Alexey Porollo, PhD, focuses on structural and functional annotation of proteins, assessment of the functional and medical effects of missense mutations and modeling of signal transduction pathways. He is also interested in studying metal-binding proteins, antimicrobial resistance, discovery of novel drug targets, comparative genomic analysis and a microbiome assessment. His lab aims to develop prediction and annotation approaches for the assessment of the functional impact of mutations in proteins, finding the processes of copper tolerance in human fungal pathogens, studying host-pathogen interactions and identifying novel drug treatments.

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