Skip to main content
Photo of Pankaj Desai, PhD

Pankaj Desai, PhD

Professor (F2)

Chair of Pharmaceutical Sciences Division
Professor

Contact Information
Research Interests

Pharmacokinetics and pharmacodynamics of anticancer drugs, inter-individual and inter-species variation in drug metabolism, drug delivery systems

Peer Reviewed Publications

Illamola, Sílvia M; Bhongsatiern, Jiraganya Jj; Birnbaum, Angela K; Kumar, Shaun S; Courter, Joshua D; Haslam, David B; Allegaert, Karel; Reith, David M; Desai, Pankaj B; Sherwin, Catherine M 2025. Vancomycin dosing in neonates: enhancing outcomes using population pharmacokinetics and simulation. Frontiers in antibiotics, 4 , 1568931

Mersich, Ian; Congrove, Sunny; Horchar, Matthew; Caceres, Roman; Muraleedharan, Ranjithmenon; Desai, Janki; Desai, Pankaj; Sallans, Larry; Reisz, Julie A; Grier, Abby; Hass, Matthew R; Donmez, Omer; Yin, Cailing; Weirauch, Matthew T; Kottyan, Leah; Stevenson, Charles B; Sun, Claire; de Blank, Peter; Pillay-Smiley, Natasha; Hummel, Trent R; Elumalai, Nagarajan; Tavassoli, Ali; Firestein, Ron; Phoenix, Timothy N; D'Alessandro, Angelo; Dasgupta, Biplab 2025. Integrative Multi-Omics Analysis Identifies Nuclear Factor I as a Key Driver of Dysregulated Purine Metabolism in DIPG. bioRxiv : the preprint server for biology, ,

Bhattacharya, Debanjan; Barrile, Riccardo; Toukam, Donatien Kamdem; Gawali, Vaibhavkumar S; Kallay, Laura; Ahmed, Taukir; Brown, Hawley; Rezvanian, Sepideh; Karve, Aniruddha; Desai, Pankaj B; Medvedovic, Mario; Wang, Kyle; Ionascu, Dan; Harun, Nusrat; Vallabhapurapu, Subrahmanya; Wang, Chenran; Qi, Xiaoyang; Baschnagel, Andrew M; Kritzer, Joshua A; Cook, James M; Pomeranz Krummel, Daniel A; Sengupta, Soma 2024. GABA(A) Receptor Activation Drives GABARAP-Nix Mediated Autophagy to Radiation-Sensitize Primary and Brain-Metastatic Lung Adenocarcinoma Tumors. Cancers, 16 18,

Desai, Pankaj B; Karve, Aniruddha S; Zawit, Misam; Arora, Priyanka; Dave, Nimita; Awosika, Joy; Li, Ningjing; Fuhrman, Bethany; Medvedovic, Mario; Sallans, Larry; Kendler, Ady; DasGupta, Biplab; Plas, David; Curry, Richard; Zuccarello, Mario; Chaudhary, Rekha; Sengupta, Soma; Wise-Draper, Trisha M 2024. A Phase 0/I Pharmacokinetic and Pharmacodynamics and Safety and Tolerability Study of Letrozole in Combination with Standard Therapy in Recurrent High-Grade Gliomas. Clinical cancer research : an official journal of the American Association for Cancer Research, 30 10, 2068-2077

Harlan, Sarah Schuman; Philpott, Carolyn D; Keegan, Shaun P; Droege, Molly E; Karve, Aniruddha S; Foreman, Brandon; Wakefield, Devin; Mueller, Eric W; Sangha, Kiranpal; Ngwenya, Laura B; Courter, Joshua D; Desai, Pankaj; Droege, Christopher 2024. Pharmacokinetics of Levetiracetam Seizure Prophylaxis in Severe Traumatic Brain Injury. The Annals of pharmacotherapy, 58 7, 705-714

Karve, Aniruddha S; Desai, Janki M; Gadgil, Sidharth N; Dave, Nimita; Wise-Draper, Trisha M; Gudelsky, Gary A; Phoenix, Timothy N; DasGupta, Biplab; Yogendran, Lalanthica; Sengupta, Soma; Plas, David R; Desai, Pankaj B 2024. A Review of Approaches to Potentiate the Activity of Temozolomide against Glioblastoma to Overcome Resistance. International journal of molecular sciences, 25 6,

Oatman, Nicole; Gawali, Mruniya V; Congrove, Sunny; Cáceres, Román; Sukumaran, Abitha; Gupta, Nishtha; Murugesan, Narmadha; Arora, Priyanka; Subramanian, Srividhya; Choi, Kwangmin; Abdel-Malek, Zalfa; Reisz, Julie A; Stephenson, Daniel; Amaravadi, Ravi; Desai, Pankaj; D'Alessandro, Angelo; Komurov, Kakajan; Dasgupta, Biplab 2024. A Multimodal Drug-Diet-Immunotherapy Combination Restrains Melanoma Progression and Metastasis. Cancer research, 84 14, 2333-2351

Bhattacharya, Debanjan; Barille, Riccardo; Toukam, Donatien Kamdem; Gawali, Vaibhavkumar S; Kallay, Laura; Ahmed, Taukir; Brown, Hawley; Rezvanian, Sepideh; Karve, Aniruddha; Desai, Pankaj B; Medvedovic, Mario; Wang, Kyle; Ionascu, Dan; Harun, Nusrat; Wang, Chenran; Baschnagel, Andrew M; Kritzer, Joshua A; Cook, James M; Pomeranz Krummel, Daniel A; Sengupta, Soma 2023. GABA(A) receptor activation drives GABARAP-Nix mediated autophagy to radiation-sensitize primary and brain-metastatic lung adenocarcinoma tumors. bioRxiv : the preprint server for biology, ,

Desai, Janki M; Karve, Aniruddha S; Gudelsky, Gary A; Gawali, Mruniya V; Seibel, William; Sallans, Larry; DasGupta, Biplab; Desai, Pankaj B 2022. Brain pharmacokinetics and metabolism of the AMP-activated protein kinase selective inhibitor SBI-0206965, an investigational agent for the treatment of glioblastoma. Investigational new drugs, 40 5, 944-952

Karve, Aniruddha S; Desai, Janki M; Dave, Nimita; Wise-Draper, Trisha M; Gudelsky, Gary A; Phoenix, Timothy N; DasGupta, Biplab; Sengupta, Soma; Plas, David R; Desai, Pankaj B 2022. Potentiation of temozolomide activity against glioblastoma cells by aromatase inhibitor letrozole. Cancer chemotherapy and pharmacology, 90 4, 345-356

Arora, Priyanka; Gudelsky, Gary; Desai, Pankaj B 2021. Gender-based differences in brain and plasma pharmacokinetics of letrozole in sprague-dawley rats: Application of physiologically-based pharmacokinetic modeling to gain quantitative insights. PloS one, 16 4, e0248579

Koehler, Abigail; Karve, Aniruddha; Desai, Pankaj; Arbiser, Jack; Plas, David R; Qi, Xiaoyang; Read, Renee D; Sasaki, Atsuo T; Gawali, Vaibhavkumar S; Toukam, Donatien K; Bhattacharya, Debanjan; Kallay, Laura; Pomeranz Krummel, Daniel A; Sengupta, Soma 2021. Reuse of Molecules for Glioblastoma Therapy. Pharmaceuticals (Basel, Switzerland), 14 2,

Mishra, Rosalin; Yuan, Long; Patel, Hima; Karve, Aniruddha S; Zhu, Haizhou; White, Aaron; Alanazi, Samar; Desai, Pankaj; Merino, Edward J; Garrett, Joan T 2021. Phosphoinositide 3-Kinase (PI3K) Reactive Oxygen Species (ROS)-Activated Prodrug in Combination with Anthracycline Impairs PI3K Signaling, Increases DNA Damage Response and Reduces Breast Cancer Cell Growth. International journal of molecular sciences, 22 4,

Oatman, Nicole; Dasgupta, Nupur; Arora, Priyanka; Choi, Kwangmin; Gawali, Mruniya V; Gupta, Nishtha; Parameswaran, Sreeja; Salomone, Joseph; Reisz, Julie A; Lawler, Sean; Furnari, Frank; Brennan, Cameron; Wu, Jianqiang; Sallans, Larry; Gudelsky, Gary; Desai, Pankaj; Gebelein, Brian; Weirauch, Matthew T; D'Alessandro, Angelo; Komurov, Kakajan; Dasgupta, Biplab 2021. Mechanisms of stearoyl CoA desaturase inhibitor sensitivity and acquired resistance in cancer. Science advances, 7 7,

Davis, Harold W; Vallabhapurapu, Subrahmanya D; Chu, Zhengtao; Wyder, Michael A; Greis, Kenneth D; Fannin, Venette; Sun, Ying; Desai, Pankaj B; Pak, Koon Y; Gray, Brian D; Qi, Xiaoyang 2020. Biotherapy of Brain Tumors with Phosphatidylserine-Targeted Radioiodinated SapC-DOPS Nanovesicles. Cells, 9 9,

Gulati, Shuchi; Desai, Janki; Palackdharry, Sarah M; Morris, John C; Zhu, Zheng; Jandarov, Roman; Riaz, Muhammad K; Takiar, Vinita; Mierzwa, Michelle; Gutkind, J Silvio; Molinolo, Alfredo; Desai, Pankaj B; Sadraei, Nooshin Hashemi; Wise-Draper, Trisha M 2020. Phase 1 dose-finding study of metformin in combination with concurrent cisplatin and radiotherapy in patients with locally advanced head and neck squamous cell cancer. Cancer, 126 2, 354-362

Arora, Priyanka; Adams, Courtney Huff; Gudelsky, Gary; DasGupta, Biplab; Desai, Pankaj B 2019. Plasma and brain pharmacokinetics of letrozole and drug interaction studies with temozolomide in NOD-scid gamma mice and sprague dawley rats. Cancer chemotherapy and pharmacology, 83 1, 81-89

Ananthula, Hari Krishna; Parker, Scott; Touchette, Erin; Buller, R Mark; Patel, Gopi; Kalman, Daniel; Salzer, Johanna S; Gallardo-Romero, Nadia; Olson, Victoria; Damon, Inger K; Moir-Savitz, Tessa; Sallans, Larry; Werner, Milton H; Sherwin, Catherine M; Desai, Pankaj B 2018. Preclinical pharmacokinetic evaluation to facilitate repurposing of tyrosine kinase inhibitors nilotinib and imatinib as antiviral agents. BMC pharmacology & toxicology, 19 1, 80

Lazzarini, Cristina; Haranahalli, Krupanandan; Rieger, Robert; Ananthula, Hari Krishna; Desai, Pankaj B; Ashbaugh, Alan; Linke, Michael J; Cushion, Melanie T; Ruzsicska, Bela; Haley, John; Ojima, Iwao; Del Poeta, Maurizio 2018. Acylhydrazones as Antifungal Agents Targeting the Synthesis of Fungal Sphingolipids. Antimicrobial agents and chemotherapy, 62 5,

Mehta, Rajiv; Kabrawala, Mayank; Nandwani, Subhash; Desai, Pankaj; Bhayani, Vishwa; Patel, Sanjay; Parekh, Viral 2018. Safety and Efficacy of Sofosbuvir and Daclatasvir for Hepatitis C Virus Infection in Patients with β-Thalassemia Major. Journal of clinical and experimental hepatology, 8 1, 3-6

Mor, Visesato; Rella, Antonella; Farnoud, Amir M; Singh, Ashutosh; Munshi, Mansa; Bryan, Arielle; Naseem, Shamoon; Konopka, James B; Ojima, Iwao; Bullesbach, Erika; Ashbaugh, Alan; Linke, Michael J; Cushion, Melanie; Collins, Margaret; Ananthula, Hari Krishna; Sallans, Larry; Desai, Pankaj B; Wiederhold, Nathan P; Fothergill, Annette W; Kirkpatrick, William R; Patterson, Thomas; Wong, Lai Hong; Sinha, Sunita; Giaever, Guri; Nislow, Corey; Flaherty, Patrick; Pan, Xuewen; Cesar, Gabriele Vargas; de Melo Tavares, Patricia; Frases, Susana; Miranda, Kildare; Rodrigues, Marcio L; Luberto, Chiara; Nimrichter, Leonardo; Del Poeta, Maurizio 2018. Erratum for Mor et al., "Identification of a New Class of Antifungals Targeting the Synthesis of Fungal Sphingolipids". mBio, 9 2,

Wise-Draper, Trisha M; Moorthy, Ganesh; Salkeni, Mohamad A; Karim, Nagla Abdel; Thomas, Hala Elnakat; Mercer, Carol A; Beg, M Shalaan; O'Gara, Sue; Olowokure, Olugbenga; Fathallah, Hassana; Kozma, Sara C; Thomas, George; Rixe, Olivier; Desai, Pankaj; Morris, John C 2017. A Phase Ib Study of the Dual PI3K/mTOR Inhibitor Dactolisib (BEZ235) Combined with Everolimus in Patients with Advanced Solid Malignancies. Targeted oncology, 12 3, 323-332

Bhongsatiern, Jiraganya; Stockmann, Chris; Yu, Tian; Constance, Jonathan E; Moorthy, Ganesh; Spigarelli, Michael G; Desai, Pankaj B; Sherwin, Catherine M T 2016. Renal Function Descriptors in Neonates: Which Creatinine-Based Formula Best Describes Vancomycin Clearance? Journal of clinical pharmacology, 56 5, 528-40

Bhongsatiern, Jiraganya; Stockmann, Chris; Roberts, Jessica K; Yu, Tian; Korgenski, Kent E; Spigarelli, Michael G; Desai, Pankaj B; Sherwin, Catherine M T 2015. Evaluation of Vancomycin Use in Late-Onset Neonatal Sepsis Using the Area Under the Concentration-Time Curve to the Minimum Inhibitory Concentration ≥400 Target. Therapeutic drug monitoring, 37 6, 756-65

Dave, Nimita; Chow, Lionel M L; Gudelsky, Gary A; LaSance, Kathleen; Qi, Xiaoyang; Desai, Pankaj B 2015. Preclinical pharmacological evaluation of letrozole as a novel treatment for gliomas. Molecular cancer therapeutics, 14 4, 857-64

Moorthy, Ganesh; Sallee, Floyd; Gabbita, Prasad; Zemlan, Frank; Sallans, Larry; Desai, Pankaj B 2015. Safety, tolerability and pharmacokinetics of 2-pyridylacetic acid, a major metabolite of betahistine, in a phase 1 dose escalation study in subjects with ADHD. Biopharmaceutics & drug disposition, 36 7, 429-39

Mor, Visesato; Rella, Antonella; Farnoud, Amir M; Singh, Ashutosh; Munshi, Mansa; Bryan, Arielle; Naseem, Shamoon; Konopka, James B; Ojima, Iwao; Bullesbach, Erika; Ashbaugh, Alan; Linke, Michael J; Cushion, Melanie; Collins, Margaret; Ananthula, Hari Krishna; Sallans, Larry; Desai, Pankaj B; Wiederhold, Nathan P; Fothergill, Annette W; Kirkpatrick, William R; Patterson, Thomas; Wong, Lai Hong; Sinha, Sunita; Giaever, Guri; Nislow, Corey; Flaherty, Patrick; Pan, Xuewen; Cesar, Gabriele Vargas; de Melo Tavares, Patricia; Frases, Susana; Miranda, Kildare; Rodrigues, Marcio L; Luberto, Chiara; Nimrichter, Leonardo; Del Poeta, Maurizio 2015. Identification of a New Class of Antifungals Targeting the Synthesis of Fungal Sphingolipids. mBio, 6 3, e00647

Krishan, Mansi; Gudelsky, Gary A; Desai, Pankaj B; Genter, Mary Beth 2014. Manipulation of olfactory tight junctions using papaverine to enhance intranasal delivery of gemcitabine to the brain. Drug delivery, 21 1, 8-16

Dave, Nimita; Gudelsky, Gary A; Desai, Pankaj B 2013. The pharmacokinetics of letrozole in brain and brain tumor in rats with orthotopically implanted C6 glioma, assessed using intracerebral microdialysis. Cancer chemotherapy and pharmacology, 72 2, 349-57

Mu, Chaofeng; Dave, Nimita; Hu, Jing; Desai, Pankaj; Pauletti, Giovanni; Bai, Shuhua; Hao, Jiukuan 2013. Solubilization of flurbiprofen into aptamer-modified PEG-PLA micelles for targeted delivery to brain-derived endothelial cells in vitro. Journal of microencapsulation, 30 7, 701-8

Tong, Jenny; Dave, Nimita; Mugundu, Ganesh M; Davis, Harold W; Gaylinn, Bruce D; Thorner, Michael O; Tschöp, Matthias H; D'Alessio, David; Desai, Pankaj B 2013. The pharmacokinetics of acyl, des-acyl, and total ghrelin in healthy human subjects. European journal of endocrinology, 168 6, 821-8

Liu, Li; Mugundu, Ganesh M; Kirby, Brian J; Samineni, Divya; Desai, Pankaj B; Unadkat, Jashvant D 2012. Quantification of human hepatocyte cytochrome P450 enzymes and transporters induced by HIV protease inhibitors using newly validated LC-MS/MS cocktail assays and RT-PCR. Biopharmaceutics & drug disposition, 33 4, 207-17

Mugundu, Ganesh M; Sallans, Larry; Guo, Yingying; Shaughnessy, Elizabeth A; Desai, Pankaj B 2012. Assessment of the impact of CYP3A polymorphisms on the formation of α-hydroxytamoxifen and N-desmethyltamoxifen in human liver microsomes. Drug metabolism and disposition: the biological fate of chemicals, 40 2, 389-96

Samineni, Divya; Desai, Pankaj B; Sallans, Larry; Fichtenbaum, Carl J 2012. Steady-state pharmacokinetic interactions of darunavir/ritonavir with lipid-lowering agent rosuvastatin. Journal of clinical pharmacology, 52 6, 922-31

He, Bing; Tang, Jie; Ding, Ying; Wang, Huijun; Sun, Yuyin; Shin, Jae Hong; Chen, Bin; Moorthy, Ganesh; Qiu, Judy; Desai, Pankaj; Wild, David J 2011. Mining relational paths in integrated biomedical data. PloS one, 6 12, e27506

Jackson, Richard L; Greiwe, Jeffrey S; Desai, Pankaj B; Schwen, Richard J 2011. Single-dose and steady-state pharmacokinetic studies of S-equol, a potent nonhormonal, estrogen receptor β-agonist being developed for the treatment of menopausal symptoms. Menopause (New York, N.Y.), 18 2, 185-93

Kirby, Brian J; Collier, Ann C; Kharasch, Evan D; Dixit, Vaishali; Desai, Pankaj; Whittington, Dale; Thummel, Kenneth E; Unadkat, Jashvant D 2011. Complex drug interactions of HIV protease inhibitors 2: in vivo induction and in vitro to in vivo correlation of induction of cytochrome P450 1A2, 2B6, and 2C9 by ritonavir or nelfinavir. Drug metabolism and disposition: the biological fate of chemicals, 39 12, 2329-37

Mugundu, Ganesh M; Hariparsad, Niresh; Desai, Pankaj B 2010. Impact of ritonavir, atazanavir and their combination on the CYP3A4 induction potential of efavirenz in primary human hepatocytes. Drug metabolism letters, 4 1, 45-50

Apparaju, Sandhya Kiran; Gudelsky, Gary A; Desai, Pankaj B 2008. Pharmacokinetics of gemcitabine in tumor and non-tumor extracellular fluid of brain: an in vivo assessment in rats employing intracerebral microdialysis. Cancer chemotherapy and pharmacology, 61 2, 223-9

Gupta, Anshul; Mugundu, Ganesh M; Desai, Pankaj B; Thummel, Kenneth E; Unadkat, Jashvant D 2008. Intestinal human colon adenocarcinoma cell line LS180 is an excellent model to study pregnane X receptor, but not constitutive androstane receptor, mediated CYP3A4 and multidrug resistance transporter 1 induction: studies with anti-human immunodeficiency virus protease inhibitors. Drug metabolism and disposition: the biological fate of chemicals, 36 6, 1172-80

Sane, Rucha S; Buckley, Donna J; Buckley, Arthur R; Nallani, Srikanth C; Desai, Pankaj B 2008. Role of human pregnane X receptor in tamoxifen- and 4-hydroxytamoxifen-mediated CYP3A4 induction in primary human hepatocytes and LS174T cells. Drug metabolism and disposition: the biological fate of chemicals, 36 5, 946-54

Dixit, Vaishali; Hariparsad, Niresh; Desai, Pankaj; Unadkat, Jashvant D 2007. In vitro LC-MS cocktail assays to simultaneously determine human cytochrome P450 activities. Biopharmaceutics & drug disposition, 28 5, 257-62

Dixit, Vaishali; Hariparsad, Niresh; Li, Fang; Desai, Pankaj; Thummel, Kenneth E; Unadkat, Jashvant D 2007. Cytochrome P450 enzymes and transporters induced by anti-human immunodeficiency virus protease inhibitors in human hepatocytes: implications for predicting clinical drug interactions. Drug metabolism and disposition: the biological fate of chemicals, 35 10, 1853-9

Al-Zoughool, Mustafa; Succop, Paul; Desai, Pankaj; Vietas, Jay; Talaska, Glenn 2006. Effect of N-glucuronidation on urinary bladder genotoxicity of 4-aminobiphenyl in male and female mice. Environmental toxicology and pharmacology, 22 2, 153-9

Desai, Pankaj B; Sane, Rucha S 2006. Metabolism and Pharmacokinetics of Anti-Cancer Drugs. Toxicology in vitro : an international journal published in association with BIBRA, 20 2, 133-4

Kelly, Burnett; Melhem, Murad; Zhang, Jianhua; Kasting, Gerald; Li, Jinsong; Krishnamoorthy, Mahesh; Heffelfinger, Sue; Rudich, Steven; Desai, Pankaj; Roy-Chaudhury, Prabir 2006. Perivascular paclitaxel wraps block arteriovenous graft stenosis in a pig model. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 21 9, 2425-31

Melhem, Murad; Kelly, Burnett; Zhang, Jianhua; Kasting, Gerald; Li, Jinsong; Davis, Harold; Heffelfinger, Sue; Desai, Pankaj; Roy-Chaudhury, Prabir 2006. Development of a local perivascular paclitaxel delivery system for hemodialysis vascular access dysfunction: polymer preparation and in vitro activity. Blood purification, 24 3, 289-98

Winhusen, Theresa; Somoza, Eugene; Singal, Bonita M; Harrer, Judy; Apparaju, Sandhya; Mezinskis, Juris; Desai, Pankaj; Elkashef, Ahmed; Chiang, C Nora; Horn, Paul 2006. Methylphenidate and cocaine: a placebo-controlled drug interaction study. Pharmacology, biochemistry, and behavior, 85 1, 29-38

Roy-Chaudhury, Prabir; Kelly, Burnett S; Melhem, Murad; Zhang, Jianhua; Li, Jinsong; Desai, Pankaj; Munda, Rino; Heffelfinger, Sue C 2005. Vascular access in hemodialysis: issues, management, and emerging concepts. Cardiology clinics, 23 3, 249-73

Roy-Chaudhury, Prabir; Kelly, Burnett S; Melhem, Murad; Zhang, Jianhua; Li, Jinsong; Desai, Pankaj; Munda, Rino; Heffelfinger, Sue C 2005. Novel therapies for hemodialysis vascular access dysfunction: fact or fiction! Blood purification, 23 1, 29-35

Setchell, Kenneth D R; Brzezinski, Amnon; Brown, Nadine M; Desai, Pankaj B; Melhem, Murad; Meredith, Trevor; Zimmer-Nechimias, Linda; Wolfe, Brian; Cohen, Yoram; Blatt, Yoav 2005. Pharmacokinetics of a slow-release formulation of soybean isoflavones in healthy postmenopausal women. Journal of agricultural and food chemistry, 53 6, 1938-44

Einhaus, Charity M; Retzinger, Andrew C; Perrotta, Andre O; Dentler, Michael D; Jakate, Abhijeet S; Desai, Pankaj B; Retzinger, Gregory S 2004. Fibrinogen-coated droplets of olive oil for delivery of docetaxel to a fibrin(ogen)-rich ascites form of a murine mammary tumor. Clinical cancer research : an official journal of the American Association for Cancer Research, 10 20, 7001-10

Hariparsad, Niresh; Nallani, Srikanth C; Sane, Rucha S; Buckley, Donna J; Buckley, Arthur R; Desai, Pankaj B 2004. Induction of CYP3A4 by efavirenz in primary human hepatocytes: comparison with rifampin and phenobarbital. Journal of clinical pharmacology, 44 11, 1273-81

Nallani, Srikanth C; Goodwin, Bryan; Buckley, Arthur R; Buckley, Donna J; Desai, Pankaj B 2004. Differences in the induction of cytochrome P450 3A4 by taxane anticancer drugs, docetaxel and paclitaxel, assessed employing primary human hepatocytes. Cancer chemotherapy and pharmacology, 54 3, 219-29

Jakate, Abhijeet S; Einhaus, Charity M; DeAnglis, Ashley P; Retzinger, Gregory S; Desai, Pankaj B 2003. Preparation, characterization, and preliminary application of fibrinogen-coated olive oil droplets for the targeted delivery of docetaxel to solid malignancies. Cancer research, 63 21, 7314-20

Nallani, Srikanth C; Glauser, Tracy A; Hariparsad, Niresh; Setchell, Kenneth; Buckley, Donna J; Buckley, Arthur R; Desai, Pankaj B 2003. Dose-dependent induction of cytochrome P450 (CYP) 3A4 and activation of pregnane X receptor by topiramate. Epilepsia, 44 12, 1521-8

Nallani, Srikanth C; Goodwin, Bryan; Maglich, Jodi M; Buckley, Donna J; Buckley, Arthur R; Desai, Pankaj B 2003. Induction of cytochrome P450 3A by paclitaxel in mice: pivotal role of the nuclear xenobiotic receptor, pregnane X receptor. Drug metabolism and disposition: the biological fate of chemicals, 31 5, 681-4

Roy-Chaudhury, Prabir; Kelly, Burnett S; Zhang, Jianhua; Narayana, Ashwath; Desai, Pankaj; Melham, Murad; Duncan, Heather; Heffelfinger, Sue C 2003. Hemodialysis vascular access dysfunction: from pathophysiology to novel therapies. Blood purification, 21 1, 99-110

Setchell, Kenneth D R; Brown, Nadine Maynard; Desai, Pankaj B; Zimmer-Nechimias, Linda; Wolfe, Brian; Jakate, Abhijeet S; Creutzinger, Vivian; Heubi, James E 2003. Bioavailability, disposition, and dose-response effects of soy isoflavones when consumed by healthy women at physiologically typical dietary intakes. The Journal of nutrition, 133 4, 1027-35

Desai, Pankaj B; Nallani, Srikanth C; Sane, Rucha S; Moore, Linda B; Goodwin, Bryan J; Buckley, Donna J; Buckley, Arthur R 2002. Induction of cytochrome P450 3A4 in primary human hepatocytes and activation of the human pregnane X receptor by tamoxifen and 4-hydroxytamoxifen. Drug metabolism and disposition: the biological fate of chemicals, 30 5, 608-12

Genter, Mary Beth; Apparaju, Sandhya; Desai, Pankaj B 2002. Induction of olfactory mucosal and liver metabolism of lidocaine by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Journal of biochemical and molecular toxicology, 16 3, 128-34

Roy-Chaudhury, Prabir; Kelly, Burnett S; Narayana, Ashwath; Desai, Pankaj; Melhem, Murad; Munda, Rino; Duncan, Heather; Heffelfinger, Sue C 2002. Hemodialysis vascular access dysfunction from basic biology to clinical intervention. Advances in renal replacement therapy, 9 2, 74-84

Stevens, Ruth E; Konsil, Julraht; Verrill, Sonya S; Roy, Partha; Desai, Pankaj B; Upmalis, David H; Cone, Frederick L 2002. Bioavailability study of a 1200 mg miconazole nitrate vaginal ovule in healthy female adults. Journal of clinical pharmacology, 42 1, 52-60