Wang Laboratory

Peer Reviewed Publications

2021

Tang, Xin; Angst, Gabrielle; Haas, Michael; Yang, Fuchun; Wang, Chenran 2021. The Characterization of a Subependymal Giant Astrocytoma-Like Cell Line from Murine Astrocyte with mTORC1 Hyperactivation. International journal of molecular sciences, 22 8,

Wang, Chenran; Haas, Michael A; Yeo, Syn Kok; Paul, Ritama; Yang, Fuchun; Vallabhapurapu, Subrahmanya; Qi, Xiaoyang; Plas, David R; Guan, Jun-Lin 2021. Autophagy mediated lipid catabolism facilitates glioma progression to overcome bioenergetic crisis. British journal of cancer, ,

Wang, Chenran; Haas, Michael; Yeo, Syn Kok; Sebti, Salwa; Fernández, Álvaro F; Zou, Zhongju; Levine, Beth; Guan, Jun-Lin 2021. Enhanced autophagy in Becn1F121A/F121A knockin mice counteracts aging-related neural stem cell exhaustion and dysfunction. Autophagy, , 1-14

Liu, Hang; Wang, Chenran; Yi, Fei; Yeo, Syn; Haas, Michael; Tang, Xin; Guan, Jun-Lin 2021. Non-canonical function of FIP200 is required for neural stem cell maintenance and differentiation by limiting TBK1 activation and p62 aggregate formation. Scientific reports, 11 1, 23907

2020

Deng, Shan; Essandoh, Kobina; Wang, Xiaohong; Li, Yutian; Huang, Wei; Chen, Jing; Peng, Jiangtong; Jiang, Ding-Sheng; Mu, Xingjiang; Wang, Chenran; Peng, Tianqing; Guan, Jun-Lin; Wang, Yigang; Jegga, Anil; Huang, Kai; Fan, Guo-Chang 2020. Tsg101 positively regulates P62-Keap1-Nrf2 pathway to protect hearts against oxidative damage. Redox biology, , 101453

Chen, Qixin; Shao, Xintian; Hao, Mingang; Fang, Hongbao; Guan, Ruilin; Tian, Zhiqi; Li, Miaoling; Wang, Chenran; Ji, Liangnian; Chao, Hui; Guan, Jun-Lin; Diao, Jiajie 2020. Quantitative analysis of interactive behavior of mitochondria and lysosomes using structured illumination microscopy. Biomaterials, 250 , 120059

Yang, Fuchun; Sun, Shaogang; Wang, Chenran; Haas, Michael; Yeo, Syn; Guan, Jun-Lin 2020. Targeted therapy for mTORC1-driven tumours through HDAC inhibition by exploiting innate vulnerability of mTORC1 hyper-activation. British journal of cancer, ,

Yeo, Syn Kok; Wang, Chenran; Guan, Jun-Lin 2020. Role of FIP200 in inflammatory processes beyond its canonical autophagy function. Biochemical Society transactions, ,

2019

Wang, Chenran; Haas, Michael A; Yang, Fuchun; Yeo, Syn; Okamoto, Takako; Chen, Song; Wen, Jian; Sarma, Pranjal; Plas, David R; Guan, Jun-Lin 2019. Autophagic lipid metabolism sustains mTORC1 activity in TSC-deficient neural stem cells. Nature metabolism, 1 11, 1127-1140

Wang, Chenran; Haas, Michael A., Yang, Fuchun; Yeo, Syn; Okamoto, Takako; Chen, Song; Wen, Jian; Sarma, Pranjal; Plas, David R.; Guan, Jun-Lin 11-11-2019. Autophagic lipid metabolism sustains mTORC1 activity in TSC-deficient neural stem cells Nature Metabolism, 1, , 1127–1140