Publications 

Complete list of our publications, please visit: Guo Chang Fan Publications (Pubmed)
Citations of our published work:  Guo Chang Fan Citations (Google Scholar)

2025

Du, Wa; Ringer, Madison; Huang, Wei; Desai, Darshini; Khandakar, Golam Iftakhar; Tron Esqueda, Luis; Wang, Chenran; Guan, Jun-Lin; Becker, Richard C; Sadayappan, Sakthivel; Fan, Guo-Chang; Wang, Yigang; Fan, Yanbo 2025. Endothelial Transcription Factor EB Protects Against Doxorubicin-Induced Endothelial Toxicity and Cardiac Dysfunction. Circulation, ,

Pan, Mingliang; Li, Zhixin; Wang, Xiaohong; Yang, Tianyuan; Li, Jingqi; Huang, Wei; Fan, Hongkuan; Kesten, Nebahat Ece; Peng, Tianqing; Zhan, Liying; Fan, Guo-Chang 2025. Reduced plasma levels of Copine 5 correlate with sepsis-induced vascular leakage and mortality in human patients and a murine sepsis model. Critical care (London, England), 29 1, 497

Chowdhury, Debabrata; Fan, Guo-Chang 2025. Ufmylation-Mediated Unfolded Protein Response as An Innovative Therapeutic Target in Peripartum Cardiomyopathy. JACC. Basic to translational science, 10 10, 101332

Pan, Mingliang; Li, Zhixin; Wang, Xiaohong; Zhan, Liying; Fan, Guo-Chang 2025. Noncoding RNAs in myocardial ischemia/reperfusion injury and repair. Current opinion in physiology, 44 ,

Ni, Rui; Ji, Xiao-Yun; Cao, Ting; Liu, Xiu-Wen; Wang, Chao; Lu, Chao; Peng, Angel; Zhang, Zhu-Xu; Fan, Guo-Chang; Zhang, Jin; Su, Zhao-Liang; Peng, Tian-Qing 2025. Nicotinamide mononucleotide protects septic hearts in mice via preventing cyclophilin F modification and lysosomal dysfunction. Acta pharmacologica Sinica, 46 4, 976-988

Ni, Rui; Cao, Ting; Ji, Xiaoyun; Peng, Angel; Zhang, Zhuxu; Fan, Guo-Chang; Stathopulos, Peter; Chakrabarti, Subrata; Su, Zhaoliang; Peng, Tianqing 2025. DNA damage-inducible transcript 3 positively regulates RIPK1-mediated necroptosis. Cell death and differentiation, 32 2, 306-319

2024

Wang, Xiaohong; Du, Wa; Li, Yutian; Yang, Hui-Hui; Zhang, Yu; Akbar, Rubab; Morgan, Hannah; Peng, Tianqing; Chen, Jing; Sadayappan, Sakthivel; Hu, Yueh-Chiang; Fan, Yanbo; Huang, Wei; Fan, Guo-Chang 2024. Macrophage-enriched Sectm1a promotes efficient efferocytosis to attenuate ischemia/reperfusion-induced cardiac injury. JCI insight, 9 5,

Zhu, Ruiyao; Zhang, Yu; Wang, Xiaohong; Liu, Benjamin D; Chowdhury, Debabrata; Li, Zhixin; Pan, Mingliang; Peng, Tianqing; Chen, Jing; Huang, Wei; Zhan, Liying; Fan, Guo-Chang 2024. Probiotic bacteria-released extracellular vesicles enhance macrophage phagocytosis in polymicrobial sepsis by activating the FPR1/2 pathway. Molecular medicine (Cambridge, Mass.), 30 1, 216

2023

Zhao, Hongyan; Wang, Peng; Wang, Xiaohong; Du, Wa; Yang, Hui-Hui; Liu, Yueying; Cui, Shu-Nan; Huang, Wei; Peng, Tianqing; Chen, Jing; Gao, Chen; Wang, Yigang; Sadayappan, Sakthivel; Ma, Chengen; Fan, Yanbo; Wang, Chunting; Fan, Guo-Chang 2023. Lipocalin 10 is essential for protection against inflammation-triggered vascular leakage by activating LRP2-Ssh1 signaling pathway. Cardiovascular research, ,

Wu, Zhichao; Huang, Wei; He, Xingyu; Dutta, Suchandrima; Paul, Christian; Fan, Guo-Chang; Kanisicak, Onur; Xu, Meifeng; Liang, Jialiang; Wang, Yigang 2023. Myocardial IGF2R is a critical mediator of inflammation and fibrosis after ischemia-reperfusion injury. bioRxiv : the preprint server for biology, ,

Yang, Hui-Hui; Wang, Xiaohong; Li, Siru; Liu, Yueying; Akbar, Rubab; Fan, Guo-Chang 2023. Lipocalin family proteins and their diverse roles in cardiovascular disease. Pharmacology & therapeutics, 244 , 108385

Saas, Philippe; Fan, Guo-Chang 2023. Editorial: Hypoxia and inflammation: A two-way street. Frontiers in immunology, 14 , 1171116

Feng, Yuliang; Cai, Liuyang; Pook, Martin; Liu, Feng; Chang, Chao-Hui; Mouti, Mai Abdel; Nibhani, Reshma; Wu, Shihong; Deng, Siwei; Militi, Stefania; Dunford, James; Philpott, Martin; Fan, Yanbo; Fan, Guo-Chang; Liu, Qi; Qi, Jun; Sadayappan, Sakthivel; Jegga, Anil G; Oppermann, Udo; Wang, Yigang; Huang, Wei; Jiang, Lei; Pauklin, Siim 2023. BRD9-SMAD2/3 orchestrates stemness and tumorigenesis in pancreatic ductal adenocarcinoma. bioRxiv : the preprint server for biology, ,

Ren, Lu; Du, Wa; Song, Dan; Lu, Haocheng; Hamblin, Milton H; Wang, Chenran; Du, Chunying; Fan, Guo-Chang; Becker, Richard C; Fan, Yanbo 2023. Genetic ablation of diabetes-associated gene Ccdc92 reduces obesity and insulin resistance in mice. iScience, 26 1, 105769

Liu, Benjamin D; Akbar, Rubab; Oliverio, Anna; Thapa, Kajol; Wang, Xiaohong; Fan, Guo-Chang 2023. Bacterial Extracellular Vesicles in the Regulation of Inflammatory Response and Host-Microbe Interactions. Shock (Augusta, Ga.), ,

Feng, Yuliang; Cai, Liuyang; Pook, Martin; Liu, Feng; Chang, Chao-Hui; Mouti, Mai Abdel; Nibhani, Reshma; Militi, Stefania; Dunford, James; Philpott, Martin; Fan, Yanbo; Fan, Guo-Chang; Liu, Qi; Qi, Jun; Wang, Cheng; Hong, Wanzi; Morgan, Hannah; Wang, Mingyang; Sadayappan, Sakthivel; Jegga, Anil G; Oppermann, Udo; Wang, Yigang; Huang, Wei; Jiang, Lei; Pauklin, Siim 2023. BRD9-SMAD2/3 Orchestrates Stemness and Tumorigenesis in Pancreatic Ductal Adenocarcinoma. Gastroenterology, ,

Cao, Ting; Ni, Rui; Ding, Weimin; Ji, Xiaoyun; Fan, Guo-Chang; Zhang, Zhuxu; Peng, Tianqing 2023. Nicotinamide mononucleotide as a therapeutic agent to alleviate multi-organ failure in sepsis. Journal of translational medicine, 21 1, 883

2022

Ji, Xiao-Yun; Zheng, Dong; Ni, Rui; Wang, Jin-Xi; Shao, Jian-Qiang; Vue, Zer; Hinton, Antentor; Song, Long-Sheng; Fan, Guo-Chang; Chakrabarti, Subrata; Su, Zhao-Liang; Peng, Tian-Qing 2022. Sustained over-expression of calpain-2 induces age-dependent dilated cardiomyopathy in mice through aberrant autophagy. Acta pharmacologica Sinica, 43 11, 2873-2884

Cao, Ting; Ni, Rui; Ding, Weimin; Ji, Xiaoyun; Li, Lan; Liao, Guangneng; Lu, Yanrong; Fan, Guo-Chang; Zhang, Zhuxu; Peng, Tianqing 2022. MLKL-mediated necroptosis is a target for cardiac protection in mouse models of type-1 diabetes. Cardiovascular diabetology, 21 1, 165

Li, Huili; Cao, Ting; Ding, Weimin; Liang, Liwen; Fan, Guo-Chang; Qu, Lina; Peng, Tianqing 2022. Pharmacological inhibition of Rac1 attenuates myocardial abnormalities in tail-suspended mice. Journal of cardiovascular translational research, 15 4, 805-815

Li, Qianqian; Li, Yutian; Huang, Wei; Wang, Xiaohong; Liu, Zhenling; Chen, Jing; Fan, Yanbo; Peng, Tianqing; Sadayappan, Sakthivel; Wang, Yigang; Fan, Guo-Chang 2022. Loss of Lipocalin 10 Exacerbates Diabetes-Induced Cardiomyopathy via Disruption of Nr4a1-Mediated Anti-Inflammatory Response in Macrophages. Frontiers in immunology, 13 , 930397

Feng, Yuliang; Cai, Liuyang; Hong, Wanzi; Zhang, Chunxiang; Tan, Ning; Wang, Mingyang; Wang, Cheng; Liu, Feng; Wang, Xiaohong; Ma, Jianyong; Gao, Chen; Kumar, Mohit; Mo, Yuanxi; Geng, Qingshan; Luo, Changjun; Lin, Yan; Chen, Haiyang; Wang, Shuang-Yin; Watson, Michael J; Jegga, Anil G; Pedersen, Roger A; Fu, Ji-Dong; Wang, Zhao V; Fan, Guo-Chang; Sadayappan, Sakthivel; Wang, Yigang; Pauklin, Siim; Huang, Feng; Huang, Wei; Jiang, Lei 2022. Rewiring of 3D Chromatin Topology Orchestrates Transcriptional Reprogramming and the Development of Human Dilated Cardiomyopathy. Circulation, 145 22, 1663-1683

Zhang, Mengxiao; Zhong, Huiting; Cao, Ting; Huang, Yifan; Ji, Xiaoyun; Fan, Guo-Chang; Peng, Tianqing 2022. Gamma-Aminobutyrate Transaminase Protects against Lipid Overload-Triggered Cardiac Injury in Mice. International journal of molecular sciences, 23 4,

Jiang, Lin; Liang, Jialiang; Huang, Wei; Ma, Jianyong; Park, Ki Ho; Wu, Zhichao; Chen, Peng; Zhu, Hua; Ma, Jian-Jie; Cai, Wenfeng; Paul, Christian; Niu, Liang; Fan, Guo-Chang; Wang, Hong-Sheng; Kanisicak, Onur; Xu, Meifeng; Wang, Yigang 2022. CRISPR activation of endogenous genes reprograms fibroblasts into cardiovascular progenitor cells for myocardial infarction therapy. Molecular therapy : the journal of the American Society of Gene Therapy, 30 1, 54-74