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mark.baccei@uc.edu
Website
artem.barski@cchmc.org
basuia@ucmail.uc.edu
bessetde@UCMAIL.UC.EDU
Currently directs a translational research laboratory which focuses on human and mechanistic studies to understand the interactions between various viral pathogens. Using a variety of cell culture systems, molecular virology techniques, and patient-derived samples, I investigate the pathogenic and evolutionary mechanisms by which viruses interact with the host and cause disease. At present, laboratory studies involve hepatitis B virus (HBV), hepatitis C virus (HCV), hepatitis E virus (HEV), pegiviruses (HPgV; GBV-C), and HIV and include international collaborations in South Africa, Botswana, India, Nigeria, and Ghana.
HIV/AIDS pathogenesis; ontogeny of the immune system; immune dysfunction in aging; human immunology.
Zackary.Cleveland@cchmc.org
CONFORL@UCMAIL.UC.EDU
Steven.Crone@cchmc.org
cunnijn@ucmail.uc.edu
Metatranscriptomics and preclinical drug development for treatment of the AIDS-related opportunistic pathogen Pneumocystis carinii.
cushiomt@ucmail.uc.eduWebsite
steve.danzer@cchmc.org
steve.davidson@uc.edu
melissa.delbello@uc.eduWebsite
Using a combination of human studies and developmentally appropriate preclinical models in non-human primates and mice, our lab investigates the cellular components and molecular targets by which intestinal commensal bacteria direct development of innate defenses of the lungs in newborns.
Hitesh.Deshmukh@cchmc.orgWebsite
Judith.Dexheimer@cchmc.org
esfandla@ucmail.uc.eduWebsite 1
Website 2
The overall goals of the Guan laboratory is to understand the fundamental principles of cell signaling in the regulation of basic cellular functions in normal cell and developmental processes and to determine how the disruption of normal signaling pathways lead to diseases such as cancer.
Dr. Hagan’s research is focused on using computational and systems biology approaches to understand immune development, aging, and response to vaccination and infection.
Christy.Holland@uc.eduWebsite 1
Michael.Jankowski@cchmc.org
anil.jegga@cchmc.org
Raphael.Kopan@cchmc.org
The Kottyan lab works to identify the molecular mechanisms mediating the genetic etiology of Systemic lupus erythematous and Eosinophilic Esophagitis.
leah.kottyan@cchmc.org
rhett.kovall@uc.edu
punam.malik@cchmc.org
marti7j3@ucmail.uc.edu
Website 1
doug.mast@uc.edu
Dr. Mersha’s research interests lie in combining quantitative, ancestry and statistical genomics to unravel genetic and non-genetic contributions to asthma and asthma-related allergic disorders in human populations.
tesfaye.mersha@cchmc.org
Molecular regulation of spermatogonial stem cell differentiation into sperm, using single cell sequencing technologies, molecular biology, functional genomics, bioinformatics, biochemistry, and mouse genetics.
Maria.Nicholson@cchmc.org
My lab investigates biological mechanisms behind the development of Acute Myeloid Leukemia (AML) and how co-mutations synergize to drive disease using single cell multi-omics and preclinical mouse models of AML.
Linde.Miles@cchmc.org
Systems biology to immunoengineer, building mathematical models of the immune system from high-dimensional genomics measurements, to re-engineer immune responses in the context of autoimmune and other diseases.
emily.miraldi@cchmc.org
The primary focus of my research is to examine the effects of coagulation proteins, proteases, and receptors in the pathogenesis cardiovascular disease (CVD), specifically atherosclerosis and abdominal aortic aneurysms (AAAs).
Ertugrul.Ozbudak@cchmc.org
parkye@ucmail.uc.edu
Dr. Pestian's lab focuses on developing advanced technology for the care of neuropsychiatric illness. The lab also focuses on earlier identification of individuals at risk of suicide, depression, and bipolar and anxiety disorders using verbal and non-verbal language.
marc.rothenberg@cchmc.org
patrick.ryan@cchmc.org
SADAYASL@ucmail.uc.edu
sahr@ucmail.uc.edu
Pediatric infectious disease; HIV assembly, HIV biology/pathogenesis, HIV vaccines; vaccines and therapeutics for children (clinical trials).
daniel.starczynowski@cchmc.org
Dr. Timchenko is working with molecular mechanisms of Liver Cancer and Non-Alcoholic Fatty Liver Disease. His work focuses on the epigenetic changes that cause these liver diseases.
nikolai.timchenko@cchmc.org
trantemc@ucmail.uc.edu
Research on rare lung diseases including pulmonary alveolar proteinosis, cystic fibrosis, alpha-1 antitrypsin deficiency and lymphangioleiomyomatosis. Mechanisms of alveolar macrophage function. Experimental approaches include molecular techniques using gene knockout, transgenic and conditional gene expression mouse models and non-human primates, in vitro and in vivo viral gene transfer, and bone marrow transplantation.
bruce.trapnell@cchmc.org
The Weirauch lab uses computational and experimental tools to understand the mechanisms of gene transcriptional regulation and how these mechanisms go awry in disease states.
matthew.weirauch@cchmc.org
jason.woods@cchmc.org
yuj9@ucmail.uc.eduWebsite 1
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