Today is Saturday, May. 26, 2018

Department of Environmental Health

Center for Environmental Genetics

Center for Environmental Genetics

2018 April: UC Awarded $8 Million to Continue 'Gene-Environment Interactions' Research

Funded by the National Institute for Environmental Health Sciences (NIEHS award P30 ES006096)

As one of the nation's first environmental health science research programs and the region's only center focused on gene-environment interactions (GxE), the vision of the Center for Environmental Genetics is to become a global leader in GXE research and translation. Our mission: To conduct innovative, multidisciplinary GXE research and translate discoveries to disease prevention via community empowerment, at home and around the globe. CEG investigators, trainees and collaborators are currently focused on studying gene-environment interactions in four areas, reflecting persistent and emerging population health concerns: (1) Endocrine disruption and cancer, (2) Immune and allergic diseases, (3) Cardiovascular and lipid disorders, and (4) Neurological and behavioral disorders.

Group photos of some CEG faculty and trainees 2015

Some of the many faces of the CEG. The Center is comprised of more than 75 geneticists, epidemiologists, toxicologists, immunologists, cancer specialists, postdoctoral fellows and other investigators throughout the University of Cincinnati and Cincinnati Children's Hospital Medical Center.

 CEG investigators continue to enhance our understanding of the early origins of disease; windows of susceptibility; the interplay between genetics and epigenetics; genomics, epigenomics and other -omics (proteomics, metabolomics, metagenomics, and metallomics); the influence of lifestyle modifiers such as diet or stress on epigenetic reprogramming; and finally the data void related to lifelong editing of early developmental programming and the potential for transgenerational effects. Through its ground-breaking work, the CEG seeks to advance precision medicine-based disease risk assessment, monitoring, prevention and therapies.

Photograph of Dr. Shuk-Mei Ho, Director, Center for Environmental Genetics (CEG) The CEG is led by Shuk-Mei Ho, PhD, Jacob G. Schmidlapp Professor and Chair of the Department of Environmental Health, Associate Dean for Basic Research in the UC College of Medicine, and Director of the Cincinnati Cancer Center. In 2015 Dr. Ho received the University's prestigious Rieveschl Award for Distinguished Scientific Research, based on the respect and admiration of her peers. She is a 2017 recipient of the Drake Medal, the highest honor conferred by the College of Medicine, and a nationally and internationally recognized leader in endocrine disruptor and cancer research. She has been profiled in the Journal of Endocrinology and Cancer, 2014 Aug;21(4):19-24. PMID: 24928923.

Center for Environmental Genetics Core leaders CEG Core leaders pause to celebrate the Center’s $8.1 million renewal award from the National Institute of Environmental Health Sciences (NIEHS P30 ES006096). L-R: Nicholas Newman, DO, MS, FAAP; Co-Director, Community Engagement Core (CEC). Mario Medvedovic, PhD; Director, BioinformaticsCore. Erin N. Haynes, DrPH, MS; CEC Director. Alvaro Puga, PhD; CEG Associate Director. Susan Pinney, PhD; CEG Deputy Director, and Director, Integrative Health Sciences Facility Core (IHSFC). Shuk-Mei Ho, PhD; Jacob G. Schmidlapp Professor and Chair, Department of Environmental Health; Director, CEG. Yuet-Kin (Ricky) Leung, PhD; Director, Integrative Technologies Support (ITS) Core. Aimin Chen, MD, PhD, CEG Associate Director; Co-Director, Pilot Projects Program; and Co-Director, IHSFC. Jagjit S. Yadav, PhD; Director, Pilot Projects Program. Not pictured in this photograph: Jarek Meller, PhD; Co-Director, Bioinformatics Core. Daniel Woo, MS, MD; Associate Director of Clinical/Translational Research and Associate Director, Career Development initiatives. Changchun Xie, PhD; Biostatistician, IHSFC.