Education/CredentialsDoctoral Degree: University of Pittsburgh School of Medicine (Neuroscience)Undergraduate: University of Notre Dame (Biological Sciences) Contact Information Medical Sciences Building 5253 Office 513-558-3567 Email hartinja@ucmail.uc.edu Research InterestsAreas of expertise - pathophysiology and treatment of traumatic brain injury and stroke, with emphasis on spreading depression, seizures, and neuromonitoring Peer Reviewed Publications Claassen, Jan; Akbari, Yama; Alexander, Sheila; Bader, Mary Kay; Bell, Kathleen; Bleck, Thomas P; Boly, Melanie; Brown, Jeremy; Chou, Sherry H-Y; Diringer, Michael N; Edlow, Brian L; Foreman, Brandon; Giacino, Joseph T; Gosseries, Olivia; Green, Theresa; Greer, David M; Hanley, Daniel F; Hartings, Jed A; Helbok, Raimund; Hemphill, J Claude; Hinson, H E; Hirsch, Karen; Human, Theresa; James, Michael L; Ko, Nerissa; Kondziella, Daniel; Livesay, Sarah; Madden, Lori K; Mainali, Shraddha; Mayer, Stephan A; McCredie, Victoria; McNett, Molly M; Meyfroidt, Geert; Monti, Martin M; Muehlschlegel, Susanne; Murthy, Santosh; Nyquist, Paul; Olson, DaiWai M; Provencio, J Javier; Rosenthal, Eric; Sampaio Silva, Gisele; Sarasso, Simone; Schiff, Nicholas D; Sharshar, Tarek; Shutter, Lori; Stevens, Robert D; Vespa, Paul; Videtta, Walter; Wagner, Amy; Ziai, Wendy; Whyte, John; Zink, Elizabeth; Suarez, Jose I 2021. Proceedings of the First Curing Coma Campaign NIH Symposium: Challenging the Future of Research for Coma and Disorders of Consciousness. Neurocritical care, 35 Suppl 1, 4-23Foreman, Brandon; Lee, Hyunjo; Mizrahi, Moshe A; Hartings, Jed A; Ngwenya, Laura B; Privitera, Michael; Tortella, Frank C; Zhang, Nanhua; Kramer, Joel H 2021. Seizures and Cognitive Outcome After Traumatic Brain Injury: A Post Hoc Analysis. Neurocritical care, , Hartings, Jed A; Carroll, Christopher P; Lee, Gregory 2021. Spreading Diffusion-Restriction Events in the Gyrencephalic Brain After Subarachnoid Hemorrhage Revealed by Continuous Magnetic Resonance Imaging. Neurocritical care, , Jewell, Sharon; Hobson, Stephen; Brewer, Grant; Rogers, Michelle; Hartings, Jed A; Foreman, Brandon; Lavrador, José-Pedro; Sole, Michael; Pahl, Clemens; Boutelle, Martyn G; Strong, Anthony J 2021. Development and Evaluation of a Method for Automated Detection of Spreading Depolarizations in the Injured Human Brain. Neurocritical care, 35 Suppl 2, 160-175Barhorst, Kinsey A; Alfawares, Yara; McGuire, Jennifer L; Danzer, Steve C; Hartings, Jed A; Ngwenya, Laura B 2020. Remote and Persistent Alterations in Glutamate Receptor Subunit Composition Induced by Spreading Depolarizations in Rat Brain. Cellular and molecular neurobiology, , Hartings, Jed A; Andaluz, Norberto; Bullock, M Ross; Hinzman, Jason M; Mathern, Bruce; Pahl, Clemens; Puccio, Ava; Shutter, Lori A; Strong, Anthony J; Vagal, Achala; Wilson, J Adam; Dreier, Jens P; Ngwenya, Laura B; Foreman, Brandon; Pahren, Laura; Lingsma, Hester; Okonkwo, David O 2020. Prognostic Value of Spreading Depolarizations in Patients With Severe Traumatic Brain Injury. JAMA neurology, 77 4, 489-499Helbok, Raimund; Hartings, Jed A; Schiefecker, Alois; Balança, Baptiste; Jewel, Sharon; Foreman, Brandon; Ercole, Ari; Balu, Ramani; Ayata, Cenk; Ngwenya, Laura; Rosenthal, Eric; Boutelle, Martyn G; Farkas, Eszter; Dreier, Jens P; Fabricius, Martin; Shuttleworth, C William; Carlson, Andrew 2020. What Should a Clinician Do When Spreading Depolarizations are Observed in a Patient? Neurocritical care, 32 1, 306-310Provencio, J Javier; Hemphill, J Claude; Claassen, Jan; Edlow, Brian L; Helbok, Raimund; Vespa, Paul M; Diringer, Michael N; Polizzotto, Len; Shutter, Lori; Suarez, Jose I; Stevens, Robert D; Hanley, Daniel F; Akbari, Yama; Bleck, Thomas P; Boly, Melanie; Foreman, Brandon; Giacino, Joseph T; Hartings, Jed A; Human, Theresa; Kondziella, Daniel; Ling, Geoffrey S F; Mayer, Stephan A; McNett, Molly; Menon, David K; Meyfroidt, Geert; Monti, Martin M; Park, Soojin; Pouratian, Nader; Puybasset, Louis; Rohaut, Benjamin; Rosenthal, Eric S; Schiff, Nicholas D; Sharshar, Tarek; Wagner, Amy; Whyte, John; Olson, DaiWai M 2020. The Curing Coma Campaign: Framing Initial Scientific Challenges-Proceedings of the First Curing Coma Campaign Scientific Advisory Council Meeting. Neurocritical care, 33 1, 1-12Shuttleworth, C William; Andrew, R David; Akbari, Yama; Ayata, Cenk; Balu, Ramani; Brennan, K C; Boutelle, Martyn; Carlson, Andrew P; Dreier, Jens P; Fabricius, Martin; Farkas, Eszter; Foreman, Brandon; Helbok, Raimund; Henninger, Nils; Jewell, Sharon L; Jones, Stephen C; Kirov, Sergei A; Lindquist, Britta E; Maciel, Carolina B; Okonkwo, David; Reinhart, Katelyn M; Robertson, R Meldrum; Rosenthal, Eric S; Watanabe, Tomas; Hartings, Jed A 2020. Which Spreading Depolarizations Are Deleterious To Brain Tissue? Neurocritical care, 32 1, 317-322Dreier, Jens P; Major, Sebastian; Lemale, Coline L; Kola, Vasilis; Reiffurth, Clemens; Schoknecht, Karl; Hecht, Nils; Hartings, Jed A; Woitzik, Johannes 2019. Correlates of Spreading Depolarization, Spreading Depression, and Negative Ultraslow Potential in Epidural Versus Subdural Electrocorticography. Frontiers in neuroscience, 13 , 373Eriksen, Nina; Pakkenberg, Bente; Rostrup, Egill; Okonkwo, David O; Mathern, Bruce; Shutter, Lori A; Strong, Anthony J; Woitzik, Johannes; Pahl, Clemens; Dreier, Jens P; Martus, Peter; Lauritzen, Martin J; Fabricius, Martin; Hartings, Jed A 2019. Neurostereologic Lesion Volumes and Spreading Depolarizations in Severe Traumatic Brain Injury Patients: A Pilot Study. Neurocritical care, 30 3, 557-568Eriksen, Nina; Rostrup, Egill; Fabricius, Martin; Scheel, Michael; Major, Sebastian; Winkler, Maren K L; Bohner, Georg; Santos, Edgar; Sakowitz, Oliver W; Kola, Vasilis; Reiffurth, Clemens; Hartings, Jed A; Vajkoczy, Peter; Woitzik, Johannes; Martus, Peter; Lauritzen, Martin; Pakkenberg, Bente; Dreier, Jens P 2019. Early focal brain injury after subarachnoid hemorrhage correlates with spreading depolarizations. Neurology, 92 4, e326-e341Hartings, Jed A 2019. How slow can you go? Nature materials, 18 3, 194-196Lee, Hyunjo; Mizrahi, Moshe A; Hartings, Jed A; Sharma, Sameer; Pahren, Laura; Ngwenya, Laura B; Moseley, Brian D; Privitera, Michael; Tortella, Frank C; Foreman, Brandon 2019. Continuous Electroencephalography After Moderate to Severe Traumatic Brain Injury. Critical care medicine, 47 4, 574-582Santos, Edgar; Olivares-Rivera, Arturo; Major, Sebastian; Sánchez-Porras, Renán; Uhlmann, Lorenz; Kunzmann, Kevin; Zerelles, Roland; Kentar, Modar; Kola, Vasilis; Aguilera, Adrian Hernández; Herrera, Mildred Gutierrez; Lemale, Coline L; Woitzik, Johannes; Hartings, Jed A; Sakowitz, Oliver W; Unterberg, Andreas W; Dreier, Jens P 2019. Lasting s-ketamine block of spreading depolarizations in subarachnoid hemorrhage: a retrospective cohort study. Critical care (London, England), 23 1, 427Carlson, Andrew P; Shuttleworth, C William; Major, Sebastian; Lemale, Coline L; Dreier, Jens P; Hartings, Jed A 2018. Terminal spreading depolarizations causing electrocortical silencing prior to clinical brain death: case report. Journal of neurosurgery, 131 6, 1773-1779Dreier, Jens P; Major, Sebastian; Foreman, Brandon; Winkler, Maren K L; Kang, Eun-Jeung; Milakara, Denny; Lemale, Coline L; DiNapoli, Vince; Hinzman, Jason M; Woitzik, Johannes; Andaluz, Norberto; Carlson, Andrew; Hartings, Jed A 2018. Terminal spreading depolarization and electrical silence in death of human cerebral cortex. Annals of neurology, 83 2, 295-310Foreman, Brandon; Ngwenya, Laura B; Stoddard, Erica; Hinzman, Jason M; Andaluz, Norberto; Hartings, Jed A 2018. Safety and Reliability of Bedside, Single Burr Hole Technique for Intracranial Multimodality Monitoring in Severe Traumatic Brain Injury. Neurocritical care, 29 3, 469-480Hartings, Jed A; Ngwenya, Laura B; Carroll, Christopher P; Foreman, Brandon 2018. Letter to the Editor. Ketamine sedation for the suppression of spreading depolarizations. Journal of neurosurgery, , 1-2Hartings, Jed A; Ngwenya, Laura B; Watanabe, Tomas; Foreman, Brandon 2018. Commentary: Detecting Cortical Spreading Depolarization with Full Band Scalp Electroencephalography: An Illusion? Frontiers in systems neuroscience, 12 , 19Lückl, Janos; Lemale, Coline L; Kola, Vasilis; Horst, Viktor; Khojasteh, Uldus; Oliveira-Ferreira, Ana I; Major, Sebastian; Winkler, Maren K L; Kang, Eun-Jeung; Schoknecht, Karl; Martus, Peter; Hartings, Jed A; Woitzik, Johannes; Dreier, Jens P 2018. The negative ultraslow potential, electrophysiological correlate of infarction in the human cortex. Brain : a journal of neurology, 141 6, 1734-1752Schinke, Christian; Horst, Viktor; Schlemm, Ludwig; Wawra, Matthias; Scheel, Michael; Hartings, Jed A; Dreier, Jens P 2018. A case report of delayed cortical infarction adjacent to sulcal clots after traumatic subarachnoid hemorrhage in the absence of proximal vasospasm. BMC neurology, 18 1, 210Cnossen, Maryse C; Huijben, Jilske A; van der Jagt, Mathieu; Volovici, Victor; van Essen, Thomas; Polinder, Suzanne; Nelson, David; Ercole, Ari; Stocchetti, Nino; Citerio, Giuseppe; Peul, Wilco C; Maas, Andrew I R; Menon, David; Steyerberg, Ewout W; Lingsma, Hester F 2017. Variation in monitoring and treatment policies for intracranial hypertension in traumatic brain injury: a survey in 66 neurotrauma centers participating in the CENTER-TBI study. Critical care (London, England), 21 1, 233Hartings JA 2017. Spreading depolarization monitoring in neurocritical care of acute brain injury Current Opinion in Critical Care, 23 2, 94Hartings, Jed A 2017. Spreading depolarization monitoring in neurocritical care of acute brain injury. Current opinion in critical care, 23 2, 94-102Hartings, Jed A; Dreier, Jens P 2017. Real-time detection of lesion development in acute brain injury. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 37 5, 1550-1552Hartings, Jed A; York, Jonathan; Carroll, Christopher P; Hinzman, Jason M; Mahoney, Eric; Krueger, Bryan; Winkler, Maren K L; Major, Sebastian; Horst, Viktor; Jahnke, Paul; Woitzik, Johannes; Kola, Vasilis; Du, Yifeng; Hagen, Matthew; Jiang, Jianxiong; Dreier, Jens P 2017. Subarachnoid blood acutely induces spreading depolarizations and early cortical infarction. Brain : a journal of neurology, 140 10, 2673-2690Maas, Andrew I R; Menon, David K; Adelson, P David; Andelic, Nada; Bell, Michael J; Belli, Antonio; Bragge, Peter; Brazinova, Alexandra; Büki, András; Chesnut, Randall M; Citerio, Giuseppe; Coburn, Mark; Cooper, D Jamie; Crowder, A Tamara; Czeiter, Endre; Czosnyka, Marek; Diaz-Arrastia, Ramon; Dreier, Jens P; Duhaime, Ann-Christine; Ercole, Ari; van Essen, Thomas A; Feigin, Valery L; Gao, Guoyi; Giacino, Joseph; Gonzalez-Lara, Laura E; Gruen, Russell L; Gupta, Deepak; Hartings, Jed A; Hill, Sean; Jiang, Ji-Yao; Ketharanathan, Naomi; Kompanje, Erwin J O; Lanyon, Linda; Laureys, Steven; Lecky, Fiona; Levin, Harvey; Lingsma, Hester F; Maegele, Marc; Majdan, Marek; Manley, Geoffrey; Marsteller, Jill; Mascia, Luciana; McFadyen, Charles; Mondello, Stefania; Newcombe, Virginia; Palotie, Aarno; Parizel, Paul M; Peul, Wilco; Piercy, James; Polinder, Suzanne; Puybasset, Louis; Rasmussen, Todd E; Rossaint, Rolf; Smielewski, Peter; Söderberg, Jeannette; Stanworth, Simon J; Stein, Murray B; von Steinbüchel, Nicole; Stewart, William; Steyerberg, Ewout W; Stocchetti, Nino; Synnot, Anneliese; Te Ao, Braden; Tenovuo, Olli; Theadom, Alice; Tibboel, Dick; Videtta, Walter; Wang, Kevin K W; Williams, W Huw; Wilson, Lindsay; Yaffe, Kristine 2017. Traumatic brain injury: integrated approaches to improve prevention, clinical care, and research. The Lancet. Neurology, 16 12, 987-1048Milakara, Denny; Grozea, Cristian; Dahlem, Markus; Major, Sebastian; Winkler, Maren K L; Lückl, Janos; Scheel, Michael; Kola, Vasilis; Schoknecht, Karl; Lublinsky, Svetlana; Friedman, Alon; Martus, Peter; Hartings, Jed A; Woitzik, Johannes; Dreier, Jens P 2017. Simulation of spreading depolarization trajectories in cerebral cortex: Correlation of velocity and susceptibility in patients with aneurysmal subarachnoid hemorrhage. NeuroImage. Clinical, 16 , 524-538Pinczolits A, Zdunczyk A, Dengler NF, Hecht N, Kowoll CM, Dohmen C, Graf R, Winkler MK, Major S, Hartings JA, Dreier JP, Vajkoczy P, Woitzik J. 2017. Standard-sampling microdialysis and spreading depolarizations in patients with malignant hemispheric stroke Journal of Cerebral Blood Flow and Metabolism , 37 5, 1896Pinczolits, Alexandra; Zdunczyk, Anna; Dengler, Nora F; Hecht, Nils; Kowoll, Christina M; Dohmen, Christian; Graf, Rudolf; Winkler, Maren Kl; Major, Sebastian; Hartings, Jed A; Dreier, Jens P; Vajkoczy, Peter; Woitzik, Johannes 2017. Standard-sampling microdialysis and spreading depolarizations in patients with malignant hemispheric stroke. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 37 5, 1896-19055. Wu Z, Li C, Hartings JA, Narayan R, Ahn C 2016. Polysilicon thin film developed on flexible polyimide for biomedical applications . IEEE Journal of Microelectromechanical Systems , 25 4, 585Bogdanov, Volodymyr B; Middleton, Natalie A; Theriot, Jeremy J; Parker, Patrick D; Abdullah, Osama M; Ju, Y Sungtaek; Hartings, Jed A; Brennan, K C 2016. Susceptibility of Primary Sensory Cortex to Spreading Depolarizations. The Journal of neuroscience : the official journal of the Society for Neuroscience, 36 17, 4733-43Dreier, Jens P; Fabricius, Martin; Ayata, Cenk; Sakowitz, Oliver W; William Shuttleworth, C; Dohmen, Christian; Graf, Rudolf; Vajkoczy, Peter; Helbok, Raimund; Suzuki, Michiyasu; Schiefecker, Alois J; Major, Sebastian; Winkler, Maren Kl; Kang, Eun-Jeung; Milakara, Denny; Oliveira-Ferreira, Ana I; Reiffurth, Clemens; Revankar, Gajanan S; Sugimoto, Kazutaka; Dengler, Nora F; Hecht, Nils; Foreman, Brandon; Feyen, Bart; Kondziella, Daniel; Friberg, Christian K; Piilgaard, Henning; Rosenthal, Eric S; Westover, M Brandon; Maslarova, Anna; Santos, Edgar; Hertle, Daniel; Sánchez-Porras, Renán; Jewell, Sharon L; Balança, Baptiste; Platz, Johannes; Hinzman, Jason M; Lückl, Janos; Schoknecht, Karl; Schöll, Michael; Drenckhahn, Christoph; Feuerstein, Delphine; Eriksen, Nina; Horst, Viktor; Bretz, Julia S; Jahnke, Paul; Scheel, Michael; Bohner, Georg; Rostrup, Egill; Pakkenberg, Bente; Heinemann, Uwe; Claassen, Jan; Carlson, Andrew P; Kowoll, Christina M; Lublinsky, Svetlana; Chassidim, Yoash; Shelef, Ilan; Friedman, Alon; Brinker, Gerrit; Reiner, Michael; Kirov, Sergei A; Andrew, R David; Farkas, Eszter; Güresir, Erdem; Vatter, Hartmut; Chung, Lee S; Brennan, K C; Lieutaud, Thomas; Marinesco, Stephane; Maas, Andrew Ir; Sahuquillo, Juan; Dahlem, Markus A; Richter, Frank; Herreras, Oscar; Boutelle, Martyn G; Okonkwo, David O; Bullock, M Ross; Witte, Otto W; Martus, Peter; van den Maagdenberg, Arn Mjm; Ferrari, Michel D; Dijkhuizen, Rick M; Shutter, Lori A; Andaluz, Norberto; Schulte, André P; MacVicar, Brian; Watanabe, Tomas; Woitzik, Johannes; Lauritzen, Martin; Strong, Anthony J; Hartings, Jed A 2016. Recording, analysis, and interpretation of spreading depolarizations in neurointensive care: Review and recommendations of the COSBID research group. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, , Drenckhahn, Christoph; Windler, Claudia; Major, Sebastian; Kang, Eun-Jeung; Scheel, Michael; Vajkoczy, Peter; Hartings, Jed A; Woitzik, Johannes; Dreier, Jens P 2016. Complications in Aneurysmal Subarachnoid Hemorrhage Patients With and Without Subdural Electrode Strip for Electrocorticography. Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society, 33 3, 250-9Hartings, Jed A; Li, Chunyan; Hinzman, Jason M; Shuttleworth, C William; Ernst, Griffin L; Dreier, Jens P; Wilson, J Adam; Andaluz, Norberto; Foreman, Brandon; Carlson, Andrew P 2016. Direct current electrocorticography for clinical neuromonitoring of spreading depolarizations. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, , Hartings, Jed A; Shuttleworth, C William; Kirov, Sergei A; Ayata, Cenk; Hinzman, Jason M; Foreman, Brandon; Andrew, R David; Boutelle, Martyn G; Brennan, K C; Carlson, Andrew P; Dahlem, Markus A; Drenckhahn, Christoph; Dohmen, Christian; Fabricius, Martin; Farkas, Eszter; Feuerstein, Delphine; Graf, Rudolf; Helbok, Raimund; Lauritzen, Martin; Major, Sebastian; Oliveira-Ferreira, Ana I; Richter, Frank; Rosenthal, Eric S; Sakowitz, Oliver W; Sánchez-Porras, Renán; Santos, Edgar; Schöll, Michael; Strong, Anthony J; Urbach, Anja; Westover, M Brandon; Winkler, Maren Kl; Witte, Otto W; Woitzik, Johannes; Dreier, Jens P 2016. The continuum of spreading depolarizations in acute cortical lesion development: Examining Leão's legacy. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, , Li, Chunyan; Narayan, Raj K; Wang, Ping; Hartings, Jed A 2016. Regional temperature and quantitative cerebral blood flow responses to cortical spreading depolarization in the rat. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, , Li, Chunyan; Narayan, Raj K; Wu, Pei-Ming; Rajan, Neena; Wu, Zhizhen; Mehan, Neal; Golanov, Eugene V; Ahn, Chong H; Hartings, Jed A 2016. Evaluation of microelectrode materials for direct-current electrocorticography. Journal of neural engineering, 13 1, 016008Li, Chunyan; Wu, Zhizhen; Limnuson, Kanokwan; Cheyuo, Cletus; Wang, Ping; Ahn, Chong H; Narayan, Raj K; Hartings, Jed A 2016. Development and application of a microfabricated multimodal neural catheter for neuroscience. Biomedical microdevices, 18 1, 8Toth, Peter; Szarka, Nikolett; Farkas, Eszter; Ezer, Erzsebet; Czeiter, Endre; Amrein, Krisztina; Ungvari, Zoltan; Hartings, Jed A; Buki, Andras; Koller, Akos 2016. Traumatic brain injury-induced autoregulatory dysfunction and spreading depression-related neurovascular uncoupling: Pathomechanisms, perspectives, and therapeutic implications. American journal of physiology. Heart and circulatory physiology, 311 5, H1118-H1131Winkler, Maren Kl; Dengler, Nora; Hecht, Nils; Hartings, Jed A; Kang, Eun J; Major, Sebastian; Martus, Peter; Vajkoczy, Peter; Woitzik, Johannes; Dreier, Jens P 2016. Oxygen availability and spreading depolarizations provide complementary prognostic information in neuromonitoring of aneurysmal subarachnoid hemorrhage patients. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, , Wu Z, Li C, Hartings JA, Narayan RK, Ahn C 2016. Polysilicon based flexible temperature sensor for high resolution brain temperature monitoring . Conf Proc IEEE Eng Med Biol Soc , , 500Hinzman, Jason M; DiNapoli, Vince A; Mahoney, Eric J; Gerhardt, Greg A; Hartings, Jed A 2015. Spreading depolarizations mediate excitotoxicity in the development of acute cortical lesions. Experimental neurology, 267 , 243-53Hinzman, Jason M; Gibson, Justin L; Tackla, Ryan D; Costello, Mark S; Burmeister, Jason J; Quintero, Jorge E; Gerhardt, Greg A; Hartings, Jed A 2015. Real-time monitoring of extracellular adenosine using enzyme-linked microelectrode arrays. Biosensors & bioelectronics, 74 , 512-517Hinzman, Jason; Wilson, J Adam; Mazzeo, Anna Teresa; Bullock, Ross; Hartings, Jed A 2015. Excitotoxicity and Metabolic Crisis Are Associated with Spreading Depolarizations in Severe Traumatic Brain Injury Patients. Journal of neurotrauma, , Li, Chunyan; Limnuson, Kanokwan; Wu, Zhizhen; Amin, Aseer; Narayan, Anjali; Golanov, Eugene V; Ahn, Chong H; Hartings, Jed A; Narayan, Raj K 2015. Single probe for real-time simultaneous monitoring of neurochemistry and direct-current electrocorticography. Biosensors & bioelectronics, 77 , 62-68Li, Chunyan; Wu, Pei-Ming; Wu, Zhizhen; Limnuson, Kanokwan; Mehan, Neal; Mozayan, Cameron; Golanov, Eugene V; Ahn, Chong H; Hartings, Jed A; Narayan, Raj K 2015. Highly accurate thermal flow microsensor for continuous and quantitative measurement of cerebral blood flow. Biomedical microdevices, 17 5, 9992Maas, Andrew I R; Menon, David K; Steyerberg, Ewout W; Citerio, Giuseppe; Lecky, Fiona; Manley, Geoffrey T; Hill, Sean; Legrand, Valerie; Sorgner, Annina 2015. Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI): a prospective longitudinal observational study. Neurosurgery, 76 1, 67-80Tackla, Ryan; Hinzman, Jason M; Foreman, Brandon; Magner, Mark; Andaluz, Norberto; Hartings, Jed A 2015. Assessment of Cerebrovascular Autoregulation Using Regional Cerebral Blood Flow in Surgically Managed Brain Trauma Patients. Neurocritical care, , Jeffcote, Toby; Hinzman, Jason M; Jewell, Sharon L; Learney, Robert M; Pahl, Clemens; Tolias, Christos; Walsh, Daniel C; Hocker, Sara; Zakrzewska, Agnieszka; Fabricius, Martin E; Strong, Anthony J; Hartings, Jed A; Boutelle, Martyn G 2014. Detection of spreading depolarization with intraparenchymal electrodes in the injured human brain. Neurocritical care, 20 1, 21-31Dreier, Jens P; Drenckhahn, Christoph; Woitzik, Johannes; Major, Sebastian; Offenhauser, Nikolas; Weber-Carstens, Steffen; Wolf, Stefan; Strong, Anthony J; Vajkoczy, Peter; Hartings, Jed A 2013. Spreading Ischemia After Aneurysmal Subarachnoid Hemorrhage. Acta neurochirurgica. Supplement, 115 , 125-129Hartings, Jed A; Vidgeon, Steven; Strong, Anthony J; Zacko, Chris; Vagal, Achala; Andaluz, Norberto; Ridder, Thomas; Stanger, Richard; Fabricius, Martin; Mathern, Bruce; Pahl, Clemens; Tolias, Christos M; Bullock, M Ross 2013. Surgical management of traumatic brain injury: a comparative-effectiveness study of 2 centers. Journal of neurosurgery, , Hartings, Jed A; Wilson, J Adam; Look, Andrew C; Vagal, Achala; Shutter, Lori A; Dreier, Jens P; Ringer, Andrew; Zuccarello, Mario 2013. Full-band electrocorticography of spreading depolarizations in patients with aneurysmal subarachnoid hemorrhage. Acta neurochirurgica. Supplement, 115 , 131-41Serrone, Joseph C; Wash, Erin M; Hartings, Jed A; Andaluz, Norberto; Zuccarello, Mario 2013. Venous Thromboembolism in Subarachnoid Hemorrhage. World neurosurgery, , Wilson, J Adam; Shutter, Lori A; Hartings, Jed A 2013. COSBID-M3: A Platform for Multimodal Monitoring, Data Collection, and Research in Neurocritical Care. Acta neurochirurgica. Supplement, 115 , 67-74Dreier, Jens P; Major, Sebastian; Pannek, Heinz-Wolfgang; Woitzik, Johannes; Scheel, Michael; Wiesenthal, Dirk; Martus, Peter; Winkler, Maren K L; Hartings, Jed A; Fabricius, Martin; Speckmann, Erwin-Josef; Gorji, Ali 2012. Spreading convulsions, spreading depolarization and epileptogenesis in human cerebral cortex. Brain : a journal of neurology, 135 Pt 1, 259-75Drenckhahn, Christoph; Winkler, Maren K L; Major, Sebastian; Scheel, Michael; Kang, Eun-Jeung; Pinczolits, Alexandra; Grozea, Cristian; Hartings, Jed A; Woitzik, Johannes; Dreier, Jens P 2012. Correlates of spreading depolarization in human scalp electroencephalography. Brain : a journal of neurology, 135 Pt 3, 853-68Hertle, Daniel N; Dreier, Jens P; Woitzik, Johannes; Hartings, Jed A; Bullock, Ross; Okonkwo, David O; Shutter, Lori A; Vidgeon, Steven; Strong, Anthony J; Kowoll, Christina; Dohmen, Christian; Diedler, Jennifer; Veltkamp, Roland; Bruckner, Thomas; Unterberg, Andreas W; Sakowitz, Oliver W 2012. Effect of analgesics and sedatives on the occurrence of spreading depolarizations accompanying acute brain injury. Brain : a journal of neurology, 135 Pt 8, 2390-2398Li, Chunyan; Wu, Pei-Ming; Hartings, Jed A; Wu, Zhizhen; Cheyuo, Cletus; Wang, Ping; Ledoux, David; Shutter, Lori A; Ramaswamy, Bharat Ram; Ahn, Chong H; Narayan, Raj K 2012. Micromachined lab-on-a-tube sensors for simultaneous brain temperature and cerebral blood flow measurements. Biomedical microdevices, , Li, Chunyan; Wu, Pei-Ming; Wu, Zhizhen; Ahn, Chong H; LeDoux, David; Shutter, Lori A; Hartings, Jed A; Narayan, Raj K 2012. Brain temperature measurement: A study of in vitro accuracy and stability of smart catheter temperature sensors. Biomedical microdevices, 14 1, 109-18Li, Chunyan; Wu, Zhizhen; Hartings, Jed A; Rajan, Neena; Chahine, Nadeen; Cheyuo, Cletus; Wang, Ping; Wu, Pei-Ming; Golanov, Eugene V; Ahn, Chong H; Narayan, Raj K 2012. Brain-friendly amperometric enzyme biosensor based on encapsulated oxygen generating biomaterial. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference, 2012 , 6003-6Fioravanti, Beatriz; Kasasbeh, Aimen; Edelmayer, Rebecca; Skinner, David P; Hartings, Jed A; Burklund, Ryan D; De Felice, Milena; French, Edward D; Dussor, Greg O; Dodick, David W; Porreca, Frank; Vanderah, Todd W 2011. Evaluation of cutaneous allodynia following induction of cortical spreading depression in freely moving rats. Cephalalgia : an international journal of headache, 31 10, 1090-100Hartings, Jed A; Bullock, M Ross; Okonkwo, David O; Murray, Lilian S; Murray, Gordon D; Fabricius, Martin; Maas, Andrew Ir; Woitzik, Johannes; Sakowitz, Oliver; Mathern, Bruce; Roozenbeek, Bob; Lingsma, Hester; Dreier, Jens P; Puccio, Ava M; Shutter, Lori A; Pahl, Clemens; Strong, Anthony J 2011. Spreading depolarisations and outcome after traumatic brain injury: a prospective observational study. Lancet neurology, 10 12, 1058-64Hartings, Jed A; Watanabe, Tomas; Bullock, M Ross; Okonkwo, David O; Fabricius, Martin; Woitzik, Johannes; Dreier, Jens P; Puccio, Ava; Shutter, Lori A; Pahl, Clemens; Strong, Anthony J 2011. Spreading depolarizations have prolonged direct current shifts and are associated with poor outcome in brain trauma. Brain : a journal of neurology, 134 Pt 5, 1529-40Lauritzen, Martin; Dreier, Jens Peter; Fabricius, Martin; Hartings, Jed A; Graf, Rudolf; Strong, Anthony John 2011. Clinical relevance of cortical spreading depression in neurological disorders: migraine, malignant stroke, subarachnoid and intracranial hemorrhage, and traumatic brain injury. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 31 1, 17-35Lu, Xi-Chun May; Hartings, Jed A; Si, Yuanzheng; Balbir, Alexander; Cao, Ying; Tortella, Frank C 2011. Electrocortical pathology in a rat model of penetrating ballistic-like brain injury. Journal of neurotrauma, 28 1, 71-83Eriksen, N; Rostrup, E; Andersen, K; Lauritzen, M J; Fabricius, M; Larsen, V A; Dreier, J P; Strong, A J; Hartings, J A; Pakkenberg, B 2010. Application of stereological estimates in patients with severe head injuries using CT and MR scanning images. The British journal of radiology, 83 988, 307-17Oliveira-Ferreira, Ana I; Milakara, Denny; Alam, Mesbah; Jorks, Devi; Major, Sebastian; Hartings, Jed A; Lückl, Janos; Martus, Peter; Graf, Rudolf; Dohmen, Christian; Bohner, Georg; Woitzik, Johannes; Dreier, Jens P 2010. Experimental and preliminary clinical evidence of an ischemic zone with prolonged negative DC shifts surrounded by a normally perfused tissue belt with persistent electrocorticographic depression. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 30 8, 1504-19Dreier, Jens P; Major, Sebastian; Manning, Andrew; Woitzik, Johannes; Drenckhahn, Chistoph; Steinbrink, Jens; Tolias, Christos; Oliveira-Ferreira, Ana I; Fabricius, Martin; Hartings, Jed A; Vajkoczy, Peter; Lauritzen, Martin; Dirnagl, Ulrich; Bohner, Georg; Strong, Anthony J 2009. Cortical spreading ischaemia is a novel process involved in ischaemic damage in patients with aneurysmal subarachnoid haemorrhage. Brain : a journal of neurology, 132 Pt 7, 1866-81Hartings, Jed A; Strong, Anthony J; Fabricius, Martin; Manning, Andrew; Bhatia, Robin; Dreier, Jens P; Mazzeo, Anna Teresa; Tortella, Frank C; Bullock, M Ross 2009. Spreading depolarizations and late secondary insults after traumatic brain injury. Journal of neurotrauma, 26 11, 1857-66Hartings, Jed A; Watanabe, Tomas; Dreier, Jens P; Major, Sebastian; Vendelbo, Leif; Fabricius, Martin 2009. Recovery of slow potentials in AC-coupled electrocorticography: application to spreading depolarizations in rat and human cerebral cortex. Journal of neurophysiology, 102 4, 2563-75Lu, Xi-Chun M; Si, Yuanzheng; Williams, Anthony J; Hartings, Jed A; Gryder, Divina; Tortella, Frank C 2009. NNZ-2566, a glypromate analog, attenuates brain ischemia-induced non-convulsive seizures in rats. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 29 12, 1924-32Fabricius, Martin; Fuhr, Susanne; Willumsen, Lisette; Dreier, Jens P; Bhatia, Robin; Boutelle, Martyn G; Hartings, Jed A; Bullock, Ross; Strong, Anthony J; Lauritzen, Martin 2008. Association of seizures with cortical spreading depression and peri-infarct depolarisations in the acutely injured human brain. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 119 9, 1973-84Hartings, Jed A; Gugliotta, Marinella; Gilman, Charlotte; Strong, Anthony J; Tortella, Frank C; Bullock, M Ross 2008. Repetitive cortical spreading depolarizations in a case of severe brain trauma. Neurological research, 30 8, 876-82Wei, Guo; Hartings, Jed A; Yang, Xiaofang; Tortella, Frank C; Lu, Xi-Chun M 2008. Extraluminal cooling of bilateral common carotid arteries as a method to achieve selective brain cooling for neuroprotection. Journal of neurotrauma, 25 5, 549-59Williams, Anthony J; Tortella, Frank C; Gryder, Divina; Hartings, Jed A 2008. Topiramate reduces non-convulsive seizures after focal brain ischemia in the rat. Neuroscience letters, 430 1, 7-12Strong, Anthony J; Hartings, Jed A; Dreier, Jens P 2007. Cortical spreading depression: an adverse but treatable factor in intensive care? Current opinion in critical care, 13 2, 126-33Dreier, Jens P; Woitzik, Johannes; Fabricius, Martin; Bhatia, Robin; Major, Sebastian; Drenckhahn, Chistoph; Lehmann, Thomas-Nicolas; Sarrafzadeh, Asita; Willumsen, Lisette; Hartings, Jed A; Sakowitz, Oliver W; Seemann, Jörg H; Thieme, Anja; Lauritzen, Martin; Strong, Anthony J 2006. Delayed ischaemic neurological deficits after subarachnoid haemorrhage are associated with clusters of spreading depolarizations. Brain : a journal of neurology, 129 Pt 12, 3224-37Hartings, Jed A; Tortella, Frank C; Rolli, Michael L 2006. AC electrocorticographic correlates of peri-infarct depolarizations during transient focal ischemia and reperfusion. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 26 5, 696-707Williams, Anthony J; Bautista, Charisma C; Chen, Ren-Wu; Dave, Jitendra R; Lu, Xi-Chun M; Tortella, Frank C; Hartings, Jed A 2006. Evaluation of gabapentin and ethosuximide for treatment of acute nonconvulsive seizures following ischemic brain injury in rats. The Journal of pharmacology and experimental therapeutics, 318 3, 947-55Williams, Anthony J; Hartings, Jed A; Lu, Xi-Chun M; Rolli, Michael L; Tortella, Frank C 2006. Penetrating ballistic-like brain injury in the rat: differential time courses of hemorrhage, cell death, inflammation, and remote degeneration. Journal of neurotrauma, 23 12, 1828-46Lu, X-C May; Williams, Anthony J; Wagstaff, John D; Tortella, Frank C; Hartings, Jed A 2005. Effects of delayed intrathecal infusion of an NMDA receptor antagonist on ischemic injury and peri-infarct depolarizations. Brain research, 1056 2, 200-8Williams, Anthony J; Hartings, Jed A; Lu, X-C May; Rolli, Michael L; Dave, Jitendra R; Tortella, Frank C 2005. Characterization of a new rat model of penetrating ballistic brain injury. Journal of neurotrauma, 22 2, 313-31Yao, C; Williams, A J; Hartings, J A; Lu, X-C M; Tortella, F C; Dave, J R 2005. Down-regulation of the sodium channel Na(v)1.1 alpha-subunit following focal ischemic brain injury in rats: in situ hybridization and immunohistochemical analysis. Life sciences, 77 10, 1116-29Khatri, V; Hartings, J A; Simons, D J 2004. Adaptation in thalamic barreloid and cortical barrel neurons to periodic whisker deflections varying in frequency and velocity. Journal of neurophysiology, 92 6, 3244-54Lu, X-C May; Williams, Anthony J; Yao, Changping; Berti, Rossana; Hartings, Jed A; Whipple, Rebecca; Vahey, Maryanne T; Polavarapu, Ratna G; Woller, Kimberly L; Tortella, Frank C; Dave, Jitendra R 2004. Microarray analysis of acute and delayed gene expression profile in rats after focal ischemic brain injury and reperfusion. Journal of neuroscience research, 77 6, 843-57Williams, A J; Tortella, F C; Lu, X M; Moreton, J E; Hartings, J A 2004. Antiepileptic drug treatment of nonconvulsive seizures induced by experimental focal brain ischemia. The Journal of pharmacology and experimental therapeutics, 311 1, 220-7Hartings, Jed A; Rolli, Michael L; Lu, X-C May; Tortella, Frank C 2003. Delayed secondary phase of peri-infarct depolarizations after focal cerebral ischemia: relation to infarct growth and neuroprotection. The Journal of neuroscience : the official journal of the Society for Neuroscience, 23 37, 11602-10Hartings, Jed A; Temereanca, Simona; Simons, Daniel J 2003. Processing of periodic whisker deflections by neurons in the ventroposterior medial and thalamic reticular nuclei. Journal of neurophysiology, 90 5, 3087-94Hartings, Jed A; Temereanca, Simona; Simons, Daniel J 2003. State-dependent processing of sensory stimuli by thalamic reticular neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience, 23 12, 5264-71Hartings, Jed A; Williams, Anthony J; Tortella, Frank C 2003. Occurrence of nonconvulsive seizures, periodic epileptiform discharges, and intermittent rhythmic delta activity in rat focal ischemia. Experimental neurology, 179 2, 139-49Pinto, David J; Hartings, Jed A; Brumberg, Joshua C; Simons, Daniel J 2003. Cortical damping: analysis of thalamocortical response transformations in rodent barrel cortex. Cerebral cortex (New York, N.Y. : 1991), 13 1, 33-44Williams, Anthony J; Lu, Xi-Chun M; Hartings, Jed A; Tortella, Frank C 2003. Neuroprotection assessment by topographic electroencephalographic analysis: effects of a sodium channel blocker to reduce polymorphic delta activity following ischaemic brain injury in rats. Fundamental & clinical pharmacology, 17 5, 581-93Kelly, M K; Carvell, G E; Hartings, J A; Simons, D J 2001. Axonal conduction properties of antidromically identified neurons in rat barrel cortex. Somatosensory & motor research, 18 3, 202-10Hartings, J A; Simons, D J 2000. Inhibition suppresses transmission of tonic vibrissa-evoked activity in the rat ventrobasal thalamus. The Journal of neuroscience : the official journal of the Society for Neuroscience, 20 19, RC100Hartings, J A; Temereanca, S; Simons, D J 2000. High responsiveness and direction sensitivity of neurons in the rat thalamic reticular nucleus to vibrissa deflections. Journal of neurophysiology, 83 5, 2791-801Hartings, J A; Simons, D J 1998. Thalamic relay of afferent responses to 1- to 12-Hz whisker stimulation in the rat. Journal of neurophysiology, 80 2, 1016-9Fraser, George; Hartings, Jed A; Simons, Daniel J . Adaptation of trigeminal ganglion cells to periodic whisker deflections. Somatosensory & motor research, 23 3-4, 111-8
Research InterestsAreas of expertise - pathophysiology and treatment of traumatic brain injury and stroke, with emphasis on spreading depression, seizures, and neuromonitoring
Peer Reviewed Publications Claassen, Jan; Akbari, Yama; Alexander, Sheila; Bader, Mary Kay; Bell, Kathleen; Bleck, Thomas P; Boly, Melanie; Brown, Jeremy; Chou, Sherry H-Y; Diringer, Michael N; Edlow, Brian L; Foreman, Brandon; Giacino, Joseph T; Gosseries, Olivia; Green, Theresa; Greer, David M; Hanley, Daniel F; Hartings, Jed A; Helbok, Raimund; Hemphill, J Claude; Hinson, H E; Hirsch, Karen; Human, Theresa; James, Michael L; Ko, Nerissa; Kondziella, Daniel; Livesay, Sarah; Madden, Lori K; Mainali, Shraddha; Mayer, Stephan A; McCredie, Victoria; McNett, Molly M; Meyfroidt, Geert; Monti, Martin M; Muehlschlegel, Susanne; Murthy, Santosh; Nyquist, Paul; Olson, DaiWai M; Provencio, J Javier; Rosenthal, Eric; Sampaio Silva, Gisele; Sarasso, Simone; Schiff, Nicholas D; Sharshar, Tarek; Shutter, Lori; Stevens, Robert D; Vespa, Paul; Videtta, Walter; Wagner, Amy; Ziai, Wendy; Whyte, John; Zink, Elizabeth; Suarez, Jose I 2021. Proceedings of the First Curing Coma Campaign NIH Symposium: Challenging the Future of Research for Coma and Disorders of Consciousness. Neurocritical care, 35 Suppl 1, 4-23Foreman, Brandon; Lee, Hyunjo; Mizrahi, Moshe A; Hartings, Jed A; Ngwenya, Laura B; Privitera, Michael; Tortella, Frank C; Zhang, Nanhua; Kramer, Joel H 2021. Seizures and Cognitive Outcome After Traumatic Brain Injury: A Post Hoc Analysis. Neurocritical care, , Hartings, Jed A; Carroll, Christopher P; Lee, Gregory 2021. Spreading Diffusion-Restriction Events in the Gyrencephalic Brain After Subarachnoid Hemorrhage Revealed by Continuous Magnetic Resonance Imaging. Neurocritical care, , Jewell, Sharon; Hobson, Stephen; Brewer, Grant; Rogers, Michelle; Hartings, Jed A; Foreman, Brandon; Lavrador, José-Pedro; Sole, Michael; Pahl, Clemens; Boutelle, Martyn G; Strong, Anthony J 2021. Development and Evaluation of a Method for Automated Detection of Spreading Depolarizations in the Injured Human Brain. Neurocritical care, 35 Suppl 2, 160-175Barhorst, Kinsey A; Alfawares, Yara; McGuire, Jennifer L; Danzer, Steve C; Hartings, Jed A; Ngwenya, Laura B 2020. Remote and Persistent Alterations in Glutamate Receptor Subunit Composition Induced by Spreading Depolarizations in Rat Brain. Cellular and molecular neurobiology, , Hartings, Jed A; Andaluz, Norberto; Bullock, M Ross; Hinzman, Jason M; Mathern, Bruce; Pahl, Clemens; Puccio, Ava; Shutter, Lori A; Strong, Anthony J; Vagal, Achala; Wilson, J Adam; Dreier, Jens P; Ngwenya, Laura B; Foreman, Brandon; Pahren, Laura; Lingsma, Hester; Okonkwo, David O 2020. Prognostic Value of Spreading Depolarizations in Patients With Severe Traumatic Brain Injury. JAMA neurology, 77 4, 489-499Helbok, Raimund; Hartings, Jed A; Schiefecker, Alois; Balança, Baptiste; Jewel, Sharon; Foreman, Brandon; Ercole, Ari; Balu, Ramani; Ayata, Cenk; Ngwenya, Laura; Rosenthal, Eric; Boutelle, Martyn G; Farkas, Eszter; Dreier, Jens P; Fabricius, Martin; Shuttleworth, C William; Carlson, Andrew 2020. What Should a Clinician Do When Spreading Depolarizations are Observed in a Patient? Neurocritical care, 32 1, 306-310Provencio, J Javier; Hemphill, J Claude; Claassen, Jan; Edlow, Brian L; Helbok, Raimund; Vespa, Paul M; Diringer, Michael N; Polizzotto, Len; Shutter, Lori; Suarez, Jose I; Stevens, Robert D; Hanley, Daniel F; Akbari, Yama; Bleck, Thomas P; Boly, Melanie; Foreman, Brandon; Giacino, Joseph T; Hartings, Jed A; Human, Theresa; Kondziella, Daniel; Ling, Geoffrey S F; Mayer, Stephan A; McNett, Molly; Menon, David K; Meyfroidt, Geert; Monti, Martin M; Park, Soojin; Pouratian, Nader; Puybasset, Louis; Rohaut, Benjamin; Rosenthal, Eric S; Schiff, Nicholas D; Sharshar, Tarek; Wagner, Amy; Whyte, John; Olson, DaiWai M 2020. The Curing Coma Campaign: Framing Initial Scientific Challenges-Proceedings of the First Curing Coma Campaign Scientific Advisory Council Meeting. Neurocritical care, 33 1, 1-12Shuttleworth, C William; Andrew, R David; Akbari, Yama; Ayata, Cenk; Balu, Ramani; Brennan, K C; Boutelle, Martyn; Carlson, Andrew P; Dreier, Jens P; Fabricius, Martin; Farkas, Eszter; Foreman, Brandon; Helbok, Raimund; Henninger, Nils; Jewell, Sharon L; Jones, Stephen C; Kirov, Sergei A; Lindquist, Britta E; Maciel, Carolina B; Okonkwo, David; Reinhart, Katelyn M; Robertson, R Meldrum; Rosenthal, Eric S; Watanabe, Tomas; Hartings, Jed A 2020. Which Spreading Depolarizations Are Deleterious To Brain Tissue? Neurocritical care, 32 1, 317-322Dreier, Jens P; Major, Sebastian; Lemale, Coline L; Kola, Vasilis; Reiffurth, Clemens; Schoknecht, Karl; Hecht, Nils; Hartings, Jed A; Woitzik, Johannes 2019. Correlates of Spreading Depolarization, Spreading Depression, and Negative Ultraslow Potential in Epidural Versus Subdural Electrocorticography. Frontiers in neuroscience, 13 , 373Eriksen, Nina; Pakkenberg, Bente; Rostrup, Egill; Okonkwo, David O; Mathern, Bruce; Shutter, Lori A; Strong, Anthony J; Woitzik, Johannes; Pahl, Clemens; Dreier, Jens P; Martus, Peter; Lauritzen, Martin J; Fabricius, Martin; Hartings, Jed A 2019. Neurostereologic Lesion Volumes and Spreading Depolarizations in Severe Traumatic Brain Injury Patients: A Pilot Study. Neurocritical care, 30 3, 557-568Eriksen, Nina; Rostrup, Egill; Fabricius, Martin; Scheel, Michael; Major, Sebastian; Winkler, Maren K L; Bohner, Georg; Santos, Edgar; Sakowitz, Oliver W; Kola, Vasilis; Reiffurth, Clemens; Hartings, Jed A; Vajkoczy, Peter; Woitzik, Johannes; Martus, Peter; Lauritzen, Martin; Pakkenberg, Bente; Dreier, Jens P 2019. Early focal brain injury after subarachnoid hemorrhage correlates with spreading depolarizations. Neurology, 92 4, e326-e341Hartings, Jed A 2019. How slow can you go? Nature materials, 18 3, 194-196Lee, Hyunjo; Mizrahi, Moshe A; Hartings, Jed A; Sharma, Sameer; Pahren, Laura; Ngwenya, Laura B; Moseley, Brian D; Privitera, Michael; Tortella, Frank C; Foreman, Brandon 2019. Continuous Electroencephalography After Moderate to Severe Traumatic Brain Injury. Critical care medicine, 47 4, 574-582Santos, Edgar; Olivares-Rivera, Arturo; Major, Sebastian; Sánchez-Porras, Renán; Uhlmann, Lorenz; Kunzmann, Kevin; Zerelles, Roland; Kentar, Modar; Kola, Vasilis; Aguilera, Adrian Hernández; Herrera, Mildred Gutierrez; Lemale, Coline L; Woitzik, Johannes; Hartings, Jed A; Sakowitz, Oliver W; Unterberg, Andreas W; Dreier, Jens P 2019. Lasting s-ketamine block of spreading depolarizations in subarachnoid hemorrhage: a retrospective cohort study. Critical care (London, England), 23 1, 427Carlson, Andrew P; Shuttleworth, C William; Major, Sebastian; Lemale, Coline L; Dreier, Jens P; Hartings, Jed A 2018. Terminal spreading depolarizations causing electrocortical silencing prior to clinical brain death: case report. Journal of neurosurgery, 131 6, 1773-1779Dreier, Jens P; Major, Sebastian; Foreman, Brandon; Winkler, Maren K L; Kang, Eun-Jeung; Milakara, Denny; Lemale, Coline L; DiNapoli, Vince; Hinzman, Jason M; Woitzik, Johannes; Andaluz, Norberto; Carlson, Andrew; Hartings, Jed A 2018. Terminal spreading depolarization and electrical silence in death of human cerebral cortex. Annals of neurology, 83 2, 295-310Foreman, Brandon; Ngwenya, Laura B; Stoddard, Erica; Hinzman, Jason M; Andaluz, Norberto; Hartings, Jed A 2018. Safety and Reliability of Bedside, Single Burr Hole Technique for Intracranial Multimodality Monitoring in Severe Traumatic Brain Injury. Neurocritical care, 29 3, 469-480Hartings, Jed A; Ngwenya, Laura B; Carroll, Christopher P; Foreman, Brandon 2018. Letter to the Editor. Ketamine sedation for the suppression of spreading depolarizations. Journal of neurosurgery, , 1-2Hartings, Jed A; Ngwenya, Laura B; Watanabe, Tomas; Foreman, Brandon 2018. Commentary: Detecting Cortical Spreading Depolarization with Full Band Scalp Electroencephalography: An Illusion? Frontiers in systems neuroscience, 12 , 19Lückl, Janos; Lemale, Coline L; Kola, Vasilis; Horst, Viktor; Khojasteh, Uldus; Oliveira-Ferreira, Ana I; Major, Sebastian; Winkler, Maren K L; Kang, Eun-Jeung; Schoknecht, Karl; Martus, Peter; Hartings, Jed A; Woitzik, Johannes; Dreier, Jens P 2018. The negative ultraslow potential, electrophysiological correlate of infarction in the human cortex. Brain : a journal of neurology, 141 6, 1734-1752Schinke, Christian; Horst, Viktor; Schlemm, Ludwig; Wawra, Matthias; Scheel, Michael; Hartings, Jed A; Dreier, Jens P 2018. A case report of delayed cortical infarction adjacent to sulcal clots after traumatic subarachnoid hemorrhage in the absence of proximal vasospasm. BMC neurology, 18 1, 210Cnossen, Maryse C; Huijben, Jilske A; van der Jagt, Mathieu; Volovici, Victor; van Essen, Thomas; Polinder, Suzanne; Nelson, David; Ercole, Ari; Stocchetti, Nino; Citerio, Giuseppe; Peul, Wilco C; Maas, Andrew I R; Menon, David; Steyerberg, Ewout W; Lingsma, Hester F 2017. Variation in monitoring and treatment policies for intracranial hypertension in traumatic brain injury: a survey in 66 neurotrauma centers participating in the CENTER-TBI study. Critical care (London, England), 21 1, 233Hartings JA 2017. Spreading depolarization monitoring in neurocritical care of acute brain injury Current Opinion in Critical Care, 23 2, 94Hartings, Jed A 2017. Spreading depolarization monitoring in neurocritical care of acute brain injury. Current opinion in critical care, 23 2, 94-102Hartings, Jed A; Dreier, Jens P 2017. Real-time detection of lesion development in acute brain injury. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 37 5, 1550-1552Hartings, Jed A; York, Jonathan; Carroll, Christopher P; Hinzman, Jason M; Mahoney, Eric; Krueger, Bryan; Winkler, Maren K L; Major, Sebastian; Horst, Viktor; Jahnke, Paul; Woitzik, Johannes; Kola, Vasilis; Du, Yifeng; Hagen, Matthew; Jiang, Jianxiong; Dreier, Jens P 2017. Subarachnoid blood acutely induces spreading depolarizations and early cortical infarction. Brain : a journal of neurology, 140 10, 2673-2690Maas, Andrew I R; Menon, David K; Adelson, P David; Andelic, Nada; Bell, Michael J; Belli, Antonio; Bragge, Peter; Brazinova, Alexandra; Büki, András; Chesnut, Randall M; Citerio, Giuseppe; Coburn, Mark; Cooper, D Jamie; Crowder, A Tamara; Czeiter, Endre; Czosnyka, Marek; Diaz-Arrastia, Ramon; Dreier, Jens P; Duhaime, Ann-Christine; Ercole, Ari; van Essen, Thomas A; Feigin, Valery L; Gao, Guoyi; Giacino, Joseph; Gonzalez-Lara, Laura E; Gruen, Russell L; Gupta, Deepak; Hartings, Jed A; Hill, Sean; Jiang, Ji-Yao; Ketharanathan, Naomi; Kompanje, Erwin J O; Lanyon, Linda; Laureys, Steven; Lecky, Fiona; Levin, Harvey; Lingsma, Hester F; Maegele, Marc; Majdan, Marek; Manley, Geoffrey; Marsteller, Jill; Mascia, Luciana; McFadyen, Charles; Mondello, Stefania; Newcombe, Virginia; Palotie, Aarno; Parizel, Paul M; Peul, Wilco; Piercy, James; Polinder, Suzanne; Puybasset, Louis; Rasmussen, Todd E; Rossaint, Rolf; Smielewski, Peter; Söderberg, Jeannette; Stanworth, Simon J; Stein, Murray B; von Steinbüchel, Nicole; Stewart, William; Steyerberg, Ewout W; Stocchetti, Nino; Synnot, Anneliese; Te Ao, Braden; Tenovuo, Olli; Theadom, Alice; Tibboel, Dick; Videtta, Walter; Wang, Kevin K W; Williams, W Huw; Wilson, Lindsay; Yaffe, Kristine 2017. Traumatic brain injury: integrated approaches to improve prevention, clinical care, and research. The Lancet. Neurology, 16 12, 987-1048Milakara, Denny; Grozea, Cristian; Dahlem, Markus; Major, Sebastian; Winkler, Maren K L; Lückl, Janos; Scheel, Michael; Kola, Vasilis; Schoknecht, Karl; Lublinsky, Svetlana; Friedman, Alon; Martus, Peter; Hartings, Jed A; Woitzik, Johannes; Dreier, Jens P 2017. Simulation of spreading depolarization trajectories in cerebral cortex: Correlation of velocity and susceptibility in patients with aneurysmal subarachnoid hemorrhage. NeuroImage. Clinical, 16 , 524-538Pinczolits A, Zdunczyk A, Dengler NF, Hecht N, Kowoll CM, Dohmen C, Graf R, Winkler MK, Major S, Hartings JA, Dreier JP, Vajkoczy P, Woitzik J. 2017. Standard-sampling microdialysis and spreading depolarizations in patients with malignant hemispheric stroke Journal of Cerebral Blood Flow and Metabolism , 37 5, 1896Pinczolits, Alexandra; Zdunczyk, Anna; Dengler, Nora F; Hecht, Nils; Kowoll, Christina M; Dohmen, Christian; Graf, Rudolf; Winkler, Maren Kl; Major, Sebastian; Hartings, Jed A; Dreier, Jens P; Vajkoczy, Peter; Woitzik, Johannes 2017. Standard-sampling microdialysis and spreading depolarizations in patients with malignant hemispheric stroke. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 37 5, 1896-19055. Wu Z, Li C, Hartings JA, Narayan R, Ahn C 2016. Polysilicon thin film developed on flexible polyimide for biomedical applications . IEEE Journal of Microelectromechanical Systems , 25 4, 585Bogdanov, Volodymyr B; Middleton, Natalie A; Theriot, Jeremy J; Parker, Patrick D; Abdullah, Osama M; Ju, Y Sungtaek; Hartings, Jed A; Brennan, K C 2016. Susceptibility of Primary Sensory Cortex to Spreading Depolarizations. The Journal of neuroscience : the official journal of the Society for Neuroscience, 36 17, 4733-43Dreier, Jens P; Fabricius, Martin; Ayata, Cenk; Sakowitz, Oliver W; William Shuttleworth, C; Dohmen, Christian; Graf, Rudolf; Vajkoczy, Peter; Helbok, Raimund; Suzuki, Michiyasu; Schiefecker, Alois J; Major, Sebastian; Winkler, Maren Kl; Kang, Eun-Jeung; Milakara, Denny; Oliveira-Ferreira, Ana I; Reiffurth, Clemens; Revankar, Gajanan S; Sugimoto, Kazutaka; Dengler, Nora F; Hecht, Nils; Foreman, Brandon; Feyen, Bart; Kondziella, Daniel; Friberg, Christian K; Piilgaard, Henning; Rosenthal, Eric S; Westover, M Brandon; Maslarova, Anna; Santos, Edgar; Hertle, Daniel; Sánchez-Porras, Renán; Jewell, Sharon L; Balança, Baptiste; Platz, Johannes; Hinzman, Jason M; Lückl, Janos; Schoknecht, Karl; Schöll, Michael; Drenckhahn, Christoph; Feuerstein, Delphine; Eriksen, Nina; Horst, Viktor; Bretz, Julia S; Jahnke, Paul; Scheel, Michael; Bohner, Georg; Rostrup, Egill; Pakkenberg, Bente; Heinemann, Uwe; Claassen, Jan; Carlson, Andrew P; Kowoll, Christina M; Lublinsky, Svetlana; Chassidim, Yoash; Shelef, Ilan; Friedman, Alon; Brinker, Gerrit; Reiner, Michael; Kirov, Sergei A; Andrew, R David; Farkas, Eszter; Güresir, Erdem; Vatter, Hartmut; Chung, Lee S; Brennan, K C; Lieutaud, Thomas; Marinesco, Stephane; Maas, Andrew Ir; Sahuquillo, Juan; Dahlem, Markus A; Richter, Frank; Herreras, Oscar; Boutelle, Martyn G; Okonkwo, David O; Bullock, M Ross; Witte, Otto W; Martus, Peter; van den Maagdenberg, Arn Mjm; Ferrari, Michel D; Dijkhuizen, Rick M; Shutter, Lori A; Andaluz, Norberto; Schulte, André P; MacVicar, Brian; Watanabe, Tomas; Woitzik, Johannes; Lauritzen, Martin; Strong, Anthony J; Hartings, Jed A 2016. Recording, analysis, and interpretation of spreading depolarizations in neurointensive care: Review and recommendations of the COSBID research group. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, , Drenckhahn, Christoph; Windler, Claudia; Major, Sebastian; Kang, Eun-Jeung; Scheel, Michael; Vajkoczy, Peter; Hartings, Jed A; Woitzik, Johannes; Dreier, Jens P 2016. Complications in Aneurysmal Subarachnoid Hemorrhage Patients With and Without Subdural Electrode Strip for Electrocorticography. Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society, 33 3, 250-9Hartings, Jed A; Li, Chunyan; Hinzman, Jason M; Shuttleworth, C William; Ernst, Griffin L; Dreier, Jens P; Wilson, J Adam; Andaluz, Norberto; Foreman, Brandon; Carlson, Andrew P 2016. Direct current electrocorticography for clinical neuromonitoring of spreading depolarizations. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, , Hartings, Jed A; Shuttleworth, C William; Kirov, Sergei A; Ayata, Cenk; Hinzman, Jason M; Foreman, Brandon; Andrew, R David; Boutelle, Martyn G; Brennan, K C; Carlson, Andrew P; Dahlem, Markus A; Drenckhahn, Christoph; Dohmen, Christian; Fabricius, Martin; Farkas, Eszter; Feuerstein, Delphine; Graf, Rudolf; Helbok, Raimund; Lauritzen, Martin; Major, Sebastian; Oliveira-Ferreira, Ana I; Richter, Frank; Rosenthal, Eric S; Sakowitz, Oliver W; Sánchez-Porras, Renán; Santos, Edgar; Schöll, Michael; Strong, Anthony J; Urbach, Anja; Westover, M Brandon; Winkler, Maren Kl; Witte, Otto W; Woitzik, Johannes; Dreier, Jens P 2016. The continuum of spreading depolarizations in acute cortical lesion development: Examining Leão's legacy. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, , Li, Chunyan; Narayan, Raj K; Wang, Ping; Hartings, Jed A 2016. Regional temperature and quantitative cerebral blood flow responses to cortical spreading depolarization in the rat. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, , Li, Chunyan; Narayan, Raj K; Wu, Pei-Ming; Rajan, Neena; Wu, Zhizhen; Mehan, Neal; Golanov, Eugene V; Ahn, Chong H; Hartings, Jed A 2016. Evaluation of microelectrode materials for direct-current electrocorticography. Journal of neural engineering, 13 1, 016008Li, Chunyan; Wu, Zhizhen; Limnuson, Kanokwan; Cheyuo, Cletus; Wang, Ping; Ahn, Chong H; Narayan, Raj K; Hartings, Jed A 2016. Development and application of a microfabricated multimodal neural catheter for neuroscience. Biomedical microdevices, 18 1, 8Toth, Peter; Szarka, Nikolett; Farkas, Eszter; Ezer, Erzsebet; Czeiter, Endre; Amrein, Krisztina; Ungvari, Zoltan; Hartings, Jed A; Buki, Andras; Koller, Akos 2016. Traumatic brain injury-induced autoregulatory dysfunction and spreading depression-related neurovascular uncoupling: Pathomechanisms, perspectives, and therapeutic implications. American journal of physiology. Heart and circulatory physiology, 311 5, H1118-H1131Winkler, Maren Kl; Dengler, Nora; Hecht, Nils; Hartings, Jed A; Kang, Eun J; Major, Sebastian; Martus, Peter; Vajkoczy, Peter; Woitzik, Johannes; Dreier, Jens P 2016. Oxygen availability and spreading depolarizations provide complementary prognostic information in neuromonitoring of aneurysmal subarachnoid hemorrhage patients. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, , Wu Z, Li C, Hartings JA, Narayan RK, Ahn C 2016. Polysilicon based flexible temperature sensor for high resolution brain temperature monitoring . Conf Proc IEEE Eng Med Biol Soc , , 500Hinzman, Jason M; DiNapoli, Vince A; Mahoney, Eric J; Gerhardt, Greg A; Hartings, Jed A 2015. Spreading depolarizations mediate excitotoxicity in the development of acute cortical lesions. Experimental neurology, 267 , 243-53Hinzman, Jason M; Gibson, Justin L; Tackla, Ryan D; Costello, Mark S; Burmeister, Jason J; Quintero, Jorge E; Gerhardt, Greg A; Hartings, Jed A 2015. Real-time monitoring of extracellular adenosine using enzyme-linked microelectrode arrays. Biosensors & bioelectronics, 74 , 512-517Hinzman, Jason; Wilson, J Adam; Mazzeo, Anna Teresa; Bullock, Ross; Hartings, Jed A 2015. Excitotoxicity and Metabolic Crisis Are Associated with Spreading Depolarizations in Severe Traumatic Brain Injury Patients. Journal of neurotrauma, , Li, Chunyan; Limnuson, Kanokwan; Wu, Zhizhen; Amin, Aseer; Narayan, Anjali; Golanov, Eugene V; Ahn, Chong H; Hartings, Jed A; Narayan, Raj K 2015. Single probe for real-time simultaneous monitoring of neurochemistry and direct-current electrocorticography. Biosensors & bioelectronics, 77 , 62-68Li, Chunyan; Wu, Pei-Ming; Wu, Zhizhen; Limnuson, Kanokwan; Mehan, Neal; Mozayan, Cameron; Golanov, Eugene V; Ahn, Chong H; Hartings, Jed A; Narayan, Raj K 2015. Highly accurate thermal flow microsensor for continuous and quantitative measurement of cerebral blood flow. Biomedical microdevices, 17 5, 9992Maas, Andrew I R; Menon, David K; Steyerberg, Ewout W; Citerio, Giuseppe; Lecky, Fiona; Manley, Geoffrey T; Hill, Sean; Legrand, Valerie; Sorgner, Annina 2015. Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI): a prospective longitudinal observational study. Neurosurgery, 76 1, 67-80Tackla, Ryan; Hinzman, Jason M; Foreman, Brandon; Magner, Mark; Andaluz, Norberto; Hartings, Jed A 2015. Assessment of Cerebrovascular Autoregulation Using Regional Cerebral Blood Flow in Surgically Managed Brain Trauma Patients. Neurocritical care, , Jeffcote, Toby; Hinzman, Jason M; Jewell, Sharon L; Learney, Robert M; Pahl, Clemens; Tolias, Christos; Walsh, Daniel C; Hocker, Sara; Zakrzewska, Agnieszka; Fabricius, Martin E; Strong, Anthony J; Hartings, Jed A; Boutelle, Martyn G 2014. Detection of spreading depolarization with intraparenchymal electrodes in the injured human brain. Neurocritical care, 20 1, 21-31Dreier, Jens P; Drenckhahn, Christoph; Woitzik, Johannes; Major, Sebastian; Offenhauser, Nikolas; Weber-Carstens, Steffen; Wolf, Stefan; Strong, Anthony J; Vajkoczy, Peter; Hartings, Jed A 2013. Spreading Ischemia After Aneurysmal Subarachnoid Hemorrhage. Acta neurochirurgica. Supplement, 115 , 125-129Hartings, Jed A; Vidgeon, Steven; Strong, Anthony J; Zacko, Chris; Vagal, Achala; Andaluz, Norberto; Ridder, Thomas; Stanger, Richard; Fabricius, Martin; Mathern, Bruce; Pahl, Clemens; Tolias, Christos M; Bullock, M Ross 2013. Surgical management of traumatic brain injury: a comparative-effectiveness study of 2 centers. Journal of neurosurgery, , Hartings, Jed A; Wilson, J Adam; Look, Andrew C; Vagal, Achala; Shutter, Lori A; Dreier, Jens P; Ringer, Andrew; Zuccarello, Mario 2013. Full-band electrocorticography of spreading depolarizations in patients with aneurysmal subarachnoid hemorrhage. Acta neurochirurgica. Supplement, 115 , 131-41Serrone, Joseph C; Wash, Erin M; Hartings, Jed A; Andaluz, Norberto; Zuccarello, Mario 2013. Venous Thromboembolism in Subarachnoid Hemorrhage. World neurosurgery, , Wilson, J Adam; Shutter, Lori A; Hartings, Jed A 2013. COSBID-M3: A Platform for Multimodal Monitoring, Data Collection, and Research in Neurocritical Care. Acta neurochirurgica. Supplement, 115 , 67-74Dreier, Jens P; Major, Sebastian; Pannek, Heinz-Wolfgang; Woitzik, Johannes; Scheel, Michael; Wiesenthal, Dirk; Martus, Peter; Winkler, Maren K L; Hartings, Jed A; Fabricius, Martin; Speckmann, Erwin-Josef; Gorji, Ali 2012. Spreading convulsions, spreading depolarization and epileptogenesis in human cerebral cortex. Brain : a journal of neurology, 135 Pt 1, 259-75Drenckhahn, Christoph; Winkler, Maren K L; Major, Sebastian; Scheel, Michael; Kang, Eun-Jeung; Pinczolits, Alexandra; Grozea, Cristian; Hartings, Jed A; Woitzik, Johannes; Dreier, Jens P 2012. Correlates of spreading depolarization in human scalp electroencephalography. Brain : a journal of neurology, 135 Pt 3, 853-68Hertle, Daniel N; Dreier, Jens P; Woitzik, Johannes; Hartings, Jed A; Bullock, Ross; Okonkwo, David O; Shutter, Lori A; Vidgeon, Steven; Strong, Anthony J; Kowoll, Christina; Dohmen, Christian; Diedler, Jennifer; Veltkamp, Roland; Bruckner, Thomas; Unterberg, Andreas W; Sakowitz, Oliver W 2012. Effect of analgesics and sedatives on the occurrence of spreading depolarizations accompanying acute brain injury. Brain : a journal of neurology, 135 Pt 8, 2390-2398Li, Chunyan; Wu, Pei-Ming; Hartings, Jed A; Wu, Zhizhen; Cheyuo, Cletus; Wang, Ping; Ledoux, David; Shutter, Lori A; Ramaswamy, Bharat Ram; Ahn, Chong H; Narayan, Raj K 2012. Micromachined lab-on-a-tube sensors for simultaneous brain temperature and cerebral blood flow measurements. Biomedical microdevices, , Li, Chunyan; Wu, Pei-Ming; Wu, Zhizhen; Ahn, Chong H; LeDoux, David; Shutter, Lori A; Hartings, Jed A; Narayan, Raj K 2012. Brain temperature measurement: A study of in vitro accuracy and stability of smart catheter temperature sensors. Biomedical microdevices, 14 1, 109-18Li, Chunyan; Wu, Zhizhen; Hartings, Jed A; Rajan, Neena; Chahine, Nadeen; Cheyuo, Cletus; Wang, Ping; Wu, Pei-Ming; Golanov, Eugene V; Ahn, Chong H; Narayan, Raj K 2012. Brain-friendly amperometric enzyme biosensor based on encapsulated oxygen generating biomaterial. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference, 2012 , 6003-6Fioravanti, Beatriz; Kasasbeh, Aimen; Edelmayer, Rebecca; Skinner, David P; Hartings, Jed A; Burklund, Ryan D; De Felice, Milena; French, Edward D; Dussor, Greg O; Dodick, David W; Porreca, Frank; Vanderah, Todd W 2011. Evaluation of cutaneous allodynia following induction of cortical spreading depression in freely moving rats. Cephalalgia : an international journal of headache, 31 10, 1090-100Hartings, Jed A; Bullock, M Ross; Okonkwo, David O; Murray, Lilian S; Murray, Gordon D; Fabricius, Martin; Maas, Andrew Ir; Woitzik, Johannes; Sakowitz, Oliver; Mathern, Bruce; Roozenbeek, Bob; Lingsma, Hester; Dreier, Jens P; Puccio, Ava M; Shutter, Lori A; Pahl, Clemens; Strong, Anthony J 2011. Spreading depolarisations and outcome after traumatic brain injury: a prospective observational study. Lancet neurology, 10 12, 1058-64Hartings, Jed A; Watanabe, Tomas; Bullock, M Ross; Okonkwo, David O; Fabricius, Martin; Woitzik, Johannes; Dreier, Jens P; Puccio, Ava; Shutter, Lori A; Pahl, Clemens; Strong, Anthony J 2011. Spreading depolarizations have prolonged direct current shifts and are associated with poor outcome in brain trauma. Brain : a journal of neurology, 134 Pt 5, 1529-40Lauritzen, Martin; Dreier, Jens Peter; Fabricius, Martin; Hartings, Jed A; Graf, Rudolf; Strong, Anthony John 2011. Clinical relevance of cortical spreading depression in neurological disorders: migraine, malignant stroke, subarachnoid and intracranial hemorrhage, and traumatic brain injury. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 31 1, 17-35Lu, Xi-Chun May; Hartings, Jed A; Si, Yuanzheng; Balbir, Alexander; Cao, Ying; Tortella, Frank C 2011. Electrocortical pathology in a rat model of penetrating ballistic-like brain injury. Journal of neurotrauma, 28 1, 71-83Eriksen, N; Rostrup, E; Andersen, K; Lauritzen, M J; Fabricius, M; Larsen, V A; Dreier, J P; Strong, A J; Hartings, J A; Pakkenberg, B 2010. Application of stereological estimates in patients with severe head injuries using CT and MR scanning images. The British journal of radiology, 83 988, 307-17Oliveira-Ferreira, Ana I; Milakara, Denny; Alam, Mesbah; Jorks, Devi; Major, Sebastian; Hartings, Jed A; Lückl, Janos; Martus, Peter; Graf, Rudolf; Dohmen, Christian; Bohner, Georg; Woitzik, Johannes; Dreier, Jens P 2010. Experimental and preliminary clinical evidence of an ischemic zone with prolonged negative DC shifts surrounded by a normally perfused tissue belt with persistent electrocorticographic depression. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 30 8, 1504-19Dreier, Jens P; Major, Sebastian; Manning, Andrew; Woitzik, Johannes; Drenckhahn, Chistoph; Steinbrink, Jens; Tolias, Christos; Oliveira-Ferreira, Ana I; Fabricius, Martin; Hartings, Jed A; Vajkoczy, Peter; Lauritzen, Martin; Dirnagl, Ulrich; Bohner, Georg; Strong, Anthony J 2009. Cortical spreading ischaemia is a novel process involved in ischaemic damage in patients with aneurysmal subarachnoid haemorrhage. Brain : a journal of neurology, 132 Pt 7, 1866-81Hartings, Jed A; Strong, Anthony J; Fabricius, Martin; Manning, Andrew; Bhatia, Robin; Dreier, Jens P; Mazzeo, Anna Teresa; Tortella, Frank C; Bullock, M Ross 2009. Spreading depolarizations and late secondary insults after traumatic brain injury. Journal of neurotrauma, 26 11, 1857-66Hartings, Jed A; Watanabe, Tomas; Dreier, Jens P; Major, Sebastian; Vendelbo, Leif; Fabricius, Martin 2009. Recovery of slow potentials in AC-coupled electrocorticography: application to spreading depolarizations in rat and human cerebral cortex. Journal of neurophysiology, 102 4, 2563-75Lu, Xi-Chun M; Si, Yuanzheng; Williams, Anthony J; Hartings, Jed A; Gryder, Divina; Tortella, Frank C 2009. NNZ-2566, a glypromate analog, attenuates brain ischemia-induced non-convulsive seizures in rats. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 29 12, 1924-32Fabricius, Martin; Fuhr, Susanne; Willumsen, Lisette; Dreier, Jens P; Bhatia, Robin; Boutelle, Martyn G; Hartings, Jed A; Bullock, Ross; Strong, Anthony J; Lauritzen, Martin 2008. Association of seizures with cortical spreading depression and peri-infarct depolarisations in the acutely injured human brain. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 119 9, 1973-84Hartings, Jed A; Gugliotta, Marinella; Gilman, Charlotte; Strong, Anthony J; Tortella, Frank C; Bullock, M Ross 2008. Repetitive cortical spreading depolarizations in a case of severe brain trauma. Neurological research, 30 8, 876-82Wei, Guo; Hartings, Jed A; Yang, Xiaofang; Tortella, Frank C; Lu, Xi-Chun M 2008. Extraluminal cooling of bilateral common carotid arteries as a method to achieve selective brain cooling for neuroprotection. Journal of neurotrauma, 25 5, 549-59Williams, Anthony J; Tortella, Frank C; Gryder, Divina; Hartings, Jed A 2008. Topiramate reduces non-convulsive seizures after focal brain ischemia in the rat. Neuroscience letters, 430 1, 7-12Strong, Anthony J; Hartings, Jed A; Dreier, Jens P 2007. Cortical spreading depression: an adverse but treatable factor in intensive care? Current opinion in critical care, 13 2, 126-33Dreier, Jens P; Woitzik, Johannes; Fabricius, Martin; Bhatia, Robin; Major, Sebastian; Drenckhahn, Chistoph; Lehmann, Thomas-Nicolas; Sarrafzadeh, Asita; Willumsen, Lisette; Hartings, Jed A; Sakowitz, Oliver W; Seemann, Jörg H; Thieme, Anja; Lauritzen, Martin; Strong, Anthony J 2006. Delayed ischaemic neurological deficits after subarachnoid haemorrhage are associated with clusters of spreading depolarizations. Brain : a journal of neurology, 129 Pt 12, 3224-37Hartings, Jed A; Tortella, Frank C; Rolli, Michael L 2006. AC electrocorticographic correlates of peri-infarct depolarizations during transient focal ischemia and reperfusion. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 26 5, 696-707Williams, Anthony J; Bautista, Charisma C; Chen, Ren-Wu; Dave, Jitendra R; Lu, Xi-Chun M; Tortella, Frank C; Hartings, Jed A 2006. Evaluation of gabapentin and ethosuximide for treatment of acute nonconvulsive seizures following ischemic brain injury in rats. The Journal of pharmacology and experimental therapeutics, 318 3, 947-55Williams, Anthony J; Hartings, Jed A; Lu, Xi-Chun M; Rolli, Michael L; Tortella, Frank C 2006. Penetrating ballistic-like brain injury in the rat: differential time courses of hemorrhage, cell death, inflammation, and remote degeneration. Journal of neurotrauma, 23 12, 1828-46Lu, X-C May; Williams, Anthony J; Wagstaff, John D; Tortella, Frank C; Hartings, Jed A 2005. Effects of delayed intrathecal infusion of an NMDA receptor antagonist on ischemic injury and peri-infarct depolarizations. Brain research, 1056 2, 200-8Williams, Anthony J; Hartings, Jed A; Lu, X-C May; Rolli, Michael L; Dave, Jitendra R; Tortella, Frank C 2005. Characterization of a new rat model of penetrating ballistic brain injury. Journal of neurotrauma, 22 2, 313-31Yao, C; Williams, A J; Hartings, J A; Lu, X-C M; Tortella, F C; Dave, J R 2005. Down-regulation of the sodium channel Na(v)1.1 alpha-subunit following focal ischemic brain injury in rats: in situ hybridization and immunohistochemical analysis. Life sciences, 77 10, 1116-29Khatri, V; Hartings, J A; Simons, D J 2004. Adaptation in thalamic barreloid and cortical barrel neurons to periodic whisker deflections varying in frequency and velocity. Journal of neurophysiology, 92 6, 3244-54Lu, X-C May; Williams, Anthony J; Yao, Changping; Berti, Rossana; Hartings, Jed A; Whipple, Rebecca; Vahey, Maryanne T; Polavarapu, Ratna G; Woller, Kimberly L; Tortella, Frank C; Dave, Jitendra R 2004. Microarray analysis of acute and delayed gene expression profile in rats after focal ischemic brain injury and reperfusion. Journal of neuroscience research, 77 6, 843-57Williams, A J; Tortella, F C; Lu, X M; Moreton, J E; Hartings, J A 2004. Antiepileptic drug treatment of nonconvulsive seizures induced by experimental focal brain ischemia. The Journal of pharmacology and experimental therapeutics, 311 1, 220-7Hartings, Jed A; Rolli, Michael L; Lu, X-C May; Tortella, Frank C 2003. Delayed secondary phase of peri-infarct depolarizations after focal cerebral ischemia: relation to infarct growth and neuroprotection. The Journal of neuroscience : the official journal of the Society for Neuroscience, 23 37, 11602-10Hartings, Jed A; Temereanca, Simona; Simons, Daniel J 2003. Processing of periodic whisker deflections by neurons in the ventroposterior medial and thalamic reticular nuclei. Journal of neurophysiology, 90 5, 3087-94Hartings, Jed A; Temereanca, Simona; Simons, Daniel J 2003. State-dependent processing of sensory stimuli by thalamic reticular neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience, 23 12, 5264-71Hartings, Jed A; Williams, Anthony J; Tortella, Frank C 2003. Occurrence of nonconvulsive seizures, periodic epileptiform discharges, and intermittent rhythmic delta activity in rat focal ischemia. Experimental neurology, 179 2, 139-49Pinto, David J; Hartings, Jed A; Brumberg, Joshua C; Simons, Daniel J 2003. Cortical damping: analysis of thalamocortical response transformations in rodent barrel cortex. Cerebral cortex (New York, N.Y. : 1991), 13 1, 33-44Williams, Anthony J; Lu, Xi-Chun M; Hartings, Jed A; Tortella, Frank C 2003. Neuroprotection assessment by topographic electroencephalographic analysis: effects of a sodium channel blocker to reduce polymorphic delta activity following ischaemic brain injury in rats. Fundamental & clinical pharmacology, 17 5, 581-93Kelly, M K; Carvell, G E; Hartings, J A; Simons, D J 2001. Axonal conduction properties of antidromically identified neurons in rat barrel cortex. Somatosensory & motor research, 18 3, 202-10Hartings, J A; Simons, D J 2000. Inhibition suppresses transmission of tonic vibrissa-evoked activity in the rat ventrobasal thalamus. The Journal of neuroscience : the official journal of the Society for Neuroscience, 20 19, RC100Hartings, J A; Temereanca, S; Simons, D J 2000. High responsiveness and direction sensitivity of neurons in the rat thalamic reticular nucleus to vibrissa deflections. Journal of neurophysiology, 83 5, 2791-801Hartings, J A; Simons, D J 1998. Thalamic relay of afferent responses to 1- to 12-Hz whisker stimulation in the rat. Journal of neurophysiology, 80 2, 1016-9Fraser, George; Hartings, Jed A; Simons, Daniel J . Adaptation of trigeminal ganglion cells to periodic whisker deflections. Somatosensory & motor research, 23 3-4, 111-8
Claassen, Jan; Akbari, Yama; Alexander, Sheila; Bader, Mary Kay; Bell, Kathleen; Bleck, Thomas P; Boly, Melanie; Brown, Jeremy; Chou, Sherry H-Y; Diringer, Michael N; Edlow, Brian L; Foreman, Brandon; Giacino, Joseph T; Gosseries, Olivia; Green, Theresa; Greer, David M; Hanley, Daniel F; Hartings, Jed A; Helbok, Raimund; Hemphill, J Claude; Hinson, H E; Hirsch, Karen; Human, Theresa; James, Michael L; Ko, Nerissa; Kondziella, Daniel; Livesay, Sarah; Madden, Lori K; Mainali, Shraddha; Mayer, Stephan A; McCredie, Victoria; McNett, Molly M; Meyfroidt, Geert; Monti, Martin M; Muehlschlegel, Susanne; Murthy, Santosh; Nyquist, Paul; Olson, DaiWai M; Provencio, J Javier; Rosenthal, Eric; Sampaio Silva, Gisele; Sarasso, Simone; Schiff, Nicholas D; Sharshar, Tarek; Shutter, Lori; Stevens, Robert D; Vespa, Paul; Videtta, Walter; Wagner, Amy; Ziai, Wendy; Whyte, John; Zink, Elizabeth; Suarez, Jose I 2021. Proceedings of the First Curing Coma Campaign NIH Symposium: Challenging the Future of Research for Coma and Disorders of Consciousness. Neurocritical care, 35 Suppl 1, 4-23Foreman, Brandon; Lee, Hyunjo; Mizrahi, Moshe A; Hartings, Jed A; Ngwenya, Laura B; Privitera, Michael; Tortella, Frank C; Zhang, Nanhua; Kramer, Joel H 2021. Seizures and Cognitive Outcome After Traumatic Brain Injury: A Post Hoc Analysis. Neurocritical care, , Hartings, Jed A; Carroll, Christopher P; Lee, Gregory 2021. Spreading Diffusion-Restriction Events in the Gyrencephalic Brain After Subarachnoid Hemorrhage Revealed by Continuous Magnetic Resonance Imaging. Neurocritical care, , Jewell, Sharon; Hobson, Stephen; Brewer, Grant; Rogers, Michelle; Hartings, Jed A; Foreman, Brandon; Lavrador, José-Pedro; Sole, Michael; Pahl, Clemens; Boutelle, Martyn G; Strong, Anthony J 2021. Development and Evaluation of a Method for Automated Detection of Spreading Depolarizations in the Injured Human Brain. Neurocritical care, 35 Suppl 2, 160-175Barhorst, Kinsey A; Alfawares, Yara; McGuire, Jennifer L; Danzer, Steve C; Hartings, Jed A; Ngwenya, Laura B 2020. Remote and Persistent Alterations in Glutamate Receptor Subunit Composition Induced by Spreading Depolarizations in Rat Brain. Cellular and molecular neurobiology, , Hartings, Jed A; Andaluz, Norberto; Bullock, M Ross; Hinzman, Jason M; Mathern, Bruce; Pahl, Clemens; Puccio, Ava; Shutter, Lori A; Strong, Anthony J; Vagal, Achala; Wilson, J Adam; Dreier, Jens P; Ngwenya, Laura B; Foreman, Brandon; Pahren, Laura; Lingsma, Hester; Okonkwo, David O 2020. Prognostic Value of Spreading Depolarizations in Patients With Severe Traumatic Brain Injury. JAMA neurology, 77 4, 489-499Helbok, Raimund; Hartings, Jed A; Schiefecker, Alois; Balança, Baptiste; Jewel, Sharon; Foreman, Brandon; Ercole, Ari; Balu, Ramani; Ayata, Cenk; Ngwenya, Laura; Rosenthal, Eric; Boutelle, Martyn G; Farkas, Eszter; Dreier, Jens P; Fabricius, Martin; Shuttleworth, C William; Carlson, Andrew 2020. What Should a Clinician Do When Spreading Depolarizations are Observed in a Patient? Neurocritical care, 32 1, 306-310Provencio, J Javier; Hemphill, J Claude; Claassen, Jan; Edlow, Brian L; Helbok, Raimund; Vespa, Paul M; Diringer, Michael N; Polizzotto, Len; Shutter, Lori; Suarez, Jose I; Stevens, Robert D; Hanley, Daniel F; Akbari, Yama; Bleck, Thomas P; Boly, Melanie; Foreman, Brandon; Giacino, Joseph T; Hartings, Jed A; Human, Theresa; Kondziella, Daniel; Ling, Geoffrey S F; Mayer, Stephan A; McNett, Molly; Menon, David K; Meyfroidt, Geert; Monti, Martin M; Park, Soojin; Pouratian, Nader; Puybasset, Louis; Rohaut, Benjamin; Rosenthal, Eric S; Schiff, Nicholas D; Sharshar, Tarek; Wagner, Amy; Whyte, John; Olson, DaiWai M 2020. The Curing Coma Campaign: Framing Initial Scientific Challenges-Proceedings of the First Curing Coma Campaign Scientific Advisory Council Meeting. Neurocritical care, 33 1, 1-12Shuttleworth, C William; Andrew, R David; Akbari, Yama; Ayata, Cenk; Balu, Ramani; Brennan, K C; Boutelle, Martyn; Carlson, Andrew P; Dreier, Jens P; Fabricius, Martin; Farkas, Eszter; Foreman, Brandon; Helbok, Raimund; Henninger, Nils; Jewell, Sharon L; Jones, Stephen C; Kirov, Sergei A; Lindquist, Britta E; Maciel, Carolina B; Okonkwo, David; Reinhart, Katelyn M; Robertson, R Meldrum; Rosenthal, Eric S; Watanabe, Tomas; Hartings, Jed A 2020. Which Spreading Depolarizations Are Deleterious To Brain Tissue? Neurocritical care, 32 1, 317-322Dreier, Jens P; Major, Sebastian; Lemale, Coline L; Kola, Vasilis; Reiffurth, Clemens; Schoknecht, Karl; Hecht, Nils; Hartings, Jed A; Woitzik, Johannes 2019. Correlates of Spreading Depolarization, Spreading Depression, and Negative Ultraslow Potential in Epidural Versus Subdural Electrocorticography. Frontiers in neuroscience, 13 , 373Eriksen, Nina; Pakkenberg, Bente; Rostrup, Egill; Okonkwo, David O; Mathern, Bruce; Shutter, Lori A; Strong, Anthony J; Woitzik, Johannes; Pahl, Clemens; Dreier, Jens P; Martus, Peter; Lauritzen, Martin J; Fabricius, Martin; Hartings, Jed A 2019. Neurostereologic Lesion Volumes and Spreading Depolarizations in Severe Traumatic Brain Injury Patients: A Pilot Study. Neurocritical care, 30 3, 557-568Eriksen, Nina; Rostrup, Egill; Fabricius, Martin; Scheel, Michael; Major, Sebastian; Winkler, Maren K L; Bohner, Georg; Santos, Edgar; Sakowitz, Oliver W; Kola, Vasilis; Reiffurth, Clemens; Hartings, Jed A; Vajkoczy, Peter; Woitzik, Johannes; Martus, Peter; Lauritzen, Martin; Pakkenberg, Bente; Dreier, Jens P 2019. Early focal brain injury after subarachnoid hemorrhage correlates with spreading depolarizations. Neurology, 92 4, e326-e341Hartings, Jed A 2019. How slow can you go? Nature materials, 18 3, 194-196Lee, Hyunjo; Mizrahi, Moshe A; Hartings, Jed A; Sharma, Sameer; Pahren, Laura; Ngwenya, Laura B; Moseley, Brian D; Privitera, Michael; Tortella, Frank C; Foreman, Brandon 2019. Continuous Electroencephalography After Moderate to Severe Traumatic Brain Injury. Critical care medicine, 47 4, 574-582Santos, Edgar; Olivares-Rivera, Arturo; Major, Sebastian; Sánchez-Porras, Renán; Uhlmann, Lorenz; Kunzmann, Kevin; Zerelles, Roland; Kentar, Modar; Kola, Vasilis; Aguilera, Adrian Hernández; Herrera, Mildred Gutierrez; Lemale, Coline L; Woitzik, Johannes; Hartings, Jed A; Sakowitz, Oliver W; Unterberg, Andreas W; Dreier, Jens P 2019. Lasting s-ketamine block of spreading depolarizations in subarachnoid hemorrhage: a retrospective cohort study. Critical care (London, England), 23 1, 427Carlson, Andrew P; Shuttleworth, C William; Major, Sebastian; Lemale, Coline L; Dreier, Jens P; Hartings, Jed A 2018. Terminal spreading depolarizations causing electrocortical silencing prior to clinical brain death: case report. Journal of neurosurgery, 131 6, 1773-1779Dreier, Jens P; Major, Sebastian; Foreman, Brandon; Winkler, Maren K L; Kang, Eun-Jeung; Milakara, Denny; Lemale, Coline L; DiNapoli, Vince; Hinzman, Jason M; Woitzik, Johannes; Andaluz, Norberto; Carlson, Andrew; Hartings, Jed A 2018. Terminal spreading depolarization and electrical silence in death of human cerebral cortex. Annals of neurology, 83 2, 295-310Foreman, Brandon; Ngwenya, Laura B; Stoddard, Erica; Hinzman, Jason M; Andaluz, Norberto; Hartings, Jed A 2018. Safety and Reliability of Bedside, Single Burr Hole Technique for Intracranial Multimodality Monitoring in Severe Traumatic Brain Injury. Neurocritical care, 29 3, 469-480Hartings, Jed A; Ngwenya, Laura B; Carroll, Christopher P; Foreman, Brandon 2018. Letter to the Editor. Ketamine sedation for the suppression of spreading depolarizations. Journal of neurosurgery, , 1-2Hartings, Jed A; Ngwenya, Laura B; Watanabe, Tomas; Foreman, Brandon 2018. Commentary: Detecting Cortical Spreading Depolarization with Full Band Scalp Electroencephalography: An Illusion? Frontiers in systems neuroscience, 12 , 19Lückl, Janos; Lemale, Coline L; Kola, Vasilis; Horst, Viktor; Khojasteh, Uldus; Oliveira-Ferreira, Ana I; Major, Sebastian; Winkler, Maren K L; Kang, Eun-Jeung; Schoknecht, Karl; Martus, Peter; Hartings, Jed A; Woitzik, Johannes; Dreier, Jens P 2018. The negative ultraslow potential, electrophysiological correlate of infarction in the human cortex. Brain : a journal of neurology, 141 6, 1734-1752Schinke, Christian; Horst, Viktor; Schlemm, Ludwig; Wawra, Matthias; Scheel, Michael; Hartings, Jed A; Dreier, Jens P 2018. A case report of delayed cortical infarction adjacent to sulcal clots after traumatic subarachnoid hemorrhage in the absence of proximal vasospasm. BMC neurology, 18 1, 210Cnossen, Maryse C; Huijben, Jilske A; van der Jagt, Mathieu; Volovici, Victor; van Essen, Thomas; Polinder, Suzanne; Nelson, David; Ercole, Ari; Stocchetti, Nino; Citerio, Giuseppe; Peul, Wilco C; Maas, Andrew I R; Menon, David; Steyerberg, Ewout W; Lingsma, Hester F 2017. Variation in monitoring and treatment policies for intracranial hypertension in traumatic brain injury: a survey in 66 neurotrauma centers participating in the CENTER-TBI study. Critical care (London, England), 21 1, 233Hartings JA 2017. Spreading depolarization monitoring in neurocritical care of acute brain injury Current Opinion in Critical Care, 23 2, 94Hartings, Jed A 2017. Spreading depolarization monitoring in neurocritical care of acute brain injury. Current opinion in critical care, 23 2, 94-102Hartings, Jed A; Dreier, Jens P 2017. Real-time detection of lesion development in acute brain injury. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 37 5, 1550-1552Hartings, Jed A; York, Jonathan; Carroll, Christopher P; Hinzman, Jason M; Mahoney, Eric; Krueger, Bryan; Winkler, Maren K L; Major, Sebastian; Horst, Viktor; Jahnke, Paul; Woitzik, Johannes; Kola, Vasilis; Du, Yifeng; Hagen, Matthew; Jiang, Jianxiong; Dreier, Jens P 2017. Subarachnoid blood acutely induces spreading depolarizations and early cortical infarction. Brain : a journal of neurology, 140 10, 2673-2690Maas, Andrew I R; Menon, David K; Adelson, P David; Andelic, Nada; Bell, Michael J; Belli, Antonio; Bragge, Peter; Brazinova, Alexandra; Büki, András; Chesnut, Randall M; Citerio, Giuseppe; Coburn, Mark; Cooper, D Jamie; Crowder, A Tamara; Czeiter, Endre; Czosnyka, Marek; Diaz-Arrastia, Ramon; Dreier, Jens P; Duhaime, Ann-Christine; Ercole, Ari; van Essen, Thomas A; Feigin, Valery L; Gao, Guoyi; Giacino, Joseph; Gonzalez-Lara, Laura E; Gruen, Russell L; Gupta, Deepak; Hartings, Jed A; Hill, Sean; Jiang, Ji-Yao; Ketharanathan, Naomi; Kompanje, Erwin J O; Lanyon, Linda; Laureys, Steven; Lecky, Fiona; Levin, Harvey; Lingsma, Hester F; Maegele, Marc; Majdan, Marek; Manley, Geoffrey; Marsteller, Jill; Mascia, Luciana; McFadyen, Charles; Mondello, Stefania; Newcombe, Virginia; Palotie, Aarno; Parizel, Paul M; Peul, Wilco; Piercy, James; Polinder, Suzanne; Puybasset, Louis; Rasmussen, Todd E; Rossaint, Rolf; Smielewski, Peter; Söderberg, Jeannette; Stanworth, Simon J; Stein, Murray B; von Steinbüchel, Nicole; Stewart, William; Steyerberg, Ewout W; Stocchetti, Nino; Synnot, Anneliese; Te Ao, Braden; Tenovuo, Olli; Theadom, Alice; Tibboel, Dick; Videtta, Walter; Wang, Kevin K W; Williams, W Huw; Wilson, Lindsay; Yaffe, Kristine 2017. Traumatic brain injury: integrated approaches to improve prevention, clinical care, and research. The Lancet. Neurology, 16 12, 987-1048Milakara, Denny; Grozea, Cristian; Dahlem, Markus; Major, Sebastian; Winkler, Maren K L; Lückl, Janos; Scheel, Michael; Kola, Vasilis; Schoknecht, Karl; Lublinsky, Svetlana; Friedman, Alon; Martus, Peter; Hartings, Jed A; Woitzik, Johannes; Dreier, Jens P 2017. Simulation of spreading depolarization trajectories in cerebral cortex: Correlation of velocity and susceptibility in patients with aneurysmal subarachnoid hemorrhage. NeuroImage. Clinical, 16 , 524-538Pinczolits A, Zdunczyk A, Dengler NF, Hecht N, Kowoll CM, Dohmen C, Graf R, Winkler MK, Major S, Hartings JA, Dreier JP, Vajkoczy P, Woitzik J. 2017. Standard-sampling microdialysis and spreading depolarizations in patients with malignant hemispheric stroke Journal of Cerebral Blood Flow and Metabolism , 37 5, 1896Pinczolits, Alexandra; Zdunczyk, Anna; Dengler, Nora F; Hecht, Nils; Kowoll, Christina M; Dohmen, Christian; Graf, Rudolf; Winkler, Maren Kl; Major, Sebastian; Hartings, Jed A; Dreier, Jens P; Vajkoczy, Peter; Woitzik, Johannes 2017. Standard-sampling microdialysis and spreading depolarizations in patients with malignant hemispheric stroke. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 37 5, 1896-19055. Wu Z, Li C, Hartings JA, Narayan R, Ahn C 2016. Polysilicon thin film developed on flexible polyimide for biomedical applications . IEEE Journal of Microelectromechanical Systems , 25 4, 585Bogdanov, Volodymyr B; Middleton, Natalie A; Theriot, Jeremy J; Parker, Patrick D; Abdullah, Osama M; Ju, Y Sungtaek; Hartings, Jed A; Brennan, K C 2016. Susceptibility of Primary Sensory Cortex to Spreading Depolarizations. The Journal of neuroscience : the official journal of the Society for Neuroscience, 36 17, 4733-43Dreier, Jens P; Fabricius, Martin; Ayata, Cenk; Sakowitz, Oliver W; William Shuttleworth, C; Dohmen, Christian; Graf, Rudolf; Vajkoczy, Peter; Helbok, Raimund; Suzuki, Michiyasu; Schiefecker, Alois J; Major, Sebastian; Winkler, Maren Kl; Kang, Eun-Jeung; Milakara, Denny; Oliveira-Ferreira, Ana I; Reiffurth, Clemens; Revankar, Gajanan S; Sugimoto, Kazutaka; Dengler, Nora F; Hecht, Nils; Foreman, Brandon; Feyen, Bart; Kondziella, Daniel; Friberg, Christian K; Piilgaard, Henning; Rosenthal, Eric S; Westover, M Brandon; Maslarova, Anna; Santos, Edgar; Hertle, Daniel; Sánchez-Porras, Renán; Jewell, Sharon L; Balança, Baptiste; Platz, Johannes; Hinzman, Jason M; Lückl, Janos; Schoknecht, Karl; Schöll, Michael; Drenckhahn, Christoph; Feuerstein, Delphine; Eriksen, Nina; Horst, Viktor; Bretz, Julia S; Jahnke, Paul; Scheel, Michael; Bohner, Georg; Rostrup, Egill; Pakkenberg, Bente; Heinemann, Uwe; Claassen, Jan; Carlson, Andrew P; Kowoll, Christina M; Lublinsky, Svetlana; Chassidim, Yoash; Shelef, Ilan; Friedman, Alon; Brinker, Gerrit; Reiner, Michael; Kirov, Sergei A; Andrew, R David; Farkas, Eszter; Güresir, Erdem; Vatter, Hartmut; Chung, Lee S; Brennan, K C; Lieutaud, Thomas; Marinesco, Stephane; Maas, Andrew Ir; Sahuquillo, Juan; Dahlem, Markus A; Richter, Frank; Herreras, Oscar; Boutelle, Martyn G; Okonkwo, David O; Bullock, M Ross; Witte, Otto W; Martus, Peter; van den Maagdenberg, Arn Mjm; Ferrari, Michel D; Dijkhuizen, Rick M; Shutter, Lori A; Andaluz, Norberto; Schulte, André P; MacVicar, Brian; Watanabe, Tomas; Woitzik, Johannes; Lauritzen, Martin; Strong, Anthony J; Hartings, Jed A 2016. Recording, analysis, and interpretation of spreading depolarizations in neurointensive care: Review and recommendations of the COSBID research group. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, , Drenckhahn, Christoph; Windler, Claudia; Major, Sebastian; Kang, Eun-Jeung; Scheel, Michael; Vajkoczy, Peter; Hartings, Jed A; Woitzik, Johannes; Dreier, Jens P 2016. Complications in Aneurysmal Subarachnoid Hemorrhage Patients With and Without Subdural Electrode Strip for Electrocorticography. Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society, 33 3, 250-9Hartings, Jed A; Li, Chunyan; Hinzman, Jason M; Shuttleworth, C William; Ernst, Griffin L; Dreier, Jens P; Wilson, J Adam; Andaluz, Norberto; Foreman, Brandon; Carlson, Andrew P 2016. Direct current electrocorticography for clinical neuromonitoring of spreading depolarizations. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, , Hartings, Jed A; Shuttleworth, C William; Kirov, Sergei A; Ayata, Cenk; Hinzman, Jason M; Foreman, Brandon; Andrew, R David; Boutelle, Martyn G; Brennan, K C; Carlson, Andrew P; Dahlem, Markus A; Drenckhahn, Christoph; Dohmen, Christian; Fabricius, Martin; Farkas, Eszter; Feuerstein, Delphine; Graf, Rudolf; Helbok, Raimund; Lauritzen, Martin; Major, Sebastian; Oliveira-Ferreira, Ana I; Richter, Frank; Rosenthal, Eric S; Sakowitz, Oliver W; Sánchez-Porras, Renán; Santos, Edgar; Schöll, Michael; Strong, Anthony J; Urbach, Anja; Westover, M Brandon; Winkler, Maren Kl; Witte, Otto W; Woitzik, Johannes; Dreier, Jens P 2016. The continuum of spreading depolarizations in acute cortical lesion development: Examining Leão's legacy. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, , Li, Chunyan; Narayan, Raj K; Wang, Ping; Hartings, Jed A 2016. Regional temperature and quantitative cerebral blood flow responses to cortical spreading depolarization in the rat. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, , Li, Chunyan; Narayan, Raj K; Wu, Pei-Ming; Rajan, Neena; Wu, Zhizhen; Mehan, Neal; Golanov, Eugene V; Ahn, Chong H; Hartings, Jed A 2016. Evaluation of microelectrode materials for direct-current electrocorticography. Journal of neural engineering, 13 1, 016008Li, Chunyan; Wu, Zhizhen; Limnuson, Kanokwan; Cheyuo, Cletus; Wang, Ping; Ahn, Chong H; Narayan, Raj K; Hartings, Jed A 2016. Development and application of a microfabricated multimodal neural catheter for neuroscience. Biomedical microdevices, 18 1, 8Toth, Peter; Szarka, Nikolett; Farkas, Eszter; Ezer, Erzsebet; Czeiter, Endre; Amrein, Krisztina; Ungvari, Zoltan; Hartings, Jed A; Buki, Andras; Koller, Akos 2016. Traumatic brain injury-induced autoregulatory dysfunction and spreading depression-related neurovascular uncoupling: Pathomechanisms, perspectives, and therapeutic implications. American journal of physiology. Heart and circulatory physiology, 311 5, H1118-H1131Winkler, Maren Kl; Dengler, Nora; Hecht, Nils; Hartings, Jed A; Kang, Eun J; Major, Sebastian; Martus, Peter; Vajkoczy, Peter; Woitzik, Johannes; Dreier, Jens P 2016. Oxygen availability and spreading depolarizations provide complementary prognostic information in neuromonitoring of aneurysmal subarachnoid hemorrhage patients. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, , Wu Z, Li C, Hartings JA, Narayan RK, Ahn C 2016. Polysilicon based flexible temperature sensor for high resolution brain temperature monitoring . Conf Proc IEEE Eng Med Biol Soc , , 500Hinzman, Jason M; DiNapoli, Vince A; Mahoney, Eric J; Gerhardt, Greg A; Hartings, Jed A 2015. Spreading depolarizations mediate excitotoxicity in the development of acute cortical lesions. Experimental neurology, 267 , 243-53Hinzman, Jason M; Gibson, Justin L; Tackla, Ryan D; Costello, Mark S; Burmeister, Jason J; Quintero, Jorge E; Gerhardt, Greg A; Hartings, Jed A 2015. Real-time monitoring of extracellular adenosine using enzyme-linked microelectrode arrays. Biosensors & bioelectronics, 74 , 512-517Hinzman, Jason; Wilson, J Adam; Mazzeo, Anna Teresa; Bullock, Ross; Hartings, Jed A 2015. Excitotoxicity and Metabolic Crisis Are Associated with Spreading Depolarizations in Severe Traumatic Brain Injury Patients. Journal of neurotrauma, , Li, Chunyan; Limnuson, Kanokwan; Wu, Zhizhen; Amin, Aseer; Narayan, Anjali; Golanov, Eugene V; Ahn, Chong H; Hartings, Jed A; Narayan, Raj K 2015. Single probe for real-time simultaneous monitoring of neurochemistry and direct-current electrocorticography. Biosensors & bioelectronics, 77 , 62-68Li, Chunyan; Wu, Pei-Ming; Wu, Zhizhen; Limnuson, Kanokwan; Mehan, Neal; Mozayan, Cameron; Golanov, Eugene V; Ahn, Chong H; Hartings, Jed A; Narayan, Raj K 2015. Highly accurate thermal flow microsensor for continuous and quantitative measurement of cerebral blood flow. Biomedical microdevices, 17 5, 9992Maas, Andrew I R; Menon, David K; Steyerberg, Ewout W; Citerio, Giuseppe; Lecky, Fiona; Manley, Geoffrey T; Hill, Sean; Legrand, Valerie; Sorgner, Annina 2015. Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI): a prospective longitudinal observational study. Neurosurgery, 76 1, 67-80Tackla, Ryan; Hinzman, Jason M; Foreman, Brandon; Magner, Mark; Andaluz, Norberto; Hartings, Jed A 2015. Assessment of Cerebrovascular Autoregulation Using Regional Cerebral Blood Flow in Surgically Managed Brain Trauma Patients. Neurocritical care, , Jeffcote, Toby; Hinzman, Jason M; Jewell, Sharon L; Learney, Robert M; Pahl, Clemens; Tolias, Christos; Walsh, Daniel C; Hocker, Sara; Zakrzewska, Agnieszka; Fabricius, Martin E; Strong, Anthony J; Hartings, Jed A; Boutelle, Martyn G 2014. Detection of spreading depolarization with intraparenchymal electrodes in the injured human brain. Neurocritical care, 20 1, 21-31Dreier, Jens P; Drenckhahn, Christoph; Woitzik, Johannes; Major, Sebastian; Offenhauser, Nikolas; Weber-Carstens, Steffen; Wolf, Stefan; Strong, Anthony J; Vajkoczy, Peter; Hartings, Jed A 2013. Spreading Ischemia After Aneurysmal Subarachnoid Hemorrhage. Acta neurochirurgica. Supplement, 115 , 125-129Hartings, Jed A; Vidgeon, Steven; Strong, Anthony J; Zacko, Chris; Vagal, Achala; Andaluz, Norberto; Ridder, Thomas; Stanger, Richard; Fabricius, Martin; Mathern, Bruce; Pahl, Clemens; Tolias, Christos M; Bullock, M Ross 2013. Surgical management of traumatic brain injury: a comparative-effectiveness study of 2 centers. Journal of neurosurgery, , Hartings, Jed A; Wilson, J Adam; Look, Andrew C; Vagal, Achala; Shutter, Lori A; Dreier, Jens P; Ringer, Andrew; Zuccarello, Mario 2013. Full-band electrocorticography of spreading depolarizations in patients with aneurysmal subarachnoid hemorrhage. Acta neurochirurgica. Supplement, 115 , 131-41Serrone, Joseph C; Wash, Erin M; Hartings, Jed A; Andaluz, Norberto; Zuccarello, Mario 2013. Venous Thromboembolism in Subarachnoid Hemorrhage. World neurosurgery, , Wilson, J Adam; Shutter, Lori A; Hartings, Jed A 2013. COSBID-M3: A Platform for Multimodal Monitoring, Data Collection, and Research in Neurocritical Care. Acta neurochirurgica. Supplement, 115 , 67-74Dreier, Jens P; Major, Sebastian; Pannek, Heinz-Wolfgang; Woitzik, Johannes; Scheel, Michael; Wiesenthal, Dirk; Martus, Peter; Winkler, Maren K L; Hartings, Jed A; Fabricius, Martin; Speckmann, Erwin-Josef; Gorji, Ali 2012. Spreading convulsions, spreading depolarization and epileptogenesis in human cerebral cortex. Brain : a journal of neurology, 135 Pt 1, 259-75Drenckhahn, Christoph; Winkler, Maren K L; Major, Sebastian; Scheel, Michael; Kang, Eun-Jeung; Pinczolits, Alexandra; Grozea, Cristian; Hartings, Jed A; Woitzik, Johannes; Dreier, Jens P 2012. Correlates of spreading depolarization in human scalp electroencephalography. Brain : a journal of neurology, 135 Pt 3, 853-68Hertle, Daniel N; Dreier, Jens P; Woitzik, Johannes; Hartings, Jed A; Bullock, Ross; Okonkwo, David O; Shutter, Lori A; Vidgeon, Steven; Strong, Anthony J; Kowoll, Christina; Dohmen, Christian; Diedler, Jennifer; Veltkamp, Roland; Bruckner, Thomas; Unterberg, Andreas W; Sakowitz, Oliver W 2012. Effect of analgesics and sedatives on the occurrence of spreading depolarizations accompanying acute brain injury. Brain : a journal of neurology, 135 Pt 8, 2390-2398Li, Chunyan; Wu, Pei-Ming; Hartings, Jed A; Wu, Zhizhen; Cheyuo, Cletus; Wang, Ping; Ledoux, David; Shutter, Lori A; Ramaswamy, Bharat Ram; Ahn, Chong H; Narayan, Raj K 2012. Micromachined lab-on-a-tube sensors for simultaneous brain temperature and cerebral blood flow measurements. Biomedical microdevices, , Li, Chunyan; Wu, Pei-Ming; Wu, Zhizhen; Ahn, Chong H; LeDoux, David; Shutter, Lori A; Hartings, Jed A; Narayan, Raj K 2012. Brain temperature measurement: A study of in vitro accuracy and stability of smart catheter temperature sensors. Biomedical microdevices, 14 1, 109-18Li, Chunyan; Wu, Zhizhen; Hartings, Jed A; Rajan, Neena; Chahine, Nadeen; Cheyuo, Cletus; Wang, Ping; Wu, Pei-Ming; Golanov, Eugene V; Ahn, Chong H; Narayan, Raj K 2012. Brain-friendly amperometric enzyme biosensor based on encapsulated oxygen generating biomaterial. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference, 2012 , 6003-6Fioravanti, Beatriz; Kasasbeh, Aimen; Edelmayer, Rebecca; Skinner, David P; Hartings, Jed A; Burklund, Ryan D; De Felice, Milena; French, Edward D; Dussor, Greg O; Dodick, David W; Porreca, Frank; Vanderah, Todd W 2011. Evaluation of cutaneous allodynia following induction of cortical spreading depression in freely moving rats. Cephalalgia : an international journal of headache, 31 10, 1090-100Hartings, Jed A; Bullock, M Ross; Okonkwo, David O; Murray, Lilian S; Murray, Gordon D; Fabricius, Martin; Maas, Andrew Ir; Woitzik, Johannes; Sakowitz, Oliver; Mathern, Bruce; Roozenbeek, Bob; Lingsma, Hester; Dreier, Jens P; Puccio, Ava M; Shutter, Lori A; Pahl, Clemens; Strong, Anthony J 2011. Spreading depolarisations and outcome after traumatic brain injury: a prospective observational study. Lancet neurology, 10 12, 1058-64Hartings, Jed A; Watanabe, Tomas; Bullock, M Ross; Okonkwo, David O; Fabricius, Martin; Woitzik, Johannes; Dreier, Jens P; Puccio, Ava; Shutter, Lori A; Pahl, Clemens; Strong, Anthony J 2011. Spreading depolarizations have prolonged direct current shifts and are associated with poor outcome in brain trauma. Brain : a journal of neurology, 134 Pt 5, 1529-40Lauritzen, Martin; Dreier, Jens Peter; Fabricius, Martin; Hartings, Jed A; Graf, Rudolf; Strong, Anthony John 2011. Clinical relevance of cortical spreading depression in neurological disorders: migraine, malignant stroke, subarachnoid and intracranial hemorrhage, and traumatic brain injury. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 31 1, 17-35Lu, Xi-Chun May; Hartings, Jed A; Si, Yuanzheng; Balbir, Alexander; Cao, Ying; Tortella, Frank C 2011. Electrocortical pathology in a rat model of penetrating ballistic-like brain injury. Journal of neurotrauma, 28 1, 71-83Eriksen, N; Rostrup, E; Andersen, K; Lauritzen, M J; Fabricius, M; Larsen, V A; Dreier, J P; Strong, A J; Hartings, J A; Pakkenberg, B 2010. Application of stereological estimates in patients with severe head injuries using CT and MR scanning images. The British journal of radiology, 83 988, 307-17Oliveira-Ferreira, Ana I; Milakara, Denny; Alam, Mesbah; Jorks, Devi; Major, Sebastian; Hartings, Jed A; Lückl, Janos; Martus, Peter; Graf, Rudolf; Dohmen, Christian; Bohner, Georg; Woitzik, Johannes; Dreier, Jens P 2010. Experimental and preliminary clinical evidence of an ischemic zone with prolonged negative DC shifts surrounded by a normally perfused tissue belt with persistent electrocorticographic depression. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 30 8, 1504-19Dreier, Jens P; Major, Sebastian; Manning, Andrew; Woitzik, Johannes; Drenckhahn, Chistoph; Steinbrink, Jens; Tolias, Christos; Oliveira-Ferreira, Ana I; Fabricius, Martin; Hartings, Jed A; Vajkoczy, Peter; Lauritzen, Martin; Dirnagl, Ulrich; Bohner, Georg; Strong, Anthony J 2009. Cortical spreading ischaemia is a novel process involved in ischaemic damage in patients with aneurysmal subarachnoid haemorrhage. Brain : a journal of neurology, 132 Pt 7, 1866-81Hartings, Jed A; Strong, Anthony J; Fabricius, Martin; Manning, Andrew; Bhatia, Robin; Dreier, Jens P; Mazzeo, Anna Teresa; Tortella, Frank C; Bullock, M Ross 2009. Spreading depolarizations and late secondary insults after traumatic brain injury. Journal of neurotrauma, 26 11, 1857-66Hartings, Jed A; Watanabe, Tomas; Dreier, Jens P; Major, Sebastian; Vendelbo, Leif; Fabricius, Martin 2009. Recovery of slow potentials in AC-coupled electrocorticography: application to spreading depolarizations in rat and human cerebral cortex. Journal of neurophysiology, 102 4, 2563-75Lu, Xi-Chun M; Si, Yuanzheng; Williams, Anthony J; Hartings, Jed A; Gryder, Divina; Tortella, Frank C 2009. NNZ-2566, a glypromate analog, attenuates brain ischemia-induced non-convulsive seizures in rats. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 29 12, 1924-32Fabricius, Martin; Fuhr, Susanne; Willumsen, Lisette; Dreier, Jens P; Bhatia, Robin; Boutelle, Martyn G; Hartings, Jed A; Bullock, Ross; Strong, Anthony J; Lauritzen, Martin 2008. Association of seizures with cortical spreading depression and peri-infarct depolarisations in the acutely injured human brain. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 119 9, 1973-84Hartings, Jed A; Gugliotta, Marinella; Gilman, Charlotte; Strong, Anthony J; Tortella, Frank C; Bullock, M Ross 2008. Repetitive cortical spreading depolarizations in a case of severe brain trauma. Neurological research, 30 8, 876-82Wei, Guo; Hartings, Jed A; Yang, Xiaofang; Tortella, Frank C; Lu, Xi-Chun M 2008. Extraluminal cooling of bilateral common carotid arteries as a method to achieve selective brain cooling for neuroprotection. Journal of neurotrauma, 25 5, 549-59Williams, Anthony J; Tortella, Frank C; Gryder, Divina; Hartings, Jed A 2008. Topiramate reduces non-convulsive seizures after focal brain ischemia in the rat. Neuroscience letters, 430 1, 7-12Strong, Anthony J; Hartings, Jed A; Dreier, Jens P 2007. Cortical spreading depression: an adverse but treatable factor in intensive care? Current opinion in critical care, 13 2, 126-33Dreier, Jens P; Woitzik, Johannes; Fabricius, Martin; Bhatia, Robin; Major, Sebastian; Drenckhahn, Chistoph; Lehmann, Thomas-Nicolas; Sarrafzadeh, Asita; Willumsen, Lisette; Hartings, Jed A; Sakowitz, Oliver W; Seemann, Jörg H; Thieme, Anja; Lauritzen, Martin; Strong, Anthony J 2006. Delayed ischaemic neurological deficits after subarachnoid haemorrhage are associated with clusters of spreading depolarizations. Brain : a journal of neurology, 129 Pt 12, 3224-37Hartings, Jed A; Tortella, Frank C; Rolli, Michael L 2006. AC electrocorticographic correlates of peri-infarct depolarizations during transient focal ischemia and reperfusion. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 26 5, 696-707Williams, Anthony J; Bautista, Charisma C; Chen, Ren-Wu; Dave, Jitendra R; Lu, Xi-Chun M; Tortella, Frank C; Hartings, Jed A 2006. Evaluation of gabapentin and ethosuximide for treatment of acute nonconvulsive seizures following ischemic brain injury in rats. The Journal of pharmacology and experimental therapeutics, 318 3, 947-55Williams, Anthony J; Hartings, Jed A; Lu, Xi-Chun M; Rolli, Michael L; Tortella, Frank C 2006. Penetrating ballistic-like brain injury in the rat: differential time courses of hemorrhage, cell death, inflammation, and remote degeneration. Journal of neurotrauma, 23 12, 1828-46Lu, X-C May; Williams, Anthony J; Wagstaff, John D; Tortella, Frank C; Hartings, Jed A 2005. Effects of delayed intrathecal infusion of an NMDA receptor antagonist on ischemic injury and peri-infarct depolarizations. Brain research, 1056 2, 200-8Williams, Anthony J; Hartings, Jed A; Lu, X-C May; Rolli, Michael L; Dave, Jitendra R; Tortella, Frank C 2005. Characterization of a new rat model of penetrating ballistic brain injury. Journal of neurotrauma, 22 2, 313-31Yao, C; Williams, A J; Hartings, J A; Lu, X-C M; Tortella, F C; Dave, J R 2005. Down-regulation of the sodium channel Na(v)1.1 alpha-subunit following focal ischemic brain injury in rats: in situ hybridization and immunohistochemical analysis. Life sciences, 77 10, 1116-29Khatri, V; Hartings, J A; Simons, D J 2004. Adaptation in thalamic barreloid and cortical barrel neurons to periodic whisker deflections varying in frequency and velocity. Journal of neurophysiology, 92 6, 3244-54Lu, X-C May; Williams, Anthony J; Yao, Changping; Berti, Rossana; Hartings, Jed A; Whipple, Rebecca; Vahey, Maryanne T; Polavarapu, Ratna G; Woller, Kimberly L; Tortella, Frank C; Dave, Jitendra R 2004. Microarray analysis of acute and delayed gene expression profile in rats after focal ischemic brain injury and reperfusion. Journal of neuroscience research, 77 6, 843-57Williams, A J; Tortella, F C; Lu, X M; Moreton, J E; Hartings, J A 2004. Antiepileptic drug treatment of nonconvulsive seizures induced by experimental focal brain ischemia. The Journal of pharmacology and experimental therapeutics, 311 1, 220-7Hartings, Jed A; Rolli, Michael L; Lu, X-C May; Tortella, Frank C 2003. Delayed secondary phase of peri-infarct depolarizations after focal cerebral ischemia: relation to infarct growth and neuroprotection. 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