Erich W. Gulbins, MD, PhD

Becker, Katrin Anne; Fahsel, Björn; Kemper, Hannes; Mayeres, Joelina; Li, Cao; Wilker, Barbara; Keitsch, Simone; Soddemann, Matthias; Sehl, Carolin; Kohnen, Marcus; Edwards, Michael J; Grassmé, Heike; Caldwell, Charles C; Seitz, Aaron; Fraunholz, Martin; Gulbins, Erich 2018. Staphylococcus aureus Alpha-Toxin Disrupts Endothelial-Cell Tight Junctions via Acid Sphingomyelinase and Ceramide. Infection and immunity, 86 1,

Becker, Katrin Anne; Riethmüller, Joachim; Seitz, Aaron P; Gardner, Aaron; Boudreau, Ryan; Kamler, Markus; Kleuser, Burkhard; Schuchman, Edward; Caldwell, Charles C; Edwards, Michael J; Grassmé, Heike; Brodlie, Malcolm; Gulbins, Erich 2018. Sphingolipids as targets for inhalation treatment of cystic fibrosis. Advanced drug delivery reviews, ,

Kalinichenko, Liubov S; Gulbins, Erich; Kornhuber, Johannes; Müller, Christian P 2018. The role of sphingolipids in psychoactive drug use and addiction. Journal of neural transmission (Vienna, Austria : 1996), 125 4, 651-672

Keitsch, Simone; Riethmüller, Joachim; Soddemann, Matthias; Sehl, Carolin; Wilker, Barbara; Edwards, Michael J; Caldwell, Charles C; Fraunholz, Martin; Gulbins, Erich; Becker, Katrin Anne 2018. Pulmonary infection of cystic fibrosis mice with Staphylococcus aureus requires expression of ?-toxin. Biological chemistry, ,

Kim, Young; Abplanalp, William A; Jung, Andrew D; Schuster, Rebecca M; Lentsch, Alex B; Gulbins, Erich; Caldwell, Charles C; Pritts, Timothy A 2018. Endocytosis of Red Blood Cell Microparticles by Pulmonary Endothelial Cells is Mediated By Rab5. Shock (Augusta, Ga.), 49 3, 288-294

Li, Pin-Lan; Gulbins, Erich 2018. Bioactive Lipids and Redox Signaling: Molecular Mechanism and Disease Pathogenesis. Antioxidants & redox signaling, ,

Xia, Brent T; Beckmann, Nadine; Winer, Leah K; Kim, Young; Goetzman, Holly S; Veile, Rosalie E; Gulbins, Erich; Goodman, Michael D; Nomellini, Vanessa; Caldwell, Charles C 2018. Amitriptyline Treatment Mitigates Sepsis-Induced Tumor Necrosis Factor Expression and Coagulopathy. Shock (Augusta, Ga.), ,

Bao, Junxiang; Li, Guangbi; Yuan, Xinxu; Li, Pin-Lan; Gulbins, Erich 2017. Contribution of p62 to Phenotype Transition of Coronary Arterial Myocytes with Defective Autophagy. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 41 2, 555-568

Bao, Jun-Xiang; Zhang, Qin-Fang; Wang, Mi; Xia, Min; Boini, Krishna M; Gulbins, Erich; Zhang, Yang; Li, Pin-Lan 2017. Implication of CD38 gene in autophagic degradation of collagen I in mouse coronary arterial myocytes. Frontiers in bioscience (Landmark edition), 22 , 558-569

Becker, Katrin Anne; Beckmann, Nadine; Adams, Constantin; Hessler, Gabriele; Kramer, Melanie; Gulbins, Erich; Carpinteiro, Alexander 2017. Melanoma cell metastasis via P-selectin-mediated activation of acid sphingomyelinase in platelets. Clinical & experimental metastasis, 34 1, 25-35

Becker, Katrin Anne; Halmer, Ramona; Davies, Laura; Henry, Brian D; Ziobro-Henry, Regan; Decker, Yann; Liu, Yang; Gulbins, Erich; Fassbender, Klaus; Walter, Silke 2017. Blockade of Experimental Multiple Sclerosis by Inhibition of the Acid Sphingomyelinase/Ceramide System. Neuro-Signals, 25 1, 88-97

Becker, Katrin Anne; Li, Xiang; Seitz, Aaron; Steinmann, Joerg; Koch, Anne; Schuchman, Edward; Kamler, Markus; Edwards, Michael J; Caldwell, Charles C; Gulbins, Erich 2017. Neutrophils Kill Reactive Oxygen Species-Resistant Pseudomonas aeruginosa by Sphingosine. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 43 4, 1603-1616

Beckmann, Nadine; Becker, Katrin Anne; Walter, Silke; Becker, Jan U; Kramer, Melanie; Hessler, Gabriele; Weber, Stefanie; Göthert, Joachim R; Fassbender, Klaus; Gulbins, Erich; Carpinteiro, Alexander 2017. Regulation of Arthritis Severity by the Acid Sphingomyelinase. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 43 4, 1460-1471

Chami, Marwan; Halmer, Ramona; Schnoeder, Laura; Anne Becker, Katrin; Meier, Carola; Fassbender, Klaus; Gulbins, Erich; Walter, Silke 2017. Acid sphingomyelinase deficiency enhances myelin repair after acute and chronic demyelination. PloS one, 12 6, e0178622

Fayyaz, Susann; Japtok, Lukasz; Schumacher, Fabian; Wigger, Dominik; Schulz, Tim Julius; Haubold, Kathrin; Gulbins, Erich; Völler, Heinz; Kleuser, Burkhard 2017. Lysophosphatidic Acid Inhibits Insulin Signaling in Primary Rat Hepatocytes via the LPA3 Receptor Subtype and is Increased in Obesity. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 43 2, 445-456

Folkesson, Maggie; Vorkapic, Emina; Gulbins, Erich; Japtok, Lukasz; Kleuser, Burkhard; Welander, Martin; Länne, Toste; Wågsäter, Dick 2017. Inflammatory cells, ceramides, and expression of proteases in perivascular adipose tissue adjacent to human abdominal aortic aneurysms. Journal of vascular surgery, 65 4, 1171-1179.e1

Grassmé, Heike; Henry, Brian; Ziobro, Regan; Becker, Katrin Anne; Riethmüller, Joachim; Gardner, Aaron; Seitz, Aaron P; Steinmann, Joerg; Lang, Stephan; Ward, Christopher; Schuchman, Edward H; Caldwell, Charles C; Kamler, Markus; Edwards, Michael J; Brodlie, Malcolm; Gulbins, Erich 2017. ?1-Integrin Accumulates in Cystic Fibrosis Luminal Airway Epithelial Membranes and Decreases Sphingosine, Promoting Bacterial Infections. Cell host & microbe, 21 6, 707-718.e8

Hoehn, Richard S; Jernigan, Peter L; Japtok, Lukasz; Chang, Alex L; Midura, Emily F; Caldwell, Charles C; Kleuser, Burkhard; Lentsch, Alex B; Edwards, Michael J; Gulbins, Erich; Pritts, Timothy A 2017. Acid Sphingomyelinase Inhibition in Stored Erythrocytes Reduces Transfusion-Associated Lung Inflammation. Annals of surgery, 265 1, 218-226

Item, Flurin; Wueest, Stephan; Lemos, Vera; Stein, Sokrates; Lucchini, Fabrizio C; Denzler, Rémy; Fisser, Muriel C; Challa, Tenagne D; Pirinen, Eija; Kim, Youngsoo; Hemmi, Silvio; Gulbins, Erich; Gross, Atan; O'Reilly, Lorraine A; Stoffel, Markus; Auwerx, Johan; Konrad, Daniel 2017. Fas cell surface death receptor controls hepatic lipid metabolism by regulating mitochondrial function. Nature communications, 8 1, 480

Kovacic, Barbara; Sehl, Carolin; Wilker, Barbara; Kamler, Markus; Gulbins, Erich; Becker, Katrin Anne 2017. Glucosylceramide Critically Contributes to the Host Defense of Cystic Fibrosis Lungs. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 41 3, 1208-1218

Leanza, Luigi; Romio, Matteo; Becker, Katrin Anne; Azzolini, Michele; Trentin, Livio; Managò, Antonella; Venturini, Elisa; Zaccagnino, Angela; Mattarei, Andrea; Carraretto, Luca; Urbani, Andrea; Kadow, Stephanie; Biasutto, Lucia; Martini, Veronica; Severin, Filippo; Peruzzo, Roberta; Trimarco, Valentina; Egberts, Jan-Hendrik; Hauser, Charlotte; Visentin, Andrea; Semenzato, Gianpietro; Kalthoff, Holger; Zoratti, Mario; Gulbins, Erich; Paradisi, Cristina; Szabo, Ildiko 2017. Direct Pharmacological Targeting of a Mitochondrial Ion Channel Selectively Kills Tumor Cells In Vivo. Cancer cell, 31 4, 516-531.e10

Li, Cao; Wu, Yuqing; Riehle, Andrea; Ma, Jie; Kamler, Markus; Gulbins, Erich; Grassmé, Heike 2017. Staphylococcus aureus Survives in Cystic Fibrosis Macrophages, Forming a Reservoir for Chronic Pneumonia. Infection and immunity, 85 5,

Li, Cao; Wu, Yuqing; Riehle, Andrea; Orian-Rousseau, Véronique; Zhang, Yang; Gulbins, Erich; Grassmé, Heike 2017. Regulation of Staphylococcus aureus Infection of Macrophages by CD44, Reactive Oxygen Species, and Acid Sphingomyelinase. Antioxidants & redox signaling, ,

Ma, Jie; Gulbins, Erich; Edwards, Michael J; Caldwell, Charles C; Fraunholz, Martin; Becker, Katrin Anne 2017. Staphylococcus aureus ?-Toxin Induces Inflammatory Cytokines via Lysosomal Acid Sphingomyelinase and Ceramides. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 43 6, 2170-2184

Martin, Grace E; Boudreau, Ryan M; Couch, Caroline; Becker, Katrin Anne; Edwards, Michael J; Caldwell, Charles C; Gulbins, Erich; Seitz, Aaron 2017. Sphingosine's role in epithelial host defense: A natural antimicrobial and novel therapeutic. Biochimie, 141 , 91-96

Müller, Christian P; Kalinichenko, Liubov S; Tiesel, Jens; Witt, Matthias; Stöckl, Thomas; Sprenger, Eva; Fuchser, Jens; Beckmann, Janine; Praetner, Marc; Huber, Sabine E; Amato, Davide; Mühle, Christiane; Büttner, Christian; Ekici, Arif B; Smaga, Irena; Pomierny-Chamiolo, Lucyna; Pomierny, Bartosz; Filip, Malgorzata; Eulenburg, Volker; Gulbins, Erich; Lourdusamy, Anbarasu; Reichel, Martin; Kornhuber, Johannes 2017. Paradoxical antidepressant effects of alcohol are related to acid sphingomyelinase and its control of sphingolipid homeostasis. Acta neuropathologica, 133 3, 463-483

Rhein, Cosima; Reichel, Martin; Kramer, Marcel; Rotter, Andrea; Lenz, Bernd; Mühle, Christiane; Gulbins, Erich; Kornhuber, Johannes 2017. Alternative splicing of SMPD1 coding for acid sphingomyelinase in major depression. Journal of affective disorders, 209 , 10-15

Rice, Teresa C; Armocida, Stephanie M; Kuethe, Joshua W; Midura, Emily F; Jain, Ayushi; Hildeman, David A; Healy, Daniel P; Gulbins, Erich; Caldwell, Charles C 2017. Burn injury influences the T cell homeostasis in a butyrate-acid sphingomyelinase dependent manner. Cellular immunology, 313 , 25-31

Rice, Teresa C; Pugh, Amanda M; Seitz, Aaron P; Gulbins, Erich; Nomellini, Vanessa; Caldwell, Charles C 2017. Sphingosine rescues aged mice from pulmonary pseudomonas infection. The Journal of surgical research, 219 , 354-359

Rice, Teresa C; Pugh, Amanda M; Xia, Brent T; Seitz, Aaron P; Whitacre, Brynne E; Gulbins, Erich; Caldwell, Charles C 2017. Bronchoalveolar Lavage Microvesicles Protect Burn-Injured Mice from Pulmonary Infection. Journal of the American College of Surgeons, 225 4, 538-547

Schneider, Miriam; Levant, Beth; Reichel, Martin; Gulbins, Erich; Kornhuber, Johannes; Müller, Christian P 2017. Lipids in psychiatric disorders and preventive medicine. Neuroscience and biobehavioral reviews, 76 Pt B, 336-362

Schumacher, Fabian; Neuber, Corinna; Finke, Hannah; Nieschalke, Kai; Baesler, Jessica; Gulbins, Erich; Kleuser, Burkhard 2017. The sphingosine 1-phosphate breakdown product, (2E)-hexadecenal, forms protein adducts and glutathione conjugates in vitro. Journal of lipid research, 58 8, 1648-1660

Sydor, Svenja; Sowa, Jan-Peter; Megger, Dominik A; Schlattjan, Martin; Jafoui, Sami; Wingerter, Lena; Carpinteiro, Alexander; Baba, Hideo A; Bechmann, Lars P; Sitek, Barbara; Gerken, Guido; Gulbins, Erich; Canbay, Ali 2017. Acid sphingomyelinase deficiency in Western diet-fed mice protects against adipocyte hypertrophy and diet-induced liver steatosis. Molecular metabolism, 6 5, 416-427

Venturini, Elisa; Leanza, Luigi; Azzolini, Michele; Kadow, Stephanie; Mattarei, Andrea; Weller, Michael; Tabatabai, Ghazaleh; Edwards, Michael J; Zoratti, Mario; Paradisi, Cristina; Szabò, Ildikò; Gulbins, Erich; Becker, Katrin Anne 2017. Targeting the Potassium Channel Kv1.3 Kills Glioblastoma Cells. Neuro-Signals, 25 1, 26-38

Wu, Yuqing; Gulbins, Erich; Grassmé, Heike 2017. Crosstalk Between Sphingomyelinases and Reactive Oxygen Species in Mycobacterial Infection. Antioxidants & redox signaling, ,

Adams, Constantin; Icheva, Vanya; Deppisch, Caroline; Lauer, Josefine; Herrmann, Gloria; Graepler-Mainka, Ute; Heyder, Susanne; Gulbins, Erich; Riethmueller, Joachim 2016. Long-Term Pulmonal Therapy of Cystic Fibrosis-Patients with Amitriptyline. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 39 2, 565-72

Carpinteiro, Alexander; Beckmann, Nadine; Seitz, Aaron; Hessler, Gabriele; Wilker, Barbara; Soddemann, Matthias; Helfrich, Iris; Edelmann, Bärbel; Gulbins, Erich; Becker, Katrin Anne 2016. Role of Acid Sphingomyelinase-Induced Signaling in Melanoma Cells for Hematogenous Tumor Metastasis. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 38 1, 1-14

Gulbins, Anne; Grassmé, Heike; Hoehn, Richard; Kohnen, Marcus; Edwards, Michael J; Kornhuber, Johannes; Gulbins, Erich 2016. Role of Janus-Kinases in Major Depressive Disorder. Neuro-Signals, 24 1, 71-80

Gulbins, Anne; Grassmé, Heike; Hoehn, Richard; Wilker, Barbara; Soddemann, Matthias; Kohnen, Marcus; Edwards, Michael J; Kornhuber, Johannes; Gulbins, Erich 2016. Regulation of Neuronal Stem Cell Proliferation in the Hippocampus by Endothelial Ceramide. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 39 2, 790-801

Hoehn, Richard S; Jernigan, Peter L; Chang, Alex L; Edwards, Michael J; Caldwell, Charles C; Gulbins, Erich; Pritts, Timothy A 2016. Acid Sphingomyelinase Inhibition Prevents Hemolysis During Erythrocyte Storage. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 39 1, 331-40

Hoehn, Richard S; Seitz, Aaron P; Jernigan, Peter L; Gulbins, Erich; Edwards, Michael J 2016. Ischemia/Reperfusion Injury Alters Sphingolipid Metabolism in the Gut. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 39 4, 1262-70

Hoehn, Richard; Monse, Marlene; Pohl, Ella; Wranik, Sina; Wilker, Barbara; Keitsch, Simone; Soddemann, Matthias; Kornhuber, Johannes; Kohnen, Marcus; Edwards, Michael J; Grassmé, Heike; Gulbins, Erich 2016. Melatonin Acts as an Antidepressant by Inhibition of the Acid Sphingomyelinase/Ceramide System. Neuro-Signals, 24 1, 48-58

Hollmann, Claudia; Werner, Sandra; Avota, Elita; Reuter, Dajana; Japtok, Lukasz; Kleuser, Burkhard; Gulbins, Erich; Becker, Katrin Anne; Schneider-Schaulies, Jürgen; Beyersdorf, Niklas 2016. Inhibition of Acid Sphingomyelinase Allows for Selective Targeting of CD4+ Conventional versus Foxp3+ Regulatory T Cells. Journal of immunology (Baltimore, Md. : 1950), 197 8, 3130-3141

Huston, Joseph P; Kornhuber, Johannes; Mühle, Christiane; Japtok, Lukasz; Komorowski, Mara; Mattern, Claudia; Reichel, Martin; Gulbins, Erich; Kleuser, Burkhard; Topic, Bianca; De Souza Silva, Maria A; Müller, Christian P 2016. A sphingolipid mechanism for behavioral extinction. Journal of neurochemistry, 137 4, 589-603

Johnson, Bobby L; Rice, Teresa C; Xia, Brent T; Boone, Kirsten I; Green, Ellis A; Gulbins, Erich; Caldwell, Charles C 2016. Amitriptyline Usage Exacerbates the Immune Suppression Following Burn Injury. Shock (Augusta, Ga.), 46 5, 541-548

Leanza, Luigi; Managò, Antonella; Zoratti, Mario; Gulbins, Erich; Szabo, Ildiko 2016. Pharmacological targeting of ion channels for cancer therapy: In vivo evidences. Biochimica et biophysica acta, 1863 6 Pt B, 1385-97

Li, Cao; Peng, Huiming; Japtok, Lukasz; Seitz, Aaron; Riehle, Andrea; Wilker, Barbara; Soddemann, Matthias; Kleuser, Burkard; Edwards, Michael; Lammas, David; Zhang, Yang; Gulbins, Erich; Grassme, Heike 2016. Inhibition of neutral sphingomyelinase protects mice against systemic tuberculosis. Frontiers in bioscience (Elite edition), 8 , 311-25

Makdessi, Samar Al; Sweidan, Hicham; Schmid, Evi; Weimar, Udo; Gulbins, Erich; Lang, Florian 2016. Quantitative Determination of Ceramide Molecular Species in Dendritic Cells. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 39 4, 1608-17

Nojima, Hiroyuki; Freeman, Christopher M; Schuster, Rebecca M; Japtok, Lukasz; Kleuser, Burkhard; Edwards, Michael J; Gulbins, Erich; Lentsch, Alex B 2016. Hepatocyte exosomes mediate liver repair and regeneration via sphingosine-1-phosphate. Journal of hepatology, 64 1, 60-8

Nojima, Hiroyuki; Konishi, Takanori; Freeman, Christopher M; Schuster, Rebecca M; Japtok, Lukasz; Kleuser, Burkhard; Edwards, Michael J; Gulbins, Erich; Lentsch, Alex B 2016. Chemokine Receptors, CXCR1 and CXCR2, Differentially Regulate Exosome Release in Hepatocytes. PloS one, 11 8, e0161443

Rice, Teresa C; Seitz, Aaron P; Edwards, Michael J; Gulbins, Erich; Caldwell, Charles C 2016. Frontline Science: Sphingosine rescues burn-injured mice from pulmonary Pseudomonas aeruginosa infection. Journal of leukocyte biology, 100 6, 1233-1237

Tavakoli Tabazavareh, Shaghayegh; Seitz, Aaron; Jernigan, Peter; Sehl, Carolin; Keitsch, Simone; Lang, Stephan; Kahl, Barbara C; Edwards, Michael; Grassmé, Heike; Gulbins, Erich; Becker, Katrin Anne 2016. Lack of Sphingosine Causes Susceptibility to Pulmonary Staphylococcus Aureus Infections in Cystic Fibrosis. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 38 6, 2094-102

Wang, Lei; Chen, Yang; Li, Xiang; Zhang, Youzhi; Gulbins, Erich; Zhang, Yang 2016. Enhancement of endothelial permeability by free fatty acid through lysosomal cathepsin B-mediated Nlrp3 inflammasome activation. Oncotarget, 7 45, 73229-73241

Zhou, Yuetao; Salker, Madhuri S; Walker, Britta; Münzer, Patrick; Borst, Oliver; Gawaz, Meinrad; Gulbins, Erich; Singh, Yogesh; Lang, Florian 2016. Acid Sphingomyelinase (ASM) is a Negative Regulator of Regulatory T Cell (Treg) Development. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 39 3, 985-95

Zoicas, Iulia; Reichel, Martin; Gulbins, Erich; Kornhuber, Johannes 2016. Role of Acid Sphingomyelinase in the Regulation of Social Behavior and Memory. PloS one, 11 9, e0162498

Carpinteiro, Alexander; Becker, Katrin Anne; Japtok, Lukasz; Hessler, Gabriele; Keitsch, Simone; Požgajovà, Miroslava; Schmid, Kurt W; Adams, Constantin; Müller, Stefan; Kleuser, Burkhard; Edwards, Michael J; Grassmé, Heike; Helfrich, Iris; Gulbins, Erich 2015. Regulation of hematogenous tumor metastasis by acid sphingomyelinase. EMBO molecular medicine, 7 6, 714-34

Chen, Yang; Li, Xiang; Boini, Krishna M; Pitzer, Ashley L; Gulbins, Erich; Zhang, Yang; Li, Pin-Lan 2015. Endothelial Nlrp3 inflammasome activation associated with lysosomal destabilization during coronary arteritis. Biochimica et biophysica acta, 1853 2, 396-408

Grassmé, Heike; Jernigan, Peter L; Hoehn, Richard S; Wilker, Barbara; Soddemann, Matthias; Edwards, Michael J; Müller, Christian P; Kornhuber, Johannes; Gulbins, Erich 2015. Inhibition of Acid Sphingomyelinase by Antidepressants Counteracts Stress-Induced Activation of P38-Kinase in Major Depression. Neuro-Signals, 23 1, 84-92

Gulbins, Erich 2015. Highlight: molecular medicine of sphingolipids. Biological chemistry, 396 6-7, 569-71

Gulbins, Erich; Walter, Silke; Becker, Katrin Anne; Halmer, Ramona; Liu, Yang; Reichel, Martin; Edwards, Michael J; Müller, Christian P; Fassbender, Klaus; Kornhuber, Johannes 2015. A central role for the acid sphingomyelinase/ceramide system in neurogenesis and major depression. Journal of neurochemistry, 134 2, 183-92

Henry, Brian D; Neill, Daniel R; Becker, Katrin Anne; Gore, Suzanna; Bricio-Moreno, Laura; Ziobro, Regan; Edwards, Michael J; Mühlemann, Kathrin; Steinmann, Jörg; Kleuser, Burkhard; Japtok, Lukasz; Luginbühl, Miriam; Wolfmeier, Heidi; Scherag, André; Gulbins, Erich; Kadioglu, Aras; Draeger, Annette; Babiychuk, Eduard B 2015. Engineered liposomes sequester bacterial exotoxins and protect from severe invasive infections in mice. Nature biotechnology, 33 1, 81-8

Hilker, Rolf; Munder, Antje; Klockgether, Jens; Losada, Patricia Moran; Chouvarine, Philippe; Cramer, Nina; Davenport, Colin F; Dethlefsen, Sarah; Fischer, Sebastian; Peng, Huiming; Schönfelder, Torben; Türk, Oliver; Wiehlmann, Lutz; Wölbeling, Florian; Gulbins, Erich; Goesmann, Alexander; Tümmler, Burkhard 2015. Interclonal gradient of virulence in the Pseudomonas aeruginosa pangenome from disease and environment. Environmental microbiology, 17 1, 29-46

Jernigan, Peter L; Hoehn, Richard S; Grassmé, Heike; Edwards, Michael J; Müller, Christian P; Kornhuber, Johannes; Gulbins, Erich 2015. Sphingolipids in Major Depression. Neuro-Signals, 23 1, 49-58

Lang, Elisabeth; Bissinger, Rosi; Gulbins, Erich; Lang, Florian 2015. Ceramide in the regulation of eryptosis, the suicidal erythrocyte death. Apoptosis : an international journal on programmed cell death, 20 5, 758-67

Lang, Elisabeth; Gatidis, Sergios; Freise, Noemi F; Bock, Hans; Kubitz, Ralf; Lauermann, Christian; Orth, Hans Martin; Klindt, Caroline; Schuier, Maximilian; Keitel, Verena; Reich, Maria; Liu, Guilai; Schmidt, Sebastian; Xu, Haifeng C; Qadri, Syed M; Herebian, Diran; Pandyra, Aleksandra A; Mayatepek, Ertan; Gulbins, Erich; Lang, Florian; Häussinger, Dieter; Lang, Karl S; Föller, Michael; Lang, Philipp A 2015. Conjugated bilirubin triggers anemia by inducing erythrocyte death. Hepatology (Baltimore, Md.), 61 1, 275-84

Leanza, Luigi; Venturini, Elisa; Kadow, Stephanie; Carpinteiro, Alexander; Gulbins, Erich; Becker, Katrin Anne 2015. Targeting a mitochondrial potassium channel to fight cancer. Cell calcium, 58 1, 131-138

Lee, Hyunmi; Rotolo, Jimmy A; Mesicek, Judith; Penate-Medina, Tuula; Rimner, Andreas; Liao, Wen-Chieh; Yin, Xianglei; Ragupathi, Govind; Ehleiter, Desiree; Gulbins, Erich; Zhai, Dayong; Reed, John C; Haimovitz-Friedman, Adriana; Fuks, Zvi; Kolesnick, Richard 2015. Correction: Mitochondrial Ceramide-Rich Macrodomains Functionalize Bax upon Irradiation. PloS one, 10 12, e0146210

Managò, Antonella; Becker, Katrin Anne; Carpinteiro, Alexander; Wilker, Barbara; Soddemann, Matthias; Seitz, Aaron P; Edwards, Michael J; Grassmé, Heike; Szabò, Ildiko; Gulbins, Erich 2015. Pseudomonas aeruginosa pyocyanin induces neutrophil death via mitochondrial reactive oxygen species and mitochondrial acid sphingomyelinase. Antioxidants & redox signaling, 22 13, 1097-110

Merches, Katja; Khairnar, Vishal; Knuschke, Torben; Shaabani, Namir; Honke, Nadine; Duhan, Vikas; Recher, Mike; Navarini, Alexander A; Hardt, Cornelia; Häussinger, Dieter; Tümmler, Burkhard; Gulbins, Erich; Futerman, Anthony H; Hoffmann, Daniel; Lang, Florian; Lang, Philipp A; Westendorf, Astrid M; Lang, Karl S 2015. Virus-Induced Type I Interferon Deteriorates Control of Systemic Pseudomonas Aeruginosa Infection. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 36 6, 2379-92

Müller, Christian P; Reichel, Martin; Mühle, Christiane; Rhein, Cosima; Gulbins, Erich; Kornhuber, Johannes 2015. Brain membrane lipids in major depression and anxiety disorders. Biochimica et biophysica acta, 1851 8, 1052-1065

Nojima, Hiroyuki; Freeman, Christopher M; Gulbins, Erich; Lentsch, Alex B 2015. Sphingolipids in liver injury, repair and regeneration. Biological chemistry, 396 6-7, 633-43

Peng, Huiming; Li, Cao; Kadow, Stephanie; Henry, Brian D; Steinmann, Jörg; Becker, Katrin Anne; Riehle, Andrea; Beckmann, Natalie; Wilker, Barbara; Li, Pin-Lan; Pritts, Timothy; Edwards, Michael J; Zhang, Yang; Gulbins, Erich; Grassmé, Heike 2015. Acid sphingomyelinase inhibition protects mice from lung edema and lethal Staphylococcus aureus sepsis. Journal of molecular medicine (Berlin, Germany), 93 6, 675-89

Quillin, Ralph C; Wilson, Gregory C; Nojima, Hiroyuki; Freeman, Christopher M; Wang, Jiang; Schuster, Rebecca M; Blanchard, John A; Edwards, Michael J; Gandhi, Chandrashekhar R; Gulbins, Erich; Lentsch, Alex B 2015. Inhibition of acidic sphingomyelinase reduces established hepatic fibrosis in mice. Hepatology research : the official journal of the Japan Society of Hepatology, 45 3, 305-14

Reichel, Martin; Hönig, Stefanie; Liebisch, Gerhard; Lüth, Anja; Kleuser, Burkhard; Gulbins, Erich; Schmitz, Gerd; Kornhuber, Johannes 2015. Alterations of plasma glycerophospholipid and sphingolipid species in male alcohol-dependent patients. Biochimica et biophysica acta, 1851 11, 1501-10

Schumacher, Fabian; Chakraborty, Sudipta; Kleuser, Burkhard; Gulbins, Erich; Schwerdtle, Tanja; Aschner, Michael; Bornhorst, Julia 2015. Highly sensitive isotope-dilution liquid-chromatography-electrospray ionization-tandem-mass spectrometry approach to study the drug-mediated modulation of dopamine and serotonin levels in Caenorhabditis elegans. Talanta, 144 , 71-9

Seitz, Aaron P; Grassmé, Heike; Edwards, Michael J; Pewzner-Jung, Yael; Gulbins, Erich 2015. Ceramide and sphingosine in pulmonary infections. Biological chemistry, 396 6-7, 611-20

Beckmann, Nadine; Sharma, Deepa; Gulbins, Erich; Becker, Katrin Anne; Edelmann, Bärbel 2014. Inhibition of acid sphingomyelinase by tricyclic antidepressants and analogons. Frontiers in physiology, 5 , 331

Brown, Mary Beth; Hunt, William R; Noe, Julie E; Rush, Natalia I; Schweitzer, Kelly S; Leece, Thomas C; Moldobaeva, Aigul; Wagner, Elizabeth M; Dudek, Steven M; Poirier, Christophe; Presson, Robert G; Gulbins, Erich; Petrache, Irina 2014. Loss of cystic fibrosis transmembrane conductance regulator impairs lung endothelial cell barrier function and increases susceptibility to microvascular damage from cigarette smoke. Pulmonary circulation, 4 2, 260-8

Grassmé, Heike; Carpinteiro, Alexander; Edwards, Michael J; Gulbins, Erich; Becker, Katrin Anne 2014. Regulation of the inflammasome by ceramide in cystic fibrosis lungs. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 34 1, 45-55

Kornhuber, Johannes; Müller, Christian P; Becker, Katrin Anne; Reichel, Martin; Gulbins, Erich 2014. The ceramide system as a novel antidepressant target. Trends in pharmacological sciences, 35 6, 293-304

Li, Xiang; Zhang, Yang; Xia, Min; Gulbins, Erich; Boini, Krishna M; Li, Pin-Lan 2014. Activation of Nlrp3 inflammasomes enhances macrophage lipid-deposition and migration: implication of a novel role of inflammasome in atherogenesis. PloS one, 9 1, e87552

Mühle, Christiane; Amova, Violina; Biermann, Teresa; Bayerlein, Kristina; Richter-Schmidinger, Tanja; Kraus, Thomas; Reichel, Martin; Gulbins, Erich; Kornhuber, Johannes 2014. Sex-dependent decrease of sphingomyelinase activity during alcohol withdrawal treatment. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 34 1, 71-81

Münzer, Patrick; Borst, Oliver; Walker, Britta; Schmid, Evi; Feijge, Marion A H; Cosemans, Judith M E M; Chatterjee, Madhumita; Schmidt, Eva-Maria; Schmidt, Sebastian; Towhid, Syeda T; Leibrock, Christina; Elvers, Margitta; Schaller, Martin; Seizer, Peter; Ferlinz, Klaus; May, Andreas E; Gulbins, Erich; Heemskerk, Johan W M; Gawaz, Meinrad; Lang, Florian 2014. Acid sphingomyelinase regulates platelet cell membrane scrambling, secretion, and thrombus formation. Arteriosclerosis, thrombosis, and vascular biology, 34 1, 61-71

Neuber, Corinna; Schumacher, Fabian; Gulbins, Erich; Kleuser, Burkhard 2014. Method to simultaneously determine the sphingosine 1-phosphate breakdown product (2E)-hexadecenal and its fatty acid derivatives using isotope-dilution HPLC-electrospray ionization-quadrupole/time-of-flight mass spectrometry. Analytical chemistry, 86 18, 9065-73

Pewzner-Jung, Yael; Tavakoli Tabazavareh, Shaghayegh; Grassmé, Heike; Becker, Katrin Anne; Japtok, Lukasz; Steinmann, Jörg; Joseph, Tammar; Lang, Stephan; Tuemmler, Burkhard; Schuchman, Edward H; Lentsch, Alex B; Kleuser, Burkhard; Edwards, Michael J; Futerman, Anthony H; Gulbins, Erich 2014. Sphingoid long chain bases prevent lung infection by Pseudomonas aeruginosa. EMBO molecular medicine, 6 9, 1205-14

Reichel, Martin; Richter-Schmidinger, Tanja; Mühle, Christiane; Rhein, Cosima; Alexopoulos, Panagiotis; Schwab, Sibylle G; Gulbins, Erich; Kornhuber, Johannes 2014. The common acid sphingomyelinase polymorphism p.G508R is associated with self-reported allergy. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 34 1, 82-91

Siegmann, Nanna; Worbs, David; Effinger, Frauke; Bormann, Tobias; Gebhardt, Madlen; Ulrich, Martina; Wermeling, Fredrik; Müller-Hermelink, Eva; Biedermann, Tilo; Tighe, Mike; Edwards, Michael J; Caldwell, Charles; Leadbetter, Elizabeth; Karlsson, Mikael C I; Becker, Katrin Anne; Gulbins, Erich; Döring, Gerd 2014. Invariant natural killer T (iNKT) cells prevent autoimmunity, but induce pulmonary inflammation in cystic fibrosis. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 34 1, 56-70

Simonis, Alexander; Hebling, Sabrina; Gulbins, Erich; Schneider-Schaulies, Sibylle; Schubert-Unkmeir, Alexandra 2014. Differential activation of acid sphingomyelinase and ceramide release determines invasiveness of Neisseria meningitidis into brain endothelial cells. PLoS pathogens, 10 6, e1004160

Vidigal, Pedrina G; Müsken, Mathias; Becker, Katrin A; Häussler, Susanne; Wingender, Jost; Steinmann, Eike; Kehrmann, Jan; Gulbins, Erich; Buer, Jan; Rath, Peter Michael; Steinmann, Jörg 2014. Effects of green tea compound epigallocatechin-3-gallate against Stenotrophomonas maltophilia infection and biofilm. PloS one, 9 4, e92876

Zhang, Yang; Xu, Ming; Xia, Min; Li, Xiang; Boini, Krishna M; Wang, Mi; Gulbins, Erich; Ratz, Paul H; Li, Pin-Lan 2014. Defective autophagosome trafficking contributes to impaired autophagic flux in coronary arterial myocytes lacking CD38 gene. Cardiovascular research, 102 1, 68-78

Abed, Majed; Towhid, Syeda T; Pakladok, Tatsiana; Alesutan, Ioana; Götz, Friedrich; Gulbins, Erich; Lang, Florian 2013. Effect of bacterial peptidoglycan on erythrocyte death and adhesion to endothelial cells. International journal of medical microbiology : IJMM, 303 4, 182-9

Gramatzki, Dorothee; Herrmann, Caroline; Happold, Caroline; Becker, Katrin Anne; Gulbins, Erich; Weller, Michael; Tabatabai, Ghazaleh 2013. Glioma cell death induced by irradiation or alkylating agent chemotherapy is independent of the intrinsic ceramide pathway. PloS one, 8 5, e63527

Grassmé, Heike; Riethmüller, Joachim; Gulbins, Erich 2013. Ceramide in cystic fibrosis. Handbook of experimental pharmacology, 216, 265-74

Gulbins, Erich; Kolesnick, Richard N 2013. It takes a CAD to kill a tumor cell with a LMP. Cancer cell, 24 3, 279-81

Gulbins, Erich; Palmada, Monica; Reichel, Martin; Lüth, Anja; Böhmer, Christoph; Amato, Davide; Müller, Christian P; Tischbirek, Carsten H; Groemer, Teja W; Tabatabai, Ghazaleh; Becker, Katrin A; Tripal, Philipp; Staedtler, Sven; Ackermann, Teresa F; van Brederode, Johannes; Alzheimer, Christian; Weller, Michael; Lang, Undine E; Kleuser, Burkhard; Grassmé, Heike; Kornhuber, Johannes 2013. Acid sphingomyelinase-ceramide system mediates effects of antidepressant drugs. Nature medicine, 19 7, 934-8

Henry, Brian; Möller, Christina; Dimanche-Boitrel, Marie-Therese; Gulbins, Erich; Becker, Katrin Anne 2013. Targeting the ceramide system in cancer. Cancer letters, 332 2, 286-94

Henry, Brian; Ziobro, Regan; Becker, Katrin Anne; Kolesnick, Richard; Gulbins, Erich 2013. Acid sphingomyelinase. Handbook of experimental pharmacology, 215, 77-88

Kornhuber, Johannes; Tripal, Philipp; Gulbins, Erich; Muehlbacher, Markus 2013. Functional inhibitors of acid sphingomyelinase (FIASMAs). Handbook of experimental pharmacology, 215, 169-86

Leanza, Luigi; Biasutto, Lucia; Managò, Antonella; Gulbins, Erich; Zoratti, Mario; Szabò, Ildikò 2013. Intracellular ion channels and cancer. Frontiers in physiology, 4 , 227

Mühle, Christiane; Huttner, Hagen B; Walter, Silke; Reichel, Martin; Canneva, Fabio; Lewczuk, Piotr; Gulbins, Erich; Kornhuber, Johannes 2013. Characterization of acid sphingomyelinase activity in human cerebrospinal fluid. PloS one, 8 5, e62912

Nährlich, Lutz; Mainz, Jochen G; Adams, Constantin; Engel, Corinna; Herrmann, Gloria; Icheva, Vanya; Lauer, Josefine; Deppisch, Caroline; Wirth, Andreas; Unger, Katy; Graepler-Mainka, Ute; Hector, Andreas; Heyder, Susanne; Stern, Martin; Döring, Gerd; Gulbins, Erich; Riethmüller, Joachim 2013. Therapy of CF-patients with amitriptyline and placebo--a randomised, double-blind, placebo-controlled phase IIb multicenter, cohort-study. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 31 4-5, 505-12

Xu, Ming; Li, Xiao-Xue; Xiong, Jing; Xia, Min; Gulbins, Erich; Zhang, Yang; Li, Pin-Lan 2013. Regulation of autophagic flux by dynein-mediated autophagosomes trafficking in mouse coronary arterial myocytes. Biochimica et biophysica acta, 1833 12, 3228-36

Ziobro, Regan; Henry, Brian; Edwards, Michael J; Lentsch, Alex B; Gulbins, Erich 2013. Ceramide mediates lung fibrosis in cystic fibrosis. Biochemical and biophysical research communications, 434 4, 705-9

Abed, Majed; Towhid, Syeda T; Mia, Sobuj; Pakladok, Tatsiana; Alesutan, Ioana; Borst, Oliver; Gawaz, Meinrad; Gulbins, Erich; Lang, Florian 2012. Sphingomyelinase-induced adhesion of eryptotic erythrocytes to endothelial cells. American journal of physiology. Cell physiology, 303 9, C991-9

Becker, Katrin Anne; Henry, Brian; Ziobro, Regan; Tümmler, Burkhard; Gulbins, Erich; Grassmé, Heike 2012. Role of CD95 in pulmonary inflammation and infection in cystic fibrosis. Journal of molecular medicine (Berlin, Germany), 90 9, 1011-23

Leanza, Luigi; Henry, Brian; Sassi, Nicola; Zoratti, Mario; Chandy, K George; Gulbins, Erich; Szabò, Ildikò 2012. Inhibitors of mitochondrial Kv1.3 channels induce Bax/Bak-independent death of cancer cells. EMBO molecular medicine, 4 7, 577-93

Li, Xiang; Gulbins, Erich; Zhang, Yang 2012. Role of kinase suppressor of ras-1 in lipopolysaccharide-induced acute lung injury. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 30 4, 905-14

Li, Xiang; Gulbins, Erich; Zhang, Yang 2012. Oxidative stress triggers Ca-dependent lysosome trafficking and activation of acid sphingomyelinase. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 30 4, 815-26

Rhein, Cosima; Tripal, Philipp; Seebahn, Angela; Konrad, Alice; Kramer, Marcel; Nagel, Christine; Kemper, Jonas; Bode, Jens; Mühle, Christiane; Gulbins, Erich; Reichel, Martin; Becker, Cord-Michael; Kornhuber, Johannes 2012. Functional implications of novel human acid sphingomyelinase splice variants. PloS one, 7 4, e35467

Szabò, Ildikò; Leanza, Luigi; Gulbins, Erich; Zoratti, Mario 2012. Physiology of potassium channels in the inner membrane of mitochondria. Pflügers Archiv : European journal of physiology, 463 2, 231-46

Avota, Elita; Gulbins, Erich; Schneider-Schaulies, Sibylle 2011. DC-SIGN mediated sphingomyelinase-activation and ceramide generation is essential for enhancement of viral uptake in dendritic cells. PLoS pathogens, 7 2, e1001290

Becker, Katrin Anne; Henry, Brian; Ziobro, Regan; Riethmüller, Joachim; Gulbins, Erich 2011. Lipids in cystic fibrosis. Expert review of respiratory medicine, 5 4, 527-35

Cheng, Yu; Gulbins, Erich; Siemen, Detlef 2011. Activation of the permeability transition pore by Bax via inhibition of the mitochondrial BK channel. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 27 3-4, 191-200

Dimanche-Boitrel, Marie-Thérèse; Rebillard, Amélie; Gulbins, Erich 2011. Ceramide in chemotherapy of tumors. Recent patents on anti-cancer drug discovery, 6 3, 284-93

Kornhuber, Johannes; Muehlbacher, Markus; Trapp, Stefan; Pechmann, Stefanie; Friedl, Astrid; Reichel, Martin; Mühle, Christiane; Terfloth, Lothar; Groemer, Teja W; Spitzer, Gudrun M; Liedl, Klaus R; Gulbins, Erich; Tripal, Philipp 2011. Identification of novel functional inhibitors of acid sphingomyelinase. PloS one, 6 8, e23852

Lang, Florian; Ullrich, Susanne; Gulbins, Erich 2011. Ceramide formation as a target in beta-cell survival and function. Expert opinion on therapeutic targets, 15 9, 1061-71

Lee, Hyunmi; Rotolo, Jimmy A; Mesicek, Judith; Penate-Medina, Tuula; Rimner, Andreas; Liao, Wen-Chieh; Yin, Xianglei; Ragupathi, Govind; Ehleiter, Desiree; Gulbins, Erich; Zhai, Dayong; Reed, John C; Haimovitz-Friedman, Adriana; Fuks, Zvi; Kolesnick, Richard 2011. Mitochondrial ceramide-rich macrodomains functionalize Bax upon irradiation. PloS one, 6 6, e19783

Meyer zu Hörste, Melissa; Ströher, Elena; Berchner-Pfannschmidt, Utta; Schmitz-Spanke, Simone; Pink, Mario; Göthert, Joachim R; Fischer, Jens W; Gulbins, Erich; Eckstein, Anja K 2011. A novel mechanism involved in the pathogenesis of Graves ophthalmopathy (GO): clathrin is a possible targeting molecule for inhibiting local immune response in the orbit. The Journal of clinical endocrinology and metabolism, 96 11, E1727-36

Munder, Antje; Wölbeling, Florian; Kerber-Momot, Tanja; Wedekind, Dirk; Baumann, Ulrich; Gulbins, Erich; Tümmler, Burkhard 2011. Acute intratracheal Pseudomonas aeruginosa infection in cystic fibrosis mice is age-independent. Respiratory research, 12 , 148

Reichel, Martin; Beck, Johannes; Mühle, Christiane; Rotter, Andrea; Bleich, Stefan; Gulbins, Erich; Kornhuber, Johannes 2011. Activity of secretory sphingomyelinase is increased in plasma of alcohol-dependent patients. Alcoholism, clinical and experimental research, 35 10, 1852-9

Zhang, Yang; Li, Xiang; Carpinteiro, Alexander; Goettel, Jeremy A; Soddemann, Matthias; Gulbins, Erich 2011. Kinase suppressor of Ras-1 protects against pulmonary Pseudomonas aeruginosa infections. Nature medicine, 17 3, 341-6

Becker, Katrin Anne; Grassmé, Heike; Zhang, Yang; Gulbins, Erich 2010. Ceramide in Pseudomonas aeruginosa infections and cystic fibrosis. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 26 1, 57-66

Becker, Katrin Anne; Riethmüller, Joachim; Lüth, Anja; Döring, Gerd; Kleuser, Burkhard; Gulbins, Erich 2010. Acid sphingomyelinase inhibitors normalize pulmonary ceramide and inflammation in cystic fibrosis. American journal of respiratory cell and molecular biology, 42 6, 716-24

Becker, Katrin Anne; Riethmüller, Joachim; Zhang, Yang; Gulbins, Erich 2010. The role of sphingolipids and ceramide in pulmonary inflammation in cystic fibrosis. The open respiratory medicine journal, 4 , 39-47

Becker, Katrin Anne; Tümmler, Burkhard; Gulbins, Erich; Grassmé, Heike 2010. Accumulation of ceramide in the trachea and intestine of cystic fibrosis mice causes inflammation and cell death. Biochemical and biophysical research communications, 403 3-4, 368-74

Grassmé, Heike; Becker, Katrin Anne; Zhang, Yang; Gulbins, Erich 2010. CFTR-dependent susceptibility of the cystic fibrosis-host to Pseudomonas aeruginosa. International journal of medical microbiology : IJMM, 300 8, 578-83

Gulbins, Erich 2010. Lipids control mucus production in cystic fibrosis. Nature medicine, 16 3, 267-8

Kornhuber, Johannes; Tripal, Philipp; Reichel, Martin; Mühle, Christiane; Rhein, Cosima; Muehlbacher, Markus; Groemer, Teja W; Gulbins, Erich 2010. Functional Inhibitors of Acid Sphingomyelinase (FIASMAs): a novel pharmacological group of drugs with broad clinical applications. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 26 1, 9-20

Lang, Elisabeth; Lang, Philipp A; Shumilina, Ekaterina; Qadri, Syed M; Kucherenko, Yuliya; Kempe, Daniela S; Föller, Michael; Capasso, Anna; Wieder, Thomas; Gulbins, Erich; Clemen, Christoph S; Herr, Claudia; Noegel, Angelika A; Huber, Stephan M; Lang, Florian 2010. Enhanced eryptosis of erythrocytes from gene-targeted mice lacking annexin A7. Pflügers Archiv : European journal of physiology, 460 3, 667-76

Lang, Florian; Gulbins, Erich; Lang, Philipp A; Zappulla, Donatella; Föller, Michael 2010. Ceramide in suicidal death of erythrocytes. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 26 1, 21-8

Perrotta, Cristiana; Bizzozero, Laura; Cazzato, Denise; Morlacchi, Sara; Assi, Emma; Simbari, Fabio; Zhang, Yang; Gulbins, Erich; Bassi, Maria Teresa; Rosa, Patrizia; Clementi, Emilio 2010. Syntaxin 4 is required for acid sphingomyelinase activity and apoptotic function. The Journal of biological chemistry, 285 51, 40240-51

Reichel, Martin; Greiner, Elisabeth; Richter-Schmidinger, Tanja; Yedibela, Ozlem; Tripal, Philipp; Jacobi, Andrea; Bleich, Stefan; Gulbins, Erich; Kornhuber, Johannes 2010. Increased acid sphingomyelinase activity in peripheral blood cells of acutely intoxicated patients with alcohol dependence. Alcoholism, clinical and experimental research, 34 1, 46-50

Szabò, Ildikò; Zoratti, Mario; Gulbins, Erich 2010. Contribution of voltage-gated potassium channels to the regulation of apoptosis. FEBS letters, 584 10, 2049-56

Ulrich, Martina; Worlitzsch, Dieter; Viglio, Simona; Siegmann, Nanna; Iadarola, Paolo; Shute, Janis K; Geiser, Marianne; Pier, Gerald B; Friedel, Godehard; Barr, Mark L; Schuster, Antje; Meyer, Keith C; Ratjen, Felix; Bjarnsholt, Thomas; Gulbins, Erich; Döring, Gerd 2010. Alveolar inflammation in cystic fibrosis. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 9 3, 217-27

Verdurmen, Wouter P R; Thanos, Melissa; Ruttekolk, Ivo R; Gulbins, Erich; Brock, Roland 2010. Cationic cell-penetrating peptides induce ceramide formation via acid sphingomyelinase: implications for uptake. Journal of controlled release : official journal of the Controlled Release Society, 147 2, 171-9

Xuan, Nguyen Thi; Shumilina, Ekaterina; Gulbins, Erich; Gu, Shuchen; Götz, Friedrich; Lang, Florian 2010. Triggering of dendritic cell apoptosis by xanthohumol. Molecular nutrition & food research, 54 Suppl 2 , S214-24

Xuan, Nguyen Thi; Shumilina, Ekaterina; Kempe, Daniela S; Gulbins, Erich; Lang, Florian 2010. Sphingomyelinase dependent apoptosis of dendritic cells following treatment with amyloid peptides. Journal of neuroimmunology, 219 1-2, 81-9

Xuan, Nguyen Thi; Shumilina, Ekaterina; Schmid, Evi; Bhavsar, Shefalee K; Rexhepaj, Rexhep; Götz, Friedrich; Gulbins, Erich; Lang, Florian 2010. Role of acidic sphingomyelinase in thymol-mediated dendritic cell death. Molecular nutrition & food research, 54 12, 1833-41

Zhang, Yang; Li, Xiang; Grassmé, Heike; Döring, Gerd; Gulbins, Erich 2010. Alterations in ceramide concentration and pH determine the release of reactive oxygen species by Cftr-deficient macrophages on infection. Journal of immunology (Baltimore, Md. : 1950), 184 9, 5104-11

Banner, Katharine H; De Jonge, Hugo; Elborn, Stuart; Growcott, Ellena; Gulbins, Erich; Konstan, Mike; Moss, Rick; Poll, Chris; Randell, Scott H; Rossi, Adriano G; Thomas, Lorraine; Waltz, David 2009. Highlights of a workshop to discuss targeting inflammation in cystic fibrosis. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 8 1, 1-8

Braun, Manuel; Föller, Michael; Gulbins, Erich; Lang, Florian 2009. Eryptosis triggered by bismuth. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 22 3, 453-60

Döring, Gerd; Gulbins, Erich 2009. Cystic fibrosis and innate immunity: how chloride channel mutations provoke lung disease. Cellular microbiology, 11 2, 208-16

Dumitru, Claudia A; Sandalcioglu, Ibrahim E; Wagner, Marek; Weller, Michael; Gulbins, Erich 2009. Lysosomal ceramide mediates gemcitabine-induced death of glioma cells. Journal of molecular medicine (Berlin, Germany), 87 11, 1123-32

Dumitru, Claudia Alexandra; Weller, Michael; Gulbins, Erich 2009. Ceramide metabolism determines glioma cell resistance to chemotherapy. Journal of cellular physiology, 221 3, 688-95

Föller, Michael; Bobbala, Diwakar; Koka, Saisudha; Huber, Stephan M; Gulbins, Erich; Lang, Florian 2009. Suicide for survival--death of infected erythrocytes as a host mechanism to survive malaria. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 24 3-4, 133-40

Gassert, Evelyn; Avota, Elita; Harms, Harry; Krohne, Georg; Gulbins, Erich; Schneider-Schaulies, Sibylle 2009. Induction of membrane ceramides: a novel strategy to interfere with T lymphocyte cytoskeletal reorganisation in viral immunosuppression. PLoS pathogens, 5 10, e1000623

Kornhuber, Johannes; Reichel, Martin; Tripal, Philipp; Groemer, Teja W; Henkel, Andreas W; Mühle, Christiane; Gulbins, Erich 2009. The role of ceramide in major depressive disorder. European archives of psychiatry and clinical neuroscience, 259 Suppl 2 , S199-204

Lang, Philipp A; Kasinathan, Ravi S; Brand, Verena B; Duranton, Christophe; Lang, Camelia; Koka, Saisudha; Shumilina, Ekaterina; Kempe, Daniela S; Tanneur, Valerie; Akel, Ahmad; Lang, Karl S; Foller, Michael; Kun, Jurgen F J; Kremsner, Peter G; Wesselborg, Sebastian; Laufer, Stefan; Clemen, Christoph S; Herr, Claudia; Noegel, Angelika A; Wieder, Thomas; Gulbins, Erich; Lang, Florian; Huber, Stephan M 2009. Accelerated clearance of Plasmodium-infected erythrocytes in sickle cell trait and annexin-A7 deficiency. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 24 5-6, 415-28

Riethmüller, Joachim; Anthonysamy, Janina; Serra, Emilio; Schwab, Matthias; Döring, Gerd; Gulbins, Erich 2009. Therapeutic efficacy and safety of amitriptyline in patients with cystic fibrosis. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 24 1-2, 65-72

Zhang, Yang; Li, Xiang; Becker, Katrin Anne; Gulbins, Erich 2009. Ceramide-enriched membrane domains--structure and function. Biochimica et biophysica acta, 1788 1, 178-83

Zoratti, Mario; De Marchi, Umberto; Gulbins, Erich; Szabò, Ildikò 2009. Novel channels of the inner mitochondrial membrane. Biochimica et biophysica acta, 1787 5, 351-63

Carpinteiro, Alexander; Dumitru, Claudia; Schenck, Marcus; Gulbins, Erich 2008. Ceramide-induced cell death in malignant cells. Cancer letters, 264 1, 1-10

Gulbins, Erich 2008. Highlight: sphingolipids - signals and disease. Biological chemistry, 389 11, 1347-8

Kornhuber, Johannes; Tripal, Philipp; Reichel, Martin; Terfloth, Lothar; Bleich, Stefan; Wiltfang, Jens; Gulbins, Erich 2008. Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model. Journal of medicinal chemistry, 51 2, 219-37

Lang, Florian; Gulbins, Erich; Lerche, Holger; Huber, Stephan M; Kempe, Daniela S; Foller, Michael 2008. Eryptosis, a window to systemic disease. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 22 5-6, 373-80

Möröy, Tarik; Zeng, Hui; Jin, Jianmin; Schmid, Kurt Werner; Carpinteiro, Alexander; Gulbins, Erich 2008. The zinc finger protein and transcriptional repressor Gfi1 as a regulator of the innate immune response. Immunobiology, 213 3-4, 341-52

Gulbins E.;Schlottmann K.;Brenner B.;Lang F.;Coggeshall K. 12-26-1995. Molecular Analysis of Ras Activation by Tyrosine Phosphorylated Vav Biochemical and Biophysical Research Communications, 217 3, 876-885

Brenner B.;Gulbins E.;Schlottmann K.;Koppenhoefer U.;Busch G.;Walzog B.;Steinhausen M.;Coggeshall K.;Linderkamp O.;Lang F. 12-24-1996. L-Selectin activates the Ras pathway via the tyrosine kinase p56^lck Proceedings of the National Academy of Sciences of the United States of America, 93 26, 15376-15381

Walev I.;Tappe D.;Gulbins E.;Bhakdi S. 12-21-2000. Streptolysin O-permeabilized granulocytes shed L-selectin concomitantly with ceramide generation via Journal of Leukocyte Biology, 68 6, 865-872

Mühle C.;Weinland C.;Gulbins E.;Lenz B.;Kornhuber J. 12-13-2018. Peripheral acid sphingomyelinase activity is associated with biomarkers and phenotypes of alcohol us International Journal of Molecular Sciences, 19 12,

Gulbins E.;Jekle A.;Ferlinz K.;Grassmé H.;Lang F. 12-07-2000. Physiology of apoptosis American Journal of Physiology - Renal Physiology, 279 4 48-4,

Leanza L.;Zoratti M.;Gulbins E.;Szabo I. 12-04-2014. Mitochondrial ion channels as oncological targets Oncogene, 33 49, 5569-5581

Busch G.;Wiesinger H.;Gulbins E.;Wagner H.;Hamprecht B.;Lang F. 12-04-1996. Effect of astroglial cell swelling on pH of acidic intracellular compartments Biochimica et Biophysica Acta - Biomembranes, 1285 2, 212-218

Esen M.;Schreiner B.;Jendrossek V.;Lang F.;Fassbender K.;Grassmé H.;Gulbins E. 12-03-2001. Mechanisms of Staphylococcus aureus induced apoptosis of human endothelial cells Apoptosis, 6 6, 431-439

Beckmann N.;Becker K.A.;Kadow S.;Schumacher F.;Kramer M.;Kühn C.;Schulz-Schaeffer W.J.;Edwards M.J.;Kleuser B.;Gulbins E.;Carpinteiro A. 12-02-2019. Acid sphingomyelinase deficiency ameliorates farber disease International Journal of Molecular Sciences, 20 24,

Bhat O.M.;Li G.;Yuan X.;Huang D.;Gulbins E.;Kukreja R.C.;Li P.L. 12-01-2020. Arterial Medial Calcification through Enhanced small Extracellular Vesicle Release in Smooth Muscle- Scientific Reports, 10 1,

Lang J.;Bohn P.;Bhat H.;Jastrow H.;Walkenfort B.;Cansiz F.;Fink J.;Bauer M.;Olszewski D.;Ramos-Nascimento A.;Duhan V.;Friedrich S.K.;Becker K.A.;Krawczyk A.;Edwards M.J.;Burchert A.;Huber M.;Friebus-Kardash J.;Göthert J.R.;Hardt C.;Probst H.C.;Schumacher F.;Köhrer K.;Kleuser B.;Babiychuk E.B.;Sodeik B.;Seibel J.;Greber U.F.;Lang P.A.;Gulbins E.;Lang K.S. 12-01-2020. Acid ceramidase of macrophages traps herpes simplex virus in multivesicular bodies and protects from Nature Communications, 11 1,

McElvaney O.J.;Zaslona Z.;Becker-Flegler K.;Palsson-McDermott E.M.;Boland F.;Gunaratnam C.;Gulbins E.;O'Neill L.A.;Reeves E.P.;McElvaney N.G. 12-01-2019. Specific inhibition of the NLRP3 inflammasome as an antiinflammatory strategy in cystic fibrosis American Journal of Respiratory and Critical Care Medicine, 200 11, 1381-1391

Morris M.;Kassam F.;Bercz A.;Beckmann N.;Schumacher F.;Gulbins E.;Makley A.;Goodman M. 12-01-2019. The Role of Chemoprophylactic Agents in Modulating Platelet Aggregability After Traumatic Brain Inju Journal of Surgical Research, 244 , 1-8

Gulbins A.;Schumacher F.;Becker K.;Wilker B.;Soddemann M.;Boldrin F.;Müller C.;Edwards M.;Goodman M.;Caldwell C.;Kleuser B.;Kornhuber J.;Szabo I.;Gulbins E. 12-01-2018. Antidepressants regulate autophagy by targeting acid sphingomyelinase Molecular Psychiatry, 23 12, 2251

Gulbins A.;Schumacher F.;Becker K.;Wilker B.;Soddemann M.;Boldrin F.;Müller C.;Edwards M.;Goodman M.;Caldwell C.;Kleuser B.;Kornhuber J.;Szabo I.;Gulbins E. 12-01-2018. Antidepressants act by inducing autophagy controlled by sphingomyelin–ceramide Molecular Psychiatry, 23 12, 2324-2346

Rhein C.;Löber S.;Gmeiner P.;Gulbins E.;Tripal P.;Kornhuber J. 12-01-2018. Derivatization of common antidepressant drugs increases inhibition of acid sphingomyelinase and redu Journal of Neural Transmission, 125 12, 1837-1845

Wu Y.;Li C.;Riehle A.;Pollmeier B.;Gulbins E.;Grassmé H. 12-01-2018. Mycobacterial infection is promoted by neutral sphingomyelinase 2 regulating a signaling cascade lea Cellular Physiology and Biochemistry, 51 4, 1815-1829

Lee H.;Rotolo J.;Mesicek J.;Penate-Medina T.;Rimner A.;Liao W.;Yin X.;Ragupathi G.;Ehleiter D.;Gulbins E.;Zhai D.;Reed J.;Haimovitz-Friedman A.;Fuks Z.;Kolesnick R. 12-01-2015. Correction: Mitochondrial ceramide-rich macrodomains functionalize bax upon irradiation PLoS ONE, 10 12,

Gulbins E.;Petrache I. 12-01-2013. Preface Handbook of Experimental Pharmacology, 216 ,

Mühle C.;Reichel M.;Gulbins E.;Kornhuber J. 12-01-2013. Sphingolipids in psychiatric disorders and pain syndromes Handbook of Experimental Pharmacology, 216 , 431-456

Ziobro R.;Henry B.;Lentsch A.;Edwards M.;Riethmüller J.;Gulbins E. 12-01-2013. Ceramide in cystic fibrosis Clinical Lipidology, 8 6, 681-691

Imhäuser C.;Gulbins H.;Gulbins E.;Lipinski H. 12-01-2010. 3D visualization and colocalization of proteins and ceramide-rich domains CEUR Workshop Proceedings, 574 , 211-215

Imhäuser C.;Gulbins H.;Gulbins E.;Lipinski H. 12-01-2010. 3D topology and arrangement of proteins inside ceramide-rich domains Progress in Biomedical Optics and Imaging - Proceedings of SPIE, 7715 ,

Granseier M.;Grassmé H.;Gulbins E.;Lipinski H. 12-01-2009. Stereoscopic visualization of mammalian macrophages infected by pathogenic bacteria IFMBE Proceedings, 25 4, 437-440

Granseier M.;Grassmé H.;Gulbins E.;Lipinski H.G. 12-01-2009. Stereoscopic visualization of an infection of mammalian cells by pathogenic bacteria Informatik aktuell, , 366-370

Deigner H.;Gulbins E.;Claus R. 12-01-2007. Sphingolipid metabolism in systemic inflammation Intensive Care Medicine: Annual Update 2007, , 249-266

Lang F.;Lepple-Wienhues A.;Szabo I.;Gulbins E.;Palmada M.;Wallisch S.;Böhmer C.;Klingel K.;Kandolf R. 12-01-2005. Kinases, cell volume, and the regulation of chloride channels Advances in Experimental Medicine and Biology, 558 , 73-81

Lang F.;Wagner C.;Madlung J.;Uhlemann A.;Szabo I.;Lepple-Wienhues A.;Gulbins E.;Melzig J.;Völkl H.;Waldegger S.;Bröer S. 12-01-1999. Osmoregulatory amino acid transport, cell volume and control of cell function Amino Acids, 17 1, 47

Lang F.;Wienhues A.L.;Szabó I.;Siemen D.;Gulbins E. 12-01-1998. Cell volume in cell proliferation and apoptotic cell death Contributions to Nephrology, 123 , 158-168

Grassmé H.;Gulbins E.;Brenner B.;Ferlinz K.;Sandhoff K.;Harzer K.;Lang F.;Meyer T. 11-28-1997. Acidic sphingomyelinase mediates entry of N. gonorrhoeae into Nonphagocytic cells Cell, 91 5, 605-615

Busch G.;Völkl H.;Ritter M.;Gulbins E.;Häussinger D.;Lang F. 11-28-1996. Water, electrolyte and acid base disturbances in renal insufficiency. Physiological and pathophysiol Clinical Nephrology, 46 4, 270-273

Lepple-Wienhues A.;Belka C.;Laun T.;Jekle A.;Walter B.;Wieland U.;Welz M.;Heil L.;Kun J.;Busch G.;Weller M.;Bamberg M.;Gulbins E.;Lang F. 11-23-1999. Stimulation of CD95 (Fas) blocks T lymphocyte calcium channels through sphingomyelinase and sphingol Proceedings of the National Academy of Sciences of the United States of America, 96 24, 13795-13800

Brenner B.;Koppenhoefer U.;Grassmé H.;Kun J.;Lang F.;Gulbins E. 11-17-1997. Evidence for a novel function of the CD40 ligand as a significant molecule in T-lymphocyte FEBS Letters, 417 3, 301-306

Grassme H.;Kirschnek S.;Riethmueller J.;Riehle A.;Von Kurthy G.;Lang F.;Weller M.;Gulbins E. 11-13-2000. CD95/CD95 ligand interactions on epithelial cells in host defense to Pseudomonas aeruginosa Science, 290 5491, 527-530

Szabó I.;Bock J.;Grassmé H.;Soddemann M.;Wilker B.;Lang F.;Zoratti M.;Gulbins E. 11-11-2008. Mitochondrial potassium channel Kv1.3 mediates Bax-induced apoptosis in lymphocytes (Proceedings of Proceedings of the National Academy of Sciences of the United States of America, 105 45, 17586

Park M.H.;Lee J.Y.;Park K.H.;Jung I.K.;Kim K.T.;Lee Y.S.;Ryu H.H.;Jeong Y.;Kang M.;Schwaninger M.;Gulbins E.;Reichel M.;Kornhuber J.;Yamaguchi T.;Kim H.J.;Kim S.H.;Schuchman E.H.;Jin H.K.;Bae J.s. 11-07-2018. Erratum: Vascular and Neurogenic Rejuvenation in Aging Mice by Modulation of ASM (Neuron (2018) 100( Neuron, 100 3, 762

Baker J.;Boudreau R.;Seitz A.;Caldwell C.;Gulbins E.;Edwards M. 11-01-2018. Sphingolipids and innate immunity: A new approach to infection in the post-antibiotic era? Surgical Infections, 19 8, 792-803

Leanza L.;Zoratti M.;Gulbins E.;Szabò I. 11-01-2012. Induction of apoptosis in macrophages via Kv1.3 and Kv1.5 potassium channels Current Medicinal Chemistry, 19 31, 5394-5404

Riethmüller J.;Riehle A.;Grassmé H.;Gulbins E. 11-01-2007. Ceramide in Pseudomonas aeruginosa infections European Journal of Lipid Science and Technology, 109 10, 998-1002

Kornhuber J.;Medlin A.;Bleich S.;Jendrossek V.;Henkel A.;Wiltfang J.;Gulbins E. 11-01-2005. High activity of acid sphingomyelinase in major depression Journal of Neural Transmission, 112 11, 1583-1590

Rebillard A.;Rioux-Leclercq N.;Muller C.;Bellaud P.;Jouan F.;Meurette O.;Jouan E.;Vernhet L.;Le Quément C.;Carpinteiro A.;Schenck M.;Lagadic-Gossmann D.;Gulbins E.;Dimanche-Boitrel M. 10-30-2008. Acid sphingomyelinase deficiency protects from cisplatin-induced gastrointestinal damage Oncogene, 27 51, 6590-6595

Gulbins E.;Mark Coggeshall K.;Brenner B.;Schlottmann K.;Linderkamp O.;Langt F. 10-29-1996. Fas-induced apoptosis is mediated by activation of a Ras and Rac protein-regulated signaling pathway Journal of Biological Chemistry, 271 42, 26389-26394

Reichel M.;Rhein C.;Hofmann L.;Monti J.;Japtok L.;Langgartner D.;Füchsl A.;Kleuser B.;Gulbins E.;Hellerbrand C.;Reber S.;Kornhuber J. 10-16-2018. Chronic psychosocial stress in mice is associated with increased acid sphingomyelinase activity in l Frontiers in Psychiatry, 9 OCT,

Doering G.;Siegmann N.;Gulbins E. 10-14-2009. Ceramide accumulation causes inflammation in CF tissues Pediatric Pulmonology, 44 SUPPL. 32, 118

Gulbins E.;Becker K.A.;Zhang Y.;Doering G.;Riethmueller J. 10-14-2009. Therapeutic implications of ceramide accumulation and other basic features of ceramide in CF Pediatric Pulmonology, 44 SUPPL. 32, 114-115

Lang E.;Szabö I.;Ritter M.;Gulbins E. 10-12-1998. Cytosolic pH in regulation of cell proliferation and apoptotic cell death Acta Anaesthesiologica Scandinavica, Supplement, 42 112, 179-180

Park M.H.;Lee J.Y.;Park K.H.;Jung I.K.;Kim K.T.;Lee Y.S.;Ryu H.H.;Jeong Y.;Kang M.;Schwaninger M.;Gulbins E.;Reichel M.;Kornhuber J.;Yamaguchi T.;Kim H.J.;Kim S.H.;Schuchman E.H.;Jin H.K.;Bae J.s. 10-10-2018. Vascular and Neurogenic Rejuvenation in Aging Mice by Modulation of ASM Neuron, 100 1, 167-182.e9

Brenner B.;Koppenhoefer U.;Lepple-Wienhues A.;Grassmé H.;Müller C.;Speer C.;Lang F.;Gulbins E. 10-09-1997. The CD40 ligand directly activates T-Lymphocytes via tyrosine phosphorylation dependent PKC activati Biochemical and Biophysical Research Communications, 239 1, 11-17

Uhlemann A.;Brenner B.;Gulbins E.;Linderkamp O.;Lang F. 10-09-1997. Stimulation of TK1 lymphoma cells via ?<inf>4</inf>?<inf>7</inf> integrin re Biochemical and Biophysical Research Communications, 239 1, 68-73

Hauck C.R.;Gulbins E.;Lang F.;Meyer T.F. 10-07-1999. Tyrosine phosphatase SHP-1 is involved in CD66-mediated phagocytosis of Opa<inf>52</inf> Infection and Immunity, 67 10, 5490-5494

Wigger D.;Gulbins E.;Kleuser B.;Schumacher F. 10-01-2019. Monitoring the Sphingolipid de novo Synthesis by Stable-Isotope Labeling and Liquid Chromatography-M Frontiers in Cell and Developmental Biology, 7 ,

Managò A.;Leanza L.;Carraretto L.;Sassi N.;Grancara S.;Quintana-Cabrera R.;Trimarco V.;Toninello A.;Scorrano L.;Trentin L.;Semenzato G.;Gulbins E.;Zoratti M.;Szabò I. 10-01-2015. Early effects of the antineoplastic agent salinomycin on mitochondrial function Cell Death and Disease, 6 10,

Wieder T.;Lang P.;Lang K.;Kempe D.;Niemoeller O.;Duranton C.;Gulbins E.;Huber S.;Lang F. 10-01-2005. Studying mechanisms of eryptosis Cytotechnology, 49 2-3, 117-132

Lang F.;Szabo I.;Lepple-Wienhues A.;Siemen D.;Gulbins E. 10-01-1999. Physiology of receptor-mediated lymphocyte apoptosis News in Physiological Sciences, 14 5, 194-200

Gulbins E.;Brenner B.;Schlottmann K.;Koppenhoefer U.;Linderkamp O.;Coggeshall K.;Lang F. 10-01-1996. Activation of the Ras Signaling Pathway by the CD40 Receptor Journal of Immunology, 157 7, 2844-2850

Leanza L.;Biasutto L.;Managò A.;Gulbins E.;Zoratti M.;Szabò I. 09-30-2013. Intracellular ion channels and cancer Frontiers in Physiology, 4 SEP ,

Grassmé H.;Bock J.;Kun J.;Gulbins E. 09-27-2002. Erratum: Clustering of CD40 ligand is required to form a functional contact with CD40 (Journal of Bi Journal of Biological Chemistry, 277 39, 36904

Beckmann N.;Kadow S.;Schumacher F.;Göthert J.R.;Kesper S.;Draeger A.;Schulz-Schaeffer W.J.;Wang J.;Becker J.U.;Kramer M.;Kühn C.;Kleuser B.;Becker K.A.;Gulbins E.;Carpinteiro A. 09-25-2018. Pathological manifestations of Farber disease in a new mouse model Biological Chemistry, 399 10, 1183-1202

Bezgovsek J.;Gulbins E.;Friedrich S.;Lang K.;Duhan V. 09-25-2018. Sphingolipids in early viral replication and innate immune activation Biological Chemistry, 399 10, 1115-1123

Carpinteiro A.;Becker K.;Gulbins E. 09-25-2018. Highlight: Sphingolipids in infectious biology and immunology Biological Chemistry, 399 10, 1113

Wu Y.;Gulbins E.;Grassmé H. 09-25-2018. The function of sphingomyelinases in mycobacterial infections Biological Chemistry, 399 10, 1125-1133

Koppenhoefer U.;Brenner B.;Lang F.;Gulbins E. 09-08-1997. The CD40-ligand stimulates T-lymphocytes via the neutral sphingomyelinase: A novel function of the C FEBS Letters, 414 2, 444-448

Szabò I.;Gulbins E.;Apfel H.;Zhang X.;Barth P.;Busch A.;Schlottmann K.;Pongs O.;Lang F. 09-05-1996. Tyrosine phosphorylation-dependent suppression of a voltage-gated K⁺ channel Journal of Biological Chemistry, 271 34, 20465-20469

Belka C.;Marini P.;Lepple-Wienhues A.;Budach W.;Jekle A.;Los M.;Lang F.;Schulze-Osthoff K.;Gulbins E.;Bamberg M. 09-02-1999. The tyrosine kinase Lck is required for CD95-independent caspase-8 activation and apoptosis in respo Oncogene, 18 35, 4983-4992

Neuber C.;Schumacher F.;Gulbins E.;Kleuser B. 09-01-2014. Method to simultaneously determine the sphingosine 1-Phosphate breakdown product (2E)?Hexadecenal an Analytical Chemistry, 86 18, 9065-9073

Schenck M.;Boergermann C.;Vom Dorp F.;Busch Y.;Groneberg M.;Wilker B.;Keitsch S.;Moyrer S.;Schmid K.W.;Stuschke M.;Ruebben H.;Gulbins E. 09-01-2007. Identification of the molecular basis of metastasizing for the development of new therapeutic strate Urologe - Ausgabe A, 46 9, 1261-1262

Schenck M.;Börgermann C.;Vom Dorp F.;Groneberg M.;Busch Y.;Carpinteiro A.;Wilker B.;Keitsch S.;Moyrer S.;Schmid K.W.;Stuschke M.;Rübben H.;Gulbins E. 09-01-2007. Proapoptotic antibodies as new therapeutic agents for tumor treatment Urologe - Ausgabe A, 46 9, 1262-1265

Schenck M.;Vom Dorp F.;Boergermann C.;Busch Y.;Carpinteiro A.;Wilker B.;Keitsch S.;Schmid K.W.;Groneberg M.;Stuschke M.;Ruebben H.;Gulbins E. 09-01-2007. Founding a working group "lymph node metastases" at the West German Cancer Center (WTZE), University Urologe - Ausgabe A, 46 9, 1257-1260

Kirschnek S.;Paris F.;Weller M.;Grassmé H.;Ferlinz K.;Riehle A.;Fuks Z.;Kolesnick R.;Gulbins E. 09-01-2000. CD95-mediated apoptosis in vivo involves acid sphingomyelinase Journal of Biological Chemistry, 275 35, 27316-27323

Gulbins E.;Hoffend J.;Zou A.;Dietrich M.;Schlottmann K.;Cavarape A.;Steinhausen M. 09-01-1993. Endothelin and endothelium?derived relaxing factor control of basal renovascular tone in hydronephro The Journal of Physiology, 469 1, 571-582

Geng Y.;Gulbins E.;Altman A.;Lotz M. 08-30-1994. Monocyte deactivation by interleukin 10 via inhibition of tyrosine kinase activity and the Ras signa Proceedings of the National Academy of Sciences of the United States of America, 91 18, 8602-8606

Brenner B.;Koppenhoefer U.;Weinstock C.;Linderkamp O.;Lang F.;Gulbins E. 08-29-1997. Fas- or ceramide-induced apoptosis is mediated by a Rac1-regulated activation of Jun N-terminal kina Journal of Biological Chemistry, 272 35, 22173-22181

Brenner B.;Grassmé H.;Müller C.;Lang F.;Speer C.;Gulbins E. 08-25-1998. L-selectin stimulates the neutral sphingomyelinase and induces release of ceramide Experimental Cell Research, 243 1, 123-128

Hauck C.;Grassmé H.;Bock J.;Jendrossek V.;Ferlinz K.;Meyer T.;Gulbins E. 08-04-2000. Acid sphingomyelinase is involved in CEACAM receptor-mediated phagocytosis of Neisseria gonorrhoeae FEBS Letters, 478 3, 260-266

Seitz A.P.;Schumacher F.;Baker J.;Soddemann M.;Wilker B.;Caldwell C.C.;Gobble R.M.;Kamler M.;Becker K.A.;Beck S.;Kleuser B.;Edwards M.J.;Gulbins E. 08-01-2019. Sphingosine-coating of plastic surfaces prevents ventilator-associated pneumonia Journal of Molecular Medicine, 97 8, 1195-1211

Leanza L.;Trentin L.;Becker K.;Frezzato F.;Zoratti M.;Semenzato G.;Gulbins E.;Szabo I. 08-01-2013. Clofazimine, Psora-4 and PAP-1, inhibitors of the potassium channel Kv1.3, as a new and selective th Leukemia, 27 8, 1782-1785

Hassan M.;Alaoui A.;Feyen O.;Mirmohammadsadegh A.;Essmann F.;Tannapfel A.;Gulbins E.;Schulze-Osthoff K.;Hengge U. 07-31-2008. The BH3-only member Noxa causes apoptosis in melanoma cells by multiple pathways Oncogene, 27 33, 4557-4568

Lang F.;Madlung J.;Uhlemann A.;Risler T.;Gulbins E. 07-27-1998. Cellular taurine release triggered by stimulation of the Fas(CD95) receptor in Jurkat lymphocytes Pflugers Archiv European Journal of Physiology, 436 3, 377-383

Gulbins E.;Welsch J.;Lepple-Wienhuis A.;Heinle H.;Lang F. 07-18-1997. Inhibition of Fas-induced apoptotic cell death by osmotic cell shrinkage Biochemical and Biophysical Research Communications, 236 2, 517-521

Röhn T.;Wagenknecht B.;Roth W.;Naumann U.;Gulbins E.;Krammer P.;Walczak H.;Weller M. 07-12-2001. CCNU-dependent potentiation of TRAIL/Apo2L-induced apoptosis in human glioma cells is p53-independen Oncogene, 20 31, 4128-4137

Wagenknecht B.;Roth W.;Gulbins E.;Wolburg H.;Weller M. 07-09-2001. C2-ceramide signalling in glioma cells: Synergistic enhancement of CD95-mediated, caspase-dependent Cell Death and Differentiation, 8 6, 595-602

Gulbins E.;Szabo I.;Baltzer K.;Lang F. 07-08-1997. Ceramide-induced inhibition of T lymphocyte voltage-gated potassium channel is mediated by tyrosine Proceedings of the National Academy of Sciences of the United States of America, 94 14, 7661-7666

Vom Dorp F.;Wullich B.;Gulbins E.;Eisenhardt A. 07-01-2005. Molecular biology approach to explain lymphatic metastasis Urologe - Ausgabe A, 44 6, 608-613

Cremesti A.;Paris F.;Grassmé H.;Holler N.;Tschopp J.;Fuks Z.;Gulbins E.;Kolesnick R. 06-29-2001. Ceramide Enables Fas to Cap and Kill Journal of Biological Chemistry, 276 26, 23954-23961

Roller A.;Bähr O.;Streffer J.;Winter S.;Heneka M.;Deininger M.;Meyermann R.;Naumann U.;Gulbins E.;Weller M. 06-16-1999. Selective potentiation of drug cytotoxicity by NSAID in human glioma cells: The role of COX-1 and MR Biochemical and Biophysical Research Communications, 259 3, 600-605

Grassmé H.;Jekle A.;Riehle A.;Schwarz H.;Berger J.;Sandhoff K.;Kolesnick R.;Gulbins E. 06-08-2001. CD95 Signaling via Ceramide-rich Membrane Rafts Journal of Biological Chemistry, 276 23, 20589-20596

Jekle A.;Obst R.;Lang F.;Rammensee H.;Gulbins E. 06-07-2000. CD95/CD95 ligand-mediated counterattack does not block T cell cytotoxicity Biochemical and Biophysical Research Communications, 272 2, 395-399

Wagenknecht B.;Gulbins E.;Lang F.;Dichgans J.;Weller M. 06-02-1997. Lipoxygenase inhibitors block CD95 ligand-mediated apoptosis of human malignant glioma cells FEBS Letters, 409 1, 17-23

Brown M.B.;Hunt W.R.;Noe J.E.;Rush N.I.;Schweitzer K.S.;Leece T.C.;Moldobaeva A.;Wagner E.M.;Dudek S.M.;Poirier C.;Presson R.G.;Gulbins E.;Petrache I. 06-01-2014. Loss of cystic fibrosis transmembrane conductance regulator impairs lung endothelial cell barrier fu Pulmonary Circulation, 4 2, 260-268

Becker K.;Riethmüller J.;Döring G.;Gulbins E. 06-01-2009. Molecular medicine: Cystic fibrosis - Pathophysiological concepts BioSpektrum, 15 4, 383-385

Lang F.;Föller M.;Lang K.;Lang P.;Ritter M.;Gulbins E.;Vereninov A.;Huber S. 06-01-2005. Ion channels in cell proliferation and apoptotic cell death Journal of Membrane Biology, 205 3, 147-157

Szabò I.;Adams C.;Gulbins E. 06-01-2004. Ion channels and membrane rafts in apoptosis Pflugers Archiv European Journal of Physiology, 448 3, 304-312

Kullmann S.;Teichgrüher V.;Bollinger C.;Gulbins E. 05-26-2008. Ceramide Signaling in Apoptosis and Cancer Therapy Apoptosis and Cancer Therapy: From Cutting-edge Science to Novel Therapeutic Concepts, 2 , 997-1013

Lang F.;Madlung J.;Siemen D.;Ellory C.;Lepple-Wienhues A.;Gulbins E. 05-26-2000. The involvement of caspases in the CD95(Fas/Apo-1)- but not swelling- induced cellular taurine relea Pflugers Archiv European Journal of Physiology, 440 1, 93-99

Szabò I.;Lepple-Wienhues A.;Kaba K.;Zorattii M.;Gulbins E.;Lang F. 05-26-1998. Tyrosine kinase-dependent activation of a chloride channel in CD95-induced apoptosis in T lymphocyte Proceedings of the National Academy of Sciences of the United States of America, 95 11, 6169-6174

Sammar M.;Gulbins E.;Hilbert K.;Lang F.;Altevogt P. 05-19-1997. Mouse CD24 as a signaling molecule for integrin-mediated cell binding: Functional and physical assoc Biochemical and Biophysical Research Communications, 234 2, 330-334

Hassan M.;Alaoui A.;Feyen O.;Mirmohammadsadegh A.;Essmann F.;Tannapfel A.;Gulbins E.;Schulze-Osthoff K.;Hengge U.R. 04-28-2011. Erratum: The BH3-only member Noxa causes apoptosis in melanoma cells by multiple pathways (Oncogene Oncogene, 30 17, 2086

Siemen D.;Loupatatzis C.;Borecky J.;Gulbins E.;Lang F. 04-13-1999. Ca²⁺-activated K channel of the BK-type in the inner mitochondrial membrane o Biochemical and Biophysical Research Communications, 257 2, 549-554

Lepple-Wienhues A.;Szabò I.;Laun T.;Kaba N.;Gulbins E.;Lang F. 04-06-1998. The tyrosine kinase p56(lck) mediates activation of swelling-induced chloride channels in lymphocyte Journal of Cell Biology, 141 1, 281-286

Jendrossek V.;Grassmé H.;Mueller I.;Lang F.;Gulbins E. 04-05-2001. Pseudomonas aeruginosa-induced apoptosis involves mitochondria and stress-activated protein kinases Infection and Immunity, 69 4, 2675-2683

Li C.;Wu Y.;Riehle A.;Orian-Rousseau V.;Zhang Y.;Gulbins E.;Grassmé H. 04-01-2018. Regulation of staphylococcus aureus infection of macrophages by CD44, reactive oxygen species, and a Antioxidants and Redox Signaling, 28 10, 916-934

Wu Y.;Gulbins E.;Grassmé H. 04-01-2018. Crosstalk between sphingomyelinases and reactive oxygen species in mycobacterial infection Antioxidants and Redox Signaling, 28 10, 935-948

Junge S.;Brenner B.;Lepple-Wienhues A.;Nilius B.;Lang F.;Linderkamp O.;Gulbins E. 04-01-1999. Intracellular mechanisms of L-selectin induced capping Cellular Signalling, 11 4, 301-308

Paris F.;Grassmé H.;Cremesti A.;Zager J.;Fong Y.;Haimovitz-Friedman A.;Fuks Z.;Gulbins E.;Kolesnick R. 03-16-2001. Natural Ceramide Reverses Fas Resistance of Acid Sphingomyelinase ^-/- Hepatoc Journal of Biological Chemistry, 276 11, 8297-8305

Baier G.;Telford D.;Gulbins E.;Yamada N.;Kawakami T.;Altman A. 03-11-1993. Improved specificity of RT-PCR amplifications using nested cDNA primers Nucleic Acids Research, 21 5, 1329-1330

Szabó I.;Nilius B.;Zhang X.;Busch A.;Gulbins E.;Suessbrich H.;Lang F. 03-08-1997. Inhibitory effects of oxidants on n-type K⁺ channels in T lymphocytes and Xen Pflugers Archiv European Journal of Physiology, 433 5, 626-632

Baier-Bitterlich G.;Baicr G.;Gulbins E.;Mark Coggeshall K.;Altman A. 03-03-1995. Thf role of p56^lck in cd4-mediated suppression of cd3-induced early signaling Life Sciences, 56 15, 1287-1297

Böll S.;Ziemann S.;Ohl K.;Klemm P.;Rieg A.D.;Gulbins E.;Becker K.A.;Kamler M.;Wagner N.;Uhlig S.;Martin C.;Tenbrock K.;Verjans E. 03-01-2020. Acid sphingomyelinase regulates T<inf>H</inf>2 cytokine release and bronchial asthma Allergy: European Journal of Allergy and Clinical Immunology, 75 3, 603-615

Kalinichenko L.S.;Hammad L.;Reichel M.;Kohl Z.;Gulbins E.;Kornhuber J.;Müller C.P. 03-01-2019. Acid sphingomyelinase controls dopamine activity and responses to appetitive stimuli in mice Brain Research Bulletin, 146 , 310-319

Neuber C.;Schumacher F.;Gulbins E.;Kleuser B. 03-01-2017. Mass spectrometric determination of fatty aldehydes exemplified by monitoring the oxidative degradat Neuromethods, 125 , 147-158

Szabò I.;Soddemann M.;Leanza L.;Zoratti M.;Gulbins E. 03-01-2011. Single-point mutations of a lysine residue change function of Bax and Bcl-x<inf>L</inf> Cell Death and Differentiation, 18 3, 427-438

Schenck M.;Vom Dorp F.;Boergermann C.;Rübben H.;Gulbins E. 03-01-2009. Temsirolimus - Trade name: Torisel Tagliche Praxis, 50 1, 163-168

Schenck M.;Vom Dorp F.;Boergermann C.;Rübben H.;Gulbins E. 03-01-2009. Temsirolimus - Trade name: Torisel Internistische Praxis, 49 1, 163-168

Grassmé H.;Jendrossek V.;Riehle A.;Von Kürthy G.;Berger J.;Schwarz H.;Weller M.;Kolesnick R.;Gulbins E. 03-01-2003. Host defense against Pseudomonas aeruginosa requires ceramide-rich membrane rafts Nature Medicine, 9 3, 322-330

Gulbins E.;Langlet C.;Baier G.;Bonnefoy-Berard N.;Herbert E.;Altman A.;Coggeshall K. 03-01-1994. Tyrosine phosphorylation and activation of Vav GTP/GDP exchange activity in antigen receptor-trigger Journal of Immunology, 152 5, 2123-2129

Lozano J.;Morales A.;Cremesti A.;Fuks Z.;Tilly J.;Schuchman E.;Gulbins E.;Kolesnick R. 02-28-2001. Niemann-Pick Disease versus acid sphingomyelinase deficiency [1] Cell Death and Differentiation, 8 1, 100-102

Busch A.;Waldegger S.;Herzer T.;Raber G.;Gulbins E.;Takumi T.;Moriyoshi K.;Nakanishi S.;Lang F. 02-28-1995. Molecular basis of I(sK) protein regulation by oxidation or chelation Journal of Biological Chemistry, 270 8, 3638-3641

Gulbins E.;Hermisson M.;Brenner B.;Grassmé H.;Linderkamp O.;Dichgans J.;Weller M.;Lang F. 02-26-1998. Cellular stimulation via CD95 involves activation of phospho-inositide-3-kinase Pflugers Archiv European Journal of Physiology, 435 4, 546-554

Brenner B.;Gulbins E.;Busch G.;Koppenhoefer U.;Lang F.;Linderkamp O. 02-24-1997. L-selectin regulates actin polymerisation via activation of the small G-protein Rac2 Biochemical and Biophysical Research Communications, 231 3, 802-807

Kissling G.;Blickle B.;Ross C.;Pascht U.;Gulbins E. 02-15-1997. ?-Adrenoceptor-mediated negative inotropy of adrenaline in rat myocardium Journal of Physiology, 499 1, 195-205

Johnson K.T.M.;Wiesweg B.;Schott M.;Ehlers M.;Müller M.;Minich W.B.;Nagayama Y.;Gulbins E.;Eckstein A.K.;Berchner-Pfannschmidt U. 02-08-2013. Examination of orbital tissues in murine models of graves' disease reveals expression of UCP-1 and t Hormone and Metabolic Research, 45 6, 401-407

Raber G.;Waldegger S.;Herzer T.;Gulbins E.;Murer H.;Busch A.;Lang F. 02-06-1995. The nitroso-donor s-nitrosocysteine regulates i<inf>sK</inf> expressed in Xenopus oocyte Biochemical and Biophysical Research Communications, 207 1, 195-201

Beck S.;Sehl C.;Voortmann S.;Verhasselt H.;Edwards M.;Buer J.;Hasenberg M.;Gulbins E.;Becker K. 02-01-2020. Sphingosine is able to prevent and eliminate Staphylococcus epidermidis biofilm formation on differe Journal of Molecular Medicine, 98 2, 209-219

Bodas M.;Pehote G.;Silverberg D.;Gulbins E.;Vij N. 02-01-2019. Autophagy augmentation alleviates cigarette smoke-induced CFTR-dysfunction, ceramide-accumulation an Free Radical Biology and Medicine, 131 , 81-97

Esen M.;Grassmé H.;Riethmüller J.;Riehle A.;Fassbender K.;Gulbins E. 01-16-2001. Invasion of human epithelial cells by Pseudomonas aeruginosa involves Src-like tyrosine kinases p60S Infection and Immunity, 69 1, 281-287

Hauck C.;Meyer T.;Lang F.;Gulbins E. 01-15-1998. CD66-mediated phagocytosis of Opa<inf>52</inf> Neisseria gonorrhoeae requires a Src-like EMBO Journal, 17 2, 443-454

Fukamachi H.;Yamada N.;Miura T.;Kato T.;Ishikawa M.;Gulbins E.;Altman A.;Kawakami Y.;Kawakami T. 01-15-1994. Identification of a protein, SPY75, with repetitive helix-turn-helix motifs and an SH3 domain as a m Journal of Immunology, 152 2, 642-652

Becker K.A.;Uerschels A.K.;Goins L.;Doolen S.;McQuerry K.J.;Bielawski J.;Sure U.;Bieberich E.;Taylor B.K.;Gulbins E.;Spassieva S.D. 01-01-2020. Role of 1-Deoxysphingolipids in docetaxel neurotoxicity Journal of Neurochemistry, ,

Kalinichenko L.;Gulbins E.;Kornhuber J.;Müller C. 01-01-2020. Serotonin – lipid interactions and their role in behavior Handbook of Behavioral Neuroscience, 31 , 289-308

Baduva K.;Büchter L.;Kreyenkamp K.;Westphal L.;Wilker B.;Kohnen M.;Schuchman E.;Edwards M.;Becker K.;Gulbins E.;Carpinteiro A. 01-01-2019. Signalling effects induced by acid ceramidase in human epithelial or leukemic cell lines Cellular Physiology and Biochemistry, 52 5, 1092-1102

Carstens H.;Schumacher F.;Keitsch S.;Kramer M.;Kühn C.;Sehl C.;Soddemann M.;Wilker B.;Herrmann D.;Swaidan A.;Kleuser B.;Verhaegh R.;Hilken G.;Edwards M.J.;Dubicanac M.;Carpinteiro A.;Wissmann A.;Becker K.A.;Kamler M.;Gulbins E. 01-01-2019. Clinical Development of Sphingosine as Anti-Bacterial Drug: Inhalation of Sphingosine in Mini Pigs h Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 53 6, 1015-1028

Kalinichenko L.;Mühle C.;Eulenburg V.;Praetner M.;Reichel M.;Gulbins E.;Kornhuber J.;Müller C. 01-01-2019. Enhanced alcohol preference and anxiolytic alcohol effects in Niemann-Pick disease model in mice Frontiers in Neurology, 10 JUL,

Li C.;Wang A.;Wu Y.;Gulbins E.;Grassmé H.;Zhao Z. 01-01-2019. Acid sphingomyelinase-ceramide system in bacterial infections Cellular Physiology and Biochemistry, 52 2, 280-301

Walter S.;Gulbins E.;Halmer R.;Jahromi N.H.;Becker K.A.;Schottek A.;Blatti C.;Davies L.;Schnoeder L.;Bertsch T.;Engelhardt B.;Fassbender K. 01-01-2019. Pharmacological Inhibition of Acid Sphingomyelinase Ameliorates Experimental Autoimmune Encephalomye Neuro-Signals, 27 S1, 20-31

Xia B.;Beckmann N.;Winer L.;Pugh A.;Pritts T.;Nomellini V.;Gulbins E.;Caldwell C. 01-01-2019. Amitriptyline reduces inflammation and mortality in a murine model of sepsis Cellular Physiology and Biochemistry, 52 3, 565-579

Zoicas I.;Huber S.;Kalinichenko L.;Gulbins E.;Müller C.;Kornhuber J. 01-01-2019. Ceramides affect alcohol consumption and depressive-like and anxiety-like behavior in a brain region Addiction Biology, ,

Hoehn R.;Monse M.;Pohl E.;Wranik S.;Wilker B.;Keitsch S.;Soddemann M.;Kornhuber J.;Kohnen M.;Edwards M.;Grassme H.;Gulbins E. 01-01-2016. Melatonin acts as an antidepressant by inhibition of the acid sphingomyelinase/ ceramide system NeuroSignals, 24 1, 48-58

Quillin R.;Wilson G.;Nojima H.;Freeman C.;Wang J.;Schuster R.;Blanchard J.;Edwards M.;Gandhi C.;Gulbins E.;Lentsch A. 01-01-2015. Inhibition of acidic sphingomyelinase reduces established hepatic fibrosis in mice Hepatology Research, 45 3, 305-314

Beckmann N.;Sharma D.;Gulbins E.;Becker K.A.;Edelmann B. 01-01-2014. Inhibition of acid sphingomyelinase by tricyclic antidepressants and analogons Frontiers in Physiology, 5 AUG ,

Münzer P.;Borst O.;Walker B.;Schmid E.;Feijge M.;Cosemans J.;Chatterjee M.;Schmidt E.;Schmidt S.;Towhid S.;Leibrock C.;Elvers M.;Schaller M.;Seizer P.;Ferlinz K.;May A.;Gulbins E.;Heemskerk J.;Gawaz M.;Lang F. 01-01-2014. Acid sphingomyelinase regulates platelet cell membrane scrambling, secretion, and thrombus formation Arteriosclerosis, Thrombosis, and Vascular Biology, 34 1, 61-71

Schneider-Schaulies S.;Müller N.;Gulbins E. 01-01-2014. Membrane microdomains enriched in ceramides from generation to function Cell Membrane Nanodomains: From Biochemistry to Nanoscopy, , 133-172

Yang W.;Schmid E.;Nurbaeva M.;Szteyn K.;Leibrock C.;Yan J.;Schaller M.;Gulbins E.;Shumilina E.;Lang F. 01-01-2014. Role of acid sphingomyelinase in the regulation of mast cell function Clinical and Experimental Allergy, 44 1, 79-90

Becker K.;Riethmüller J.;Zhang Y.;Gulbins E. 01-01-2010. The role of sphingolipids and ceramide in pulmonary inflammation in cystic fibrosis Open Respiratory Medicine Journal, 4 , 39-47

Schenck M.;Ruebben H.;Gulbins E. 01-01-2009. Molecular aspects of lymph node metastasis Urologe - Ausgabe A, 48 1, 6-11

Fassbender K.;Walter S.;Kühl S.;Landmann R.;Ishii K.;Bertsch T.;Stalder A.K.;Muehlhauser F.;Liu Y.;Ulmer A.J.;Rivest S.;Lentschat A.;Gulbins E.;Jucker M.;Staufenbiel M.;Brechtel K.;Walter J.;Multhaup G.;Penke B.;Adachi Y.;Hartmann T.;Beyreuther K. 01-01-2004. The LPS receptor (CD14) links innate immunity with Alzheimer's disease. The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 18 1, 203-205

Grassmé H.;Jendrossek V.;Gulbins E. 01-01-2001. Molecular mechanisms of bacteria induced apoptosis Apoptosis, 6 6, 441-445

Grassmé H.;Schwarz H.;Gulbins E. 01-01-2001. Molecular mechanisms of ceramide-mediated CD95 clustering Biochemical and Biophysical Research Communications, 284 4, 1016-1030

Gulbins E.;Lang F. 01-01-2001. Pathogens, host-cell invasion and disease American Scientist, 89 5, 406-413

Gulbins E.;Kolesnick R. 01-01-2000. Measurement of sphingomyelinase activity Methods in Enzymology, 322 , 382-388

Lang F.;Madlung J.;Bock J.;Lükewille U.;Kaltenbach S.;Lang K.S.;Belka C.;Wagner C.A.;Lang H.J.;Gulbins E.;Lepple-Wienhues A. 01-01-2000. Inhibition of Jurkat-T-lymphocyte Na⁺/H⁺-exchanger by Pflugers Archiv European Journal of Physiology, 440 6, 902-907

Lang F.;Ritter M.;Gamper N.;Huber S.;Fillon S.;Tanneur V.;Lepple-Wienhues A.;Szabo I.;Gulbins E. 01-01-2000. Cell volume in the regulation of cell proliferation and apoptotic cell death Cellular Physiology and Biochemistry, 10 5-6, 417-428

Lepple-Wienhues A.;Szabò I.;Wieland U.;Heil L.;Gulbins E.;Lang F. 01-01-2000. Tyrosine kinases open lymphocyte chloride channels Cellular Physiology and Biochemistry, 10 5-6, 307-312

Uhlemann A.;Müller C.;Madlung J.;Gulbins E.;Lang F. 01-01-2000. Inhibition of CD95/Fas-induced DNA degradation by osmotic cell shrinkage Cellular Physiology and Biochemistry, 10 4, 219-228

Lang F.;Uhlernann A.;Lepple-Wienhues A.;Szabo I.;Siemen D.;Nilius B.;Gulbins E. 01-01-1999. Cell volume regulatory mechanisms in apoptotic cell death Herz, 24 3, 232-235

Belka C.;Marini P.;Budach W.;Schulze-Osthoff K.;Lang F.;Gulbins E.;Bamberg M. 01-01-1998. Radiation-induced apoptosis in human lymphocytes and lymphoma cells critically relies on the up-regu Radiation Research, 149 6, 588-595

Brenner B.;Ferlinz K.;Grassmé H.;Weller M.;Koppenhoefer U.;Dichgans J.;Sandhoff K.;Lang F.;Gulbins E. 01-01-1998. Fas/CD95/Apo-I activates the acidic sphingomyelinase via caspases Cell Death and Differentiation, 5 1, 29-37

Brenner B.;Gulbins E.;Koppenhoefer U.;Lang F.;Linderkamp O. 01-01-1998. Dual function of the cd40 ligand (gp39) for t- and b-lymphocytes Pediatric Research, 44 3, 428

Brenner B.;Gulbins E.;Weinmann S.;Lang F.;Linderkamp O. 01-01-1998. Pleiotropic signalling functions of the adhesion molecule l-selectin Pediatric Research, 44 3, 428

Gulbins E.;Brenner B.;Koppenhoefer U.;Linderkamp O.;Lang F. 01-01-1998. Fas or ceramide induce apoptosis by Ras-regulated phosphoinositide-3- kinase activation Journal of Leukocyte Biology, 63 2, 253-263

Lang F.;Busch G.L.;Ritter M.;Völkl H.;Waldegger S.;Gulbins E.;Häussinger D. 01-01-1998. Functional significance of cell volume regulatory mechanisms Physiological Reviews, 78 1, 247-306

Lang F.;Lepple-Wienhues A.;Paulmichl M.;Szabo I.;Siemen D.;Gulbins E. 01-01-1998. Ion channels, cell volume, and apoptotic cell death Cellular Physiology and Biochemistry, 8 6, 285-292

Linderkamp O.;Ruef P.;Brenner B.;Gulbins E.;Lang F. 01-01-1998. Passive deformability of mature, immature, and active neutrophils in healthy and septicemic neonates Pediatric Research, 44 6, 946-950

Ständer M.;Naumann U.;Dumitrescu L.;Heneka M.;Löschmann P.;Gulbins E.;Dichgans J.;Weller M. 01-01-1998. Decorin gene transfer-mediated suppression of TGF-? synthesis abrogates experimental malignant gliom Gene Therapy, 5 9, 1187-1194

Trepel M.;Groscurth P.;Malipiero U.;Gulbins E.;Dichgans J.;Weller M. 01-01-1998. Chemosensitivity of human malignant glioma: Modulation by p53 gene transfer Journal of Neuro-Oncology, 39 1, 19-32

Wagenknecht B.;Schulz J.;Gulbins E.;Weller M. 01-01-1998. Crm-A, bcl-2 and NDGA inhibit CD95L-induced apoptosis of malignant glioma cells at the level of casp Cell Death and Differentiation, 5 10, 894-900

Brenner B.;Gulbins E.;Koppenhoefer U.;Lang F.;Linderkamp O. 01-01-1997. L-selectin-mediated lymphocyte rolling of jurkat T lymphocytes depends on functional expression of t Cellular Physiology and Biochemistry, 7 2, 107-118

Brenner B.;Weinmann S.;Grassmé H.;Lang F.;Linderkamp O.;Gulbins E. 01-01-1997. L-selectin activates JNK via src-like tyrosine kinases and the small G-protein Rac Immunology, 92 2, 214-219

Szabö I.;Gulbins E.;Lang F. 01-01-1997. Regulation of Kv1.3 during fas-induced apoptosis Cellular Physiology and Biochemistry, 7 3-4, 148-158

Wagenknecht B.;Trepel M.;Deimling A.;Grimmei C.;Rollbrocke B.;Hayash Y.;Lang F.;Dichgans J.;Gulbins E.;Weller M. 01-01-1997. p53 accumulation promotes dephosphorylation and proteolytic cleavage of retinoblastoma protein in hu Cellular Physiology and Biochemistry, 7 6, 304-311

Weller M.;Weinstock C.;Will C.;Wagenknecht B.;Dichgans J.;Lang F.;Gulbins E. 01-01-1997. CD95-Dependent T-Cell Killing by Glioma Cells Expressing CD95 Ligand: More on Tumor Immune Escape, t Cellular Physiology and Biochemistry, 7 5, 282-288

Gulbins E.;Brenner B.;Schlottmann K.;Welsch J.;Heinle H.;Koppenhoefer U.;Linderkamp O.;Coggeshall K.;Lang F. 01-01-1996. Fas-induced programmed cell death is mediated by a Ras-regulated O<inf>2</inf><sup> Immunology, 89 2, 205-212

Gulbins E.;Schlottmann K.;Brenner B.;Linderkamp O.;Lang F.;Coggeshall K. 01-01-1996. Erratum: Molecular analysis of ras activation by tyrosine phosphorylated vav (Biochemical and Biophy Biochemical and Biophysical Research Communications, 221 1, 205

Gulbins E.;Szabo I.;Lang F. 01-01-1996. Physiology of fas-induced programmed cell death Cellular Physiology and Biochemistry, 6 6, 361-375

Schlottmann K.;Gulbins E.;Lau S.;Coggeshall K. 01-01-1996. Activation of Src-family tyrosine kinases during fas-induced apoptosis Journal of Leukocyte Biology, 60 4, 546-554

Gulbins E.;Bissonnette R.;Mahboubi A.;Martin S.;Nishloka W.;Brunner T.;Baier G.;Baler-Bltterlich G.;Byrd C.;Lang F.;Kolesnick R.;Altman A.;Green D. 01-01-1995. FAS-induced apoptosis is mediated via a ceramide-initiated RAS signaling pathway Immunity, 2 4, 341-351

Gulbins E.;Brenner B.;Lang F. 01-01-1995. Molecular mechanisms of lymphocyte activation Nephrology Dialysis Transplantation, 10 9, 1533-1535

Lang F.;Busch G.;Gulbins E. 01-01-1995. Physiology of cell survival and cell death: Implications for organ conservation Nephrology Dialysis Transplantation, 10 9, 1551-1555

Waldegger S.;Schmidt F.;Herzer T.;Gulbins E.;Schuster A.;Biber J.;Markovich D.;Murer H.;Busch A.;Lang F. 01-01-1995. Heavy metal mediated inhibition of rBAT-induced amino acid transport Kidney International, 47 6, 1677-1681

Zornig M.;Busch G.;Beneke R.;Gulbins E.;Lang F.;Ma A.;Korsmeyer S.;Moroy T. 01-01-1995. Survival and death of prelymphomatous B-cells from N-myc/bcl-2 double transgenic mice correlates wit Oncogene, 11 10, 2165-2174

Cavarape A.;Hoffend J.;Gulbins E.;Bartoli E.;Steinhausen M. 01-01-1994. Role of endothelin and endothelium-derived relaxing factor in renal microcirculation Giornale Italiano di Nefrologia, 11 5, 341-349

Gulbins E.;Coggeshall K.;Baier G.;Telford D.;Langlet C.;Baier-Bitterlich G.;Bonnefoy-Berard N.;Burn P.;Wittinghofer A.;Altman A. 01-01-1994. Direct stimulation of Vav guanine nucleotide exchange activity for Ras by phorbol esters and diglyce Molecular and Cellular Biology, 14 7, 4749-4758

Gulbins E.;Coggeshall K.;Langlet C.;Baier G.;Bonnefoy-Berard N.;Burn P.;Wittinghofer A.;Katzav S.;Altman A. 01-01-1994. Activation of Ras in vitro and in intact fibroblasts by the Vav guanine nucleotide exchange protein Molecular and Cellular Biology, 14 2, 906-913

SCHLOTTMANN K.;GULBINS E.;RAUTERBERG E.;STEINHAUSEN M. 01-01-1994. Effects of systemic complement activation on renal circulation of rats European Journal of Clinical Investigation, 24 5, 320-330

Gulbins E.;Coggeshall K.;Baier G.;Katzav S.;Burn P.;Altman A. 01-01-1993. Tyrosine kinase-stimulated guanine nucleotide exchange activity of Vav in T cell activation Science, 260 5109, 822-825

Gulbins E.;Schlottmann K.;Rauterberg E.W.;Steinhausen M. 01-01-1993. Effects of rC5a on the circulation of normal and split hydronephrotic rat kidneys American Journal of Physiology - Renal Fluid and Electrolyte Physiology, 265 1 34-1,

Gulbins E.;Siow Y.;Vitale G. 01-01-1993. Complement 5a induces in vivo synthesis of cysteinyl leukotrienes in rats Prostaglandins, Leukotrienes and Essential Fatty Acids, 48 4, 331-334

Keilholz U.;Schlottmann K.;Dummer R.;Link H.;Gulbins E.;Steinhausen M.;Hunstein W. 01-01-1993. Mechanism and clinical management of interleukin-2-induced renal toxicity and fluid retention International Journal of Immunopathology and Pharmacology, 6 1, 1-11

Fretschner M.;Endlieh K.;Gulbins E.;Lang R.;Schlottmann K.;Steinhausen M. 01-01-1991. Effects of endothelin on the renal microcirculation of the split hydronephrotic rat kidney Kidney and Blood Pressure Research, 14 3, 112-127

GULBINS E.;PAREKH N.;RAUTERBERG E.;SCHLOTTMANN K.;STEINHAUSEN M. 01-01-1991. Cysteinyl leukotriene actions on the microcirculation of the normal and split hydronephrotic rat kid European Journal of Clinical Investigation, 21 2, 184-196