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Photo of  William L. Barrett, M.D.

William L. Barrett, M.D.

Department Chair

Co-Director UC Cancer Institute, Medical Director UC Barrett Cancer Center, Charles M. Barrett M.D. Endowed Chair and Professor

Radiation Oncology | College of Medicine

Education/Credentials
  • Bachelor's Degree: University of Virginia
  • Medical Degree: University of Cincinnati College of Medicine
  • Residency: University Hospital
  • Fellowship: Memorial Sloan-Kettering Cancer Center
  • Internship: University Hospital
Board Certifications & Licenses

American Board of Radiology (Radiation Oncology) (Certification Date: 19920604)

Languages

English

Specialties

Radiation Oncology

Research Interests

Radiation Oncology, Cancer, Oncology, Head & Neck Cancer, Prostate Cancer, Sarcoma, Brachytherapy

Contact Information

Clinical Interests

Radiation Oncology

Malignant Melanoma

Thyroid Cancer

Adenocarcinoma

Adenomyosis

Adenosquamous Carcinoma

Adnexal Tumors

Adrenal Cancer

Adrenal Cortex Cancers

Adrenal Gland Cancers

Adrenal Rest Tumor

Adrenal Tumors

Adrenocortical Carcinoma

Advanced Skin Cancer

Anaplastic Thyroid Cancer

Angiocarcinoma

Angiosarcoma

Basal Cell Carcinoma

Basosquamous Carcinoma

Bladder Cancer

Bone cancer

Bone Cancer Sarcoma

Bone Tissue Cancers

Bowen's Disease

BRCA1 Genes

BRCA2 Genes

Breast Cancer

Cancer

Cervical Cancer

Cutaneous B-cell lymphoma

Cutaneous Lymphoma

Cutaneous Melanoma

Cutaneous T-cell lymphoma

Dermatofibrosarcoma Protuberans (DFSP)

Ductal Breast Carcinoma

Ductal Carcinoma

Dysgerminoma

Ear Canal Masses

Ear Cancer

Eccrine Porocarcinoma

Embryonal Carcinoma

Endocrine Cancers

Endometrial Cancer

Endometrial Stromal Sarcoma

Epithelioid Sarcoma

Esthesioneuroblastoma

Follicular Thyroid Cancer

Genitourinary Cancer

Giant Cell Tumor of Tendon Sheath

Gingival Cancers

Head and Neck Cancer

Hemangiosarcoma

Hurthle Cell Thyroid Cancer

Hypopharyngeal Cancers

Hypothalamic Cancers

Intraductal Carcinoma

Intraductal Noninfiltrating Carcinoma

Jaw Cancers

Krukenberg Tumor

Laryngeal Cancer

Leiomyosarcoma

Leydig Cell Tumor

Lip Cancer

Liposarcoma

Male Genitalia Cancers

Mandible Tumors

Melanoma

Merkel Cell Carcinoma

Metastasis Cancers

Mucoepidermoid Carcinoma

Muscle Tissue Cancers

Myxofibrosarcoma

Myxosarcoma

Nasal and Paranasal Tumors

Nasal Masses

Nasopharyngeal Carcinoma

Neck Masses

Neoplasm

Nose and Sinus Cavity Cancer

Oral Cancer

Oral Leukoplakia

Oropharyngeal Cancer

Otorhinolaryngeal Cancer

Palatal Cancers

Papillary Carcinoma

Papillary Thyroid Cancer

Paraganglioma

Paranasal Sinus Cancers

Parathyroid Cancer

Parotid Cancers

Parotid Disease

Parotid tumors

Pelvic Cancers

Penile Cancer

Pharyngeal Cancers

Phyllodes Tumor

Plasma Cell Cancers

Plasmacytoma

Prostate Cancer

Renal Cancer

Renal Cell Carcinoma

Salivary Gland Cancer

Sarcoma

Scrotal masses

Sebaceous Gland Cancer

Seminoma

Sertoli Cell Tumor

Sertoli-Leydig Cell Tumor

Sinonasal Skull Base Tumors

Skin Cancer

Spine Sarcoma

Squamous Cell Carcinoma

Synovial Sarcoma

Temporal Bone Cancer

Teratocarcinoma

Testicular Cancer

Throat Cancer

Thyroid and Parathyroid Disorders

Thyroid Crisis

Thyroid Nodules

Tracheal Tumors

Upper Jaw Cancers

Ureteral Cancer

Urethral Cancer

Urogenital Cancers

Urologic Cancer

Uterine Sarcoma

Vaginal Cancer

Vocal Cord Cancer

Vocal Fold Carcinoma In Situ

Vulvar Cancer

Peer Reviewed Publications

Davis, Harold W; Vallabhapurapu, Subrahmanya D; Chu, Zhengtao; Vallabhapurapu, Swarajya L; Franco, Robert S; Mierzwa, Michelle; Kassing, William; Barrett, William L; Qi, Xiaoyang 2019. Enhanced phosphatidylserine-selective cancer therapy with irradiation and SapC-DOPS nanovesicles. Oncotarget, 10 8, 856-868

Fakhry, Carole; Zhang, Qiang; Gillison, Maura L; Nguyen-Tân, Phuc Felix; Rosenthal, David I; Weber, Randal S; Lambert, Louise; Trotti, Andy M; Barrett, William L; Thorstad, Wade L; Yom, Sue S; Wong, Stuart J; Ridge, John A; Rao, Shyam S D; Spencer, Sharon; Fortin, Andre; Raben, David; Harris, Jonathan; Le, Quynh-Thu 2019. Validation of NRG oncology/RTOG-0129 risk groups for HPV-positive and HPV-negative oropharyngeal squamous cell cancer: Implications for risk-based therapeutic intensity trials. Cancer, 125 12, 2027-2038

Fakhry, Carole; Nguyen-Tân, Phuc Felix; Lambert, Louise; Rosenthal, David I; Weber, Randal S; Gillison, Maura L; Trotti, Andy M; Barrett, William L; Thorstad, Wade L; Jones, Christopher U; Yom, Sue S; Wong, Stuart J; Ridge, John A; Rao, Shyam S D; Bonner, James A; Vigneault, Eric; Raben, David; Kudrimoti, Mahesh R; Harris, Jonathan; Le, Quynh-Thu 2018. In Regard to Bossi et al. International journal of radiation oncology, biology, physics, 102 3, 669-670

Fakhry, Carole; Zhang, Qiang; Nguyen-Tân, Phuc Felix; Rosenthal, David I; Weber, Randal S; Lambert, Louise; Trotti, Andy M; Barrett, William L; Thorstad, Wade L; Jones, Christopher U; Yom, Sue S; Wong, Stuart J; Ridge, John A; Rao, Shyam S D; Bonner, James A; Vigneault, Eric; Raben, David; Kudrimoti, Mahesh R; Harris, Jonathan; Le, Quynh-Thu; Gillison, Maura L 2017. Development and Validation of Nomograms Predictive of Overall and Progression-Free Survival in Patients With Oropharyngeal Cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 35 36, 4057-4065

Hentz C, Barrett WL. 2014. Efficacy and Morbidity of Temporary I-125 Brachtherapy in Pediatric Rhabdomyosarcomas. Brachytherapy , 13 , 196-202

Marwaha G, Barrett WL. 2014. Stage III and IV head and neck cancer: Does everyone need chemotherapy? Int. J. Otolaryngology and Head & Neck Surgery, 3 , 26-28

Coombs C, Barrett WL, Hertzfeld KE. 2012. Outcomes in Transplant Patients Undergoing Brachytherapy for Prostate Cancer. Am J Clin Oncol , 35 1, 40-44

pater LE, Hart KW, Blonigen BJ, Lindsell CJ, Barrett WL. 2012. Relationship between prostate-specific antigen, age and body mass index in a prostate cancer screening population. Am J Clin Oncol , 35 5, 490-492

Pater, Luke E; Hart, Kimberly W; Blonigen, Brian J; Lindsell, Christopher J; Barrett, William L 2012. Relationship between prostate-specific antigen, age, and body mass index in a prostate cancer screening population. American journal of clinical oncology, 35 5, 490-2

Barrett WL, Breneman JC, Lavigne R, Redmond K, Elson H, Lamba M. 2011. Tribute to Dr. Bernard S. Aron. Int. J. Radiation Oncology Biol. Phys., 78 2, 323-324

Adamson, P; Auty, D J; Ayres, D S; Backhouse, C; Barr, G; Barrett, W L; Bishai, M; Blake, A; Bock, G J; Boehnlein, D J; Bogert, D; Bower, C; Budd, S; Cavanaugh, S; Cherdack, D; Childress, S; Choudhary, B C; Coelho, J A B; Cobb, J H; Coleman, S J; Corwin, L; Cravens, J P; Cronin-Hennessy, D; Danko, I Z; de Jong, J K; Devenish, N E; Diwan, M V; Dorman, M; Escobar, C O; Evans, J J; Falk, E; Feldman, G J; Frohne, M V; Gallagher, H R; Gomes, R A; Goodman, M C; Gouffon, P; Gran, R; Grant, N; Grzelak, K; Habig, A; Harris, D; Harris, P G; Hartnell, J; Hatcher, R; Himmel, A; Holin, A; Huang, X; Hylen, J; Ilic, J; Irwin, G M; Isvan, Z; Jaffe, D E; James, C; Jensen, D; Kafka, T; Kasahara, S M S; Koizumi, G; Kopp, S; Kordosky, M; Krahn, Z; Kreymer, A; Lang, K; Lefeuvre, G; Ling, J; Litchfield, P J; Loiacono, L; Lucas, P; Mann, W A; Marshak, M L; Mayer, N; McGowan, A M; Mehdiyev, R; Meier, J R; Messier, M D; Michael, D G; Miller, J L; Miller, W H; Mishra, S R; Mitchell, J; Moore, C D; Mualem, L; Mufson, S; Musser, J; Naples, D; Nelson, J K; Newman, H B; Nichol, R J; Oliver, W P; Orchanian, M; Paley, J; Patterson, R B; Patzak, T; Pawloski, G; Pearce, G F; Pittam, R; Plunkett, R K; Ratchford, J; Raufer, T M; Rebel, B; Rodrigues, P A; Rosenfeld, C; Rubin, H A; Ryabov, V A; Sanchez, M C; Saoulidou, N; Schneps, J; Schreiner, P; Semenov, V K; Shanahan, P; Smart, W; Sousa, A; Strait, M; Tagg, N; Talaga, R L; Thomas, J; Thomson, M A; Tinti, G; Toner, R; Tzanakos, G; Urheim, J; Vahle, P; Viren, B; Weber, A; Webb, R C; White, C; Whitehead, L; Wojcicki, S G; Wright, D M; Yang, T; Zois, M; Zwaska, R 2010. Search for Lorentz invariance and CPT violation with the MINOS far detector. Physical review letters, 105 15, 151601

Barrett WL, Hertzfeld KE. 2010. Undetectable PSA level following prostate brachytherapy: An apples-to-apples comparison with radical prostatectomy. UroToday: International Journal of Urologic Oncology 3(2)., 3 2,

Barrett WL, Hertzfeld KE. 2010. Undetectable PSA level following prostate brachytherapy: An apples-to-apples comparison with radical prostatectomy. Uro Today, ,

Eckman MH, Ying J, Hertzfeld K, Kumar N, Barrett WL. 2010. Longitudinal Analysis of Genitourinary and Bowel Symptoms in Prostate Cancer Patients Following Brachytherapy Am J Clin Oncol , 33 1, 1

Mierzwa, Michelle L; Barrett, William L; Redmond, Kevin; Shirazi, Reza; Kastl, Ali; Kumar, Nitin; Buncher, Ralph 2008. Randomized trial to assess the efficacy of intraoperative steroid use in decreasing acute urinary retention after transperineal radioactive iodine-125 implantation for prostate cancer Cancer, 113 9, 2605-9

Mierzwa, Michelle L; McCluskey, Connie M; Barrett, William L; Lowy, Andrew; Sussman, Jeffrey; Sorger, Joel 2007. Interstitial brachytherapy for soft tissue sarcoma: A single institution experience Brachytherapy, 6 4, 298-303

Mishra, Mark V; Shirazi, Reza; Barrett, William L 2007. Incidence and clinical course of hemorrhagic radiation proctitis after iodine-125 prostate brachytherapy Clinical genitourinary cancer, 5 6, 397-400

Augsburger, James J; Schneider, Susan; Narayana, Ashwatha; Breneman, John C; Aron, Bernard S; Barrett, William L; Trichopoulos, Nikolaos 2004. Plaque radiotherapy for choroidal and ciliochoroidal melanomas with limited nodular extrascleral extension Canadian journal of ophthalmology. Journal canadien d, 39 4, 380-7

Barrett, William L; Gluckman, Jack L; Wilson, Keith M; Gleich, Lyon L 2004. A comparison of treatments of squamous cell carcinoma of the base of tongue: surgical resection combined with external radiation therapy, external radiation therapy alone, and external radiation therapy combined with interstitial radiation Brachytherapy, 3 4, 240-5

Barrett, William L; Kassing, William M; Shirazi, Reza 2004. Efficacy of brachytherapy for prostate cancer in African Americans compared with Caucasians Brachytherapy, 3 1, 30-3

Gleich, Lyon L; Ryzenman, John; Gluckman, Jack L; Wilson, Keith M; Barrett, William L; Redmond, Kevin P 2004. Recurrent advanced (T3 or T4) head and neck squamous cell carcinoma: is salvage possible? Archives of otolaryngology--head & neck surgery, 130 1, 35-8

Slate, Lawrence J; Elson, Howard R; Lamba, Michael A S; Kassing, William M; Soldano, Michael; Barrett, William L 2004. A Monte Carlo brachytherapy study for dose distribution prediction in an inhomogeneous medium Medical dosimetry : official journal of the American Association of Medical Dosimetrists, 29 4, 271-8

Gleich, Lyon L; Collins, C Michael; Gartside, Peter S; Gluckman, Jack L; Barrett, William L; Wilson, Keith M; Biddinger, Paul W; Redmond, Kevin P 2003. Therapeutic decision making in stages III and IV head and neck squamous cell carcinoma Archives of otolaryngology--head & neck surgery, 129 1, 26-35

Mierzwa, Michelle L; Barrett, William L; Gluckman, Jack L 2003. Radiation therapy for recurrent orbital hemangioma Head & neck, 25 5, 412-5

Barrett, William L; Gleich, Lyon; Wilson, Keith; Gluckman, Jack 2002. Organ preservation with interstitial radiation for base of tongue cancer American journal of clinical oncology, 25 5, 485-8

Barrett, W L; Aron, B S; Breneman, J C; Narayana, A; Redmond, K P 2001. Clinical oncology clerkship for third-year medical students Journal of cancer education : the official journal of the American Association for Cancer Education, 16 4, 182-4

Robertson, M L; Gleich, L L; Barrett, W L; Gluckman, J L 2001. Base-of-tongue cancer: survival, function, and quality of life after external-beam irradiation and brachytherapy The Laryngoscope, 111 8, 1362-5

Campbell, A C; Gleich, L L; Barrett, W L; Gluckman, J L 1999. Cancerous seeding of the tracheotomy site in patients with upper aerodigestive tract squamous cell carcinoma Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 120 4, 601-3

Barrett, W L; Gluckman, J L; Aron, B S 1997. Safety of radiating jejunal interposition grafts in head and neck cancer American journal of clinical oncology, 20 6, 609-12

Barrett, W L; First, M R; Aron, B S; Penn, I 1993. Clinical course of malignancies in renal transplant recipients Cancer, 72 7, 2186-9

McFadden, D W; Kelley, D J; Sigmund, D A; Barrett, W L; Dickson, B; Aron, B S 1992. Embryonal sarcoma of the liver in an adult treated with preoperative chemotherapy, radiation therapy, and hepatic lobectomy Cancer, 69 1, 39-44

Eckman MH, Ying J, Hertzfeld K, Kumar N, Barrett WL. 02-2010. Longitudinal Analysis of Genitourinary and Bowel Symptoms in Prostate Cancer Patients Following Brachytherapy. Am J Clin Oncol 2010 , 33 1, 1-10