Translational Research Support Core

Led by Kelly Brunst, Ph.D. and Jack Rubinstein, MD, the Translational Research Support Core (TRSC) facilitates investigations that enhance "forward and back" translational research of environmental factors in disease causation. TRSC aims are accomplished through expert consultative services in medicine, epidemiology, statistics, exposure assessment, and informatics tools, as well as clinical research conferences that highlight opportunities for translational research in environmental health. Our goals is to accelerate the transfer of basic biomedical knowledge from the laboratory to applications in prevention, early detection, and treatment, including public policy changes toward improved environmental and human health. We provide consultations on environmental epidemiology, data management & sharing (see, e.g., below), and both traditional and cutting-edge statistical approaches, including analysis of microarray and deep sequencing data, in conjunction with the CEG Bioinformatics Core.

Data Management and Sharing (DMS) | Biospecimen Sharing | Training and Resources

• NEW Data Management & Sharing Plan Hints (Hint sheet, PDF)
• NEW Data Management & Sharing Plan Hints (Slides, PDF)
• NIH Policy for Data Management and Sharing (PDF)
• NIH Policy for Data Management and Sharing Webinar (PPT)
• Data and Biospecimen Sharing Workshop, 2015 Oct 15 (See full list of videos here)
• The many benefits of sharing (Video: Susan Pinney, PhD)
• Setting the stage for sharing (PPT 1 and 2: Susan Pinney, PhD)
• Sample sharing policy: Procedures to access FCC database & biosamples (PDF)
• Public repositories for deposition and sharing of "omics" data (Video: Scott Langevin, PhD)
• Public repositories for deposition and sharing of "omics" data (PPT: Scott Langevin, PhD)  
• NIH Genomic Data Sharing Policy (PDF)
• Genomic Data Sharing: Supplemental Information (PDF)
• The HOME Study (PPT: Kimberly Yolton, PhD)

Further Resources 

• TRSC Pannel of Experts Expert consultations on study design, human subjects, et al.
  
• Fernald Community Cohort
• Human Biomonitoring Resources
• MEB-Labs Database

Human Subjects Studies and Human Clinical Trials Research

• Navigating ASSIST (MP4): Application Submission System & Interface for Submission Tracking (ASSIST) used by NIH (including NIEHS) and other Public Health Service agencies. Required human subjects enrollment reporting, etc., online workshop with NIEHS specialist Martha Barnes, MS. For the webinar recording, click here (mp4 file); for the presenter's PowerPoint slides click here (PDF).