Education/CredentialsFellowship: Yale University School of Medicine (Surgical Pathology )Residency: University of Cincinnati College of Medicine (Pathology-Anatomic and Clinical )Doctorate: Henan Medical University, ZhengzhouMedical Degree: Henan Medical University, Zhengzhou Board Certifications & LicensesAmerican Board of Pathology (Anatomic Pathology) (Certification Date: 2008-07-31) - (Recertification Date: 2019-01-01) SpecialtiesPathology Contact Information Email wajn@ucmail.uc.edu Research InterestsSurgical pathology, GI/ Liver pathology, Transplant pathology, Cytopathology Clinical Interests Pathology Peer Reviewed Publications Rani, Richa; Sharma, Akanksha; Wang, Jiang; Kumar, Sudhir; Polaki, Usha S; Gandhi, Chandrashekhar R 2022. Endotoxin-Stimulated Hepatic Stellate Cells Augment Acetaminophen-Induced Hepatocyte Injury. The American journal of pathology, 192 3, 518-535Chakrabarti, Jayati; Koh, Vivien; Steele, Nina; Hawkins, Jennifer; Ito, Yoshiaki; Merchant, Juanita L; Wang, Jiang; Helmrath, Michael A; Ahmad, Syed A; So, Jimmy Bok Yan; Yong, Wei Peng; Zavros, Yana 2021. Disruption of Her2-Induced PD-L1 Inhibits Tumor Cell Immune Evasion in Patient-Derived Gastric Cancer Organoids. Cancers, 13 24, Khawar, Muhammad Umair; Tiwana, Maida; Sengupta, Ruchira; Wang, Jiang; Indihar, Veronica 2021. The reverse halo sign and spontaneous pneumothorax due to pulmonary mucormycosis. Respirology case reports, 9 3, e00712Koh, Vivien; Chakrabarti, Jayati; Torvund, Meaghan; Steele, Nina; Hawkins, Jennifer A; Ito, Yoshiaki; Wang, Jiang; Helmrath, Michael A; Merchant, Juanita L; Ahmed, Syed A; Shabbir, Asim; Yan So, Jimmy Bok; Yong, Wei Peng; Zavros, Yana 2021. Hedgehog transcriptional effector GLI mediates mTOR-Induced PD-L1 expression in gastric cancer organoids. Cancer letters, 518 , 59-71Lindquist, Diana M; Fugate, Elizabeth M; Wang, Jiang; Sharma, Akanksha; Gandhi, Chandrashekhar R; Dillman, Jonathan R 2021. MRI Measures of Murine Liver Fibrosis. Journal of magnetic resonance imaging : JMRI, 54 3, 739-749Vilfranc, Chrystelle L; Che, Li-Xiao; Patra, Krushna C; Niu, Liang; Olowokure, Olugbenga; Wang, Jiang; Shah, Shimul A; Du, Chun-Ying 2021. BIR repeat-containing ubiquitin conjugating enzyme (BRUCE) regulation of ?-catenin signaling in the progression of drug-induced hepatic fibrosis and carcinogenesis. World journal of hepatology, 13 3, 343-361Yang, Yongguang; Leonard, Marissa; Luo, Zhenhua; Yeo, Syn; Bick, Gregory; Hao, Mingang; Cai, Chunmiao; Charif, Mahmoud; Wang, Jiang; Guan, Jun-Lin; Lower, Elyse E; Zhang, Xiaoting 2021. Functional cooperation between co-amplified genes promotes aggressive phenotypes of HER2-positive breast cancer. Cell reports, 34 10, 108822Holokai, Loryn; Chakrabarti, Jayati; Lundy, Joanne; Croagh, Daniel; Adhikary, Pritha; Richards, Scott S; Woodson, Chantal; Steele, Nina; Kuester, Robert; Scott, Aaron; Khreiss, Mohammad; Frankel, Timothy; Merchant, Juanita; Jenkins, Brendan J; Wang, Jiang; Shroff, Rachna T; Ahmad, Syed A; Zavros, Yana 2020. Murine- and Human-Derived Autologous Organoid/Immune Cell Co-Cultures as Pre-Clinical Models of Pancreatic Ductal Adenocarcinoma. Cancers, 12 12, Kumar, Sudhir; Verma, Alok K; Rani, Richa; Sharma, Akanksha; Wang, Jiang; Shah, Shimul A; Behari, Jaideep; Salazar Gonzalez, Rosa; Kohli, Rohit; Gandhi, Chandrashekhar R 2020. Hepatic Deficiency of Augmenter of Liver Regeneration Predisposes to Nonalcoholic Steatohepatitis and Fibrosis. Hepatology (Baltimore, Md.), 72 5, 1586-1604Sharma, Akanksha; Verma, Alok K; Kofron, Matthew; Kudira, Ramesh; Miethke, Alexander; Wu, Tong; Wang, Jiang; Gandhi, Chandrashekhar R 2020. Lipopolysaccharide Reverses Hepatic Stellate Cell Activation Through Modulation of cMyb, Small Mothers Against Decapentaplegic, and CCAAT/Enhancer-Binding Protein C/EBP Transcription Factors. Hepatology (Baltimore, Md.), 72 5, 1800-1818Zafereo, Mark; McIver, Bryan; Vargas-Salas, Sergio; Domínguez, José Miguel; Steward, David L; Holsinger, F Christopher; Kandil, Emad; Williams, Michelle; Cruz, Francisco; Loyola, Soledad; Solar, Antonieta; Roa, Juan Carlos; León, Augusto; Droppelman, Nicolás; Lobos, Maite; Arias, Tatiana; Kong, Christina S; Busaidy, Naifa; Grubbs, Elizabeth G; Graham, Paul; Stewart, John; Tang, Alice; Wang, Jiang; Orloff, Lisa; Henríquez, Marcela; Lagos, Marcela; Osorio, Miren; Schachter, Dina; Franco, Carmen; Medina, Francisco; Wohllk, Nelson; Diaz, René E; Veliz, Jesús; Horvath, Eleonora; Tala, Hernán; Pineda, Pedro; Arroyo, Patricia; Vasquez, Félix; Traipe, Eufrosina; Marín, Luis; Miranda, Giovanna; Bruce, Elsa; Bracamonte, Milagros; Mena, Natalia; González, Hernán E 2020. A Thyroid Genetic Classifier Correctly Predicts Benign Nodules with Indeterminate Cytology: Two Independent, Multicenter, Prospective Validation Trials. Thyroid : official journal of the American Thyroid Association, 30 5, 704-712Ge, Chunmin; Vilfranc, Chrystelle L; Che, Lixiao; Pandita, Raj K; Hambarde, Shashank; Andreassen, Paul R; Niu, Liang; Olowokure, Olugbenga; Shah, Shimul; Waltz, Susan E; Zou, Lee; Wang, Jiang; Pandita, Tej K; Du, Chunying 2019. The BRUCE-ATR Signaling Axis Is Required for Accurate DNA Replication and Suppression of Liver Cancer Development. Hepatology (Baltimore, Md.), 69 6, 2608-2622Holokai, Loryn; Chakrabarti, Jayati; Broda, Taylor; Chang, Julie; Hawkins, Jennifer A; Sundaram, Nambirajan; Wroblewski, Lydia E; Peek, Richard M; Wang, Jiang; Helmrath, Michael; Wells, James M; Zavros, Yana 2019. Increased Programmed Death-Ligand 1 is an Early Epithelial Cell Response to Helicobacter pylori Infection. PLoS pathogens, 15 1, e1007468Khanal, Tilak; Leung, Yuet-Kin; Jiang, Wang; Timchenko, Nicolai; Ho, Shuk-Mei; Kim, Kyounghyun 2019. NR2E3 is a key component in p53 activation by regulating a long noncoding RNA DINO in acute liver injuries. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33 7, 8335-8348Morris, Mackenzie C; Dhar, Vikrom K; Stevenson, Megan A; Winer, Leah K; Lee, Tiffany C; Wang, Jiang; Ahmad, Syed A; Patel, Sameer H; Sussman, Jeffrey J; Abbott, Daniel E 2019. Adjuvant Hyperthermic Intraperitoneal Chemotherapy (HIPEC) for patients at High-Risk of Peritoneal Metastases. Surgical oncology, 31 , 33-37Steele, Nina G; Chakrabarti, Jayati; Wang, Jiang; Biesiada, Jacek; Holokai, Loryn; Chang, Julie; Nowacki, Lauren M; Hawkins, Jennifer; Mahe, Maxime; Sundaram, Nambirajan; Shroyer, Noah; Medvedovic, Mario; Helmrath, Michael; Ahmad, Syed; Zavros, Yana 2019. An Organoid-Based Preclinical Model of Human Gastric Cancer. Cellular and molecular gastroenterology and hepatology, 7 1, 161-184Beckmann, Nadine; Kadow, Stephanie; Schumacher, Fabian; Göthert, Joachim R; Kesper, Stefanie; Draeger, Annette; Schulz-Schaeffer, Walter J; Wang, Jiang; Becker, Jan U; Kramer, Melanie; Kühn, Claudine; Kleuser, Burkhard; Becker, Katrin Anne; Gulbins, Erich; Carpinteiro, Alexander 2018. Pathological manifestations of Farber disease in a new mouse model. Biological chemistry, 399 10, 1183-1202Chakrabarti, Jayati; Holokai, Loryn; Syu, LiJyun; Steele, Nina G; Chang, Julie; Wang, Jiang; Ahmed, Syed; Dlugosz, Andrzej; Zavros, Yana 2018. Hedgehog signaling induces PD-L1 expression and tumor cell proliferation in gastric cancer. Oncotarget, 9 100, 37439-37457Eldessouki, Ihab; Gaber, Ola; Namad, Tariq; Wang, Jiang; Morris, John C; Abdel Karim, Nagla 2018. Small or Non-Small Cell Lung Cancer Based Therapy for Treatment of Large Cell Neuroendocrine Cancer of The Lung? University of Cincinnati Experience. Journal of oncology, 2018 , 9761826Eldessouki, Ihab; Gaber, Ola; Riaz, Muhammad K; Wang, Jiang; Abdel Karim, Nagla 2018. Clinical Presentation and Treatment Options for Clear Cell Lung Cancer: University of Cincinnati A Case Series and Literature Review of Clear Cell Lung Cancer Asian Pacific journal of cancer prevention : APJCP, 19 9, 2373-2376Karim, Nagla Abdel; Schuster, James; Eldessouki, Ihab; Gaber, Ola; Namad, Tariq; Wang, Jiang; Xie, Changchun; Morris, John C 2018. Pulmonary sarcomatoid carcinoma: University of Cincinnati experience. Oncotarget, 9 3, 4102-4108Yang, Yongguang; Leonard, Marissa; Zhang, Yijuan; Zhao, Dan; Mahmoud, Charif; Khan, Shugufta; Wang, Jiang; Lower, Elyse E; Zhang, Xiaoting 2018. HER2-Driven Breast Tumorigenesis Relies upon Interactions of the Estrogen Receptor with Coactivator MED1. Cancer research, 78 2, 422-435Balestra, Rick; Benzaquen, Sadia; Wang, Jiang 2017. Sarcoidosis-like Granulomatous Lung Reaction Associated with Anti-Programmed Death Receptor-1 Ligand Therapy. Annals of the American Thoracic Society, 14 2, 296-299Bertaux-Skeirik, Nina; Wunderlich, Mark; Teal, Emma; Chakrabarti, Jayati; Biesiada, Jacek; Mahe, Maxime; Sundaram, Nambirajan; Gabre, Joel; Hawkins, Jennifer; Jian, Gao; Engevik, Amy C; Yang, Li; Wang, Jiang; Goldenring, James R; Qualls, Joseph E; Medvedovic, Mario; Helmrath, Michael A; Diwan, Tayyab; Mulloy, James C; Zavros, Yana 2017. CD44 variant isoform 9 emerges in response to injury and contributes to the regeneration of the gastric epithelium. The Journal of pathology, 242 4, 463-475Karim, Nagla A; Eldessouki, Ihab; Yellu, Mahendar; Namad, Tariq; Wang, Jiang; Gaber, Ola 2017. A Case Study in Advanced Lung Cancer Patients with Vimentin Over Expression. Clinical laboratory, 63 10, 1575-1579Khanal, Tilak; Choi, Kwangmin; Leung, Yuet-Kin; Wang, Jiang; Kim, Dasom; Janakiram, Vinothini; Cho, Sung-Gook; Puga, Alvaro; Ho, Shuk-Mei; Kim, Kyounghyun 2017. Loss of NR2E3 represses AHR by LSD1 reprogramming, is associated with poor prognosis in liver cancer. Scientific reports, 7 1, 10662Kumar, Sudhir; Wang, Jiang; Shanmukhappa, Shiva Kumar; Gandhi, Chandrashekhar R 2017. Toll-Like Receptor 4-Independent Carbon Tetrachloride-Induced Fibrosis and Lipopolysaccharide-Induced Acute Liver Injury in Mice: Role of Hepatic Stellate Cells. The American journal of pathology, 187 6, 1356-1367Kumar, Sudhir; Wang, Jiang; Thomson, Angus W; Gandhi, Chandrashekhar R 2017. Hepatic stellate cells increase the immunosuppressive function of natural Foxp3+ regulatory T cells via IDO-induced AhR activation. Journal of leukocyte biology, 101 2, 429-438Rani, Richa; Tandon, Ashish; Wang, Jiang; Kumar, Sudhir; Gandhi, Chandrashekhar R 2017. Stellate Cells Orchestrate Concanavalin A-Induced Acute Liver Damage. The American journal of pathology, 187 9, 2008-2019Xia, Brent T; Fu, Baojin; Wang, Jiang; Kim, Young; Ahmad, S Ameen; Dhar, Vikrom K; Levinsky, Nick C; Hanseman, Dennis J; Habib, David A; Wilson, Gregory C; Smith, Milton; Olowokure, Olugbenga O; Kharofa, Jordan; Al Humaidi, Ali H; Choe, Kyuran A; Abbott, Daniel E; Ahmad, Syed A 2017. Does radiologic response correlate to pathologic response in patients undergoing neoadjuvant therapy for borderline resectable pancreatic malignancy? Journal of surgical oncology, 115 4, 376-383Agarwal, Rishi; Wang, Jiang; Wilson, Keith; Barrett, William; Morris, John C 2016. Response to Targeted Therapy in BRAF Mutant Anaplastic Thyroid Cancer. Journal of the National Comprehensive Cancer Network : JNCCN, 14 10, 1203-1207Aihara, Eitaro; Matthis, Andrea L; Karns, Rebekah A; Engevik, Kristen A; Jiang, Peihua; Wang, Jiang; Yacyshyn, Bruce R; Montrose, Marshall H 2016. Epithelial Regeneration After Gastric Ulceration Causes Prolonged Cell-Type Alterations. Cellular and molecular gastroenterology and hepatology, 2 5, 625-647Kumar, Sudhir; Wang, Jiang; Rani, Richa; Gandhi, Chandrashekhar R 2016. Hepatic Deficiency of Augmenter of Liver Regeneration Exacerbates Alcohol-Induced Liver Injury and Promotes Fibrosis in Mice. PloS one, 11 1, e0147864Li, Chenggang; Li, Na; Liu, Xiaolei; Zhang, Erik Y; Sun, Yang; Masuda, Kouhei; Li, Jing; Sun, Julia; Morrison, Tasha; Li, Xiangke; Chen, Yuanguang; Wang, Jiang; Karim, Nagla A; Zhang, Yi; Blenis, John; Reginato, Mauricio J; Henske, Elizabeth P; Yu, Jane J 2016. Proapoptotic protein Bim attenuates estrogen-enhanced survival in lymphangioleiomyomatosis. JCI insight, 1 19, e86629Orienti, Isabella; Falconi, Mirella; Teti, Gabriella; Currier, Mark A; Wang, Jiang; Phelps, Mitch; Cripe, Timothy P 2016. Preparation and Evaluation of a Novel Class of Amphiphilic Amines as Antitumor Agents and Nanocarriers for Bioactive Molecules. Pharmaceutical research, 33 11, 2722-35Paterno, Flavio; Girnita, Alin; Brailey, Paul; Witte, David; Wang, Jiang; Cuffy, Madison C; Diwan, Tayyab; Tremblay, Simon; Revollo, Jane Y; Alloway, Rita R; Schoech, Michael R; Anwar, Nadim; Shah, Shimul A; Woodle, Steve E 2016. Successful Simultaneous Liver-Kidney Transplantation in the Presence of Multiple High-Titered Class I and II Antidonor HLA Antibodies. Transplantation direct, 2 12, e121Engevik, Melinda A; Engevik, Kristen A; Yacyshyn, Mary Beth; Wang, Jiang; Hassett, Daniel J; Darien, Benjamin; Yacyshyn, Bruce R; Worrell, Roger T 2015. Human Clostridium difficile infection: inhibition of NHE3 and microbiota profile. American journal of physiology. Gastrointestinal and liver physiology, 308 6, G497-509Engevik, Melinda A; Yacyshyn, Mary Beth; Engevik, Kristen A; Wang, Jiang; Darien, Benjamin; Hassett, Daniel J; Yacyshyn, Bruce R; Worrell, Roger T 2015. Human Clostridium difficile infection: altered mucus production and composition. American journal of physiology. Gastrointestinal and liver physiology, 308 6, G510-24Gandhi, Chandrashekhar R; Chaillet, J Richard; Nalesnik, Michael A; Kumar, Sudhir; Dangi, Anil; Demetris, A Jake; Ferrell, Robert; Wu, Tong; Divanovic, Senad; Stankeiwicz, Traci; Shaffer, Benjamin; Stolz, Donna B; Harvey, Stephen A K; Wang, Jiang; Starzl, Thomas E 2015. Liver-specific deletion of augmenter of liver regeneration accelerates development of steatohepatitis and hepatocellular carcinoma in mice. Gastroenterology, 148 2, 379-391.e4Garrison, Jason B; Ge, Chunmin; Che, Lixiao; Pullum, Derek A; Peng, Guang; Khan, Sohaib; Ben-Jonathan, Nira; Wang, Jiang; Du, Chunying 2015. Knockdown of the Inhibitor of Apoptosis BRUCE Sensitizes Resistant Breast Cancer Cells to Chemotherapeutic Agents. Journal of cancer science & therapy, 7 4, 121-126Quillin, Ralph C; Wilson, Gregory C; Nojima, Hiroyuki; Freeman, Christopher M; Wang, Jiang; Schuster, Rebecca M; Blanchard, John A; Edwards, Michael J; Gandhi, Chandrashekhar R; Gulbins, Erich; Lentsch, Alex B 2015. Inhibition of acidic sphingomyelinase reduces established hepatic fibrosis in mice. Hepatology research : the official journal of the Japan Society of Hepatology, 45 3, 305-14Wang, Yuan-Liang; Overstreet, Anne-Marie; Chen, Min-Shan; Wang, Jiang; Zhao, Hua-Jun; Ho, Po-Chun; Smith, Molly; Wang, Shao-Chun 2015. Combined inhibition of EGFR and c-ABL suppresses the growth of triple-negative breast cancer growth through inhibition of HOTAIR. Oncotarget, 6 13, 11150-61Ahmad, Nisar; Adams, Denise M; Wang, Jiang; Prakash, Rajan; Karim, Nagla Abdel 2014. Hepatic epithelioid hemangioendothelioma in a patient with hemochromatosis. Journal of the National Comprehensive Cancer Network : JNCCN, 12 9, 1203-7Dong, Zhongyun; Meller, Jaroslaw; Succop, Paul; Wang, Jiang; Wikenheiser-Brokamp, Kathryn; Starnes, Sandra; Lu, Shan 2014. Secretory phospholipase A2-IIa upregulates HER/HER2-elicited signaling in lung cancer cells. International journal of oncology, 45 3, 978-84Fisher, Alexander V; Sutton, Jeffrey M; Wilson, Gregory C; Hanseman, Dennis J; Abbott, Daniel E; Smith, Milton T; Schmulewitz, Nathan; Choe, Kyran A; Wang, Jiang; Sussman, Jeffrey J; Ahmad, Syed A 2014. High readmission rates after surgery for chronic pancreatitis. Surgery, 156 4, 787-94Lam, Hung-Ming; Ouyang, Bin; Chen, Jing; Ying, Jun; Wang, Jiang; Wu, Chin-Lee; Jia, Li; Medvedovic, Mario; Vessella, Robert L; Ho, Shuk-Mei 2014. Targeting GPR30 with G-1: a new therapeutic target for castration-resistant prostate cancer. Endocrine-related cancer, 21 6, 903-14Lutz, Eric R; Wu, Annie A; Bigelow, Elaine; Sharma, Rajni; Mo, Guanglan; Soares, Kevin; Solt, Sara; Dorman, Alvin; Wamwea, Anthony; Yager, Allison; Laheru, Daniel; Wolfgang, Christopher L; Wang, Jiang; Hruban, Ralph H; Anders, Robert A; Jaffee, Elizabeth M; Zheng, Lei 2014. Immunotherapy converts nonimmunogenic pancreatic tumors into immunogenic foci of immune regulation. Cancer immunology research, 2 7, 616-31Namad, Tariq; Wang, Jiang; Tilton, Annemarie; Abdel Karim, Nagla 2014. Bilateral choroidal metastasis from non-small cell lung cancer. Case reports in oncological medicine, 2014 , 858265Taftaf, Rokana; Starnes, Sandra; Wang, Jiang; Shipley, Ralph; Namad, Tariq; Khaled, Rana; Abdel Karim, Nagla 2014. Benign metastasizing leiomyoma: a rare type of lung metastases-two case reports and review of the literature. Case reports in oncological medicine, 2014 , 842801Bahassi, El Mustapha; Li, Ya-Qin; Wise-Draper, Trisha M; Deng, Li; Wang, Jiang; Darnell, Colleen N; Wilson, Keith M; Wells, Susanne I; Stambrook, Peter J; Rixe, Olivier 2013. A patient-derived somatic mutation in the epidermal growth factor receptor ligand-binding domain confers increased sensitivity to cetuximab in head and neck cancer. European journal of cancer (Oxford, England : 1990), 49 10, 2345-55Namad, Tariq; Wang, Jiang; Shipley, Ralph; Abdel Karim, Nagla 2013. Thyroid metastasis from nonsmall cell lung cancer. Case reports in oncological medicine, 2013 , 208213Shen, Ling; Xiong, Ye; Wang, David Q-H; Howles, Philip; Basford, Joshua E; Wang, Jiang; Xiong, Yu Qing; Hui, David Y; Woods, Stephen C; Liu, Min 2013. Ginsenoside Rb1 reduces fatty liver by activating AMP-activated protein kinase in obese rats. Journal of lipid research, 54 5, 1430-8Cui J, Germer K, Wu T, Wang J, Luo J, Wang SC, Wang Q, Zhang X 2012. Crosstalk Between HER2 and MED1 Regulates Tamoxifen Resistance of Human Breast Cancer Cells Cancer Res, 2012 Sep 10 , [Epub ahead of print]Cui, Jiajun; Germer, Katherine; Wu, Tianying; Wang, Jiang; Luo, Jia; Wang, Shao-chun; Wang, Qianben; Zhang, Xiaoting 2012. Cross-talk between HER2 and MED1 regulates tamoxifen resistance of human breast cancer cells. Cancer research, 72 21, 5625-34Hung-Ming Lam, Suresh Babu, Jiang Wang, Yong Yuan, Ying-Wai Lam, Shuk-Mei Ho, Yuet-Kin Leung 2012. Phosphorylation of human estrogen receptor-beta at serine 105 inhibits breast cancer cell migration and invasion Mol Cell Endocrinal, 358 1, 27-35Lam, Hung-Ming; Suresh Babu, C V; Wang, Jiang; Yuan, Yong; Lam, Ying-Wai; Ho, Shuk-Mei; Leung, Yuet-Kin 2012. Phosphorylation of human estrogen receptor-beta at serine 105 inhibits breast cancer cell migration and invasion. Molecular and cellular endocrinology, 358 1, 27-35Liu, Pengyuan; Morrison, Carl; Wang, Liang; Xiong, Donghai; Vedell, Peter; Cui, Peng; Hua, Xing; Ding, Feng; Lu, Yan; James, Michael; Ebben, John D; Xu, Haiming; Adjei, Alex A; Head, Karen; Andrae, Jaime W; Tschannen, Michael R; Jacob, Howard; Pan, Jing; Zhang, Qi; Van den Bergh, Francoise; Xiao, Haijie; Lo, Ken C; Patel, Jigar; Richmond, Todd; Watt, Mary-Anne; Albert, Thomas; Selzer, Rebecca; Anderson, Marshall; Wang, Jiang; Wang, Yian; Starnes, Sandra; Yang, Ping; You, Ming 2012. Identification of somatic mutations in non-small cell lung carcinomas using whole-exome sequencing. Carcinogenesis, 33 7, 1270-6Pengyuan Liu, Carl Morrison, Liang Wang, Donghai Xiong, Peter Verdell, Peng Cui, Feng Ding, Yan Lu, Karen Head, Jaime W. Andrae, Michael R. Tschannen, Howard Jacob, Jing Pan, Qi Zhang, Francoise Van den Bergh, Haijie Xiao, Ken C. Lo, Jigar Patel, Todd Richmond, Mary-Anne Watt, Thomas Albert, Rebecca Selzer, Marshall Anderson, Jiang Wang, Yian Wang, Sandra Starnes, Ping Yang, Ming You 2012. Identification of somatic mutations in non-small cell lung carcinoma using whole –exome sequencing Carcinogenesis, 33 7, 1270-6Raza, Ali; Yousaf, Wajeeha; Ahmed, Kashif; Muntel, Emily; Wang, Jiang; Rood, Richard P 2012. Protein-Losing Enteropathy in a Post-partum Female Secondary to Metastatic Melanoma of the Gut: Report of a Case. Journal of gastrointestinal cancer, 43 Suppl 1 , S148-50Starnes SL, Pathrose P, Wang J, Succop P, Morris JC, Bridges J, Kupert EY, Anderson M 2012. Clinical and Molecular Predictors of Recurrence in Stage I Non-Small Cell Lung Cancer Ann Thorac Surg, 93 5, 1606-12Starnes, Sandra L; Pathrose, Peterson; Wang, Jiang; Succop, Paul; Morris, John C; Bridges, James; Kupert, Elena Y; Anderson, Marshall 2012. Clinical and molecular predictors of recurrence in stage I non-small cell lung cancer. The Annals of thoracic surgery, 93 5, 1606-12Zahedi K, Barone SL, Xu J, Steinbergs N, Schuster R, Lentsch AB, Amlal H, Wang J, Casero RA Jr, Soleimani M 2012. Hepatocyte specific ablation of spermine/spermidine-N1-acetyltransferase (SSAT) gene reduces the severity of CCl4-induced acute liver injury Am J Physiol Gastrointest Liver Physiol, 303 5, G546-60Zahedi, Kamyar; Barone, Sharon L; Xu, Jie; Steinbergs, Nora; Schuster, Rebecca; Lentsch, Alex B; Amlal, Hassane; Wang, Jiang; Casero, Robert A; Soleimani, Manoocher 2012. Hepatocyte-specific ablation of spermine/spermidine-N1-acetyltransferase gene reduces the severity of CCl4-induced acute liver injury. American journal of physiology. Gastrointestinal and liver physiology, 303 5, G546-60Dong, Zhongyun; Liu, Yin; Levin, Linda; Oleksowicz, Leslie; Wang, Jiang; Lu, Shan 2011. Vav3 oncogene is involved in regulation of secretory phospholipase A2-IIa expression in prostate cancer Oncology reports, 25 6, 1511-6Elena Kupert, Marshall Anderson, Yin Liu, Paul Succop, Linda Levin, Jiang Wang, Kathryn Wikenheiser-brokamp, Pingping Chen, Susan Pinney, Trudy Macdonald, Zhongyun Dong, Sandra Starnes, and Shan Lu 2011. Plasma Secretory Phospholipase A2-IIa as a Potential Biomarker for Lung Cancer BMC Cancer, 11 1, 513 Kupert, Elena; Anderson, Marshall; Liu, Yin; Succop, Paul; Levin, Linda; Wang, Jiang; Wikenheiser-brokamp, Kathryn; Chen, Pingping; Pinney, Susan M; Macdonald, Trudy; Dong, Zhongyun; Starnes, Sandra; Lu, Shan 2011. Plasma secretory phospholipase A2-IIa as a potential biomarker for lung cancer in patients with solitary pulmonary nodules. BMC cancer, 11 , 513Navaneethan, Udayakumar; Lancaster, Elisha; Venkatesh, Preethi Gk; Wang, Jiang; Neff1, Guy W 2011. 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Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 24 30, 4922-7Xu, Meifeng; Wani, Maqsood; Dai, Yan-Shan; Wang, Jiang; Yan, Mei; Ayub, Ahmar; Ashraf, Muhammad 2004. Differentiation of bone marrow stromal cells into the cardiac phenotype requires intercellular communication with myocytes. Circulation, 110 17, 2658-65Fenoglio-Preiser CM, Wang J, Stemmermann GN, Noffsinger A. 2003. TP53 and gastric carcinoma: A review Hum Mutat, 21 3, 258-270Clements, Wilson M; Wang, Jiang; Sarnaik, Amod; Kim, On Ja; MacDonald, Jack; Fenoglio-Preiser, Cecilia; Groden, Joanna; Lowy, Andrew M 2002. beta-Catenin mutation is a frequent cause of Wnt pathway activation in gastric cancer Cancer research, 62 12, 3503-6Shepherd T, Tolbert D, Benedetti J, Macdonald JS, Wiest J, DeVoe G, Jiang Wang, Noffsinger A, Stemmermann GN, Fenoglio-Preiser CM 2000. 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Microsatellite instability as a predictor of survival in head and neck cancer -- is there a link with colon cancer? ORL, 65 4, 193-8
Peer Reviewed Publications Rani, Richa; Sharma, Akanksha; Wang, Jiang; Kumar, Sudhir; Polaki, Usha S; Gandhi, Chandrashekhar R 2022. Endotoxin-Stimulated Hepatic Stellate Cells Augment Acetaminophen-Induced Hepatocyte Injury. The American journal of pathology, 192 3, 518-535Chakrabarti, Jayati; Koh, Vivien; Steele, Nina; Hawkins, Jennifer; Ito, Yoshiaki; Merchant, Juanita L; Wang, Jiang; Helmrath, Michael A; Ahmad, Syed A; So, Jimmy Bok Yan; Yong, Wei Peng; Zavros, Yana 2021. Disruption of Her2-Induced PD-L1 Inhibits Tumor Cell Immune Evasion in Patient-Derived Gastric Cancer Organoids. Cancers, 13 24, Khawar, Muhammad Umair; Tiwana, Maida; Sengupta, Ruchira; Wang, Jiang; Indihar, Veronica 2021. The reverse halo sign and spontaneous pneumothorax due to pulmonary mucormycosis. Respirology case reports, 9 3, e00712Koh, Vivien; Chakrabarti, Jayati; Torvund, Meaghan; Steele, Nina; Hawkins, Jennifer A; Ito, Yoshiaki; Wang, Jiang; Helmrath, Michael A; Merchant, Juanita L; Ahmed, Syed A; Shabbir, Asim; Yan So, Jimmy Bok; Yong, Wei Peng; Zavros, Yana 2021. Hedgehog transcriptional effector GLI mediates mTOR-Induced PD-L1 expression in gastric cancer organoids. Cancer letters, 518 , 59-71Lindquist, Diana M; Fugate, Elizabeth M; Wang, Jiang; Sharma, Akanksha; Gandhi, Chandrashekhar R; Dillman, Jonathan R 2021. MRI Measures of Murine Liver Fibrosis. Journal of magnetic resonance imaging : JMRI, 54 3, 739-749Vilfranc, Chrystelle L; Che, Li-Xiao; Patra, Krushna C; Niu, Liang; Olowokure, Olugbenga; Wang, Jiang; Shah, Shimul A; Du, Chun-Ying 2021. BIR repeat-containing ubiquitin conjugating enzyme (BRUCE) regulation of ?-catenin signaling in the progression of drug-induced hepatic fibrosis and carcinogenesis. World journal of hepatology, 13 3, 343-361Yang, Yongguang; Leonard, Marissa; Luo, Zhenhua; Yeo, Syn; Bick, Gregory; Hao, Mingang; Cai, Chunmiao; Charif, Mahmoud; Wang, Jiang; Guan, Jun-Lin; Lower, Elyse E; Zhang, Xiaoting 2021. Functional cooperation between co-amplified genes promotes aggressive phenotypes of HER2-positive breast cancer. Cell reports, 34 10, 108822Holokai, Loryn; Chakrabarti, Jayati; Lundy, Joanne; Croagh, Daniel; Adhikary, Pritha; Richards, Scott S; Woodson, Chantal; Steele, Nina; Kuester, Robert; Scott, Aaron; Khreiss, Mohammad; Frankel, Timothy; Merchant, Juanita; Jenkins, Brendan J; Wang, Jiang; Shroff, Rachna T; Ahmad, Syed A; Zavros, Yana 2020. Murine- and Human-Derived Autologous Organoid/Immune Cell Co-Cultures as Pre-Clinical Models of Pancreatic Ductal Adenocarcinoma. Cancers, 12 12, Kumar, Sudhir; Verma, Alok K; Rani, Richa; Sharma, Akanksha; Wang, Jiang; Shah, Shimul A; Behari, Jaideep; Salazar Gonzalez, Rosa; Kohli, Rohit; Gandhi, Chandrashekhar R 2020. Hepatic Deficiency of Augmenter of Liver Regeneration Predisposes to Nonalcoholic Steatohepatitis and Fibrosis. Hepatology (Baltimore, Md.), 72 5, 1586-1604Sharma, Akanksha; Verma, Alok K; Kofron, Matthew; Kudira, Ramesh; Miethke, Alexander; Wu, Tong; Wang, Jiang; Gandhi, Chandrashekhar R 2020. Lipopolysaccharide Reverses Hepatic Stellate Cell Activation Through Modulation of cMyb, Small Mothers Against Decapentaplegic, and CCAAT/Enhancer-Binding Protein C/EBP Transcription Factors. Hepatology (Baltimore, Md.), 72 5, 1800-1818Zafereo, Mark; McIver, Bryan; Vargas-Salas, Sergio; Domínguez, José Miguel; Steward, David L; Holsinger, F Christopher; Kandil, Emad; Williams, Michelle; Cruz, Francisco; Loyola, Soledad; Solar, Antonieta; Roa, Juan Carlos; León, Augusto; Droppelman, Nicolás; Lobos, Maite; Arias, Tatiana; Kong, Christina S; Busaidy, Naifa; Grubbs, Elizabeth G; Graham, Paul; Stewart, John; Tang, Alice; Wang, Jiang; Orloff, Lisa; Henríquez, Marcela; Lagos, Marcela; Osorio, Miren; Schachter, Dina; Franco, Carmen; Medina, Francisco; Wohllk, Nelson; Diaz, René E; Veliz, Jesús; Horvath, Eleonora; Tala, Hernán; Pineda, Pedro; Arroyo, Patricia; Vasquez, Félix; Traipe, Eufrosina; Marín, Luis; Miranda, Giovanna; Bruce, Elsa; Bracamonte, Milagros; Mena, Natalia; González, Hernán E 2020. A Thyroid Genetic Classifier Correctly Predicts Benign Nodules with Indeterminate Cytology: Two Independent, Multicenter, Prospective Validation Trials. Thyroid : official journal of the American Thyroid Association, 30 5, 704-712Ge, Chunmin; Vilfranc, Chrystelle L; Che, Lixiao; Pandita, Raj K; Hambarde, Shashank; Andreassen, Paul R; Niu, Liang; Olowokure, Olugbenga; Shah, Shimul; Waltz, Susan E; Zou, Lee; Wang, Jiang; Pandita, Tej K; Du, Chunying 2019. The BRUCE-ATR Signaling Axis Is Required for Accurate DNA Replication and Suppression of Liver Cancer Development. Hepatology (Baltimore, Md.), 69 6, 2608-2622Holokai, Loryn; Chakrabarti, Jayati; Broda, Taylor; Chang, Julie; Hawkins, Jennifer A; Sundaram, Nambirajan; Wroblewski, Lydia E; Peek, Richard M; Wang, Jiang; Helmrath, Michael; Wells, James M; Zavros, Yana 2019. Increased Programmed Death-Ligand 1 is an Early Epithelial Cell Response to Helicobacter pylori Infection. PLoS pathogens, 15 1, e1007468Khanal, Tilak; Leung, Yuet-Kin; Jiang, Wang; Timchenko, Nicolai; Ho, Shuk-Mei; Kim, Kyounghyun 2019. NR2E3 is a key component in p53 activation by regulating a long noncoding RNA DINO in acute liver injuries. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33 7, 8335-8348Morris, Mackenzie C; Dhar, Vikrom K; Stevenson, Megan A; Winer, Leah K; Lee, Tiffany C; Wang, Jiang; Ahmad, Syed A; Patel, Sameer H; Sussman, Jeffrey J; Abbott, Daniel E 2019. Adjuvant Hyperthermic Intraperitoneal Chemotherapy (HIPEC) for patients at High-Risk of Peritoneal Metastases. Surgical oncology, 31 , 33-37Steele, Nina G; Chakrabarti, Jayati; Wang, Jiang; Biesiada, Jacek; Holokai, Loryn; Chang, Julie; Nowacki, Lauren M; Hawkins, Jennifer; Mahe, Maxime; Sundaram, Nambirajan; Shroyer, Noah; Medvedovic, Mario; Helmrath, Michael; Ahmad, Syed; Zavros, Yana 2019. An Organoid-Based Preclinical Model of Human Gastric Cancer. Cellular and molecular gastroenterology and hepatology, 7 1, 161-184Beckmann, Nadine; Kadow, Stephanie; Schumacher, Fabian; Göthert, Joachim R; Kesper, Stefanie; Draeger, Annette; Schulz-Schaeffer, Walter J; Wang, Jiang; Becker, Jan U; Kramer, Melanie; Kühn, Claudine; Kleuser, Burkhard; Becker, Katrin Anne; Gulbins, Erich; Carpinteiro, Alexander 2018. Pathological manifestations of Farber disease in a new mouse model. Biological chemistry, 399 10, 1183-1202Chakrabarti, Jayati; Holokai, Loryn; Syu, LiJyun; Steele, Nina G; Chang, Julie; Wang, Jiang; Ahmed, Syed; Dlugosz, Andrzej; Zavros, Yana 2018. Hedgehog signaling induces PD-L1 expression and tumor cell proliferation in gastric cancer. Oncotarget, 9 100, 37439-37457Eldessouki, Ihab; Gaber, Ola; Namad, Tariq; Wang, Jiang; Morris, John C; Abdel Karim, Nagla 2018. Small or Non-Small Cell Lung Cancer Based Therapy for Treatment of Large Cell Neuroendocrine Cancer of The Lung? University of Cincinnati Experience. Journal of oncology, 2018 , 9761826Eldessouki, Ihab; Gaber, Ola; Riaz, Muhammad K; Wang, Jiang; Abdel Karim, Nagla 2018. Clinical Presentation and Treatment Options for Clear Cell Lung Cancer: University of Cincinnati A Case Series and Literature Review of Clear Cell Lung Cancer Asian Pacific journal of cancer prevention : APJCP, 19 9, 2373-2376Karim, Nagla Abdel; Schuster, James; Eldessouki, Ihab; Gaber, Ola; Namad, Tariq; Wang, Jiang; Xie, Changchun; Morris, John C 2018. Pulmonary sarcomatoid carcinoma: University of Cincinnati experience. Oncotarget, 9 3, 4102-4108Yang, Yongguang; Leonard, Marissa; Zhang, Yijuan; Zhao, Dan; Mahmoud, Charif; Khan, Shugufta; Wang, Jiang; Lower, Elyse E; Zhang, Xiaoting 2018. HER2-Driven Breast Tumorigenesis Relies upon Interactions of the Estrogen Receptor with Coactivator MED1. Cancer research, 78 2, 422-435Balestra, Rick; Benzaquen, Sadia; Wang, Jiang 2017. Sarcoidosis-like Granulomatous Lung Reaction Associated with Anti-Programmed Death Receptor-1 Ligand Therapy. Annals of the American Thoracic Society, 14 2, 296-299Bertaux-Skeirik, Nina; Wunderlich, Mark; Teal, Emma; Chakrabarti, Jayati; Biesiada, Jacek; Mahe, Maxime; Sundaram, Nambirajan; Gabre, Joel; Hawkins, Jennifer; Jian, Gao; Engevik, Amy C; Yang, Li; Wang, Jiang; Goldenring, James R; Qualls, Joseph E; Medvedovic, Mario; Helmrath, Michael A; Diwan, Tayyab; Mulloy, James C; Zavros, Yana 2017. CD44 variant isoform 9 emerges in response to injury and contributes to the regeneration of the gastric epithelium. The Journal of pathology, 242 4, 463-475Karim, Nagla A; Eldessouki, Ihab; Yellu, Mahendar; Namad, Tariq; Wang, Jiang; Gaber, Ola 2017. A Case Study in Advanced Lung Cancer Patients with Vimentin Over Expression. Clinical laboratory, 63 10, 1575-1579Khanal, Tilak; Choi, Kwangmin; Leung, Yuet-Kin; Wang, Jiang; Kim, Dasom; Janakiram, Vinothini; Cho, Sung-Gook; Puga, Alvaro; Ho, Shuk-Mei; Kim, Kyounghyun 2017. Loss of NR2E3 represses AHR by LSD1 reprogramming, is associated with poor prognosis in liver cancer. Scientific reports, 7 1, 10662Kumar, Sudhir; Wang, Jiang; Shanmukhappa, Shiva Kumar; Gandhi, Chandrashekhar R 2017. Toll-Like Receptor 4-Independent Carbon Tetrachloride-Induced Fibrosis and Lipopolysaccharide-Induced Acute Liver Injury in Mice: Role of Hepatic Stellate Cells. The American journal of pathology, 187 6, 1356-1367Kumar, Sudhir; Wang, Jiang; Thomson, Angus W; Gandhi, Chandrashekhar R 2017. Hepatic stellate cells increase the immunosuppressive function of natural Foxp3+ regulatory T cells via IDO-induced AhR activation. Journal of leukocyte biology, 101 2, 429-438Rani, Richa; Tandon, Ashish; Wang, Jiang; Kumar, Sudhir; Gandhi, Chandrashekhar R 2017. Stellate Cells Orchestrate Concanavalin A-Induced Acute Liver Damage. The American journal of pathology, 187 9, 2008-2019Xia, Brent T; Fu, Baojin; Wang, Jiang; Kim, Young; Ahmad, S Ameen; Dhar, Vikrom K; Levinsky, Nick C; Hanseman, Dennis J; Habib, David A; Wilson, Gregory C; Smith, Milton; Olowokure, Olugbenga O; Kharofa, Jordan; Al Humaidi, Ali H; Choe, Kyuran A; Abbott, Daniel E; Ahmad, Syed A 2017. Does radiologic response correlate to pathologic response in patients undergoing neoadjuvant therapy for borderline resectable pancreatic malignancy? Journal of surgical oncology, 115 4, 376-383Agarwal, Rishi; Wang, Jiang; Wilson, Keith; Barrett, William; Morris, John C 2016. Response to Targeted Therapy in BRAF Mutant Anaplastic Thyroid Cancer. Journal of the National Comprehensive Cancer Network : JNCCN, 14 10, 1203-1207Aihara, Eitaro; Matthis, Andrea L; Karns, Rebekah A; Engevik, Kristen A; Jiang, Peihua; Wang, Jiang; Yacyshyn, Bruce R; Montrose, Marshall H 2016. Epithelial Regeneration After Gastric Ulceration Causes Prolonged Cell-Type Alterations. Cellular and molecular gastroenterology and hepatology, 2 5, 625-647Kumar, Sudhir; Wang, Jiang; Rani, Richa; Gandhi, Chandrashekhar R 2016. Hepatic Deficiency of Augmenter of Liver Regeneration Exacerbates Alcohol-Induced Liver Injury and Promotes Fibrosis in Mice. PloS one, 11 1, e0147864Li, Chenggang; Li, Na; Liu, Xiaolei; Zhang, Erik Y; Sun, Yang; Masuda, Kouhei; Li, Jing; Sun, Julia; Morrison, Tasha; Li, Xiangke; Chen, Yuanguang; Wang, Jiang; Karim, Nagla A; Zhang, Yi; Blenis, John; Reginato, Mauricio J; Henske, Elizabeth P; Yu, Jane J 2016. Proapoptotic protein Bim attenuates estrogen-enhanced survival in lymphangioleiomyomatosis. JCI insight, 1 19, e86629Orienti, Isabella; Falconi, Mirella; Teti, Gabriella; Currier, Mark A; Wang, Jiang; Phelps, Mitch; Cripe, Timothy P 2016. Preparation and Evaluation of a Novel Class of Amphiphilic Amines as Antitumor Agents and Nanocarriers for Bioactive Molecules. Pharmaceutical research, 33 11, 2722-35Paterno, Flavio; Girnita, Alin; Brailey, Paul; Witte, David; Wang, Jiang; Cuffy, Madison C; Diwan, Tayyab; Tremblay, Simon; Revollo, Jane Y; Alloway, Rita R; Schoech, Michael R; Anwar, Nadim; Shah, Shimul A; Woodle, Steve E 2016. Successful Simultaneous Liver-Kidney Transplantation in the Presence of Multiple High-Titered Class I and II Antidonor HLA Antibodies. Transplantation direct, 2 12, e121Engevik, Melinda A; Engevik, Kristen A; Yacyshyn, Mary Beth; Wang, Jiang; Hassett, Daniel J; Darien, Benjamin; Yacyshyn, Bruce R; Worrell, Roger T 2015. Human Clostridium difficile infection: inhibition of NHE3 and microbiota profile. American journal of physiology. Gastrointestinal and liver physiology, 308 6, G497-509Engevik, Melinda A; Yacyshyn, Mary Beth; Engevik, Kristen A; Wang, Jiang; Darien, Benjamin; Hassett, Daniel J; Yacyshyn, Bruce R; Worrell, Roger T 2015. Human Clostridium difficile infection: altered mucus production and composition. American journal of physiology. Gastrointestinal and liver physiology, 308 6, G510-24Gandhi, Chandrashekhar R; Chaillet, J Richard; Nalesnik, Michael A; Kumar, Sudhir; Dangi, Anil; Demetris, A Jake; Ferrell, Robert; Wu, Tong; Divanovic, Senad; Stankeiwicz, Traci; Shaffer, Benjamin; Stolz, Donna B; Harvey, Stephen A K; Wang, Jiang; Starzl, Thomas E 2015. Liver-specific deletion of augmenter of liver regeneration accelerates development of steatohepatitis and hepatocellular carcinoma in mice. Gastroenterology, 148 2, 379-391.e4Garrison, Jason B; Ge, Chunmin; Che, Lixiao; Pullum, Derek A; Peng, Guang; Khan, Sohaib; Ben-Jonathan, Nira; Wang, Jiang; Du, Chunying 2015. Knockdown of the Inhibitor of Apoptosis BRUCE Sensitizes Resistant Breast Cancer Cells to Chemotherapeutic Agents. Journal of cancer science & therapy, 7 4, 121-126Quillin, Ralph C; Wilson, Gregory C; Nojima, Hiroyuki; Freeman, Christopher M; Wang, Jiang; Schuster, Rebecca M; Blanchard, John A; Edwards, Michael J; Gandhi, Chandrashekhar R; Gulbins, Erich; Lentsch, Alex B 2015. Inhibition of acidic sphingomyelinase reduces established hepatic fibrosis in mice. Hepatology research : the official journal of the Japan Society of Hepatology, 45 3, 305-14Wang, Yuan-Liang; Overstreet, Anne-Marie; Chen, Min-Shan; Wang, Jiang; Zhao, Hua-Jun; Ho, Po-Chun; Smith, Molly; Wang, Shao-Chun 2015. Combined inhibition of EGFR and c-ABL suppresses the growth of triple-negative breast cancer growth through inhibition of HOTAIR. Oncotarget, 6 13, 11150-61Ahmad, Nisar; Adams, Denise M; Wang, Jiang; Prakash, Rajan; Karim, Nagla Abdel 2014. Hepatic epithelioid hemangioendothelioma in a patient with hemochromatosis. Journal of the National Comprehensive Cancer Network : JNCCN, 12 9, 1203-7Dong, Zhongyun; Meller, Jaroslaw; Succop, Paul; Wang, Jiang; Wikenheiser-Brokamp, Kathryn; Starnes, Sandra; Lu, Shan 2014. Secretory phospholipase A2-IIa upregulates HER/HER2-elicited signaling in lung cancer cells. International journal of oncology, 45 3, 978-84Fisher, Alexander V; Sutton, Jeffrey M; Wilson, Gregory C; Hanseman, Dennis J; Abbott, Daniel E; Smith, Milton T; Schmulewitz, Nathan; Choe, Kyran A; Wang, Jiang; Sussman, Jeffrey J; Ahmad, Syed A 2014. High readmission rates after surgery for chronic pancreatitis. Surgery, 156 4, 787-94Lam, Hung-Ming; Ouyang, Bin; Chen, Jing; Ying, Jun; Wang, Jiang; Wu, Chin-Lee; Jia, Li; Medvedovic, Mario; Vessella, Robert L; Ho, Shuk-Mei 2014. Targeting GPR30 with G-1: a new therapeutic target for castration-resistant prostate cancer. Endocrine-related cancer, 21 6, 903-14Lutz, Eric R; Wu, Annie A; Bigelow, Elaine; Sharma, Rajni; Mo, Guanglan; Soares, Kevin; Solt, Sara; Dorman, Alvin; Wamwea, Anthony; Yager, Allison; Laheru, Daniel; Wolfgang, Christopher L; Wang, Jiang; Hruban, Ralph H; Anders, Robert A; Jaffee, Elizabeth M; Zheng, Lei 2014. Immunotherapy converts nonimmunogenic pancreatic tumors into immunogenic foci of immune regulation. Cancer immunology research, 2 7, 616-31Namad, Tariq; Wang, Jiang; Tilton, Annemarie; Abdel Karim, Nagla 2014. Bilateral choroidal metastasis from non-small cell lung cancer. Case reports in oncological medicine, 2014 , 858265Taftaf, Rokana; Starnes, Sandra; Wang, Jiang; Shipley, Ralph; Namad, Tariq; Khaled, Rana; Abdel Karim, Nagla 2014. Benign metastasizing leiomyoma: a rare type of lung metastases-two case reports and review of the literature. Case reports in oncological medicine, 2014 , 842801Bahassi, El Mustapha; Li, Ya-Qin; Wise-Draper, Trisha M; Deng, Li; Wang, Jiang; Darnell, Colleen N; Wilson, Keith M; Wells, Susanne I; Stambrook, Peter J; Rixe, Olivier 2013. A patient-derived somatic mutation in the epidermal growth factor receptor ligand-binding domain confers increased sensitivity to cetuximab in head and neck cancer. European journal of cancer (Oxford, England : 1990), 49 10, 2345-55Namad, Tariq; Wang, Jiang; Shipley, Ralph; Abdel Karim, Nagla 2013. Thyroid metastasis from nonsmall cell lung cancer. Case reports in oncological medicine, 2013 , 208213Shen, Ling; Xiong, Ye; Wang, David Q-H; Howles, Philip; Basford, Joshua E; Wang, Jiang; Xiong, Yu Qing; Hui, David Y; Woods, Stephen C; Liu, Min 2013. Ginsenoside Rb1 reduces fatty liver by activating AMP-activated protein kinase in obese rats. Journal of lipid research, 54 5, 1430-8Cui J, Germer K, Wu T, Wang J, Luo J, Wang SC, Wang Q, Zhang X 2012. Crosstalk Between HER2 and MED1 Regulates Tamoxifen Resistance of Human Breast Cancer Cells Cancer Res, 2012 Sep 10 , [Epub ahead of print]Cui, Jiajun; Germer, Katherine; Wu, Tianying; Wang, Jiang; Luo, Jia; Wang, Shao-chun; Wang, Qianben; Zhang, Xiaoting 2012. Cross-talk between HER2 and MED1 regulates tamoxifen resistance of human breast cancer cells. Cancer research, 72 21, 5625-34Hung-Ming Lam, Suresh Babu, Jiang Wang, Yong Yuan, Ying-Wai Lam, Shuk-Mei Ho, Yuet-Kin Leung 2012. Phosphorylation of human estrogen receptor-beta at serine 105 inhibits breast cancer cell migration and invasion Mol Cell Endocrinal, 358 1, 27-35Lam, Hung-Ming; Suresh Babu, C V; Wang, Jiang; Yuan, Yong; Lam, Ying-Wai; Ho, Shuk-Mei; Leung, Yuet-Kin 2012. Phosphorylation of human estrogen receptor-beta at serine 105 inhibits breast cancer cell migration and invasion. Molecular and cellular endocrinology, 358 1, 27-35Liu, Pengyuan; Morrison, Carl; Wang, Liang; Xiong, Donghai; Vedell, Peter; Cui, Peng; Hua, Xing; Ding, Feng; Lu, Yan; James, Michael; Ebben, John D; Xu, Haiming; Adjei, Alex A; Head, Karen; Andrae, Jaime W; Tschannen, Michael R; Jacob, Howard; Pan, Jing; Zhang, Qi; Van den Bergh, Francoise; Xiao, Haijie; Lo, Ken C; Patel, Jigar; Richmond, Todd; Watt, Mary-Anne; Albert, Thomas; Selzer, Rebecca; Anderson, Marshall; Wang, Jiang; Wang, Yian; Starnes, Sandra; Yang, Ping; You, Ming 2012. Identification of somatic mutations in non-small cell lung carcinomas using whole-exome sequencing. Carcinogenesis, 33 7, 1270-6Pengyuan Liu, Carl Morrison, Liang Wang, Donghai Xiong, Peter Verdell, Peng Cui, Feng Ding, Yan Lu, Karen Head, Jaime W. Andrae, Michael R. Tschannen, Howard Jacob, Jing Pan, Qi Zhang, Francoise Van den Bergh, Haijie Xiao, Ken C. Lo, Jigar Patel, Todd Richmond, Mary-Anne Watt, Thomas Albert, Rebecca Selzer, Marshall Anderson, Jiang Wang, Yian Wang, Sandra Starnes, Ping Yang, Ming You 2012. Identification of somatic mutations in non-small cell lung carcinoma using whole –exome sequencing Carcinogenesis, 33 7, 1270-6Raza, Ali; Yousaf, Wajeeha; Ahmed, Kashif; Muntel, Emily; Wang, Jiang; Rood, Richard P 2012. Protein-Losing Enteropathy in a Post-partum Female Secondary to Metastatic Melanoma of the Gut: Report of a Case. Journal of gastrointestinal cancer, 43 Suppl 1 , S148-50Starnes SL, Pathrose P, Wang J, Succop P, Morris JC, Bridges J, Kupert EY, Anderson M 2012. Clinical and Molecular Predictors of Recurrence in Stage I Non-Small Cell Lung Cancer Ann Thorac Surg, 93 5, 1606-12Starnes, Sandra L; Pathrose, Peterson; Wang, Jiang; Succop, Paul; Morris, John C; Bridges, James; Kupert, Elena Y; Anderson, Marshall 2012. Clinical and molecular predictors of recurrence in stage I non-small cell lung cancer. The Annals of thoracic surgery, 93 5, 1606-12Zahedi K, Barone SL, Xu J, Steinbergs N, Schuster R, Lentsch AB, Amlal H, Wang J, Casero RA Jr, Soleimani M 2012. Hepatocyte specific ablation of spermine/spermidine-N1-acetyltransferase (SSAT) gene reduces the severity of CCl4-induced acute liver injury Am J Physiol Gastrointest Liver Physiol, 303 5, G546-60Zahedi, Kamyar; Barone, Sharon L; Xu, Jie; Steinbergs, Nora; Schuster, Rebecca; Lentsch, Alex B; Amlal, Hassane; Wang, Jiang; Casero, Robert A; Soleimani, Manoocher 2012. Hepatocyte-specific ablation of spermine/spermidine-N1-acetyltransferase gene reduces the severity of CCl4-induced acute liver injury. American journal of physiology. Gastrointestinal and liver physiology, 303 5, G546-60Dong, Zhongyun; Liu, Yin; Levin, Linda; Oleksowicz, Leslie; Wang, Jiang; Lu, Shan 2011. Vav3 oncogene is involved in regulation of secretory phospholipase A2-IIa expression in prostate cancer Oncology reports, 25 6, 1511-6Elena Kupert, Marshall Anderson, Yin Liu, Paul Succop, Linda Levin, Jiang Wang, Kathryn Wikenheiser-brokamp, Pingping Chen, Susan Pinney, Trudy Macdonald, Zhongyun Dong, Sandra Starnes, and Shan Lu 2011. Plasma Secretory Phospholipase A2-IIa as a Potential Biomarker for Lung Cancer BMC Cancer, 11 1, 513 Kupert, Elena; Anderson, Marshall; Liu, Yin; Succop, Paul; Levin, Linda; Wang, Jiang; Wikenheiser-brokamp, Kathryn; Chen, Pingping; Pinney, Susan M; Macdonald, Trudy; Dong, Zhongyun; Starnes, Sandra; Lu, Shan 2011. Plasma secretory phospholipase A2-IIa as a potential biomarker for lung cancer in patients with solitary pulmonary nodules. BMC cancer, 11 , 513Navaneethan, Udayakumar; Lancaster, Elisha; Venkatesh, Preethi Gk; Wang, Jiang; Neff1, Guy W 2011. Herpes simplex virus hepatitis - it's high time we consider empiric treatment Journal of gastrointestinal and liver diseases : JGLD, 20 1, 93-96Raza A, Yousaf W, Ahmed K, Muntel E, Wang J, Rood RP 2011. Protein-Losing Enteropathy in a Post-partum Female Secondary to Metastatic Melanoma of the Gut: Report of a Case J Gastrointest Cancer, October 18 , [Epub ahead of print]Tevar, Amit D; Clarke, Callisia N; Schuster, Rebecca; Wang, Jiang; Edwards, Michael J; Lentsch, Alex B 2011. The Effect of Hepatic Ischemia Reperfusion Injury in a Murine Model of Nonalcoholic Steatohepatitis J Surg Res, 169, e7-14Udayakumar Navaneethan, Elisha Lancaster, Jiang Wang, Guy W. Neff 2011. Herpes simplex hepatitis-It’s high time we consider empiric treatment J Gastrointestinal Liver Dis, 20 1, 93-96Ahmed, Kashif; Sussman, Jeffrey J; Wang, Jiang; Schmulewitz, Nathan 2010. 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