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Department of

Surgery

Photo of  Alin Girnita, MD

Alin Girnita, MD

Associate Professor of Surgery

Education/Credentials
  • Bachelor's Degree: Carol I National College - Romania
  • Medical Degree: University of Medicine and Pharmacy - Romania
  • Internship : University of Medicine and Pharmacy - Romania
  • Residency: Fundeni Cardiovascular Disease National Center Hospital
  • Postdoctoral: University of Pittsburgh
  • Fellowship: University of Pittsburgh

Board Certifications & Licenses
  • Board Certified Diplomate American Board of Histocompatibility and Immunogenetics, 2004
  • Board Certified Director American Society of Histocompatibility and Immunogenetics, 2010
Contact Information
  • Hoxworth Blood Center
  • Room 5074
  • 3130 Highland Avenue
  • Cincinnati, Ohio 45267
  • Office 513-558-1515
  • Email alin.girnita@uc.edu

Peer Reviewed Publications

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Krisl, Jill C; Alloway, Rita R; Shield, Adele Rike; Govil, Amit; Mogilishetty, Gautham; Cardi, Michael; Diwan, Tayyab; Abu Jawdeh, Bassam G; Girnita, Alin; Witte, David; Woodle, E Steve 2015. Acute Rejection Clinically Defined Phenotypes Correlate With Long-Term Renal Allograft Survival. Transplantation, ,

Schmidt, Nicole; Alloway, Rita R; Walsh, R Carlin; Sadaka, Basma; Shields, Adele R; Girnita, Alin L; Hanseman, Dennis J; Woodle, E Steve 2012. Prospective evaluation of the toxicity profile of proteasome inhibitor-based therapy in renal transplant candidates and recipients. Transplantation, 94 4, 352-61

Walsh, R Carlin; Alloway, Rita R; Girnita, Alin L; Woodle, E Steve 2012. Proteasome inhibitor-based therapy for antibody-mediated rejection. Kidney international, 81 11, 1067-74

Walsh, R Carlin; Brailey, Paul; Girnita, Alin; Alloway, Rita R; Shields, Adele Rike; Wall, Garth E; Sadaka, Basma H; Cardi, Michael; Tevar, Amit; Govil, Amit; Mogilishetty, Gautham; Roy-Chaudhury, Prabir; Woodle, E Steve 2011. Early and late acute antibody-mediated rejection differ immunologically and in response to proteasome inhibition. Transplantation, 91 11, 1218-26

Woodle, E Steve; Alloway, Rita R; Girnita, Alin 2011. Proteasome inhibitor treatment of antibody-mediated allograft rejection. Current opinion in organ transplantation, 16 4, 434-8

Batal, Ibrahim; Zeevi, Adriana; Lunz, John G; Aggarwal, Nidhi; Shapiro, Ron; Randhawa, Parmjeet; Girnita, Alin 2010. Antihuman leukocyte antigen–specific antibody strength determined by complement-dependent or solid-phase assays can predict positive donor-specific crossmatches. Archives of pathology & laboratory medicine, 134 10, 1534-40

Girnita, Alin; Mazariegos, George V; Castellaneta, Antonino; Reyes, Jorge; Bentlejewski, Carol; Thomson, Angus W; Zeevi, Adriana 2010. Liver transplant recipients weaned off immunosuppression lack circulating donor-specific antibodies. Human immunology, 71 3, 274-6

Batal, Ibrahim; Zainah, Hanady; Stockhausen, Sean; Basu, Amit; Tan, Henkie; Shapiro, Ron; Zeevi, Adriana; Girnita, Alin; Randhawa, Parmjeet 2009. The significance of renal C4d staining in patients with BK viruria, viremia, and nephropathy. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 22 11, 1468-76

Girnita, Diana M; Webber, Steven A; Brooks, Maria M; Ferrell, Robert; Girnita, Alin L; Burckart, Gilbert J; Chinnock, Richard; Canter, Charles; Addonizio, Linda; Bernstein, Daniel; Kirklin, James K; Naftel, David; Zeevi, Adriana 2009. Genotypic variation and phenotypic characterization of granzyme B gene polymorphisms. Transplantation, 87 12, 1801-6

Govil, Amit; Walsh, R Carlin; Tevar, Amit; Alloway, Rita; Roy-Chaudhury, Prabir; Mogilishetty, Gautham; Wall, Garth E; Brailey, Paul; Girnita, Alin; Woodle, E Steve 2009. Bortezomib-based treatment of antibody mediated rejection in pancreas allograft recipients. Clinical transplants, , 443-53

Gupta, Gaurav; Shapiro, Ron; Girnita, Alin; Batal, Ibrahim; McCauley, Jerry; Basu, Amit; Tan, Henkie; Randhawa, Parmjeet 2009. Neutrophilic tubulitis as a marker for urinary tract infection in renal allograft biopsies with C4d deposition. Transplantation, 87 7, 1013-8

Zeevi, Adriana; Lunz, John G; Shapiro, Ron; Randhawa, Parmjeet; Mazariegos, George; Webber, Steven; Girnita, Alin 2009. Emerging role of donor-specific anti-human leukocyte antigen antibody determination for clinical management after solid organ transplantation. Human immunology, 70 8, 645-50

Batal, Ibrahim; Girnita, Alin; Zeevi, Adriana; Saab, Bassel Abou; Stockhausen, Sean; Shapiro, Ron; Basu, Amit; Tan, Henkie; Morgan, Claire; Randhawa, Parmjeet 2008. Clinical significance of the distribution of C4d deposits in different anatomic compartments of the allograft kidney. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 21 12, 1490-8

Batal, Ibrahim; Zeevi, Adriana; Heider, Amer; Girnita, Alin; Basu, Amit; Tan, Henkie; Shapiro, Ron; Randhawa, Parmjeet 2008. Measurements of global cell-mediated immunity in renal transplant recipients with BK virus reactivation. American journal of clinical pathology, 129 4, 587-91

Duquesnoy, Rene J; Awadalla, Yehia; Lomago, Jon; Jelinek, Larry; Howe, Judy; Zern, Dwayne; Hunter, Betty; Martell, Joan; Girnita, Alin; Zeevi, Adriana 2008. Retransplant candidates have donor-specific antibodies that react with structurally defined HLA-DR,DQ,DP epitopes. Transplant immunology, 18 4, 352-60

Girnita, Alin L; Lee, Teresa M; McCurry, Kenneth R; Baldwin, William M; Yousem, Samuel A; Detrick, Barbara; Pilewski, Joseph; Toyoda, Yoshiya; Jelinek, Larry; Lomago, Jon; Zaldonis, Diana; Spichty, Kathy J; Zeevi, Adriana 2008. Anti-human leukocyte antigen antibodies, vascular C4d deposition and increased soluble c4d in broncho-alveolar lavage of lung allografts. Transplantation, 86 2, 342-7

Girnita, Diana M; Brooks, Maria M; Webber, Steven A; Burckart, Gilbert J; Ferrell, Robert; Zdanowicz, Gina; DeCroo, Susan; Smith, Louise; Chinnock, Richard; Canter, Charles; Addonizio, Linda; Bernstein, Daniel; Kirklin, James K; Ranganathan, Sarangarajan; Naftel, David; Girnita, Alin L; Zeevi, Adriana 2008. Genetic polymorphisms impact the risk of acute rejection in pediatric heart transplantation: a multi-institutional study. Transplantation, 85 11, 1632-9

Kayler, Liise K; Kiss, Lawrence; Sharma, Vivek; Mohanka, Ravi; Zeevi, Adriana; Girnita, Alin; Shapiro, Ron; Randhawa, Parmjeet S 2008. Acute renal allograft rejection: diagnostic significance of focal peritubular capillary C4d. Transplantation, 85 6, 813-20

Mazariegos, George V; Soltys, Kyle; Bond, Geoffrey; Girnita, Alin; Machaidze, Zurab; Jaffe, Ronald; Green, Michael; Martin, Dolly; Zeevi, Adriana; Squires, Robert; Perez, Graciela; Abu-Elmagd, Kareem; Sindhi, Rakesh 2008. Pediatric intestinal retransplantation: techniques, management, and outcomes. Transplantation, 86 12, 1777-82

Shapiro, Ron; Zeevi, Adriana; Basu, Amit; Tan, Henkie P; Kayler, Liise K; Blisard, Deanna M; Thai, Ngoc L; Girnita, Alin L; Randhawa, Parmjeet S; Gray, Edward A; Marcos, Amadeo; Starzl, Thomas E 2008. Alemtuzumab preconditioning with tacrolimus monotherapy-the impact of serial monitoring for donor-specific antibody. Transplantation, 85 8, 1125-32

Feingold, Brian; Bowman, Pam; Zeevi, Adriana; Girnita, Alin L; Quivers, Eric S; Miller, Susan A; Webber, Steven A 2007. Survival in allosensitized children after listing for cardiac transplantation. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 26 6, 565-71

Girnita, Alin L; McCurry, Kenneth R; Zeevi, Adriana 2007. Increased lung allograft failure in patients with HLA-specific antibody. Clinical transplants, , 231-9

Girnita, Alin L; McCurry, Kenneth R; Yousem, Samuel A; Pilewski, Joseph; Zeevi, Adriana 2006. Antibody-mediated rejection in lung transplantation: case reports. Clinical transplants, , 508-10

Girnita, Alin L; Webber, Steven A; Zeevi, Adriana 2006. Anti-HLA alloantibodies in pediatric solid organ transplantation. Pediatric transplantation, 10 2, 146-53

Girnita, Diana M; Webber, Steven A; Ferrell, Robert; Burckart, Gilbert J; Brooks, Maria M; McDade, Kevin K; Chinnock, Richard; Canter, Charles; Addonizio, Linda; Bernstein, Daniel; Kirklin, James K; Girnita, Alin L; Zeevi, Adriana 2006. Disparate distribution of 16 candidate single nucleotide polymorphisms among racial and ethnic groups of pediatric heart transplant patients. Transplantation, 82 12, 1774-80

Zeevi, Adriana; Girnita, Alin; Duquesnoy, Rene 2006. HLA antibody analysis: sensitivity, specificity, and clinical significance in solid organ transplantation. Immunologic research, 36 1-3, 255-64

Adeyi, Oyedele A; Girnita, Alin L; Howe, Judy; Marrari, Marilyn; Awadalla, Yehia; Askar, Medhat; Martell, Joan; Zeevi, Adrian; Shapiro, Ron; Nalesnik, Michael; Randhawa, Parmjeet; Demetris, Anthony J; Duquesnoy, René J 2005. Serum analysis after transplant nephrectomy reveals restricted antibody specificity patterns against structurally defined HLA class I mismatches. Transplant immunology, 14 1, 53-62

Di Filippo, Sylvie; Girnita, Alin; Webber, Steven A; Tsao, Sabrina; Boyle, Gerard J; Miller, Susan A; Gandhi, Sanjiv K; Zeevi, Adriana 2005. Impact of ELISA-detected anti-HLA antibodies on pediatric cardiac allograft outcome. Human immunology, 66 5, 513-8

Girnita, Alin L; Duquesnoy, Rene; Yousem, Samuel A; Iacono, Aldo T; Corcoran, Timothy E; Buzoianu, Manuela; Johnson, Bruce; Spichty, Kathy J; Dauber, James H; Burckart, Gilbert; Griffith, Bartley P; McCurry, Kenneth R; Zeevi, Adriana 2005. HLA-specific antibodies are risk factors for lymphocytic bronchiolitis and chronic lung allograft dysfunction. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 5 1, 131-8

McCurry, Kenneth R; Iacono, Aldo; Zeevi, Adrianna; Yousem, Samuel; Girnita, Alin; Husain, Shahid; Zaldonis, Diana; Johnson, Bruce; Hattler, Brack G; Starzl, Thomas E 2005. Early outcomes in human lung transplantation with Thymoglobulin or Campath-1H for recipient pretreatment followed by posttransplant tacrolimus near-monotherapy. The Journal of thoracic and cardiovascular surgery, 130 2, 528-37

Shapiro, Ron; Basu, Amit; Tan, Henkie; Gray, Edward; Kahn, Akhtar; Randhawa, Parmjeet; Murase, Noriko; Zeevi, Adriana; Girnita, Alin; Metes, Diana; Ness, Roberta; Bass, Debra C; Demetris, Anthony J; Fung, John J; Marcos, Amadeo; Starzl, Thomas E 2005. Kidney transplantation under minimal immunosuppression after pretransplant lymphoid depletion with Thymoglobulin or Campath. Journal of the American College of Surgeons, 200 4, 505-15; quiz A59-61

Girnita, Alin L; McCurry, Kenneth R; Iacono, Aldo T; Duquesnoy, Rene; Corcoran, Timothy E; Awad, Mohamed; Spichty, Kathy J; Yousem, Samuel A; Burckart, Gilbert; Dauber, James H; Griffith, Bartley P; Zeevi, Adriana 2004. HLA-specific antibodies are associated with high-grade and persistent-recurrent lung allograft acute rejection. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 23 10, 1135-41

Mazariegos, George V; Abu-Elmagd, Kareem; Jaffe, Ronald; Bond, Geoffrey; Sindhi, Rakesh; Martin, Lillian; Macedo, Camila; Peters, John; Girnita, Alin; Reyes, Jorge 2004. Graft versus host disease in intestinal transplantation. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 4 9, 1459-65

Miller, Geraldine G; Destarac, Luis; Zeevi, Adriana; Girnita, Alin; McCurry, Kenneth; Iacono, Aldo; Murray, John J; Crowe, Deborah; Johnson, Joyce E; Ninan, Mathew; Milstone, Aaron P 2004. Acute humoral rejection of human lung allografts and elevation of C4d in bronchoalveolar lavage fluid. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 4 8, 1323-30