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Our laboratory is interested in ion channels and the membrane mechanisms that regulate the activation and function of human lymphocytes. Ion channels control calcium homeostasis and downstream associated effector functions. The main interests of the lab
span from studying the function and regulation of ion channel in normal lymphocytes to determining ion channel abnormalities in cancer and autoimmunity.
We integrate a multidisciplinary approach in collaboration with clinicians and basic research scientists. The techniques used in the laboratory include, but are not limited to, electrophysiology (patch-clamp), flow cytometry, and fluorescence and confocal
microscopy. Furthermore, nanotechnology methods are currently applied with the goal of developing novel therapeutic agents. Our translational approach offers an exciting environment for trainees to learn more about human disease biology and
therapeutic advances in the treatment of cancer and autoimmunity.
Dr. Conforti is presently a member/collaborator of several departments at the UC College of Medicine, Engineering and Children’s Hospital.
Department of Internal Medicine, Div. of Nephrology & Hypertension Department of Pharmacology & Systems Physiology (Adjunct)
Department of Molecular Genetics, Biochemistry & Microbiology (Affiliate)
Pathobiology and Molecular medicine Graduate Program (Mentor)
T32 Training Program in Cancer Therapeutics (Mentor)
Department of Pediatrics, Division of Immunobiology (Collaborator)
Medical Sciences Building Room 6065231 Albert Sabin WayPO Box 670557Cincinnati, OH 45267-0557
Phone: 513-558-4231Fax: 513-558-0852Email: email@example.com