Waltz Laboratory

Peer Reviewed Publications

2023

Hunt, Brian G; Fox, Levi H; Davis, James C; Jones, Angelle; Lu, Zhixin; Waltz, Susan E 2023. An Introduction and Overview of RON Receptor Tyrosine Kinase Signaling. Genes, 14 2,

Oropeza, Elena; Seker, Sinem; Carrel, Sabrina; Mazumder, Aloran; Lozano, Daniel; Jimenez, Athena; VandenHeuvel, Sabrina N; Noltensmeyer, Dillon A; Punturi, Nindo B; Lei, Jonathan T; Lim, Bora; Waltz, Susan E; Raghavan, Shreya A; Bainbridge, Matthew N; Haricharan, Svasti 2023. Molecular portraits of cell cycle checkpoint kinases in cancer evolution, progression, and treatment responsiveness. Science advances, 9 26, eadf2860

Hunt, Brian G; Davis, James C; Fox, Levi H; Vicente-Muñoz, Sara; Lester, Carissa; Wells, Susanne I; Waltz, Susan E 2023. RON-augmented cholesterol biosynthesis in breast cancer metastatic progression and recurrence. Oncogene, 42 21, 1716-1727

2022

Ruiz-Torres, Sasha J; Bourn, Jennifer R; Benight, Nancy M; Hunt, Brian G; Lester, Carissa; Waltz, Susan E 2022. Macrophage-mediated RON signaling supports breast cancer growth and progression through modulation of IL-35. Oncogene, 41(3) Jan, 321-333

Hunt, Brian G; Jones, Angelle; Lester, Carissa; Davis, James C; Benight, Nancy M; Waltz, Susan E 2022. RON (MST1R) and HGFL (MST1) Co-Overexpression Supports Breast Tumorigenesis through Autocrine and Paracrine Cellular Crosstalk. Cancers, 14 10,

Brown, Nicholas E; Jones, Angelle; Hunt, Brian G; Waltz, Susan E 2022. Prostate tumor RON receptor signaling mediates macrophage recruitment to drive androgen deprivation therapy resistance through Gas6-mediated Axl and RON signaling. The Prostate, ,

Vicente-Muñoz, Sara; Hunt, Brian G; Lange, Taylor E; Wells, Susanne I; Waltz, Susan E 2022. NMR-based metabolomic analysis identifies RON-DEK-?-catenin dependent metabolic pathways and a gene signature that stratifies breast cancer patient survival. PloS one, 17 9, e0274128

2021

Bourn, Jennifer R; Ruiz-Torres, Sasha J; Hunt, Brian G; Benight, Nancy M; Waltz, Susan E 2021. Tumor cell intrinsic RON signaling suppresses innate immune responses in breast cancer through inhibition of IRAK4 signaling. Cancer letters, 503 , 75-90

Wicker, Christina A; Hunt, Brian G; Krishnan, Sunil; Aziz, Kathryn; Parajuli, Shobha; Palackdharry, Sarah; Elaban, William R; Wise-Draper, Trisha M; Mills, Gordon B; Waltz, Susan E; Takiar, Vinita 2021. Glutaminase inhibition with telaglenastat (CB-839) improves treatment response in combination with ionizing radiation in head and neck squamous cell carcinoma models. Cancer letters, 502 , 180-188

2020

Hunt, Brian G; Wicker, Christina A; Bourn, Jennifer R; Lower, Elyse E; Takiar, Vinita; Waltz, Susan E 2020. MST1R (RON) expression is a novel prognostic biomarker for metastatic progression in breast cancer patients. Breast cancer research and treatment, ,

Sullivan, Camille; Brown, Nicholas E; Vasiliauskas, Juozas; Pathrose, Peterson; Starnes, Sandra L; Waltz, Susan E 2020. Prostate Epithelial RON Signaling Promotes M2 Macrophage Activation to Drive Prostate Tumor Growth and Progression. Molecular cancer research : MCR, ,

Pease, Nicholas A; Shephard, Miranda S; Sertorio, Mathieu; Waltz, Susan E; Vinnedge, Lisa M Privette 2020. DEK Expression in Breast Cancer Cells Leads to the Alternative Activation of Tumor Associated Macrophages. Cancers, 12 7,

2019

Babicky, Michele L; Harper, Megan M; Chakedis, Jeffery; Cazes, Alex; Mose, Evangeline S; Jaquish, Dawn V; French, Randall P; Childers, Betzaira; Alakus, Hakan; Schmid, Michael C; Foubert, Phillippe; Miyamoto, Jaclyn; Holman, Patrick J; Walterscheid, Zakkary J; Tang, Chih-Min; Varki, Nissi; Sicklick, Jason K; Messer, Karen; Varner, Judith A; Waltz, Susan E; Lowy, Andrew M 2019. MST1R kinase accelerates pancreatic cancer progression via effects on both epithelial cells and macrophages. Oncogene, ,

Ge, Chunmin; Vilfranc, Chrystelle L; Che, Lixiao; Pandita, Raj K; Hambarde, Shashank; Andreassen, Paul R; Niu, Liang; Olowokure, Olugbenga; Shah, Shimul; Waltz, Susan E; Zou, Lee; Wang, Jiang; Pandita, Tej K; Du, Chunying 2019. The BRUCE-ATR signaling axis is required for accurate DNA replication and suppression of liver cancer development. Hepatology (Baltimore, Md.), ,