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Photo of Sarah J. Skuli, MD, PhD

Sarah J. Skuli, MD, PhD

Assistant Professor of Clinical

Internal Medicine | College of Medicine

Education/Credentials
  • MD: Johns Hopkins University School of Medicine
  • PhD: University of Toulouse (Cancer Biology)
  • BA: University of Pennsylvania (Biology, Psychology)
Board Certifications & Licenses

American Board of Internal Medicine (Hematology) (Certification Date: 2023-11-09)
American Board of Internal Medicine (Certification Date: 2021-08-16)

Languages

French

Specialties

Hematology
Internal Medicine

Contact Information

Clinical Interests

Hematology

Hematology and Oncology

Leukemia

Malignant Melanoma

Acute Lymphocytic Leukemia

Acute Myeloid Leukemia

Bone Marrow Cancers

Myeloma

Peer Reviewed Publications

Skuli S.; Matthews A.; Carroll M.; Lai C. 12-01-2024. A line in shifting sand: Can we define and target TP53 mutated MDS? Seminars in Hematology, 61 6, 449-456

Bosc C.; Broin N.; Fanjul M.; Saland E.; Farge T.; Courdy C.; Batut A.; Masoud R.; Larrue C.; Skuli S.; Espagnolle N.; Pagès J.C.; Carrier A.; Bost F.; Bertrand-Michel J.; Tamburini J.; Récher C.; Bertoli S.; Mansat-De Mas V.; Manenti S.; Sarry J.E.; Joffre C. 12-01-2020. Autophagy regulates fatty acid availability for oxidative phosphorylation through mitochondria-endop Nature Communications, 11 1,

Pottier A.; Park S.; Lee Y.; Liccardo F.; Yang H.; Park J.; Lorant A.; Schnekenburger M.; Brusa D.; Li V.; Valente S.; Mai A.; Skuli S.J.; Carroll M.; Boettcher S.; Sarry J.E.; Cerella C.; Morceau F.; Diederich M. 11-28-2025. TP53-agnostic lethality through combined pan-HDAC and CDK inhibition in acute myeloid leukemia Cancer Letters, 633 ,

Freyer C.W.; Bange E.M.; Skuli S.; Hsu M.; Lin J.; Cuker A.; Cohen A.D.; Garfall A. 11-01-2021. Carfilzomib-Induced Atypical Hemolytic Uremic Syndrome in a Patient With Heterozygous CFHR3/CFHR1 De Clinical Lymphoma Myeloma and Leukemia, 21 11, e845-e849

Skuli S.J.; Bakayoko A.; Kruidenier M.; Manning B.; Pammer P.; Salimov A.; Riley O.; Brake-Sillá G.; Dopkin D.; Bowman M.; Martinez-Gutierrez L.N.; Anderson C.C.; Reisz J.A.; Buono R.; Paul M.; Saland E.; Liccardo F.; DeVine A.; Wong S.; Xu J.P.; Nee E.; Hausler R.; Boettcher S.; Sebti S.M.; Lai C.; Maxwell K.N.; Sarry J.E.; Fruman D.A.; D’Alessandro A.; Mesaros C.; Keith B.; Simon M.C.; Sung P.J.; Wertheim G.; Skuli N.; Bowman R.L.; Matthews A.; Carroll M. 09-01-2025. Chemoresistance of TP53 mutant acute myeloid leukemia requires the mevalonate byproduct, geranylgera Leukemia, 39 9, 2087-2098

Senagolage M.D.; Blaylock H.Z.; Khan S.; Skuli S.J.; Carroll M.P.; McNerney M.E. 08-01-2025. NAMPT haploinsufficiency is a collateral lethal therapeutic vulnerability in high-risk myeloid malig Blood Neoplasia, 2 3,

Matthews A.H.; Perl A.E.; Luger S.M.; Gill S.I.; Lai C.; Porter D.L.; Skuli S.; Bruno X.J.; Carroll M.P.; Freyer C.W.; Carulli A.; Babushok D.V.; Frey N.V.; Hexner E.O.; Martin M.E.; McCurdy S.R.; Stadtmauer E.A.; Loren A.W.; Paralkar V.R.; Maillard I.P.; Pratz K.W. 08-01-2023. Real-world effectiveness of intensive chemotherapy with 7&3 versus venetoclax and hypomethylatin American Journal of Hematology, 98 8, 1254-1264

Zhang P.; Whipp E.C.; Skuli S.J.; Gharghabi M.; Saygin C.; Sher S.A.; Carroll M.; Pan X.; Eisenmann E.D.; Lai T.H.; Harrington B.K.; Chan W.K.; Youssef Y.; Chen B.; Penson A.; Lewis A.M.; Castro C.R.; Fox N.; Cihan A.; Le Luduec J.B.; DeWolf S.; Kauffman T.; Mims A.S.; Canfield D.; Phillips H.; Williams K.E.; Shaffer J.; Lozanski A.; Doong T.J.; Lozanski G.; Mao C.; Walker C.J.; Blachly J.S.; Daniyan A.F.; Alinari L.; Baiocchi R.A.; Yang Y.; Grieselhuber N.R.; Campbell M.J.; Baker S.D.; Blaser B.W.; Abdel-Wahab O.; Lapalombella R. 05-15-2025. TP53 mutations and TET2 deficiency cooperate to drive leukemogenesis and establish an immunosuppress Journal of Clinical Investigation, 135 10,

Skuli S.J.; Alomari S.; Gaitsch H.; Bakayoko A.; Skuli N.; Tyler B.M. 05-01-2022. Metformin and Cancer, an Ambiguanidous Relationship Pharmaceuticals, 15 5,

Skuli S.J.; Sheng J.Y.; Bantug E.T.; Zafman N.; Riley C.; Ruck J.M.; Smith K.C.; Snyder C.F.; Smith K.L.; Stearns V.; Wolff A.C. 02-15-2019. Survivorship care visits in a high-risk population of breast cancer survivors Breast Cancer Research and Treatment, 173 3, 701-708

Sheng J.Y.; Skuli S.J.; Thorner E.D.; Zafman N.; Riley C.D.; Ruck J.M.; Smith K.C.; Snyder C.; Smith K.L.; Stearns V.; Wolff A.C. 02-01-2022. Late effects in a high-risk population of breast cancer survivors Supportive Care in Cancer, 30 2, 1749-1757

Mahdavi L.; Alikarami F.; Goodrow H.; Lenard A.; Riedel S.S.; Libbrecht C.; Bowser I.; Tasian S.K.; Falkenstein C.D.; Manning B.; Skuli S.; Carroll M.P.; Wertheim G.; Cai S.F.; McGeehan G.; Yu S.; Shi J.; Xie H.M.; Bernt K.M. 01-01-2026. Upfront menin-inhibitor resistance in multiply pretreated leukemias Experimental Hematology, 153 ,

Boët E.; Saland E.; Skuli S.; Griessinger E.; Sarry J.E. 01-01-2024. Mitohormesis: The keystone of therapeutic resistance in cancer cells Comptes Rendus Biologies, 347 , 59-75

Matthews A.; Fenu E.; Skuli S.J.; Harris J.C.; Bagg A.; Lai C. 01-01-2024. Immunohistochemistry-based detection of TP53 mutations in acute myeloid leukemia: a promising high s Leukemia and Lymphoma, 65 7, 1012-1015