; Hart K.W.; Knight W.A.; Lindsell C.J.; Shackleford A.; Gibler W.B. 01-01-2011. Reperfusion is delayed beyond guideline recommendations in patients requiring interhospital helicopt Annals of Emergency Medicine, 57 3,

Adeoye, Opeolu; Knight, William A; Khoury, Jane; Schmit, Pamela A; Sucharew, Heidi; Broderick, Joseph P; Pancioli, Arthur M . A matched comparison of eptifibatide plus rt-PA versus rt-PA alone in acute ischemic stroke. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 23 5, e313-5

Knight, William A; Gunderman, Matthew; Hinckley, William R . Critical burn patient with an unknown neuromuscular disease: conclusion. Air medical journal, 27 4, 160-6

Knight, William A; Gunderman, Matthew; Hinckley, William R . Critical burn patient with an unknown neuromuscular disease. Air medical journal, 27 3, 114-5

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Department of
Emergency Medicine

Medical Sciences Building Room 1654
231 Albert Sabin Way
PO Box 670769
Cincinnati, OH 45267-0769

Mail Location: 0769
Phone: 513-558-5281