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Neurotrauma Lab

The Department of Neurosurgery Neurotrauma Laboratory is the laboratory of Dr. Laura Ngwenya, MD, PhD. The Neurotrauma Laboratory is affiliated with the UCGNI Neurotrauma Center, as well as the Collaborative for Research on Acute Neurological Injuries (CRANI). Traumatic brain injury (TBI) affects over 2.8 million people in the US annually. However, despite the widespread societal and economic impact, there are no effective treatments for traumatic brain injury. Especially devastating are the cognitive deficits that occur after TBI. The Neurotrauma Laboratory is a basic and translational laboratory that focuses on the mechanisms that underlie poor recovery after TBI. Using an experimental model of TBI, we examine acute and subacute cognitive deficits, and explore underlying mechanisms for potential treatments. We employ cognitive / behavioral testing, histology and immunohistochemistry, stereological quantification, electrophysiology, and molecular techniques. The current direction of our NIH funded laboratory is exploring the interplay between spreading depolarizations, adult neurogenesis, and TBI. We have many collaborators throughout UC and CCHMC, including Dr. Jennifer McGuire (Instructor, Dept. of Neurosurgery), Dr. Jed Hartings (Professor, Dept. of Neurosurgery), and Dr. Steve Danzer (Professor, Dept. of Anesthesia, CCHMC). Our lab’s ultimate goal is to discover the mechanisms that underlie poor recovery after TBI, such that we can design targeted therapies to improve patient outcomes.

2021

Wright, James M; Gerges, Christina; Shammassian, Berje; Labak, Collin M; Herring, Eric Z; Miller, Benjamin; Alkhachroum, Ayham; Kottapally, Mohan; Huang Wright, Christina; Rodgers, Richard B; Sedney, Cara; Ngwenya, Laura B; Stippler, Martina; Sieg, Emily; Babu, Maya A; Hoffer, Alan; Hejal, Rana 2021. Prone Position Ventilation in Neurologically Ill Patients: A Systematic Review and Proposed Protocol. Critical care medicine, ,

Robinson, Michael W; Prestigiacomo, Charles J; Ngwenya, Laura B 2021. Commentary: Intracerebral Hemorrhage Volume Reduction and Timing of Intervention Versus Functional Benefit and Survival in the MISTIE III and STICH Trials. Neurosurgery, 88 5, E394-E395

Xu, Linda B; Yue, John K; Korley, Frederick; Puccio, Ava M; Yuh, Esther L; Sun, Xiaoying; Rabinowitz, Miri; Vassar, Mary J; Taylor, Sabrina R; Winkler, Ethan A; Puffer, Ross C; Deng, Hansen; McCrea, Michael; Stein, Murray B; Robertson, Claudia S; Levin, Harvey S; Dikmen, Sureyya; Temkin, Nancy R; Giacino, Joseph T; Mukherjee, Pratik; Wang, Kevin K W; Okonkwo, David O; Markowitz, Amy J; Jain, Sonia; Manley, Geoffrey T; Diaz-Arrastia, Ramon 2021. High-Sensitivity C-Reactive Protein is a Prognostic Biomarker of Six-Month Disability after Traumatic Brain Injury: Results from the TRACK-TBI Study. Journal of neurotrauma, 38 7, 918-927

Levin, Harvey S; Temkin, Nancy R; Barber, Jason; Nelson, Lindsay D; Robertson, Claudia; Brennan, Jeffrey; Stein, Murray B; Yue, John K; Giacino, Joseph T; McCrea, Michael A; Diaz-Arrastia, Ramon; Mukherjee, Pratik; Okonkwo, David O; Boase, Kim; Markowitz, Amy J; Bodien, Yelena; Taylor, Sabrina; Vassar, Mary J; Manley, Geoffrey T ; Adeoye, Opeolu; Badjatia, Neeraj; Bullock, M Ross; Chesnut, Randall; Corrigan, John D; Crawford, Karen; Dikmen, Sureyya; Duhaime, Ann-Christine; Ellenbogen, Richard; Feeser, V Ramana; Ferguson, Adam R; Foreman, Brandon; Gardner, Raquel; Gaudette, Etienne; Gonzalez, Luis; Gopinath, Shankar; Gullapalli, Rao; Hemphill, J Claude; Hotz, Gillian; Jain, Sonia; Keene, C Dirk; Korley, Frederick K; Kramer, Joel; Kreitzer, Natalie; Lindsell, Chris; Machamer, Joan; Madden, Christopher; Martin, Alastair; McAllister, Thomas; Merchant, Randall; Nolan, Amber; Ngwenya, Laura B; Noel, Florence; Palacios, Eva; Puccio, Ava; Rabinowitz, Miri; Rosand, Jonathan; Sander, Angelle; Satris, Gabriella; Schnyer, David; Seabury, Seth; Sun, Xiaoying; Toga, Arthur; Valadka, Alex; Wang, Kevin; Yuh, Esther; Zafonte, Ross 2021. Association of Sex and Age With Mild Traumatic Brain Injury-Related Symptoms: A TRACK-TBI Study. JAMA network open, 4 4, e213046

Robinson, David; Pyle, Logan; Foreman, Brandon; Ngwenya, Laura B; Adeoye, Opeolu; Woo, Daniel; Kreitzer, Natalie 2021. Antithrombotic regimens and need for critical care interventions among patients with subdural hematomas. The American journal of emergency medicine, 47 , 6-12

Stein, Murray B; Yuh, Esther; Jain, Sonia; Okonkwo, David O; Mac Donald, Christine L; Levin, Harvey; Giacino, Joseph T; Dikmen, Sureyya; Vassar, Mary J; Diaz-Arrastia, Ramon; Robertson, Claudia S; Nelson, Lindsay D; McCrea, Michael; Sun, Xiaoying; Temkin, Nancy; Taylor, Sabrina R; Markowitz, Amy J; Manley, Geoffrey T; Mukherjee, Pratik 2021. Smaller Regional Brain Volumes Predict Posttraumatic Stress Disorder at 3 Months After Mild Traumatic Brain Injury. Biological psychiatry. Cognitive neuroscience and neuroimaging, 6 3, 352-359

Agtarap, Stephanie D; Campbell-Sills, Laura; Jain, Sonia; Sun, Xiaoying; Dikmen, Sureyya; Levin, Harvey; McCrea, Michael A; Mukherjee, Pratik; Nelson, Lindsay D; Temkin, Nancy; Yuh, Esther L; Giacino, Joseph T; Manley, Geoffrey T; Stein, Murray B 2021. Satisfaction with Life after Mild Traumatic Brain Injury: A TRACK-TBI Study. Journal of neurotrauma, 38 5, 546-554

Brett, Benjamin L; Kramer, Mark D; Whyte, John; McCrea, Michael A; Stein, Murray B; Giacino, Joseph T; Sherer, Mark; Markowitz, Amy J; Manley, Geoffrey T; Nelson, Lindsay D ; Adeoye, Opeolu; Badjatia, Neeraj; Boase, Kim; Barber, Jason; Bodien, Yelena; Bullock, M Ross; Chesnut, Randall; Corrigan, John D; Crawford, Karen; Diaz-Arrastia, Ramon; Dikmen, Sureyya; Duhaime, Ann-Christine; Ellenbogen, Richard; Feeser, V Ramana; Ferguson, Adam R; Foreman, Brandon; Gardner, Raquel; Gaudette, Etienne; Gonzalez, Luis; Gopinath, Shankar; Gullapalli, Rao; Hemphill, J Claude; Hotz, Gillian; Jain, Sonia; Keene, C Dirk; Korley, Frederick K; Kramer, Joel; Kreitzer, Natalie; Levin, Harvey; Lindsell, Chris; Machamer, Joan; Madden, Christopher; Martin, Alastair; McAllister, Thomas; Merchant, Randall; Mukherjee, Pratik; Ngwenya, Laura B; Noel, Florence; Okonkwo, David; Palacios, Eva; Puccio, Ava; Rabinowitz, Miri; Robertson, Claudia; Rosand, Jonathan; Sander, Angelle; Satris, Gabriella; Schnyer, David; Seabury, Seth; Taylor, Sabrina; Temkin, Nancy; Toga, Arthur; Valadka, Alex; Vassar, Mary; Wang, Kevin; Yue, John K; Yuh, Esther; Zafonte, Ross 2021. Latent Profile Analysis of Neuropsychiatric Symptoms and Cognitive Function of Adults 2 Weeks After Traumatic Brain Injury: Findings From the TRACK-TBI Study. JAMA network open, 4 3, e213467

Casillo, Stephanie M; Venkatesh, Anisha; Muthiah, Nallammai; Agarwal, Nitin; Scott, Teresa; Romani, Rossana; Fernández, Laura L; Aristizabal, Sarita; Ginalis, Elizabeth E; Ozair, Ahmad; Bhat, Vivek; Faruqi, Arjumand; Bajaj, Ankur; Sonkar, Abhinav Arun; Ikeda, Daniel S; Chiocca, E Antonio; Lonser, Russell R; Sutton, Tracy E; McGregor, John M; Rea, Gary L; Schunemann, Victoria A; Ngwenya, Laura B; Marlin, Evan S; Porensky, Paul N; Shaikhouni, Ammar; Huntoon, Kristin; Dornbos, David; Shaw, Andrew B; Powers, Ciarán J; Gluski, Jacob M; Culver, Lauren G; Goodwin, Alyssa M; Ham, Steven; Marupudi, Neena I; Bhat, Dhananjaya I; Berry, Katherine M; Wu, Eva M; Wang, Michael Y 2021. Biographies of international women leaders in neurosurgery. Neurosurgical focus, 50 3, E19

Nolan, Amber L; Petersen, Cathrine; Iacono, Diego; Mac Donald, Christine L; Mukherjee, Pratik; van der Kouwe, Andre; Jain, Sonia; Stevens, Allison; Diamond, Bram R; Wang, Ruopeng; Markowitz, Amy J; Fischl, Bruce; Perl, Daniel P; Manley, Geoffrey T; Keene, C Dirk; Diaz-Arrastia, Ramon; Edlow, Brian L 2021. Tractography-Pathology Correlations in Traumatic Brain Injury: A TRACK-TBI Study. Journal of neurotrauma, ,

Correll, Erika A; Ramser, Benjamin J; Knott, Maxon V; McCullumsmith, Robert E; McGuire, Jennifer L; Ngwenya, Laura B 2021. Deficits in pattern separation and dentate gyrus proliferation after rodent lateral fluid percussion injury. IBRO neuroscience reports, 10 , 31-41

Krishnamoorthy, Vijay; Temkin, Nancy; Barber, Jason; Foreman, Brandon; Komisarow, Jordan; Korley, Fred K; Laskowitz, Daniel T; Mathew, Joseph P; Hernandez, Adrian; Sampson, John; James, Michael L; Bartz, Raquel; Raghunathan, Karthik; Goldstein, Benjamin A; Markowitz, Amy J; Vavilala, Monica S 2021. Association of Early Multiple Organ Dysfunction With Clinical and Functional Outcomes Over the Year Following Traumatic Brain Injury: A Transforming Research and Clinical Knowledge in Traumatic Brain Injury Study. Critical care medicine, 49 10, 1769-1778

Boase, Kim; Machamer, Joan; Temkin, Nancy R; Dikmen, Sureyya; Wilson, Lindsay; Nelson, Lindsay D; Barber, Jason; Bodien, Yelena G; Giacino, Joseph T; Markowitz, Amy J; McCrea, Michael A; Satris, Gabriela; Stein, Murray B; Taylor, Sabrina R; Manley, Geoffrey T 2021. Central Curation of Glasgow Outcome Scale-Extended Data: Lessons Learned from TRACK-TBI. Journal of neurotrauma, 38 17, 2419-2434

Yuh, Esther L; Jain, Sonia; Sun, Xiaoying; Pisica, Dana; Harris, Mark H; Taylor, Sabrina R; Markowitz, Amy J; Mukherjee, Pratik; Verheyden, Jan; Giacino, Joseph T; Levin, Harvey S; McCrea, Michael; Stein, Murray B; Temkin, Nancy R; Diaz-Arrastia, Ramon; Robertson, Claudia S; Lingsma, Hester F; Okonkwo, David O; Maas, Andrew I R; Manley, Geoffrey T ; Adeoye, Opeolu; Badjatia, Neeraj; Boase, Kim; Bodien, Yelena; Corrigan, John D; Crawford, Karen; Dikmen, Sureyya; Duhaime, Ann-Christine; Ellenbogen, Richard; Feeser, V Ramana; Ferguson, Adam R; Foreman, Brandon; Gardner, Raquel; Gaudette, Etienne; Gonzalez, Luis; Gopinath, Shankar; Gullapalli, Rao; Hemphill, J Claude; Hotz, Gillian; Keene, C Dirk; Kramer, Joel; Kreitzer, Natalie; Lindsell, Chris; Machamer, Joan; Madden, Christopher; Martin, Alastair; McAllister, Thomas; Merchant, Randall; Nelson, Lindsay; Ngwenya, Laura B; Noel, Florence; Nolan, Amber; Palacios, Eva; Perl, Daniel; Rabinowitz, Miri; Rosand, Jonathan; Sander, Angelle; Satris, Gabriella; Schnyer, David; Seabury, Seth; Toga, Arthur; Valadka, Alex; Vassar, Mary; Zafonte, Ross 2021. Pathological Computed Tomography Features Associated With Adverse Outcomes After Mild Traumatic Brain Injury: A TRACK-TBI Study With External Validation in CENTER-TBI. JAMA neurology, 78 9, 1137-1148

McCrea, Michael A; Giacino, Joseph T; Barber, Jason; Temkin, Nancy R; Nelson, Lindsay D; Levin, Harvey S; Dikmen, Sureyya; Stein, Murray; Bodien, Yelena G; Boase, Kim; Taylor, Sabrina R; Vassar, Mary; Mukherjee, Pratik; Robertson, Claudia; Diaz-Arrastia, Ramon; Okonkwo, David O; Markowitz, Amy J; Manley, Geoffrey T ; Adeoye, Opeolu; Badjatia, Neeraj; Bullock, M Ross; Chesnut, Randall; Corrigan, John D; Crawford, Karen; Duhaime, Ann-Christine; Ellenbogen, Richard; Feeser, V Ramana; Ferguson, Adam R; Foreman, Brandon; Gardner, Raquel; Gaudette, Etienne; Goldman, Dana; Gonzalez, Luis; Gopinath, Shankar; Gullapalli, Rao; Hemphill, J Claude; Hotz, Gillian; Jain, Sonia; Keene, C Dirk; Korley, Frederick K; Kramer, Joel; Kreitzer, Natalie; Lindsell, Chris; Machamer, Joan; Madden, Christopher; Martin, Alastair; McAllister, Thomas; Merchant, Randall; Ngwenya, Laura B; Noel, Florence; Nolan, Amber; Palacios, Eva; Perl, Daniel; Puccio, Ava; Rabinowitz, Miri; Rosand, Jonathan; Sander, Angelle; Satris, Gabriella; Schnyer, David; Seabury, Seth; Sherer, Mark; Toga, Arthur; Valadka, Alex; Wang, Kevin; Yue, John K; Yuh, Esther; Zafonte, Ross 2021. Functional Outcomes Over the First Year After Moderate to Severe Traumatic Brain Injury in the Prospective, Longitudinal TRACK-TBI Study. JAMA neurology, 78 8, 982-992

Knott, Maxon V; Ngwenya, Laura B; Correll, Erika A; Bohnert, Judy; Ziemba, Noah J; Allgire, Emily; Hopkins, Tracy; McGuire, Jennifer L 2021. Lack of Glutamate Receptor Subunit Expression Changes in Hippocampal Dentate Gyrus after Experimental Traumatic Brain Injury in a Rodent Model of Depression. International journal of molecular sciences, 22 15,

Williams, John R; Nieblas-Bedolla, Edwin; Feroze, Abdullah; Young, Christopher; Temkin, Nancy R; Giacino, Joseph T; Okonkwo, David O; Manley, Geoffrey T; Barber, Jason; Durfy, Sharon; Markowitz, Amy J; Yuh, Esther L; Mukherjee, Pratik; Mac Donald, Christine L 2021. Prognostic Value of Hemorrhagic Brainstem Injury on Early Computed Tomography: A TRACK-TBI Study. Neurocritical care, ,

Robinson, David; Kreitzer, Natalie; Ngwenya, Laura B; Adeoye, Opeolu; Woo, Daniel; Hartings, Jed; Foreman, Brandon 2021. Diffusion-Weighted Imaging Reveals Distinct Patterns of Cytotoxic Edema in Patients with Subdural Hematomas. Journal of neurotrauma, ,

Foreman, Brandon; Lee, Hyunjo; Mizrahi, Moshe A; Hartings, Jed A; Ngwenya, Laura B; Privitera, Michael; Tortella, Frank C; Zhang, Nanhua; Kramer, Joel H 2021. Seizures and Cognitive Outcome After Traumatic Brain Injury: A Post Hoc Analysis. Neurocritical care, ,

Wright, James; Elder, Theresa; Gerges, Christina; Reisen, Breanne; Wright, Christina; Jella, Tarun; Shah, Sanjit; Yang, George; Ngwenya, Laura B; Wang, Vincent; Parr, Ann M 2021. A systematic review of telehealth for the delivery of emergent neurosurgical care. Journal of telemedicine and telecare, 27 5, 261-268

2020

Robinson, David; Pyle, Logan; Foreman, Brandon; Ngwenya, Laura B; Adeoye, Opeolu; Woo, Daniel; Kreitzer, Natalie 2020. Factors Associated with Early versus Delayed Expansion of Acute Subdural Hematomas Initially Managed Conservatively. Journal of neurotrauma, ,

Matur, Abhijith V; Ngwenya, Laura B; Prestigiacomo, Charles J 2020. The surgical history of head injury in motor vehicle collision. Journal of neurosurgery, , 1-7

Barhorst, Kinsey A; Alfawares, Yara; McGuire, Jennifer L; Danzer, Steve C; Hartings, Jed A; Ngwenya, Laura B 2020. Remote and Persistent Alterations in Glutamate Receptor Subunit Composition Induced by Spreading Depolarizations in Rat Brain. Cellular and molecular neurobiology, ,

Shah, Sanjit; Yang, George L; Le, Diana T; Gerges, Christina; Wright, James M; Parr, Ann M; Cheng, Joseph S; Ngwenya, Laura B 2020. Examining the Emergency Medical Treatment and Active Labor Act: impact on telemedicine for neurotrauma. Neurosurgical focus, 49 5, E8

Le, Diana T; Barhorst, Kinsey A; Castiglione, James; Yang, George L; Shah, Sanjit J; Harlan, Sarah S; Keegan, Shaun P; Jandarov, Roman A; Ngwenya, Laura B; Prestigiacomo, Charles J 2020. Blunt cerebrovascular injury in the geriatric population. Neurosurgical focus, 49 4, E10

Rath, Kelly; Kreitzer, Natalie; Schlichter, Erika; Lopez, Omar; Ferioli, Simona; Ngwenya, Laura B; Foreman, Brandon 2020. The Experience of a Neurocritical Care Admission and Discharge for Patients and Their Families: A Qualitative Analysis. The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses, 52 4, 179-185

Rhame, Katherine; Le, Diana; Ventura, Amanda; Horner, Amy; Andaluz, Norberto; Miller, Christopher; Stolz, Uwe; Ngwenya, Laura B; Adeoye, Opeolu; Kreitzer, Natalie 2020. Management of the mild traumatic brain injured patient using a multidisciplinary observation unit protocol. The American journal of emergency medicine, ,

Porter, Zachary R; Mejia-Munne, Juan C; Krueger, Bryan M; Kosty, Jennifer A; Ngwenya, Laura B 2020. Sacral Rheumatoid Nodule: An Unusual Indication for Coccygectomy. Case reports in surgery, 2020 , 2757625

Rhame, Katherine; Le, Diana; Horner, Amy; Thomas, Andrea; Foreman, Brandon P; Kreitzer, Natalie P; Ngwenya, Laura B 2020. Implementation of a Neurotrauma Hotline for post-hospital continuity of care. Acta neurologica Scandinavica, 141 4, 351-354

Hartings, Jed A; Andaluz, Norberto; Bullock, M Ross; Hinzman, Jason M; Mathern, Bruce; Pahl, Clemens; Puccio, Ava; Shutter, Lori A; Strong, Anthony J; Vagal, Achala; Wilson, J Adam; Dreier, Jens P; Ngwenya, Laura B; Foreman, Brandon; Pahren, Laura; Lingsma, Hester; Okonkwo, David O 2020. Prognostic Value of Spreading Depolarizations in Patients With Severe Traumatic Brain Injury. JAMA neurology, 77 4, 489-499

Ngwenya, Laura B 2020. Commentary: Concussion Guidelines Step 2: Evidence for Subtype Classification. Neurosurgery, 86 1, E1

Okonkwo, David O; Puffer, Ross C; Puccio, Ava M; Yuh, Esther L; Yue, John K; Diaz-Arrastia, Ramon; Korley, Frederick K; Wang, Kevin K W; Sun, Xiaoying; Taylor, Sabrina R; Mukherjee, Pratik; Markowitz, Amy J; Jain, Sonia; Manley, Geoffrey T 2020. Point-of-Care Platform Blood Biomarker Testing of Glial Fibrillary Acidic Protein versus S100 Calcium-Binding Protein B for Prediction of Traumatic Brain Injuries: A Transforming Research and Clinical Knowledge in Traumatic Brain Injury Study. Journal of neurotrauma, 37 23, 2460-2467

Simpkins, Alexis N; Busl, Katharina M; Amorim, Edilberto; Barnett-Tapia, Carolina; Cervenka, Mackenzie C; Dhakar, Monica B; Etherton, Mark R; Fung, Celia; Griggs, Robert; Holloway, Robert G; Kelly, Adam G; Khan, Imad R; Lizarraga, Karlo J; Madagan, Hannah G; Onweni, Chidinma L; Mestre, Humberto; Rabinstein, Alejandro A; Rubinos, Clio; Dionisio-Santos, Dawling A; Youn, Teddy S; Merck, Lisa H; Maciel, Carolina B 2020. Proceedings from the Neurotherapeutics Symposium on Neurological Emergencies: Shaping the Future of Neurocritical Care. Neurocritical care, 33 3, 636-645

Evans, Emily; Cook, Nathan E; Iverson, Grant L; Townsend, Elise L; Duhaime, Ann-Christine 2020. Monitoring Outcome after Hospital-Presenting Milder Spectrum Pediatric Traumatic Brain Injury Using the Glasgow Outcome Scale-Extended, Pediatric Revision. Journal of neurotrauma, 37 14, 1627-1636

Agtarap, Stephanie; Kramer, Mark D; Campbell-Sills, Laura; Yuh, Esther; Mukherjee, Pratik; Manley, Geoffrey T; McCrea, Michael A; Dikmen, Sureyya; Giacino, Joseph T; Stein, Murray B; Nelson, Lindsay D 2020. Invariance of the Bifactor Structure of Mild Traumatic Brain Injury (mTBI) Symptoms on the Rivermead Postconcussion Symptoms Questionnaire Across Time, Demographic Characteristics, and Clinical Groups: A TRACK-TBI Study. Assessment, , 1073191120913941

Huie, J Russell; Mondello, Stefania; Lindsell, Christopher J; Antiga, Luca; Yuh, Esther L; Zanier, Elisa R; Masson, Serge; Rosario, Bedda L; Ferguson, Adam R 2020. Biomarkers for Traumatic Brain Injury: Data Standards and Statistical Considerations. Journal of neurotrauma, ,

Nielson, Jessica L; Cooper, Shelly R; Seabury, Seth A; Luciani, Davide; Fabio, Anthony; Temkin, Nancy R; Ferguson, Adam R 2020. Statistical Guidelines for Handling Missing Data in Traumatic Brain Injury Clinical Research. Journal of neurotrauma, ,

2019

McGuire, Jennifer L; Correll, Erika A; Lowery, Alexandra C; Rhame, Katherine; Anwar, Fatima N; McCullumsmith, Robert E; Ngwenya, Laura B 2019. Pioglitazone improves working memory performance when administered in chronic TBI. Neurobiology of disease, 132 , 104611

Dossani, Rimal H; Terrell, Danielle; Kosty, Jennifer A; Ross, Robert C; Demand, Audrey; Wild, Elizabeth; Peterson, Racheal; Ngwenya, Laura B; Benzil, Deborah L; Notarianni, Christina 2019. Gender disparities in academic rank achievement in neurosurgery: a critical assessment. Journal of neurosurgery, , 1-6

Khalid, Fatima; Yang, George L; McGuire, Jennifer L; Robson, Matthew J; Foreman, Brandon; Ngwenya, Laura B; Lorenz, John N 2019. Autonomic dysfunction following traumatic brain injury: translational insights. Neurosurgical focus, 47 5, E8

Burke, John F; Yue, John K; Ngwenya, Laura B; Winkler, Ethan A; Talbott, Jason F; Pan, Jonathan Z; Ferguson, Adam R; Beattie, Michael S; Bresnahan, Jacqueline C; Haefeli, Jenny; Whetstone, William D; Suen, Catherine G; Huang, Michael C; Manley, Geoffrey T; Tarapore, Phiroz E; Dhall, Sanjay S 2019. In Reply: Ultra-Early (<12 Hours) Surgery Correlates With Higher Rate of American Spinal Injury Association Impairment Scale Conversion After Cervical Spinal Cord Injury. Neurosurgery, 85 2, E401-E402

Burke, John F; Yue, John K; Ngwenya, Laura B; Winkler, Ethan A; Talbott, Jason F; Pan, Jonathan Z; Ferguson, Adam R; Beattie, Michael S; Bresnahan, Jacqueline C; Haefeli, Jenny; Whetstone, William D; Suen, Catherine G; Huang, Michael C; Manley, Geoffrey T; Tarapore, Phiroz E; Dhall, Sanjay S 2019. Ultra-Early (<12 Hours) Surgery Correlates With Higher Rate of American Spinal Injury Association Impairment Scale Conversion After Cervical Spinal Cord Injury. Neurosurgery, 85 2, 199-203

McGuire, Jennifer L; Ngwenya, Laura B; McCullumsmith, Robert E 2019. Neurotransmitter changes after traumatic brain injury: an update for new treatment strategies. Molecular psychiatry, 24 7, 995-1012

Lee, Hyunjo; Mizrahi, Moshe A; Hartings, Jed A; Sharma, Sameer; Pahren, Laura; Ngwenya, Laura B; Moseley, Brian D; Privitera, Michael; Tortella, Frank C; Foreman, Brandon 2019. Continuous Electroencephalography After Moderate to Severe Traumatic Brain Injury. Critical care medicine, 47 4, 574-582

Foreman, Brandon; Cass, Daryn; Forbes, Jonathan; Ngwenya, Laura B 2019. A Bedside, Single Burr Hole Approach to Multimodality Monitoring in Severe Brain Injury. Journal of visualized experiments : JoVE, 145,

Foreman, Brandon; Ngwenya, Laura B 2019. The Sustainability of Applied Intracranial Multimodality Neuromonitoring after Severe Brain Injury. World neurosurgery, ,

2018

Hartings, Jed A; Ngwenya, Laura B; Carroll, Christopher P; Foreman, Brandon 2018. Letter to the Editor. Ketamine sedation for the suppression of spreading depolarizations. Journal of neurosurgery, , 1-2

McGuire, Jennifer L; DePasquale, Erica A K; Watanabe, Miki; Anwar, Fatima; Ngwenya, Laura B; Atluri, Gowtham; Romick-Rosendale, Lindsey E; McCullumsmith, Robert E; Evanson, Nathan K 2018. Chronic Dysregulation of Cortical and Subcortical Metabolism After Experimental Traumatic Brain Injury. Molecular neurobiology, ,

Foreman, Brandon; Ngwenya, Laura B; Stoddard, Erica; Hinzman, Jason M; Andaluz, Norberto; Hartings, Jed A 2018. Safety and Reliability of Bedside, Single Burr Hole Technique for Intracranial Multimodality Monitoring in Severe Traumatic Brain Injury. Neurocritical care, ,

Hartings, Jed A; Ngwenya, Laura B; Watanabe, Tomas; Foreman, Brandon 2018. Commentary: Detecting Cortical Spreading Depolarization with Full Band Scalp Electroencephalography: An Illusion? Frontiers in systems neuroscience, 12 , 19

Ngwenya, Laura B; Mazumder, Sarmistha; Porter, Zachary R; Minnema, Amy; Oswald, Duane J; Farhadi, H Francis 2018. Implantation of Neuronal Stem Cells Enhances Object Recognition without Increasing Neurogenesis after Lateral Fluid Percussion Injury in Mice. Stem cells international, 2018 , 4209821

Ngwenya, Laura B; Gardner, Raquel C; Yue, John K; Burke, John F; Ferguson, Adam R; Huang, Michael C; Winkler, Ethan A; Pirracchio, Romain; Satris, Gabriela G; Yuh, Esther L; Mukherjee, Pratik; Valadka, Alex B; Okonkwo, David O; Manley, Geoffrey T 2018. Concordance of common data elements for assessment of subjective cognitive complaints after mild-traumatic brain injury: a TRACK-TBI Pilot Study. Brain injury, 32 9, 1071-1078

Ngwenya, Laura B; Danzer, Steve C 2018. Impact of Traumatic Brain Injury on Neurogenesis. Frontiers in neuroscience, 12 , 1014

2017

Estrada, Larissa I; Robinson, Amy A; Amaral, Ana C; Giannaris, Eustathia L; Heyworth, Nadine C; Mortazavi, Farzad; Ngwenya, Laura B; Roberts, Debra E; Cabral, Howard J; Killiany, Ronald J; Rosene, Douglas L 2017. Evaluation of Long-Term Cryostorage of Brain Tissue Sections for Quantitative Histochemistry. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 65 3, 153-171

Ngwenya, Laura B; Suen, Catherine G; Tarapore, Phiroz E; Manley, Geoffrey T; Huang, Michael C 2017. Safety and cost efficiency of a restrictive transfusion protocol in patients with traumatic brain injury. Journal of neurosurgery, , 1-8

Yue, John K; Ngwenya, Laura B; Upadhyayula, Pavan S; Deng, Hansen; Winkler, Ethan A; Burke, John F; Lee, Young M; Robinson, Caitlin K; Ferguson, Adam R; Lingsma, Hester F; Cnossen, Maryse C; Pirracchio, Romain; Korley, Frederick K; Vassar, Mary J; Yuh, Esther L; Mukherjee, Pratik; Gordon, Wayne A; Valadka, Alex B; Okonkwo, David O; Manley, Geoffrey T 2017. Emergency department blood alcohol level associates with injury factors and six-month outcome after uncomplicated mild traumatic brain injury. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, ,

Yue, John K; Burke, John F; Upadhyayula, Pavan S; Winkler, Ethan A; Deng, Hansen; Robinson, Caitlin K; Pirracchio, Romain; Suen, Catherine G; Sharma, Sourabh; Ferguson, Adam R; Ngwenya, Laura B; Stein, Murray B; Manley, Geoffrey T; Tarapore, Phiroz E 2017. Selective Serotonin Reuptake Inhibitors for Treating Neurocognitive and Neuropsychiatric Disorders Following Traumatic Brain Injury: An Evaluation of Current Evidence. Brain sciences, 7 8,

Martin, Grace E; Carroll, Christopher P; Plummer, Zach J; Millar, D A; Pritts, Timothy A; Makley, Amy T; Joseph, Bellal A; Ngwenya, Laura B; Goodman, Michael D 2017. Safety and Efficacy of Brain Injury Guidelines at a Level III Trauma Center. The journal of trauma and acute care surgery, ,

Yue, John K; Robinson, Caitlin K; Winkler, Ethan A; Upadhyayula, Pavan S; Burke, John F; Pirracchio, Romain; Suen, Catherine G; Deng, Hansen; Ngwenya, Laura B; Dhall, Sanjay S; Manley, Geoffrey T; Tarapore, Phiroz E 2017. Circadian variability of the initial Glasgow Coma Scale score in traumatic brain injury patients. Neurobiology of sleep and circadian rhythms, 2 , 85-93

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University of Cincinnati
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Department of Neurosurgery
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Cincinnati Ohio 45267-0515