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Research Activities

The Division of General Obstetrics and Gynecology has been involved in several research projects.  The majority of our research has benefitted from our association with our subspecialty divisions (Maternal Fetal Medicine, Urogynecology and Reproductive Endocrinology and Infertility).

Our publications:


Kreinbrink, Paul J; Lewis, Luke M; Redmond, Kevin P; Takiar, Vinita 2022. Reirradiation of Recurrent and Second Primary Cancers of the Head and Neck: a Review of the Contemporary Evidence. Current treatment options in oncology, 23 3, 295-310

Korns, Julianna; Liu, Xiaoqi; Takiar, Vinita 2022. A review of Plks: Thinking outside the (polo) box. Molecular carcinogenesis, 61 2, 254-263

Dubey, Poornima; Sertorio, Mathieu; Takiar, Vinita 2022. Therapeutic Advancements in Metal and Metal Oxide Nanoparticle-Based Radiosensitization for Head and Neck Cancer Therapy. Cancers, 14 3,

Qiu, Kangqiang; Seino, Ryo; Han, Guanqun; Ishiyama, Munetaka; Ueno, Yuichiro; Tian, Zhiqi; Sun, Yujie; Diao, Jiajie 2022. De novo Design of A Membrane-anchored Probe for Multi-dimensional Quantification of Endocytic Dynamics. Advanced healthcare materials, , e2102185

Shannon, Daniel; Gruber, Weston; Lohmueller, Isaac; Hawryschuk, Ethan; Medley, Wyatt; Poetker, Gavin; Diao, JaiJie 2022. The role of FIP200 in Phagophore formation during Autophagy. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 36 Suppl 1 ,

Wang, Lei; Diao, Jiajie 2022. VAMP8 phosphorylation regulates lysosome dynamics during autophagy. Autophagy reports, 1 1, 79-82

Manupati, Kanakaraju; Paul, Ritama; Hao, Mingang; Haas, Michael; Bian, Zhaoqun Christine; Holm, Tammy M; Guan, Jun-Lin; Yeo, Syn Kok 2022. Biglycan Promotes Cancer Stem Cell Properties, NF?B Signaling and Metastatic Potential in Breast Cancer Cells. Cancers, 14 2,

Yang, Yang; Gomez, Maria; Marsh, Timothy; Poillet-Perez, Laura; Sawant, Akshada; Chen, Lei; Park, Noel R; Jackson, S RaElle; Hu, Zhixian; Alon, Noa; Liu, Chen; Debnath, Jayanta; Guan, Jun-Lin; Davidson, Shawn; Verzi, Michael; White, Eileen 2022. Autophagy in PDGFR?+ mesenchymal cells is essential for intestinal stem cell survival. Proceedings of the National Academy of Sciences of the United States of America, 119 21, e2202016119

Yang, Yi; Zhu, Yifu; Zhou, Shuai; Tang, Peipei; Xu, Ran; Zhang, Yuwei; Wei, Dongping; Wen, Jian; Thorne, Rick F; Zhang, Xu Dong; Guan, Jun-Lin; Liu, Lianxin; Wu, Mian; Chen, Song 2022. TRIM27 cooperates with STK38L to inhibit ULK1-mediated autophagy and promote tumorigenesis. The EMBO journal, , e109777

Ruiz-Torres, Sasha J; Bourn, Jennifer R; Benight, Nancy M; Hunt, Brian G; Lester, Carissa; Waltz, Susan E 2022. Macrophage-mediated RON signaling supports breast cancer growth and progression through modulation of IL-35. Oncogene, 41(3) Jan, 321-333

Hunt, Brian G; Jones, Angelle; Lester, Carissa; Davis, James C; Benight, Nancy M; Waltz, Susan E 2022. RON (MST1R) and HGFL (MST1) Co-Overexpression Supports Breast Tumorigenesis through Autocrine and Paracrine Cellular Crosstalk. Cancers, 14 10,

Muto, Tomoya; Guillamot, Maria; Yeung, Jennifer; Fang, Jing; Bennett, Joshua; Nadorp, Bettina; Lasry, Audrey; Redondo, Luna Zea; Choi, Kwangmin; Gong, Yixiao; Walker, Callum S; Hueneman, Kathleen; Bolanos, Lyndsey C; Barreyro, Laura; Lee, Lynn H; Greis, Kenneth D; Vasyliev, Nikita; Khodadadi-Jamayran, Alireza; Nudler, Evgeny; Lujambio, Amaia; Lowe, Scott W; Aifantis, Iannis; Starczynowski, Daniel T 2022. TRAF6 functions as a tumor suppressor in myeloid malignancies by directly targeting MYC oncogenic activity. Cell stem cell, ,

Crowther, Rebecca R; Schmidt, Stephanie M; Lange, Shannon M; McKell, Melanie C; Robillard, Michelle C; Zhao, Junfang; Haffey, Wendy D; Wyder, Michael A; Greis, Kenneth D; Setchell, Kenneth D R; Qualls, Joseph E 2022. Cutting Edge: l-Arginine Transfer from Antigen-Presenting Cells Sustains CD4+ T Cell Viability and Proliferation. Journal of immunology (Baltimore, Md. : 1950), 208 4, 793-798

Kirley, Terence L; Norman, Andrew B; Greis, Kenneth D 2022. Oxidation of specific tryptophan residues inhibits high affinity binding of cocaine and its metabolites to a humanized anti-cocaine mAb. The Journal of biological chemistry, , 101689

Barreyro, Laura; Sampson, Avery M; Ishikawa, Chiharu; Hueneman, Kathleen M; Choi, Kwangmin; Pujato, Mario A; Chutipongtanate, Somchai; Wyder, Michael; Haffey, Wendy D; O'Brien, Eric; Wunderlich, Mark; Ramesh, Vighnesh; Kolb, Ellen M; Meydan, Cem; Neelamraju, Yaseswini; Bolanos, Lyndsey C; Christie, Susanne; Smith, Molly A; Niederkorn, Madeline; Muto, Tomoya; Kesari, Santosh; Garrett-Bakelman, Francine E; Bartholdy, Boris; Will, Britta; Weirauch, Matthew T; Mulloy, James C; Gul, Zartash; Medlin, Stephen; Kovall, Rhett A; Melnick, Ari M; Perentesis, John P; Greis, Kenneth D; Nurmemmedov, Elmar; Seibel, William L; Starczynowski, Daniel T 2022. Blocking UBE2N abrogates oncogenic immune signaling in acute myeloid leukemia. Science translational medicine, 14 635, eabb7695

Kirley, Terence L; Greis, Kenneth D; Norman, Andrew B 2022. Tyrosine nitration of a humanized anti-cocaine mAb differentially affects ligand binding of cocaine and its metabolites. Biochemistry and biophysics reports, 30 , 101278

Blaha, Catherine S; Ramakrishnan, Gopalakrishnan; Jeon, Sang-Min; Nogueira, Veronique; Rho, Hyunsoo; Kang, Soeun; Bhaskar, Prashanth; Terry, Alexander R; Aissa, Alexandre F; Frolov, Maxim V; Patra, Krushna C; Brooks Robey, R; Hay, Nissim 2022. A non-catalytic scaffolding activity of hexokinase 2 contributes to EMT and metastasis. Nature communications, 13 1, 899

Yan, Ling; Xu, Xiaoxiao; Fan, Yanbo; Zhang, Lifang; Niu, Xiaojing; Hu, Aimin 2022. Tangshen Decoction Enhances Podocytes Autophagy to Relieve Diabetic Nephropathy through Modulation of p-AMPK/p-ULK1 Signaling. Evidence-based complementary and alternative medicine : eCAM, 2022 , 3110854


Lewis, Luke; Kreinbrink, Paul; Richardson, Max; Westerfield, Morgan; Doberstein, Madeline; Zhang, Yongbin; Redmond, Kevin; Takiar, Vinita 2021. Intensity Modulated Proton Therapy Better Spares Non-Adjacent Organs and Reduces the Risk of Secondary Malignant Neoplasms in the Treatment of Sinonasal Cancers. Medical dosimetry : official journal of the American Association of Medical Dosimetrists, ,

Hernandez Brandi, Marianna; Howell, Rebecca; Power, Amelia; Tabangin, Meredith; Altaye, Mekibib; Zender, Chad A; Takiar, Vinita; Tang, Alice L 2021. Trends in Number of Women Speakers at the American Head and Neck Society Meetings, 2007-2019. JAMA otolaryngology-- head & neck surgery, 147 12, 1053-1058

Luginbuhl, Adam; Calder, Alyssa; Kutler, David; Zender, Chad; Wise-Draper, Trisha; Patel, Jena; Cheng, Michael; Karivedu, Vidhya; Zhan, Tingting; Parashar, Bhupesh; Gulati, Shuchi; Yao, Min; Lavertu, Pierre; Takiar, Vinita; Tang, Alice; Johnson, Jennifer; Keane, William; Curry, Joseph; Cognetti, David; Bar-Ad, Voichita 2021. Multi-Institutional Study Validates Safety of Intraoperative Cesium-131 Brachytherapy for Treatment of Recurrent Head and Neck Cancer. Frontiers in oncology, 11 , 786216

Kreinbrink, Paul J; Mierzwa, Michelle L; Huth, Brad; Redmond, Kevin P; Wise-Draper, Trisha M; Casper, Keith; Li, Junan; Takiar, Vinita 2021. Adjuvant radiation and cetuximab improves local control in head and neck cutaneous squamous cell carcinoma: Phase II study. Head & neck, 43 11, 3408-3416

von Allmen, Douglas; Tang, Alice; Takiar, Vinita; Zender, Chad; Romeo, Stephen; Masch, Jessica; Casper, Keith; Patil, Yash; Wilson, Keith; Khosla, Siddarth; Niu, Liang; Altaye, Mekibib; Tabangin, Meredith; Howell, Rebecca J 2021. Modified Head and Neck Swallow Scale: Using EORTC-QLQ-H&N35 to Predict Overall Survival. The Laryngoscope, 131 11, 2478-2482

Frankart, Andrew J; Takiar, Vinita 2021. In Reply to Laurent et al. International journal of radiation oncology, biology, physics, 111 2, 584

Sharma, Anish; Tang, Alice L; Takiar, Vinita; Wise-Draper, Trisha M; Langevin, Scott M 2021. Human Papillomavirus and Survival of Sinonasal Squamous Cell Carcinoma Patients: A Systematic Review and Meta-Analysis. Cancers, 13 15,

Leddon, Jennifer L; Chirra, Martina; Frankart, Andrew J; Agrawal, Arushi; Roof, Logan; Trotier, Danny; Shaikh, Hira; Stone, Timothy; Jandarov, Roman; Takiar, Vinita; Wise-Draper, Trisha M 2021. Hypothyroidism in Head and Neck Squamous Cell Carcinoma Patients Receiving Radiotherapy With or Without Immune Checkpoint Inhibitors. The Laryngoscope, 131 7, E2413-E2419

Takiar, Vinita 2021. In Reference to The Psychological Impact of Head and Neck Cancer in Pain Perception. The Laryngoscope, 131 6, E1911

Kreinbrink, P J; Li, J; Parajuli, S; Wise-Draper, T M; Choi, D L; Tang, A L; Takiar, V 2021. Pre-treatment absolute lymphocyte count predicts for improved survival in human papillomavirus (HPV)-driven oropharyngeal squamous cell carcinoma. Oral oncology, 116 , 105245

Wicker, Christina A; Hunt, Brian G; Krishnan, Sunil; Aziz, Kathryn; Parajuli, Shobha; Palackdharry, Sarah; Elaban, William R; Wise-Draper, Trisha M; Mills, Gordon B; Waltz, Susan E; Takiar, Vinita 2021. Glutaminase inhibition with telaglenastat (CB-839) improves treatment response in combination with ionizing radiation in head and neck squamous cell carcinoma models. Cancer letters, 502 , 180-188

Frankart, Andrew J; Criss, Benjamin E; Dillehay McKillip, Kelsey; Wise-Draper, Trisha; Takiar, Vinita; Kharofa, Jordan 2021. Assessing the Reliability and Positive Predictive Value of p16 as a Surrogate for Human Papillomavirus-Mediated E6/7 mRNA Expression in Squamous Cell Carcinoma of the Anal Canal. Diseases of the colon and rectum, 64 4, 459-465

Frankart, Andrew J; Frankart, Michael J; Cervenka, Brian; Tang, Alice L; Krishnan, Deepak G; Takiar, Vinita 2021. Osteoradionecrosis: Exposing the Evidence Not the Bone. International journal of radiation oncology, biology, physics, 109 5, 1206-1218

Wilke, Christopher; Takiar, Vinita; Wang, He; Moreno, Amy C; Tung, Shih-Ming Samuel; Quinlan-Davidson, Sean R; Garden, Adam S; Rosenthal, David I; Fuller, Clifton D; Gunn, Gary B; Reddy, Jay P; Morrison, William H; Wang, Congjun; Zhao, George; Hutcheson, Katherine A; Phan, Jack 2021. Defining the dose-volume criteria for laryngeal sparing in locally advanced oropharyngeal cancer utilizing split-field IMRT, whole-field IMRT and VMAT. Journal of applied clinical medical physics, 22 1, 37-44

Zheng, Xiaoqiang; Yan, Jin; You, Weiming; Li, Fanni; Diao, Jiajie; He, Wangxiao; Yao, Yu 2021. De Novo Nano-Erythrocyte Structurally Braced by Biomimetic Au(I)-peptide Skeleton for MDM2/MDMX Predation toward Augmented Pulmonary Adenocarcinoma Immunotherapy. Small (Weinheim an der Bergstrasse, Germany), , e2100394

Lerner, Eitan; Barth, Anders; Hendrix, Jelle; Ambrose, Benjamin; Birkedal, Victoria; Blanchard, Scott C; Börner, Richard; Sung Chung, Hoi; Cordes, Thorben; Craggs, Timothy D; Deniz, Ashok A; Diao, Jiajie; Fei, Jingyi; Gonzalez, Ruben L; Gopich, Irina V; Ha, Taekjip; Hanke, Christian A; Haran, Gilad; Hatzakis, Nikos S; Hohng, Sungchul; Hong, Seok-Cheol; Hugel, Thorsten; Ingargiola, Antonino; Joo, Chirlmin; Kapanidis, Achillefs N; Kim, Harold D; Laurence, Ted; Lee, Nam Ki; Lee, Tae-Hee; Lemke, Edward A; Margeat, Emmanuel; Michaelis, Jens; Michalet, Xavier; Myong, Sua; Nettels, Daniel; Peulen, Thomas-Otavio; Ploetz, Evelyn; Razvag, Yair; Robb, Nicole C; Schuler, Benjamin; Soleimaninejad, Hamid; Tang, Chun; Vafabakhsh, Reza; Lamb, Don C; Seidel, Claus Am; Weiss, Shimon 2021. FRET-based dynamic structural biology: Challenges, perspectives and an appeal for open-science practices. eLife, 10 ,

Tao, Youqi; Xie, Jingfei; Zhong, Qinglu; Wang, Yongyao; Zhang, Shengnan; Luo, Feng; Wen, Fengcai; Xie, Jingjing; Zhao, Jiawei; Sun, Xiaoou; Long, Houfang; Ma, Junfeng; Zhang, Qian; Long, Jiangang; Fang, Xianyang; Lu, Ying; Li, Dan; Li, Ming; Zhu, Jidong; Sun, Bo; Li, Guohui; Diao, Jiajie; Liu, Cong 2021. A novel partially-open state of SHP2 points to a "multiple gear" regulation mechanism. The Journal of biological chemistry, , 100538

Fang, Hongbao; Geng, Shanshan; Hao, Mingang; Chen, Qixin; Liu, Minglun; Liu, Chunyan; Tian, Zhiqi; Wang, Chengjun; Takebe, Takanori; Guan, Jun-Lin; Chen, Yuncong; Guo, Zijian; He, Weijiang; Diao, Jiajie 2021. Simultaneous Zn2+ tracking in multiple organelles using super-resolution morphology-correlated organelle identification in living cells. Nature communications, 12 1, 109

Zou, Weiwei; Chen, Qixin; Slone, Jesse; Yang, Li; Lou, Xiaoting; Diao, Jiajie; Huang, Taosheng 2021. Nanoscopic quantification of sub-mitochondrial morphology, mitophagy and mitochondrial dynamics in living cells derived from patients with mitochondrial diseases. Journal of nanobiotechnology, 19 1, 136

Chen, Qixin; Hao, Mingang; Wang, Lei; Li, Linsen; Chen, Yang; Shao, Xintian; Tian, Zhiqi; Pfuetzner, Richard A; Zhong, Qing; Brunger, Axel T; Guan, Jun-Lin; Diao, Jiajie 2021. Prefused lysosomes cluster on autophagosomes regulated by VAMP8. Cell death & disease, 12 10, 939

Yan, Jin; Wang, Yang; Li, Xiao; Guo, Dongnan; Zhou, Zhengjun; Bai, Ge; Li, Jianhui; Huang, Na; Diao, Jiajie; Li, Yong; He, Wangxiao; Liu, Wenjia; Tao, Kaishan 2021. A Bionic Nano-Band-Aid Constructed by the Three-Stage Self-Assembly of Peptides for Rapid Liver Hemostasis. Nano letters, 21 17, 7166-7174

Wang, Kang-Nan; Shao, Xintian; Tian, Zhiqi; Liu, Liu-Yi; Zhang, Chengying; Tan, Cai-Ping; Zhang, Jie; Ling, Peixue; Liu, Fei; Chen, Qixin; Diao, Jiajie; Mao, Zong-Wan 2021. A Continuous Add-On Probe Reveals the Nonlinear Enlargement of Mitochondria in Light-Activated Oncosis. Advanced science (Weinheim, Baden-Wurttemberg, Germany), 8 17, e2004566

Du, Yang; Lai, Ying; Liu, Ji-Yan; Diao, Jiajie 2021. Epigenetic Quantification of DNA 5-Hydroxymethylcytosine Using DNA Hybridization-Based Single-Molecule Immunofluorescent Imaging. Small methods, 5 5, e2100061

Aryal, Chinta Mani; Tyoe, Owen; Diao, Jiajie 2021. Lipid Species Dependent Vesicles Clustering Caused by alpha-Synuclein as Revealed by Single-Vesicle Imaging with Total Internal Reflection Fluorescence Microscopy. Biophysics reports, 7 6, 437-448

Terasawa, Kazue; Kato, Yuji; Ikami, Yuta; Sakamoto, Kensaku; Ohtake, Kazumasa; Kusano, Seisuke; Tomabechi, Yuri; Kukimoto-Niino, Mutsuko; Shirouzu, Mikako; Guan, Jun-Lin; Kobayashi, Toshihide; Iwata, Takanori; Watabe, Tetsuro; Yokoyama, Shigeyuki; Hara-Yokoyama, Miki 2021. Direct homophilic interaction of LAMP2A with the two-domain architecture revealed by site-directed photo-crosslinks and steric hindrances in mammalian cells. Autophagy, , 1-19

Hao, Mingang; Yeo, Syn Kok; Guan, Jun-Lin 2021. Autophagy inhibition perturbs ERBB2 trafficking and abolishes tumorigenesis in ERBB2-driven breast cancer. Autophagy, 17 4, 1059-1060

Wang, Chenran; Haas, Michael A; Yeo, Syn Kok; Paul, Ritama; Yang, Fuchun; Vallabhapurapu, Subrahmanya; Qi, Xiaoyang; Plas, David R; Guan, Jun-Lin 2021. Autophagy mediated lipid catabolism facilitates glioma progression to overcome bioenergetic crisis. British journal of cancer, 124 , 1711–1723

Yang, Yongguang; Leonard, Marissa; Luo, Zhenhua; Yeo, Syn; Bick, Gregory; Hao, Mingang; Cai, Chunmiao; Charif, Mahmoud; Wang, Jiang; Guan, Jun-Lin; Lower, Elyse E; Zhang, Xiaoting 2021. Functional cooperation between co-amplified genes promotes aggressive phenotypes of HER2-positive breast cancer. Cell reports, 34 10, 108822

Hao, Mingang; Yeo, Syn Kok; Turner, Kevin; Harold, Alexis; Yang, Yongguang; Zhang, Xiaoting; Guan, Jun-Lin 2021. Autophagy Blockade Limits HER2+ Breast Cancer Tumorigenesis by Perturbing HER2 Trafficking and Promoting Release Via Small Extracellular Vesicles. Developmental cell, 56 3, 341-355.e5

Bischoff, Megan E; Zang, Yuanwei; Chu, Johnson; Price, Adam D; Ehmer, Birgit; Talbot, Nicholas J; Newbold, Michael J; Paul, Anurag; Guan, Jun-Lin; Plas, David R; Meller, Jarek; Czyzyk-Krzeska, Maria F 2021. Selective MAP1LC3C (LC3C) autophagy requires noncanonical regulators and the C-terminal peptide. The Journal of cell biology, 220 7,

Yi, Fei; Zhang, Ying; Wang, Zhijun; Wang, Zhuo; Li, Ziwei; Zhou, Tingting; Xu, Hongde; Liu, Jingwei; Jiang, Bo; Li, Xiaoman; Wang, Liang; Bai, Ning; Guo, Qiqiang; Guan, Yi; Feng, Yanling; Mao, Zhiyong; Fan, Guangjian; Zhang, Shengping; Wang, Chuangui; Cao, Longyue; O'Rourke, Brian P; Wang, Yang; Wu, Yanmei; Wu, Boquan; You, Shilong; Zhang, Naijin; Guan, Junlin; Song, Xiaoyu; Sun, Yingxian; Wei, Shi; Cao, Liu 2021. The deacetylation-phosphorylation regulation of SIRT2-SMC1A axis as a mechanism of antimitotic catastrophe in early tumorigenesis. Science advances, 7 9,

Wang, Chenran; Haas, Michael; Yeo, Syn Kok; Sebti, Salwa; Fernández, Álvaro F; Zou, Zhongju; Levine, Beth; Guan, Jun-Lin 2021. Enhanced autophagy in Becn1F121A/F121A knockin mice counteracts aging-related neural stem cell exhaustion and dysfunction. Autophagy, , 1-14

Turner, Kevin M; Yeo, Syn Kok; Holm, Tammy M; Shaughnessy, Elizabeth; Guan, Jun-Lin 2021. Heterogeneity Within Molecular Subtypes of Breast Cancer. American journal of physiology. Cell physiology, ,

Wang, Lingyan; Song, Kun; Hao, Wenzhuo; Wu, Yakun; Patil, Girish; Hua, Fang; Sun, Yiwen; Huang, Chaoqun; Ritchey, Jerry; Jones, Clinton; Liu, Lin; Guan, Jun-Lin; Li, Shitao 2021. FIP200 restricts RNA virus infection by facilitating RIG-I activation. Communications biology, 4 1, 921

Holm, Tammy M; Bian, Z Christine; Manupati, Kanakaraju; Guan, Jun-Lin 2021. Inhibition of autophagy mitigates cell migration and invasion in thyroid cancer. Surgery, ,

Liu, Hang; Wang, Chenran; Yi, Fei; Yeo, Syn; Haas, Michael; Tang, Xin; Guan, Jun-Lin 2021. Non-canonical function of FIP200 is required for neural stem cell maintenance and differentiation by limiting TBK1 activation and p62 aggregate formation. Scientific reports, 11 1, 23907

Poillet-Perez, Laura; Sharp, Daniel W; Yang, Yang; Laddha, Saurabh V; Ibrahim, Maria; Bommareddy, Praveen K; Hu, Zhixian Sherrie; Vieth, Joshua; Haas, Michael; Bosenberg, Marcus W; Rabinowitz, Joshua D; Cao, Jian; Guan, Jun-Lin; Ganesan, Shridar; Chan, Chang S; Mehnert, Janice M; Lattime, Edmund C; White, Eileen 2021. Publisher Correction: Autophagy promotes growth of tumors with high mutational burden by inhibiting a T-cell immune response. Nature cancer, 2 9, 994

Czyzyk-Krzeska, Maria F; Landero Figueroa, Julio A; Gulati, Shuchi; Cunningham, John T; Meller, Jarek; ShamsaeI, Behrouz; Vemuri, Bhargav; Plas, David R 2021. Molecular and Metabolic Subtypes in Sporadic and Inherited Clear Cell Renal Cell Carcinoma. Genes, 12 3,

Czyzyk-Krzeska, Maria F; Meller, Jarek; Landero Figueroa, Julio A; Plas, David R; Cunningham, John T 2021. Metabolic subtypes of clear cell renal cell carcinoma defined by tobacco smoking. Molecular & cellular oncology, 8 2, 1859917

Reigle, James; Secic, Dina; Biesiada, Jacek; Wetzel, Collin; Shamsaei, Behrouz; Chu, Johnson; Zang, Yuanwei; Zhang, Xiang; Talbot, Nicholas J; Bischoff, Megan E; Zhang, Yongzhen; Thakar, Charuhas V; Gaitonde, Krishnanath; Sidana, Abhinav; Bui, Hai; Cunningham, John T; Zhang, Qing; Schmidt, Laura S; Linehan, W Marston; Medvedovic, Mario; Plas, David R; Figueroa, Julio A Landero; Meller, Jarek; Czyzyk-Krzeska, Maria F 2021. Tobacco smoking induces metabolic reprogramming of renal cell carcinoma. The Journal of clinical investigation, 131 1,

Tang, Xin; Angst, Gabrielle; Haas, Michael; Yang, Fuchun; Wang, Chenran 2021. The Characterization of a Subependymal Giant Astrocytoma-Like Cell Line from Murine Astrocyte with mTORC1 Hyperactivation. International journal of molecular sciences, 22 8,

Bourn, Jennifer R; Ruiz-Torres, Sasha J; Hunt, Brian G; Benight, Nancy M; Waltz, Susan E 2021. Tumor cell intrinsic RON signaling suppresses innate immune responses in breast cancer through inhibition of IRAK4 signaling. Cancer letters, 503 , 75-90

Vilfranc, Chrystelle L; Che, Li-Xiao; Patra, Krushna C; Niu, Liang; Olowokure, Olugbenga; Wang, Jiang; Shah, Shimul A; Du, Chun-Ying 2021. BIR repeat-containing ubiquitin conjugating enzyme (BRUCE) regulation of ?-catenin signaling in the progression of drug-induced hepatic fibrosis and carcinogenesis. World journal of hepatology, 13 3, 343-361

Cai, Chunmiao; Bi, Dexi; Bick, Gregory; Wei, Qing; Liu, Hu; Lu, Ling; Zhang, Xiaoting; Qin, Huanlong 2021. Hepatocyte nuclear factor HNF1A is a potential regulator in shaping the super-enhancer landscape in colorectal cancer liver metastasis. FEBS letters, ,

Zhao, Guizhen; Chang, Ziyi; Zhao, Yang; Guo, Yanhong; Lu, Haocheng; Liang, Wenying; Rom, Oren; Wang, Huilun; Sun, Jinjian; Zhu, Tianqing; Fan, Yanbo; Chang, Lin; Yang, Bo; Garcia-Barrio, Minerva T; Chen, Y Eugene; Zhang, Jifeng 2021. KLF11 protects against abdominal aortic aneurysm through inhibition of endothelial cell dysfunction. JCI insight, 6 5,

Liu, Yuhao; Zhao, Ying; Shukha, Yousef; Lu, Haocheng; Wang, Lu; Liu, Zhipeng; Liu, Cai; Zhao, Yang; Wang, Huilun; Zhao, Guizhen; Liang, Wenying; Fan, Yanbo; Chang, Lin; Yurdagul, Arif; Pattillo, Christopher B; Orr, A Wayne; Aviram, Michael; Wen, Bo; Garcia-Barrio, Minerva T; Zhang, Jifeng; Liu, Wanqing; Sun, Duxin; Hayek, Tony; Chen, Y Eugene; Rom, Oren 2021. Dysregulated oxalate metabolism is a driver and therapeutic target in atherosclerosis. Cell reports, 36 4, 109420

Lu, Haocheng; Sun, Jinjian; Hamblin, Milton H; Chen, Y Eugene; Fan, Yanbo 2021. Transcription factor EB regulates cardiovascular homeostasis. EBioMedicine, 63 , 103207

Du, Wa; Ren, Lu; Hamblin, Milton H; Fan, Yanbo 2021. Endothelial Cell Glucose Metabolism and Angiogenesis. Biomedicines, 9 2,

Lu, Haocheng; Du, Wa; Ren, Lu; Hamblin, Milton H; Becker, Richard C; Chen, Y Eugene; Fan, Yanbo 2021. Vascular Smooth Muscle Cells in Aortic Aneurysm: From Genetics to Mechanisms. Journal of the American Heart Association, , e023601

Fan, Yanbo; Wolford, Brooke N; Lu, Haocheng; Liang, Wenying; Sun, Jinjian; Zhou, Wei; Rom, Oren; Mahajan, Anubha; Surakka, Ida; Graham, Sarah E; Liu, Zhipeng; Kim, Hyunbae; Ramdas, Shweta; Fritsche, Lars G; Nielsen, Jonas B; Gabrielsen, Maiken Elvestad; Hveem, Kristian; Yang, Dongshan; Song, Jun; Garcia-Barrio, Minerva T; Zhang, Jifeng; Liu, Wanqing; Zhang, Kezhong; Willer, Cristen J; Chen, Y Eugene 2021. Type 2 diabetes sex-specific effects associated with E167K coding variant in TM6SF2. iScience, 24 11, 103196

Liang, Wenying; Lu, Haocheng; Sun, Jinjian; Zhao, Guizhen; Wang, Huilun; Guo, Yanhong; Eitzman, Daniel; Chen, Y Eugene; Fan, Yanbo; Zhang, Jifeng 2021. KLF11 Protects against Venous Thrombosis via Suppressing Tissue Factor Expression. Thrombosis and haemostasis, ,

Qing, Ying; Dong, Lei; Gao, Lei; Li, Chenying; Li, Yangchan; Han, Li; Prince, Emily; Tan, Brandon; Deng, Xiaolan; Wetzel, Collin; Shen, Chao; Gao, Min; Chen, Zhenhua; Li, Wei; Zhang, Bin; Braas, Daniel; Ten Hoeve, Johanna; Sanchez, Gerardo Javier; Chen, Huiying; Chan, Lai N; Chen, Chun-Wei; Ann, David; Jiang, Lei; Müschen, Markus; Marcucci, Guido; Plas, David R; Li, Zejuan; Su, Rui; Chen, Jianjun 2021. R-2-hydroxyglutarate attenuates aerobic glycolysis in leukemia by targeting the FTO/m6A/PFKP/LDHB axis. Molecular cell, 81 5, 922-939.e9

Koehler, Abigail; Karve, Aniruddha; Desai, Pankaj; Arbiser, Jack; Plas, David R; Qi, Xiaoyang; Read, Renee D; Sasaki, Atsuo T; Gawali, Vaibhavkumar S; Toukam, Donatien K; Bhattacharya, Debanjan; Kallay, Laura; Pomeranz Krummel, Daniel A; Sengupta, Soma 2021. Reuse of Molecules for Glioblastoma Therapy. Pharmaceuticals (Basel, Switzerland), 14 2,


Hunt, Brian G; Wicker, Christina A; Bourn, Jennifer R; Lower, Elyse E; Takiar, Vinita; Waltz, Susan E 2020. MST1R (RON) expression is a novel prognostic biomarker for metastatic progression in breast cancer patients. Breast cancer research and treatment, ,

Havard, Molly; Esslinger, Hope; Mierzwa, Michelle; Kharofa, Jordan; Takiar, Vinita 2020. Increased Pain Reporting by Head and Neck Cancer Patients at Radiation Oncology Consultation: A Quality-of-Life Analysis. The Laryngoscope, ,

Venkatraman, Anumitha; Kaval, Farah; Takiar, Vinita 2020. Body Mass Index and Age Affect Maximum Mouth Opening in a Contemporary American Population. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, ,

Wicker, Christina A; Takiar, Vinita; Suganya, Rangaswamy; Arnold, Susanne M; Brill, Yolanda M; Chen, Li; Horbinski, Craig M; Napier, Dana; Valentino, Joseph; Kudrimoti, Mahesh R; Yu, Guoqiang; Izumi, Tadahide 2020. Evaluation of antioxidant network proteins as novel prognostic biomarkers for head and neck cancer patients. Oral oncology, 111 , 104949

Lewis, Luke M; Tang, Alice L; Wise-Draper, Trisha M; Myers, Kasiani C; Greenberger, Joel S; Takiar, Vinita 2020. Successful use of a therapeutic trial of graduated volume and dose escalation for postoperative head and neck radiotherapy in a Fanconi anemia patient. Head & neck, 42 10, E16-E22

Khanna, Suchin; Palackdharry, Sarah; Roof, Logan; Wicker, Christina A; Mark, Jonathan; Zhu, Zheng; Jandorav, Roman; Molinolo, Alfredo; Takiar, Vinita; Wise-Draper, Trisha M 2020. Determining the molecular landscape and impact on prognosis in HPV-associated head and neck cancer. Cancers of the head & neck, 5 , 11

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