Breast Cancer Research Program (BCRP) Research Resources
Our breast cancer research program currently has the following research resources available for the breast cancer research community with more to come, thanks to the generous support from the University of Cincinnati Cancer Center, Ride Cincinnati Foundation, and Waddell Family Fund. You may request these samples from the UCCC Biospecimen Shared Resource following the standard sample request procedure. Best wishes for your research and please acknowledge the above support in your presentation and publication when appropriate.
Patient-Derived Organoid (PDO) models:
| PDO Model ID | Specimen ID | Cancer type | Diagnosis Subtype | PDO Media | Notes | Funding Sources |
|---|---|---|---|---|---|---|
| UCBCRP-PDO001 | MAL1527-TU1-PDO | IDC | ER-, PR-, HER2 Moderate | M1 | UCCC, Ride Cincinnati | |
| UCBCRP-PDO002 | MAL1409-TU1-PDO | LDC | ER+, PR+, HER2(2+ with Amp) | M1 | IHC Confirmed Subtype of PDO Tumor | UCCC, Ride Cincinnati |
| UCBCRP-PDO003 | MAL1590-TU1-PDO | IDC, focal lobular features | ER+, PR+, HER2- | M2 | IHC Confirmed Subtype of PDO Tumor | UCCC, Ride Cincinnati |
| UCBCRP-PDO004 | MAL1592-TU1-PDO | Squamous Cell carcinoma, keratinizing | ER-, PR-, HER2- | M1 | IHC Confirmed Subtype of PDO Tumor | UCCC, Ride Cincinnati, Waddell Family Fund |
| UCBCRP-PDO005 | MAL1670-TU1-PDO | Invasive Carcinoma | ER+, PR+, HER2- | M2 | UCCC, Ride Cincinnati | |
| UCBCRP-PDO006 | MAL1671-TU1-PDO | Mucinous carcinoma | ER+, PR+, HER2- | M2 | UCCC, Ride Cincinnati | |
| UCBCRP-PDO007 | MAL1772-TU1-PDO | IDC | ER+, PR+, HER2- | M2 | UCCC, Ride Cincinnati |
Patient-Derived Xenograft (PDX) Model:
| PDO Model ID | Specimen ID | Cancer type | Diagnosis Subtype | PDO Media | Notes | Funding Sources |
|---|---|---|---|---|---|---|
| UCBCRP-PDX001 | MAL1527 -TU1-PDX | IDC | ER-, PR-, HER2 Moderate | M1 | IHC Confirmed Subtype of PDX Tumor | UCCC, Ride Cincinnati |
Normal breast tissue (NBT) PDOs:
| PDO Model ID | Specimen ID | PDO Media | Notes | Funding Sources |
|---|---|---|---|---|
| UCBCRP-NBT001 | MAL1527-NO1-PDO | M2 | Matched with UCBCRP-PDX001 and UCBCRP-PDO001 | UCCC, Ride Cincinnati |
| UCBCRP-NBT002 | MAL1590 -NO1-PDO | M2 | Matched with UCBCRP-PDO003 | UCCC, Ride Cincinnati |
| UCBCRP-NBT003 | MAL1579 -NO1-PDO | M2 | UCCC, Ride Cincinnati | |
| UCBCRP-NBT004 | MAL1671 -NO1-PDO | M2 | Matched with UCBCRP-PDO006 | UCCC, Ride Cincinnati, Waddell Family Fund |
| UCBCRP-NBT005 | MAL1765 -NO1-PDO | M2 | Matched tumor PDO is slow growing but will become available | UCCC, Ride Cincinnati |
Protocols:
BCRP PDX protocol 0923 (pdf)
BCRP PDO Protocol 0923 (pdf)
Contact Us
Department of Cancer BiologyVontz Center for Molecular Studies
3125 Eden Avenue
PO Box 670521
Cincinnati, OH 45267-0521
Mail Location: 0521
Phone: 513-558-5323
Fax: 513-558-1190
Email: cbrecruitment@uc.edu