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Pathobiology & Molecular Medicine

Photo of  Francis McCormack, MD

Francis McCormack, MD

Professor of Medicine, Department of Internal Medicine, UC College of Medicine<br>Division Director, Pulmonary Critical Care and Sleep Medicine

Education/Credentials
  • Bachelor's Degree (magna cum laude): University of California, San Diego
  • Medical Degree: University of Texas Medical Branch
  • Internship and Residency : University of Michigan
  • Chief Residency : University of Michigan
  • Clinical Fellowship : University of Colorado Health Sciences Center
  • Research Fellowship National : Jewish Center and Medicine University of Colorado Health Sciences Center

Board Certifications & Licenses
  • American Board of Internal Medicine, 1985
  • American Board of Internal Medicine - Pulmonary, 1988
  • American Board of Internal Medicine - Critical Care, 1989
Contact Information
  • Internal Medicine
  • Medical Sciences Building 6165
  • 231 Albert Sabin Way, ML 0564
  • Cincinnati, Ohio 45267
  • Office 513-558-4831
  • Fax 513-558-4858
  • Email frank.mccormack@uc.edu

Peer Reviewed Publications

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Feemster, Laura C; Lyons, Patrick G; Chatterjee, Rohini S; Kidambi, Pranav; McCormack, Francis X; Moss, Joel; Wilson, Kevin C; Thomson, Carey C 2017. Summary for Clinicians: Lymphangioleiomyomatosis Diagnosis and Management Clinical Practice Guideline. Annals of the American Thoracic Society, 14 7, 1073-1075

Gupta, Nishant; Kopras, Elizabeth J; Henske, Elizabeth P; James, Laura E; El-Chemaly, Souheil; Veeraraghavan, Srihari; Drake, Matthew G; McCormack, Francis X 2017. Spontaneous Pneumothoraces in Patients with Birt-Hogg-Dubé Syndrome. Annals of the American Thoracic Society, 14 5, 706-713

Gupta, Nishant; Langenderfer, Dale; McCormack, Francis X; Schauer, Daniel P; Eckman, Mark H 2017. Chest Computed Tomographic Image Screening for Cystic Lung Diseases in Patients with Spontaneous Pneumothorax Is Cost Effective. Annals of the American Thoracic Society, 14 1, 17-25

Han, MeiLan K; Tyburczy, Magdalena E; Darling, Thomas N; Kazerooni, Ella A; Myers, Jeffrey L; McCormack, Francis X; Moss, Joel; Kwiatkowski, David J 2017. Apparent Sporadic Lymphangioleiomyomatosis (LAM) in a Man Due to Extreme Mosaicism for a TSC2 Mutation. Annals of the American Thoracic Society, ,

Kristof, Arnold S; Petrof, Basil J; Hamid, Qutayba; Kolb, Martin; Landry, Jennifer S; MacKenzie, Alex; McCormack, Francis X; Murawski, Inga J; Moss, Joel; Rauch, Frank; Rosas, Ivan O; Shapiro, Adam J; Smith, Benjamin M; Thomas, David Y; Trapnell, Bruce C; Young, Lisa R; Zariwala, Maimoona A 2017. An Official American Thoracic Society Workshop Report: Translational Research in Rare Respiratory Diseases. Annals of the American Thoracic Society, 14 8, 1239-1247

Krymskaya, Vera P; McCormack, Francis X 2017. Lymphangioleiomyomatosis: A Monogenic Model of Malignancy. Annual review of medicine, 68 , 69-83

Lee, Lynn H; Gasilina, Anjelika; Roychoudhury, Jayeeta; Clark, Jason; McCormack, Francis X; Pressey, Joseph; Grimley, Michael S; Lorsbach, Robert; Ali, Siraj; Bailey, Mark; Stephens, Philip; Ross, Jeffrey S; Miller, Vincent A; Nassar, Nicolas N; Kumar, Ashish R 2017. Real-time genomic profiling of histiocytoses identifies early-kinase domain BRAF alterations while improving treatment outcomes. JCI insight, 2 3, e89473

Liu, Huan; Jakubzick, Claudia; Osterburg, Andrew R; Nelson, Rebecca L; Gupta, Nishant; McCormack, Francis X; Borchers, Michael T 2017. Dendritic Cell Trafficking and Function in Rare Lung Diseases. American journal of respiratory cell and molecular biology, ,

Lu, Calvin; Lee, Hye-Seung; Pappas, George P; Dilling, Daniel F; Burger, Charles D; Shifren, Adrian; Veeraraghavan, Srihari; Chapman, Jeffrey T; Parambil, Joseph; Ruoss, Stephen J; Young, Lisa R; Hammes, Stephen R; Kopras, Elizabeth J; Roads, Tammy; Krischer, Jeffrey P; McCormack, Francis X 2017. A Phase II Clinical Trial of an Aromatase Inhibitor for Postmenopausal Women with Lymphangioleiomyomatosis. Annals of the American Thoracic Society, 14 6, 919-928

McCormack, Francis X; Gupta, Nishant; Finlay, Geraldine; Young, Lisa R; Johnson, Simon; Cottin, Vincent; Wilson, Kevin; Moss, Joel 2017. Reply to Official ATS/JRS Clinical Practice Guidelines: Lymphangioleiomyomatosis Diagnosis and Management. American journal of respiratory and critical care medicine, ,

Nikolaidis, Nikolaos M; Noel, John G; Pitstick, Lori B; Gardner, Jason C; Uehara, Yasuaki; Wu, Huixing; Saito, Atsushi; Lewnard, Kara E; Liu, Huan; White, Mitchell R; Hartshorn, Kevan L; McCormack, Francis X 2017. Mitogenic stimulation accelerates influenza-induced mortality by increasing susceptibility of alveolar type II cells to infection. Proceedings of the National Academy of Sciences of the United States of America, 114 32, E6613-E6622

Noel, John G; Ramser, Benjamin J; Cancelas, Jose A; McCormack, Francis X; Gardner, Jason C 2017. Thermal injury of the skin induces G-CSF-dependent attenuation of EPO-mediated STAT signaling and erythroid differentiation arrest in mice. Experimental hematology, ,

Rynkiewicz, Michael J; Wu, Huixing; Cafarella, Tanya R; Nikolaidis, Nikolaos M; Head, James F; Seaton, Barbara A; McCormack, Francis X 2017. Differential Ligand Binding Specificities of the Pulmonary Collectins Are Determined by the Conformational Freedom of a Surface Loop. Biochemistry, 56 31, 4095-4105

Sontake, Vishwaraj; Wang, Yunguan; Kasam, Rajesh K; Sinner, Debora; Reddy, Geereddy B; Naren, Anjaparavanda P; McCormack, Francis X; White, Eric S; Jegga, Anil G; Madala, Satish K 2017. Hsp90 regulation of fibroblast activation in pulmonary fibrosis. JCI insight, 2 4, e91454

Argula, Rahul G; Kokosi, Maria; Lo, Pechin; Kim, Hyun J; Ravenel, James G; Meyer, Cristopher; Goldin, Jonathan; Lee, Hye-Seung; Strange, Charlie; McCormack, Francis X 2016. A Novel Quantitative Computed Tomographic Analysis Suggests How Sirolimus Stabilizes Progressive Air Trapping in Lymphangioleiomyomatosis. Annals of the American Thoracic Society, 13 3, 342-9

Gardner, Jason C; Wu, Huixing; Noel, John G; Ramser, Benjamin J; Pitstick, Lori; Saito, Atsushi; Nikolaidis, Nikolaos M; McCormack, Francis X 2016. Keratinocyte growth factor supports pulmonary innate immune defense through maintenance of alveolar antimicrobial protein levels and macrophage function. American journal of physiology. Lung cellular and molecular physiology, 310 9, L868-79

Goh, Boon Chong; Wu, Huixing; Rynkiewicz, Michael J; Schulten, Klaus; Seaton, Barbara A; McCormack, Francis X 2016. Elucidation of Lipid Binding Sites on Lung Surfactant Protein A Using X-ray Crystallography, Mutagenesis, and Molecular Dynamics Simulations. Biochemistry, 55 26, 3692-701

Gupta, Nishant; Wikenheiser-Brokamp, Kathryn A; Fischer, Aryeh; McCormack, Francis X 2016. Diffuse Cystic Lung Disease as the Presenting Manifestation of Sjögren Syndrome. Annals of the American Thoracic Society, 13 3, 371-5

Itkin, Maxim G; McCormack, Francis X; Dori, Yoav 2016. Diagnosis and Treatment of Lymphatic Plastic Bronchitis in Adults Using Advanced Lymphatic Imaging and Percutaneous Embolization. Annals of the American Thoracic Society, 13 10, 1689-1696

Itkin, Maxim; McCormack, Francis X 2016. Nonmalignant Adult Thoracic Lymphatic Disorders. Clinics in chest medicine, 37 3, 409-20

Kotloff, Robert M; McCormack, Francis X 2016. Rare Lung Diseases: Occasionally the "Horse" Has Stripes. Clinics in chest medicine, 37 3, xv-xvi

McCormack, Francis X; Gupta, Nishant; Finlay, Geraldine R; Young, Lisa R; Taveira-DaSilva, Angelo M; Glasgow, Connie G; Steagall, Wendy K; Johnson, Simon R; Sahn, Steven A; Ryu, Jay H; Strange, Charlie; Seyama, Kuniaki; Sullivan, Eugene J; Kotloff, Robert M; Downey, Gregory P; Chapman, Jeffrey T; Han, MeiLan K; D'Armiento, Jeanine M; Inoue, Yoshikazu; Henske, Elizabeth P; Bissler, John J; Colby, Thomas V; Kinder, Brent W; Wikenheiser-Brokamp, Kathryn A; Brown, Kevin K; Cordier, Jean F; Meyer, Cristopher; Cottin, Vincent; Brozek, Jan L; Smith, Karen; Wilson, Kevin C; Moss, Joel 2016. Official American Thoracic Society/Japanese Respiratory Society Clinical Practice Guidelines: Lymphangioleiomyomatosis Diagnosis and Management. American journal of respiratory and critical care medicine, 194 6, 748-61

Osterburg, Andrew R; Nelson, Rebecca L; Yaniv, Benyamin Z; Foot, Rachel; Donica, Walter R F; Nashu, Madison A; Liu, Huan; Wikenheiser-Brokamp, Kathryn A; Moss, Joel; Gupta, Nishant; McCormack, Francis X; Borchers, Michael T 2016. NK cell activating receptor ligand expression in lymphangioleiomyomatosis is associated with lung function decline. JCI insight, 1 16, e87270

Saito, Atsushi; McCormack, Francis X 2016. Pulmonary Alveolar Microlithiasis. Clinics in chest medicine, 37 3, 441-8

Soleimani, Manoocher; Barone, Sharon; Xu, Jie; Alshahrani, Saeed; Brooks, Marybeth; McCormack, Francis X; Smith, Roger D; Zahedi, Kamyar 2016. Prostaglandin-E2 Mediated Increase in Calcium and Phosphate Excretion in a Mouse Model of Distal Nephron Salt Wasting. PloS one, 11 7, e0159804

Takada, Toshinori; Mikami, Ayako; Kitamura, Nobutaka; Seyama, Kuniaki; Inoue, Yoshikazu; Nagai, Katsura; Suzuki, Masaru; Moriyama, Hiroshi; Akasaka, Keiichi; Tazawa, Ryushi; Hirai, Toyohiro; Mishima, Michiaki; Hayashida, Mie; Hirose, Masaki; Sugimoto, Chikatoshi; Arai, Toru; Hattori, Noboru; Watanabe, Kentaro; Tamada, Tsutomu; Yoshizawa, Hirohisa; Akazawa, Kohei; Tanaka, Takahiro; Yagi, Keita; Young, Lisa R; McCormack, Francis X; Nakata, Koh 2016. Efficacy and Safety of Long-term Sirolimus Therapy for Asian Patients with Lymphangioleiomyomatosis. Annals of the American Thoracic Society, ,

Goldberg, Hilary J; Harari, Sergio; Cottin, Vincent; Rosas, Ivan O; Peters, Elizabeth; Biswal, Shibadas; Cheng, Yi; Khindri, Sanjeev; Kovarik, John M; Ma, Shenglin; McCormack, Francis X; Henske, Elizabeth Petri 2015. Everolimus for the treatment of lymphangioleiomyomatosis: a phase II study. The European respiratory journal, 46 3, 783-94

Gupta, Nishant; Han, MeiLan K; McCormack, Francis X 2015. Regional Sparing in an Oligemic Lung Segment Supports Hematogenous Spread as a Pathogenic Mechanism in Lymphangioleiomyomatosis. Annals of the American Thoracic Society, 12 8, 1247-8

Gupta, Nishant; Meraj, Riffat; Tanase, Daniel; James, Laura E; Seyama, Kuniaki; Lynch, David A; Akira, Masanori; Meyer, Cristopher A; Ruoss, Stephen J; Burger, Charles D; Young, Lisa R; Almoosa, Khalid F; Veeraraghavan, Srihari; Barker, Alan F; Lee, Augustine S; Dilling, Daniel F; Inoue, Yoshikazu; Cudzilo, Corey J; Zafar, Muhammad A; McCormack, Francis X 2015. Accuracy of chest high-resolution computed tomography in diagnosing diffuse cystic lung diseases. The European respiratory journal, 46 4, 1196-9

Gupta, Nishant; Vassallo, Robert; Wikenheiser-Brokamp, Kathryn A; McCormack, Francis X 2015. Diffuse Cystic Lung Disease. Part II. American journal of respiratory and critical care medicine, 192 1, 17-29

Gupta, Nishant; Vassallo, Robert; Wikenheiser-Brokamp, Kathryn A; McCormack, Francis X 2015. Diffuse Cystic Lung Disease. Part I. American journal of respiratory and critical care medicine, 191 12, 1354-66

Gupta, Rajeev; McCormack, Francis X 2015. Response. Lymphology, 48 1, 52

Mulhall, Aaron M; McCormack, Francis X 2015. A 25-year-old man with fatigue, dyspnea, and pulmonary cysts. Annals of the American Thoracic Society, 12 1, 120-3

Pasula, Rajamouli; Azad, Abul K; Gardner, Jason C; Schlesinger, Larry S; McCormack, Francis X 2015. Keratinocyte growth factor administration attenuates murine pulmonary mycobacterium tuberculosis infection through granulocyte-macrophage colony-stimulating factor (GM-CSF)-dependent macrophage activation and phagolysosome fusion. The Journal of biological chemistry, 290 11, 7151-9

Quintanilla, Hector D; Liu, Yuying; Fatheree, Nicole Y; Atkins, Constance L; Hashmi, Syed S; Floros, Joanna; McCormack, Francis X; Rhoads, Jon Marc; Alcorn, Joseph L 2015. Oral administration of surfactant protein-a reduces pathology in an experimental model of necrotizing enterocolitis. Journal of pediatric gastroenterology and nutrition, 60 5, 613-20

Saito, Atsushi; Nikolaidis, Nikolaos M; Amlal, Hassane; Uehara, Yasuaki; Gardner, Jason C; LaSance, Kathleen; Pitstick, Lori B; Bridges, James P; Wikenheiser-Brokamp, Kathryn A; McGraw, Dennis W; Woods, Jason C; Sabbagh, Yves; Schiavi, Susan C; Altini?ik, Göksel; Jakopovi?, Marko; Inoue, Yoshikazu; McCormack, Francis X 2015. Modeling pulmonary alveolar microlithiasis by epithelial deletion of the Npt2b sodium phosphate cotransporter reveals putative biomarkers and strategies for treatment. Science translational medicine, 7 313, 313ra181

Yang, Linlin; Carrillo, Marykate; Wu, Yuchieh M; DiAngelo, Susan L; Silveyra, Patricia; Umstead, Todd M; Halstead, E Scott; Davies, Michael L; Hu, Sanmei; Floros, Joanna; McCormack, Francis X; Christensen, Neil D; Chroneos, Zissis C 2015. SP-R210 (Myo18A) Isoforms as Intrinsic Modulators of Macrophage Priming and Activation. PloS one, 10 5, e0126576

Cundiff, William B; McCormack, Francis X; Wikenheiser-Brokamp, Kathryn; Starnes, Sandra; Kotloff, Robert; Benzaquen, Sadia 2014. Successful management of a chronic, refractory bronchopleural fistula with endobronchial valves followed by talc pleurodesis. American journal of respiratory and critical care medicine, 189 4, 490-1

Gardner, Jason C; Noel, John G; Nikolaidis, Nikolaos M; Karns, Rebekah; Aronow, Bruce J; Ogle, Cora K; McCormack, Francis X 2014. G-CSF drives a posttraumatic immune program that protects the host from infection. Journal of immunology (Baltimore, Md. : 1950), 192 5, 2405-17

Gupta, R; Kitaichi, M; Inoue, Y; Kotloff, R; McCormack, F X 2014. Lymphatic manifestations of lymphangioleiomyomatosis. Lymphology, 47 3, 106-17

Gupta, R; Kitaichi, M; Inoue, Y; Kotloff, R; McCormack, F X 2014. Lymphatic manifestations of lymphangioleiomyomatosis. Lymphology, 47 3, 106-17

McCormack, Francis X 2014. Chronic sirolimus therapy for lymphangioleiomyomatosis. American journal of respiratory and critical care medicine, 190 12, 1332-3

Nikolaidis, Nikolaos M; White, Mitchell R; Allen, Kimberly; Tripathi, Shweta; Qi, Li; McDonald, Barbara; Taubenberger, Jeffery; Seaton, Barbara A; McCormack, Francis X; Crouch, Erika C; Hartshorn, Kevan L 2014. Mutations flanking the carbohydrate binding site of surfactant protein D confer antiviral activity for pandemic influenza A viruses. American journal of physiology. Lung cellular and molecular physiology, 306 11, L1036-44

Safi, Fadi; Gupta, Anita; Adams, Denise; Anandan, Vasuki; McCormack, Francis X; Assaly, Ragheb 2014. Kaposiform lymphangiomatosis, a newly characterized vascular anomaly presenting with hemoptysis in an adult woman. Annals of the American Thoracic Society, 11 1, 92-5

Cudzilo, Corey J; Szczesniak, Rhonda D; Brody, Alan S; Rattan, Mantosh S; Krueger, Darcy A; Bissler, John J; Franz, David N; McCormack, Francis X; Young, Lisa R 2013. Lymphangioleiomyomatosis screening in women with tuberous sclerosis. Chest, 144 2, 578-85

Czyzyk-Krzeska, Maria F; McCormack, Francis X 2013. Birt-Hogg-Dubé syndrome. Familial cancer, 12 3, 355-6

Gupta, Nishant; McCormack, Francis X 2013. Pulmonary alveolar microlithiasis. American journal of respiratory and critical care medicine, 188 7, e11-2

Gupta, Nishant; Seyama, Kuniaki; McCormack, Francis X 2013. Pulmonary manifestations of Birt-Hogg-Dubé syndrome. Familial cancer, 12 3, 387-96

Krueger, Darcy A; Northrup, Hope 2013. Tuberous sclerosis complex surveillance and management: recommendations of the 2012 International Tuberous Sclerosis Complex Consensus Conference. Pediatric neurology, 49 4, 255-65

McCormack, Francis X; Travis, William D; Colby, Thomas V; Henske, Elizabeth P; Moss, Joel 2013. Reply: Characterization of lymphangioleiomyomatosis as a neoplastic disease. American journal of respiratory and critical care medicine, 188 3, 398-9

McCormack, Francis X; Wilmott, Clay; Young, Lisa R; Wikenheiser-Brokamp, Kathryn 2013. An atoll variant that mocks. American journal of respiratory and critical care medicine, 188 1, 110

Northrup, Hope; Krueger, Darcy A 2013. Tuberous sclerosis complex diagnostic criteria update: recommendations of the 2012 Iinternational Tuberous Sclerosis Complex Consensus Conference. Pediatric neurology, 49 4, 243-54

Oprescu, N; McCormack, F X; Byrnes, S; Kinder, B W 2013. Clinical predictors of mortality and cause of death in lymphangioleiomyomatosis: a population-based registry. Lung, 191 1, 35-42

Safi, Fadi; Gupta, Anita; Adams, Denise; Anandan, Vasuki; McCormack, Francis X; Assaly, Ragheb 2013. Kaposiform Lymphangiomatosis, a Newly Characterized Vascular Anomaly Presenting with Hemoptysis in an Adult Woman. Annals of the American Thoracic Society, ,

Swigris, Jeffrey J; Lee, Hye-Seung; Cohen, Marsha; Inoue, Yoshikazu; Moss, Joel; Singer, Lianne G; Young, Lisa R; McCormack, Francis X 2013. St. George's Respiratory Questionnaire has longitudinal construct validity in lymphangioleiomyomatosis. Chest, 143 6, 1671-8

Young, Lisa R; Lee, Hye-Seung; Inoue, Yoshikazu; Moss, Joel; Singer, Lianne G; Strange, Charlie; Nakata, Koh; Barker, Alan F; Chapman, Jeffrey T; Brantly, Mark L; Stocks, James M; Brown, Kevin K; Lynch, Joseph P; Goldberg, Hilary J; Downey, Gregory P; Swigris, Jeffrey J; Taveira-Dasilva, Angelo M; Krischer, Jeffrey P; Trapnell, Bruce C; McCormack, Francis X 2013. Serum VEGF-D concentration as a biomarker of lymphangioleiomyomatosis severity and treatment response: a prospective analysis of the Multicenter International Lymphangioleiomyomatosis Efficacy of Sirolimus (MILES) trial. The lancet. Respiratory medicine, 1 6, 445-452

Zafar, Muhammad A; McCormack, Francis X; Rahman, Shahid; Tencza, Christian; Wikenheiser-Brokamp, Kathryn A; Young, Lisa R; Shizukuda, Yukitaka; Elwing, Jean M 2013. Pulmonary vascular shunts in exercise-intolerant patients with lymphangioleiomyomatosis. American journal of respiratory and critical care medicine, 188 9, 1167-70

Henske, Elizabeth P; McCormack, Francis X 2012. Lymphangioleiomyomatosis - a wolf in sheep's clothing. The Journal of clinical investigation, 122 11, 3807-16

McCormack, Francis X; Travis, William D; Colby, Thomas V; Henske, Elizabeth P; Moss, Joel 2012. Lymphangioleiomyomatosis: calling it what it is: a low-grade, destructive, metastasizing neoplasm. American journal of respiratory and critical care medicine, 186 12, 1210-2

Meraj, Riffat; Wikenheiser-Brokamp, Kathryn A; Young, Lisa R; Byrnes, Sue; McCormack, Francis X 2012. Utility of transbronchial biopsy in the diagnosis of lymphangioleiomyomatosis. Frontiers of medicine, 6 4, 395-405

Meraj, Riffat; Wikenheiser-Brokamp, Kathryn A; Young, Lisa R; McCormack, Francis X 2012. Lymphangioleiomyomatosis: new concepts in pathogenesis, diagnosis, and treatment. Seminars in respiratory and critical care medicine, 33 5, 486-97

Young, Lisa R; Gulleman, Peter M; Bridges, James P; Weaver, Timothy E; Deutsch, Gail H; Blackwell, Timothy S; McCormack, Francis X 2012. The alveolar epithelium determines susceptibility to lung fibrosis in Hermansky-Pudlak syndrome. American journal of respiratory and critical care medicine, 186 10, 1014-24

Crouch, Erika; Nikolaidis, Nikolaos; McCormack, Francis X; McDonald, Barbara; Allen, Kimberly; Rynkiewicz, Michael J; Cafarella, Tanya M; White, Mitchell; Lewnard, Kara; Leymarie, Nancy; Zaia, Joseph; Seaton, Barbara A; Hartshorn, Kevan L 2011. Mutagenesis of surfactant protein D informed by evolution and x-ray crystallography enhances defenses against influenza A virus in vivo. The Journal of biological chemistry, 286 47, 40681-92

Hagaman, Jared T; Panos, Ralph J; McCormack, Francis X; Thakar, Charuhas V; Wikenheiser-Brokamp, Kathryn A; Shipley, Ralph T; Kinder, Brent W 2011. Vitamin D deficiency and reduced lung function in connective tissue-associated interstitial lung diseases. Chest, 139 2, 353-60

McCormack, Francis X; Inoue, Yoshikazu; Moss, Joel; Singer, Lianne G; Strange, Charlie; Nakata, Koh; Barker, Alan F; Chapman, Jeffrey T; Brantly, Mark L; Stocks, James M; Brown, Kevin K; Lynch, Joseph P; Goldberg, Hilary J; Young, Lisa R; Kinder, Brent W; Downey, Gregory P; Sullivan, Eugene J; Colby, Thomas V; McKay, Roy T; Cohen, Marsha M; Korbee, Leslie; Taveira-DaSilva, Angelo M; Lee, Hye-Seung; Krischer, Jeffrey P; Trapnell, Bruce C 2011. Efficacy and safety of sirolimus in lymphangioleiomyomatosis. The New England journal of medicine, 364 17, 1595-606

Seaman, Danielle M; Meyer, Cristopher A; Gilman, Matthew D; McCormack, Francis X 2011. Diffuse Cystic Lung Disease at High-Resolution CT. AJR. American journal of roentgenology, 196 6, 1305-11

Shang, Feifei; Rynkiewicz, Michael J; McCormack, Francis X; Wu, Huixing; Cafarella, Tanya M; Head, James F; Seaton, Barbara A 2011. Crystallographic complexes of surfactant protein A and carbohydrates reveal ligand-induced conformational change. The Journal of biological chemistry, 286 1, 757-65

Wu, Huixing; Suzuki, Takuji; Carey, Brenna; Trapnell, Bruce C; McCormack, Francis X 2011. Keratinocyte growth factor augments pulmonary innate immunity through epithelium-driven, GM-CSF-dependent paracrine activation of alveolar macrophages. The Journal of biological chemistry, 286 17, 14932-40

Franz, D N; Bissler, J J; McCormack, F X 2010. Tuberous sclerosis complex: neurological, renal and pulmonary manifestations. Neuropediatrics, 41 5, 199-208

Hagaman, Jared T; Ferguson, Bryce; Meyer, Cris; Wang, Jiang; McCormack, Francis X; Nath, Amaresh 2010. Endobronchial Carcinoid Tumor in an HIV-infected Patient. Journal of bronchology & interventional pulmonology, 17 2, 174-6

Hagaman, Jared T; Schauer, Daniel P; McCormack, Francis X; Kinder, Brent W 2010. Screening for lymphangioleiomyomatosis by high-resolution computed tomography in young, nonsmoking women presenting with spontaneous pneumothorax is cost-effective. American journal of respiratory and critical care medicine, 181 12, 1376-82

Johnson, S R; Cordier, J F; Lazor, R; Cottin, V; Costabel, U; Harari, S; Reynaud-Gaubert, M; Boehler, A; Brauner, M; Popper, H; Bonetti, F; Kingswood, C 2010. European Respiratory Society guidelines for the diagnosis and management of lymphangioleiomyomatosis. The European respiratory journal, 35 1, 14-26

Kinder, Brent W; Sherman, A C; Young, L R; Hagaman, J T; Oprescu, N; Byrnes, S; McCormack, Francis X 2010. Predictors for clinical trial participation in the rare lung disease lymphangioleiomyomatosis. Respiratory medicine, 104 4, 578-83

Kinder, Brent; McCormack, Francis X 2010. Clinical trials for rare lung diseases: lessons from lymphangioleiomyomatosis. Lymphatic research and biology, 8 1, 71-9

Seaton, Barbara A; Crouch, Erika C; McCormack, Francis X; Head, James F; Hartshorn, Kevan L; Mendelsohn, Richard 2010. Review: Structural determinants of pattern recognition by lung collectins. Innate immunity, 16 3, 143-50

Young, Lisa R; Vandyke, Rhonda; Gulleman, Peter M; Inoue, Yoshikazu; Brown, Kevin K; Schmidt, Laura S; Linehan, W Marston; Hajjar, Fuad; Kinder, Brent W; Trapnell, Bruce C; Bissler, John J; Franz, David N; McCormack, Francis X 2010. Serum vascular endothelial growth factor-D prospectively distinguishes lymphangioleiomyomatosis from other diseases. Chest, 138 3, 674-81

Gil, Malgorzata; McCormack, Francis X; Levine, Ann Marie 2009. Surfactant protein A modulates cell surface expression of CR3 on alveolar macrophages and enhances CR3-mediated phagocytosis. The Journal of biological chemistry, 284 12, 7495-504

Kinder, Brent W; Brown, Kevin K; McCormack, Francis X; Ix, Joachim H; Kervitsky, Alma; Schwarz, Marvin I; King, Talmadge E 2009. Serum surfactant protein-A is a strong predictor of early mortality in idiopathic pulmonary fibrosis. Chest, 135 6, 1557-63

Schmithorst, Vincent J; Altes, Talissa A; Young, Lisa R; Franz, David N; Bissler, John J; McCormack, Francis X; Dardzinski, Bernard J; Brody, Alan S 2009. Automated algorithm for quantifying the extent of cystic change on volumetric chest CT: initial results in Lymphangioleiomyomatosis. AJR. American journal of roentgenology, 192 4, 1037-44

Young, Lisa R; Franz, David N; Nagarkatte, Preeti; Fletcher, Christopher D M; Wikenheiser-Brokamp, Kathryn A; Galsky, Matthew D; Corbridge, Thomas C; Lam, Anna P; Gelfand, Michael J; McCormack, Francis X 2009. Utility of [18F]2-fluoro-2-deoxyglucose-PET in sporadic and tuberous sclerosis-associated lymphangioleiomyomatosis. Chest, 136 3, 926-33

Ali, Naeem A; O'Brien, James M; Hoffmann, Stephen P; Phillips, Gary; Garland, Allan; Finley, James C W; Almoosa, Khalid; Hejal, Rana; Wolf, Karen M; Lemeshow, Stanley; Connors, Alfred F; Marsh, Clay B 2008. Acquired weakness, handgrip strength, and mortality in critically ill patients. American journal of respiratory and critical care medicine, 178 3, 261-8

Bissler, John J; McCormack, Francis X; Young, Lisa R; Elwing, Jean M; Chuck, Gail; Leonard, Jennifer M; Schmithorst, Vincent J; Laor, Tal; Brody, Alan S; Bean, Judy; Salisbury, Shelia; Franz, David N 2008. Sirolimus for angiomyolipoma in tuberous sclerosis complex or lymphangioleiomyomatosis. The New England journal of medicine, 358 2, 140-51

McCormack, Francis X 2008. Lymphangioleiomyomatosis: a clinical update. Chest, 133 2, 507-16

Young, Lisa R; Inoue, Yoshikazu; McCormack, Francis X 2008. Diagnostic potential of serum VEGF-D for lymphangioleiomyomatosis. The New England journal of medicine, 358 2, 199-200

Byrnes, Abigail B; McCormack, Francis X; Diers, Tiffiny; Jazieh, Abdul-Rahman 2007. The resident scholar program: a research training opportunity for internal medicine house staff. Journal of cancer education : the official journal of the American Association for Cancer Education, 22 1, 47-9

Juvet, Stephen C; McCormack, Francis X; Kwiatkowski, David J; Downey, Gregory P 2007. Molecular pathogenesis of lymphangioleiomyomatosis: lessons learned from orphans. American journal of respiratory cell and molecular biology, 36 4, 398-408

McCormack, Francis X; Moss, Joel 2007. S-LAM in a man? American journal of respiratory and critical care medicine, 176 1, 3-5

Pollock-BarZiv, Stacey; Cohen, Marsha M; Downey, Gregory P; Johnson, Simon R; Sullivan, Eugene; McCormack, Francis X 2007. Air travel in women with lymphangioleiomyomatosis. Thorax, 62 2, 176-80

Young, Lisa R; Pasula, Rajamouli; Gulleman, Peter M; Deutsch, Gail H; McCormack, Francis X 2007. Susceptibility of Hermansky-Pudlak mice to bleomycin-induced type II cell apoptosis and fibrosis. American journal of respiratory cell and molecular biology, 37 1, 67-74

Zhang, Shiping; McCormack, Francis X; Levesque, Roger C; O'Toole, George A; Lau, Gee W 2007. The flagellum of Pseudomonas aeruginosa is required for resistance to clearance by surfactant protein A. PloS one, 2 6, e564

Almoosa, Khalid F; McCormack, Francis X; Sahn, Steven A 2006. Pleural disease in lymphangioleiomyomatosis. Clinics in chest medicine, 27 2, 355-68

Almoosa, Khalid F; Ryu, Jay H; Mendez, Jose; Huggins, J Terrill; Young, Lisa R; Sullivan, Eugene J; Maurer, Janet; McCormack, Francis X; Sahn, Steven A 2006. Management of pneumothorax in lymphangioleiomyomatosis: effects on recurrence and lung transplantation complications. Chest, 129 5, 1274-81

Kingma, Paul S; Zhang, Liqian; Ikegami, Machiko; Hartshorn, Kevan; McCormack, Francis X; Whitsett, Jeffrey A 2006. Correction of pulmonary abnormalities in Sftpd-/- mice requires the collagenous domain of surfactant protein D. The Journal of biological chemistry, 281 34, 24496-505

Kuzmenko, Alexander I; Wu, Huixing; McCormack, Francis X 2006. Pulmonary collectins selectively permeabilize model bacterial membranes containing rough lipopolysaccharide. Biochemistry, 45 8, 2679-85

McCormack, Francis X 2006. Lymphangioleiomyomatosis. MedGenMed : Medscape general medicine, 8 1, 15

McCormack, Francis X 2006. New concepts in collectin-mediated host defense at the air-liquid interface of the lung. Respirology (Carlton, Vic.), 11 Suppl , S7-10

Ryan, Marnie A; Akinbi, Henry T; Serrano, Alicia G; Perez-Gil, Jesus; Wu, Huixing; McCormack, Francis X; Weaver, Timothy E 2006. Antimicrobial activity of native and synthetic surfactant protein B peptides. Journal of immunology (Baltimore, Md. : 1950), 176 1, 416-25

Ryu, Jay H; Moss, Joel; Beck, Gerald J; Lee, Jar-Chi; Brown, Kevin K; Chapman, Jeffrey T; Finlay, Geraldine A; Olson, Eric J; Ruoss, Stephen J; Maurer, Janet R; Raffin, Thomas A; Peavy, Hannah H; McCarthy, Kevin; Taveira-Dasilva, Angelo; McCormack, Francis X; Avila, Nilo A; Decastro, Rosamma M; Jacobs, Susan S; Stylianou, Mario; Fanburg, Barry L 2006. The NHLBI lymphangioleiomyomatosis registry: characteristics of 230 patients at enrollment. American journal of respiratory and critical care medicine, 173 1, 105-11

Schlosser, A; Thomsen, T; Shipley, J M; Hein, P W; Brasch, F; Tornøe, I; Nielsen, O; Skjødt, K; Palaniyar, N; Steinhilber, W; McCormack, F X; Holmskov, U 2006. Microfibril-associated protein 4 binds to surfactant protein A (SP-A) and colocalizes with SP-A in the extracellular matrix of the lung. Scandinavian journal of immunology, 64 2, 104-16

Young, Lisa R; Almoosa, Khalid F; Pollock-Barziv, Stacey; Coutinho, Meg; McCormack, Francis X; Sahn, Steven A 2006. Patient perspectives on management of pneumothorax in lymphangioleiomyomatosis. Chest, 129 5, 1267-73

Young, Lisa R; Borchers, Michael T; Allen, Holly L; Gibbons, Reta S; McCormack, Francis X 2006. Lung-restricted macrophage activation in the pearl mouse model of Hermansky-Pudlak syndrome. Journal of immunology (Baltimore, Md. : 1950), 176 7, 4361-8

Zhang, Liqian; Ikegami, Machiko; Korfhagen, Thomas R; McCormack, Francis X; Yoshida, Mitsuhiro; Senior, Robert M; Shipley, J Michael; Shapiro, Steven D; Whitsett, Jeffrey A 2006. Neither SP-A nor NH2-terminal domains of SP-A can substitute for SP-D in regulation of alveolar homeostasis. American journal of physiology. Lung cellular and molecular physiology, 291 2, L181-90

Beharka, Alison A; Crowther, Joy E; McCormack, Francis X; Denning, Gerene M; Lees, Jason; Tibesar, Eric; Schlesinger, Larry S 2005. Pulmonary surfactant protein A activates a phosphatidylinositol 3-kinase/calcium signal transduction pathway in human macrophages: participation in the up-regulation of mannose receptor activity. Journal of immunology (Baltimore, Md. : 1950), 175 4, 2227-36

Kuzmenko, Alexander I; Wu, Huixing; Wan, Sijue; McCormack, Francis X 2005. Surfactant protein A is a principal and oxidation-sensitive microbial permeabilizing factor in the alveolar lining fluid. The Journal of biological chemistry, 280 27, 25913-9

Zhang, Shiping; Chen, Yi; Potvin, Eric; Sanschagrin, Francois; Levesque, Roger C; McCormack, Francis X; Lau, Gee W 2005. Comparative signature-tagged mutagenesis identifies Pseudomonas factors conferring resistance to the pulmonary collectin SP-A. PLoS pathogens, 1 3, 259-68

Crowther, Joy E; Kutala, Vijay Kumar; Kuppusamy, Periannan; Ferguson, J Scott; Beharka, Alison A; Zweier, Jay L; McCormack, Francis X; Schlesinger, Larry S 2004. Pulmonary surfactant protein a inhibits macrophage reactive oxygen intermediate production in response to stimuli by reducing NADPH oxidase activity. Journal of immunology (Baltimore, Md. : 1950), 172 11, 6866-74

Kuzmenko, A I; Wu, H; Bridges, J P; McCormack, F X 2004. Surfactant lipid peroxidation damages surfactant protein A and inhibits interactions with phospholipid vesicles. Journal of lipid research, 45 6, 1061-8

Schaeffer, Lyndsay M; McCormack, Francis X; Wu, Huixing; Weiss, Alison A 2004. Interactions of pulmonary collectins with Bordetella bronchiseptica and Bordetella pertussis lipopolysaccharide elucidate the structural basis of their antimicrobial activities. Infection and immunity, 72 12, 7124-30

Schaeffer, Lyndsay M; McCormack, Francis X; Wu, Huixing; Weiss, Alison A 2004. Bordetella pertussis lipopolysaccharide resists the bactericidal effects of pulmonary surfactant protein A. Journal of immunology (Baltimore, Md. : 1950), 173 3, 1959-65

Chabot, Sophie; Salez, Laurent; McCormack, Francis X; Touqui, Lhousseine; Chignard, Michel 2003. Surfactant protein A inhibits lipopolysaccharide-induced in vivo production of interleukin-10 by mononuclear phagocytes during lung inflammation. American journal of respiratory cell and molecular biology, 28 3, 347-53

Head, James F; Mealy, Tanya R; McCormack, Francis X; Seaton, Barbara A 2003. Crystal structure of trimeric carbohydrate recognition and neck domains of surfactant protein A. The Journal of biological chemistry, 278 44, 43254-60

Karbowniczek, Magdalena; Astrinidis, Aristotelis; Balsara, Binaifer R; Testa, Joseph R; Lium, James H; Colby, Thomas V; McCormack, Francis X; Henske, Elizabeth Petri 2003. Recurrent lymphangiomyomatosis after transplantation: genetic analyses reveal a metastatic mechanism. American journal of respiratory and critical care medicine, 167 7, 976-82

McCormack, Francis X; Gibbons, Reta; Ward, Susan R; Kuzmenko, Alexander; Wu, Huixing; Deepe, George S 2003. Macrophage-independent fungicidal action of the pulmonary collectins. The Journal of biological chemistry, 278 38, 36250-6

Rodriguez Capote, Karina; McCormack, Francis X; Possmayer, Fred 2003. Pulmonary surfactant protein-A (SP-A) restores the surface properties of surfactant after oxidation by a mechanism that requires the Cys6 interchain disulfide bond and the phospholipid binding domain. The Journal of biological chemistry, 278 23, 20461-74

Sietsema, Kathy E; McCormack, Francis X 2003. Lymphangioleiomyomatosis: insights about, and from, a rare disease. American journal of respiratory and critical care medicine, 168 12, 1405-6

Wu, Huixing; Kuzmenko, Alexander; Wan, Sijue; Schaffer, Lyndsay; Weiss, Alison; Fisher, James H; Kim, Kwang Sik; McCormack, Francis X 2003. Surfactant proteins A and D inhibit the growth of Gram-negative bacteria by increasing membrane permeability. The Journal of clinical investigation, 111 10, 1589-602

Beharka, Alison A; Gaynor, Cecilia D; Kang, Byoung K; Voelker, Dennis R; McCormack, Francis X; Schlesinger, Larry S 2002. Pulmonary surfactant protein A up-regulates activity of the mannose receptor, a pattern recognition receptor expressed on human macrophages. Journal of immunology (Baltimore, Md. : 1950), 169 7, 3565-73

Guillot, Loïc; Balloy, Viviane; McCormack, Francis X; Golenbock, Douglas T; Chignard, Michel; Si-Tahar, Mustapha 2002. Cutting edge: the immunostimulatory activity of the lung surfactant protein-A involves Toll-like receptor 4. Journal of immunology (Baltimore, Md. : 1950), 168 12, 5989-92

Malloy, Jaret L; Veldhuizen, Ruud A W; McCormack, Francis X; Korfhagen, Thomas R; Whitsett, Jeffery A; Lewis, James F 2002. Pulmonary surfactant and inflammation in septic adult mice: role of surfactant protein A. Journal of applied physiology (Bethesda, Md. : 1985), 92 2, 809-16

McCormack, Francis X; Whitsett, Jeffrey A 2002. The pulmonary collectins, SP-A and SP-D, orchestrate innate immunity in the lung. The Journal of clinical investigation, 109 6, 707-12

McCormack, Francis; Brody, Alan; Meyer, Christopher; Leonard, Jennifer; Chuck, Gail; Dabora, Sandra; Sethuraman, Gopalan; Colby, Thomas V; Kwiatkowski, David J; Franz, David N 2002. Pulmonary cysts consistent with lymphangioleiomyomatosis are common in women with tuberous sclerosis: genetic and radiographic analysis. Chest, 121 3 Suppl, 61S

Palaniyar, Nades; Zhang, Liquian; Kuzmenko, Alexander; Ikegami, Machiko; Wan, Sijue; Wu, Huixing; Korfhagen, Thomas R; Whitsett, Jeffrey A; McCormack, Francis X 2002. The role of pulmonary collectin N-terminal domains in surfactant structure, function, and homeostasis in vivo. The Journal of biological chemistry, 277 30, 26971-9

Franz, D N; Brody, A; Meyer, C; Leonard, J; Chuck, G; Dabora, S; Sethuraman, G; Colby, T V; Kwiatkowski, D J; McCormack, F X 2001. Mutational and radiographic analysis of pulmonary disease consistent with lymphangioleiomyomatosis and micronodular pneumocyte hyperplasia in women with tuberous sclerosis. American journal of respiratory and critical care medicine, 164 4, 661-8

Ikegami, M; Elhalwagi, B M; Palaniyar, N; Dienger, K; Korfhagen, T; Whitsett, J A; McCormack, F X 2001. The collagen-like region of surfactant protein A (SP-A) is required for correction of surfactant structural and functional defects in the SP-A null mouse. The Journal of biological chemistry, 276 42, 38542-8

Linke, M J; Harris, C E; Korfhagen, T R; McCormack, F X; Ashbaugh, A D; Steele, P; Whitsett, J A; Walzer, P D 2001. Immunosuppressed surfactant protein A-deficient mice have increased susceptibility to Pneumocystis carinii infection. The Journal of infectious diseases, 183 6, 943-52

Palaniyar, N; Ikegami, M; Korfhagen, T; Whitsett, J; McCormack, F X 2001. Domains of surfactant protein A that affect protein oligomerization, lipid structure and surface tension. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 129 1, 109-27

Salez, L; Balloy, V; van Rooijen, N; Lebastard, M; Touqui, L; McCormack, F X; Chignard, M 2001. Surfactant protein A suppresses lipopolysaccharide-induced IL-10 production by murine macrophages. Journal of immunology (Baltimore, Md. : 1950), 166 10, 6376-82

Bridges, J P; Davis, H W; Damodarasamy, M; Kuroki, Y; Howles, G; Hui, D Y; McCormack, F X 2000. Pulmonary surfactant proteins A and D are potent endogenous inhibitors of lipid peroxidation and oxidative cellular injury. The Journal of biological chemistry, 275 49, 38848-55

Damodarasamy, M; Zhang, M; Dienger, K; McCormack, F X 2000. Two rat surfactant protein A isoforms arise by a novel mechanism that includes alternative translation initiation. Biochemistry, 39 33, 10189-95

Fisher, J H; Sheftelyevich, V; Ho, Y S; Fligiel, S; McCormack, F X; Korfhagen, T R; Whitsett, J A; Ikegami, M 2000. Pulmonary-specific expression of SP-D corrects pulmonary lipid accumulation in SP-D gene-targeted mice. American journal of physiology. Lung cellular and molecular physiology, 278 2, L365-73

Palaniyar, N; McCormack, F X; Possmayer, F; Harauz, G 2000. Three-dimensional structure of rat surfactant protein A trimers in association with phospholipid monolayers. Biochemistry, 39 21, 6310-6

Elhalwagi, B M; Zhang, M; Ikegami, M; Iwamoto, H S; Morris, R E; Miller, M L; Dienger, K; McCormack, F X 1999. Normal surfactant pool sizes and inhibition-resistant surfactant from mice that overexpress surfactant protein A. American journal of respiratory cell and molecular biology, 21 3, 380-7

Ferguson, J S; Voelker, D R; McCormack, F X; Schlesinger, L S 1999. Surfactant protein D binds to Mycobacterium tuberculosis bacilli and lipoarabinomannan via carbohydrate-lectin interactions resulting in reduced phagocytosis of the bacteria by macrophages. Journal of immunology (Baltimore, Md. : 1950), 163 1, 312-21

McCormack, F X; Damodarasamy, M; Elhalwagi, B M 1999. Deletion mapping of N-terminal domains of surfactant protein A. The N-terminal segment is required for phospholipid aggregation and specific inhibition of surfactant secretion. The Journal of biological chemistry, 274 5, 3173-81

Yu, S H; McCormack, F X; Voelker, D R; Possmayer, F 1999. Interactions of pulmonary surfactant protein SP-A with monolayers of dipalmitoylphosphatidylcholine and cholesterol: roles of SP-A domains. Journal of lipid research, 40 5, 920-9

Borron, P; McCormack, F X; Elhalwagi, B M; Chroneos, Z C; Lewis, J F; Zhu, S; Wright, J R; Shepherd, V L; Possmayer, F; Inchley, K; Fraher, L J 1998. Surfactant protein A inhibits T cell proliferation via its collagen-like tail and a 210-kDa receptor. The American journal of physiology, 275 4 Pt 1, L679-86

McCormack, F X 1998. Structure, processing and properties of surfactant protein A. Biochimica et biophysica acta, 1408 2-3, 109-31

Pattanajitvilai, S; Kuroki, Y; Tsunezawa, W; McCormack, F X; Voelker, D R 1998. Mutational analysis of Arg197 of rat surfactant protein A. His197 creates specific lipid uptake defects. The Journal of biological chemistry, 273 10, 5702-7

Smolarek, T A; Wessner, L L; McCormack, F X; Mylet, J C; Menon, A G; Henske, E P 1998. Evidence that lymphangiomyomatosis is caused by TSC2 mutations: chromosome 16p13 loss of heterozygosity in angiomyolipomas and lymph nodes from women with lymphangiomyomatosis. American journal of human genetics, 62 4, 810-5

Sunkin, S M; Linke, M J; McCormack, F X; Walzer, P D; Stringer, J R 1998. Identification of a putative precursor to the major surface glycoprotein of Pneumocystis carinii. Infection and immunity, 66 2, 741-6

Tsunezawa, W; Sano, H; Sohma, H; McCormack, F X; Voelker, D R; Kuroki, Y 1998. Site-directed mutagenesis of surfactant protein A reveals dissociation of lipid aggregation and lipid uptake by alveolar type II cells. Biochimica et biophysica acta, 1387 1-2, 433-46

Zhang, M; Damodarasamy, M; Elhalwagi, B M; McCormack, F X 1998. The longer isoform and Cys-1 disulfide bridge of rat surfactant protein A are not essential for phospholipid and type II cell interactions. Biochemistry, 37 47, 16481-8

Blau, H; Riklis, S; Van Iwaarden, J F; McCormack, F X; Kalina, M 1997. Nitric oxide production by rat alveolar macrophages can be modulated in vitro by surfactant protein A. The American journal of physiology, 272 6 Pt 1, L1198-204

Elhalwagi, B M; Damodarasamy, M; McCormack, F X 1997. Alternate amino terminal processing of surfactant protein A results in cysteinyl isoforms required for multimer formation. Biochemistry, 36 23, 7018-25

McCormack, F 1997. The structure and function of surfactant protein-A. Chest, 111 6 Suppl, 114S-119S

McCormack, F X; Festa, A L; Andrews, R P; Linke, M; Walzer, P D 1997. The carbohydrate recognition domain of surfactant protein A mediates binding to the major surface glycoprotein of Pneumocystis carinii. Biochemistry, 36 26, 8092-9

McCormack, F X; Pattanajitvilai, S; Stewart, J; Possmayer, F; Inchley, K; Voelker, D R 1997. The Cys6 intermolecular disulfide bond and the collagen-like region of rat SP-A play critical roles in interactions with alveolar type II cells and surfactant lipids. The Journal of biological chemistry, 272 44, 27971-9

McCormack, F X; Stewart, J; Voelker, D R; Damodarasamy, M 1997. Alanine mutagenesis of surfactant protein A reveals that lipid binding and pH-dependent liposome aggregation are mediated by the carbohydrate recognition domain. Biochemistry, 36 45, 13963-71

Gaynor, C D; McCormack, F X; Voelker, D R; McGowan, S E; Schlesinger, L S 1995. Pulmonary surfactant protein A mediates enhanced phagocytosis of Mycobacterium tuberculosis by a direct interaction with human macrophages. Journal of immunology (Baltimore, Md. : 1950), 155 11, 5343-51

McCormack, F X; King, T E; Bucher, B L; Nielsen, L; Mason, R J; McCormac, F X 1995. Surfactant protein A predicts survival in idiopathic pulmonary fibrosis. American journal of respiratory and critical care medicine, 152 2, 751-9

Kuroki, Y; McCormack, F X; Ogasawara, Y; Mason, R J; Voelker, D R 1994. Epitope mapping for monoclonal antibodies identifies functional domains of pulmonary surfactant protein A that interact with lipids. The Journal of biological chemistry, 269 47, 29793-800

McCormack, F X; Calvert, H M; Watson, P A; Smith, D L; Mason, R J; Voelker, D R 1994. The structure and function of surfactant protein A. Hydroxyproline- and carbohydrate-deficient mutant proteins. The Journal of biological chemistry, 269 8, 5833-41

McCormack, F X; Kuroki, Y; Stewart, J J; Mason, R J; Voelker, D R 1994. Surfactant protein A amino acids Glu195 and Arg197 are essential for receptor binding, phospholipid aggregation, regulation of secretion, and the facilitated uptake of phospholipid by type II cells. The Journal of biological chemistry, 269 47, 29801-7

Ogasawara, Y; McCormack, F X; Mason, R J; Voelker, D R 1994. Chimeras of surfactant proteins A and D identify the carbohydrate recognition domains as essential for phospholipid interaction. The Journal of biological chemistry, 269 47, 29785-92

de Carvalho, M S; McCormack, F X; Leslie, C C 1993. The 85-kDa, arachidonic acid-specific phospholipase A2 is expressed as an activated phosphoprotein in Sf9 cells. Archives of biochemistry and biophysics, 306 2, 534-40

Kalina, M; McCormack, F X; Crowley, H; Voelker, D R; Mason, R J 1993. Internalization of surfactant protein A (SP-A) into lamellar bodies of rat alveolar type II cells in vitro. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 41 1, 57-70

Zimmerman, P E; Voelker, D R; McCormack, F X; Paulsrud, J R; Martin, W J 1992. 120-kD surface glycoprotein of Pneumocystis carinii is a ligand for surfactant protein A. The Journal of clinical investigation, 89 1, 143-9

Fisher, J H; McCormack, F; Park, S S; Stelzner, T; Shannon, J M; Hofmann, T 1991. In vivo regulation of surfactant proteins by glucocorticoids. American journal of respiratory cell and molecular biology, 5 1, 63-70

McCormack, F X; King, T E; Voelker, D R; Robinson, P C; Mason, R J 1991. Idiopathic pulmonary fibrosis. Abnormalities in the bronchoalveolar lavage content of surfactant protein A. The American review of respiratory disease, 144 1, 160-6

McCormack, F X; Fisher, J H; Suwabe, A; Smith, D L; Shannon, J M; Voelker, D R 1990. Expression and characterization of rat surfactant protein A synthesized in Chinese hamster ovary cells. Biochimica et biophysica acta, 1087 2, 190-8

Mackenzie, C F; Shin, B; Krishnaprasad, D; McCormack, F; Illingworth, W 1985. Assessment of cardiac and respiratory function during surgery on patients with acute quadriplegia. Journal of neurosurgery, 62 6, 843-9

Sykes, J A; McCormack, F X; O'Brien, T J 1978. A preliminary study of the superoxide dismutase content of some human tumors. Cancer research, 38 9, 2759-62

McCormack, F X . Functional mapping of surfactant protein A. Pediatric pathology & molecular medicine, 20 4, 293-318

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McCormack, Francis X . The way forward in lymphangioleiomyomatosis: a trial for every patient, every patient in a trial. Jornal brasileiro de pneumologia : publicaça?o oficial da Sociedade Brasileira de Pneumologia e Tisilogia, 37 4, 422-3