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Click here for News at a Glance 2023 Oct
In the past year, the Genomics, Epigenomics and Sequencing Core (GESC) processed a larger number of samples than ever before. Thanks to the leadership of the Department of Environmental and Public Health Sciences, the GESC now has more lab and office space, and more services to support your research: Read more about the GESC by clicking here. The GESC also has a new billing system via UC Stratocore for all users from UC, CCHMC and external institutions. Questions? Send an email to Ellen by clicking here and and copy Dr. Xiang Zhang by clicking here.
Recent CEG Pilot awardee Debajyoti Ghosh, PhD, has received an R21 award from the National institute of Allergy and Infectious Disease for his study, “Early life dysbiosis, and skin barrier function” (R21AI176276). Dr, Ghosh is a research Assistant Professor in the UC Division of Internal Medicine and a Fellow of the American Academy of Allergy, Asthma, and Immunology. His co-investigator is longtime CEG member Ian Lewkowich, PhD. R21AI176276, $157,316 in 2023 total direct costs, project start-end 11/17/23 –10/31/25. In 2021 Dr. Ghosh received a $20,000 CEG Innovator award for his study, “Elucidating the mechanism of Atopic Dermatitis induced by maternal exposure to phthalate compounds.
Associate Professor Jun Wang, PhD, a CEG New Investigator Awardee (2020 – 2022), has received a second Ohio Workforce Safety Innovation Grant. Dr. Wang has received a new FY 2024 award of nearly $1.5 million to continue work on his project, “Enhance Performance and Applications of Exposure-Protection Integrated Communicator (EPIC).” This second round of funding follows his 2023 award of $1 million for the project “Exposure-Protection Integrated Communicator (EPIC) to Improve and Promote PPE Usages in Ohio Workplace.” The total Ohio taxpayer investment of $2.5 million is to develop a proof-of-concept, prototype device called EPIC. The device is designed to give real-time insights into a worker’s environment, personal inhalation exposure levels, and the effectiveness of his or her personal protection equipment. Dr. Wang’s collaborators include CEG emeritus Sergey Grinshpun, PhD, and new CEG members Yevgen Nazarenko, PhD, assistant professor, Wei-Wen Hsu, PhD, associate professor (Department of Environmental and Public Health Sciences) as well as 2023 CEG Pilot awardee Simone Balachandran, PhD (College of Engineering and Applied Science) et al. Dr. Wang’s project also receives support from industrial partner Tisch Environmental, a UC alumni family-run business specializing in manufacturing and marketing air quality sensors and monitors.
We are pleased to share the audiovisual recording of the standing-room-only Workshop on Single-Cell RNA Sequencing hosted by the CEG Integrative Technologies Support (ITS) Core. Expert presenters and topics included: Mario Medvedovic, PhD, Analyzing and learning from scRNA-seq data; Chia-I Ko, PhD, Identification of AHR function in preimplantation embryonic differentiation by single-cell RNA sequencing; and Rathnakumar Kumaragurubaran, Ph.D., Overview of the CCHMC Single Cell Genomics Core and its services.
View the sc-RNA Seq workshop
The Endocrine Disrupting Chemicals Research Focus Group meets on the 2nd Thursday of each month. All are welcome. For details please contact Katherine Burns, PhD, Assistant Professor, Department of Environmental and Public Health Sciences. For details about the CEG's Immuno-Toxicology Forum contact Jagjit Yadav, PhD. The new Environmental Carcinogenesis Research Focus Group will meet on Monday October 23 from 12 Noon to 1:00 PM in MSB E115. For details about the Environmental Carcinogenesis Research Focus Group, which is a joint endeavor of the UC Cancer Center and Center for Environmental Genetics, please contact Jennifer Ray at rayjl@ucmail.uc.edu.
Benefits of CEG membership include access to state-of-the-art shared equipment and matching funds for the use of Core facilities and services. CEG Membership Benefits. The opportunity to apply for CEG membership is by invitation. If you wish to nominate a mentee or colleague who is engaged in gene-environment (GxE) research or embarking on the study of environmental exposures and their impact on human development and health, please contact us for an investigator application form.
CEG members are eligible for ITS Subsidies (i.e., matching funds) for use of certain cores and services, including Bioinformatics support. PIs with currently funded CEG Pilot awards may receive pro bono Bioinformatics support for the CEG-funded project. ITS subsidies (matching funds) must be requested before services are obtained. Details and an application form can be obtained on the ITS Core Web page
Endocrine Disrupting Chemicals Research Focus Group meets on the 2nd Thursday of each month. All are welcome. For details please contact Katherine Burns, PhD, Assistant Professor, Department of Environmental and Public Health Sciences. For details about the CEG's ImmunoToxicology Forum contact Jagjit Yadav, PhD. The new Environmental Carcinogenesis Research Focus Group meets on the last Monday of each month from 12 Noon to 1:00 PM via TEAMS and in MSB E115. For details about the Environmental Carcinogenesis Research Focus Group, which is a joint endeavor of the UC Cancer Center and Center for Environmental Genetics, please contact Jennifer Ray at rayjl@ucmail.uc.edu.
The Application Submission System & Interface for Submission Tracking (ASSIST) system is used to submit applications electronically to NIEHS and other NIH agencies. It is also used to ensure PIs' compliance with timely reporting of Human Subjects Study inclusion enrollment data, etc. Delays and errors in Human Subjects reporting via ASSIST can jeopardize individual and Center funding; hence, this guidance on Navigating ASSIST for Human Subjects and Clinical Trials, is important for PIs and their staff.