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Photo of Masato Nakafuku, MD,PhD

Masato Nakafuku, MD,PhD

Emeritus

Pediatrics | College of Medicine

Contact Information

Peer Reviewed Publications

Pei, Zhenglei; Wang, Bei; Chen, Gang; Nagao, Motoshi; Nakafuku, Masato; Campbell, Kenneth 2011. Homeobox genes Gsx1 and Gsx2 differentially regulate telencephalic progenitor maturation. Proceedings of the National Academy of Sciences of the United States of America, 108 4, 1675-80

Shereen, Ahmed; Nemkul, Niza; Yang, Dianer; Adhami, Faisal; Dunn, R Scott; Hazen, Missy L; Nakafuku, Masato; Ning, Gang; Lindquist, Diana M; Kuan, Chia-Yi 2011. Ex vivo diffusion tensor imaging and neuropathological correlation in a murine model of hypoxia-ischemia-induced thrombotic stroke. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 31 4, 1155-69

Zhong, Jingyang; Kim, Hyoung-Tai; Lyu, Jungmook; Yoshikawa, Kazuaki; Nakafuku, Masato; Lu, Wange 2011. The Wnt receptor Ryk controls specification of GABAergic neurons versus oligodendrocytes during telencephalon development. Development (Cambridge, England), 138 3, 409-19

Nagao, Motoshi; Campbell, Kenneth; Burns, Kevin; Kuan, Chia-Yi; Trumpp, Andreas; Nakafuku, Masato 2008. Coordinated control of self-renewal and differentiation of neural stem cells by Myc and the p19ARF-p53 pathway. The Journal of cell biology, 183 7, 1243-57

Nakafuku, Masato; Nagao, Motoshi; Grande, Andrew; Cancelliere, Alessandro 2008. Revisiting neural stem cell identity. Proceedings of the National Academy of Sciences of the United States of America, 105 3, 829-30

Sugimori, Michiya; Nagao, Motoshi; Parras, Carlos M; Nakatani, Hiroko; Lebel, Mélanie; Guillemot, François; Nakafuku, Masato 2008. Ascl1 is required for oligodendrocyte development in the spinal cord. Development (Cambridge, England), 135 7, 1271-81

Kim, Hyun-Jung; Sugimori, Michiya; Nakafuku, Masato; Svendsen, Clive N 2007. Control of neurogenesis and tyrosine hydroxylase expression in neural progenitor cells through bHLH proteins and Nurr1. Experimental neurology, 203 2, 394-405

Nagao, Motoshi; Sugimori, Michiya; Nakafuku, Masato 2007. Cross talk between notch and growth factor/cytokine signaling pathways in neural stem cells. Molecular and cellular biology, 27 11, 3982-94

Parras, Carlos M; Hunt, Charles; Sugimori, Michiya; Nakafuku, Masato; Rowitch, David; Guillemot, François 2007. The proneural gene Mash1 specifies an early population of telencephalic oligodendrocytes. The Journal of neuroscience : the official journal of the Society for Neuroscience, 27 16, 4233-42

Sugimori, Michiya; Nagao, Motoshi; Bertrand, Nicolas; Parras, Carlos M; Guillemot, François; Nakafuku, Masato 2007. Combinatorial actions of patterning and HLH transcription factors in the spatiotemporal control of neurogenesis and gliogenesis in the developing spinal cord. Development (Cambridge, England), 134 8, 1617-29

Chen, Lei; Liao, Guanghong; Yang, Linda; Campbell, Kenneth; Nakafuku, Masato; Kuan, Chia-Yi; Zheng, Yi 2006. Cdc42 deficiency causes Sonic hedgehog-independent holoprosencephaly. Proceedings of the National Academy of Sciences of the United States of America, 103 44, 16520-5

Ohori, Yasuo; Yamamoto, Shin-ichi; Nagao, Motoshi; Sugimori, Michiya; Yamamoto, Naoya; Nakamura, Kozo; Nakafuku, Masato 2006. Growth factor treatment and genetic manipulation stimulate neurogenesis and oligodendrogenesis by endogenous neural progenitors in the injured adult spinal cord. The Journal of neuroscience : the official journal of the Society for Neuroscience, 26 46, 11948-60

Patten, Brooke A; Sardi, S Pablo; Koirala, Samir; Nakafuku, Masato; Corfas, Gabriel 2006. Notch1 signaling regulates radial glia differentiation through multiple transcriptional mechanisms. The Journal of neuroscience : the official journal of the Society for Neuroscience, 26 12, 3102-8

Azuma, Noriyuki; Tadokoro, Keiko; Asaka, Astuko; Yamada, Masao; Yamaguchi, Yuki; Handa, Hiroshi; Matsushima, Satsuki; Watanabe, Takashi; Kida, Yasuyuki; Ogura, Toshihiko; Torii, Masaaki; Shimamura, Kenji; Nakafuku, Masato 2005. Transdifferentiation of the retinal pigment epithelia to the neural retina by transfer of the Pax6 transcriptional factor. Human molecular genetics, 14 8, 1059-68

Azuma, Noriyuki; Tadokoro, Keiko; Asaka, Astuko; Yamada, Masao; Yamaguchi, Yuki; Handa, Hiroshi; Matsushima, Satsuki; Watanabe, Takashi; Kohsaka, Shinichi; Kida, Yasuyuki; Shiraishi, Tomoki; Ogura, Toshihiko; Shimamura, Kenji; Nakafuku, Masato 2005. The Pax6 isoform bearing an alternative spliced exon promotes the development of the neural retinal structure. Human molecular genetics, 14 6, 735-45

Kriks, Sonja; Lanuza, Guillermo M; Mizuguchi, Rumiko; Nakafuku, Masato; Goulding, Martyn 2005. Gsh2 is required for the repression of Ngn1 and specification of dorsal interneuron fate in the spinal cord. Development (Cambridge, England), 132 13, 2991-3002

Kamakura, Sachiko; Oishi, Koji; Yoshimatsu, Takeshi; Nakafuku, Masato; Masuyama, Norihisa; Gotoh, Yukiko 2004. Hes binding to STAT3 mediates crosstalk between Notch and JAK-STAT signalling. Nature cell biology, 6 6, 547-54

Oishi, Koji; Kamakura, Sachiko; Isazawa, Yuko; Yoshimatsu, Takeshi; Kuida, Keisuke; Nakafuku, Masato; Masuyama, Norihisa; Gotoh, Yukiko 2004. Notch promotes survival of neural precursor cells via mechanisms distinct from those regulating neurogenesis. Developmental biology, 276 1, 172-84

Parras, Carlos M; Galli, Rossella; Britz, Olivier; Soares, Sylvia; Galichet, Christophe; Battiste, James; Johnson, Jane E; Nakafuku, Masato; Vescovi, Angelo; Guillemot, François 2004. Mash1 specifies neurons and oligodendrocytes in the postnatal brain. The EMBO journal, 23 22, 4495-505

Hashimoto-Torii, Kazue; Motoyama, Jun; Hui, Chi-Chung; Kuroiwa, Atsushi; Nakafuku, Masato; Shimamura, Kenji 2003. Differential activities of Sonic hedgehog mediated by Gli transcription factors define distinct neuronal subtypes in the dorsal thalamus. Mechanisms of development, 120 10, 1097-111

Hu, Qi-Dong; Ang, Beng-Ti; Karsak, Meliha; Hu, Wei-Ping; Cui, Xiao-Ying; Duka, Tanya; Takeda, Yasuo; Chia, Wendy; Sankar, Natesan; Ng, Yee-Kong; Ling, Eng-Ang; Maciag, Thomas; Small, Deena; Trifonova, Radianna; Kopan, Raphael; Okano, Hideyuki; Nakafuku, Masato; Chiba, Shigeru; Hirai, Hisamaru; Aster, Jon C; Schachner, Melitta; Pallen, Catherine J; Watanabe, Kazutada; Xiao, Zhi-Cheng 2003. F3/contactin acts as a functional ligand for Notch during oligodendrocyte maturation. Cell, 115 2, 163-75

Fu, Hui; Qi, Yingchuan; Tan, Min; Cai, Jun; Takebayashi, Hirohide; Nakafuku, Masato; Richardson, William; Qiu, Mengsheng 2002. Dual origin of spinal oligodendrocyte progenitors and evidence for the cooperative role of Olig2 and Nkx2.2 in the control of oligodendrocyte differentiation. Development (Cambridge, England), 129 3, 681-93

Heins, Nico; Malatesta, Paolo; Cecconi, Francesco; Nakafuku, Masato; Tucker, Kerry Lee; Hack, Michael A; Chapouton, Prisca; Barde, Yves-Alain; Götz, Magdalena 2002. Glial cells generate neurons: the role of the transcription factor Pax6. Nature neuroscience, 5 4, 308-15

Kamitori, Kazuyo; Machide, Mitsuru; Tomita, Kazuhiko; Nakafuku, Masato; Kohsaka, Shinichi 2002. Cell-type-specific expression of protein tyrosine kinase-related receptor RYK in the central nervous system of the rat. Brain research. Molecular brain research, 104 2, 255-66

Kobayashi, Daisuke; Kobayashi, Makoto; Matsumoto, Ken; Ogura, Toshihiko; Nakafuku, Masato; Shimamura, Kenji 2002. Early subdivisions in the neural plate define distinct competence for inductive signals. Development (Cambridge, England), 129 1, 83-93

Nakatomi, Hirofumi; Kuriu, Toshihiko; Okabe, Shigeo; Yamamoto, Shin-ichi; Hatano, Osamu; Kawahara, Nobutaka; Tamura, Akira; Kirino, Takaaki; Nakafuku, Masato 2002. Regeneration of hippocampal pyramidal neurons after ischemic brain injury by recruitment of endogenous neural progenitors. Cell, 110 4, 429-41