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Fan Laboratory

Fan Lab Members


The long-term goal of our research is to explore the molecular basis of vascular disease and the intersection of vascular disease and cancer. We aim to uncover novel therapeutic targets and approaches to prevent and treat cardiovascular disease and cancer. 

We recently demonstrated that transcription factor EB (TFEB), a master regulator of autophagy and lysosome biogenesis, is critical to maintain vascular wall homeostasis.  The overall goal of the Fan laboratory is to identify novel therapeutic targets for the treatment of a variety of vascular-related human diseases.

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Department of
Cancer Biology

Vontz Center for Molecular Studies
3125 Eden Avenue
PO Box 670521
Cincinnati, OH 45267-0521

Mail Location: 0521
Phone: 513-558-5323
Fax: 513-558-1190