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Inaugural CASB

Inaugural Cryo-EM Symposium presented by CASB (Center for Advanced Structural Biology)

The University of Cincinnati is celebrating the opening of the Cryo-EM center in association with CASB. The celebration will take place on Friday, September 8, 2023 at the Graduate Hotel on the University of Cincinnati East/Medical campus in order to commemorate the acquisition and installation of two Cryo-EM microscopes – Talos L120c and Glacios. The all-day symposium will feature two Keynote Speakers – Dr. Stephen Blacklow from Harvard Medical School and Dr. Chris Lima from Memorial Sloan Kettering – as well as talks from other local and regional structural biologists. The day’s schedule will include coffee breaks, catered lunch, and an evening reception with a trainee poster session with light refreshments and appetizers. We welcome anyone interested in learning more about the Cryo-EM capabilities of CASB to attend the free symposium. Generous sponsorship is provided by Herman Lichstein Endowment and through a gift from Drs. Judith Heiny and Piotr Chomczynski. We look forward to celebrating the Cryo-EM center and kickstarting this new structural biology initiative as part of Research2030 – UC’s 10-year strategic research plan.

Keynote/Lichstein Lecturers


Stephen C. Blacklow, MD, PhD

Stephen C. Blacklow, MD, PhD is the Gustavus Adolphus Pfeiffer Professor and Chair of the Department of Biological Chemistry and Molecular Pharmacology at Harvard Medical School, and a member of the Department of Cancer Biology at the Dana Farber Cancer Institute.

View More About Stephen C. Blacklow

Photo of Christopher D. LimaChristopher D. Lima, PhD

Christopher D. Lima, PhD is a Howard Hughes Medical Institute Investigator at the Sloan Kettering Institute in New York City where he is Chair and Member of the Structural Biology Program. He holds an Alfred P. Sloan endowed chair and is a Professor in the Weill Cornell and Sloan Kettering Graduate Schools.

View More About Christopher D. Lima

The Lichstein lecturers are possible via “Endowed by a grant from Jerome Birnbaum & Merck Sharp & Dohme Research Laboratories, Division of Merck & Co., Inc., Rahway, New Jersey.”

View More About Dr. Lichstein



8:30am – 9:00am

  • Check-in, coffee and continental breakfast
  • Location: North Pre-function Space

9:00am – 9:45am

  • Welcome, introductions by Dr. Ken Greis, Dr. Patrick Limbach, Dr. Desiree Benefield, Jane Combs
  • Location: Cincinnatus Ballroom

9:45am – 10:45am

  • Keynote Speaker: Stephen C. Blacklow, MD, PhD, Harvard Medical School presents "Structural Plasticity in Signaling"
  • Location: Cincinnatus Ballroom

10:45am – 11:00am

  • Coffee Break – vendor tables on display
  • Location: North Pre-function Area

11:00am – 11:30am

  • Tom Seegar, PhD, University of Cincinnati presents “Structure and Regulation of Ectodomain Sheddases in Development and Disease”
  • Location: Cincinnatus Ballroom

11:30am – 12:00pm

  • Carrie Shaffer, PhD, University of Kentucky presents “Structure-function analyses reveal novel DNA substrate selection mechanisms in the H. pylori cag T4SS nanomachine”
  • Location: Cincinnatus Ballroom

12:00pm – 1:00pm

  • Lunch
  • Location: Fountain Square Room


1:00pm – 1:30pm

  • Xiaowei Hou, PhD, University of Cincinnati “Crystal and cryo-EM structures reveal insights into CRAC channel activation“
  • Location: Cincinnatus Ballroom

1:30pm – 2:00pm

  • Andrew Herr, PhD, CCHMC, presents “Structural studies of host attachment and intercellular adhesion by a multifunctional staphylococcal biofilm protein”
  • Location: Cincinnatus Ballroom

2:00pm – 2:30pm

  • Rick Page, PhD, Miami University, presents “The coupling of folding status to protein quality control outcomes”
  • Location: Cincinnatus Ballroom

2:30pm – 3:00pm

  • Coffee Break
  • Location: North Pre-function Area

3:00pm – 3:30pm

  • Student Poster Flash-Talks
  • Location: Cincinnatus Ballroom

3:30pm – 4:30pm

  • Keynote Speaker: Christopher Lima, PhD, Sloan Kettering Institute presents "Structural transitions in the ubiquitin conjugation cascade"
  • Location: Cincinnatus Ballroom

4:30pm – 6:00pm

  • Grand Opening Reception and Poster Session
  • Location: CVC Atrium


Photo of UC Graduate Hotel

Graduate Hotel
151 Goodman Dr, Cincinnati, OH 45219

Parking will be available at Kingsgate Garage (under Graduate Hotel) & Eden Avenue Garage

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