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Photo of  Vinita Takiar, MD

Vinita Takiar, MD

Associate Professor of Clinical

Associate Professor of Clinical and Vice Chair of Research

Radiation Oncology | College of Medicine

Education/Credentials
  • Residency: University of Texas, MD Anderson Cancer Center (Radiation Oncology)
  • PhD: Yale University (Cellular and Molecular Physiology)
  • Medical Degree: Yale University School of Medicine
  • Bachelor's Degree: The Johns Hopkins University (Biophysics and English)
Board Certifications & Licenses

American Board of Radiology (Radiation Oncology) (Certification Date: 20160517)

Specialties

Radiation Oncology

Contact Information
Research Interests

Radiation Oncology
Radiation Resistance
Head and Neck Cancer (including but not limited to):

  • Ear/Neck
  • Eye/Nose
  • Oral Cavity
  • Hypophaynx
  • Larynx
  • Oropharynx
  • Nasopharynx
  • Major Salivary Gland
  • Nasal Cavity
  • Sinus
  • Thyroid
  • Trachea
  • Skin of Head and Neck
  • Unknown Primary of Head and Neck
  • Head and Neck Metastases

Clinical Interests

Radiation Oncology

Thyroid Cancer

Adenocarcinoma

Adenosquamous Carcinoma

Adrenal Cancer

Adrenal Cortex Cancers

Adrenal Gland Cancers

Adrenal Rest Tumor

Adrenal Tumors

Adrenocortical Carcinoma

Anaplastic Thyroid Cancer

BRCA1 Genes

BRCA2 Genes

Breast Cancer

Cancer

Ear Canal Masses

Ear Cancer

Esthesioneuroblastoma

Follicular Thyroid Cancer

Gingival Cancers

Head and Neck Cancer

Hurthle Cell Thyroid Cancer

Hypopharyngeal Cancers

Jaw Cancers

Laryngeal Cancer

Lip Cancer

Mandible Tumors

Merkel Cell Carcinoma

Metastasis Cancers

Nasal and Paranasal Tumors

Nasal Masses

Nasopharyngeal Carcinoma

Neck Masses

Neoplasm

Nose and Sinus Cavity Cancer

Odontogenic tumors and cysts

Olfactory Neuroblastoma (Esthesioneuroblastoma)

Oncogenic Viruses

Oral Cancer

Oral Leukoplakia

Oropharyngeal Cancer

Otorhinolaryngeal Cancer

Palatal Cancers

Papillary Carcinoma

Papillary Thyroid Cancer

Paraganglioma

Parathyroid

Parotid Cancers

Parotid Disease

Parotid tumors

Pharyngeal Cancers

Phyllodes Tumor

Primitive Neuroectodermal Tumors

Salivary Gland Cancer

Sebaceous Gland Cancer

Sinonasal Skull Base Tumors

Sinus Cancer

Small Cell Lung Carcinoma

Small-Cell Lung Cancer

Solitary Pulmonary Nodule

Sublingual Gland Cancers

Temporal Bone Cancer

Thoracic Cancer

Throat Cancer

Thymic Carcinoma

Thymoma

Thymus Cancer

Thyroid and Parathyroid Disorders

Thyroid Crisis

Thyroid Nodules

Tonsillar Cancers

Tracheal Tumors

Upper Jaw Cancers

Vocal Cord Cancer

Vocal Fold Carcinoma In Situ

Peer Reviewed Publications

Dubey, Poornima; Sertorio, Mathieu; Takiar, Vinita 2022. Therapeutic Advancements in Metal and Metal Oxide Nanoparticle-Based Radiosensitization for Head and Neck Cancer Therapy. Cancers, 14 3,

Korns, Julianna; Liu, Xiaoqi; Takiar, Vinita 2022. A review of Plks: Thinking outside the (polo) box. Molecular carcinogenesis, 61 2, 254-263

Kreinbrink, Paul J; Lewis, Luke M; Redmond, Kevin P; Takiar, Vinita 2022. Reirradiation of Recurrent and Second Primary Cancers of the Head and Neck: a Review of the Contemporary Evidence. Current treatment options in oncology, 23 3, 295-310

Frankart, Andrew J; Criss, Benjamin E; Dillehay McKillip, Kelsey; Wise-Draper, Trisha; Takiar, Vinita; Kharofa, Jordan 2021. Assessing the Reliability and Positive Predictive Value of p16 as a Surrogate for Human Papillomavirus-Mediated E6/7 mRNA Expression in Squamous Cell Carcinoma of the Anal Canal. Diseases of the colon and rectum, 64 4, 459-465

Frankart, Andrew J; Frankart, Michael J; Cervenka, Brian; Tang, Alice L; Krishnan, Deepak G; Takiar, Vinita 2021. Osteoradionecrosis: Exposing the Evidence Not the Bone. International journal of radiation oncology, biology, physics, 109 5, 1206-1218

Frankart, Andrew J; Takiar, Vinita 2021. In Reply to Laurent et al. International journal of radiation oncology, biology, physics, 111 2, 584

Hernandez Brandi, Marianna; Howell, Rebecca; Power, Amelia; Tabangin, Meredith; Altaye, Mekibib; Zender, Chad A; Takiar, Vinita; Tang, Alice L 2021. Trends in Number of Women Speakers at the American Head and Neck Society Meetings, 2007-2019. JAMA otolaryngology-- head & neck surgery, 147 12, 1053-1058

Kreinbrink, P J; Li, J; Parajuli, S; Wise-Draper, T M; Choi, D L; Tang, A L; Takiar, V 2021. Pre-treatment absolute lymphocyte count predicts for improved survival in human papillomavirus (HPV)-driven oropharyngeal squamous cell carcinoma. Oral oncology, 116 , 105245

Kreinbrink, Paul J; Mierzwa, Michelle L; Huth, Brad; Redmond, Kevin P; Wise-Draper, Trisha M; Casper, Keith; Li, Junan; Takiar, Vinita 2021. Adjuvant radiation and cetuximab improves local control in head and neck cutaneous squamous cell carcinoma: Phase II study. Head & neck, 43 11, 3408-3416

Leddon, Jennifer L; Chirra, Martina; Frankart, Andrew J; Agrawal, Arushi; Roof, Logan; Trotier, Danny; Shaikh, Hira; Stone, Timothy; Jandarov, Roman; Takiar, Vinita; Wise-Draper, Trisha M 2021. Hypothyroidism in Head and Neck Squamous Cell Carcinoma Patients Receiving Radiotherapy With or Without Immune Checkpoint Inhibitors. The Laryngoscope, 131 7, E2413-E2419

Lewis, Luke; Kreinbrink, Paul; Richardson, Max; Westerfield, Morgan; Doberstein, Madeline; Zhang, Yongbin; Redmond, Kevin; Takiar, Vinita 2021. Intensity Modulated Proton Therapy Better Spares Non-Adjacent Organs and Reduces the Risk of Secondary Malignant Neoplasms in the Treatment of Sinonasal Cancers. Medical dosimetry : official journal of the American Association of Medical Dosimetrists, ,

Luginbuhl, Adam; Calder, Alyssa; Kutler, David; Zender, Chad; Wise-Draper, Trisha; Patel, Jena; Cheng, Michael; Karivedu, Vidhya; Zhan, Tingting; Parashar, Bhupesh; Gulati, Shuchi; Yao, Min; Lavertu, Pierre; Takiar, Vinita; Tang, Alice; Johnson, Jennifer; Keane, William; Curry, Joseph; Cognetti, David; Bar-Ad, Voichita 2021. Multi-Institutional Study Validates Safety of Intraoperative Cesium-131 Brachytherapy for Treatment of Recurrent Head and Neck Cancer. Frontiers in oncology, 11 , 786216

Sharma, Anish; Tang, Alice L; Takiar, Vinita; Wise-Draper, Trisha M; Langevin, Scott M 2021. Human Papillomavirus and Survival of Sinonasal Squamous Cell Carcinoma Patients: A Systematic Review and Meta-Analysis. Cancers, 13 15,

Takiar, Vinita 2021. In Reference to The Psychological Impact of Head and Neck Cancer in Pain Perception. The Laryngoscope, 131 6, E1911

von Allmen, Douglas; Tang, Alice; Takiar, Vinita; Zender, Chad; Romeo, Stephen; Masch, Jessica; Casper, Keith; Patil, Yash; Wilson, Keith; Khosla, Siddarth; Niu, Liang; Altaye, Mekibib; Tabangin, Meredith; Howell, Rebecca J 2021. Modified Head and Neck Swallow Scale: Using EORTC-QLQ-H&N35 to Predict Overall Survival. The Laryngoscope, 131 11, 2478-2482

Wicker, Christina A; Hunt, Brian G; Krishnan, Sunil; Aziz, Kathryn; Parajuli, Shobha; Palackdharry, Sarah; Elaban, William R; Wise-Draper, Trisha M; Mills, Gordon B; Waltz, Susan E; Takiar, Vinita 2021. Glutaminase inhibition with telaglenastat (CB-839) improves treatment response in combination with ionizing radiation in head and neck squamous cell carcinoma models. Cancer letters, 502 , 180-188

Wilke, Christopher; Takiar, Vinita; Wang, He; Moreno, Amy C; Tung, Shih-Ming Samuel; Quinlan-Davidson, Sean R; Garden, Adam S; Rosenthal, David I; Fuller, Clifton D; Gunn, Gary B; Reddy, Jay P; Morrison, William H; Wang, Congjun; Zhao, George; Hutcheson, Katherine A; Phan, Jack 2021. Defining the dose-volume criteria for laryngeal sparing in locally advanced oropharyngeal cancer utilizing split-field IMRT, whole-field IMRT and VMAT. Journal of applied clinical medical physics, 22 1, 37-44

Havard, Molly; Esslinger, Hope; Mierzwa, Michelle; Kharofa, Jordan; Takiar, Vinita 2020. Increased Pain Reporting by Head and Neck Cancer Patients at Radiation Oncology Consultation: A Quality-of-Life Analysis. The Laryngoscope, ,

Hunt, Brian G; Wicker, Christina A; Bourn, Jennifer R; Lower, Elyse E; Takiar, Vinita; Waltz, Susan E 2020. MST1R (RON) expression is a novel prognostic biomarker for metastatic progression in breast cancer patients. Breast cancer research and treatment, ,

Khanna, Suchin; Palackdharry, Sarah; Roof, Logan; Wicker, Christina A; Mark, Jonathan; Zhu, Zheng; Jandorav, Roman; Molinolo, Alfredo; Takiar, Vinita; Wise-Draper, Trisha M 2020. Determining the molecular landscape and impact on prognosis in HPV-associated head and neck cancer. Cancers of the head & neck, 5 , 11

Lewis, Luke M; Tang, Alice L; Wise-Draper, Trisha M; Myers, Kasiani C; Greenberger, Joel S; Takiar, Vinita 2020. Successful use of a therapeutic trial of graduated volume and dose escalation for postoperative head and neck radiotherapy in a Fanconi anemia patient. Head & neck, 42 10, E16-E22

Venkatraman, Anumitha; Kaval, Farah; Takiar, Vinita 2020. Body Mass Index and Age Affect Maximum Mouth Opening in a Contemporary American Population. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, ,

Wicker, Christina A; Takiar, Vinita; Suganya, Rangaswamy; Arnold, Susanne M; Brill, Yolanda M; Chen, Li; Horbinski, Craig M; Napier, Dana; Valentino, Joseph; Kudrimoti, Mahesh R; Yu, Guoqiang; Izumi, Tadahide 2020. Evaluation of antioxidant network proteins as novel prognostic biomarkers for head and neck cancer patients. Oral oncology, 111 , 104949

Epperson, Madison; Gouveia, Christopher J; Tabangin, Meredith E; Takiar, Vinita; Howell, Rebecca; Altaye, Mekibib; Ishman, Stacey L; Tang, Alice L 2019. Female Representation in Otolaryngology Leadership Roles. The Laryngoscope, ,

Gulati, Shuchi; Desai, Janki; Palackdharry, Sarah M; Morris, John C; Zhu, Zheng; Jandarov, Roman; Riaz, Muhammad K; Takiar, Vinita; Mierzwa, Michelle; Gutkind, J Silvio; Molinolo, Alfredo; Desai, Pankaj B; Sadraei, Nooshin Hashemi; Wise-Draper, Trisha M 2019. Phase 1 dose-finding study of metformin in combination with concurrent cisplatin and radiotherapy in patients with locally advanced head and neck squamous cell cancer. Cancer, ,

Haque, Sulsal; Karivedu, Vidhya; Riaz, Muhammed K; Choi, David; Roof, Logan; Hassan, Sarah Z; Zhu, Zheng; Jandarov, Roman; Takiar, Vinita; Tang, Alice; Wise-Draper, Trisha 2019. High-risk pathological features at the time of salvage surgery predict poor survival after definitive therapy in patients with head and neck squamous cell carcinoma. Oral oncology, 88 , 9-15

Moreno, Amy C; Wilke, Christopher; Wang, He; Tung, Shi-Ming Samuel; Pollard, Courtney; Garden, Adam S; Morrison, William H; Rosenthal, David I; Fuller, Clifton D; Gunn, Gary B; Reddy, Jay P; Shah, Shalin J; Frank, Steven J; Takiar, Vinita; Phan, Jack 2019. Optimizing laryngeal sparing with intensity modulated radiotherapy or volumetric modulated arc therapy for unilateral tonsil cancer. Physics and imaging in radiation oncology, 10 , 29-34

Forster, Neil; Warnick, Ronald; Takiar, Vinita; Pater, Luke; Breneman, John 2018. Debulking surgery of pituitary adenoma as a strategy to facilitate definitive stereotactic radiosurgery. Journal of neuro-oncology, 138 2, 335-340

Tang, Alice L; Miller, Adam; Hauff, Samantha; Myer, Charles M; Takiar, Vinita; Howell, Rebecca J; Mark, Jonathan R 2018. Maternity and paternity leave in otolaryngology residency training in the United States. The Laryngoscope, ,

Wise-Draper, Trisha; Sendilnathan, Arun; Palackdharry, Sarah; Pease, Nicholas; Qualtieri, Julianne; Butler, Randall; Sadraei, Nooshin Hashemi; Morris, John C; Patil, Yash; Wilson, Keith; Mark, Jonathan; Casper, Keith; Takiar, Vinita; Lane, Adam; Privette Vinnedge, Lisa 2018. Decreased plasma DEK Oncogene Levels Correlate with p16-Negative Disease and Advanced Tumor Stage in a Case-Control Study of Patients with Head and Neck Squamous Cell Carcinoma. Translational oncology, 11 1, 168-174

Takiar, V; Ip, C K M; Gao, M; Mills, G B; Cheung, L W T 2017. Neomorphic mutations create therapeutic challenges in cancer. Oncogene, 36 12, 1607-1618

Tuttle, Traci R; Takiar, Vinita; Kumar, Bhavna; Kumar, Pawan; Ben-Jonathan, Nira 2017. Soluble guanylate cyclase stimulators increase sensitivity to cisplatin in head and neck squamous cell carcinoma cells. Cancer letters, 389 , 33-40

Damast, Shari; Takiar, Vinita; McCarthy, Shirley; Higgins, Susan A 2016. Treatment of early stage vaginal cancer with EBRT and MRI-based intracavitary brachytherapy: A retrospective case review. Gynecologic oncology reports, 17 , 89-92

Mitra, Shreya; Federico, Lorenzo; Zhao, Wei; Dennison, Jennifer; Sarkar, Tapasree Roy; Zhang, Fan; Takiar, Vinita; Cheng, Kwai W; Mani, Sendurai; Lee, Ju Seog; Mills, Gordon B 2016. Rab25 acts as an oncogene in luminal B breast cancer and is causally associated with Snail driven EMT. Oncotarget, 7 26, 40252-40265

Phan, Jack; Sio, Terence T; Nguyen, Theresa P; Takiar, Vinita; Gunn, G Brandon; Garden, Adam S; Rosenthal, David I; Fuller, Clifton D; Morrison, William H; Beadle, Beth; Ma, Dominic; Zafereo, Mark E; Hutcheson, Kate A; Kupferman, Michael E; William, William N; Frank, Steven J 2016. Reirradiation of Head and Neck Cancers With Proton Therapy: Outcomes and Analyses. International journal of radiation oncology, biology, physics, 96 1, 30-41

Takiar, Vinita; Garden, Adam S; Ma, Dominic; Morrison, William H; Edson, Mark; Zafereo, Mark E; Gunn, Gary B; Fuller, Clifton D; Beadle, Beth; Frank, Steven J; William, William N; Kies, Merrill; El-Naggar, Adel K; Weber, Randal; Rosenthal, David I; Phan, Jack 2016. Reirradiation of Head and Neck Cancers With Intensity Modulated Radiation Therapy: Outcomes and Analyses. International journal of radiation oncology, biology, physics, 95 4, 1117-31

Takiar, Vinita; Phan, Jack 2016. In Reply to Mansha. International journal of radiation oncology, biology, physics, 96 3, 709

Takiar, Vinita; Ma, Dominic; Garden, Adam S; Li, Jing; Rosenthal, David I; Beadle, Beth M; Frank, Steven J; Fuller, Clifton D; Gunn, Gary B; Morrison, William H; Hutcheson, Kate; El-Naggar, Adel K; Gold, Kathryn A; Kupferman, Michael E; Phan, Jack 2015. Disease control and toxicity outcomes for T4 carcinoma of the nasopharynx treated with intensity-modulated radiotherapy. Head & neck, ,

Tao, Randa; Ma, Dominic; Takiar, Vinita; Frank, Steven J; Fuller, Clifton D; Gunn, G Brandon; Beadle, Beth M; Morrison, William H; Rosenthal, David I; Edson, Mark A; Esmaeli, Bita; Kupferman, Michael E; Hanna, Ehab Y; Garden, Adam S; Phan, Jack 2015. Orbital carcinomas treated with adjuvant intensity-modulated radiation therapy. Head & neck, ,

Hoffman, Karen E; Voong, K Ranh; Pugh, Thomas J; Skinner, Heath; Levy, Lawrence B; Takiar, Vinita; Choi, Seungtaek; Du, Weiliang; Frank, Steven J; Johnson, Jennifer; Kanke, James; Kudchadker, Rajat J; Lee, Andrew K; Mahmood, Usama; McGuire, Sean E; Kuban, Deborah A 2014. Risk of late toxicity in men receiving dose-escalated hypofractionated intensity modulated prostate radiation therapy: results from a randomized trial. International journal of radiation oncology, biology, physics, 88 5, 1074-84

Takiar, Vinita; Akay, Catherine L; Stauder, Michael C; Tereffe, Welela; Alvarez, Ricardo H; Hoffman, Karen E; Perkins, George H; Strom, Eric A; Buchholz, Thomas A; Ueno, Naoto T; Babiera, Gildy; Woodward, Wendy A 2014. Predictors of durable no evidence of disease status in de novo metastatic inflammatory breast cancer patients treated with neoadjuvant chemotherapy and post-mastectomy radiation. SpringerPlus, 3 , 166

Takiar, Vinita; Fontanilla, Hiral P; Eifel, Patricia J; Jhingran, Anuja; Kelly, Patrick; Iyer, Revathy B; Levenback, Charles F; Zhang, Yongbin; Dong, Lei; Klopp, Ann 2013. Anatomic distribution of fluorodeoxyglucose-avid para-aortic lymph nodes in patients with cervical cancer. International journal of radiation oncology, biology, physics, 85 4, 1045-50

Takiar, Vinita; Strom, Eric A; Baumann, Donald P; Meric-Bernstam, Funda; Alvarez, Ricardo H; Gonzalez-Angulo, Ana M 2013. Locoregional interaction of ixabepilone (ixempra) after breast cancer radiation. The oncologist, 18 3, 265-70

Lee, Daniel A; Bedont, Joseph L; Pak, Thomas; Wang, Hong; Song, Juan; Miranda-Angulo, Ana; Takiar, Vani; Charubhumi, Vanessa; Balordi, Francesca; Takebayashi, Hirohide; Aja, Susan; Ford, Eric; Fishell, Gordon; Blackshaw, Seth 2012. Tanycytes of the hypothalamic median eminence form a diet-responsive neurogenic niche. Nature neuroscience, 15 5, 700-2

Takiar, Vinita; Mistry, Kavita; Carmosino, Monica; Schaeren-Wiemers, Nicole; Caplan, Michael J 2012. VIP17/MAL expression modulates epithelial cyst formation and ciliogenesis. American journal of physiology. Cell physiology, 303 8, C862-71

Takiar, Vinita; Caplan, Michael J 2011. Polycystic kidney disease: pathogenesis and potential therapies. Biochimica et biophysica acta, 1812 10, 1337-43

Takiar, Vinita; Nishio, Saori; Seo-Mayer, Patricia; King, J Darwin; Li, Hui; Zhang, Li; Karihaloo, Anil; Hallows, Kenneth R; Somlo, Stefan; Caplan, Michael J 2011. Activating AMP-activated protein kinase (AMPK) slows renal cystogenesis. Proceedings of the National Academy of Sciences of the United States of America, 108 6, 2462-7

Takiar, Vinita; Caplan, Michael J 2010. Telling kidneys to cease and decyst. Nature medicine, 16 7, 751-2

Fuh, Katherine C; Meneshian, Avedis; Patel, Chandrahas B; Takiar, Vinita; Bulkley, Gregory B 2002. Signal transduction by reactive oxygen species: alternative paradigms for signaling specificity. Surgery, 131 6, 601-12

Fontanilla, Hiral P; Klopp, Ann H; Lindberg, Mary E; Jhingran, Anuja; Kelly, Patrick; Takiar, Vinita; Iyer, Revathy B; Levenback, Charles F; Zhang, Yongbin; Dong, Lei; Eifel, Patricia J . Anatomic distribution of [(18)F] fluorodeoxyglucose-avid lymph nodes in patients with cervical cancer. Practical radiation oncology, 3 1, 45-53

Freese, Christopher; Takiar, Vinita; Fouladi, Maryam; DeWire, Mariko; Breneman, John; Pater, Luke . Radiation and subsequent reirradiation outcomes in the treatment of diffuse intrinsic pontine glioma and a systematic review of the reirradiation literature. Practical radiation oncology, 7 2, 86-92

Takiar, Vinita; Gombos, Dan S; Mourtada, Firas; Rechner, Laura A; Lawyer, Ann A; Morrison, William H; Garden, Adam S; Beadle, Beth M . Disease control and toxicity outcomes using ruthenium eye plaque brachytherapy in the treatment of uveal melanoma. Practical radiation oncology, 4 4, e189-94

Takiar, Vinita; Pugh, Thomas J; Swanson, David; Kudchadker, Rajat J; Bruno, Teresa L; McAvoy, Sarah; Mahmood, Usama; Frank, Steven J . MRI-based sector analysis enhances prostate palladium-103 brachytherapy quality assurance in a phase II prospective trial of men with intermediate-risk localized prostate cancer. Brachytherapy, 13 1, 68-74

Takiar, Vinita; Voong, K Ranh; Gombos, Dan S; Mourtada, Firas; Rechner, Laura A; Lawyer, Ann A; Morrison, William H; Garden, Adam S; Beadle, Beth M . A choice of radionuclide: Comparative outcomes and toxicity of ruthenium-106 and iodine-125 in the definitive treatment of uveal melanoma. Practical radiation oncology, 5 3, e169-76