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Department of

Environmental Health

Photo of Liang Niu

Liang Niu

Education/Credentials
  • Ph.D., Biostatistics: Ohio State University
  • Ph.D., Mathematics: Ohio State University
  • M.S.: Peking University
  • B.S.: Hubei University

Research/Clinical Interests

Bioinformatics and Biostatistics. Omics data analysis. RNA-Seq, ChIA-PET and methylation array data management, processing, and statistical analysis. PacBio data analysis. Metablomics data analysis. Mining of public domain omics datasets (such as TCGA datasets).

Contact Information
  • Kettering Laboratory Room 143
  • 160 Panzeca Way
  • Cincinnati, Ohio 45267
  • Office 513-558-7221

Peer Reviewed Publications

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Hongqi Liu, Xizhi Feng, Kelli N. Ennis, Catherine A. Behrmann, Pranjal Sarma, Tony T. Jiang, Satoshi Kofuji, Liang Niu, Yiwen Stratton, Hala Elnakat Thomas, Sang-Oh Yoon, Atsuo T. Sasaki, David R. Plas 2017. Pharmacologic Targeting of S6K1 in PTEN-Deficient Neoplasia Cell reports, 18 9, 2088

Manju Sharma, Xiang Zhang, Shuangmin Zhang, Liang Niu, Shuk-mei Ho, Aimin Chen, Shouxiong Huang 2017. Inhibition of endocytic lipid antigen presentation by common lipophilic environmental pollutants Scientific Reports, 7 , 2085

Zongli Xu, Sabine A. S. Langie, Patrick De Boever, Jack A. Taylor and Liang Niu 2017. RELIC: a novel dye-bias correction method for Illumina Methylation BeadChip BMC Genomics, 18 4,

Liang Chen, Zhimin Peng, Qinghang Meng, Maureen Mongan, Jingcai Wang, Maureen Sartor, Jing Chen, Liang Niu, Mario Medvedovic, Winston Kao, Ying Xia 2016. Loss of IκB kinase β promotes myofibroblast transformation and senescence through activation of the ROS-TGFβ autocrine loop Protein & Cell, 7 5, 338–350

Liang Niu, Zongli Xu and Jack A. Taylor 2016. RCP: a novel probe design bias correction method for Illumina Methylation BeadChip Bioinformatics, 32 17, 2659-2663

Zongli Xu, Jack A. Taylor, Yuet-Kin Leung, Shuk-Mei Ho and Liang Niu 2016. oxBS-MLE: An efficient method to estimate 5-methylcytosine and 5-hydroxymethylcytosine in paired bisulfite and oxidative bisulfite treated DNA Bioinformatics, 32 23, 3667-3669

Zongli Xu, Liang Niu, Leping Li and Jack A. Taylor 2016. ENmix: a novel background correction method for Illumina HumanMethylation450 BeadChip Nucleic Acids Research, 44 3, e20

Jing Dong, Jingyun Yang, Greg Tranah, Nora Franceschini, Neeta Parimi, Gorka Alkorta-Aranburu, Zongli Xu, Alvaro Alonso, Steven R. Cummings, Myriam Fornage, Xuemei Huang, Stephen Kritchevsky, Yongmei Liu, Stephanie London, Liang Niu, Robert S. Wilson, Philip L. De Jager, Lei Yu, Andrew B. Singleton, Tamara Harris, Thomas H. Mosley Jr, Jayant M. Pinto, David A. Bennett and Honglei Chen 2015. Genome-wide Meta-analysis on the Sense of Smell Among US Older Adults Medicine, 94 47, e1892

Liang Niu and Shili Lin 2015. A Bayesian mixture model for chromatin interaction data Statistical Applications in Genetics and Molecular Biology, 14 1, 53-64

Liang Niu, Guoliang Li and Shili Lin 2014. Statistical models for detecting differential chromatin interactions mediated by a protein PLoS ONE, 9 5, e97560

Liang Niu, Weichun Huang, David M. Umbach and Leping Li 2014. IUTA: a tool for effectively detecting differential isoform usage from RNA-Seq data BMC Genomics, 15 862,

Yuanyuan Li, Weichun Huang, Liang Niu, David M. Umbach, Shay Covo and Leping Li 2013. Characterization of constitutive CTCF/cohesin loci: a possible role in establishing topological domains in mammalian genomes BMC Genomics, 14 553,

Cai Heng Li, Liang Niu, Akos Seress and Ronald Solomon 2010. The vertex primitive and vertex bi-primitive s-arc regular graphs Journal of Combinatorial Theory, Series B, 100 4, 359–366