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Publications

For the most up-to-date list, please find our publications via ORCIDPubMed, or Google Scholar.

Last updated 21 May 2021

Peer-Reviewed Publications

 

  1. Adam D. Maxwell, Kevin J. Haworth, Christy K. Holland, Samuel A. Hendley, Wayne Keider, Kenneth, B. Bader. (accepted). Design and Characterization of an Ultrasound Transducer for Combined Histotripsy-Thrombolytic Therapy. IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control.

  2. Samuel A. Hendley, Jonathan D. Paul, Adam D. Maxwell, Kevin J. Haworth, Christy K. Holland, Kenneth, B. Bader. (accepted). Clot degradation under the action of histotripsy bubble activity and a lytic drug. IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control doi: 10.1109/TUFFC.2021.3052393

  3. Maxime Lafond, Nuria G. Salido, Kevin J. Haworth, Alexander S. Hannah, Curtis Genstler, Christy K. Holland. (2021). Cavitation emissions Nucleated by Definity(R) Infused Through an EkoSonic(R) Catheter in a Flow Phantom. Ultrasound in Medicine and Biology. 47(3):693-709 doi: 10.1016/j.ultrasmedbio.2020.10.010

  4. Patrick H. Kee, Melanie R. Moody, Shao-Ling Huang, Hyunggun Kim, Xing Yin, Tao Peng, Susan T. Laing, Melvin E. Klegerman, Mohammad H. Rahbar, Deborah Vela, Curtis Genstler, Kevin J. Haworth, Christy K. Holland, David D. McPherson. (accepted) “Stabilizing peri- stent restenosis using a novel therapeutic carrier.” JACC: Basic to Translational Science.

  5. Viktor Bollen, Samuel A. Hendley, Jonathan D. Paul, Adam D. Maxwell, Kevin J. Haworth, Christy K. Holland, Kenneth B. Bader. (2020) “In vitro thrombolytic efficacy of single- and five-cycle histotripsy pulses and rt-PA.” Ultrasound in Medicine and Biology. 46(2):336-349 doi: 10.1016/j.ultrasmedbio.2019.10.009

  6. Robert Kleven, Himanshu Shekhar, Kunal Karani, Nuria Salido, T. Douglas Mast, Kevin J. Haworth, Christy K. Holland. (2019) “The effect of 220 kHz insonation scheme on rt-PA thrombolytic efficacy in vitro.” Physics in Medicine and Biology. 64(16):165015(1-17) doi: 10.1088/1361-6560/ab293b

  7. Karla P. Mercado-Shekhar, Haili Su, Deepak S. Kalaikadal, John N. Lorenz, Raj M. Manglik, Christy K. Holland, Andrew N. Redington, Kevin J. Haworth. (2019) “Acoustic droplet vaporization-mediated dissolved oxygen scavenging in blood-mimicking fluids, plasma, and blood.” Ultrasonics Sonochemistry. 56:114-124 doi: 10.1016/j.ultsonch.2019.03.029

  8. Himanshu Shekhar, Pala Arunkumar, Tao Peng, Melanie R. Moody, Kevin J. Haworth, Shaoling Huang, David D. McPherson, Christy K. Holland. (2019) “Lipid-shelled microbubbles for ultrasound-triggered release of xenon.” Neurotherapeutics. doi: 10.1007/s13311-019-00733-4

  9. Khoi Nguyen, Hsuan-Yeh Pan, Kevin J. Haworth, Eric Mahoney, Karla P. Mercado-Shekhar, Chia-Ying Lin, Zhe Zhang, Yoonjee Park. (2019) “Drug Release from Stable Nanodroplets by High-Intensity Focused Ultrasound for a Potential Degenerative Disc Disease Treatment.” Ultrasound in Medicine and Biology. 45(1):160-169 doi: 10.1016/j.ultrasmedbio.2018.09.014

  10. Karla P. Mercado-Shekhar, Robert Kleven, Hermes Aponte Rivera, Ryden Lewis, Kunal B. Karani, Hendrick J. Vos, Todd A. Abruzzo, Kevin J. Haworth, Christy K. Holland. (2018) “The Effect of Clot Stiffness on rt-PA Lytic Susceptibility In Vitro.” Ultrasound in Medicine and Biology. 44(12):2710-2727 doi: 10.1016/j.ultrasmedbio.2018.08.005 

  11. Kenneth B. Bader, Kevin J. Haworth, Adam D. Maxwell, and Christy K. Holland. (2018). Post Hoc Analysis of Passive Cavitation Imaging for Classification of Histotripsy-induced Liq- uefaction In Vitro. IEEE Medical Imaging. 37(1):106-115 doi: 10.1109/TMI.2017.2735238

  12. Kevin J. Haworth, Kenneth B. Bader, Kyle T. Rich, Christy K. Holland, T. Douglas Mast. (2017). Quantitative Frequency-Domain Passive Cavitation Imaging. IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. 64(1):177-191 doi: 10.1109/TUFFC.2016.2620492

  13. Mark J. Schulz, Guangfeng Hou, Vianessa Ng, Massoud Rabiee, Marc Cahay, Sumeet Chaud- hary, Dustin Lindley, Devika Chauhan, Michael Paine, Dineshwaran Vijayakumar, Chenhao Xu, Zhangzhang Yin, Kevin J. Haworth, Yijun Liu, Murali Sundaram, Weifeng Li, David Mast, Vesselin N. Shanov. (2017). Science to commercialization of carbon nanotube sheet and yarn. WSEAS Transactions on Applied and Theoretical Mechanics. 12:41-50.

  14. Jonathan T. Sutton, Kevin J. Haworth, Shiva Kumar Shanmukhappa, Melanie R. Moody, Melvin R. Klegerman, Joseph K. Griffin, Daniella M. Patton, David D. McPherson, Christy K. Holland. (2016). Delivery of bevacizumab to atheromatous porcine carotid tissue using echogenic liposomes. Drug Delivery. 23(9):3594-3605 doi: 10.1080/10717544.2016.1212441

  15. Kenneth B. Bader, Kevin J. Haworth, Himanshu Shekhar, Adam Maxwell, Tao Peng, David D. McPherson, Christy K. Holland. (2016). Efficacy of histotripsy combined with rt-PA in vitro. Physics in Medicine and Biology. 61(14):5253-5274 doi: 10.1088/0031-9155/61/14/5253

  16. Karla P. Mercado, Kirthi Radhakrishnan, Kyle Stewart, Lindsay Snider, Devin Ryan, Kevin J. Haworth. (2016). Empirical model for size isolating ultrasound-triggered phase-shift emulsions using differential centrifugation. Journal of the Acoustical Society of America - Express Letters. 135(5):EL142-148 doi: 10.1121/1.4946831

  17. Kirthi Radhakrishnan, Christy K. Holland, Kevin J. Haworth. (2016). Scavenging dissolved oxygen via acoustic droplet vaporization. Ultrasonics Sonochemistry. 31:394-403 doi: 10.1016/j.ultsonch.2016.01.019

  18. Kevin J. Haworth, Jason L. Raymond, Kirthi Radhakrishnan, Melanie R. Moody, Shaoling Huang, Tao Peng, Himanshu Shekhar, Melvin E. Klegerman, Hyunggun Kim, David D. McPherson, and Christy K. Holland. (2016). Trans-stent B-mode ultrasound and passive cav- itation imaging. Ultrasound in Medicine and Biology. 42(2):518-527 doi: 10.1016/j.ultrasmedbio.2015.08.014

  19. Melvin E. Klegerman, Ali K. Naji, Kevin J. Haworth, Yuejiao Zou, Eva Golunski, Tao Peng, George L. Britton, Shao-Ling Huang, Christy K. Holland, David D. McPherson. (2016). Ultrasound-enhanced bevacizumab release from echogenic liposomes for inhibition of atheroma progression. Journal of Liposome Research. 26(1):47-56 doi: 10.3109/08982104.2015.1029494

  20. Kevin J. Haworth, Vasant A. Salgaonkar, Nicholas M. Corregan, Christy K. Holland, T. Douglas Mast. (2015). Using passive cavitation images to classify high-intensity focused ultrasound lesions. Ultrasound in Medicine and Biology. 41(9):2420-2434 doi: 10.1016/j.ultrasmedbio.2015.04.025

  21. Kevin J. Haworth, Christopher R. Weidner, Todd A. Abruzzo, Jason T. Shearn, Christy K. Holland. (2015). Mechanical properties and fibrin characteristics of endovascular coil- clot complexes: Relevance to endovascular cerebral aneurysm repair paradigms. Journal of NeuroInterventional Surgery. 7(4):291-296 doi: 10.1136/neurintsurg-2013-011076

  22. Kirthi Radhakrishnan, Kevin J. Haworth, Shao-Ling Huang, David D. McPherson, Christy K. Holland. (2015). Loss of echogenicity and onset of cavitation from echogenic liposomes: Pulse repetition frequency independence. Ultrasound in Medicine and Biology. 41(1):208-221 doi: 10.1016/j.ultrasmedbio.2014.08.021

  23. Jason L. Raymond, Kevin J. Haworth, Kenneth B. Bader, Kirthi Radhakrishnan, Joseph K. Griffin, Shao-Ling Huang, David D. McPherson, Christy K. Holland. (2014). Broadband attenuation measurements of phospholipid-shelled ultrasound contrast agents. Ultrasound in Medicine and Biology. 40(2):410-421 doi: 10.1016/j.ultrasmedbio.2013.09.018

  24. Kirthi Radhakrishnan, Kenneth B. Bader, Kevin J. Haworth, Jonathan A. Kopechek, Jason L. Raymond, Bin Huang, Shao-Ling Huang, David D. McPherson, Christy K. Holland. (2013). Relationship between cavitation and loss of echogenicity from ultrasound contrast agents.Physics in Medicine and Biology. 58(18):6541-6563 doi: 10.1088/0031-9155/58/18/6541

  25. Sheryl E. Koch, Kevin J. Haworth, Nathan Robbins, Margaret A. Smith, Navneet Lather, Ahmad Anjak, Min Jiang, Priyanka Varma, W. Keith Jones, and Jack Rubinstein. (2013). Age and gender related changes in myocardial function in wild type FVB/N mice as evaluated by conventional and vector velocity echocardiography imaging. Ultrasound in Medicine and Biology. 39(11):2034-2043 doi: 10.1016/j.ultrasmedbio.2013.04.002

  26. Jonathan T. Sutton, Kevin J. Haworth, Gail J. Pyne-Geithman, Christy K. Holland. (2013). Ultrasound-mediated drug delivery for cardiovascular disease. Expert Opinions on Drug De- livery. 10(5):573-592 doi: 10.1517/17425247.2013.772578

  27. Jonathan A. Kopechek, Kevin J. Haworth, Kirthi Radhakrishnan, Shao-Ling Huang, Melvin E. Klegerman, David D. McPherson, Christy K. Holland. (2013). The impact of microbub- bles on measurement of drug release from echogenic liposomes. UItrasonics Sonochemistry. 20(4):1121-1130 doi: 10.1016/j.ultsonch.2012.12.005

  28. Robert Littleton, Kevin J. Haworth, Hong Tang, Kenneth Setchell, Sandra Nelson, Jay Hove. (2013). Automated in vivo platform for the discovery of functional food treatments of hypercholesterolemia in zebrafish. PLoS ONE. 8(1):e52409 1-9 doi: 10.1371/journal.pone.0052409

  29. Kirthi Radhakrishnan, Kevin J. Haworth, Shao-Ling Huang, Melvin E. Klegerman, David D. McPherson, Christy K. Holland. (2012). Stability of echogenic liposomes as a blood pool ultrasound contrast agent in a physiologic flow phantom. Ultrasound in Medicine and Biology. 38(11):1970-1981 doi: 10.1016/j.ultrasmedbio.2012.06.012

  30. Kevin J. Haworth, T. Douglas Mast, Kirthi Radhakrishnan, Mark T. Burgess, Jonathan A. Kopechek, Shao-Ling Huang, David D. McPherson, Christy K. Holland. (2012). Passive imaging with pulsed ultrasound insonations. Journal of the Acoustical Society of America. 132(1):544-553 doi: 10.1121/1.4728230

  31. Jonathan A. Kopechek, Kevin J. Haworth, Jason L. Raymond, T. Douglas Mast, Stephen R. Perrin Jr., Melvin E. Klegerman, Shao-Ling Huang, Tyrone M. Porter, David D. McPherson, Christy K. Holland. (2011). Acoustic characterization of echogenic liposomes: frequency- dependent attenuation and backscatter. Journal of the Acoustical Society of America. 130(5, Pt. 2):3472-3481 doi: 10.1121/1.3626124

  32. Man Zhang, Mario L. Fabiilli, Kevin J. Haworth, Frederic R. Padilla, Scott D. Swanson, Oliver D. Kripfgans, Paul L. Carson, J. Brian Fowlkes. (2011). Acoustic droplet vaporization for enhancement of thermal ablation by high intensity focused ultrasound. Academic Radiology. 18(9):1123-1132 doi: 10.1016/j.acra.2011.04.012

  33. Kathryn E. Hitchcock, Nikolas M. Ivancevich, Kevin J. Haworth, Danielle N. Caudell, Deborah C. Vela, Jonathan T. Sutton, Gail J. Pyne-Geithman, Christy K. Holland. (2011). Ultrasound-enhanced rt-PA thrombolysis in an ex vivo porcine carotid artery model. Ultra- sound in Medicine and Biology. 37(8):1240-1251, doi: 10.1016/j.ultrasmedbio.2011.05.011

  34. Man Zhang, Mario L. Fabiilli, Kevin J. Haworth, J. Brian Fowlkes, Oliver D. Kripfgans, William W. Roberts, Kimberly A. Ives, Paul L. Carson. (2010). Initial investigation of acoustic droplet vaporization for occlusion in canine kidney. Ultrasound in Medicine and Biology. 36(10):1691-1703, doi: 10.1016/j.ultrasmedbio.2010.06.020

  35. Mario L. Fabiilli, Kevin J. Haworth, Ian E. Sebastian, Oliver D. Kripfgans, Paul L. Carson, J. Brian Fowlkes. (2010). Delivery of chlorambucil using acoustically-triggered, perfluoropen- tane emulsions. Ultrasound in Medicine and Biology. 36(8):1364-1375, doi: 10.1016/j.ultrasmedbio.2010.04.019

  36. Kevin J. Haworth, J. Brian Fowlkes, Paul L. Carson, Oliver D. Kripfgans. (2009). Gen- eralized shot noise model for time-reversal in multiple-scattering media allowing for arbitrary inputs and windowing. Journal of the Acoustical Society of America. 125(5):3129-3140, doi: 10.1121/1.3106133

  37. Mario L. Fabiilli, Kevin J. Haworth, Oliver D. Kripfgans, Paul L. Carson, J. Brian Fowlkes. (2009). The role of inertial cavitation in acoustic droplet vaporization. IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. 56(5):1006-1017, doi: 10.1109/TUFFC.2009.1132

  38. Kevin J. Haworth, J. Brian Fowlkes, Paul L. Carson, Oliver D. Kripfgans. (2008). Towards aberration correction of transcranial ultrasound using acoustic droplet vaporization.Ultrasound in Medicine and Biology. 34(3):435-445, doi: 10.1016/j.ultrasmedbio.2007.08.004

Proceedings Articles

  1. Kevin J. Haworth, Bryan H. Goldstein, Karla P. Mercado-Shekhar, Rohan Srivastava, P. Arunkumar, Haili Su, Ellena M. Privitera, Christy K. Holland, Andrew N. Redington. (2017). Dissolved Oxygen Scavenging by Acoustic Droplet Vaporization using Intravascular Ultra- sound. 2017 IEEE International Ultrasonics Symposium Proceedings. 1:1-4 doi: 10.1109/ULT- SYM.2017.8091704
  2. Kevin J. Haworth, Vasant A. Salgaonkar, Nicholas M. Corregan, Christy K. Holland, T. Douglas Mast. (2013). Spatial specificity and sensitivity of passive cavitation imaging for monitoring high-intensity focused ultrasound thermal ablation in ex vivo bovine liver. Proceedings of Meetings on Acoustics. 19:075022 doi: 10.1121/1.4800327
  3. Kevin J. Haworth, Oliver D. Kripfgans. (2008). Initial Growth of Ultrasonically Vaporized Perfluorocarbon Microdroplets. 2008 IEEE International Ultrasonics Symposium Proceedings. 1:623-626
  4. Kevin J. Haworth, Mario L. Fabiilli, J. Brian Fowlkes, Man Zhang, Oliver D. Kripfgans, William W. Roberts, Paul L. Carson. (2008). Mean Echo Power as a Measure of Flow Reduction for Bubble Occlusion Therapy. 2008 IEEE International Ultrasonics Symposium Proceedings. 1:768-771
  5. Mario L. Fabiilli, Kevin J. Haworth, Oliver D. Kripfgans, Paul L. Carson, J. Brian Fowlkes. (2008). The Role of Inertial Cavitation in Acoustic Droplet Vaporization. 2008 IEEE Inter- national Ultrasonics Symposium Proceedings. 1:776-779 

 

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