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Portrait phoo of Aruni Bhatnagar PhDOn August 30 the CEG welcomed Aruni Bhatnagar, Ph.D., FAHA, who spoke on the Green Heart Louisville Project: Studying the Relationship between Greenness and Health. Dr. Bhatnagar is the Smith & Lucille Gibson Professor of Medicine at the University of Louisville and Chief of the Division of Environmental Medicine.  He also serves as Director of the Christina Lee Brown Envirome Institute and Career Development Director for U of L's Center for Integrative Environmental Health Science (CIEHS P30 ES030283). Read more about Dr. Bhatnagar's work.  A recording of Dr. Bhatnagar's presentation will be made available on the DEPHS website page for Departmental Seminars.

Click here for News at a Glance 2023 June (PDF)

Click here for News at a Glance 2023 July August (PDF)

The many benefits of CEG membership include access to state-of-the-art shared equipment and matching funds for the use of Core facilities and services. View CEG member benefits. The opportunity to apply for CEG membership is by invitation.  If you wish to nominate for CEG membership a mentee or colleague who is engaged in gene-environment (GxE) research or embarking on the study of environmental exposures and their impact on human development and health, please contact us for an investigator application form.  Contact the CEG.

Save the Date! Wednesday, November 8, CEG Annual Research Symposium, which will showcase the work of recent CEG Pilot awardees and funding returns on investment. Keynote Speaker: Christine Whittaker, Ph.D. Director of the Division of Science Integration, National Institute for Occupational Safety and Health (NIOSH). Dr. Whittaker will address the translation of research findings to policy impact.

We are pleased to share the audiovisual recording of the standing-room-only Workshop on Single-Cell RNA Sequencing hosted by the CEG Integrative Technologies Support (ITS) Core. Expert presenters and topics included:

  • Mario Medvedovic, PhD, Director of the UC Division of Biostatistics and Bioinformatics and leader of the CEG Bioinformatics Core, spoke on Analyzing and learning from scRNA-seq data.  
  • Chia-I Ko, PhD, Adjunct Assistant Professor, Division of Environmental Genetics & Molecular Toxicology, and 2022 CEG Time-Sensitive Response (TSR) award recipient. Dr. Ko discussed the Identification of AHR function in preimplantation embryonic differentiation by single-cell RNA sequencing.
  • Rathnakumar Kumaragurubaran, Ph.D., Assistant Professor, Pediatrics & Developmental Biology, and Director, scRNA-seq Core, Cincinnati Children's Hospital Medical Center (CCHMC).  Dr. Kumaragurubaran provided an Overview of the CCHMC Single Cell Genomics Core and its services.

View the sc-RNA Seq workshop

Integrative Technologies Support (ITS) Core Funding Available

CEG members are eligible for ITS Subsidies (i.e., matching funds) for use of certain cores and services, including Bioinformatics support. PIs with currently funded CEG Pilot awards may receive pro bono Bioinformatics support for the CEG-funded project.  ITS subsidies (matching funds) must be requested before services are obtained.  Details and an application form can be obtained on the  ITS Core Web page

Portrait of Xiang Zhang PhDThe Genomics and Epigenomics Sequencing Core (GESC) directed by Xiang Zhang, PhD, has a convenient online form for requesting services: View the GESC request form.  As of February 2023, UC investigators are required to provide billing and service information via Stratocore before sample submission: View the Stratocore guidance.

CEG investigators who use GESC services should self-identify as CEG members, in order to enhance Center reporting of research productivity. CEG members also should indicate on the form whether they would additionally like their data to be transferred to the CEG Bioinformatics Core (Director: Mario Medvedovic, PhD). The Bioinformatics Core offers long-term data storage, as well as options for highly sophisticated data analysis.

Endocrine Disrupting Chemicals Research Focus Group meets on the 2nd Thursday of each month. All are welcome.  For details please contact Katherine Burns, PhD, Assistant Professor, Department of Environmental and Public Health Sciences. For details about the CEG's ImmunoToxicology Forum contact Jagjit Yadav, PhD

The research interests of CEG New Investigator Awardee (NIA 2022--2024) Photo of Nalinikanth Kotagiri, PhDNalinikanth Kotagiri, Ph.D., MBBS, Assistant Professor, UC College of Pharmacy are primarily in therapeutic agents; but in 2021 he received a $484,000 DoD grant to protect skin from ultraviolet light: MRP Idea Award: “Engineering skin microbiome to generate natural sunscreens for prevention of melanoma” (Role PI. 7/1/21 – 6/30/24). Mentor: Zalfa Abdel-Malek, PhD. More recently, Dr. Kotagiri received a half-million dollar R01 award from the National Health Lung and Blood Institute for his study of "Siderophore-based molecular imaging of pulmonary infections." (Role PI. 7/1/23--6/30/28).  The R01 study aims to develop a targeted, pathogen-specific imaging modality that could detect bacteria in the lower airways and differentiate bacterial from viral infection non-invasively, in turn advancing our understanding of acute exacerbations in COPD (i.e., AECOPD) and the development of preemptive treatment paradigms.

On a biennial basis, the Center for Environmental Genetics may recognize up to three New Investigator Awardees (NIA’s) for a 2-year term. These are promising junior tenure-track faculty members with a demonstrated interest in environmental health science. NIA’s receive $25,000 in salary support and associated benefits each year, contingent on 1st year performance.  Applications for New Investigator Awards must include a nomination letter from the proposed mentor, copies of the applicant’s and mentor’s CVs, and a personal statement by the applicant specifying his or her plans for environmental health research over the 2-years of CEG funding. The statement should include planned NIEHS grant submissions. 

The Application Submission System & Interface for Submission Tracking (ASSIST) system is used to submit applications electronically to NIEHS and other NIH agencies. It is also used to ensure PIs' compliance with timely reporting of Human Subjects Study inclusion enrollment data, etc. Delays and errors in Human Subjects reporting via ASSIST can jeopardize individual and Center funding; hence, this guidance on Navigating ASSIST for Human Subjects and Clinical Trials, is important for PIs and their staff.

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Department of Environmental and Public Health Sciences
Center for Environmental Genetics
Kettering Lab Building
Room 210
160 Panzeca Way
Cincinnati, OH 45267-0056
Mail Location: 0056
Phone: 513-558-3646