Education/CredentialsFellowship: Yale University (Diagnostic Radiology)Doctoral Degree: Yale University (Engineering and Applied Science)Master's Degree: Yale University (Engineering and Applied Science)Master's Degree: Yale University (Engineering and Applied Science)Bachelor's Degree: Wellesley College (Physics and Music (Cum Laude)): University of Freiburg (Studied Beethoven and Schubert) Contact Information Cardiovascular Rsrch Cntr 3935 Office 513-558-5675 Email hollanck@ucmail.uc.edu Research Interests Bioeffects of Diagnostic and Therapeutic Ultrasound Acoustic Cavitation New Diagnostic imaging Techniques for the Early Detection of Vascular Disease and Ischemic Injury to Brain Peer Reviewed Publications Escudero, Daniel Suarez; Lafond, Maxime; Salido, Nuria G; Haworth, Kevin J; Hannah, Alexander S; Macke, Gregory P; Genstler, Curtis; Holland, Christy K 2023. Corrigendum to 'Cavitation emissions nucleated by Definity infused through an EkoSonic catheter in a flow phantom' [Ultrasound in Med & Biol. 47 (2021) 693-709]. Ultrasound in medicine & biology, 49 1, 410-414Kennedy, Sonya R; Lafond, Maxime; Haworth, Kevin J; Escudero, Daniel Suarez; Ionascu, Dan; Frierson, Brion; Huang, Shaoling; Klegerman, Melvin E; Peng, Tao; McPherson, David D; Genstler, Curtis; Holland, Christy K 2023. Initiating and imaging cavitation from infused echo contrast agents through the EkoSonic catheter. Scientific reports, 13 1, 6191Kleven, Robert T; Huang, Shenwen; Ford, Samantha M; Sakthivel, Karthikeyan; Thomas, Seth R; Zuccarello, Mario; Herr, Andrew B; Holland, Christy K 2023. Effect of Recombinant Tissue Plasminogen Activator and 120-kHz Ultrasound on Porcine Intracranial Thrombus Density. Ultrasound in medicine & biology, 49 2, 539-548Suarez Escudero, Daniel; Haworth, Kevin J; Genstler, Curtis; Holland, Christy K 2023. Quantifying the Effect of Acoustic Parameters on Temporal and Spatial Cavitation Activity: Gauging Cavitation Dose. Ultrasound in medicine & biology, 49 11, 2388-2397Hendley, Samuel A; Bhargava, Aarushi; Holland, Christy K; Wool, Geoffrey D; Ahmed, Osman; Paul, Jonathan D; Bader, Kenneth B 2022. (More than) doubling down: Effective fibrinolysis at a reduced rt-PA dose for catheter-directed thrombolysis combined with histotripsy. PloS one, 17 1, e0261567Klegerman, Melvin E; Moody, Melanie R; Huang, Shao-Ling; Peng, Tao; Laing, Susan T; Govindarajan, Vijay; Danila, Delia; Tahanan, Amirali; Rahbar, Mohammad H; Vela, Deborah; Genstler, Curtis; Haworth, Kevin J; Holland, Christy K; McPherson, David D; Kee, Patrick H 2022. Demonstration of ultrasound-mediated therapeutic delivery of fibrin-targeted pioglitazone-loaded echogenic liposomes into the arterial bed for attenuation of peri-stent restenosis. Journal of drug targeting, , 1-10Zemzemi, Chadi; Phillips, Matthew; Vela, Deborah C; Hilvert, Nicole A; Racadio, John M; Bader, Kenneth B; Haworth, Kevin J; Holland, Christy K 2022. Effect of Thrombin and Incubation Time on Porcine Whole Blood Clot Elasticity and Recombinant Tissue Plasminogen Activator Susceptibility. Ultrasound in medicine & biology, 48 8, 1567-1578Karunakaran, Chandra Priya; Burgess, Mark T; Rao, Marepalli B; Holland, Christy K; Mast, T Douglas 2021. Effect of Overpressure on Acoustic Emissions and Treated Tissue Histology in ex Vivo Bulk Ultrasound Ablation. Ultrasound in medicine & biology, 47 8, 2360-2376Kleven, Robert T; Karani, Kunal B; Hilvert, Nicole; Ford, Samantha M; Mercado-Shekhar, Karla P; Racadio, John M; Rao, Marepalli B; Abruzzo, Todd A; Holland, Christy K 2021. Accelerated sonothrombolysis with Definity in a xenographic porcine cerebral thromboembolism model. Scientific reports, 11 1, 3987Lafond, Maxime; Salido, Nuria G; Haworth, Kevin J; Hannah, Alexander S; Macke, Gregory P; Genstler, Curtis; Holland, Christy K 2021. Cavitation Emissions Nucleated by Definity Infused through an EkoSonic Catheter in a Flow Phantom. Ultrasound in medicine & biology, 47 3, 693-709Bollen, Viktor; Hendley, Samuel A; Paul, Jonathan D; Maxwell, Adam D; Haworth, Kevin J; Holland, Christy K; Bader, Kenneth B 2020. In Vitro Thrombolytic Efficacy of Single- and Five-Cycle Histotripsy Pulses and rt-PA. Ultrasound in medicine & biology, 46 2, 336-349Kee, Patrick H; Moody, Melanie R; Huang, Shao-Ling; Kim, Hyunggun; Yin, Xing; Peng, Tao; Laing, Susan T; Klegerman, Melvin E; Rahbar, Mohammad H; Vela, Deborah; Genstler, Curtis; Haworth, Kevin J; Holland, Christy K; McPherson, David D 2020. Stabilizing Peri-Stent Restenosis Using a Novel Therapeutic Carrier. JACC. Basic to translational science, 5 1, 1-11Kooiman, Klazina; Roovers, Silke; Langeveld, Simone A G; Kleven, Robert T; Dewitte, Heleen; O'Reilly, Meaghan A; Escoffre, Jean-Michel; Bouakaz, Ayache; Verweij, Martin D; Hynynen, Kullervo; Lentacker, Ine; Stride, Eleanor; Holland, Christy K 2020. Ultrasound-Responsive Cavitation Nuclei for Therapy and Drug Delivery. Ultrasound in medicine & biology, 46 6, 1296-1325Lattwein, Kirby R; Shekhar, Himanshu; Kouijzer, Joop J P; van Wamel, Willem J B; Holland, Christy K; Kooiman, Klazina 2020. Sonobactericide: An Emerging Treatment Strategy for Bacterial Infections. Ultrasound in medicine & biology, 46 2, 193-215Bader, Kenneth B; Gruber, Matthew J; Holland, Christy K 2019. Corrigendum to: "Shaken and Stirred: Mechanisms of Ultrasound-Enhanced Thrombolysis" in Ultrasound Med Biol 2015; 41(1): 187-196. Ultrasound in medicine & biology, 45 8, 2266Kleven, Robert T; Karani, Kunal B; Salido, Nuria G; Shekhar, Himanshu; Haworth, Kevin J; Mast, T Douglas; Tadesse, Dawit G; Holland, Christy K 2019. The effect of 220?kHz insonation scheme on rt-PA thrombolytic efficacy in vitro. Physics in medicine and biology, 64 16, 165015Lafond, Maxime; Shekhar, Himanshu; Panmanee, Warunya; Collins, Sydney D; Palaniappan, Arunkumar; McDaniel, Cameron T; Hassett, Daniel J; Holland, Christy K 2019. Bactericidal Activity of Lipid-Shelled Nitric Oxide-Loaded Microbubbles. Frontiers in pharmacology, 10 , 1540Mercado-Shekhar, Karla P; Kleven, Robert; Rivera, Hermes Aponte; Lewis, Ryden; Karani, Kunal B; Vos, Hendrik J; Abruzzo, Todd A; Haworth, Kevin J; Holland, Christy K 2019. Erratum to 'Effect of clot stiffness on recombinant tissue plasminogen activator lytic susceptibility in vitro' [Ultrasound Med Biol 44 (2018) 2710-2727]. Ultrasound in medicine & biology, 45 7, 1860Mercado-Shekhar, Karla P; Su, Haili; Kalaikadal, Deepak S; Lorenz, John N; Manglik, Raj M; Holland, Christy K; Redington, Andrew N; Haworth, Kevin J 2019. Acoustic droplet vaporization-mediated dissolved oxygen scavenging in blood-mimicking fluids, plasma, and blood. Ultrasonics sonochemistry, 56 , 114-124Shekhar, Himanshu; Kleven, Robert T; Peng, Tao; Palaniappan, Arunkumar; Karani, Kunal B; Huang, Shaoling; McPherson, David D; Holland, Christy K 2019. In vitro characterization of sonothrombolysis and echocontrast agents to treat ischemic stroke. Scientific reports, 9 1, 9902Shekhar, Himanshu; Palaniappan, Arunkumar; Peng, Tao; Lafond, Maxime; Moody, Melanie R; Haworth, Kevin J; Huang, Shaoling; McPherson, David D; Holland, Christy K 2019. Characterization and Imaging of Lipid-Shelled Microbubbles for Ultrasound-Triggered Release of Xenon. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 16 3, 878-890Lattwein, Kirby R; Shekhar, Himanshu; van Wamel, Willem J B; Gonzalez, Tammy; Herr, Andrew B; Holland, Christy K; Kooiman, Klazina 2018. An in vitro proof-of-principle study of sonobactericide. Scientific reports, 8 1, 3411Mercado-Shekhar, Karla P; Kleven, Robert T; Aponte Rivera, Hermes; Lewis, Ryden; Karani, Kunal B; Vos, Hendrik J; Abruzzo, Todd A; Haworth, Kevin J; Holland, Christy K 2018. Effect of Clot Stiffness on Recombinant Tissue Plasminogen Activator Lytic Susceptibility in Vitro. Ultrasound in medicine & biology, 44 12, 2710-2727Rich, Kyle T; Holland, Christy K; Rao, Marepalli B; Mast, T Douglas 2018. Characterization of cavitation-radiated acoustic power using diffraction correction. The Journal of the Acoustical Society of America, 144 6, 3563Shekhar, Himanshu; Smith, Nathaniel J; Raymond, Jason L; Holland, Christy K 2018. Effect of Temperature on the Size Distribution, Shell Properties, and Stability of Definity®. Ultrasound in medicine & biology, 44 2, 434-446Beigel, John H; Tebas, Pablo; Elie-Turenne, Marie-Carmelle; Bajwa, Ednan; Bell, Todd E; Cairns, Charles B; Shoham, Shmuel; Deville, Jaime G; Feucht, Eric; Feinberg, Judith; Luke, Thomas; Raviprakash, Kanakatte; Danko, Janine; O'Neil, Dorothy; Metcalf, Julia A; King, Karen; Burgess, Timothy H; Aga, Evgenia; Lane, H Clifford; Hughes, Michael D; Davey, Richard T 2017. Immune plasma for the treatment of severe influenza: an open-label, multicentre, phase 2 randomised study. The Lancet. Respiratory medicine, 5 6, 500-511Haworth, Kevin J; Goldstein, Bryan H; Mercado-Shekhar, Karla P; Srivastava, Rohan; Arunkumar, P; Su, Haili; Privitera, Ellena M; Holland, Christy K; Redington, Andrew N 2017. Dissolved Oxygen Scavenging by Acoustic Droplet Vaporization using Intravascular Ultrasound. IEEE International Ultrasonics Symposium : [proceedings]. IEEE International Ultrasonics Symposium, 2017 , Huang, Shenwen; Shekhar, Himanshu; Holland, Christy K 2017. Comparative lytic efficacy of rt-PA and ultrasound in porcine versus human clots. PloS one, 12 5, e0177786Shekhar, Himanshu; Bader, Kenneth B; Huang, Shenwen; Peng, Tao; Huang, Shaoling; McPherson, David D; Holland, Christy K 2017. In vitro thrombolytic efficacy of echogenic liposomes loaded with tissue plasminogen activator and octafluoropropane gas. Physics in medicine and biology, 62 2, 517-538Bader, Kenneth B; Bouchoux, Guillaume; Holland, Christy K 2016. Sonothrombolysis. Advances in experimental medicine and biology, 880 , 339-62Bader, Kenneth B; Crowe, Michael J; Raymond, Jason L; Holland, Christy K 2016. Effect of Frequency-Dependent Attenuation on Predicted Histotripsy Waveforms in Tissue-Mimicking Phantoms. Ultrasound in medicine & biology, 42 7, 1701-5Bader, Kenneth B; Haworth, Kevin J; Shekhar, Himanshu; Maxwell, Adam D; Peng, Tao; McPherson, David D; Holland, Christy K 2016. Efficacy of histotripsy combined with rt-PA in vitro. Physics in medicine and biology, 61 14, 5253-74Bader, Kenneth B; Holland, Christy K 2016. Predicting the growth of nanoscale nuclei by histotripsy pulses. Physics in medicine and biology, 61 7, 2947-66Haworth, Kevin J; Raymond, Jason L; Radhakrishnan, Kirthi; Moody, Melanie R; Huang, Shao-Ling; Peng, Tao; Shekhar, Himanshu; Klegerman, Melvin E; Kim, Hyunggun; McPherson, David D; Holland, Christy K 2016. Erratum to: "Trans-stent B-mode Ultrasound and Passive Cavitation Imaging" in Ultrasound Med Biol 2016;42(2):518-527. Ultrasound in medicine & biology, 42 5, 1244Haworth, Kevin J; Raymond, Jason L; Radhakrishnan, Kirthi; Moody, Melanie R; Huang, Shao-Ling; Peng, Tao; Shekhar, Himanshu; Klegerman, Melvin E; Kim, Hyunggun; McPherson, David D; Holland, Christy K 2016. Trans-Stent B-Mode Ultrasound and Passive Cavitation Imaging. Ultrasound in medicine & biology, 42 2, 518-27Kandadai, Madhuvanthi A; Mukherjee, Prithviraj; Shekhar, Himanshu; Shaw, George J; Papautsky, Ian; Holland, Christy K 2016. Microfluidic manufacture of rt-PA -loaded echogenic liposomes. Biomedical microdevices, 18 3, 48Klegerman, Melvin E; Naji, Ali K; Haworth, Kevin J; Zou, Yuejiao; Golunski, Eva; Peng, Tao; Britton, George L; Huang, Shao-Ling; Holland, Christy K; McPherson, David D 2016. Ultrasound-enhanced bevacizumab release from echogenic liposomes for inhibition of atheroma progression. Journal of liposome research, 26 1, 47-56Radhakrishnan, Kirthi; Holland, Christy K; Haworth, Kevin J 2016. Scavenging dissolved oxygen via acoustic droplet vaporization. Ultrasonics sonochemistry, 31 , 394-403Raymond, Jason L; Luan, Ying; Peng, Tao; Huang, Shao-Ling; McPherson, David D; Versluis, Michel; de Jong, Nico; Holland, Christy K 2016. Loss of gas from echogenic liposomes exposed to pulsed ultrasound. Physics in medicine and biology, 61 23, 8321-8339Sutton, J T; Haworth, K J; Shanmukhappa, S K; Moody, M R; Klegerman, M E; Griffin, J K; Patton, D M; McPherson, D D; Holland, C K 2016. Delivery of bevacizumab to atheromatous porcine carotid tissue using echogenic liposomes. Drug delivery, 23 9, 3594-3605Bader, Kenneth B; Bouchoux, Guillaume; Peng, Tao; Klegerman, Melvin E; McPherson, David D; Holland, Christy K 2015. Thrombolytic efficacy and enzymatic activity of rt-PA-loaded echogenic liposomes. Journal of thrombosis and thrombolysis, , Bader, Kenneth B; Gruber, Matthew J; Holland, Christy K 2015. Shaken and stirred: mechanisms of ultrasound-enhanced thrombolysis. Ultrasound in medicine & biology, 41 1, 187-96Haworth, Kevin J; Salgaonkar, Vasant A; Corregan, Nicholas M; Holland, Christy K; Mast, T Douglas 2015. Using Passive Cavitation Images to Classify High-Intensity Focused Ultrasound Lesions. Ultrasound in medicine & biology, 41 9, 2420-34Holland, C 2015. WE-D-210-03: Microbubble Pumps: Â Ultrasound Theragnostic Agents. Medical physics, 42 6, 3672Kandadai, Madhuvanthi A; Meunier, Jason M; Hart, Kimberley; Holland, Christy K; Shaw, George J 2015. Plasmin-loaded echogenic liposomes for ultrasound-mediated thrombolysis. Translational stroke research, 6 1, 78-87Radhakrishnan, Kirthi; Haworth, Kevin J; Peng, Tao; McPherson, David D; Holland, Christy K 2015. Loss of echogenicity and onset of cavitation from echogenic liposomes: pulse repetition frequency independence. Ultrasound in medicine & biology, 41 1, 208-21Raymond, Jason L; Luan, Ying; van Rooij, Tom; Kooiman, Klazina; Huang, Shao-Ling; McPherson, David D; Versluis, Michel; de Jong, Nico; Holland, Christy K 2015. Impulse response method for characterization of echogenic liposomes. The Journal of the Acoustical Society of America, 137 4, 1693-703Bouchoux, Guillaume; Shivashankar, Ravishankar; Abruzzo, Todd A; Holland, Christy K 2014. In silico study of low-frequency transcranial ultrasound fields in acute ischemic stroke patients. Ultrasound in medicine & biology, 40 6, 1154-66Gruber, Matthew J; Bader, Kenneth B; Holland, Christy K 2014. Cavitation thresholds of contrast agents in an in vitro human clot model exposed to 120-kHz ultrasound. The Journal of the Acoustical Society of America, 135 2, 646-53Haworth, Kevin J; Weidner, Christopher R; Abruzzo, Todd A; Shearn, Jason T; Holland, Christy K 2014. Mechanical properties and fibrin characteristics of endovascular coil-clot complexes: relevance to endovascular cerebral aneurysm repair paradigms. Journal of neurointerventional surgery, , Kim, Hyunggun; Britton, George L; Peng, Tao; Holland, Christy K; McPherson, David D; Huang, Shao-Ling 2014. Nitric oxide-loaded echogenic liposomes for treatment of vasospasm following subarachnoid hemorrhage. International journal of nanomedicine, 9 , 155-65Raymond, Jason L; Haworth, Kevin J; Bader, Kenneth B; Radhakrishnan, Kirthi; Griffin, Joseph K; Huang, Shao-Ling; McPherson, David D; Holland, Christy K 2014. Broadband attenuation measurements of phospholipid-shelled ultrasound contrast agents. Ultrasound in medicine & biology, 40 2, 410-21Sutton, J T; Raymond, J L; Verleye, M C; Pyne-Geithman, G J; Holland, C K 2014. Pulsed ultrasound enhances the delivery of nitric oxide from bubble liposomes to ex vivo porcine carotid tissue. International journal of nanomedicine, 9 , 4671-83Bader, K. B.; Holland, C. K. 2013. Gauging the likelihood of stable cavitation from ultrasound contrast agents Phys Med Biol, 58 1 , 127-44Bader, Kenneth B; Holland, Christy K 2013. Gauging the likelihood of stable cavitation from ultrasound contrast agents. Physics in medicine and biology, 58 1, 127-44Haworth, K. J.; Salgaonkar, V. A.; Corregan, N. M.; Holland, C. K.; Mast, T. D. 2013. Spatial specificity and sensitivity of passive cavitation imaging for monitoring high-intensity focused ultrasound thermal ablation in ex vivo bovine liver J Acoust Soc Am, 133 5 , 3263Kopechek, J. A.; Haworth, K. J.; Radhakrishnan, K.; Huang, S. L.; Klegerman, M. E.; McPherson, D. D.; Holland, C. K. 2013. The impact of bubbles on measurement of drug release from echogenic liposomes Ultrason Sonochem, 20 4 , 1121-30Kopechek, Jonathan A; Haworth, Kevin J; Radhakrishnan, Kirthi; Huang, Shao-Ling; Klegerman, Melvin E; McPherson, David D; Holland, Christy K 2013. The impact of bubbles on measurement of drug release from echogenic liposomes. Ultrasonics sonochemistry, 20 4, 1121-30Radhakrishnan, Kirthi; Bader, Kenneth B; Haworth, Kevin J; Kopechek, Jonathan A; Raymond, Jason L; Huang, Shao-Ling; McPherson, David D; Holland, Christy K 2013. Relationship between cavitation and loss of echogenicity from ultrasound contrast agents. Physics in medicine and biology, 58 18, 6541-63Sutton, J. T.; Ivancevich, N. M.; Perrin, S. R., Jr.; Vela, D. C.; Holland, C. K. 2013. Clot retraction affects the extent of ultrasound-enhanced thrombolysis in an ex vivo porcine thrombosis model Ultrasound Med Biol, 39 5 , 813-24Sutton, J. T.; Haworth, K. J.; Pyne-Geithman, G.; Holland, C. K. 2013. Ultrasound-mediated drug delivery for cardiovascular disease Expert Opin Drug Deliv, 10 5 , 573-92Sutton, Jonathan T; Haworth, Kevin J; Pyne-Geithman, Gail; Holland, Christy K 2013. Ultrasound-mediated drug delivery for cardiovascular disease. Expert opinion on drug delivery, 10 5, 573-92Sutton, Jonathan T; Ivancevich, Nikolas M; Perrin, Stephen R; Vela, Deborah C; Holland, Christy K 2013. Clot retraction affects the extent of ultrasound-enhanced thrombolysis in an ex vivo porcine thrombosis model. Ultrasound in medicine & biology, 39 5, 813-24Bouchoux, G.; Bader, K. B.; Korfhagen, J. J.; Raymond, J. L.; Shivashankar, R.; Abruzzo, T. A.; Holland, C. K. 2012. Experimental validation of a finite-difference model for the prediction of transcranial ultrasound fields based on CT images Phys Med Biol, 57 23 , 8005-22Bouchoux, Guillaume; Bader, Kenneth B; Korfhagen, Joseph J; Raymond, Jason L; Shivashankar, Ravishankar; Abruzzo, Todd A; Holland, Christy K 2012. Experimental validation of a finite-difference model for the prediction of transcranial ultrasound fields based on CT images. Physics in medicine and biology, 57 23, 8005-22Haworth, K. J.; Mast, T. D.; Radhakrishnan, K.; Burgess, M. T.; Kopechek, J. A.; Huang, S. L.; McPherson, D. D.; Holland, C. K. 2012. Passive imaging with pulsed ultrasound insonations J Acoust Soc Am, 132 1 , 544-53Haworth, Kevin J; Mast, T Douglas; Radhakrishnan, Kirthi; Burgess, Mark T; Kopechek, Jonathan A; Huang, Shao-Ling; McPherson, David D; Holland, Christy K 2012. Passive imaging with pulsed ultrasound insonations. The Journal of the Acoustical Society of America, 132 1, 544-53Huppert, Jill S; Reed, Jennifer L; Munafo, Jennifer Knopf; Ekstrand, Rachel; Gillespie, Gordon; Holland, Carolyn; Britto, Maria T 2012. Improving notification of sexually transmitted infections: a quality improvement project and planned experiment. Pediatrics, 130 2, e415-22Laing, S. T.; Moody, M. R.; Kim, H.; Smulevitz, B.; Huang, S. L.; Holland, C. K.; McPherson, D. D.; Klegerman, M. E. 2012. Thrombolytic efficacy of tissue plasminogen activator-loaded echogenic liposomes in a rabbit thrombus model Thromb Res, 130 4 , 629-35Radhakrishnan, K.; Haworth, K. J.; Huang, S. L.; Klegerman, M. E.; McPherson, D. D.; Holland, C. K. 2012. Stability of echogenic liposomes as a blood pool ultrasound contrast agent in a physiologic flow phantom Ultrasound Med Biol, 38 11 , 1970-81Radhakrishnan, Kirthi; Haworth, Kevin J; Huang, Shao-Ling; Klegerman, Melvin E; McPherson, David D; Holland, Christy K 2012. Stability of echogenic liposomes as a blood pool ultrasound contrast agent in a physiologic flow phantom. Ultrasound in medicine & biology, 38 11, 1970-81Hitchcock, K. E.; Ivancevich, N. M.; Haworth, K. J.; Caudell Stamper, D. N.; Vela, D. C.; Sutton, J. T.; Pyne-Geithman, G. J.; Holland, C. K. 2011. Ultrasound-enhanced rt-PA thrombolysis in an ex vivo porcine carotid artery model Ultrasound Med Biol, 37 8 , 1240-51Hitchcock, Kathryn E; Ivancevich, Nikolas M; Haworth, Kevin J; Caudell Stamper, Danielle N; Vela, Deborah C; Sutton, Jonathan T; Pyne-Geithman, Gail J; Holland, Christy K 2011. Ultrasound-enhanced rt-PA thrombolysis in an ex vivo porcine carotid artery model. Ultrasound in medicine & biology, 37 8, 1240-51Kopechek, J. A.; Haworth, K. J.; Raymond, J. L.; Douglas Mast, T.; Perrin, S. R.; Klegerman, M. E.; Huang, S.; Porter, T. M.; McPherson, D. D.; Holland, C. K. 2011. Acoustic characterization of echogenic liposomes: frequency-dependent attenuation and backscatter J Acoust Soc Am, 130 5 , 3472-81Kopechek, Jonathan A; Haworth, Kevin J; Raymond, Jason L; Douglas Mast, T; Perrin, Stephen R; Klegerman, Melvin E; Huang, Shaoling; Porter, Tyrone M; McPherson, David D; Holland, Christy K 2011. Acoustic characterization of echogenic liposomes: frequency-dependent attenuation and backscatter. The Journal of the Acoustical Society of America, 130 5, 3472-81Laing, S. T.; Moody, M.; Smulevitz, B.; Kim, H.; Kee, P.; Huang, S.; Holland, C. K.; McPherson, D. D. 2011. Ultrasound-enhanced thrombolytic effect of tissue plasminogen activator-loaded echogenic liposomes in an in vivo rabbit aorta thrombus model--brief report Arterioscler Thromb Vasc Biol, 31 6 , 1357-9Meunier, J. M.; Holland, C. K.; Porter, T. M.; Lindsell, C. J.; Shaw, G. J. 2011. Combination treatment with rt-PA is more effective than rt-PA alone in an in vitro human clot model Curr Neurovasc Res, 8 4 , 305-12Meunier, Jason M; Holland, Christy K; Porter, Tyrone M; Lindsell, Christopher J; Shaw, George J 2011. Combination treatment with rt-PA is more effective than rt-PA alone in an in vitro human clot model. Current neurovascular research, 8 4, 305-12Britton, G. L.; Kim, H.; Kee, P. H.; Aronowski, J.; Holland, C. K.; McPherson, D. D.; Huang, S. L. 2010. In vivo therapeutic gas delivery for neuroprotection with echogenic liposomes Circulation, 122 16 , 1578-87Herbst, S. M.; Klegerman, M. E.; Kim, H.; Qi, J.; Shelat, H.; Wassler, M.; Moody, M. R.; Yang, C. M.; Ge, X.; Zou, Y.; Kopechek, J. A.; Clubb, F. J.; Kraemer, D. C.; Huang, S.; Holland, C. K.; McPherson, D. D.; Geng, Y. J. 2010. Delivery of stem cells to porcine arterial wall with echogenic liposomes conjugated to antibodies against CD34 and intercellular adhesion molecule-1 Mol Pharm, 7 1 , 3-11Hitchcock, K. E.; Caudell, D. N.; Sutton, J. T.; Klegerman, M. E.; Vela, D.; Pyne-Geithman, G. J.; Abruzzo, T.; Cyr, P. E.; Geng, Y. J.; McPherson, D. D.; Holland, C. K. 2010. Ultrasound-enhanced delivery of targeted echogenic liposomes in a novel ex vivo mouse aorta model J Control Release, 144 3 , 288-95Hitchcock, K. E.; Holland, C. K. 2010. Ultrasound-assisted thrombolysis for stroke therapy: better thrombus break-up with bubbles Stroke, 41 10 Suppl , S50-3Hitchcock, Kathryn E; Caudell, Danielle N; Sutton, Jonathan T; Klegerman, Melvin E; Vela, Deborah; Pyne-Geithman, Gail J; Abruzzo, Todd; Cyr, Peppar E P; Geng, Yong-Jian; McPherson, David D; Holland, Christy K 2010. Ultrasound-enhanced delivery of targeted echogenic liposomes in a novel ex vivo mouse aorta model. Journal of controlled release : official journal of the Controlled Release Society, 144 3, 288-95Hitchcock, Kathryn E; Holland, Christy K 2010. Ultrasound-assisted thrombolysis for stroke therapy: better thrombus break-up with bubbles. Stroke; a journal of cerebral circulation, 41 10 Suppl, S50-3Klegerman, M. E.; Wassler, M.; Huang, S. L.; Zou, Y.; Kim, H.; Shelat, H. S.; Holland, C. K.; Geng, Y. J.; McPherson, D. D. 2010. Liposomal modular complexes for simultaneous targeted delivery of bioactive gases and therapeutics J Control Release, 142 3 , 326-31Kopechek, J. A.; Kim, H.; McPherson, D. D.; Holland, C. K. 2010. Calibration of the 1-MHz Sonitron ultrasound system Ultrasound Med Biol, 36 10 , 1762-6Kopechek, Jonathan A; Kim, Hyunggun; McPherson, David D; Holland, Christy K 2010. Calibration of the 1-MHz Sonitron ultrasound system. Ultrasound in medicine & biology, 36 10, 1762-6Laing, S. T.; Kim, H.; Kopechek, J. A.; Parikh, D.; Huang, S.; Klegerman, M. E.; Holland, C. K.; McPherson, D. D. 2010. Ultrasound-mediated delivery of echogenic immunoliposomes to porcine vascular smooth muscle cells in vivo J Liposome Res, 20 2 , 160-7Shaw, G. J.; Meunier, J. M.; Lindsell, C. J.; Pancioli, A. M.; Holland, C. K. 2010. Making the right choice: optimizing rt-PA and eptifibatide lysis, an in vitro study Thromb Res, 126 4 , e305-11Shaw, George J; Meunier, Jason M; Lindsell, Christopher J; Pancioli, Arthur M; Holland, Christy K 2010. Making the right choice: optimizing rt-PA and eptifibatide lysis, an in vitro study. Thrombosis research, 126 4, e305-11Smith, D. A.; Vaidya, S. S.; Kopechek, J. A.; Huang, S. L.; Klegerman, M. E.; McPherson, D. D.; Holland, C. K. 2010. Ultrasound-triggered release of recombinant tissue-type plasminogen activator from echogenic liposomes Ultrasound Med Biol, 36 1 , 145-57Smith, Denise A B; Vaidya, Sampada S; Kopechek, Jonathan A; Huang, Shao-Ling; Klegerman, Melvin E; McPherson, David D; Holland, Christy K 2010. Ultrasound-triggered release of recombinant tissue-type plasminogen activator from echogenic liposomes. Ultrasound in medicine & biology, 36 1, 145-57Holland, C. K.; McPherson, D. D. 2009. Echogenic Lipsomes for Targeted Drug Delivery Proc IEEE Int Symp Biomed Imaging, 2009 3 , 755-758Holland, Christy K; McPherson, David D 2009. ECHOGENIC LIPSOMES FOR TARGETED DRUG DELIVERY. Proceedings / IEEE International Symposium on Biomedical Imaging: from nano to macro. IEEE International Symposium on Biomedical Imaging, 2009 , 755-758Meunier, J. M.; Holland, C. K.; Pancioli, A. M.; Lindsell, C. J.; Shaw, G. J. 2009. Effect of low frequency ultrasound on combined rt-PA and eptifibatide thrombolysis in human clots Thromb Res, 123 3 , 528-36Meunier, Jason M; Holland, Christy K; Pancioli, Arthur M; Lindsell, Christopher J; Shaw, George J 2009. Effect of low frequency ultrasound on combined rt-PA and eptifibatide thrombolysis in human clots. Thrombosis research, 123 3, 528-36Salgaonkar, V. A.; Datta, S.; Holland, C. K.; Mast, T. D. 2009. Passive cavitation imaging with ultrasound arrays J Acoust Soc Am, 126 6 , 3071-83Salgaonkar, Vasant A; Datta, Saurabh; Holland, Christy K; Mast, T Douglas 2009. Passive cavitation imaging with ultrasound arrays. The Journal of the Acoustical Society of America, 126 6, 3071-83Shaw, G. J.; Meunier, J. M.; Huang, S. L.; Lindsell, C. J.; McPherson, D. D.; Holland, C. K. 2009. Ultrasound-enhanced thrombolysis with tPA-loaded echogenic liposomes Thromb Res, 124 3 , 306-10Shaw, George J; Meunier, Jason M; Huang, Shao-Ling; Lindsell, Christopher J; McPherson, David D; Holland, Christy K 2009. Ultrasound-enhanced thrombolysis with tPA-loaded echogenic liposomes. Thrombosis research, 124 3, 306-10Ammi, A. Y.; Mast, T. D.; Huang, I. H.; Abruzzo, T. A.; Coussios, C. C.; Shaw, G. J.; Holland, C. K. 2008. Characterization of ultrasound propagation through ex-vivo human temporal bone Ultrasound Med Biol, 34 10 , 1578-89Ammi, Azzdine Y; Mast, T Douglas; Huang, I-Hua; Abruzzo, Todd A; Coussios, Constantin-C; Shaw, George J; Holland, Christy K 2008. Characterization of ultrasound propagation through ex-vivo human temporal bone. Ultrasound in medicine & biology, 34 10, 1578-89Datta, S.; Coussios, C. C.; Ammi, A. Y.; Mast, T. D.; de Courten-Myers, G. M.; Holland, C. K. 2008. Ultrasound-enhanced thrombolysis using Definity as a cavitation nucleation agent Ultrasound Med Biol, 34 9 , 1421-33Datta, Saurabh; Coussios, Constantin-C; Ammi, Azzdine Y; Mast, T Douglas; de Courten-Myers, Gabrielle M; Holland, Christy K 2008. Ultrasound-enhanced thrombolysis using Definity as a cavitation nucleation agent. Ultrasound in medicine & biology, 34 9, 1421-33Holland, C. K.; Vaidya, S. S.; Datta, S.; Coussios, C. C.; Shaw, G. J. 2008. Ultrasound-enhanced tissue plasminogen activator thrombolysis in an in vitro porcine clot model Thromb Res, 121 5 , 663-73Holland, Christy K; Vaidya, Sampada S; Datta, Saurabh; Coussios, Constantin-C; Shaw, George J 2008. Ultrasound-enhanced tissue plasminogen activator thrombolysis in an in vitro porcine clot model. Thrombosis research, 121 5, 663-73Kee, P. H.; Abruzzo, T. A.; Smith, D. A.; Kopechek, J. A.; Wang, B.; Huang, S. L.; MacDonald, R. C.; Holland, C. K.; McPherson, D. D. 2008. Synthesis, acoustic stability, and pharmacologic activities of papaverine-loaded echogenic liposomes for ultrasound controlled drug delivery J Liposome Res, 18 4 , 263-77Kopechek, J. A.; Abruzzo, T. M.; Wang, B.; Chrzanowski, S. M.; Smith, D. A.; Kee, P. H.; Huang, S.; Collier, J. H.; McPherson, D. D.; Holland, C. K. 2008. Ultrasound-mediated release of hydrophilic and lipophilic agents from echogenic liposomes J Ultrasound Med, 27 11 , 1597-606Kopechek, Jonathan A; Abruzzo, Todd M; Wang, Boyu; Chrzanowski, Stephen M; Smith, Denise A B; Kee, Patrick H; Huang, Shaoling; Collier, Joel H; McPherson, David D; Holland, Christy K 2008. Ultrasound-mediated release of hydrophilic and lipophilic agents from echogenic liposomes. Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 27 11, 1597-606Mast, T Douglas; Salgaonkar, Vasant A; Karunakaran, Chandrapriya; Besse, John A; Datta, Saurabh; Holland, Christy K 2008. Acoustic emissions during 3.1 MHz ultrasound bulk ablation in vitro. Ultrasound in medicine & biology, 34 9, 1434-48Mast, T. D.; Salgaonkar, V. A.; Karunakaran, C.; Besse, J. A.; Datta, S.; Holland, C. K. 2008. Acoustic emissions during 3.1 MHz ultrasound bulk ablation in vitro Ultrasound Med Biol, 34 9 , 1434-48Miller, D. L.; Averkiou, M. A.; Brayman, A. A.; Everbach, E. C.; Holland, C. K.; Wible, J. H., Jr.; Wu, J. 2008. Bioeffects considerations for diagnostic ultrasound contrast agents J Ultrasound Med, 27 4 , 611-32; quiz 633-6Shaw, G. J.; Meunier, J. M.; Lindsell, C. J.; Holland, C. K. 2008. Tissue plasminogen activator concentration dependence of 120 kHz ultrasound-enhanced thrombolysis Ultrasound Med Biol, 34 11 , 1783-92Shaw, George J; Meunier, Jason M; Lindsell, Christopher J; Holland, Christy K 2008. Tissue plasminogen activator concentration dependence of 120 kHz ultrasound-enhanced thrombolysis. Ultrasound in medicine & biology, 34 11, 1783-92Wang, Y.; Krishnamoorthy, M.; Banerjee, R.; Zhang, J.; Rudich, S.; Holland, C.; Arend, L.; Roy-Chaudhury, P. 2008. Venous stenosis in a pig arteriovenous fistula model--anatomy, mechanisms and cellular phenotypes Nephrol Dial Transplant, 23 2 , 525-33Wang, Yang; Krishnamoorthy, Mahesh; Banerjee, Rupak; Zhang, Jianhua; Rudich, Steven; Holland, Christy; Arend, Lois; Roy-Chaudhury, Prabir 2008. Venous stenosis in a pig arteriovenous fistula model--anatomy, mechanisms and cellular phenotypes. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 23 2, 525-33Zhou, X.; Espy-Wilson, C. Y.; Boyce, S.; Tiede, M.; Holland, C.; Choe, A. 2008. A magnetic resonance imaging-based articulatory and acoustic study of "retroflex" and "bunched" American English /r J Acoust Soc Am, 123 6 , 4466-81Meunier, J. M.; Holland, C. K.; Lindsell, C. J.; Shaw, G. J. 2007. Duty cycle dependence of ultrasound enhanced thrombolysis in a human clot model Ultrasound Med Biol, 33 4 , 576-83Meunier, Jason M; Holland, Christy K; Lindsell, Christopher J; Shaw, George J 2007. Duty cycle dependence of ultrasound enhanced thrombolysis in a human clot model. Ultrasound in medicine & biology, 33 4, 576-83Nahirnyak, V.; Mast, T. D.; Holland, C. K. 2007. Ultrasound-induced thermal elevation in clotted blood and cranial bone Ultrasound Med Biol, 33 8 , 1285-95Nahirnyak, Volodymyr; Mast, T Douglas; Holland, Christy K 2007. Ultrasound-induced thermal elevation in clotted blood and cranial bone. Ultrasound in medicine & biology, 33 8, 1285-95Shaw, G. J.; Dhamija, A.; Bavani, N.; Wagner, K. R.; Holland, C. K. 2007. Arrhenius temperature dependence of in vitro tissue plasminogen activator thrombolysis Phys Med Biol, 52 11 , 2953-67Shaw, George J; Dhamija, Ashima; Bavani, Nazli; Wagner, Kenneth R; Holland, Christy K 2007. Arrhenius temperature dependence of in vitro tissue plasminogen activator thrombolysis. Physics in medicine and biology, 52 11, 2953-67Smith, D. A.; Porter, T. M.; Martinez, J.; Huang, S.; MacDonald, R. C.; McPherson, D. D.; Holland, C. K. 2007. Destruction thresholds of echogenic liposomes with clinical diagnostic ultrasound Ultrasound Med Biol, 33 5 , 797-809Smith, Denise A B; Porter, Tyrone M; Martinez, Janet; Huang, Shaoling; MacDonald, Robert C; McPherson, David D; Holland, Christy K 2007. Destruction thresholds of echogenic liposomes with clinical diagnostic ultrasound. Ultrasound in medicine & biology, 33 5, 797-809Tiukinhoy-Laing, S. D.; Huang, S.; Klegerman, M.; Holland, C. K.; McPherson, D. D. 2007. Ultrasound-facilitated thrombolysis using tissue-plasminogen activator-loaded echogenic liposomes Thromb Res, 119 6 , 777-84Datta, S.; Coussios, C. C.; McAdory, L. E.; Tan, J.; Porter, T.; De Courten-Myers, G.; Holland, C. K. 2006. Correlation of cavitation with ultrasound enhancement of thrombolysis Ultrasound Med Biol, 32 8 , 1257-67Datta, Saurabh; Coussios, Constantin-C; McAdory, Louis E; Tan, Jun; Porter, Tyrone; De Courten-Myers, Gabrielle; Holland, Christy K 2006. Correlation of cavitation with ultrasound enhancement of thrombolysis. Ultrasound in medicine & biology, 32 8, 1257-67More, S. R.; Lim, T. C.; Li, M.; Holland, C. K.; Boyce, S. E.; Lee, J. H. 2006. Acoustic noise characteristics of a 4 Telsa MRI scanner J Magn Reson Imaging, 23 3 , 388-97More, Shashikant R; Lim, Teik C; Li, Mingfeng; Holland, Christy K; Boyce, Suzanne E; Lee, Jing-Huei 2006. Acoustic noise characteristics of a 4 Telsa MRI scanner. Journal of magnetic resonance imaging : JMRI, 23 3, 388-97Nahirnyak, V. M.; Yoon, S. W.; Holland, C. K. 2006. Acousto-mechanical and thermal properties of clotted blood J Acoust Soc Am, 119 6 , 3766-72Nahirnyak, Volodymyr M; Yoon, Suk Wang; Holland, Christy K 2006. Acousto-mechanical and thermal properties of clotted blood. The Journal of the Acoustical Society of America, 119 6, 3766-72Porter, T. M.; Smith, D. A.; Holland, C. K. 2006. Acoustic techniques for assessing the Optison destruction threshold J Ultrasound Med, 25 12 , 1519-29Porter, Tyrone M; Smith, Denise A B; Holland, Christy K 2006. Acoustic techniques for assessing the Optison destruction threshold. Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 25 12, 1519-29Wright, S. W.; Lindsell, C. J.; Hinckley, W. R.; Williams, A.; Holland, C.; Lewis, C. H.; Heimburger, G. 2006. High fidelity medical simulation in the difficult environment of a helicopter: feasibility, self-efficacy and cost BMC Med Educ, 6 4 , 49Wright, Stewart W; Lindsell, Christopher J; Hinckley, William R; Williams, Annette; Holland, Carolyn; Lewis, Christopher H; Heimburger, Gail 2006. High fidelity medical simulation in the difficult environment of a helicopter: feasibility, self-efficacy and cost. BMC medical education, 6 , 49Cheng, J. Y.; Shaw, G. J.; Holland, C. K. 2005. In vitro microscopic imaging of enhanced thrombolysis with 120-kHz ultrasound in a human clot model Acoust Res Lett Online, 6 1 , 25-29Cheng, Jason Y; Shaw, George J; Holland, Christy K 2005. In vitro microscopic imaging of enhanced thrombolysis with 120-kHz ultrasound in a human clot model. Acoustics research letters online : ARLO, 6 1, 25-29Coussios, C. C.; Holland, C. K.; Jakubowska, L.; Huang, S. L.; MacDonald, R. C.; Nagaraj, A.; McPherson, D. D. 2004. In vitro characterization of liposomes and Optison by acoustic scattering at 3.5 MHz Ultrasound Med Biol, 30 2 , 181-90Coussios, Constantin-C; Holland, Christy K; Jakubowska, Ludwika; Huang, Shao-Ling; MacDonald, Robert C; Nagaraj, Ashwin; McPherson, David D 2004. In vitro characterization of liposomes and Optison by acoustic scattering at 3.5 MHz. Ultrasound in medicine & biology, 30 2, 181-90McPherson, D. D.; Holland, C. K. 2003. Seizing the science of ultrasound: beyond imaging and into physiology and therapeutics J Am Coll Cardiol, 41 9 , 1628-30Taylor, C. R.; Holland, C. K. 2003. Kenneth J. Taylor, MD, PhD, FACP, 1939-2003, pioneer of diagnostic ultrasound imaging J Ultrasound Med, 22 6 , 663-4Fowlkes, J. B.; Holland, C. K. 2000. Mechanical bioeffects from diagnostic ultrasound: AIUM consensus statements. American Institute of Ultrasound in Medicine J Ultrasound Med, 19 2 , 69-72Ouanounou, S.; Tomsick, T. A.; Heitsman, C.; Holland, C. K. 1999. Cavernous sinus and inferior petrosal sinus flow signal on three-dimensional time-of-flight MR angiography AJNR Am J Neuroradiol, 20 8 , 1476-81Ouanounou, S; Tomsick, T A; Heitsman, C; Holland, C K 1999. Cavernous sinus and inferior petrosal sinus flow signal on three-dimensional time-of-flight MR angiography. AJNR. American journal of neuroradiology, 20 8, 1476-81Holland, C K; Brown, J M; Scoutt, L M; Taylor, K J 1998. Lower extremity volumetric arterial blood flow in normal subjects. Ultrasound in medicine & biology, 24 8, 1079-86Holland, C. K.; Brown, J. M.; Scoutt, L. M.; Taylor, K. J. 1998. Lower extremity volumetric arterial blood flow in normal subjects Ultrasound Med Biol, 24 8 , 1079-86Deng, C. X.; Xu, Q.; Apfel, R. E.; Holland, C. K. 1996. In vitro measurements of inertial cavitation thresholds in human blood Ultrasound Med Biol, 22 7 , 939-48Deng, C. X.; Xu, Q.; Apfel, R. E.; Holland, C. K. 1996. Inertial cavitation produced by pulsed ultrasound in controlled host media J Acoust Soc Am, 100 2 Pt 1 , 1199-208Holland, C K; Clancy, M J; Taylor, K J; Alderman, J L; Purushothaman, K; McCauley, T R 1996. Volumetric flow estimation in vivo and in vitro using pulsed-Doppler ultrasound. Ultrasound in medicine & biology, 22 5, 591-603Holland, C K; Deng, C X; Apfel, R E; Alderman, J L; Fernandez, L A; Taylor, K J 1996. Direct evidence of cavitation in vivo from diagnostic ultrasound. Ultrasound in medicine & biology, 22 7, 917-25Holland, C. K.; Clancy, M. J.; Taylor, K. J.; Alderman, J. L.; Purushothaman, K.; McCauley, T. R. 1996. Volumetric flow estimation in vivo and in vitro using pulsed-Doppler ultrasound Ultrasound Med Biol, 22 5 , 591-603Holland, C. K.; Deng, C. X.; Apfel, R. E.; Alderman, J. L.; Fernandez, L. A.; Taylor, K. J. 1996. Direct evidence of cavitation in vivo from diagnostic ultrasound Ultrasound Med Biol, 22 7 , 917-25Brown, J. M.; Hammers, L. W.; Barton, J. W.; Holland, C. K.; Scoutt, L. M.; Pellerito, J. S.; Taylor, K. J. 1995. Quantitative Doppler assessment of acute scrotal inflammation Radiology, 197 2 , 427-31McCauley, T. R.; Pena, C. S.; Holland, C. K.; Price, T. B.; Gore, J. C. 1995. Validation of volume flow measurements with cine phase-contrast MR imaging for peripheral arterial waveforms J Magn Reson Imaging, 5 6 , 663-8Reinhold, C.; Hammers, L.; Taylor, C. R.; Quedens-Case, C. L.; Holland, C. K.; Taylor, K. J. 1995. Characterization of focal hepatic lesions with duplex sonography: findings in 198 patients AJR Am J Roentgenol, 164 5 , 1131-5Dillon, E. H.; Case, C. Q.; Ramos, I. M.; Holland, C. K.; Taylor, K. J. 1993. Endovaginal pulsed and color Doppler in first-trimester pregnancy Ultrasound Med Biol, 19 7 , 517-25Dillon, E. H.; Case, C. Q.; Ramos, I. M.; Holland, C. K.; Taylor, K. J. 1993. Endovaginal US and Doppler findings after first-trimester abortion Radiology, 186 1 , 87-91Holland, C. K. 1993. An ethnographic study of nursing culture as an exploration for determining the existence of a system of ritual J Adv Nurs, 18 9 , 1461-70Holland, C. K.; Taylor, K. J. 1993. Blood flow quantitation: waveform analysis, volume measurement, tumor flow, and the role of color imaging Clin Diagn Ultrasound, 28 2 , 125-39Crum, L. A.; Roy, R. A.; Dinno, M. A.; Church, C. C.; Apfel, R. E.; Holland, C. K.; Madanshetty, S. I. 1992. Acoustic cavitation produced by microsecond pulses of ultrasound: a discussion of some selected results J Acoust Soc Am, 91 2 , 1113-9Holland, C. K.; Roy, R. A.; Apfel, R. E.; Crum, L. A. 1992. In vitro detection of cavitation induced by a diagnostic ultrasound system IEEE Trans Ultrason Ferroelectr Freq Control, 39 1 , 95-101Apfel, R. E.; Holland, C. K. 1991. Gauging the likelihood of cavitation from short-pulse, low-duty cycle diagnostic ultrasound Ultrasound Med Biol, 17 2 , 179-85Holland, C. K.; Apfel, R. E. 1990. Thresholds for transient cavitation produced by pulsed ultrasound in a controlled nuclei environment J Acoust Soc Am, 88 5 , 2059-69Holland, C. K.; Apfel, R. E. 1989. An improved theory for the prediction of microcavitation thresholds IEEE Trans Ultrason Ferroelectr Freq Control, 36 2 , 204-8Atchley, A. A.; Frizzell, L. A.; Apfel, R. E.; Holland, C. K.; Madanshetty, S.; Roy, R. A. 1988. Thresholds for cavitation produced in water by pulsed ultrasound Ultrasonics, 26 5 , 280-5Lattwein K.;Shekhar H.;Van Wamel W.;Gonzalez T.;Herr A.;Holland C.;Kooiman K. 12-01-2018. An in vitro proof-of-principle study of sonobactericide Scientific Reports, 8 1, Krishnamoorthy M.K.;Roy-Chaudhury P.;Wang Y.;Holland C.K.;Rigger D.;Choe A.;Banerjee R.K. 12-01-2009. Vascular remodeling of arteriovenous fistula Proceedings of the ASME Summer Bioengineering Conference 2009, SBC2009, PART B, 1077-1078Kee P.;Abruzzo T.;Smith D.;Kopechek J.;Wang B.;Huang S.;MacDonald R.;Holland C.;McPherson D. 12-01-2008. Synthesis, acoustic stability, and pharmacologic activities of papaverine-loaded echogenic liposomes Journal of Liposome Research, 18 4, 263-277Holland C.;McPherson D. 11-17-2009. Echogenic lipsomes for targeted drug delivery Proceedings - 2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2009, , 755-758Haworth K.;Goldstein B.;Mercado-Shekhar K.;Holland C.;Redington A. 10-31-2017. Dissolved oxygen scavenging by acoustic droplet vaporization using intravascular ultrasound IEEE International Ultrasonics Symposium, IUS, , Haworth K.J.;Arunkumar P.;Goldstein B.H.;Su H.;Mercado-Shekhar K.P.;Privitera E.M.;Srivastava R.;Holland C.K.;Redington A.N. 10-31-2017. Dissolved oxygen scavenging by acoustic droplet vaporization using intravascular ultrasound IEEE International Ultrasonics Symposium, IUS, , Bader K.;Holland C. 10-28-2015. Development of a hybrid finite difference solution of the Westervelt equation using the fast nearfie AIP Conference Proceedings, 1685 , Britton G.;Kim H.;Kee P.;Aronowski J.;Holland C.;McPherson D.;Huang S. 10-19-2010. In vivo therapeutic gas delivery for neuroprotection with echogenic liposomes Circulation, 122 16, 1578-1587 Holland C.K.; Shekhar H.; Lafond M. 10-01-2019. Lipid-shelled microbubbles for ultrasound-triggered release of bioactive gases to treat stroke and c IEEE International Ultrasonics Symposium, IUS, 2019-October , 2037-2039Laing S.;Moody M.;Kim H.;Smulevitz B.;Huang S.;Holland C.;McPherson D.;Klegerman M. 10-01-2012. Thrombolytic efficacy of tissue plasminogen activator-loaded echogenic liposomes in a rabbit thrombu Thrombosis Research, 130 4, 629-635Mast T.;Salgaonkar V.;Karunakaran C.;Besse J.;Datta S.;Holland C. 09-24-2007. Measurements of cavitation dose, echogenicity, and temperature during ultrasound ablation AIP Conference Proceedings, 911 , 335-341 Hendley S.A.; Paul J.D.; Maxwell A.D.; Haworth K.J.; Holland C.K.; Bader K.B. 09-01-2021. Clot Degradation Under the Action of Histotripsy Bubble Activity and a Lytic Drug IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 68 9, 2942-2952Salgaonkar V.;Karunakaran C.;Besse J.;Heinlein G.;Datta S.;Holland C.;Mast T. 08-31-2007. Image-guided Ex vivo liver ablation by unfocused ultrasound using passive cavitation detection Progress in Biomedical Optics and Imaging - Proceedings of SPIE, 6440 , Karunakaran C.;Burgess M.;Holland C.;Mast T. 07-21-2009. Role of cavitation in bulk ultrasound ablation: A histologic study AIP Conference Proceedings, 1113 , 43-47Salgaonkar V.;Datta S.;Holland C.;Masta T. 07-21-2009. Passive imaging of cavitational acoustic emissions with ultrasound arrays AIP Conference Proceedings, 1113 , 73-77Cheng J.;Shaw G.;Holland C. 07-01-2005. In vitro microscopic imaging of enhanced thrombolysis with 120-kHz ultrasound in a human clot model Acoustic Research Letters Online, 6 3, 25-29Haworth K.;Salgaonkar V.;Corregan N.;Holland C.;Mast T. 06-19-2013. Spatial specificity and sensitivity of passive cavitation imaging for monitoring high-intensity focu Proceedings of Meetings on Acoustics, 19 , Zhou X.;Espy-Wilson C.Y.;Boyce S.;Tiede M.;Holland C.;Choe A. 06-17-2008. A magnetic resonance imaging-based articulatory and acoustic study of "retroflex" and "bunched" Amer Journal of the Acoustical Society of America, 123 6, 4466-4481 Haworth K.J.; Salido N.G.; Lafond M.; Escudero D.S.; Holland C.K. 06-01-2023. Passive Cavitation Imaging Artifact Reduction Using Data-Adaptive Spatial Filtering IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 70 6, 498-509Laing S.;Moody M.;Smulevitz B.;Kim H.;Kee P.;Huang S.;Holland C.;McPherson D. 06-01-2011. Ultrasound-enhanced thrombolytic effect of tissue plasminogen activator-loaded echogenic liposomes i Arteriosclerosis, Thrombosis, and Vascular Biology, 31 6, 1357-1359Laing S.;Kim H.;Kopechek J.;Parikh D.;Huang S.;Klegerman M.;Holland C.;McPherson D. 06-01-2010. Ultrasound-mediated delivery of echogenic immunoliposomes to porcine vascular smooth muscle cells in Journal of Liposome Research, 20 2, 160-167McPherson D.;Holland C. 05-07-2003. Seizing the science of ultrasound: Beyond imaging and into physiology and therapeutics Journal of the American College of Cardiology, 41 9, 1628-1630Haworth K.;Raymond J.;Radhakrishnan K.;Moody M.;Huang S.;Peng T.;Shekhar H.;Klegerman M.;Kim H.;McPherson D.;Holland C. 05-01-2016. Erratum to: "Trans-stent B-mode Ultrasound and Passive Cavitation Imaging" in Ultrasound Med Biol 20 Ultrasound in Medicine and Biology, 42 5, 1244Holland C. 04-01-2016. ACOUSTICAL NEWS-USA Journal of the Acoustical Society of America, 139 4, Tiukinhoy-Laing S.;Huang S.;Klegerman M.;Holland C.;McPherson D. 03-23-2007. Ultrasound-facilitated thrombolysis using tissue-plasminogen activator-loaded echogenic liposomes Thrombosis Research, 119 6, 777-784Klegerman M.;Wassler M.;Huang S.;Zou Y.;Kim H.;Shelat H.;Holland C.;Geng Y.;McPherson D. 03-19-2010. Liposomal modular complexes for simultaneous targeted delivery of bioactive gases and therapeutics Journal of Controlled Release, 142 3, 326-331Toepfer N.;Racadio J.;Adams J.;Babcock D.;Holland C. 03-01-2006. Aortic pseudothrombus: A sonographic artifact in the abdominal aorta Journal of Diagnostic Medical Sonography, 22 2, 131-134Shekhar H.;Smith N.;Raymond J.;Holland C. 02-01-2018. Effect of Temperature on the Size Distribution, Shell Properties, and Stability of Definity<sup&g Ultrasound in Medicine and Biology, 44 2, 434-446Herbst S.M.;Klegerman M.E.;Kim H.;Qi J.;Shelat H.;Wassler M.;Moody M.R.;Yang C.M.;Ge X.;Zou Y.;Kopechek J.A.;Clubb F.J.;Kraemer D.C.;Huang S.;Holland C.K.;McPherson D.D.;Geng Y.J. 02-01-2010. Delivery of stem cells to porcine arterial wall with echogenic liposomes conjugated to antibodies ag Molecular Pharmaceutics, 7 1, 3-11 Holland C.K. 01-01-2022. Editorial Ultrasound in Medicine and Biology, 48 1, 1-2 Maxwell A.D.; Haworth K.J.; Holland C.K.; Hendley S.A.; Kreider W.; Bader K.B. 01-01-2022. Design and Characterization of an Ultrasound Transducer for Combined Histotripsy-Thrombolytic Therap IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 69 1, 156-165 Kee P.H.; Moody M.R.; Huang S.L.; Kim H.; Yin X.; Peng T.; Laing S.T.; Klegerman M.E.; Rahbar M.H.; Vela D.; Genstler C.; Haworth K.J.; Holland C.K.; McPherson D.D. 01-01-2020. Stabilizing Peri-Stent Restenosis Using a Novel Therapeutic Carrier JACC: Basic to Translational Science, 5 1, 1-11 Lafond M.; Shekhar H.; Panmanee W.; Collins S.D.; Palaniappan A.; McDaniel C.T.; Hassett D.J.; Holland C.K. 01-01-2020. Bactericidal activity of lipid-shelled nitric oxide-loaded microbubbles Frontiers in Pharmacology, 10 , Bader K.;Haworth K.;Maxwell A.;Holland C. 01-01-2018. Post Hoc Analysis of Passive Cavitation Imaging for Classification of Histotripsy-Induced Liquefacti IEEE Transactions on Medical Imaging, 37 1, 106-115Haworth K.;Bader K.;Rich K.;Holland C.;Mast T. 01-01-2017. Quantitative frequency-domain passive cavitation imaging IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 64 1, 177-191Mukherjee P.;Kandadai M.;Shaw G.;Holland C.;Papautsky I. 01-01-2015. Generation of drug loaded echogenic liposomes using microfluidic hydrodynamic focusing MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, , 466-468Ferrara K.;Griffin R.;Guha C.;Holland C.;Lafon C. 01-01-2013. TU?E?144?01: Advanced Novel Technologies & Therapeutic Strategies Medical Physics, 40 6, 451Holland C.;Shaw G.;Datta S. 01-01-2010. Ultrasound-enhanced thrombolysis Therapeutic Ultrasound: Mechanisms to Applications, , 239-260Fowlkes J.B.;Abramowicz J.S.;Church C.C.;Holland C.K.;Miller D.L.;O'Brien W.D.;Sanghvi N.T.;Stratmeyer M.E.;Zachary J.F.;Deng C.X.;Harris G.R.;Herman B.A.;Hynynen K.H.;Merritt C.R.B.;Thomenius K.E.;Bailey M.R.;Carson P.L.;Carstensen E.L.;Frizzell L.A.;Nyborg W.L.;Barnett S.B.;Duck F.A.;Edmonds P.D.;Ziskin M.C.;Abbott J.G.;Dalecki D.;Dunn F.;Greenleaf J.F.;Salvesen K.A.;Siddiqi T.A.;Averkiou M.A.;Brayman A.A.;Everbach E.C.;Wible J.H.;Wu J.;Simpson D.G. 01-01-2008. American Institute of Ultrasound in Medicine consensus report on potential bioeffects of diagnostic Journal of Ultrasound in Medicine, 27 4, 503-515Miller D.L.;Averkiou M.A.;Brayman A.A.;Everbach E.C.;Holland C.K.;Wible J.H.;Wu J. 01-01-2008. Bioeffects considerations for diagnostic ultrasound contrast agents Journal of Ultrasound in Medicine, 27 4, 611-632Holland C. 01-01-2007. Online review facilitates rapid publishing Ultrasound in Medicine and Biology, 33 1, 1-2Cheng J.;Shaw G.;Holland C. 01-01-2005. In vitro microscopic imaging of enhanced thrombolysis with 120-kHz ultrasound in a human clot model Acoustic Research Letters Online, 6 1, 25-29Holland C.;Everbach E. 01-01-2005. Guest editorial: Sono et Gravitas - The legacy of Robert Edmund Apfel Acoustic Research Letters Online, 6 3, Taylor C.;Holland C. 01-01-2003. Kenneth J. Taylor, MD, PhD, FACP, 1939-2003, pioneer of diagnostic ultrasound imaging. Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 22 6, 663-664Fowlkes J.;Holland C. 01-01-2000. Mechanical bioeffects from diagnostic ultrasound: AIUM consensus statements. American Institute of U Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 19 2, 69-72Fowlkes J.;Holland C.;Kremkau F. 01-01-2000. Mechanical bioeffects from diagnostic ultrasound: AIUM consensus statements Journal of Ultrasound in Medicine, 19 2, 68-168Deng C.;Xu Q.;Apfel R.;Holland C. 01-01-1996. Inertial cavitation produced by pulsed ultrasound in controlled host media Journal of the Acoustical Society of America, 100 2 I, 1199-1208Deng C.;Xu Q.;Apfel R.;Holland C. 01-01-1996. In vitro measurements of inertial cavitation thresholds in human blood Ultrasound in Medicine and Biology, 22 7, 939-948Brown J.M.;Hammers L.W.;Barton J.W.;Holland C.K.;Scoutt L.M.;Pellerito J.S.;Taylor K.J.W. 01-01-1995. Quantitative Doppler assessment of acute scrotal inflammation Radiology, 197 2, 427-431McCauley T.R.;Pena C.S.;Holland C.K.;Price T.B.;Gore J.C. 01-01-1995. Validation of volume flow measurements with cine phase?contrast MR imaging for peripheral arterial w Journal of Magnetic Resonance Imaging, 5 6, 663-668Reinhold C.;Hammers L.;Taylor C.;Quedens-Case C.;Holland C.;Taylor K. 01-01-1995. Characterization of focal hepatic lesions with duplex sonography: Findings in 198 patients American Journal of Roentgenology, 164 5, 1131-1135Dillon E.;Case C.;Ramos I.;Holland C.;Taylor K. 01-01-1993. Endovaginal pulsed and color doppler in first-trimester pregnancy Ultrasound in Medicine and Biology, 19 7, 517-525Dillon E.;Case C.;Ramos I.;Holland C.;Taylor K. 01-01-1993. Endovaginal US and Doppler findings after first-trimester abortion Radiology, 186 1, 87-91Holland C.;Taylor K. 01-01-1993. Blood flow quantitation: waveform analysis, volume measurement, tumor flow, and the role of color im Clinics in diagnostic ultrasound, 28 , 125-139Crum L.;Roy R.;Dinno M.;Church C.;Apfel R.;Holland C.;Madanshetty S. 01-01-1992. Acoustic cavitation produced by microsecond pulses of ultrasound: A discussion of some selected resu Journal of the Acoustical Society of America, 91 2, 1113-1119Holland C.;Roy R.;Apfel R.;Crum L. 01-01-1992. In Vitro Detection of Cavitation Induced by a Diagnostic Ultrasound System IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 39 1, 95-101Apfel R.;Holland C. 01-01-1991. Gauging the likelihood of cavitation from short-pulse, low-duty cycle diagnostic ultrasound Ultrasound in Medicine and Biology, 17 2, 179-185Holland C.;Apfel R. 01-01-1990. Thresholds for transient cavitation produced by pulsed ultrasound in a controlled nuclei environment Journal of the Acoustical Society of America, 88 5, 2059-2069Holland C. 01-01-1989. Thresholds of transient cavitation produced by pulsed ultrasound in a controlled nuclei environment Journal of the Acoustical Society of America, 86 2, 844Holland C.;Apfel R. 01-01-1989. An Improved Theory for the Prediction of Microcavitation Thresholds IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 36 2, 204-208Atchley A.;Frizzell L.;Apfel R.;Holland C.;Madanshetty S.;Roy R. 01-01-1988. Thresholds for cavitation produced in water by pulsed ultrasound Ultrasonics, 26 5, 280-285Bhatt, Seema R; Eckerle, Michelle D; Reed, Jennifer L; Robinson, Venita; Brown, Angela; Lippe, Joyce; Holland, Carolyn; Iyer, Srikant . Implementation of Targeted Point of Care HIV Testing in a Pediatric Emergency Department. Pediatric quality & safety, 5 1, e248
Research Interests Bioeffects of Diagnostic and Therapeutic Ultrasound Acoustic Cavitation New Diagnostic imaging Techniques for the Early Detection of Vascular Disease and Ischemic Injury to Brain
Peer Reviewed Publications Escudero, Daniel Suarez; Lafond, Maxime; Salido, Nuria G; Haworth, Kevin J; Hannah, Alexander S; Macke, Gregory P; Genstler, Curtis; Holland, Christy K 2023. Corrigendum to 'Cavitation emissions nucleated by Definity infused through an EkoSonic catheter in a flow phantom' [Ultrasound in Med & Biol. 47 (2021) 693-709]. Ultrasound in medicine & biology, 49 1, 410-414Kennedy, Sonya R; Lafond, Maxime; Haworth, Kevin J; Escudero, Daniel Suarez; Ionascu, Dan; Frierson, Brion; Huang, Shaoling; Klegerman, Melvin E; Peng, Tao; McPherson, David D; Genstler, Curtis; Holland, Christy K 2023. Initiating and imaging cavitation from infused echo contrast agents through the EkoSonic catheter. Scientific reports, 13 1, 6191Kleven, Robert T; Huang, Shenwen; Ford, Samantha M; Sakthivel, Karthikeyan; Thomas, Seth R; Zuccarello, Mario; Herr, Andrew B; Holland, Christy K 2023. Effect of Recombinant Tissue Plasminogen Activator and 120-kHz Ultrasound on Porcine Intracranial Thrombus Density. Ultrasound in medicine & biology, 49 2, 539-548Suarez Escudero, Daniel; Haworth, Kevin J; Genstler, Curtis; Holland, Christy K 2023. Quantifying the Effect of Acoustic Parameters on Temporal and Spatial Cavitation Activity: Gauging Cavitation Dose. Ultrasound in medicine & biology, 49 11, 2388-2397Hendley, Samuel A; Bhargava, Aarushi; Holland, Christy K; Wool, Geoffrey D; Ahmed, Osman; Paul, Jonathan D; Bader, Kenneth B 2022. (More than) doubling down: Effective fibrinolysis at a reduced rt-PA dose for catheter-directed thrombolysis combined with histotripsy. PloS one, 17 1, e0261567Klegerman, Melvin E; Moody, Melanie R; Huang, Shao-Ling; Peng, Tao; Laing, Susan T; Govindarajan, Vijay; Danila, Delia; Tahanan, Amirali; Rahbar, Mohammad H; Vela, Deborah; Genstler, Curtis; Haworth, Kevin J; Holland, Christy K; McPherson, David D; Kee, Patrick H 2022. Demonstration of ultrasound-mediated therapeutic delivery of fibrin-targeted pioglitazone-loaded echogenic liposomes into the arterial bed for attenuation of peri-stent restenosis. Journal of drug targeting, , 1-10Zemzemi, Chadi; Phillips, Matthew; Vela, Deborah C; Hilvert, Nicole A; Racadio, John M; Bader, Kenneth B; Haworth, Kevin J; Holland, Christy K 2022. Effect of Thrombin and Incubation Time on Porcine Whole Blood Clot Elasticity and Recombinant Tissue Plasminogen Activator Susceptibility. Ultrasound in medicine & biology, 48 8, 1567-1578Karunakaran, Chandra Priya; Burgess, Mark T; Rao, Marepalli B; Holland, Christy K; Mast, T Douglas 2021. Effect of Overpressure on Acoustic Emissions and Treated Tissue Histology in ex Vivo Bulk Ultrasound Ablation. Ultrasound in medicine & biology, 47 8, 2360-2376Kleven, Robert T; Karani, Kunal B; Hilvert, Nicole; Ford, Samantha M; Mercado-Shekhar, Karla P; Racadio, John M; Rao, Marepalli B; Abruzzo, Todd A; Holland, Christy K 2021. Accelerated sonothrombolysis with Definity in a xenographic porcine cerebral thromboembolism model. Scientific reports, 11 1, 3987Lafond, Maxime; Salido, Nuria G; Haworth, Kevin J; Hannah, Alexander S; Macke, Gregory P; Genstler, Curtis; Holland, Christy K 2021. Cavitation Emissions Nucleated by Definity Infused through an EkoSonic Catheter in a Flow Phantom. Ultrasound in medicine & biology, 47 3, 693-709Bollen, Viktor; Hendley, Samuel A; Paul, Jonathan D; Maxwell, Adam D; Haworth, Kevin J; Holland, Christy K; Bader, Kenneth B 2020. In Vitro Thrombolytic Efficacy of Single- and Five-Cycle Histotripsy Pulses and rt-PA. Ultrasound in medicine & biology, 46 2, 336-349Kee, Patrick H; Moody, Melanie R; Huang, Shao-Ling; Kim, Hyunggun; Yin, Xing; Peng, Tao; Laing, Susan T; Klegerman, Melvin E; Rahbar, Mohammad H; Vela, Deborah; Genstler, Curtis; Haworth, Kevin J; Holland, Christy K; McPherson, David D 2020. Stabilizing Peri-Stent Restenosis Using a Novel Therapeutic Carrier. JACC. Basic to translational science, 5 1, 1-11Kooiman, Klazina; Roovers, Silke; Langeveld, Simone A G; Kleven, Robert T; Dewitte, Heleen; O'Reilly, Meaghan A; Escoffre, Jean-Michel; Bouakaz, Ayache; Verweij, Martin D; Hynynen, Kullervo; Lentacker, Ine; Stride, Eleanor; Holland, Christy K 2020. Ultrasound-Responsive Cavitation Nuclei for Therapy and Drug Delivery. Ultrasound in medicine & biology, 46 6, 1296-1325Lattwein, Kirby R; Shekhar, Himanshu; Kouijzer, Joop J P; van Wamel, Willem J B; Holland, Christy K; Kooiman, Klazina 2020. Sonobactericide: An Emerging Treatment Strategy for Bacterial Infections. Ultrasound in medicine & biology, 46 2, 193-215Bader, Kenneth B; Gruber, Matthew J; Holland, Christy K 2019. Corrigendum to: "Shaken and Stirred: Mechanisms of Ultrasound-Enhanced Thrombolysis" in Ultrasound Med Biol 2015; 41(1): 187-196. Ultrasound in medicine & biology, 45 8, 2266Kleven, Robert T; Karani, Kunal B; Salido, Nuria G; Shekhar, Himanshu; Haworth, Kevin J; Mast, T Douglas; Tadesse, Dawit G; Holland, Christy K 2019. The effect of 220?kHz insonation scheme on rt-PA thrombolytic efficacy in vitro. Physics in medicine and biology, 64 16, 165015Lafond, Maxime; Shekhar, Himanshu; Panmanee, Warunya; Collins, Sydney D; Palaniappan, Arunkumar; McDaniel, Cameron T; Hassett, Daniel J; Holland, Christy K 2019. Bactericidal Activity of Lipid-Shelled Nitric Oxide-Loaded Microbubbles. Frontiers in pharmacology, 10 , 1540Mercado-Shekhar, Karla P; Kleven, Robert; Rivera, Hermes Aponte; Lewis, Ryden; Karani, Kunal B; Vos, Hendrik J; Abruzzo, Todd A; Haworth, Kevin J; Holland, Christy K 2019. Erratum to 'Effect of clot stiffness on recombinant tissue plasminogen activator lytic susceptibility in vitro' [Ultrasound Med Biol 44 (2018) 2710-2727]. Ultrasound in medicine & biology, 45 7, 1860Mercado-Shekhar, Karla P; Su, Haili; Kalaikadal, Deepak S; Lorenz, John N; Manglik, Raj M; Holland, Christy K; Redington, Andrew N; Haworth, Kevin J 2019. Acoustic droplet vaporization-mediated dissolved oxygen scavenging in blood-mimicking fluids, plasma, and blood. Ultrasonics sonochemistry, 56 , 114-124Shekhar, Himanshu; Kleven, Robert T; Peng, Tao; Palaniappan, Arunkumar; Karani, Kunal B; Huang, Shaoling; McPherson, David D; Holland, Christy K 2019. In vitro characterization of sonothrombolysis and echocontrast agents to treat ischemic stroke. Scientific reports, 9 1, 9902Shekhar, Himanshu; Palaniappan, Arunkumar; Peng, Tao; Lafond, Maxime; Moody, Melanie R; Haworth, Kevin J; Huang, Shaoling; McPherson, David D; Holland, Christy K 2019. Characterization and Imaging of Lipid-Shelled Microbubbles for Ultrasound-Triggered Release of Xenon. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 16 3, 878-890Lattwein, Kirby R; Shekhar, Himanshu; van Wamel, Willem J B; Gonzalez, Tammy; Herr, Andrew B; Holland, Christy K; Kooiman, Klazina 2018. An in vitro proof-of-principle study of sonobactericide. Scientific reports, 8 1, 3411Mercado-Shekhar, Karla P; Kleven, Robert T; Aponte Rivera, Hermes; Lewis, Ryden; Karani, Kunal B; Vos, Hendrik J; Abruzzo, Todd A; Haworth, Kevin J; Holland, Christy K 2018. Effect of Clot Stiffness on Recombinant Tissue Plasminogen Activator Lytic Susceptibility in Vitro. Ultrasound in medicine & biology, 44 12, 2710-2727Rich, Kyle T; Holland, Christy K; Rao, Marepalli B; Mast, T Douglas 2018. Characterization of cavitation-radiated acoustic power using diffraction correction. The Journal of the Acoustical Society of America, 144 6, 3563Shekhar, Himanshu; Smith, Nathaniel J; Raymond, Jason L; Holland, Christy K 2018. Effect of Temperature on the Size Distribution, Shell Properties, and Stability of Definity®. Ultrasound in medicine & biology, 44 2, 434-446Beigel, John H; Tebas, Pablo; Elie-Turenne, Marie-Carmelle; Bajwa, Ednan; Bell, Todd E; Cairns, Charles B; Shoham, Shmuel; Deville, Jaime G; Feucht, Eric; Feinberg, Judith; Luke, Thomas; Raviprakash, Kanakatte; Danko, Janine; O'Neil, Dorothy; Metcalf, Julia A; King, Karen; Burgess, Timothy H; Aga, Evgenia; Lane, H Clifford; Hughes, Michael D; Davey, Richard T 2017. Immune plasma for the treatment of severe influenza: an open-label, multicentre, phase 2 randomised study. The Lancet. Respiratory medicine, 5 6, 500-511Haworth, Kevin J; Goldstein, Bryan H; Mercado-Shekhar, Karla P; Srivastava, Rohan; Arunkumar, P; Su, Haili; Privitera, Ellena M; Holland, Christy K; Redington, Andrew N 2017. Dissolved Oxygen Scavenging by Acoustic Droplet Vaporization using Intravascular Ultrasound. IEEE International Ultrasonics Symposium : [proceedings]. IEEE International Ultrasonics Symposium, 2017 , Huang, Shenwen; Shekhar, Himanshu; Holland, Christy K 2017. Comparative lytic efficacy of rt-PA and ultrasound in porcine versus human clots. PloS one, 12 5, e0177786Shekhar, Himanshu; Bader, Kenneth B; Huang, Shenwen; Peng, Tao; Huang, Shaoling; McPherson, David D; Holland, Christy K 2017. In vitro thrombolytic efficacy of echogenic liposomes loaded with tissue plasminogen activator and octafluoropropane gas. Physics in medicine and biology, 62 2, 517-538Bader, Kenneth B; Bouchoux, Guillaume; Holland, Christy K 2016. Sonothrombolysis. Advances in experimental medicine and biology, 880 , 339-62Bader, Kenneth B; Crowe, Michael J; Raymond, Jason L; Holland, Christy K 2016. Effect of Frequency-Dependent Attenuation on Predicted Histotripsy Waveforms in Tissue-Mimicking Phantoms. Ultrasound in medicine & biology, 42 7, 1701-5Bader, Kenneth B; Haworth, Kevin J; Shekhar, Himanshu; Maxwell, Adam D; Peng, Tao; McPherson, David D; Holland, Christy K 2016. Efficacy of histotripsy combined with rt-PA in vitro. Physics in medicine and biology, 61 14, 5253-74Bader, Kenneth B; Holland, Christy K 2016. Predicting the growth of nanoscale nuclei by histotripsy pulses. Physics in medicine and biology, 61 7, 2947-66Haworth, Kevin J; Raymond, Jason L; Radhakrishnan, Kirthi; Moody, Melanie R; Huang, Shao-Ling; Peng, Tao; Shekhar, Himanshu; Klegerman, Melvin E; Kim, Hyunggun; McPherson, David D; Holland, Christy K 2016. Erratum to: "Trans-stent B-mode Ultrasound and Passive Cavitation Imaging" in Ultrasound Med Biol 2016;42(2):518-527. Ultrasound in medicine & biology, 42 5, 1244Haworth, Kevin J; Raymond, Jason L; Radhakrishnan, Kirthi; Moody, Melanie R; Huang, Shao-Ling; Peng, Tao; Shekhar, Himanshu; Klegerman, Melvin E; Kim, Hyunggun; McPherson, David D; Holland, Christy K 2016. Trans-Stent B-Mode Ultrasound and Passive Cavitation Imaging. Ultrasound in medicine & biology, 42 2, 518-27Kandadai, Madhuvanthi A; Mukherjee, Prithviraj; Shekhar, Himanshu; Shaw, George J; Papautsky, Ian; Holland, Christy K 2016. Microfluidic manufacture of rt-PA -loaded echogenic liposomes. Biomedical microdevices, 18 3, 48Klegerman, Melvin E; Naji, Ali K; Haworth, Kevin J; Zou, Yuejiao; Golunski, Eva; Peng, Tao; Britton, George L; Huang, Shao-Ling; Holland, Christy K; McPherson, David D 2016. Ultrasound-enhanced bevacizumab release from echogenic liposomes for inhibition of atheroma progression. Journal of liposome research, 26 1, 47-56Radhakrishnan, Kirthi; Holland, Christy K; Haworth, Kevin J 2016. Scavenging dissolved oxygen via acoustic droplet vaporization. Ultrasonics sonochemistry, 31 , 394-403Raymond, Jason L; Luan, Ying; Peng, Tao; Huang, Shao-Ling; McPherson, David D; Versluis, Michel; de Jong, Nico; Holland, Christy K 2016. Loss of gas from echogenic liposomes exposed to pulsed ultrasound. Physics in medicine and biology, 61 23, 8321-8339Sutton, J T; Haworth, K J; Shanmukhappa, S K; Moody, M R; Klegerman, M E; Griffin, J K; Patton, D M; McPherson, D D; Holland, C K 2016. Delivery of bevacizumab to atheromatous porcine carotid tissue using echogenic liposomes. Drug delivery, 23 9, 3594-3605Bader, Kenneth B; Bouchoux, Guillaume; Peng, Tao; Klegerman, Melvin E; McPherson, David D; Holland, Christy K 2015. Thrombolytic efficacy and enzymatic activity of rt-PA-loaded echogenic liposomes. Journal of thrombosis and thrombolysis, , Bader, Kenneth B; Gruber, Matthew J; Holland, Christy K 2015. Shaken and stirred: mechanisms of ultrasound-enhanced thrombolysis. Ultrasound in medicine & biology, 41 1, 187-96Haworth, Kevin J; Salgaonkar, Vasant A; Corregan, Nicholas M; Holland, Christy K; Mast, T Douglas 2015. Using Passive Cavitation Images to Classify High-Intensity Focused Ultrasound Lesions. Ultrasound in medicine & biology, 41 9, 2420-34Holland, C 2015. WE-D-210-03: Microbubble Pumps: Â Ultrasound Theragnostic Agents. Medical physics, 42 6, 3672Kandadai, Madhuvanthi A; Meunier, Jason M; Hart, Kimberley; Holland, Christy K; Shaw, George J 2015. Plasmin-loaded echogenic liposomes for ultrasound-mediated thrombolysis. Translational stroke research, 6 1, 78-87Radhakrishnan, Kirthi; Haworth, Kevin J; Peng, Tao; McPherson, David D; Holland, Christy K 2015. Loss of echogenicity and onset of cavitation from echogenic liposomes: pulse repetition frequency independence. Ultrasound in medicine & biology, 41 1, 208-21Raymond, Jason L; Luan, Ying; van Rooij, Tom; Kooiman, Klazina; Huang, Shao-Ling; McPherson, David D; Versluis, Michel; de Jong, Nico; Holland, Christy K 2015. Impulse response method for characterization of echogenic liposomes. The Journal of the Acoustical Society of America, 137 4, 1693-703Bouchoux, Guillaume; Shivashankar, Ravishankar; Abruzzo, Todd A; Holland, Christy K 2014. In silico study of low-frequency transcranial ultrasound fields in acute ischemic stroke patients. Ultrasound in medicine & biology, 40 6, 1154-66Gruber, Matthew J; Bader, Kenneth B; Holland, Christy K 2014. Cavitation thresholds of contrast agents in an in vitro human clot model exposed to 120-kHz ultrasound. The Journal of the Acoustical Society of America, 135 2, 646-53Haworth, Kevin J; Weidner, Christopher R; Abruzzo, Todd A; Shearn, Jason T; Holland, Christy K 2014. Mechanical properties and fibrin characteristics of endovascular coil-clot complexes: relevance to endovascular cerebral aneurysm repair paradigms. Journal of neurointerventional surgery, , Kim, Hyunggun; Britton, George L; Peng, Tao; Holland, Christy K; McPherson, David D; Huang, Shao-Ling 2014. Nitric oxide-loaded echogenic liposomes for treatment of vasospasm following subarachnoid hemorrhage. International journal of nanomedicine, 9 , 155-65Raymond, Jason L; Haworth, Kevin J; Bader, Kenneth B; Radhakrishnan, Kirthi; Griffin, Joseph K; Huang, Shao-Ling; McPherson, David D; Holland, Christy K 2014. Broadband attenuation measurements of phospholipid-shelled ultrasound contrast agents. Ultrasound in medicine & biology, 40 2, 410-21Sutton, J T; Raymond, J L; Verleye, M C; Pyne-Geithman, G J; Holland, C K 2014. Pulsed ultrasound enhances the delivery of nitric oxide from bubble liposomes to ex vivo porcine carotid tissue. International journal of nanomedicine, 9 , 4671-83Bader, K. B.; Holland, C. K. 2013. Gauging the likelihood of stable cavitation from ultrasound contrast agents Phys Med Biol, 58 1 , 127-44Bader, Kenneth B; Holland, Christy K 2013. Gauging the likelihood of stable cavitation from ultrasound contrast agents. Physics in medicine and biology, 58 1, 127-44Haworth, K. J.; Salgaonkar, V. A.; Corregan, N. M.; Holland, C. K.; Mast, T. D. 2013. Spatial specificity and sensitivity of passive cavitation imaging for monitoring high-intensity focused ultrasound thermal ablation in ex vivo bovine liver J Acoust Soc Am, 133 5 , 3263Kopechek, J. A.; Haworth, K. J.; Radhakrishnan, K.; Huang, S. L.; Klegerman, M. E.; McPherson, D. D.; Holland, C. K. 2013. The impact of bubbles on measurement of drug release from echogenic liposomes Ultrason Sonochem, 20 4 , 1121-30Kopechek, Jonathan A; Haworth, Kevin J; Radhakrishnan, Kirthi; Huang, Shao-Ling; Klegerman, Melvin E; McPherson, David D; Holland, Christy K 2013. The impact of bubbles on measurement of drug release from echogenic liposomes. Ultrasonics sonochemistry, 20 4, 1121-30Radhakrishnan, Kirthi; Bader, Kenneth B; Haworth, Kevin J; Kopechek, Jonathan A; Raymond, Jason L; Huang, Shao-Ling; McPherson, David D; Holland, Christy K 2013. Relationship between cavitation and loss of echogenicity from ultrasound contrast agents. Physics in medicine and biology, 58 18, 6541-63Sutton, J. T.; Ivancevich, N. M.; Perrin, S. R., Jr.; Vela, D. C.; Holland, C. K. 2013. Clot retraction affects the extent of ultrasound-enhanced thrombolysis in an ex vivo porcine thrombosis model Ultrasound Med Biol, 39 5 , 813-24Sutton, J. T.; Haworth, K. J.; Pyne-Geithman, G.; Holland, C. K. 2013. Ultrasound-mediated drug delivery for cardiovascular disease Expert Opin Drug Deliv, 10 5 , 573-92Sutton, Jonathan T; Haworth, Kevin J; Pyne-Geithman, Gail; Holland, Christy K 2013. Ultrasound-mediated drug delivery for cardiovascular disease. Expert opinion on drug delivery, 10 5, 573-92Sutton, Jonathan T; Ivancevich, Nikolas M; Perrin, Stephen R; Vela, Deborah C; Holland, Christy K 2013. Clot retraction affects the extent of ultrasound-enhanced thrombolysis in an ex vivo porcine thrombosis model. Ultrasound in medicine & biology, 39 5, 813-24Bouchoux, G.; Bader, K. B.; Korfhagen, J. J.; Raymond, J. L.; Shivashankar, R.; Abruzzo, T. A.; Holland, C. K. 2012. Experimental validation of a finite-difference model for the prediction of transcranial ultrasound fields based on CT images Phys Med Biol, 57 23 , 8005-22Bouchoux, Guillaume; Bader, Kenneth B; Korfhagen, Joseph J; Raymond, Jason L; Shivashankar, Ravishankar; Abruzzo, Todd A; Holland, Christy K 2012. Experimental validation of a finite-difference model for the prediction of transcranial ultrasound fields based on CT images. Physics in medicine and biology, 57 23, 8005-22Haworth, K. J.; Mast, T. D.; Radhakrishnan, K.; Burgess, M. T.; Kopechek, J. A.; Huang, S. L.; McPherson, D. D.; Holland, C. K. 2012. Passive imaging with pulsed ultrasound insonations J Acoust Soc Am, 132 1 , 544-53Haworth, Kevin J; Mast, T Douglas; Radhakrishnan, Kirthi; Burgess, Mark T; Kopechek, Jonathan A; Huang, Shao-Ling; McPherson, David D; Holland, Christy K 2012. Passive imaging with pulsed ultrasound insonations. The Journal of the Acoustical Society of America, 132 1, 544-53Huppert, Jill S; Reed, Jennifer L; Munafo, Jennifer Knopf; Ekstrand, Rachel; Gillespie, Gordon; Holland, Carolyn; Britto, Maria T 2012. Improving notification of sexually transmitted infections: a quality improvement project and planned experiment. Pediatrics, 130 2, e415-22Laing, S. T.; Moody, M. R.; Kim, H.; Smulevitz, B.; Huang, S. L.; Holland, C. K.; McPherson, D. D.; Klegerman, M. E. 2012. Thrombolytic efficacy of tissue plasminogen activator-loaded echogenic liposomes in a rabbit thrombus model Thromb Res, 130 4 , 629-35Radhakrishnan, K.; Haworth, K. J.; Huang, S. L.; Klegerman, M. E.; McPherson, D. D.; Holland, C. K. 2012. Stability of echogenic liposomes as a blood pool ultrasound contrast agent in a physiologic flow phantom Ultrasound Med Biol, 38 11 , 1970-81Radhakrishnan, Kirthi; Haworth, Kevin J; Huang, Shao-Ling; Klegerman, Melvin E; McPherson, David D; Holland, Christy K 2012. Stability of echogenic liposomes as a blood pool ultrasound contrast agent in a physiologic flow phantom. Ultrasound in medicine & biology, 38 11, 1970-81Hitchcock, K. E.; Ivancevich, N. M.; Haworth, K. J.; Caudell Stamper, D. N.; Vela, D. C.; Sutton, J. T.; Pyne-Geithman, G. J.; Holland, C. K. 2011. Ultrasound-enhanced rt-PA thrombolysis in an ex vivo porcine carotid artery model Ultrasound Med Biol, 37 8 , 1240-51Hitchcock, Kathryn E; Ivancevich, Nikolas M; Haworth, Kevin J; Caudell Stamper, Danielle N; Vela, Deborah C; Sutton, Jonathan T; Pyne-Geithman, Gail J; Holland, Christy K 2011. Ultrasound-enhanced rt-PA thrombolysis in an ex vivo porcine carotid artery model. Ultrasound in medicine & biology, 37 8, 1240-51Kopechek, J. A.; Haworth, K. J.; Raymond, J. L.; Douglas Mast, T.; Perrin, S. R.; Klegerman, M. E.; Huang, S.; Porter, T. M.; McPherson, D. D.; Holland, C. K. 2011. Acoustic characterization of echogenic liposomes: frequency-dependent attenuation and backscatter J Acoust Soc Am, 130 5 , 3472-81Kopechek, Jonathan A; Haworth, Kevin J; Raymond, Jason L; Douglas Mast, T; Perrin, Stephen R; Klegerman, Melvin E; Huang, Shaoling; Porter, Tyrone M; McPherson, David D; Holland, Christy K 2011. Acoustic characterization of echogenic liposomes: frequency-dependent attenuation and backscatter. The Journal of the Acoustical Society of America, 130 5, 3472-81Laing, S. T.; Moody, M.; Smulevitz, B.; Kim, H.; Kee, P.; Huang, S.; Holland, C. K.; McPherson, D. D. 2011. Ultrasound-enhanced thrombolytic effect of tissue plasminogen activator-loaded echogenic liposomes in an in vivo rabbit aorta thrombus model--brief report Arterioscler Thromb Vasc Biol, 31 6 , 1357-9Meunier, J. M.; Holland, C. K.; Porter, T. M.; Lindsell, C. J.; Shaw, G. J. 2011. Combination treatment with rt-PA is more effective than rt-PA alone in an in vitro human clot model Curr Neurovasc Res, 8 4 , 305-12Meunier, Jason M; Holland, Christy K; Porter, Tyrone M; Lindsell, Christopher J; Shaw, George J 2011. Combination treatment with rt-PA is more effective than rt-PA alone in an in vitro human clot model. Current neurovascular research, 8 4, 305-12Britton, G. L.; Kim, H.; Kee, P. H.; Aronowski, J.; Holland, C. K.; McPherson, D. D.; Huang, S. L. 2010. In vivo therapeutic gas delivery for neuroprotection with echogenic liposomes Circulation, 122 16 , 1578-87Herbst, S. M.; Klegerman, M. E.; Kim, H.; Qi, J.; Shelat, H.; Wassler, M.; Moody, M. R.; Yang, C. M.; Ge, X.; Zou, Y.; Kopechek, J. A.; Clubb, F. J.; Kraemer, D. C.; Huang, S.; Holland, C. K.; McPherson, D. D.; Geng, Y. J. 2010. Delivery of stem cells to porcine arterial wall with echogenic liposomes conjugated to antibodies against CD34 and intercellular adhesion molecule-1 Mol Pharm, 7 1 , 3-11Hitchcock, K. E.; Caudell, D. N.; Sutton, J. T.; Klegerman, M. E.; Vela, D.; Pyne-Geithman, G. J.; Abruzzo, T.; Cyr, P. E.; Geng, Y. J.; McPherson, D. D.; Holland, C. K. 2010. Ultrasound-enhanced delivery of targeted echogenic liposomes in a novel ex vivo mouse aorta model J Control Release, 144 3 , 288-95Hitchcock, K. E.; Holland, C. K. 2010. Ultrasound-assisted thrombolysis for stroke therapy: better thrombus break-up with bubbles Stroke, 41 10 Suppl , S50-3Hitchcock, Kathryn E; Caudell, Danielle N; Sutton, Jonathan T; Klegerman, Melvin E; Vela, Deborah; Pyne-Geithman, Gail J; Abruzzo, Todd; Cyr, Peppar E P; Geng, Yong-Jian; McPherson, David D; Holland, Christy K 2010. Ultrasound-enhanced delivery of targeted echogenic liposomes in a novel ex vivo mouse aorta model. Journal of controlled release : official journal of the Controlled Release Society, 144 3, 288-95Hitchcock, Kathryn E; Holland, Christy K 2010. Ultrasound-assisted thrombolysis for stroke therapy: better thrombus break-up with bubbles. Stroke; a journal of cerebral circulation, 41 10 Suppl, S50-3Klegerman, M. E.; Wassler, M.; Huang, S. L.; Zou, Y.; Kim, H.; Shelat, H. S.; Holland, C. K.; Geng, Y. J.; McPherson, D. D. 2010. Liposomal modular complexes for simultaneous targeted delivery of bioactive gases and therapeutics J Control Release, 142 3 , 326-31Kopechek, J. A.; Kim, H.; McPherson, D. D.; Holland, C. K. 2010. Calibration of the 1-MHz Sonitron ultrasound system Ultrasound Med Biol, 36 10 , 1762-6Kopechek, Jonathan A; Kim, Hyunggun; McPherson, David D; Holland, Christy K 2010. Calibration of the 1-MHz Sonitron ultrasound system. Ultrasound in medicine & biology, 36 10, 1762-6Laing, S. T.; Kim, H.; Kopechek, J. A.; Parikh, D.; Huang, S.; Klegerman, M. E.; Holland, C. K.; McPherson, D. D. 2010. Ultrasound-mediated delivery of echogenic immunoliposomes to porcine vascular smooth muscle cells in vivo J Liposome Res, 20 2 , 160-7Shaw, G. J.; Meunier, J. M.; Lindsell, C. J.; Pancioli, A. M.; Holland, C. K. 2010. Making the right choice: optimizing rt-PA and eptifibatide lysis, an in vitro study Thromb Res, 126 4 , e305-11Shaw, George J; Meunier, Jason M; Lindsell, Christopher J; Pancioli, Arthur M; Holland, Christy K 2010. Making the right choice: optimizing rt-PA and eptifibatide lysis, an in vitro study. Thrombosis research, 126 4, e305-11Smith, D. A.; Vaidya, S. S.; Kopechek, J. A.; Huang, S. L.; Klegerman, M. E.; McPherson, D. D.; Holland, C. K. 2010. Ultrasound-triggered release of recombinant tissue-type plasminogen activator from echogenic liposomes Ultrasound Med Biol, 36 1 , 145-57Smith, Denise A B; Vaidya, Sampada S; Kopechek, Jonathan A; Huang, Shao-Ling; Klegerman, Melvin E; McPherson, David D; Holland, Christy K 2010. Ultrasound-triggered release of recombinant tissue-type plasminogen activator from echogenic liposomes. Ultrasound in medicine & biology, 36 1, 145-57Holland, C. K.; McPherson, D. D. 2009. Echogenic Lipsomes for Targeted Drug Delivery Proc IEEE Int Symp Biomed Imaging, 2009 3 , 755-758Holland, Christy K; McPherson, David D 2009. ECHOGENIC LIPSOMES FOR TARGETED DRUG DELIVERY. Proceedings / IEEE International Symposium on Biomedical Imaging: from nano to macro. IEEE International Symposium on Biomedical Imaging, 2009 , 755-758Meunier, J. M.; Holland, C. K.; Pancioli, A. M.; Lindsell, C. J.; Shaw, G. J. 2009. Effect of low frequency ultrasound on combined rt-PA and eptifibatide thrombolysis in human clots Thromb Res, 123 3 , 528-36Meunier, Jason M; Holland, Christy K; Pancioli, Arthur M; Lindsell, Christopher J; Shaw, George J 2009. Effect of low frequency ultrasound on combined rt-PA and eptifibatide thrombolysis in human clots. Thrombosis research, 123 3, 528-36Salgaonkar, V. A.; Datta, S.; Holland, C. K.; Mast, T. D. 2009. Passive cavitation imaging with ultrasound arrays J Acoust Soc Am, 126 6 , 3071-83Salgaonkar, Vasant A; Datta, Saurabh; Holland, Christy K; Mast, T Douglas 2009. Passive cavitation imaging with ultrasound arrays. The Journal of the Acoustical Society of America, 126 6, 3071-83Shaw, G. J.; Meunier, J. M.; Huang, S. L.; Lindsell, C. J.; McPherson, D. D.; Holland, C. K. 2009. Ultrasound-enhanced thrombolysis with tPA-loaded echogenic liposomes Thromb Res, 124 3 , 306-10Shaw, George J; Meunier, Jason M; Huang, Shao-Ling; Lindsell, Christopher J; McPherson, David D; Holland, Christy K 2009. Ultrasound-enhanced thrombolysis with tPA-loaded echogenic liposomes. Thrombosis research, 124 3, 306-10Ammi, A. Y.; Mast, T. D.; Huang, I. H.; Abruzzo, T. A.; Coussios, C. C.; Shaw, G. J.; Holland, C. K. 2008. Characterization of ultrasound propagation through ex-vivo human temporal bone Ultrasound Med Biol, 34 10 , 1578-89Ammi, Azzdine Y; Mast, T Douglas; Huang, I-Hua; Abruzzo, Todd A; Coussios, Constantin-C; Shaw, George J; Holland, Christy K 2008. Characterization of ultrasound propagation through ex-vivo human temporal bone. Ultrasound in medicine & biology, 34 10, 1578-89Datta, S.; Coussios, C. C.; Ammi, A. Y.; Mast, T. D.; de Courten-Myers, G. M.; Holland, C. K. 2008. Ultrasound-enhanced thrombolysis using Definity as a cavitation nucleation agent Ultrasound Med Biol, 34 9 , 1421-33Datta, Saurabh; Coussios, Constantin-C; Ammi, Azzdine Y; Mast, T Douglas; de Courten-Myers, Gabrielle M; Holland, Christy K 2008. Ultrasound-enhanced thrombolysis using Definity as a cavitation nucleation agent. Ultrasound in medicine & biology, 34 9, 1421-33Holland, C. K.; Vaidya, S. S.; Datta, S.; Coussios, C. C.; Shaw, G. J. 2008. Ultrasound-enhanced tissue plasminogen activator thrombolysis in an in vitro porcine clot model Thromb Res, 121 5 , 663-73Holland, Christy K; Vaidya, Sampada S; Datta, Saurabh; Coussios, Constantin-C; Shaw, George J 2008. Ultrasound-enhanced tissue plasminogen activator thrombolysis in an in vitro porcine clot model. Thrombosis research, 121 5, 663-73Kee, P. H.; Abruzzo, T. A.; Smith, D. A.; Kopechek, J. A.; Wang, B.; Huang, S. L.; MacDonald, R. C.; Holland, C. K.; McPherson, D. D. 2008. Synthesis, acoustic stability, and pharmacologic activities of papaverine-loaded echogenic liposomes for ultrasound controlled drug delivery J Liposome Res, 18 4 , 263-77Kopechek, J. A.; Abruzzo, T. M.; Wang, B.; Chrzanowski, S. M.; Smith, D. A.; Kee, P. H.; Huang, S.; Collier, J. H.; McPherson, D. D.; Holland, C. K. 2008. Ultrasound-mediated release of hydrophilic and lipophilic agents from echogenic liposomes J Ultrasound Med, 27 11 , 1597-606Kopechek, Jonathan A; Abruzzo, Todd M; Wang, Boyu; Chrzanowski, Stephen M; Smith, Denise A B; Kee, Patrick H; Huang, Shaoling; Collier, Joel H; McPherson, David D; Holland, Christy K 2008. Ultrasound-mediated release of hydrophilic and lipophilic agents from echogenic liposomes. Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 27 11, 1597-606Mast, T Douglas; Salgaonkar, Vasant A; Karunakaran, Chandrapriya; Besse, John A; Datta, Saurabh; Holland, Christy K 2008. Acoustic emissions during 3.1 MHz ultrasound bulk ablation in vitro. Ultrasound in medicine & biology, 34 9, 1434-48Mast, T. D.; Salgaonkar, V. A.; Karunakaran, C.; Besse, J. A.; Datta, S.; Holland, C. K. 2008. Acoustic emissions during 3.1 MHz ultrasound bulk ablation in vitro Ultrasound Med Biol, 34 9 , 1434-48Miller, D. L.; Averkiou, M. A.; Brayman, A. A.; Everbach, E. C.; Holland, C. K.; Wible, J. H., Jr.; Wu, J. 2008. Bioeffects considerations for diagnostic ultrasound contrast agents J Ultrasound Med, 27 4 , 611-32; quiz 633-6Shaw, G. J.; Meunier, J. M.; Lindsell, C. J.; Holland, C. K. 2008. Tissue plasminogen activator concentration dependence of 120 kHz ultrasound-enhanced thrombolysis Ultrasound Med Biol, 34 11 , 1783-92Shaw, George J; Meunier, Jason M; Lindsell, Christopher J; Holland, Christy K 2008. Tissue plasminogen activator concentration dependence of 120 kHz ultrasound-enhanced thrombolysis. Ultrasound in medicine & biology, 34 11, 1783-92Wang, Y.; Krishnamoorthy, M.; Banerjee, R.; Zhang, J.; Rudich, S.; Holland, C.; Arend, L.; Roy-Chaudhury, P. 2008. Venous stenosis in a pig arteriovenous fistula model--anatomy, mechanisms and cellular phenotypes Nephrol Dial Transplant, 23 2 , 525-33Wang, Yang; Krishnamoorthy, Mahesh; Banerjee, Rupak; Zhang, Jianhua; Rudich, Steven; Holland, Christy; Arend, Lois; Roy-Chaudhury, Prabir 2008. Venous stenosis in a pig arteriovenous fistula model--anatomy, mechanisms and cellular phenotypes. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 23 2, 525-33Zhou, X.; Espy-Wilson, C. Y.; Boyce, S.; Tiede, M.; Holland, C.; Choe, A. 2008. A magnetic resonance imaging-based articulatory and acoustic study of "retroflex" and "bunched" American English /r J Acoust Soc Am, 123 6 , 4466-81Meunier, J. M.; Holland, C. K.; Lindsell, C. J.; Shaw, G. J. 2007. Duty cycle dependence of ultrasound enhanced thrombolysis in a human clot model Ultrasound Med Biol, 33 4 , 576-83Meunier, Jason M; Holland, Christy K; Lindsell, Christopher J; Shaw, George J 2007. Duty cycle dependence of ultrasound enhanced thrombolysis in a human clot model. Ultrasound in medicine & biology, 33 4, 576-83Nahirnyak, V.; Mast, T. D.; Holland, C. K. 2007. Ultrasound-induced thermal elevation in clotted blood and cranial bone Ultrasound Med Biol, 33 8 , 1285-95Nahirnyak, Volodymyr; Mast, T Douglas; Holland, Christy K 2007. Ultrasound-induced thermal elevation in clotted blood and cranial bone. Ultrasound in medicine & biology, 33 8, 1285-95Shaw, G. J.; Dhamija, A.; Bavani, N.; Wagner, K. R.; Holland, C. K. 2007. Arrhenius temperature dependence of in vitro tissue plasminogen activator thrombolysis Phys Med Biol, 52 11 , 2953-67Shaw, George J; Dhamija, Ashima; Bavani, Nazli; Wagner, Kenneth R; Holland, Christy K 2007. Arrhenius temperature dependence of in vitro tissue plasminogen activator thrombolysis. Physics in medicine and biology, 52 11, 2953-67Smith, D. A.; Porter, T. M.; Martinez, J.; Huang, S.; MacDonald, R. C.; McPherson, D. D.; Holland, C. K. 2007. Destruction thresholds of echogenic liposomes with clinical diagnostic ultrasound Ultrasound Med Biol, 33 5 , 797-809Smith, Denise A B; Porter, Tyrone M; Martinez, Janet; Huang, Shaoling; MacDonald, Robert C; McPherson, David D; Holland, Christy K 2007. Destruction thresholds of echogenic liposomes with clinical diagnostic ultrasound. Ultrasound in medicine & biology, 33 5, 797-809Tiukinhoy-Laing, S. D.; Huang, S.; Klegerman, M.; Holland, C. K.; McPherson, D. D. 2007. Ultrasound-facilitated thrombolysis using tissue-plasminogen activator-loaded echogenic liposomes Thromb Res, 119 6 , 777-84Datta, S.; Coussios, C. C.; McAdory, L. E.; Tan, J.; Porter, T.; De Courten-Myers, G.; Holland, C. K. 2006. Correlation of cavitation with ultrasound enhancement of thrombolysis Ultrasound Med Biol, 32 8 , 1257-67Datta, Saurabh; Coussios, Constantin-C; McAdory, Louis E; Tan, Jun; Porter, Tyrone; De Courten-Myers, Gabrielle; Holland, Christy K 2006. Correlation of cavitation with ultrasound enhancement of thrombolysis. Ultrasound in medicine & biology, 32 8, 1257-67More, S. R.; Lim, T. C.; Li, M.; Holland, C. K.; Boyce, S. E.; Lee, J. H. 2006. Acoustic noise characteristics of a 4 Telsa MRI scanner J Magn Reson Imaging, 23 3 , 388-97More, Shashikant R; Lim, Teik C; Li, Mingfeng; Holland, Christy K; Boyce, Suzanne E; Lee, Jing-Huei 2006. Acoustic noise characteristics of a 4 Telsa MRI scanner. Journal of magnetic resonance imaging : JMRI, 23 3, 388-97Nahirnyak, V. M.; Yoon, S. W.; Holland, C. K. 2006. Acousto-mechanical and thermal properties of clotted blood J Acoust Soc Am, 119 6 , 3766-72Nahirnyak, Volodymyr M; Yoon, Suk Wang; Holland, Christy K 2006. Acousto-mechanical and thermal properties of clotted blood. The Journal of the Acoustical Society of America, 119 6, 3766-72Porter, T. M.; Smith, D. A.; Holland, C. K. 2006. Acoustic techniques for assessing the Optison destruction threshold J Ultrasound Med, 25 12 , 1519-29Porter, Tyrone M; Smith, Denise A B; Holland, Christy K 2006. Acoustic techniques for assessing the Optison destruction threshold. Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 25 12, 1519-29Wright, S. W.; Lindsell, C. J.; Hinckley, W. R.; Williams, A.; Holland, C.; Lewis, C. H.; Heimburger, G. 2006. High fidelity medical simulation in the difficult environment of a helicopter: feasibility, self-efficacy and cost BMC Med Educ, 6 4 , 49Wright, Stewart W; Lindsell, Christopher J; Hinckley, William R; Williams, Annette; Holland, Carolyn; Lewis, Christopher H; Heimburger, Gail 2006. High fidelity medical simulation in the difficult environment of a helicopter: feasibility, self-efficacy and cost. BMC medical education, 6 , 49Cheng, J. Y.; Shaw, G. J.; Holland, C. K. 2005. In vitro microscopic imaging of enhanced thrombolysis with 120-kHz ultrasound in a human clot model Acoust Res Lett Online, 6 1 , 25-29Cheng, Jason Y; Shaw, George J; Holland, Christy K 2005. In vitro microscopic imaging of enhanced thrombolysis with 120-kHz ultrasound in a human clot model. Acoustics research letters online : ARLO, 6 1, 25-29Coussios, C. C.; Holland, C. K.; Jakubowska, L.; Huang, S. L.; MacDonald, R. C.; Nagaraj, A.; McPherson, D. D. 2004. In vitro characterization of liposomes and Optison by acoustic scattering at 3.5 MHz Ultrasound Med Biol, 30 2 , 181-90Coussios, Constantin-C; Holland, Christy K; Jakubowska, Ludwika; Huang, Shao-Ling; MacDonald, Robert C; Nagaraj, Ashwin; McPherson, David D 2004. In vitro characterization of liposomes and Optison by acoustic scattering at 3.5 MHz. Ultrasound in medicine & biology, 30 2, 181-90McPherson, D. D.; Holland, C. K. 2003. Seizing the science of ultrasound: beyond imaging and into physiology and therapeutics J Am Coll Cardiol, 41 9 , 1628-30Taylor, C. R.; Holland, C. K. 2003. Kenneth J. Taylor, MD, PhD, FACP, 1939-2003, pioneer of diagnostic ultrasound imaging J Ultrasound Med, 22 6 , 663-4Fowlkes, J. B.; Holland, C. K. 2000. Mechanical bioeffects from diagnostic ultrasound: AIUM consensus statements. American Institute of Ultrasound in Medicine J Ultrasound Med, 19 2 , 69-72Ouanounou, S.; Tomsick, T. A.; Heitsman, C.; Holland, C. K. 1999. Cavernous sinus and inferior petrosal sinus flow signal on three-dimensional time-of-flight MR angiography AJNR Am J Neuroradiol, 20 8 , 1476-81Ouanounou, S; Tomsick, T A; Heitsman, C; Holland, C K 1999. Cavernous sinus and inferior petrosal sinus flow signal on three-dimensional time-of-flight MR angiography. AJNR. American journal of neuroradiology, 20 8, 1476-81Holland, C K; Brown, J M; Scoutt, L M; Taylor, K J 1998. Lower extremity volumetric arterial blood flow in normal subjects. Ultrasound in medicine & biology, 24 8, 1079-86Holland, C. K.; Brown, J. M.; Scoutt, L. M.; Taylor, K. J. 1998. Lower extremity volumetric arterial blood flow in normal subjects Ultrasound Med Biol, 24 8 , 1079-86Deng, C. X.; Xu, Q.; Apfel, R. E.; Holland, C. K. 1996. In vitro measurements of inertial cavitation thresholds in human blood Ultrasound Med Biol, 22 7 , 939-48Deng, C. X.; Xu, Q.; Apfel, R. E.; Holland, C. K. 1996. Inertial cavitation produced by pulsed ultrasound in controlled host media J Acoust Soc Am, 100 2 Pt 1 , 1199-208Holland, C K; Clancy, M J; Taylor, K J; Alderman, J L; Purushothaman, K; McCauley, T R 1996. Volumetric flow estimation in vivo and in vitro using pulsed-Doppler ultrasound. Ultrasound in medicine & biology, 22 5, 591-603Holland, C K; Deng, C X; Apfel, R E; Alderman, J L; Fernandez, L A; Taylor, K J 1996. Direct evidence of cavitation in vivo from diagnostic ultrasound. Ultrasound in medicine & biology, 22 7, 917-25Holland, C. K.; Clancy, M. J.; Taylor, K. J.; Alderman, J. L.; Purushothaman, K.; McCauley, T. R. 1996. Volumetric flow estimation in vivo and in vitro using pulsed-Doppler ultrasound Ultrasound Med Biol, 22 5 , 591-603Holland, C. K.; Deng, C. X.; Apfel, R. E.; Alderman, J. L.; Fernandez, L. A.; Taylor, K. J. 1996. Direct evidence of cavitation in vivo from diagnostic ultrasound Ultrasound Med Biol, 22 7 , 917-25Brown, J. M.; Hammers, L. W.; Barton, J. W.; Holland, C. K.; Scoutt, L. M.; Pellerito, J. S.; Taylor, K. J. 1995. Quantitative Doppler assessment of acute scrotal inflammation Radiology, 197 2 , 427-31McCauley, T. R.; Pena, C. S.; Holland, C. K.; Price, T. B.; Gore, J. C. 1995. Validation of volume flow measurements with cine phase-contrast MR imaging for peripheral arterial waveforms J Magn Reson Imaging, 5 6 , 663-8Reinhold, C.; Hammers, L.; Taylor, C. R.; Quedens-Case, C. L.; Holland, C. K.; Taylor, K. J. 1995. Characterization of focal hepatic lesions with duplex sonography: findings in 198 patients AJR Am J Roentgenol, 164 5 , 1131-5Dillon, E. H.; Case, C. Q.; Ramos, I. M.; Holland, C. K.; Taylor, K. J. 1993. Endovaginal pulsed and color Doppler in first-trimester pregnancy Ultrasound Med Biol, 19 7 , 517-25Dillon, E. H.; Case, C. Q.; Ramos, I. M.; Holland, C. K.; Taylor, K. J. 1993. Endovaginal US and Doppler findings after first-trimester abortion Radiology, 186 1 , 87-91Holland, C. K. 1993. An ethnographic study of nursing culture as an exploration for determining the existence of a system of ritual J Adv Nurs, 18 9 , 1461-70Holland, C. K.; Taylor, K. J. 1993. Blood flow quantitation: waveform analysis, volume measurement, tumor flow, and the role of color imaging Clin Diagn Ultrasound, 28 2 , 125-39Crum, L. A.; Roy, R. A.; Dinno, M. A.; Church, C. C.; Apfel, R. E.; Holland, C. K.; Madanshetty, S. I. 1992. Acoustic cavitation produced by microsecond pulses of ultrasound: a discussion of some selected results J Acoust Soc Am, 91 2 , 1113-9Holland, C. K.; Roy, R. A.; Apfel, R. E.; Crum, L. A. 1992. In vitro detection of cavitation induced by a diagnostic ultrasound system IEEE Trans Ultrason Ferroelectr Freq Control, 39 1 , 95-101Apfel, R. E.; Holland, C. K. 1991. Gauging the likelihood of cavitation from short-pulse, low-duty cycle diagnostic ultrasound Ultrasound Med Biol, 17 2 , 179-85Holland, C. K.; Apfel, R. E. 1990. Thresholds for transient cavitation produced by pulsed ultrasound in a controlled nuclei environment J Acoust Soc Am, 88 5 , 2059-69Holland, C. K.; Apfel, R. E. 1989. An improved theory for the prediction of microcavitation thresholds IEEE Trans Ultrason Ferroelectr Freq Control, 36 2 , 204-8Atchley, A. A.; Frizzell, L. A.; Apfel, R. E.; Holland, C. K.; Madanshetty, S.; Roy, R. A. 1988. Thresholds for cavitation produced in water by pulsed ultrasound Ultrasonics, 26 5 , 280-5Lattwein K.;Shekhar H.;Van Wamel W.;Gonzalez T.;Herr A.;Holland C.;Kooiman K. 12-01-2018. An in vitro proof-of-principle study of sonobactericide Scientific Reports, 8 1, Krishnamoorthy M.K.;Roy-Chaudhury P.;Wang Y.;Holland C.K.;Rigger D.;Choe A.;Banerjee R.K. 12-01-2009. Vascular remodeling of arteriovenous fistula Proceedings of the ASME Summer Bioengineering Conference 2009, SBC2009, PART B, 1077-1078Kee P.;Abruzzo T.;Smith D.;Kopechek J.;Wang B.;Huang S.;MacDonald R.;Holland C.;McPherson D. 12-01-2008. Synthesis, acoustic stability, and pharmacologic activities of papaverine-loaded echogenic liposomes Journal of Liposome Research, 18 4, 263-277Holland C.;McPherson D. 11-17-2009. Echogenic lipsomes for targeted drug delivery Proceedings - 2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2009, , 755-758Haworth K.;Goldstein B.;Mercado-Shekhar K.;Holland C.;Redington A. 10-31-2017. Dissolved oxygen scavenging by acoustic droplet vaporization using intravascular ultrasound IEEE International Ultrasonics Symposium, IUS, , Haworth K.J.;Arunkumar P.;Goldstein B.H.;Su H.;Mercado-Shekhar K.P.;Privitera E.M.;Srivastava R.;Holland C.K.;Redington A.N. 10-31-2017. Dissolved oxygen scavenging by acoustic droplet vaporization using intravascular ultrasound IEEE International Ultrasonics Symposium, IUS, , Bader K.;Holland C. 10-28-2015. Development of a hybrid finite difference solution of the Westervelt equation using the fast nearfie AIP Conference Proceedings, 1685 , Britton G.;Kim H.;Kee P.;Aronowski J.;Holland C.;McPherson D.;Huang S. 10-19-2010. In vivo therapeutic gas delivery for neuroprotection with echogenic liposomes Circulation, 122 16, 1578-1587 Holland C.K.; Shekhar H.; Lafond M. 10-01-2019. Lipid-shelled microbubbles for ultrasound-triggered release of bioactive gases to treat stroke and c IEEE International Ultrasonics Symposium, IUS, 2019-October , 2037-2039Laing S.;Moody M.;Kim H.;Smulevitz B.;Huang S.;Holland C.;McPherson D.;Klegerman M. 10-01-2012. Thrombolytic efficacy of tissue plasminogen activator-loaded echogenic liposomes in a rabbit thrombu Thrombosis Research, 130 4, 629-635Mast T.;Salgaonkar V.;Karunakaran C.;Besse J.;Datta S.;Holland C. 09-24-2007. Measurements of cavitation dose, echogenicity, and temperature during ultrasound ablation AIP Conference Proceedings, 911 , 335-341 Hendley S.A.; Paul J.D.; Maxwell A.D.; Haworth K.J.; Holland C.K.; Bader K.B. 09-01-2021. Clot Degradation Under the Action of Histotripsy Bubble Activity and a Lytic Drug IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 68 9, 2942-2952Salgaonkar V.;Karunakaran C.;Besse J.;Heinlein G.;Datta S.;Holland C.;Mast T. 08-31-2007. Image-guided Ex vivo liver ablation by unfocused ultrasound using passive cavitation detection Progress in Biomedical Optics and Imaging - Proceedings of SPIE, 6440 , Karunakaran C.;Burgess M.;Holland C.;Mast T. 07-21-2009. Role of cavitation in bulk ultrasound ablation: A histologic study AIP Conference Proceedings, 1113 , 43-47Salgaonkar V.;Datta S.;Holland C.;Masta T. 07-21-2009. Passive imaging of cavitational acoustic emissions with ultrasound arrays AIP Conference Proceedings, 1113 , 73-77Cheng J.;Shaw G.;Holland C. 07-01-2005. In vitro microscopic imaging of enhanced thrombolysis with 120-kHz ultrasound in a human clot model Acoustic Research Letters Online, 6 3, 25-29Haworth K.;Salgaonkar V.;Corregan N.;Holland C.;Mast T. 06-19-2013. Spatial specificity and sensitivity of passive cavitation imaging for monitoring high-intensity focu Proceedings of Meetings on Acoustics, 19 , Zhou X.;Espy-Wilson C.Y.;Boyce S.;Tiede M.;Holland C.;Choe A. 06-17-2008. A magnetic resonance imaging-based articulatory and acoustic study of "retroflex" and "bunched" Amer Journal of the Acoustical Society of America, 123 6, 4466-4481 Haworth K.J.; Salido N.G.; Lafond M.; Escudero D.S.; Holland C.K. 06-01-2023. Passive Cavitation Imaging Artifact Reduction Using Data-Adaptive Spatial Filtering IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 70 6, 498-509Laing S.;Moody M.;Smulevitz B.;Kim H.;Kee P.;Huang S.;Holland C.;McPherson D. 06-01-2011. Ultrasound-enhanced thrombolytic effect of tissue plasminogen activator-loaded echogenic liposomes i Arteriosclerosis, Thrombosis, and Vascular Biology, 31 6, 1357-1359Laing S.;Kim H.;Kopechek J.;Parikh D.;Huang S.;Klegerman M.;Holland C.;McPherson D. 06-01-2010. Ultrasound-mediated delivery of echogenic immunoliposomes to porcine vascular smooth muscle cells in Journal of Liposome Research, 20 2, 160-167McPherson D.;Holland C. 05-07-2003. Seizing the science of ultrasound: Beyond imaging and into physiology and therapeutics Journal of the American College of Cardiology, 41 9, 1628-1630Haworth K.;Raymond J.;Radhakrishnan K.;Moody M.;Huang S.;Peng T.;Shekhar H.;Klegerman M.;Kim H.;McPherson D.;Holland C. 05-01-2016. Erratum to: "Trans-stent B-mode Ultrasound and Passive Cavitation Imaging" in Ultrasound Med Biol 20 Ultrasound in Medicine and Biology, 42 5, 1244Holland C. 04-01-2016. ACOUSTICAL NEWS-USA Journal of the Acoustical Society of America, 139 4, Tiukinhoy-Laing S.;Huang S.;Klegerman M.;Holland C.;McPherson D. 03-23-2007. Ultrasound-facilitated thrombolysis using tissue-plasminogen activator-loaded echogenic liposomes Thrombosis Research, 119 6, 777-784Klegerman M.;Wassler M.;Huang S.;Zou Y.;Kim H.;Shelat H.;Holland C.;Geng Y.;McPherson D. 03-19-2010. Liposomal modular complexes for simultaneous targeted delivery of bioactive gases and therapeutics Journal of Controlled Release, 142 3, 326-331Toepfer N.;Racadio J.;Adams J.;Babcock D.;Holland C. 03-01-2006. Aortic pseudothrombus: A sonographic artifact in the abdominal aorta Journal of Diagnostic Medical Sonography, 22 2, 131-134Shekhar H.;Smith N.;Raymond J.;Holland C. 02-01-2018. Effect of Temperature on the Size Distribution, Shell Properties, and Stability of Definity<sup&g Ultrasound in Medicine and Biology, 44 2, 434-446Herbst S.M.;Klegerman M.E.;Kim H.;Qi J.;Shelat H.;Wassler M.;Moody M.R.;Yang C.M.;Ge X.;Zou Y.;Kopechek J.A.;Clubb F.J.;Kraemer D.C.;Huang S.;Holland C.K.;McPherson D.D.;Geng Y.J. 02-01-2010. Delivery of stem cells to porcine arterial wall with echogenic liposomes conjugated to antibodies ag Molecular Pharmaceutics, 7 1, 3-11 Holland C.K. 01-01-2022. Editorial Ultrasound in Medicine and Biology, 48 1, 1-2 Maxwell A.D.; Haworth K.J.; Holland C.K.; Hendley S.A.; Kreider W.; Bader K.B. 01-01-2022. Design and Characterization of an Ultrasound Transducer for Combined Histotripsy-Thrombolytic Therap IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 69 1, 156-165 Kee P.H.; Moody M.R.; Huang S.L.; Kim H.; Yin X.; Peng T.; Laing S.T.; Klegerman M.E.; Rahbar M.H.; Vela D.; Genstler C.; Haworth K.J.; Holland C.K.; McPherson D.D. 01-01-2020. Stabilizing Peri-Stent Restenosis Using a Novel Therapeutic Carrier JACC: Basic to Translational Science, 5 1, 1-11 Lafond M.; Shekhar H.; Panmanee W.; Collins S.D.; Palaniappan A.; McDaniel C.T.; Hassett D.J.; Holland C.K. 01-01-2020. Bactericidal activity of lipid-shelled nitric oxide-loaded microbubbles Frontiers in Pharmacology, 10 , Bader K.;Haworth K.;Maxwell A.;Holland C. 01-01-2018. Post Hoc Analysis of Passive Cavitation Imaging for Classification of Histotripsy-Induced Liquefacti IEEE Transactions on Medical Imaging, 37 1, 106-115Haworth K.;Bader K.;Rich K.;Holland C.;Mast T. 01-01-2017. Quantitative frequency-domain passive cavitation imaging IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 64 1, 177-191Mukherjee P.;Kandadai M.;Shaw G.;Holland C.;Papautsky I. 01-01-2015. Generation of drug loaded echogenic liposomes using microfluidic hydrodynamic focusing MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, , 466-468Ferrara K.;Griffin R.;Guha C.;Holland C.;Lafon C. 01-01-2013. TU?E?144?01: Advanced Novel Technologies & Therapeutic Strategies Medical Physics, 40 6, 451Holland C.;Shaw G.;Datta S. 01-01-2010. Ultrasound-enhanced thrombolysis Therapeutic Ultrasound: Mechanisms to Applications, , 239-260Fowlkes J.B.;Abramowicz J.S.;Church C.C.;Holland C.K.;Miller D.L.;O'Brien W.D.;Sanghvi N.T.;Stratmeyer M.E.;Zachary J.F.;Deng C.X.;Harris G.R.;Herman B.A.;Hynynen K.H.;Merritt C.R.B.;Thomenius K.E.;Bailey M.R.;Carson P.L.;Carstensen E.L.;Frizzell L.A.;Nyborg W.L.;Barnett S.B.;Duck F.A.;Edmonds P.D.;Ziskin M.C.;Abbott J.G.;Dalecki D.;Dunn F.;Greenleaf J.F.;Salvesen K.A.;Siddiqi T.A.;Averkiou M.A.;Brayman A.A.;Everbach E.C.;Wible J.H.;Wu J.;Simpson D.G. 01-01-2008. American Institute of Ultrasound in Medicine consensus report on potential bioeffects of diagnostic Journal of Ultrasound in Medicine, 27 4, 503-515Miller D.L.;Averkiou M.A.;Brayman A.A.;Everbach E.C.;Holland C.K.;Wible J.H.;Wu J. 01-01-2008. Bioeffects considerations for diagnostic ultrasound contrast agents Journal of Ultrasound in Medicine, 27 4, 611-632Holland C. 01-01-2007. Online review facilitates rapid publishing Ultrasound in Medicine and Biology, 33 1, 1-2Cheng J.;Shaw G.;Holland C. 01-01-2005. In vitro microscopic imaging of enhanced thrombolysis with 120-kHz ultrasound in a human clot model Acoustic Research Letters Online, 6 1, 25-29Holland C.;Everbach E. 01-01-2005. Guest editorial: Sono et Gravitas - The legacy of Robert Edmund Apfel Acoustic Research Letters Online, 6 3, Taylor C.;Holland C. 01-01-2003. Kenneth J. Taylor, MD, PhD, FACP, 1939-2003, pioneer of diagnostic ultrasound imaging. Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 22 6, 663-664Fowlkes J.;Holland C. 01-01-2000. Mechanical bioeffects from diagnostic ultrasound: AIUM consensus statements. American Institute of U Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 19 2, 69-72Fowlkes J.;Holland C.;Kremkau F. 01-01-2000. Mechanical bioeffects from diagnostic ultrasound: AIUM consensus statements Journal of Ultrasound in Medicine, 19 2, 68-168Deng C.;Xu Q.;Apfel R.;Holland C. 01-01-1996. Inertial cavitation produced by pulsed ultrasound in controlled host media Journal of the Acoustical Society of America, 100 2 I, 1199-1208Deng C.;Xu Q.;Apfel R.;Holland C. 01-01-1996. In vitro measurements of inertial cavitation thresholds in human blood Ultrasound in Medicine and Biology, 22 7, 939-948Brown J.M.;Hammers L.W.;Barton J.W.;Holland C.K.;Scoutt L.M.;Pellerito J.S.;Taylor K.J.W. 01-01-1995. Quantitative Doppler assessment of acute scrotal inflammation Radiology, 197 2, 427-431McCauley T.R.;Pena C.S.;Holland C.K.;Price T.B.;Gore J.C. 01-01-1995. Validation of volume flow measurements with cine phase?contrast MR imaging for peripheral arterial w Journal of Magnetic Resonance Imaging, 5 6, 663-668Reinhold C.;Hammers L.;Taylor C.;Quedens-Case C.;Holland C.;Taylor K. 01-01-1995. Characterization of focal hepatic lesions with duplex sonography: Findings in 198 patients American Journal of Roentgenology, 164 5, 1131-1135Dillon E.;Case C.;Ramos I.;Holland C.;Taylor K. 01-01-1993. Endovaginal pulsed and color doppler in first-trimester pregnancy Ultrasound in Medicine and Biology, 19 7, 517-525Dillon E.;Case C.;Ramos I.;Holland C.;Taylor K. 01-01-1993. Endovaginal US and Doppler findings after first-trimester abortion Radiology, 186 1, 87-91Holland C.;Taylor K. 01-01-1993. Blood flow quantitation: waveform analysis, volume measurement, tumor flow, and the role of color im Clinics in diagnostic ultrasound, 28 , 125-139Crum L.;Roy R.;Dinno M.;Church C.;Apfel R.;Holland C.;Madanshetty S. 01-01-1992. Acoustic cavitation produced by microsecond pulses of ultrasound: A discussion of some selected resu Journal of the Acoustical Society of America, 91 2, 1113-1119Holland C.;Roy R.;Apfel R.;Crum L. 01-01-1992. In Vitro Detection of Cavitation Induced by a Diagnostic Ultrasound System IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 39 1, 95-101Apfel R.;Holland C. 01-01-1991. Gauging the likelihood of cavitation from short-pulse, low-duty cycle diagnostic ultrasound Ultrasound in Medicine and Biology, 17 2, 179-185Holland C.;Apfel R. 01-01-1990. Thresholds for transient cavitation produced by pulsed ultrasound in a controlled nuclei environment Journal of the Acoustical Society of America, 88 5, 2059-2069Holland C. 01-01-1989. Thresholds of transient cavitation produced by pulsed ultrasound in a controlled nuclei environment Journal of the Acoustical Society of America, 86 2, 844Holland C.;Apfel R. 01-01-1989. An Improved Theory for the Prediction of Microcavitation Thresholds IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 36 2, 204-208Atchley A.;Frizzell L.;Apfel R.;Holland C.;Madanshetty S.;Roy R. 01-01-1988. Thresholds for cavitation produced in water by pulsed ultrasound Ultrasonics, 26 5, 280-285Bhatt, Seema R; Eckerle, Michelle D; Reed, Jennifer L; Robinson, Venita; Brown, Angela; Lippe, Joyce; Holland, Carolyn; Iyer, Srikant . Implementation of Targeted Point of Care HIV Testing in a Pediatric Emergency Department. Pediatric quality & safety, 5 1, e248
Escudero, Daniel Suarez; Lafond, Maxime; Salido, Nuria G; Haworth, Kevin J; Hannah, Alexander S; Macke, Gregory P; Genstler, Curtis; Holland, Christy K 2023. Corrigendum to 'Cavitation emissions nucleated by Definity infused through an EkoSonic catheter in a flow phantom' [Ultrasound in Med & Biol. 47 (2021) 693-709]. Ultrasound in medicine & biology, 49 1, 410-414Kennedy, Sonya R; Lafond, Maxime; Haworth, Kevin J; Escudero, Daniel Suarez; Ionascu, Dan; Frierson, Brion; Huang, Shaoling; Klegerman, Melvin E; Peng, Tao; McPherson, David D; Genstler, Curtis; Holland, Christy K 2023. Initiating and imaging cavitation from infused echo contrast agents through the EkoSonic catheter. Scientific reports, 13 1, 6191Kleven, Robert T; Huang, Shenwen; Ford, Samantha M; Sakthivel, Karthikeyan; Thomas, Seth R; Zuccarello, Mario; Herr, Andrew B; Holland, Christy K 2023. Effect of Recombinant Tissue Plasminogen Activator and 120-kHz Ultrasound on Porcine Intracranial Thrombus Density. Ultrasound in medicine & biology, 49 2, 539-548Suarez Escudero, Daniel; Haworth, Kevin J; Genstler, Curtis; Holland, Christy K 2023. Quantifying the Effect of Acoustic Parameters on Temporal and Spatial Cavitation Activity: Gauging Cavitation Dose. Ultrasound in medicine & biology, 49 11, 2388-2397Hendley, Samuel A; Bhargava, Aarushi; Holland, Christy K; Wool, Geoffrey D; Ahmed, Osman; Paul, Jonathan D; Bader, Kenneth B 2022. (More than) doubling down: Effective fibrinolysis at a reduced rt-PA dose for catheter-directed thrombolysis combined with histotripsy. PloS one, 17 1, e0261567Klegerman, Melvin E; Moody, Melanie R; Huang, Shao-Ling; Peng, Tao; Laing, Susan T; Govindarajan, Vijay; Danila, Delia; Tahanan, Amirali; Rahbar, Mohammad H; Vela, Deborah; Genstler, Curtis; Haworth, Kevin J; Holland, Christy K; McPherson, David D; Kee, Patrick H 2022. Demonstration of ultrasound-mediated therapeutic delivery of fibrin-targeted pioglitazone-loaded echogenic liposomes into the arterial bed for attenuation of peri-stent restenosis. Journal of drug targeting, , 1-10Zemzemi, Chadi; Phillips, Matthew; Vela, Deborah C; Hilvert, Nicole A; Racadio, John M; Bader, Kenneth B; Haworth, Kevin J; Holland, Christy K 2022. Effect of Thrombin and Incubation Time on Porcine Whole Blood Clot Elasticity and Recombinant Tissue Plasminogen Activator Susceptibility. Ultrasound in medicine & biology, 48 8, 1567-1578Karunakaran, Chandra Priya; Burgess, Mark T; Rao, Marepalli B; Holland, Christy K; Mast, T Douglas 2021. Effect of Overpressure on Acoustic Emissions and Treated Tissue Histology in ex Vivo Bulk Ultrasound Ablation. Ultrasound in medicine & biology, 47 8, 2360-2376Kleven, Robert T; Karani, Kunal B; Hilvert, Nicole; Ford, Samantha M; Mercado-Shekhar, Karla P; Racadio, John M; Rao, Marepalli B; Abruzzo, Todd A; Holland, Christy K 2021. Accelerated sonothrombolysis with Definity in a xenographic porcine cerebral thromboembolism model. Scientific reports, 11 1, 3987Lafond, Maxime; Salido, Nuria G; Haworth, Kevin J; Hannah, Alexander S; Macke, Gregory P; Genstler, Curtis; Holland, Christy K 2021. Cavitation Emissions Nucleated by Definity Infused through an EkoSonic Catheter in a Flow Phantom. Ultrasound in medicine & biology, 47 3, 693-709Bollen, Viktor; Hendley, Samuel A; Paul, Jonathan D; Maxwell, Adam D; Haworth, Kevin J; Holland, Christy K; Bader, Kenneth B 2020. In Vitro Thrombolytic Efficacy of Single- and Five-Cycle Histotripsy Pulses and rt-PA. Ultrasound in medicine & biology, 46 2, 336-349Kee, Patrick H; Moody, Melanie R; Huang, Shao-Ling; Kim, Hyunggun; Yin, Xing; Peng, Tao; Laing, Susan T; Klegerman, Melvin E; Rahbar, Mohammad H; Vela, Deborah; Genstler, Curtis; Haworth, Kevin J; Holland, Christy K; McPherson, David D 2020. Stabilizing Peri-Stent Restenosis Using a Novel Therapeutic Carrier. JACC. Basic to translational science, 5 1, 1-11Kooiman, Klazina; Roovers, Silke; Langeveld, Simone A G; Kleven, Robert T; Dewitte, Heleen; O'Reilly, Meaghan A; Escoffre, Jean-Michel; Bouakaz, Ayache; Verweij, Martin D; Hynynen, Kullervo; Lentacker, Ine; Stride, Eleanor; Holland, Christy K 2020. Ultrasound-Responsive Cavitation Nuclei for Therapy and Drug Delivery. Ultrasound in medicine & biology, 46 6, 1296-1325Lattwein, Kirby R; Shekhar, Himanshu; Kouijzer, Joop J P; van Wamel, Willem J B; Holland, Christy K; Kooiman, Klazina 2020. Sonobactericide: An Emerging Treatment Strategy for Bacterial Infections. Ultrasound in medicine & biology, 46 2, 193-215Bader, Kenneth B; Gruber, Matthew J; Holland, Christy K 2019. Corrigendum to: "Shaken and Stirred: Mechanisms of Ultrasound-Enhanced Thrombolysis" in Ultrasound Med Biol 2015; 41(1): 187-196. Ultrasound in medicine & biology, 45 8, 2266Kleven, Robert T; Karani, Kunal B; Salido, Nuria G; Shekhar, Himanshu; Haworth, Kevin J; Mast, T Douglas; Tadesse, Dawit G; Holland, Christy K 2019. The effect of 220?kHz insonation scheme on rt-PA thrombolytic efficacy in vitro. Physics in medicine and biology, 64 16, 165015Lafond, Maxime; Shekhar, Himanshu; Panmanee, Warunya; Collins, Sydney D; Palaniappan, Arunkumar; McDaniel, Cameron T; Hassett, Daniel J; Holland, Christy K 2019. Bactericidal Activity of Lipid-Shelled Nitric Oxide-Loaded Microbubbles. Frontiers in pharmacology, 10 , 1540Mercado-Shekhar, Karla P; Kleven, Robert; Rivera, Hermes Aponte; Lewis, Ryden; Karani, Kunal B; Vos, Hendrik J; Abruzzo, Todd A; Haworth, Kevin J; Holland, Christy K 2019. Erratum to 'Effect of clot stiffness on recombinant tissue plasminogen activator lytic susceptibility in vitro' [Ultrasound Med Biol 44 (2018) 2710-2727]. Ultrasound in medicine & biology, 45 7, 1860Mercado-Shekhar, Karla P; Su, Haili; Kalaikadal, Deepak S; Lorenz, John N; Manglik, Raj M; Holland, Christy K; Redington, Andrew N; Haworth, Kevin J 2019. Acoustic droplet vaporization-mediated dissolved oxygen scavenging in blood-mimicking fluids, plasma, and blood. Ultrasonics sonochemistry, 56 , 114-124Shekhar, Himanshu; Kleven, Robert T; Peng, Tao; Palaniappan, Arunkumar; Karani, Kunal B; Huang, Shaoling; McPherson, David D; Holland, Christy K 2019. In vitro characterization of sonothrombolysis and echocontrast agents to treat ischemic stroke. Scientific reports, 9 1, 9902Shekhar, Himanshu; Palaniappan, Arunkumar; Peng, Tao; Lafond, Maxime; Moody, Melanie R; Haworth, Kevin J; Huang, Shaoling; McPherson, David D; Holland, Christy K 2019. Characterization and Imaging of Lipid-Shelled Microbubbles for Ultrasound-Triggered Release of Xenon. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 16 3, 878-890Lattwein, Kirby R; Shekhar, Himanshu; van Wamel, Willem J B; Gonzalez, Tammy; Herr, Andrew B; Holland, Christy K; Kooiman, Klazina 2018. An in vitro proof-of-principle study of sonobactericide. Scientific reports, 8 1, 3411Mercado-Shekhar, Karla P; Kleven, Robert T; Aponte Rivera, Hermes; Lewis, Ryden; Karani, Kunal B; Vos, Hendrik J; Abruzzo, Todd A; Haworth, Kevin J; Holland, Christy K 2018. Effect of Clot Stiffness on Recombinant Tissue Plasminogen Activator Lytic Susceptibility in Vitro. Ultrasound in medicine & biology, 44 12, 2710-2727Rich, Kyle T; Holland, Christy K; Rao, Marepalli B; Mast, T Douglas 2018. Characterization of cavitation-radiated acoustic power using diffraction correction. The Journal of the Acoustical Society of America, 144 6, 3563Shekhar, Himanshu; Smith, Nathaniel J; Raymond, Jason L; Holland, Christy K 2018. Effect of Temperature on the Size Distribution, Shell Properties, and Stability of Definity®. Ultrasound in medicine & biology, 44 2, 434-446Beigel, John H; Tebas, Pablo; Elie-Turenne, Marie-Carmelle; Bajwa, Ednan; Bell, Todd E; Cairns, Charles B; Shoham, Shmuel; Deville, Jaime G; Feucht, Eric; Feinberg, Judith; Luke, Thomas; Raviprakash, Kanakatte; Danko, Janine; O'Neil, Dorothy; Metcalf, Julia A; King, Karen; Burgess, Timothy H; Aga, Evgenia; Lane, H Clifford; Hughes, Michael D; Davey, Richard T 2017. Immune plasma for the treatment of severe influenza: an open-label, multicentre, phase 2 randomised study. The Lancet. Respiratory medicine, 5 6, 500-511Haworth, Kevin J; Goldstein, Bryan H; Mercado-Shekhar, Karla P; Srivastava, Rohan; Arunkumar, P; Su, Haili; Privitera, Ellena M; Holland, Christy K; Redington, Andrew N 2017. Dissolved Oxygen Scavenging by Acoustic Droplet Vaporization using Intravascular Ultrasound. IEEE International Ultrasonics Symposium : [proceedings]. IEEE International Ultrasonics Symposium, 2017 , Huang, Shenwen; Shekhar, Himanshu; Holland, Christy K 2017. Comparative lytic efficacy of rt-PA and ultrasound in porcine versus human clots. PloS one, 12 5, e0177786Shekhar, Himanshu; Bader, Kenneth B; Huang, Shenwen; Peng, Tao; Huang, Shaoling; McPherson, David D; Holland, Christy K 2017. In vitro thrombolytic efficacy of echogenic liposomes loaded with tissue plasminogen activator and octafluoropropane gas. Physics in medicine and biology, 62 2, 517-538Bader, Kenneth B; Bouchoux, Guillaume; Holland, Christy K 2016. Sonothrombolysis. Advances in experimental medicine and biology, 880 , 339-62Bader, Kenneth B; Crowe, Michael J; Raymond, Jason L; Holland, Christy K 2016. Effect of Frequency-Dependent Attenuation on Predicted Histotripsy Waveforms in Tissue-Mimicking Phantoms. Ultrasound in medicine & biology, 42 7, 1701-5Bader, Kenneth B; Haworth, Kevin J; Shekhar, Himanshu; Maxwell, Adam D; Peng, Tao; McPherson, David D; Holland, Christy K 2016. Efficacy of histotripsy combined with rt-PA in vitro. Physics in medicine and biology, 61 14, 5253-74Bader, Kenneth B; Holland, Christy K 2016. Predicting the growth of nanoscale nuclei by histotripsy pulses. Physics in medicine and biology, 61 7, 2947-66Haworth, Kevin J; Raymond, Jason L; Radhakrishnan, Kirthi; Moody, Melanie R; Huang, Shao-Ling; Peng, Tao; Shekhar, Himanshu; Klegerman, Melvin E; Kim, Hyunggun; McPherson, David D; Holland, Christy K 2016. Erratum to: "Trans-stent B-mode Ultrasound and Passive Cavitation Imaging" in Ultrasound Med Biol 2016;42(2):518-527. Ultrasound in medicine & biology, 42 5, 1244Haworth, Kevin J; Raymond, Jason L; Radhakrishnan, Kirthi; Moody, Melanie R; Huang, Shao-Ling; Peng, Tao; Shekhar, Himanshu; Klegerman, Melvin E; Kim, Hyunggun; McPherson, David D; Holland, Christy K 2016. Trans-Stent B-Mode Ultrasound and Passive Cavitation Imaging. Ultrasound in medicine & biology, 42 2, 518-27Kandadai, Madhuvanthi A; Mukherjee, Prithviraj; Shekhar, Himanshu; Shaw, George J; Papautsky, Ian; Holland, Christy K 2016. Microfluidic manufacture of rt-PA -loaded echogenic liposomes. Biomedical microdevices, 18 3, 48Klegerman, Melvin E; Naji, Ali K; Haworth, Kevin J; Zou, Yuejiao; Golunski, Eva; Peng, Tao; Britton, George L; Huang, Shao-Ling; Holland, Christy K; McPherson, David D 2016. Ultrasound-enhanced bevacizumab release from echogenic liposomes for inhibition of atheroma progression. Journal of liposome research, 26 1, 47-56Radhakrishnan, Kirthi; Holland, Christy K; Haworth, Kevin J 2016. Scavenging dissolved oxygen via acoustic droplet vaporization. Ultrasonics sonochemistry, 31 , 394-403Raymond, Jason L; Luan, Ying; Peng, Tao; Huang, Shao-Ling; McPherson, David D; Versluis, Michel; de Jong, Nico; Holland, Christy K 2016. Loss of gas from echogenic liposomes exposed to pulsed ultrasound. Physics in medicine and biology, 61 23, 8321-8339Sutton, J T; Haworth, K J; Shanmukhappa, S K; Moody, M R; Klegerman, M E; Griffin, J K; Patton, D M; McPherson, D D; Holland, C K 2016. Delivery of bevacizumab to atheromatous porcine carotid tissue using echogenic liposomes. Drug delivery, 23 9, 3594-3605Bader, Kenneth B; Bouchoux, Guillaume; Peng, Tao; Klegerman, Melvin E; McPherson, David D; Holland, Christy K 2015. Thrombolytic efficacy and enzymatic activity of rt-PA-loaded echogenic liposomes. Journal of thrombosis and thrombolysis, , Bader, Kenneth B; Gruber, Matthew J; Holland, Christy K 2015. Shaken and stirred: mechanisms of ultrasound-enhanced thrombolysis. Ultrasound in medicine & biology, 41 1, 187-96Haworth, Kevin J; Salgaonkar, Vasant A; Corregan, Nicholas M; Holland, Christy K; Mast, T Douglas 2015. Using Passive Cavitation Images to Classify High-Intensity Focused Ultrasound Lesions. Ultrasound in medicine & biology, 41 9, 2420-34Holland, C 2015. WE-D-210-03: Microbubble Pumps: Â Ultrasound Theragnostic Agents. Medical physics, 42 6, 3672Kandadai, Madhuvanthi A; Meunier, Jason M; Hart, Kimberley; Holland, Christy K; Shaw, George J 2015. Plasmin-loaded echogenic liposomes for ultrasound-mediated thrombolysis. Translational stroke research, 6 1, 78-87Radhakrishnan, Kirthi; Haworth, Kevin J; Peng, Tao; McPherson, David D; Holland, Christy K 2015. Loss of echogenicity and onset of cavitation from echogenic liposomes: pulse repetition frequency independence. Ultrasound in medicine & biology, 41 1, 208-21Raymond, Jason L; Luan, Ying; van Rooij, Tom; Kooiman, Klazina; Huang, Shao-Ling; McPherson, David D; Versluis, Michel; de Jong, Nico; Holland, Christy K 2015. Impulse response method for characterization of echogenic liposomes. The Journal of the Acoustical Society of America, 137 4, 1693-703Bouchoux, Guillaume; Shivashankar, Ravishankar; Abruzzo, Todd A; Holland, Christy K 2014. In silico study of low-frequency transcranial ultrasound fields in acute ischemic stroke patients. Ultrasound in medicine & biology, 40 6, 1154-66Gruber, Matthew J; Bader, Kenneth B; Holland, Christy K 2014. Cavitation thresholds of contrast agents in an in vitro human clot model exposed to 120-kHz ultrasound. The Journal of the Acoustical Society of America, 135 2, 646-53Haworth, Kevin J; Weidner, Christopher R; Abruzzo, Todd A; Shearn, Jason T; Holland, Christy K 2014. Mechanical properties and fibrin characteristics of endovascular coil-clot complexes: relevance to endovascular cerebral aneurysm repair paradigms. Journal of neurointerventional surgery, , Kim, Hyunggun; Britton, George L; Peng, Tao; Holland, Christy K; McPherson, David D; Huang, Shao-Ling 2014. Nitric oxide-loaded echogenic liposomes for treatment of vasospasm following subarachnoid hemorrhage. International journal of nanomedicine, 9 , 155-65Raymond, Jason L; Haworth, Kevin J; Bader, Kenneth B; Radhakrishnan, Kirthi; Griffin, Joseph K; Huang, Shao-Ling; McPherson, David D; Holland, Christy K 2014. Broadband attenuation measurements of phospholipid-shelled ultrasound contrast agents. Ultrasound in medicine & biology, 40 2, 410-21Sutton, J T; Raymond, J L; Verleye, M C; Pyne-Geithman, G J; Holland, C K 2014. Pulsed ultrasound enhances the delivery of nitric oxide from bubble liposomes to ex vivo porcine carotid tissue. International journal of nanomedicine, 9 , 4671-83Bader, K. B.; Holland, C. K. 2013. Gauging the likelihood of stable cavitation from ultrasound contrast agents Phys Med Biol, 58 1 , 127-44Bader, Kenneth B; Holland, Christy K 2013. Gauging the likelihood of stable cavitation from ultrasound contrast agents. Physics in medicine and biology, 58 1, 127-44Haworth, K. J.; Salgaonkar, V. A.; Corregan, N. M.; Holland, C. K.; Mast, T. D. 2013. Spatial specificity and sensitivity of passive cavitation imaging for monitoring high-intensity focused ultrasound thermal ablation in ex vivo bovine liver J Acoust Soc Am, 133 5 , 3263Kopechek, J. A.; Haworth, K. J.; Radhakrishnan, K.; Huang, S. L.; Klegerman, M. E.; McPherson, D. D.; Holland, C. K. 2013. The impact of bubbles on measurement of drug release from echogenic liposomes Ultrason Sonochem, 20 4 , 1121-30Kopechek, Jonathan A; Haworth, Kevin J; Radhakrishnan, Kirthi; Huang, Shao-Ling; Klegerman, Melvin E; McPherson, David D; Holland, Christy K 2013. The impact of bubbles on measurement of drug release from echogenic liposomes. Ultrasonics sonochemistry, 20 4, 1121-30Radhakrishnan, Kirthi; Bader, Kenneth B; Haworth, Kevin J; Kopechek, Jonathan A; Raymond, Jason L; Huang, Shao-Ling; McPherson, David D; Holland, Christy K 2013. Relationship between cavitation and loss of echogenicity from ultrasound contrast agents. Physics in medicine and biology, 58 18, 6541-63Sutton, J. T.; Ivancevich, N. M.; Perrin, S. R., Jr.; Vela, D. C.; Holland, C. K. 2013. Clot retraction affects the extent of ultrasound-enhanced thrombolysis in an ex vivo porcine thrombosis model Ultrasound Med Biol, 39 5 , 813-24Sutton, J. T.; Haworth, K. J.; Pyne-Geithman, G.; Holland, C. K. 2013. Ultrasound-mediated drug delivery for cardiovascular disease Expert Opin Drug Deliv, 10 5 , 573-92Sutton, Jonathan T; Haworth, Kevin J; Pyne-Geithman, Gail; Holland, Christy K 2013. Ultrasound-mediated drug delivery for cardiovascular disease. Expert opinion on drug delivery, 10 5, 573-92Sutton, Jonathan T; Ivancevich, Nikolas M; Perrin, Stephen R; Vela, Deborah C; Holland, Christy K 2013. Clot retraction affects the extent of ultrasound-enhanced thrombolysis in an ex vivo porcine thrombosis model. Ultrasound in medicine & biology, 39 5, 813-24Bouchoux, G.; Bader, K. B.; Korfhagen, J. J.; Raymond, J. L.; Shivashankar, R.; Abruzzo, T. A.; Holland, C. K. 2012. Experimental validation of a finite-difference model for the prediction of transcranial ultrasound fields based on CT images Phys Med Biol, 57 23 , 8005-22Bouchoux, Guillaume; Bader, Kenneth B; Korfhagen, Joseph J; Raymond, Jason L; Shivashankar, Ravishankar; Abruzzo, Todd A; Holland, Christy K 2012. Experimental validation of a finite-difference model for the prediction of transcranial ultrasound fields based on CT images. Physics in medicine and biology, 57 23, 8005-22Haworth, K. J.; Mast, T. D.; Radhakrishnan, K.; Burgess, M. T.; Kopechek, J. A.; Huang, S. L.; McPherson, D. D.; Holland, C. K. 2012. Passive imaging with pulsed ultrasound insonations J Acoust Soc Am, 132 1 , 544-53Haworth, Kevin J; Mast, T Douglas; Radhakrishnan, Kirthi; Burgess, Mark T; Kopechek, Jonathan A; Huang, Shao-Ling; McPherson, David D; Holland, Christy K 2012. Passive imaging with pulsed ultrasound insonations. The Journal of the Acoustical Society of America, 132 1, 544-53Huppert, Jill S; Reed, Jennifer L; Munafo, Jennifer Knopf; Ekstrand, Rachel; Gillespie, Gordon; Holland, Carolyn; Britto, Maria T 2012. Improving notification of sexually transmitted infections: a quality improvement project and planned experiment. Pediatrics, 130 2, e415-22Laing, S. T.; Moody, M. R.; Kim, H.; Smulevitz, B.; Huang, S. L.; Holland, C. K.; McPherson, D. D.; Klegerman, M. E. 2012. Thrombolytic efficacy of tissue plasminogen activator-loaded echogenic liposomes in a rabbit thrombus model Thromb Res, 130 4 , 629-35Radhakrishnan, K.; Haworth, K. J.; Huang, S. L.; Klegerman, M. E.; McPherson, D. D.; Holland, C. K. 2012. Stability of echogenic liposomes as a blood pool ultrasound contrast agent in a physiologic flow phantom Ultrasound Med Biol, 38 11 , 1970-81Radhakrishnan, Kirthi; Haworth, Kevin J; Huang, Shao-Ling; Klegerman, Melvin E; McPherson, David D; Holland, Christy K 2012. Stability of echogenic liposomes as a blood pool ultrasound contrast agent in a physiologic flow phantom. Ultrasound in medicine & biology, 38 11, 1970-81Hitchcock, K. E.; Ivancevich, N. M.; Haworth, K. J.; Caudell Stamper, D. N.; Vela, D. C.; Sutton, J. T.; Pyne-Geithman, G. J.; Holland, C. K. 2011. Ultrasound-enhanced rt-PA thrombolysis in an ex vivo porcine carotid artery model Ultrasound Med Biol, 37 8 , 1240-51Hitchcock, Kathryn E; Ivancevich, Nikolas M; Haworth, Kevin J; Caudell Stamper, Danielle N; Vela, Deborah C; Sutton, Jonathan T; Pyne-Geithman, Gail J; Holland, Christy K 2011. Ultrasound-enhanced rt-PA thrombolysis in an ex vivo porcine carotid artery model. Ultrasound in medicine & biology, 37 8, 1240-51Kopechek, J. A.; Haworth, K. J.; Raymond, J. L.; Douglas Mast, T.; Perrin, S. R.; Klegerman, M. E.; Huang, S.; Porter, T. M.; McPherson, D. D.; Holland, C. K. 2011. Acoustic characterization of echogenic liposomes: frequency-dependent attenuation and backscatter J Acoust Soc Am, 130 5 , 3472-81Kopechek, Jonathan A; Haworth, Kevin J; Raymond, Jason L; Douglas Mast, T; Perrin, Stephen R; Klegerman, Melvin E; Huang, Shaoling; Porter, Tyrone M; McPherson, David D; Holland, Christy K 2011. Acoustic characterization of echogenic liposomes: frequency-dependent attenuation and backscatter. The Journal of the Acoustical Society of America, 130 5, 3472-81Laing, S. T.; Moody, M.; Smulevitz, B.; Kim, H.; Kee, P.; Huang, S.; Holland, C. K.; McPherson, D. D. 2011. Ultrasound-enhanced thrombolytic effect of tissue plasminogen activator-loaded echogenic liposomes in an in vivo rabbit aorta thrombus model--brief report Arterioscler Thromb Vasc Biol, 31 6 , 1357-9Meunier, J. M.; Holland, C. K.; Porter, T. M.; Lindsell, C. J.; Shaw, G. J. 2011. Combination treatment with rt-PA is more effective than rt-PA alone in an in vitro human clot model Curr Neurovasc Res, 8 4 , 305-12Meunier, Jason M; Holland, Christy K; Porter, Tyrone M; Lindsell, Christopher J; Shaw, George J 2011. Combination treatment with rt-PA is more effective than rt-PA alone in an in vitro human clot model. Current neurovascular research, 8 4, 305-12Britton, G. L.; Kim, H.; Kee, P. H.; Aronowski, J.; Holland, C. K.; McPherson, D. D.; Huang, S. L. 2010. In vivo therapeutic gas delivery for neuroprotection with echogenic liposomes Circulation, 122 16 , 1578-87Herbst, S. M.; Klegerman, M. E.; Kim, H.; Qi, J.; Shelat, H.; Wassler, M.; Moody, M. R.; Yang, C. M.; Ge, X.; Zou, Y.; Kopechek, J. A.; Clubb, F. J.; Kraemer, D. C.; Huang, S.; Holland, C. K.; McPherson, D. D.; Geng, Y. J. 2010. Delivery of stem cells to porcine arterial wall with echogenic liposomes conjugated to antibodies against CD34 and intercellular adhesion molecule-1 Mol Pharm, 7 1 , 3-11Hitchcock, K. E.; Caudell, D. N.; Sutton, J. T.; Klegerman, M. E.; Vela, D.; Pyne-Geithman, G. J.; Abruzzo, T.; Cyr, P. E.; Geng, Y. J.; McPherson, D. D.; Holland, C. K. 2010. Ultrasound-enhanced delivery of targeted echogenic liposomes in a novel ex vivo mouse aorta model J Control Release, 144 3 , 288-95Hitchcock, K. E.; Holland, C. K. 2010. Ultrasound-assisted thrombolysis for stroke therapy: better thrombus break-up with bubbles Stroke, 41 10 Suppl , S50-3Hitchcock, Kathryn E; Caudell, Danielle N; Sutton, Jonathan T; Klegerman, Melvin E; Vela, Deborah; Pyne-Geithman, Gail J; Abruzzo, Todd; Cyr, Peppar E P; Geng, Yong-Jian; McPherson, David D; Holland, Christy K 2010. Ultrasound-enhanced delivery of targeted echogenic liposomes in a novel ex vivo mouse aorta model. Journal of controlled release : official journal of the Controlled Release Society, 144 3, 288-95Hitchcock, Kathryn E; Holland, Christy K 2010. Ultrasound-assisted thrombolysis for stroke therapy: better thrombus break-up with bubbles. Stroke; a journal of cerebral circulation, 41 10 Suppl, S50-3Klegerman, M. E.; Wassler, M.; Huang, S. L.; Zou, Y.; Kim, H.; Shelat, H. S.; Holland, C. K.; Geng, Y. J.; McPherson, D. D. 2010. Liposomal modular complexes for simultaneous targeted delivery of bioactive gases and therapeutics J Control Release, 142 3 , 326-31Kopechek, J. A.; Kim, H.; McPherson, D. D.; Holland, C. K. 2010. Calibration of the 1-MHz Sonitron ultrasound system Ultrasound Med Biol, 36 10 , 1762-6Kopechek, Jonathan A; Kim, Hyunggun; McPherson, David D; Holland, Christy K 2010. Calibration of the 1-MHz Sonitron ultrasound system. Ultrasound in medicine & biology, 36 10, 1762-6Laing, S. T.; Kim, H.; Kopechek, J. A.; Parikh, D.; Huang, S.; Klegerman, M. E.; Holland, C. K.; McPherson, D. D. 2010. Ultrasound-mediated delivery of echogenic immunoliposomes to porcine vascular smooth muscle cells in vivo J Liposome Res, 20 2 , 160-7Shaw, G. J.; Meunier, J. M.; Lindsell, C. J.; Pancioli, A. M.; Holland, C. K. 2010. Making the right choice: optimizing rt-PA and eptifibatide lysis, an in vitro study Thromb Res, 126 4 , e305-11Shaw, George J; Meunier, Jason M; Lindsell, Christopher J; Pancioli, Arthur M; Holland, Christy K 2010. Making the right choice: optimizing rt-PA and eptifibatide lysis, an in vitro study. Thrombosis research, 126 4, e305-11Smith, D. A.; Vaidya, S. S.; Kopechek, J. A.; Huang, S. L.; Klegerman, M. E.; McPherson, D. D.; Holland, C. K. 2010. Ultrasound-triggered release of recombinant tissue-type plasminogen activator from echogenic liposomes Ultrasound Med Biol, 36 1 , 145-57Smith, Denise A B; Vaidya, Sampada S; Kopechek, Jonathan A; Huang, Shao-Ling; Klegerman, Melvin E; McPherson, David D; Holland, Christy K 2010. Ultrasound-triggered release of recombinant tissue-type plasminogen activator from echogenic liposomes. Ultrasound in medicine & biology, 36 1, 145-57Holland, C. K.; McPherson, D. D. 2009. Echogenic Lipsomes for Targeted Drug Delivery Proc IEEE Int Symp Biomed Imaging, 2009 3 , 755-758Holland, Christy K; McPherson, David D 2009. ECHOGENIC LIPSOMES FOR TARGETED DRUG DELIVERY. Proceedings / IEEE International Symposium on Biomedical Imaging: from nano to macro. IEEE International Symposium on Biomedical Imaging, 2009 , 755-758Meunier, J. M.; Holland, C. K.; Pancioli, A. M.; Lindsell, C. J.; Shaw, G. J. 2009. Effect of low frequency ultrasound on combined rt-PA and eptifibatide thrombolysis in human clots Thromb Res, 123 3 , 528-36Meunier, Jason M; Holland, Christy K; Pancioli, Arthur M; Lindsell, Christopher J; Shaw, George J 2009. Effect of low frequency ultrasound on combined rt-PA and eptifibatide thrombolysis in human clots. Thrombosis research, 123 3, 528-36Salgaonkar, V. A.; Datta, S.; Holland, C. K.; Mast, T. D. 2009. Passive cavitation imaging with ultrasound arrays J Acoust Soc Am, 126 6 , 3071-83Salgaonkar, Vasant A; Datta, Saurabh; Holland, Christy K; Mast, T Douglas 2009. Passive cavitation imaging with ultrasound arrays. The Journal of the Acoustical Society of America, 126 6, 3071-83Shaw, G. J.; Meunier, J. M.; Huang, S. L.; Lindsell, C. J.; McPherson, D. D.; Holland, C. K. 2009. Ultrasound-enhanced thrombolysis with tPA-loaded echogenic liposomes Thromb Res, 124 3 , 306-10Shaw, George J; Meunier, Jason M; Huang, Shao-Ling; Lindsell, Christopher J; McPherson, David D; Holland, Christy K 2009. Ultrasound-enhanced thrombolysis with tPA-loaded echogenic liposomes. Thrombosis research, 124 3, 306-10Ammi, A. Y.; Mast, T. D.; Huang, I. H.; Abruzzo, T. A.; Coussios, C. C.; Shaw, G. J.; Holland, C. K. 2008. Characterization of ultrasound propagation through ex-vivo human temporal bone Ultrasound Med Biol, 34 10 , 1578-89Ammi, Azzdine Y; Mast, T Douglas; Huang, I-Hua; Abruzzo, Todd A; Coussios, Constantin-C; Shaw, George J; Holland, Christy K 2008. Characterization of ultrasound propagation through ex-vivo human temporal bone. Ultrasound in medicine & biology, 34 10, 1578-89Datta, S.; Coussios, C. C.; Ammi, A. Y.; Mast, T. D.; de Courten-Myers, G. M.; Holland, C. K. 2008. Ultrasound-enhanced thrombolysis using Definity as a cavitation nucleation agent Ultrasound Med Biol, 34 9 , 1421-33Datta, Saurabh; Coussios, Constantin-C; Ammi, Azzdine Y; Mast, T Douglas; de Courten-Myers, Gabrielle M; Holland, Christy K 2008. Ultrasound-enhanced thrombolysis using Definity as a cavitation nucleation agent. Ultrasound in medicine & biology, 34 9, 1421-33Holland, C. K.; Vaidya, S. S.; Datta, S.; Coussios, C. C.; Shaw, G. J. 2008. Ultrasound-enhanced tissue plasminogen activator thrombolysis in an in vitro porcine clot model Thromb Res, 121 5 , 663-73Holland, Christy K; Vaidya, Sampada S; Datta, Saurabh; Coussios, Constantin-C; Shaw, George J 2008. Ultrasound-enhanced tissue plasminogen activator thrombolysis in an in vitro porcine clot model. Thrombosis research, 121 5, 663-73Kee, P. H.; Abruzzo, T. A.; Smith, D. A.; Kopechek, J. A.; Wang, B.; Huang, S. L.; MacDonald, R. C.; Holland, C. K.; McPherson, D. D. 2008. Synthesis, acoustic stability, and pharmacologic activities of papaverine-loaded echogenic liposomes for ultrasound controlled drug delivery J Liposome Res, 18 4 , 263-77Kopechek, J. A.; Abruzzo, T. M.; Wang, B.; Chrzanowski, S. M.; Smith, D. A.; Kee, P. H.; Huang, S.; Collier, J. H.; McPherson, D. D.; Holland, C. K. 2008. Ultrasound-mediated release of hydrophilic and lipophilic agents from echogenic liposomes J Ultrasound Med, 27 11 , 1597-606Kopechek, Jonathan A; Abruzzo, Todd M; Wang, Boyu; Chrzanowski, Stephen M; Smith, Denise A B; Kee, Patrick H; Huang, Shaoling; Collier, Joel H; McPherson, David D; Holland, Christy K 2008. Ultrasound-mediated release of hydrophilic and lipophilic agents from echogenic liposomes. Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 27 11, 1597-606Mast, T Douglas; Salgaonkar, Vasant A; Karunakaran, Chandrapriya; Besse, John A; Datta, Saurabh; Holland, Christy K 2008. Acoustic emissions during 3.1 MHz ultrasound bulk ablation in vitro. Ultrasound in medicine & biology, 34 9, 1434-48Mast, T. D.; Salgaonkar, V. A.; Karunakaran, C.; Besse, J. A.; Datta, S.; Holland, C. K. 2008. Acoustic emissions during 3.1 MHz ultrasound bulk ablation in vitro Ultrasound Med Biol, 34 9 , 1434-48Miller, D. L.; Averkiou, M. A.; Brayman, A. A.; Everbach, E. C.; Holland, C. K.; Wible, J. H., Jr.; Wu, J. 2008. Bioeffects considerations for diagnostic ultrasound contrast agents J Ultrasound Med, 27 4 , 611-32; quiz 633-6Shaw, G. J.; Meunier, J. M.; Lindsell, C. J.; Holland, C. K. 2008. Tissue plasminogen activator concentration dependence of 120 kHz ultrasound-enhanced thrombolysis Ultrasound Med Biol, 34 11 , 1783-92Shaw, George J; Meunier, Jason M; Lindsell, Christopher J; Holland, Christy K 2008. Tissue plasminogen activator concentration dependence of 120 kHz ultrasound-enhanced thrombolysis. Ultrasound in medicine & biology, 34 11, 1783-92Wang, Y.; Krishnamoorthy, M.; Banerjee, R.; Zhang, J.; Rudich, S.; Holland, C.; Arend, L.; Roy-Chaudhury, P. 2008. Venous stenosis in a pig arteriovenous fistula model--anatomy, mechanisms and cellular phenotypes Nephrol Dial Transplant, 23 2 , 525-33Wang, Yang; Krishnamoorthy, Mahesh; Banerjee, Rupak; Zhang, Jianhua; Rudich, Steven; Holland, Christy; Arend, Lois; Roy-Chaudhury, Prabir 2008. Venous stenosis in a pig arteriovenous fistula model--anatomy, mechanisms and cellular phenotypes. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 23 2, 525-33Zhou, X.; Espy-Wilson, C. Y.; Boyce, S.; Tiede, M.; Holland, C.; Choe, A. 2008. A magnetic resonance imaging-based articulatory and acoustic study of "retroflex" and "bunched" American English /r J Acoust Soc Am, 123 6 , 4466-81Meunier, J. M.; Holland, C. K.; Lindsell, C. J.; Shaw, G. J. 2007. Duty cycle dependence of ultrasound enhanced thrombolysis in a human clot model Ultrasound Med Biol, 33 4 , 576-83Meunier, Jason M; Holland, Christy K; Lindsell, Christopher J; Shaw, George J 2007. Duty cycle dependence of ultrasound enhanced thrombolysis in a human clot model. Ultrasound in medicine & biology, 33 4, 576-83Nahirnyak, V.; Mast, T. D.; Holland, C. K. 2007. Ultrasound-induced thermal elevation in clotted blood and cranial bone Ultrasound Med Biol, 33 8 , 1285-95Nahirnyak, Volodymyr; Mast, T Douglas; Holland, Christy K 2007. Ultrasound-induced thermal elevation in clotted blood and cranial bone. Ultrasound in medicine & biology, 33 8, 1285-95Shaw, G. J.; Dhamija, A.; Bavani, N.; Wagner, K. R.; Holland, C. K. 2007. Arrhenius temperature dependence of in vitro tissue plasminogen activator thrombolysis Phys Med Biol, 52 11 , 2953-67Shaw, George J; Dhamija, Ashima; Bavani, Nazli; Wagner, Kenneth R; Holland, Christy K 2007. Arrhenius temperature dependence of in vitro tissue plasminogen activator thrombolysis. Physics in medicine and biology, 52 11, 2953-67Smith, D. A.; Porter, T. M.; Martinez, J.; Huang, S.; MacDonald, R. C.; McPherson, D. D.; Holland, C. K. 2007. Destruction thresholds of echogenic liposomes with clinical diagnostic ultrasound Ultrasound Med Biol, 33 5 , 797-809Smith, Denise A B; Porter, Tyrone M; Martinez, Janet; Huang, Shaoling; MacDonald, Robert C; McPherson, David D; Holland, Christy K 2007. Destruction thresholds of echogenic liposomes with clinical diagnostic ultrasound. Ultrasound in medicine & biology, 33 5, 797-809Tiukinhoy-Laing, S. D.; Huang, S.; Klegerman, M.; Holland, C. K.; McPherson, D. D. 2007. Ultrasound-facilitated thrombolysis using tissue-plasminogen activator-loaded echogenic liposomes Thromb Res, 119 6 , 777-84Datta, S.; Coussios, C. C.; McAdory, L. E.; Tan, J.; Porter, T.; De Courten-Myers, G.; Holland, C. K. 2006. Correlation of cavitation with ultrasound enhancement of thrombolysis Ultrasound Med Biol, 32 8 , 1257-67Datta, Saurabh; Coussios, Constantin-C; McAdory, Louis E; Tan, Jun; Porter, Tyrone; De Courten-Myers, Gabrielle; Holland, Christy K 2006. Correlation of cavitation with ultrasound enhancement of thrombolysis. Ultrasound in medicine & biology, 32 8, 1257-67More, S. R.; Lim, T. C.; Li, M.; Holland, C. K.; Boyce, S. E.; Lee, J. H. 2006. Acoustic noise characteristics of a 4 Telsa MRI scanner J Magn Reson Imaging, 23 3 , 388-97More, Shashikant R; Lim, Teik C; Li, Mingfeng; Holland, Christy K; Boyce, Suzanne E; Lee, Jing-Huei 2006. Acoustic noise characteristics of a 4 Telsa MRI scanner. Journal of magnetic resonance imaging : JMRI, 23 3, 388-97Nahirnyak, V. M.; Yoon, S. W.; Holland, C. K. 2006. Acousto-mechanical and thermal properties of clotted blood J Acoust Soc Am, 119 6 , 3766-72Nahirnyak, Volodymyr M; Yoon, Suk Wang; Holland, Christy K 2006. Acousto-mechanical and thermal properties of clotted blood. The Journal of the Acoustical Society of America, 119 6, 3766-72Porter, T. M.; Smith, D. A.; Holland, C. K. 2006. Acoustic techniques for assessing the Optison destruction threshold J Ultrasound Med, 25 12 , 1519-29Porter, Tyrone M; Smith, Denise A B; Holland, Christy K 2006. Acoustic techniques for assessing the Optison destruction threshold. Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 25 12, 1519-29Wright, S. W.; Lindsell, C. J.; Hinckley, W. R.; Williams, A.; Holland, C.; Lewis, C. H.; Heimburger, G. 2006. High fidelity medical simulation in the difficult environment of a helicopter: feasibility, self-efficacy and cost BMC Med Educ, 6 4 , 49Wright, Stewart W; Lindsell, Christopher J; Hinckley, William R; Williams, Annette; Holland, Carolyn; Lewis, Christopher H; Heimburger, Gail 2006. High fidelity medical simulation in the difficult environment of a helicopter: feasibility, self-efficacy and cost. BMC medical education, 6 , 49Cheng, J. Y.; Shaw, G. J.; Holland, C. K. 2005. In vitro microscopic imaging of enhanced thrombolysis with 120-kHz ultrasound in a human clot model Acoust Res Lett Online, 6 1 , 25-29Cheng, Jason Y; Shaw, George J; Holland, Christy K 2005. In vitro microscopic imaging of enhanced thrombolysis with 120-kHz ultrasound in a human clot model. Acoustics research letters online : ARLO, 6 1, 25-29Coussios, C. C.; Holland, C. K.; Jakubowska, L.; Huang, S. L.; MacDonald, R. C.; Nagaraj, A.; McPherson, D. D. 2004. In vitro characterization of liposomes and Optison by acoustic scattering at 3.5 MHz Ultrasound Med Biol, 30 2 , 181-90Coussios, Constantin-C; Holland, Christy K; Jakubowska, Ludwika; Huang, Shao-Ling; MacDonald, Robert C; Nagaraj, Ashwin; McPherson, David D 2004. In vitro characterization of liposomes and Optison by acoustic scattering at 3.5 MHz. Ultrasound in medicine & biology, 30 2, 181-90McPherson, D. D.; Holland, C. K. 2003. Seizing the science of ultrasound: beyond imaging and into physiology and therapeutics J Am Coll Cardiol, 41 9 , 1628-30Taylor, C. R.; Holland, C. K. 2003. Kenneth J. Taylor, MD, PhD, FACP, 1939-2003, pioneer of diagnostic ultrasound imaging J Ultrasound Med, 22 6 , 663-4Fowlkes, J. B.; Holland, C. K. 2000. Mechanical bioeffects from diagnostic ultrasound: AIUM consensus statements. American Institute of Ultrasound in Medicine J Ultrasound Med, 19 2 , 69-72Ouanounou, S.; Tomsick, T. A.; Heitsman, C.; Holland, C. K. 1999. Cavernous sinus and inferior petrosal sinus flow signal on three-dimensional time-of-flight MR angiography AJNR Am J Neuroradiol, 20 8 , 1476-81Ouanounou, S; Tomsick, T A; Heitsman, C; Holland, C K 1999. Cavernous sinus and inferior petrosal sinus flow signal on three-dimensional time-of-flight MR angiography. AJNR. American journal of neuroradiology, 20 8, 1476-81Holland, C K; Brown, J M; Scoutt, L M; Taylor, K J 1998. Lower extremity volumetric arterial blood flow in normal subjects. Ultrasound in medicine & biology, 24 8, 1079-86Holland, C. K.; Brown, J. M.; Scoutt, L. M.; Taylor, K. J. 1998. Lower extremity volumetric arterial blood flow in normal subjects Ultrasound Med Biol, 24 8 , 1079-86Deng, C. X.; Xu, Q.; Apfel, R. E.; Holland, C. K. 1996. In vitro measurements of inertial cavitation thresholds in human blood Ultrasound Med Biol, 22 7 , 939-48Deng, C. X.; Xu, Q.; Apfel, R. E.; Holland, C. K. 1996. Inertial cavitation produced by pulsed ultrasound in controlled host media J Acoust Soc Am, 100 2 Pt 1 , 1199-208Holland, C K; Clancy, M J; Taylor, K J; Alderman, J L; Purushothaman, K; McCauley, T R 1996. Volumetric flow estimation in vivo and in vitro using pulsed-Doppler ultrasound. Ultrasound in medicine & biology, 22 5, 591-603Holland, C K; Deng, C X; Apfel, R E; Alderman, J L; Fernandez, L A; Taylor, K J 1996. Direct evidence of cavitation in vivo from diagnostic ultrasound. Ultrasound in medicine & biology, 22 7, 917-25Holland, C. K.; Clancy, M. J.; Taylor, K. J.; Alderman, J. L.; Purushothaman, K.; McCauley, T. R. 1996. Volumetric flow estimation in vivo and in vitro using pulsed-Doppler ultrasound Ultrasound Med Biol, 22 5 , 591-603Holland, C. K.; Deng, C. X.; Apfel, R. E.; Alderman, J. L.; Fernandez, L. A.; Taylor, K. J. 1996. Direct evidence of cavitation in vivo from diagnostic ultrasound Ultrasound Med Biol, 22 7 , 917-25Brown, J. M.; Hammers, L. W.; Barton, J. W.; Holland, C. K.; Scoutt, L. M.; Pellerito, J. S.; Taylor, K. J. 1995. Quantitative Doppler assessment of acute scrotal inflammation Radiology, 197 2 , 427-31McCauley, T. R.; Pena, C. S.; Holland, C. K.; Price, T. B.; Gore, J. C. 1995. Validation of volume flow measurements with cine phase-contrast MR imaging for peripheral arterial waveforms J Magn Reson Imaging, 5 6 , 663-8Reinhold, C.; Hammers, L.; Taylor, C. R.; Quedens-Case, C. L.; Holland, C. K.; Taylor, K. J. 1995. Characterization of focal hepatic lesions with duplex sonography: findings in 198 patients AJR Am J Roentgenol, 164 5 , 1131-5Dillon, E. H.; Case, C. Q.; Ramos, I. M.; Holland, C. K.; Taylor, K. J. 1993. Endovaginal pulsed and color Doppler in first-trimester pregnancy Ultrasound Med Biol, 19 7 , 517-25Dillon, E. H.; Case, C. Q.; Ramos, I. M.; Holland, C. K.; Taylor, K. J. 1993. Endovaginal US and Doppler findings after first-trimester abortion Radiology, 186 1 , 87-91Holland, C. K. 1993. An ethnographic study of nursing culture as an exploration for determining the existence of a system of ritual J Adv Nurs, 18 9 , 1461-70Holland, C. K.; Taylor, K. J. 1993. Blood flow quantitation: waveform analysis, volume measurement, tumor flow, and the role of color imaging Clin Diagn Ultrasound, 28 2 , 125-39Crum, L. A.; Roy, R. A.; Dinno, M. A.; Church, C. C.; Apfel, R. E.; Holland, C. K.; Madanshetty, S. I. 1992. Acoustic cavitation produced by microsecond pulses of ultrasound: a discussion of some selected results J Acoust Soc Am, 91 2 , 1113-9Holland, C. K.; Roy, R. A.; Apfel, R. E.; Crum, L. A. 1992. In vitro detection of cavitation induced by a diagnostic ultrasound system IEEE Trans Ultrason Ferroelectr Freq Control, 39 1 , 95-101Apfel, R. E.; Holland, C. K. 1991. Gauging the likelihood of cavitation from short-pulse, low-duty cycle diagnostic ultrasound Ultrasound Med Biol, 17 2 , 179-85Holland, C. K.; Apfel, R. E. 1990. Thresholds for transient cavitation produced by pulsed ultrasound in a controlled nuclei environment J Acoust Soc Am, 88 5 , 2059-69Holland, C. K.; Apfel, R. E. 1989. An improved theory for the prediction of microcavitation thresholds IEEE Trans Ultrason Ferroelectr Freq Control, 36 2 , 204-8Atchley, A. A.; Frizzell, L. A.; Apfel, R. E.; Holland, C. K.; Madanshetty, S.; Roy, R. A. 1988. Thresholds for cavitation produced in water by pulsed ultrasound Ultrasonics, 26 5 , 280-5Lattwein K.;Shekhar H.;Van Wamel W.;Gonzalez T.;Herr A.;Holland C.;Kooiman K. 12-01-2018. An in vitro proof-of-principle study of sonobactericide Scientific Reports, 8 1, Krishnamoorthy M.K.;Roy-Chaudhury P.;Wang Y.;Holland C.K.;Rigger D.;Choe A.;Banerjee R.K. 12-01-2009. Vascular remodeling of arteriovenous fistula Proceedings of the ASME Summer Bioengineering Conference 2009, SBC2009, PART B, 1077-1078Kee P.;Abruzzo T.;Smith D.;Kopechek J.;Wang B.;Huang S.;MacDonald R.;Holland C.;McPherson D. 12-01-2008. Synthesis, acoustic stability, and pharmacologic activities of papaverine-loaded echogenic liposomes Journal of Liposome Research, 18 4, 263-277Holland C.;McPherson D. 11-17-2009. Echogenic lipsomes for targeted drug delivery Proceedings - 2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2009, , 755-758Haworth K.;Goldstein B.;Mercado-Shekhar K.;Holland C.;Redington A. 10-31-2017. Dissolved oxygen scavenging by acoustic droplet vaporization using intravascular ultrasound IEEE International Ultrasonics Symposium, IUS, , Haworth K.J.;Arunkumar P.;Goldstein B.H.;Su H.;Mercado-Shekhar K.P.;Privitera E.M.;Srivastava R.;Holland C.K.;Redington A.N. 10-31-2017. Dissolved oxygen scavenging by acoustic droplet vaporization using intravascular ultrasound IEEE International Ultrasonics Symposium, IUS, , Bader K.;Holland C. 10-28-2015. Development of a hybrid finite difference solution of the Westervelt equation using the fast nearfie AIP Conference Proceedings, 1685 , Britton G.;Kim H.;Kee P.;Aronowski J.;Holland C.;McPherson D.;Huang S. 10-19-2010. In vivo therapeutic gas delivery for neuroprotection with echogenic liposomes Circulation, 122 16, 1578-1587 Holland C.K.; Shekhar H.; Lafond M. 10-01-2019. Lipid-shelled microbubbles for ultrasound-triggered release of bioactive gases to treat stroke and c IEEE International Ultrasonics Symposium, IUS, 2019-October , 2037-2039Laing S.;Moody M.;Kim H.;Smulevitz B.;Huang S.;Holland C.;McPherson D.;Klegerman M. 10-01-2012. Thrombolytic efficacy of tissue plasminogen activator-loaded echogenic liposomes in a rabbit thrombu Thrombosis Research, 130 4, 629-635Mast T.;Salgaonkar V.;Karunakaran C.;Besse J.;Datta S.;Holland C. 09-24-2007. Measurements of cavitation dose, echogenicity, and temperature during ultrasound ablation AIP Conference Proceedings, 911 , 335-341 Hendley S.A.; Paul J.D.; Maxwell A.D.; Haworth K.J.; Holland C.K.; Bader K.B. 09-01-2021. Clot Degradation Under the Action of Histotripsy Bubble Activity and a Lytic Drug IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 68 9, 2942-2952Salgaonkar V.;Karunakaran C.;Besse J.;Heinlein G.;Datta S.;Holland C.;Mast T. 08-31-2007. Image-guided Ex vivo liver ablation by unfocused ultrasound using passive cavitation detection Progress in Biomedical Optics and Imaging - Proceedings of SPIE, 6440 , Karunakaran C.;Burgess M.;Holland C.;Mast T. 07-21-2009. Role of cavitation in bulk ultrasound ablation: A histologic study AIP Conference Proceedings, 1113 , 43-47Salgaonkar V.;Datta S.;Holland C.;Masta T. 07-21-2009. Passive imaging of cavitational acoustic emissions with ultrasound arrays AIP Conference Proceedings, 1113 , 73-77Cheng J.;Shaw G.;Holland C. 07-01-2005. In vitro microscopic imaging of enhanced thrombolysis with 120-kHz ultrasound in a human clot model Acoustic Research Letters Online, 6 3, 25-29Haworth K.;Salgaonkar V.;Corregan N.;Holland C.;Mast T. 06-19-2013. Spatial specificity and sensitivity of passive cavitation imaging for monitoring high-intensity focu Proceedings of Meetings on Acoustics, 19 , Zhou X.;Espy-Wilson C.Y.;Boyce S.;Tiede M.;Holland C.;Choe A. 06-17-2008. A magnetic resonance imaging-based articulatory and acoustic study of "retroflex" and "bunched" Amer Journal of the Acoustical Society of America, 123 6, 4466-4481 Haworth K.J.; Salido N.G.; Lafond M.; Escudero D.S.; Holland C.K. 06-01-2023. Passive Cavitation Imaging Artifact Reduction Using Data-Adaptive Spatial Filtering IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 70 6, 498-509Laing S.;Moody M.;Smulevitz B.;Kim H.;Kee P.;Huang S.;Holland C.;McPherson D. 06-01-2011. Ultrasound-enhanced thrombolytic effect of tissue plasminogen activator-loaded echogenic liposomes i Arteriosclerosis, Thrombosis, and Vascular Biology, 31 6, 1357-1359Laing S.;Kim H.;Kopechek J.;Parikh D.;Huang S.;Klegerman M.;Holland C.;McPherson D. 06-01-2010. Ultrasound-mediated delivery of echogenic immunoliposomes to porcine vascular smooth muscle cells in Journal of Liposome Research, 20 2, 160-167McPherson D.;Holland C. 05-07-2003. Seizing the science of ultrasound: Beyond imaging and into physiology and therapeutics Journal of the American College of Cardiology, 41 9, 1628-1630Haworth K.;Raymond J.;Radhakrishnan K.;Moody M.;Huang S.;Peng T.;Shekhar H.;Klegerman M.;Kim H.;McPherson D.;Holland C. 05-01-2016. Erratum to: "Trans-stent B-mode Ultrasound and Passive Cavitation Imaging" in Ultrasound Med Biol 20 Ultrasound in Medicine and Biology, 42 5, 1244Holland C. 04-01-2016. ACOUSTICAL NEWS-USA Journal of the Acoustical Society of America, 139 4, Tiukinhoy-Laing S.;Huang S.;Klegerman M.;Holland C.;McPherson D. 03-23-2007. Ultrasound-facilitated thrombolysis using tissue-plasminogen activator-loaded echogenic liposomes Thrombosis Research, 119 6, 777-784Klegerman M.;Wassler M.;Huang S.;Zou Y.;Kim H.;Shelat H.;Holland C.;Geng Y.;McPherson D. 03-19-2010. Liposomal modular complexes for simultaneous targeted delivery of bioactive gases and therapeutics Journal of Controlled Release, 142 3, 326-331Toepfer N.;Racadio J.;Adams J.;Babcock D.;Holland C. 03-01-2006. Aortic pseudothrombus: A sonographic artifact in the abdominal aorta Journal of Diagnostic Medical Sonography, 22 2, 131-134Shekhar H.;Smith N.;Raymond J.;Holland C. 02-01-2018. Effect of Temperature on the Size Distribution, Shell Properties, and Stability of Definity<sup&g Ultrasound in Medicine and Biology, 44 2, 434-446Herbst S.M.;Klegerman M.E.;Kim H.;Qi J.;Shelat H.;Wassler M.;Moody M.R.;Yang C.M.;Ge X.;Zou Y.;Kopechek J.A.;Clubb F.J.;Kraemer D.C.;Huang S.;Holland C.K.;McPherson D.D.;Geng Y.J. 02-01-2010. Delivery of stem cells to porcine arterial wall with echogenic liposomes conjugated to antibodies ag Molecular Pharmaceutics, 7 1, 3-11 Holland C.K. 01-01-2022. Editorial Ultrasound in Medicine and Biology, 48 1, 1-2 Maxwell A.D.; Haworth K.J.; Holland C.K.; Hendley S.A.; Kreider W.; Bader K.B. 01-01-2022. Design and Characterization of an Ultrasound Transducer for Combined Histotripsy-Thrombolytic Therap IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 69 1, 156-165 Kee P.H.; Moody M.R.; Huang S.L.; Kim H.; Yin X.; Peng T.; Laing S.T.; Klegerman M.E.; Rahbar M.H.; Vela D.; Genstler C.; Haworth K.J.; Holland C.K.; McPherson D.D. 01-01-2020. Stabilizing Peri-Stent Restenosis Using a Novel Therapeutic Carrier JACC: Basic to Translational Science, 5 1, 1-11 Lafond M.; Shekhar H.; Panmanee W.; Collins S.D.; Palaniappan A.; McDaniel C.T.; Hassett D.J.; Holland C.K. 01-01-2020. Bactericidal activity of lipid-shelled nitric oxide-loaded microbubbles Frontiers in Pharmacology, 10 , Bader K.;Haworth K.;Maxwell A.;Holland C. 01-01-2018. Post Hoc Analysis of Passive Cavitation Imaging for Classification of Histotripsy-Induced Liquefacti IEEE Transactions on Medical Imaging, 37 1, 106-115Haworth K.;Bader K.;Rich K.;Holland C.;Mast T. 01-01-2017. Quantitative frequency-domain passive cavitation imaging IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 64 1, 177-191Mukherjee P.;Kandadai M.;Shaw G.;Holland C.;Papautsky I. 01-01-2015. Generation of drug loaded echogenic liposomes using microfluidic hydrodynamic focusing MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, , 466-468Ferrara K.;Griffin R.;Guha C.;Holland C.;Lafon C. 01-01-2013. TU?E?144?01: Advanced Novel Technologies & Therapeutic Strategies Medical Physics, 40 6, 451Holland C.;Shaw G.;Datta S. 01-01-2010. Ultrasound-enhanced thrombolysis Therapeutic Ultrasound: Mechanisms to Applications, , 239-260Fowlkes J.B.;Abramowicz J.S.;Church C.C.;Holland C.K.;Miller D.L.;O'Brien W.D.;Sanghvi N.T.;Stratmeyer M.E.;Zachary J.F.;Deng C.X.;Harris G.R.;Herman B.A.;Hynynen K.H.;Merritt C.R.B.;Thomenius K.E.;Bailey M.R.;Carson P.L.;Carstensen E.L.;Frizzell L.A.;Nyborg W.L.;Barnett S.B.;Duck F.A.;Edmonds P.D.;Ziskin M.C.;Abbott J.G.;Dalecki D.;Dunn F.;Greenleaf J.F.;Salvesen K.A.;Siddiqi T.A.;Averkiou M.A.;Brayman A.A.;Everbach E.C.;Wible J.H.;Wu J.;Simpson D.G. 01-01-2008. American Institute of Ultrasound in Medicine consensus report on potential bioeffects of diagnostic Journal of Ultrasound in Medicine, 27 4, 503-515Miller D.L.;Averkiou M.A.;Brayman A.A.;Everbach E.C.;Holland C.K.;Wible J.H.;Wu J. 01-01-2008. Bioeffects considerations for diagnostic ultrasound contrast agents Journal of Ultrasound in Medicine, 27 4, 611-632Holland C. 01-01-2007. Online review facilitates rapid publishing Ultrasound in Medicine and Biology, 33 1, 1-2Cheng J.;Shaw G.;Holland C. 01-01-2005. In vitro microscopic imaging of enhanced thrombolysis with 120-kHz ultrasound in a human clot model Acoustic Research Letters Online, 6 1, 25-29Holland C.;Everbach E. 01-01-2005. Guest editorial: Sono et Gravitas - The legacy of Robert Edmund Apfel Acoustic Research Letters Online, 6 3, Taylor C.;Holland C. 01-01-2003. Kenneth J. Taylor, MD, PhD, FACP, 1939-2003, pioneer of diagnostic ultrasound imaging. Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 22 6, 663-664Fowlkes J.;Holland C. 01-01-2000. Mechanical bioeffects from diagnostic ultrasound: AIUM consensus statements. American Institute of U Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 19 2, 69-72Fowlkes J.;Holland C.;Kremkau F. 01-01-2000. Mechanical bioeffects from diagnostic ultrasound: AIUM consensus statements Journal of Ultrasound in Medicine, 19 2, 68-168Deng C.;Xu Q.;Apfel R.;Holland C. 01-01-1996. Inertial cavitation produced by pulsed ultrasound in controlled host media Journal of the Acoustical Society of America, 100 2 I, 1199-1208Deng C.;Xu Q.;Apfel R.;Holland C. 01-01-1996. In vitro measurements of inertial cavitation thresholds in human blood Ultrasound in Medicine and Biology, 22 7, 939-948Brown J.M.;Hammers L.W.;Barton J.W.;Holland C.K.;Scoutt L.M.;Pellerito J.S.;Taylor K.J.W. 01-01-1995. Quantitative Doppler assessment of acute scrotal inflammation Radiology, 197 2, 427-431McCauley T.R.;Pena C.S.;Holland C.K.;Price T.B.;Gore J.C. 01-01-1995. Validation of volume flow measurements with cine phase?contrast MR imaging for peripheral arterial w Journal of Magnetic Resonance Imaging, 5 6, 663-668Reinhold C.;Hammers L.;Taylor C.;Quedens-Case C.;Holland C.;Taylor K. 01-01-1995. Characterization of focal hepatic lesions with duplex sonography: Findings in 198 patients American Journal of Roentgenology, 164 5, 1131-1135Dillon E.;Case C.;Ramos I.;Holland C.;Taylor K. 01-01-1993. Endovaginal pulsed and color doppler in first-trimester pregnancy Ultrasound in Medicine and Biology, 19 7, 517-525Dillon E.;Case C.;Ramos I.;Holland C.;Taylor K. 01-01-1993. Endovaginal US and Doppler findings after first-trimester abortion Radiology, 186 1, 87-91Holland C.;Taylor K. 01-01-1993. Blood flow quantitation: waveform analysis, volume measurement, tumor flow, and the role of color im Clinics in diagnostic ultrasound, 28 , 125-139Crum L.;Roy R.;Dinno M.;Church C.;Apfel R.;Holland C.;Madanshetty S. 01-01-1992. Acoustic cavitation produced by microsecond pulses of ultrasound: A discussion of some selected resu Journal of the Acoustical Society of America, 91 2, 1113-1119Holland C.;Roy R.;Apfel R.;Crum L. 01-01-1992. In Vitro Detection of Cavitation Induced by a Diagnostic Ultrasound System IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 39 1, 95-101Apfel R.;Holland C. 01-01-1991. Gauging the likelihood of cavitation from short-pulse, low-duty cycle diagnostic ultrasound Ultrasound in Medicine and Biology, 17 2, 179-185Holland C.;Apfel R. 01-01-1990. Thresholds for transient cavitation produced by pulsed ultrasound in a controlled nuclei environment Journal of the Acoustical Society of America, 88 5, 2059-2069Holland C. 01-01-1989. Thresholds of transient cavitation produced by pulsed ultrasound in a controlled nuclei environment Journal of the Acoustical Society of America, 86 2, 844Holland C.;Apfel R. 01-01-1989. An Improved Theory for the Prediction of Microcavitation Thresholds IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 36 2, 204-208Atchley A.;Frizzell L.;Apfel R.;Holland C.;Madanshetty S.;Roy R. 01-01-1988. Thresholds for cavitation produced in water by pulsed ultrasound Ultrasonics, 26 5, 280-285Bhatt, Seema R; Eckerle, Michelle D; Reed, Jennifer L; Robinson, Venita; Brown, Angela; Lippe, Joyce; Holland, Carolyn; Iyer, Srikant . Implementation of Targeted Point of Care HIV Testing in a Pediatric Emergency Department. Pediatric quality & safety, 5 1, e248