Coronavirus COVID-19 Updates: uc.edu/publichealth
Congratulations to Mary Bedard, MSTP/CCB PhD student (Dr. Susa Wells’s Lab) for receiving a F30 Award for the application "Single Cell RNAseq Guides Discovery of Viral and Cellular Drivers of RRP pathologies" from the National Institute of Allergy and Infectious Diseases. Mary's focus is on pediatric recurrent respiratory papillomatosis (RRP), a persistent HPV-driven disease that carries significant morbidity in the absence of FDA-approved treatment options. She will leverage single cell transcriptomics data from papillomatous versus non-diseased laryngeal tissues from recruited patients to define and test predictive markers and key effectors of disease development. A diverse team of researchers, physicians and clinicians at CCHMC and UC supports this highly translational project.
Congratulations to Zhiyun Yu, Cancer & Cell Biology PhD Program Graduate Assistant in Dr. Mingxia Gu’s Lab for her AHA Predoctoral Award for her project: “Elucidate the abnormal phenotypes of coronary arterial endothelial cells in Hypoplastic Left Heart Syndrome”
Defense of Doctor of Philosophy Dissertation held: Tuesday, October 15, 2019
Title: “Mechanisms regulating cancer cell sensitivity and acquired resistance to inhibition of Stearoyl-CoA Desaturase”
Defense of Doctor of Philosophy Dissertation held: Wednesday, October 23, 2019
Title: “Overcoming Breast Cancer Metastasis with Novel RNA Aptamers”
Defense of Doctor of Philosophy Dissertation held: Tuesday, November 5, 2019
Title: “Modeling Fanconi Anemia in Squamous Epithelium using Human Induced Pluripotent Stem Cell-Derived Organoids”
Defense of Doctor of Philosophy Dissertation held: Wednesday, November 20, 2019
Title: “NF1 Patient Missense Variants Predict a Role for ATM in Modifying Neurofibroma Initiation”
Mark Jordan Althoff
Defense of Doctor of Philosophy Dissertation held: Tuesday, February 25th, 2020.
Title: “Cell polarity in hematopoietic stem cell quiescence, signaling and fate determination”
Defense of Doctor of Philosophy Dissertation held: Monday, April 20, 2020
Title: “Transcriptional regulation of lung diseases by Fox proteins”
Defense of Doctor of Philosophy Dissertation held: Wednesday, April 29th, 2020
Title: "TIFAB Links Innate Immune Signaling to the Cellular Stress Response in Myeloid Malignancies"
Defense of Doctor of Philosophy Dissertation held: Thursday, June 4th, 2020
Title: “The RON receptor tyrosine kinase drives immunosuppression in prostate cancer"
Defense of Doctor of Philosophy Dissertation held: Thursday, June 11th, 2020
Title: “Regulation of tumor growth and progression by Focal Adhesion Kinase (FAK) in a murine model of basal-like Breast Cancer”
5/15/2020: Congratulations to our incoming 2020 Cancer and Cell Biology Graduate Program students Angelle Jones and Timothy Nixon. Both students were selected from a highly competitive pool of nominees to join the Albert C. Yates Fellowship Program. The mission of the Yates Fellowship Program at the University of Cincinnati is to enrich the education and environment for all graduate students by supporting the recruitment and retention of underrepresented minority groups with high potential for academic success in graduate programs at UC. The Yates Fellowship Program will provide Angelle and Timothy additional stipend funding disbursed over 5 years.
3/4/20: Both graduate students in the Cancer & Cell Biology Graduate Program, Ayusman and Laurel were awarded the Graduate Student Government Research Fellowship award, which provides a monetary prize towards their research expenses.
Congratulations Vivienne Woo (Theresa Alenghat’s Lab)
Vivienne’s thesis work aims to determine how commensal bacteria in the intestine promote host defense against pathogenic infections. Interactions between the intestinal microbiota and the mammalian host are essential for effective defense against pathogenic infection. However, the underlying mechanisms by which protective microbial cues are integrated by host cells remain unclear. Vivienne’s work demonstrates that commensal bacteria epigenetically regulate intestinal epithelial cells to decrease infection in mice. Importantly, Vivienne uncovered that commensal bacteria may provide a direct source of metabolites in the intestine that allow commensal bacteria to calibrate epithelial defenses in the intestine.
The Program sincerely thanks Dr. and Mrs. Cardell for their continued support of the CCB Graduate Program and for honoring excellence in cancer and cell biological research. Dr. Cardell was the former Chair of Cell Biology and the founder of the departmental graduate program. During his tenure, he built the Department into a nationally recognized research unit and later served as Associate Dean for Graduate Education. Emma Lou Cardell was an outstanding electron microscopist, histologist, and teacher. They established the Cardell Fellowship in 1999 through a gift to the UC Foundation that supports an annual award for the recipient. This year recipient will receive $2,000 to use for professional development, and will give a special departmental seminar during the Fall semester.
Many thanks also go out to the dedicated and thoughtful members of the Selection Committee: Dave Plas (Chair), Zalfa Abdel-Malek, Chunying Du, Daniel Starczynowski, and Jordan Althoff (student representative). In addition to reviewing the applications and selecting the recipients, the Committee has been instrumental in providing feedback on the content, form and process for the fellowship that have materially improved the Fellowship procedures.
11/26/19. CCB Alumni, faculty, students, staff, friends and family gather to honor the memory of Dr. Robert Cardell on Thursday, November 21, 2019 at the Vontz Center for Molecular Studies.
Dr Cardell was a former Chair of the Department and a strong supporter of graduate education. In addition, he was a mentor and friend of many. Dr Cardell will be dearly miss by our faculty, staff and students although his legacy will live on. We not only celebrate Dr Cardell and his scientific accomplishments, but the lasting impact that he has had in all of our lives. The Cardell Fellowship presented today marks the 20th year of this award, with the first Cardell Fellowship recipient being named in 1999. Dr Cardell established this fellowship to provide support for graduate students so they could advance their research careers. In addition to providing funds to the student, Dr. and Mrs. Cardell would have lunch with the Fellowship recipient, their mentor, and the fellowship selection committee to celebrate. While the lunches may not continue, the excellence of the Cardell Fellowship Program will. Having met the Cardell’s as part of this Fellowship program and as the current Director of the Cancer and Cell Biology Graduate Program, I can attest to the large number of outstanding Cardell Fellows that have been supported though his generosity. These fellows, along with those to come, will continue to serve as a small part of Dr Cardell’s legacy.
On a personal note, I had the pleasure of getting to know Bob well as a few of my graduate students received the Cardell Fellowship. Through the years, he became a mentor and friend. I will dearly miss our talks, lunches, and seeing him at our seminars and events. I thank him for his support and for fueling my passion for graduate education. He had an infectious love for science and education which will live on in the hearts and lives of the many people he has touch.
We honor Dr. Cardell for being an inspiration for many and thank him for being a wonderful friend, teacher and mentor.
Susan E. Waltz, Ph.D.
Department of Cancer Biology
Director, Cancer & Cell Biology Graduate Program
University of Cincinnati College of Medicine
Vontz Center for Molecular Studie
Most weeks in the Cincinnati Business Courier, UC College of Medicine faculty are featured in advertisements to highlight their research achievements, educational strengths and clinical expertise. The Sept. 27 issue featured Ken Greis, PhD, professor in the Department of Cancer Biology and associate dean for research core facilities.
Source: DEAN'S LIST Weekly News from the College of Medicine: Sept. 30, 2019
Jordan’s thesis work aims to understand how cellular polarity regulates hematopoietic stem cell (HSC) self-renewal. Work from this project reveals that the spatial restriction or polarization of Scribble (a multi-modular scaffolding protein) coordinates the organization and activation of the Hippo Signaling Pathway within HSC. Notably, Scribble deficient HSC lose upstream activation of the pathway and display nuclear YAP1 localization along with increased self-renewal in vitro and in vivo. The Hippo-YAP1/TAZ pathway has been argued to be dispensable in HSC, but our most recent data suggests this pathway, in conjunction with Scribble polarization, may play an essential role in regulating HSC self-renewal. Understanding this connection will allow us to exploit novel targets such as these during ex vivo HSC-based gene-therapy for successful treatment of cancers and hematologic diseases.
Molly’s thesis work is centered on oncogenic drivers of innate immune signaling in the pathogenesis of Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML). Overexpression of immune-related genes is widely reported in MDS and AML and chronic innate immune pathway activation increases the risk of developing myeloid malignancies. However, the genetic and mutational alterations that drive innate immune signaling in MDS and AML hematopoietic stem cells remain largely unknown. Molly’s findings have identified mutations in splicing factor U2AF1 that lead to alternative splicing of an innate immune signaling protein, IRAK4. Overexpression of a hyper-active isoform of IRAK4 contributes to leukemogenesis and demonstrate the first genetic link of RNA splicing factor mutations to activation of chronic innate immune signaling in leukemia. These findings have transformative implications in understanding how differential RNA isoform expression and splicing gene mutations contribute to human cancer.
The Program sincerely thanks Dr. and Mrs. Cardell for their continued support of the CCB Graduate Program and for honoring excellence in cancer and cell biological research. Bob Cardell was the former Chair of Cell Biology and the founder of the departmental graduate program. During his tenure, he built the Department into a nationally recognized research unit and later served as Associate Dean for Graduate Education. Emma Lou Cardell was an outstanding electron microscopist, histologist, and teacher. They established the Cardell Fellowship in 1999 through a gift to the UC Foundation that supports an annual award for the recipient. This year each recipient will receive $1,500 to use for professional development, and will give a special departmental seminar during the Fall semester.
Many thanks also go out to the dedicated and thoughtful members of the Selection Committee: Drs. Dave Plas (Chair), Zalfa Abdel-Malek, Chunying Du, Daniel Starczynowski, and Sonya Ruiz-Torres (student representative). In addition to reviewing the applications and selecting the recipients, the Committee has been instrumental in providing feedback on the content, form and process for the fellowship that have materially improved the Fellowship procedures.
Congratulations Madeline Niederkorn and Sonya Ruiz-Torres as the joint-recipients of the 2017 Robert and Emma Lou Cardell Fellowship.
Madeline’s (Daniel Starczynowski’s Lab) thesis work aims to uncover biological and molecular functions of TIFAB and to understand how its loss contributes to the pathogenesis of del(5q) myeloid malignancies. TIFAB is normally expressed in healthy hematopoietic cells, but is deleted by loss of chromosome 5q in myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML). Madeline’s work investigates TIFAB interactions with USP15 and p53. p53 expression and function are aberrantly active in TIFAB-deficient mice, rendering hematopoietic cells sensitive to cellular stress, and impairing hematopoietic function. Madeline’s work provides a novel molecular basis for therapeutic opportunities in del(5q) MDS and AML.
Sonya’s (Susa Wells’ Lab) work aims to determine the effect of loss of function of the Fanconi Anemia (FA) DNA repair pathway on human squamous epithelial development and carcinogenesis. Inherited mutations in FA pathway genes cause the genome instability disorder FA, wherein affected individuals have a unique susceptibility to the development of squamous cell carcinomas (SCC) of the skin, head and neck, and anogenital tissues. Sonya established a patient-derived induced pluripotent stem cell system with conditional functionality of the FA pathway as a source of epidermal stem and progenitor cells (ESPCs) to model FA pathway loss on mucosa and skin development. Results reveal proliferation and novel cell adhesion defects leading to impaired tissue integrity in the FA pathway- deficient epidermis. Moreover, her studies suggest a role for the AKT/GSK-3β/β-catenin signaling axis in driving these aberrant phenotypes, opening a door for the design of treatments for solid tumors in these patients.
The Program sincerely thanks Dr. and Mrs. Cardell for their continued support of the CCB Graduate Program and for honoring excellence in cancer and cell biological research. Bob Cardell was the former Chair of Cell Biology and the founder of the departmental graduate program. During his tenure, he built the Department into a nationally recognized research unit and later served as Associate Dean for Graduate Education. Emma Lou Cardell was an outstanding electron microscopist, histologist, and teacher. They established the Cardell Fellowship in 1999 through a gift to the UC Foundation that supports an annual cash prize for the recipient. This year each recipient will receive $1,500 to use for professional development, and will give a special Departmental seminar during the Fall semester.
Many thanks also go out to the dedicated and thoughtful members of the Selection Committee: Drs. Dave Plas (Chair), Zalfa Abdel-Malek, Chunying Du, David Hildeman, and Marie Matrka. In addition to reviewing the applications and selecting the recipients, the Committee has been instrumental in providing feedback on the content, form and process for the fellowship that have materially improved the Fellowship procedures.
Sonya and Maddie, congratulations on your hard work and impressive achievements!
Congratulations to Kris Alavattam, who was recently named an Albert J. Ryan Fellow for 2017-2018
Kris graduated from Kettering College in 2013 with a B.Sc. in Human Biology. During his undergraduate studies. he completed a Summer Undergraduate Research Fellowship at Cincinnati Children's with Dr. Satoshi Namekawa. He then joined the Namekawa laboratory as a full time research assistant in 2013. At that time, Kris' studies focused on the mechanisms of DNA damage response and epigenetic events during mammalian reproduction. These studies resulted in a co-first author publication in the Journal of Cell Biology (Broering & Alavattam et al., 2014). In that work, Kris and colleagues revealed important functions for the protein BRCA1 in male germ cell development.
Encouraged by his success, and with a growing passion for research, Kris entered the CCB Graduate Program to pursue a Ph.D.in 2014.Continuing under the mentorship of Dr. Namekawa, Kris expanded his focus to the functions of the Fanconi anemia/BRCA pathway in male germ cell development. This research led to a coauthor article that characterizes the function of FANCB in the male germline (Human Molecular Genetics; Kato et al., 2015) as well as a lead author study in Cell Reports (Alavattam et al., 2016).This work provided several mechanistic insights into the function and regulation of the Fanconi anemia/BRCA pathway, revealing new links between DNA damage response and epigenetic programming, and establishing the sex chromosomes in male germ cells as a model to dissect DNA damage response pathways. Kris has also begun to have an impact on a separate project targeted at understanding the regulation of gene expression during germ cell development. Kris seeks to define the molecular mechanisms that coordinate nuclear organization and large-scale gene expression changes in male germ cell development. This line of research has already resulted in a coauthor manuscript (Developmental Cell; Hasegawa et al., 2015) and will continue to be developed as the basis for Kris' dissertation research.
"The Albert J. Ryan Fellowship was established in 1967 by Alice M. Ryan of Cincinnati in memory of her father. Ms. Ryan wished to recognize and encourage the development of students at Dartmouth College, Harvard University. and the University of Cincinnati who show promise of becoming research scholars and who show the capacity to contribute to the advancement of medical science." - Albert J. Ryan Foundation
We would like to welcome this year's Cancer & Cell Biology Graduate Students. Camille Sullivan, Ayusman Dash, Brian Hunt, Ying Qing and James Bartram joined the program on Monday, July 11th. We are very excited for this group to start their research rotations immediately and course work in August.
Jordan Althoff (in Dr. Jose Cancelas' lab at CCHMC) who was recently named as a University of Cincinnati Albert J. Ryan Fellow. Jordan received a Bachelor degree in Biomedical Sciences from Murray State University in 2013. As an undergraduate, Jordan successfully competed to obtain funding to study a functionally redundant aminopeptidase family and its necessity for the reproductive success of Caenorhabditis elegans under the mentorship of Dr. Chris Trzepacz (University of Cincinnati College of Medicine PhD graduate and former Ryan Fellow) which culminated in a first author publication. He gained additional research experience working on molecular mechanisms that drive Acute Lymphoblastic Leukemia with Dr. Charles Mullighan at St. Jude Children's Research Hospital (Pediatric Oncology Education Program).
In the summer of 2013, Jordan joined the UC Graduate Program in Cancer and Cell Biology and is currently pursuing his PhD under the mentorship of Dr. Jose A. Cancelas at Cincinnati Children's Hospital Medical Center (CCHMC). Dr. Cancelas' research focuses on the cellular and molecular mechanisms of hematopoietic stem cell homing, migration and differentiation through Rac GTPase signaling in both health and leukemia. The laboratory is also actively investigating the physiological cell-autonomous and microenvironment/cytokine dependent mechanisms that control hematopoiesis with the hope that they can identify novel targets that can be used clinically to improve stem cell transplantation efficacy and ameliorate HSC diseases. Jordan's thesis work investigates how the bone marrow microenvironment affects various cell polarity regulators that define quiescent HSC polarization and self-renewal ability. Cell polarity is one of the most basic properties of all living cells and plays a pivotal role in HSC biology, regulating its quiescence, fate determination and function. Preliminary work from his project has secured him an NIH fellowship (F-31) from the National Heart, Lung and Blood Institute for the remainder or his training and development.
“The Albert J. Ryan Fellowship was established in 1967 by Alice M. Ryan of Cincinnati in memory of her father. Miss Ryan wished to recognize and encourage the development of students at Dartmouth College, Harvard University and the University of Cincinnati who show promise of becoming research scholars and who show the capacity to contribute to the advancement of medical science.” −Ryan Foundation.
Congratulations to Sasha Ruiz-Torres, CCB Graduate Student in Dr. Susan Waltz's lab, who has been name this year's Cardell Fellow. The Cardell Fellowship honors excellence in Cancer & Cell biological Research. Bob Cardell was Chair of Cell Biology for many years, building the Department into a nationally-recognized research unit, was the founder of the graduate program and was later Associate Dean for Graduate Education. Emma Lou Cardell was an outstanding electron microscopist, histologist and teacher. The Cardell Fellowship includes a $2,500 cash award that the recipient can use to further his/her professional development. In addition, the Fellow give a special Departmental seminar attended by the Cardell's.
Congratulations to Nick Brown, (Waltz lab) and Raghav Pandey, (Habeebahmed Lab) Cancer & Cell Biology Graduate Students, on receiving this year's University Research Council (URC) Graduate Student Research Fellowship. There were 109 applicants to this year's fellowship with only 22% of the proposals reviewed were funded. Great job Nick and Raghav for a great job in receiving this Fellowship!
The Office of Graduate Education in the College of Medicine hosted the 36th annual Graduate Student Research Forum Oct. 27, 2015. The forum brings together graduate students, postdoctoral students and faculty for a poster session, speaker and awards ceremony.
This year’s event drew 81 student poster presenters, as well as 56 faculty and postdoctoral judges to the CARE/Crawley Atrium for scientific discourse. Each student poster was scored by two different non-affiliated judges, and the scores were combined to determine the top presenters.
After the morning poster session, students and faculty enjoyed the event’s keynote speaker, Bruce McEwen, PhD, Alfred E. Mirsky Professor, the Rockefeller University. He presented the talk "Sex, Stress and the Brain: Hormone Actions over the Life Course via Novel Mechanisms.”
Graduate students in UC programs also received awards for their poster presentations.
Two first-place awards were given to Carolyn Rydyznski, immunology and Eric Smith, Cancer and Cell Biology and the MSTP Program. Second place was awarded to Nina Bertaux-Skeirik, systems biology and physiology, and third-place honors went to Marie Matrka, Cancer and Cell Biology. Four students were received honorable mentions: Vicky Gomez, molecular and developmental biology; Brittany Kopp, neuroscience; Amanda Stover, MPH in biostatistics, and Raghav Pandey, Cancer and Cell Biology.
Mark Baccei, PhD, associate professor in the Neuroscience Graduate Program, was awarded the Richard Akeson Excellence in Graduate Teaching Award.
Adam Price, a Senior at Xavier University, conducting his senior research project in the laboratory of Dr. Maria Czyzyk-Krzeska in the Department of Cancer Biology won First Prize for poster presentation at the Sixth BHD Symposium and First International Upstate Kidney Cancer Symposium that took place on September 23-26, in Syracuse, New York. The poster title is “ VHL and FLCN tumor suppressors are positive regulator of autophagic program targeting midbodies for lysosomal degradation”. The work was co-authored by Adam D. Price, Megan E. Bischoff, Emily Stepanchick, Birgit Ehmer, Johnson Chu, Jarek Meller and Maria F. Czyzyk-Krzeska.
Great kudos to G3 student Eric Smith (in Susa Well’s lab), this year’s recipient of the Robert and Emma Lou Cardell Fellowship, which honors excellence in cancer and cell biological research.
Eric’s thesis work aims to determine a mechanistic function of the DEK oncogene in DNA repair. DEK is highly overexpressed in most tumor types, and the degree of overexpression is associated with advance stage disease, poor clinical outcomes, and chemotherapy resistance. Conversely, loss of DEK restores sensitivity to DNA-damaging chemotherapeutics. However, the mechanism linking the biochemistry of the DNA-binding and chromatin modifying DEK protein to chemoresistance remains unknown. Eric’s work demonstrated that DEK loss severely cripples the homologous recombination repair pathway. Eric pinpointed the site of DEK action by determining that DEK interacts with RPA and RAD51, opening a clear avenue towards the development of therapeutic small molecule inhibitors. The Selection Committee was particularly impressed with the potential impact of these findings.
Dr. and Mrs. Cardell established the Fellowship in 1999 and it is awarded each year to an advanced student in the Cancer and Cell Biology Graduate Program. Bob Cardell was Chair of Cell Biology for many years, building the Department into a nationally-recognized research unit, and was later Associate Dean for Graduate Education. Emma Lou Cardell was an outstanding electron microscopist, histologist and teacher. The Cardell Fellowship includes a $2,500 cash award that the recipient can use to further his/her professional development. In addition, the Fellow gives a special Departmental seminar attended by the Cardells.
Eric, congratulations and thanks for your hard work and impressive achievements!
Cancer & Cell Biology Graduate Students Stand Out at 2015 GSRF Poster Forum
The Office of Graduate Education hosted its 35th annual Graduate Student Research Forum on Friday, March 6, 2015. The forum brings together graduate students, postdoctoral students and faculty for a poster session, speaker and awards ceremony. This year’s event drew 55 student poster presenters, as well as 30 faculty and postdoctoral judges, to the CARE/Crawley Atrium for lively scientific discussions.
Each graduate student poster was scored by two different non-affiliated judges, and the scores were combined to determine the top presenters. First-place award went to Rahul D’Mello, in the Medical Scientist Training Program Division of Immunology, Allergy and Rheumatology, while second-place prizes were awarded to Marie Matrka in the graduate program of Cancer and Cell Biology and Carolyn Rydyznski in the Division of Immunology, Allergy and Rheumatology. Third- place honors were awarded to Alexander Ross in the Department of Pharmacology and Cell Biophysics and Jennifer Schwanekamp in the Department of Molecular Genetics, Biochemistry and Microbiology.
Honorable mentions include: Mark Althoff and Nicholas Brown, both in the graduate program in Cancer Biology; Catherine Chaton, Swati Tiwari and Cameron McDaniel, all in the Department of Molecular Genetics, Biochemistry and Microbiology; George Gardner in the Department of Pharmacology and Cell Biophysics; and Jared Klarquist in the Division of Immunology, Allergy and Rheumatology.
Dr. Nira Ben-Jonathan Professor of Cancer Biology, talks about her recent breast cancer research on Fox 19.
An article by Jun-Lin Guan, PhD, Francis Brunning Endowed Chair and professor of cancer biology, was recently listed as on of the "Most Read Articles" in the past five days from the journal Genes and Development. Guan was senior author of the paper "p62/SQSTM1 synergizes with autophagy for tumor growth in vivo" and co-authored it with colleagues from the University of Michigan Medical School and Ohio State University Comprehensive Cancer Center.
Czyzyk-Krzeska Wins College of Medicine Planning Grant
The UC College of Medicine announces the first awardees of the College of Medicine Planning Grants. Our own Dr. Maria Czyzyk-Kreska, Professor in the Department of Cancer Biology with an affiliation at the Cincinnati Department of Veterans Affairs medical Center is one of the two recipients of this award.
Dr. Czyzyk-Krzeska was awarded $25,000 for her proposal. She will work with co-principal investigators David Hui, PhD, Professor in the Department of Pathology and Michael Borchers, PhD, Associate Professor in Internal Medicine and collaborating investigators Patrick Limbach, PhD, Chemistry and Jaroslaw Meller, PhD, Environmental Health and Cincinnati Children's Hospital Medical Center to obtain pilot data directly supporting a novel collaborative and interdisciplinary research program studying the connection between the effects of two recognized risk factors in cancer: tobacco smoking and obesity. "Molecular Mechanisms by Which Tobacco Smoke (TS) and Obesity (OB) Predispose to Cancer Development.
Susan Waltz, PhD, professor of cancer biology, has been asked to serve on the Cancer Molecular Pathology Study Section for the National Institutes of Health, for the term beginning July 1, 2014 and ending June 30, 2020.
The Cancer Molecular Pathobiology [CAMP] Study Section reviews applications involving the pathology of the malignant cell with the emphasis on mechanisms controlling cell growth and death, and the molecular events in gene regulation. Emphasis is on pathological approaches to oncogenesis and the basic cellular events involving growth of transformed cells in animal models, with more translational studies in human cells.
David Plas, PhD, associate professor of cancer biology, has accepted an invitation to serve on the Tumor Cell Biology Study Section, Center for Scientific Review at the National Institutes of Health (NIH).
Study sections review grant applications submitted to the NIH, make recommendations to the appropriate NIH national advisory council or board and survey the status of research in their fields of science.
Members are selected on the basis of their demonstrated competence and achievement in their scientific discipline as evidenced by the quality of research accomplishments, publications in scientific journals and other significant scientific activities, achievements and honors.
Program DirectorSusan Waltz, PhD
Admissions and Recruitment DirectorTom Cunningham, PhD
Vontz Center for Molecular Studies 3125 Eden AvenuePO Box 670521Cincinnati, OH 45267-0521
Mail Location: 0521Phone: 513-558-5323Fax: 513-558-1190Email: CCBProgramManager@uc.edu