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2025

Zamulko, Olga; Karivedu, Vidhya; Riaz, Muhammad Kashif; Monroe, Ilaina; Crago, Audrey; Mulanda, Rachel; Kurtzweil, Nicky; Forsythe, Allie; Allen, Casey L; Harun, Nusrat; Pan, Jianmin; Rai, Shesh; El-Gamal, Dalia; Wise-Draper, Trisha M 2025. Phase II study evaluating the efficacy of niraparib and dostarlimab (TSR-042) in recurrent/metastatic head and neck squamous cell carcinoma (HNSCC) patients. Cancer research communications, ,

Smith, Audrey L; Ridout, Abigail; Skupa, Sydney A; Martinez-Rico, Rolando; Drengler, Erin M; Mohamed, Eslam; D 2025. The Elevation and Impact of Peripheral Bile Acids in Chronic Lymphocytic Leukemia. Biomedicines, 13 4, 874

Drengler, E. M., Smith, A. L., Skupa, S. A., Schmitz, E., Mohamed, E., & El-Gamal, D. 2025. BET Protein Inhibition Relieves MDSC-Mediated Immune Suppression in Chronic Lymphocytic Leukemia. Hemato, 6 2, 14

Lone, Waseem; Bouska, Alyssa; Herek, Tyler A; Amador, Catalina; Song, Joo; Xu, Alexander M; Jochum, Dylan; Issa, Issa Ismail; Weisenburger, Dennis D; Zhang, Xuan; Bhagavathi, Sharath Kumar; Heavican-Foral, Tayla B; Sharma, Sunandini; Shah, Ab Rauf; Mir, Abdul Rouf; Alkhinji, Aisha Ahmad; El-Gamal, Dalia; Dave, Bhavana J; Hartert, Keenan; Yu, Jiayu; Saumyaranjan, Mallick; Greiner, Timothy C; Vose, Julie; McKeithan, Timothy W; Fu, Kai; Green, Michael; Bi, Chengfeng; Merchant, Akil; Chan, Wing C; Iqbal, Javeed 2025. High-grade B-cell lymphoma not otherwise specified, with diffuse large B-cell lymphoma gene expression signatures: Genomic analysis and potential therapeutics. American journal of hematology, 100 1, 10-22

Skupa, Sydney A; Cooper, Kathryn M; Smith, Audrey L; Drengler, Erin M; Eiken, Alexandria P; Schmitz, Elizabeth; Waldron, Grace M; Mathew, Grinu; Primeaux, Mark; Dhawan, Punita; Talmon, Geoffrey A; D'Angelo, Christopher R; El-Gamal, Dalia 2025. Gut Microbiome Profiling in Eμ-TCL1 Mice Reveals Intestinal Changes and a Dysbiotic Signature Specific to Chronic Lymphocytic Leukemia. Cancer research communications, 5 8, 1344-1358

Drengler, Erin M; Smith, Audrey L; Skupa, Sydney A; Schmitz, Elizabeth; Mohamed, Eslam; El-Gamal, Dalia 2025. BET Protein Inhibition Relieves MDSC-Mediated Immune Suppression in Chronic Lymphocytic Leukemia. Hemato, 6 2,

Witek, Matthew E; Ward, Matthew C; Bakst, Richard; Chandra, Ravi A; Chang, Steven Shih-Wei; Choi, Karen Y; Galloway, Thomas; Hanna, Glenn J; Hu, Kenneth S; Robbins, Jared; Shukla, Monica E; Siddiqui, Farzan; Takiar, Vinita; Walker, Gary V; Fu, Yunting; Margalit, Danielle N 2025. Paranasal Sinus and Nasal Cavity Cancers: Systematic Review and Executive Summary of the American Radium Society Appropriate Use Criteria. Head & neck, ,

Sheth, Maulee; Sharma, Manju; Kongsomros, Supasek; Lehn, Maria; Takebe, Takanori; Takiar, Vinita; Wise-Draper, Trisha; Chutipongtanate, Somchai; Esfandiari, Leyla 2025. Matrix stiffness modulated release of spheroid-derived extracellular vesicles and discovery of Piezo1 cargo. bioRxiv : the preprint server for biology, ,

Hosseinian, Seyedmohammadhossein; Kumar, Nitin; Takiar, Vinita; J Frankart, Andrew 2025. Geometric optimization of dose distribution in spatially fractionated radiation therapy. Physics in medicine and biology, 70 16,

Rasmi, Rajan Radha; Kovatich, Rachel; Farley, Alyssa; Sakthivel, Kunnathur Murugesan; Takiar, Vinita; Sertorio, Mathieu 2025. Targeting SREBP2 in cancer progression: Molecular mechanisms, oncogenic crosstalk, and therapeutic interventions. Cellular signalling, 135 , 112044

Shyamsunder, Shreya; Lu, Zhixin; Takiar, Vinita; Waltz, Susan E 2025. Challenges and resistance mechanisms to EGFR targeted therapies in head and neck cancers and breast cancer: Insights into RTK dependent and independent mechanisms. Oncotarget, 16 , 508-530

2024

Schmitz, Elizabeth; Ridout, Abigail; Smith, Audrey L; Eiken, Alexandria P; Skupa, Sydney A; Drengler, Erin M; Singh, Sarbjit; Rana, Sandeep; Natarajan, Amarnath; El-Gamal, Dalia 2024. Immunogenic Cell Death Traits Emitted from Chronic Lymphocytic Leukemia Cells Following Treatment with a Novel Anti-Cancer Agent, SpiD3. Biomedicines, 12 12,

Zablonski, Kevin G; Skupa, Sydney A; Eiken, Alexandria P; Sundaram, Suchitra; Mavis, Cory; Gu, Juan Jenny; Torka, Pallawi; Ghione, Paola; El-Gamal, Dalia; Hernandez-Ilizaliturri, Francisco J 2024. Targeted BET inhibition with OPN-51107 synergizes with venetoclax in chronic lymphocytic leukemia. Leukemia & lymphoma, 65 14, 2129-2137

Eiken, Alexandria P; Schmitz, Elizabeth; Drengler, Erin M; Smith, Audrey L; Skupa, Sydney A; Mohan, Kabhilan; Rana, Sandeep; Singh, Sarbjit; Mallareddy, Jayapal Reddy; Mathew, Grinu; Natarajan, Amarnath; El-Gamal, Dalia 2024. The Novel Anti-Cancer Agent, SpiD3, Is Cytotoxic in CLL Cells Resistant to Ibrutinib or Venetoclax. Hemato, 5 3, 321-339

Mahr, Anna R; Bennett-Boehm, Maia M C; Rothemejer, Frederik H; Weber, Isabelle S; Regan, Alexander K; Franzen, Josh Q; Bisson, Cami R; Truong, Angela N; Olesen, Rikke; Schleimann, Mariane H; Rauter, Claudia M; Smith, Audrey L; El-Gamal, Dalia; Søgaard, Ole S; Tolstrup, Martin; Denton, Paul W 2024. TLR9 agonism differentially impacts human NK cell-mediated direct killing and antibody-dependent cell-mediated cytotoxicity. Scientific reports, 14 1, 14595

Smith, Audrey L; Skupa, Sydney A; Eiken, Alexandria P; Reznicek, Timothy E; Schmitz, Elizabeth; Williams, Nolan; Moore, Dalia Y; D'Angelo, Christopher R; Kallam, Avyakta; Lunning, Matthew A; Bociek, R Gregory; Vose, Julie M; Mohamed, Eslam; Mahr, Anna R; Denton, Paul W; Powell, Ben; Bollag, Gideon; Rowley, M Jordan; El-Gamal, Dalia 2024. BET inhibition reforms the immune microenvironment and alleviates T cell dysfunction in chronic lymphocytic leukemia. JCI insight, 9 10,

Eiken, Alexandria P; Smith, Audrey L; Skupa, Sydney A; Schmitz, Elizabeth; Rana, Sandeep; Singh, Sarbjit; Kumar, Siddhartha; Mallareddy, Jayapal Reddy; de Cubas, Aguirre A; Krishna, Akshay; Kalluchi, Achyuth; Rowley, M Jordan; D'Angelo, Christopher R; Lunning, Matthew A; Bociek, R Gregory; Vose, Julie M; Natarajan, Amarnath; El-Gamal, Dalia 2024. Novel Spirocyclic Dimer, SpiD3, Targets Chronic Lymphocytic Leukemia Survival Pathways with Potent Preclinical Effects. Cancer research communications, 4 5, 1328-1343

Mohamed, Abdallah S R; Martin, Geoffrey V; Ng, Sweet Ping; Takiar, Vinita; Beadle, Beth M; Zafereo, Mark; Garden, Adam S; Frank, Steven J; David Fuller, C; Brandon Gunn, G; Morrison, William H; Rosenthal, David I; Reddy, Jay; Moreno, Amy; Lee, Anna; Phan, Jack 2024. Patterns of failure for recurrent head and neck squamous cell carcinoma treated with salvage surgery and postoperative IMRT reirradiation. Clinical and translational radiation oncology, 44 , 100700

Mell, Loren K; Torres-Saavedra, Pedro A; Wong, Stuart J; Kish, Julie A; Chang, Steven S; Jordan, Richard C; Liu, Tian; Truong, Minh Tam; Winquist, Eric W; Takiar, Vinita; Wise-Draper, Trisha; Robbins, Jared R; Rodriguez, Cristina P; Awan, Musaddiq J; Beadle, Beth M; Henson, Christina; Narayan, Samir; Spencer, Sharon A; Powell, Steven; Dunlap, Neal; Sacco, Assuntina G; Hu, Kenneth Shung; Park, Henry S; Bauman, Julie E; Harris, Jonathan; Yom, Sue S; Le, Quynh-Thu 2024. Radiotherapy with cetuximab or durvalumab for locoregionally advanced head and neck cancer in patients with a contraindication to cisplatin (NRG-HN004): an open-label, multicentre, parallel-group, randomised, phase 2/3 trial. The Lancet. Oncology, 25 12, 1576-1588

Korns, Julianna; Wicker, Christina A; Lehn, Maria; Shyamsunder, Shreya; Thompson, Samuel; Lester, Carissa; Wise-Draper, Trisha M; Waltz, Susan E; Takiar, Vinita 2024. Telaglenastat as an alternative to cisplatin as a radiosensitizer in the treatment of head and neck squamous cell carcinoma. Cancer letters, 606 , 217320

Sheth, Maulee; Sharma, Manju; Lehn, Maria; Reza, HasanAl; Takebe, Takanori; Takiar, Vinita; Wise-Draper, Trisha; Esfandiari, Leyla 2024. Three-dimensional matrix stiffness modulates mechanosensitive and phenotypic alterations in oral squamous cell carcinoma spheroids. APL bioengineering, 8 3, 036106

Zhou, Anna; Sharma, Anish; Kuhnell, Damaris; Hinrichs, Benjamin H; Kendler, Ady; Wang, Jiang; Dillehey-McKillip, Kelsey; Tang, Alice L; Takiar, Vinita; Wise-Draper, Trisha M; Langevin, Scott M 2024. Multimodal assessment of high-risk human papillomavirus in sinonasal squamous cell carcinoma. Pathology, research and practice, 261 , 155486

Keltner, Samuel; Esslinger, Hope; Wu, Xiaoyong; Rai, Shesh; Takiar, Vinita 2024. Refining Surveillance Guidelines after Stereotactic Body Radiation Therapy for Early-Stage Lung Cancer. Clinical lung cancer, 25 6, e268-e276.e1

Petery, Taylor; Frankart, Andrew J; Esslinger, Hope; Wu, Xiaoyong; Rai, Shesh N; Takiar, Vinita 2024. The effect of treatment package time on locally advanced oral cavity cancer outcomes. Oral oncology, 154 , 106870

2023

Eiken, Alexandria P; El-Gamal, Dalia 2023. Editorial for the IJMS Special Issue on Molecular Pathogenesis and Molecular Therapy of Lymphoid Malignancies. International journal of molecular sciences, 25 1,

Smith, Audrey L; Pal, Dhananjaya; Martinez-Rico, Rolando; Eiken, Alexandria P; Durden, Donald L; Kutateladze, Tatiana G; El-Gamal, Dalia 2023. Preclinical activity of a novel multi-axis inhibitor in aggressive and indolent B-cell malignancies. Leukemia & lymphoma, 64 14, 2333-2337

Upadhyay Banskota, Shristi; Skupa, Sydney A; El-Gamal, Dalia; D'Angelo, Christopher R 2023. Defining the Role of the Gut Microbiome in the Pathogenesis and Treatment of Lymphoid Malignancies. International journal of molecular sciences, 24 3,

D'Angelo, Christopher; Sudakaran, Sailendharan; Asimakopoulos, Fotis; Hematti, Peiman; El-Gamal, Dalia; Safdar, Nasia; Callander, Natalie 2023. Perturbation of the gut microbiome and association with outcomes following autologous stem cell transplantation in patients with multiple myeloma. Leukemia & lymphoma, 64 1, 87-97

Bonomi, Marcelo; Blakaj, Dukagjin M; Kabarriti, Rafi; Colvett, Kyle; Takiar, Vinita; Biagioli, Matthew; Bar-Ad, Voichita; Goyal, Sharad; Muzyka, Brian; Niermann, Kenneth; Abrouk, Nacer; Oronsky, Bryan; Reid, Tony; Caroen, Scott; Sonis, Stephen; Sher, David J 2023. PREVLAR: Phase 2a Randomized Trial to Assess the Safety and Efficacy of RRx-001 in the Attenuation of Oral Mucositis in Patients Receiving Head and Neck Chemoradiotherapy. International journal of radiation oncology, biology, physics, 116 3, 551-559

Gulati, Shuchi; Crist, McKenzie; Riaz, Muhammed Kashif; Takiar, Vinita; Lehn, Maria; Monroe, Ilaina; Palackdharry, Sarah; Kurtzweil, Nicky; Jandarov, Roman; Harun, Nusrat; Wise-Draper, Trisha M 2023. Durvalumab plus Cetuximab in Patients with Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma: An Open-label, Nonrandomized, Phase II Clinical Trial. Clinical cancer research : an official journal of the American Association for Cancer Research, 29 10, 1906-1915

Peterson, Joseph R; Cole, John A; Pfeiffer, John R; Norris, Gregory H; Zhang, Yuhan; Lopez-Ramos, Dorys; Pandey, Tushar; Biancalana, Matthew; Esslinger, Hope R; Antony, Anuja K; Takiar, Vinita 2023. Novel computational biology modeling system can accurately forecast response to neoadjuvant therapy in early breast cancer. Breast cancer research : BCR, 25 1, 54

Medek, Sara; Correa, Zelia M; Huth, Brad; Takiar, Vinita 2023. Early treatment and toxicity outcomes for small posterior uveal melanomas treated using custom loaded eye plaques. Frontiers in medicine, 10 , 1055141

Korns, Julianna; McCauley, Shelby; Lehn, Maria; Takiar, Vinita; Sertorio, Mathieu; Lamba, Michael 2023. Varied Photon Radiation Sources Produce Differences in Cellular Response. Radiation research, 199 4, 422-428

Baniel, Claire C; Klebaner, Daniella; Beadle, Beth M; Ponce, Sara E Beltrán; Takiar, Vinita; Gibbs, Iris C; Soltys, Scott G; Bagshaw, Hilary P; Chang, Daniel T; Le, Quynh-Thu; Pollom, Erqi L 2023. Reflections on the 2021 Accreditation Council for Graduate Medical Education and American Board of Radiology Family and Medical Leave of Absence Policies: An Opportunity to Increase Structural Support for Physicians. International journal of radiation oncology, biology, physics, 115 1, 19-22

Galiveti, Chenna R; Kuhnell, Damaris; Biesiada, Jacek; Zhang, Xiang; Kelsey, Karl T; Takiar, Vinita; Tang, Alice L; Wise-Draper, Trisha M; Medvedovic, Mario; Kasper, Susan; Langevin, Scott M 2023. Small extravesicular microRNA in head and neck squamous cell carcinoma and its potential as a liquid biopsy for early detection. Head & neck, 45 1, 212-224

Hanna, Glenn J; Chang, Steven Shih-Wei; Siddiqui, Farzan; Bain, Paul A; Takiar, Vinita; Ward, Matthew C; Shukla, Monica E; Hu, Kenneth S; Robbins, Jared; Witek, Matthew E; Bakst, Richard; Chandra, Ravi A; Galloway, Thomas; Margalit, Danielle N 2023. Imaging and Biomarker Surveillance for Head and Neck Squamous cell carcinoma: A Systematic Review and Appropriate Use Criteria Document. International journal of radiation oncology, biology, physics, ,

Takiar, Vinita; Beadle, Beth M 2023. In Regard to Razavian et al. International journal of radiation oncology, biology, physics, 117 5, 1298-1299

Bouranis, John A; Wong, Carmen P; Beaver, Laura M; Uesugi, Sandra L; Papenhausen, Ethan M; Choi, Jaewoo; Davis, Edward W; Da Silva, Adilson Nunes; Kalengamaliro, Newton; Chaudhary, Rekha; Kharofa, Jordan; Takiar, Vinita; Herzog, Thomas J; Barrett, William; Ho, Emily 2023. Sulforaphane Bioavailability in Healthy Subjects Fed a Single Serving of Fresh Broccoli Microgreens. Foods (Basel, Switzerland), 12 20,

2022

Vann, Kendra R; Acharya, Arpan; Jang, Suk Min; Lachance, Catherine; Zandian, Mohamad; Holt, Tina A; Smith, Audrey L; Pandey, Kabita; Durden, Donald L; El-Gamal, Dalia; Côté, Jacques; Byrareddy, Siddappa N; Kutateladze, Tatiana G 2022. Binding of the SARS-CoV-2 envelope E protein to human BRD4 is essential for infection. Structure (London, England : 1993), 30 9, 1224-1232.e5

Smith, Audrey L; Eiken, Alexandria P; Skupa, Sydney A; Moore, Dalia Y; Umeta, Lelisse T; Smith, Lynette M; Lyden, Elizabeth R; D'Angelo, Christopher R; Kallam, Avyakta; Vose, Julie M; Kutateladze, Tatiana G; El-Gamal, Dalia 2022. A Novel Triple-Action Inhibitor Targeting B-Cell Receptor Signaling and BRD4 Demonstrates Preclinical Activity in Chronic Lymphocytic Leukemia. International journal of molecular sciences, 23 12,

Struble, Lucas R; Smith, Audrey L; Lutz, William E; Grubbs, Gabrielle; Sagar, Satish; Bayles, Kenneth W; Radhakrishnan, Prakash; Khurana, Surender; El-Gamal, Dalia; Borgstahl, Gloria E O 2022. Insect cell expression and purification of recombinant SARS-COV-2 spike proteins that demonstrate ACE2 binding. Protein science : a publication of the Protein Society, 31 5, e4300

Vann, Kendra R; Pal, Dhananjaya; Smith, Audrey L; Sahar, Namood-E; Krishnaiah, Maddeboina; El-Gamal, Dalia; Kutateladze, Tatiana G 2022. Combinatorial inhibition of BTK, PI3K-AKT and BRD4-MYC as a strategy for treatment of mantle cell lymphoma. Molecular biomedicine, 3 1, 2

Kreinbrink, Paul J; Lewis, Luke M; Redmond, Kevin P; Takiar, Vinita 2022. Reirradiation of Recurrent and Second Primary Cancers of the Head and Neck: a Review of the Contemporary Evidence. Current treatment options in oncology, 23 3, 295-310

Korns, Julianna; Liu, Xiaoqi; Takiar, Vinita 2022. A review of Plks: Thinking outside the (polo) box. Molecular carcinogenesis, 61 2, 254-263

Dubey, Poornima; Sertorio, Mathieu; Takiar, Vinita 2022. Therapeutic Advancements in Metal and Metal Oxide Nanoparticle-Based Radiosensitization for Head and Neck Cancer Therapy. Cancers, 14 3,

Frankart, Andrew J; Abana, Chike O; Geier, Natalie; Bahig, Houda; Manzar, Gohar Shahwar; Garden, Adam S; Phan, Jack; Takiar, Vinita 2022. Long-term Locoregional Control With Unilateral Radiation for AJCC-7 T1-2N2b Tonsillar Cancer. American journal of clinical oncology, 45 10, 422-426

Nelson, Bailey; Takiar, Vinita 2022. Low Risk, High Risk: Adjuvant Therapy in Resected p16+ Oropharyngeal Cancer with ?5 Positive Ipsilateral Lymph Nodes. International journal of radiation oncology, biology, physics, 114 1, 10-11

Leddon, Jennifer L; Gulati, Shuchi; Haque, Sulsal; Allen, Casey; Palackdharry, Sarah; Mathews, Maria; Kurtzweil, Nicky; Riaz, Muhammed Kashif; Takiar, Vinita; Nagasaka, Misako; Patil, Yash; Zender, Chad; Tang, Alice; Cervenka, Brian; McGrath, Julie; Korn, W Michael; Hinrichs, Benjamin H; Jandarov, Roman; Harun, Nusrat; Sukari, Ammar; Wise-Draper, Trisha M 2022. Phase II Trial of Adjuvant Nivolumab Following Salvage Resection in Patients with Recurrent Squamous Cell Carcinoma of the Head and Neck. Clinical cancer research : an official journal of the American Association for Cancer Research, 28 16, 3464-3472

Thompson, Samuel; Lewis, Luke; Takiar, Vinita 2022. Hospital Price Transparency Rule Exposes Muddied Costs for Head and Neck Radiotherapy in One State. American journal of clinical oncology, 45 6, 268-272

Wise-Draper, Trisha M; Gulati, Shuchi; Palackdharry, Sarah; Hinrichs, Benjamin H; Worden, Francis P; Old, Matthew O; Dunlap, Neal E; Kaczmar, John M; Patil, Yash; Riaz, Muhammed Kashif; Tang, Alice; Mark, Jonathan; Zender, Chad; Gillenwater, Ann M; Bell, Diana; Kurtzweil, Nicky; Mathews, Maria; Allen, Casey L; Mierzwa, Michelle L; Casper, Keith; Jandarov, Roman; Medvedovic, Mario; Lee, J Jack; Harun, Nusrat; Takiar, Vinita; Gillison, Maura 2022. Phase II Clinical Trial of Neoadjuvant and Adjuvant Pembrolizumab in Resectable Local-Regionally Advanced Head and Neck Squamous Cell Carcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research, 28 7, 1345-1352

Frankart, Andrew J; Sadraei, Nooshin Hashemi; Huth, Brad; Redmond, Kevin P; Barrett, William L; Kurtzweil, Nicky; Riaz, Muhammad K; Wise-Draper, Trisha; Rodriguez, Cristina P; Adelstein, David J; Takiar, Vinita 2022. A phase I/II trial of concurrent immunotherapy with chemoradiation in locally advanced larynx cancer. Laryngoscope investigative otolaryngology, 7 2, 437-443

Crist, McKenzie; Yaniv, Benyamin; Palackdharry, Sarah; Lehn, Maria A; Medvedovic, Mario; Stone, Timothy; Gulati, Shuchi; Karivedu, Vidhya; Borchers, Michael; Fuhrman, Bethany; Crago, Audrey; Curry, Joseph; Martinez-Outschoorn, Ubaldo; Takiar, Vinita; Wise-Draper, Trisha M 2022. Metformin increases natural killer cell functions in head and neck squamous cell carcinoma through CXCL1 inhibition. Journal for immunotherapy of cancer, 10 11,

Wicker, Christina A; Petery, Taylor; Dubey, Poornima; Wise-Draper, Trisha M; Takiar, Vinita 2022. Improving Radiotherapy Response in the Treatment of Head and Neck Cancer. Critical reviews in oncogenesis, 27 2, 73-84