Aaron P. Seitz, MD

Niziolek, Grace M; Hoehn, Richard S; Seitz, Aaron P; Jernigan, Peter L; Makley, Amy T; Gulbins, Erich; Edwards, Michael J; Goodman, Michael D 2021. The Role of Acid Sphingomyelinase Inhibition in Repetitive Mild Traumatic Brain Injury. The Journal of surgical research, 259 , 296-304

Seitz, Aaron; Baker, Jennifer E; Levinsky, Nick C; Morris, Mackenzie C; Edwards, Michael J; Gulbins, Erich; Blakeman, Thomas C; Rodriquez, Dario; Branson, Richard D; Goodman, Michael 2021. Antimicrobial coating prevents ventilator-associated pneumonia in a 72 hour large animal model. The Journal of surgical research, 267 , 424-431

Baker, Jennifer E; Seitz, Aaron P; Boudreau, Ryan M; Skinner, Mitchell J; Beydoun, Ahmed; Kaval, Necati; Caldwell, Charles C; Gulbins, Erich; Edwards, Michael J; Gobble, Ryan M 2020. Doxycycline-Coated Silicone Breast Implants Reduce Acute Surgical-Site Infection and Inflammation. Plastic and reconstructive surgery, 146 5, 1029-1041

Hoehn, Richard S; Seitz, Aaron P; Singer, Kathleen E; Thompson, Jonathan R; Watkins, Brad M 2019. Enhanced Recovery Protocol for Laparoscopic Sleeve Gastrectomy: Are Narcotics Necessary? Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 23 8, 1541-1546

Seitz, Aaron P; Schumacher, Fabian; Baker, Jennifer; Soddemann, Matthias; Wilker, Barbara; Caldwell, Charles C; Gobble, Ryan M; Kamler, Markus; Becker, Katrin Anne; Beck, Sascha; Kleuser, Burkhard; Edwards, Michael J; Gulbins, Erich 2019. Sphingosine-coating of plastic surfaces prevents ventilator-associated pneumonia. Journal of molecular medicine (Berlin, Germany), 97 8, 1195-1211

Becker, Katrin Anne; Riethmüller, Joachim; Seitz, Aaron P; Gardner, Aaron; Boudreau, Ryan; Kamler, Markus; Kleuser, Burkhard; Schuchman, Edward; Caldwell, Charles C; Edwards, Michael J; Grassmé, Heike; Brodlie, Malcolm; Gulbins, Erich 2018. Sphingolipids as targets for inhalation treatment of cystic fibrosis. Advanced drug delivery reviews, ,

Chang, Alex L; Kim, Young; Seitz, Aaron P; Schuster, Rebecca M; Lentsch, Alex B; Pritts, Timothy A 2017. Erythrocyte-Derived Microparticles Activate Pulmonary Endothelial Cells in a Murine Model of Transfusion. Shock (Augusta, Ga.), 47 5, 632-637

Chang, Alex L; Kim, Young; Seitz, Aaron P; Schuster, Rebecca M; Pritts, Timothy A 2017. pH modulation ameliorates the red blood cell storage lesion in a murine model of transfusion. The Journal of surgical research, 212 , 54-59

Grassmé, Heike; Henry, Brian; Ziobro, Regan; Becker, Katrin Anne; Riethmüller, Joachim; Gardner, Aaron; Seitz, Aaron P; Steinmann, Joerg; Lang, Stephan; Ward, Christopher; Schuchman, Edward H; Caldwell, Charles C; Kamler, Markus; Edwards, Michael J; Brodlie, Malcolm; Gulbins, Erich 2017. ?1-Integrin Accumulates in Cystic Fibrosis Luminal Airway Epithelial Membranes and Decreases Sphingosine, Promoting Bacterial Infections. Cell host & microbe, 21 6, 707-718.e8

Kunz, Natalia; Xia, Brent T; Kalies, Kai-Uwe; Klinger, Matthias; Gemoll, Timo; Habermann, Jens K; Whitacre, Brynne E; Seitz, Aaron P; Kalies, Kathrin; Caldwell, Charles C 2017. Cell-Derived Nanoparticles are Endogenous Modulators of Sepsis With Therapeutic Potential. Shock (Augusta, Ga.), 48 3, 346-354

Rice, Teresa C; Pugh, Amanda M; Seitz, Aaron P; Gulbins, Erich; Nomellini, Vanessa; Caldwell, Charles C 2017. Sphingosine rescues aged mice from pulmonary pseudomonas infection. The Journal of surgical research, 219 , 354-359

Rice, Teresa C; Pugh, Amanda M; Xia, Brent T; Seitz, Aaron P; Whitacre, Brynne E; Gulbins, Erich; Caldwell, Charles C 2017. Bronchoalveolar Lavage Microvesicles Protect Burn-Injured Mice from Pulmonary Infection. Journal of the American College of Surgeons, 225 4, 538-547

Hoehn, Richard S; Seitz, Aaron P; Jernigan, Peter L; Gulbins, Erich; Edwards, Michael J 2016. Ischemia/Reperfusion Injury Alters Sphingolipid Metabolism in the Gut. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 39 4, 1262-70

Rice, Teresa C; Seitz, Aaron P; Edwards, Michael J; Gulbins, Erich; Caldwell, Charles C 2016. Frontline Science: Sphingosine rescues burn-injured mice from pulmonary Pseudomonas aeruginosa infection. Journal of leukocyte biology, 100 6, 1233-1237

Managò, Antonella; Becker, Katrin Anne; Carpinteiro, Alexander; Wilker, Barbara; Soddemann, Matthias; Seitz, Aaron P; Edwards, Michael J; Grassmé, Heike; Szabò, Ildiko; Gulbins, Erich 2015. Pseudomonas aeruginosa pyocyanin induces neutrophil death via mitochondrial reactive oxygen species and mitochondrial acid sphingomyelinase. Antioxidants & redox signaling, 22 13, 1097-110

Seitz, Aaron P; Grassmé, Heike; Edwards, Michael J; Pewzner-Jung, Yael; Gulbins, Erich 2015. Ceramide and sphingosine in pulmonary infections. Biological chemistry, 396 6-7, 611-20

Kasten, Kevin R; Prakash, Priya S; Unsinger, Jacqueline; Goetzman, Holly S; England, Lisa G; Cave, Cindy M; Seitz, Aaron P; Mazuski, Cristina N; Zhou, Tony T; Morre, Michel; Hotchkiss, Richard S; Hildeman, David A; Caldwell, Charles C 2010. Interleukin-7 (IL-7) treatment accelerates neutrophil recruitment through gamma delta T-cell IL-17 production in a murine model of sepsis. Infection and immunity, 78 11, 4714-22

Kasten, Kevin R; Tschöp, Johannes; Goetzman, Holly S; England, Lisa G; Dattilo, Jonathan R; Cave, Cindy M; Seitz, Aaron P; Hildeman, David A; Caldwell, Charles C 2010. T-cell activation differentially mediates the host response to sepsis. Shock (Augusta, Ga.), 34 4, 377-83

Becker K.; Caldwell C.; Edwards M.; Gulbins E.; Kamler M.; Koch A.; Li X.; Schuchman E.; Seitz A.; Steinmann J. 11-01-2017. Neutrophils Kill Reactive Oxygen Species-Resistant Pseudomonas aeruginosa by Sphingosine Cellular Physiology and Biochemistry, 43 4, 1603-1616

Becker K.;Li X.;Seitz A.;Steinmann J.;Koch A.;Schuchman E.;Kamler M.;Edwards M.;Caldwell C.;Gulbins E. 11-01-2017. Neutrophils Kill Reactive Oxygen Species-Resistant Pseudomonas aeruginosa by Sphingosine Cellular Physiology and Biochemistry, 43 4, 1603-1616

Becker K.; Boudreau R.; Caldwell C.; Couch C.; Edwards M.; Gulbins E.; Martin G.; Seitz A. 10-01-2017. Sphingosine's role in epithelial host defense: A natural antimicrobial and novel therapeutic Biochimie, 141 , 91-96

Martin G.;Boudreau R.;Couch C.;Becker K.;Edwards M.;Caldwell C.;Gulbins E.;Seitz A. 10-01-2017. Sphingosine's role in epithelial host defense: A natural antimicrobial and novel therapeutic Biochimie, 141 , 91-96

Hoehn R.; Seitz A.; Singer K.; Thompson J.; Watkins B. 08-15-2019. Enhanced Recovery Protocol for Laparoscopic Sleeve Gastrectomy: Are Narcotics Necessary? Journal of Gastrointestinal Surgery, 23 8, 1541-1546

Hoehn R.S.;Seitz A.P.;Singer K.E.;Thompson J.R.;Watkins B.M. 08-15-2019. Enhanced Recovery Protocol for Laparoscopic Sleeve Gastrectomy: Are Narcotics Necessary? Journal of Gastrointestinal Surgery, 23 8, 1541-1546

Becker K.; Edwards M.; Grassmé H.; Gulbins E.; Jernigan P.; Kahl B.; Keitsch S.; Lang S.; Sehl C.; Seitz A.; Tavakoli Tabazavareh S. 05-17-2016. Lack of Sphingosine Causes Susceptibility to Pulmonary Staphylococcus Aureus Infections in Cystic Fi Cellular Physiology and Biochemistry, 38 6, 2094-2102

Tavakoli Tabazavareh S.;Seitz A.;Jernigan P.;Sehl C.;Keitsch S.;Lang S.;Kahl B.;Edwards M.;Grassmé H.;Gulbins E.;Becker K. 05-17-2016. Lack of Sphingosine Causes Susceptibility to Pulmonary Staphylococcus Aureus Infections in Cystic Fi Cellular Physiology and Biochemistry, 38 6, 2094-2102

Becker K.; Caldwell C.; Edwards M.; Fahsel B.; Fraunholz M.; Grassmé H.; Gulbins E.; Keitsch S.; Kemper H.; Kohnen M.; Li C.; Mayeres J.; Sehl C.; Seitz A.; Soddemann M.; Wilker B. 01-01-2018. Staphylococcus aureus alpha-toxin disrupts endothelial-cell tight junctions via acid sphingomyelinas Infection and Immunity, 86 1,

Becker K.;Fahsel B.;Kemper H.;Mayeres J.;Li C.;Wilker B.;Keitsch S.;Soddemann M.;Sehl C.;Kohnen M.;Edwards M.;Grassmé H.;Caldwell C.;Seitz A.;Fraunholz M.;Gulbins E. 01-01-2018. Staphylococcus aureus alpha-toxin disrupts endothelial-cell tight junctions via acid sphingomyelinas Infection and Immunity, 86 1,

Becker K.; Beckmann N.; Carpinteiro A.; Edelmann B.; Gulbins E.; Helfrich I.; Hessler G.; Seitz A.; Soddemann M.; Wilker B. 01-01-2016. Role of Acid Sphingomyelinase-Induced Signaling in Melanoma Cells for Hematogenous Tumor Metastasis Cellular Physiology and Biochemistry, 38 1, 1-14

Edwards M.; Grassme H.; Gulbins E.; Japtok L.; Kleuser B.; Lammas D.; Li C.; Peng H.; Riehle A.; Seitz A.; Soddemann M.; Wilker B.; Zhang Y. 01-01-2016. Inhibition of neutral sphingomyelinase protects mice against systemic tuberculosis Frontiers in Bioscience - Elite, 8 2, 311-325

Carpinteiro A.;Beckmann N.;Seitz A.;Hessler G.;Wilker B.;Soddemann M.;Helfrich I.;Edelmann B.;Gulbins E.;Becker K. 01-01-2016. Role of Acid Sphingomyelinase-Induced Signaling in Melanoma Cells for Hematogenous Tumor Metastasis Cellular Physiology and Biochemistry, 38 1, 1-14

Li C.;Peng H.;Japtok L.;Seitz A.;Riehle A.;Wilker B.;Soddemann M.;Kleuser B.;Edwards M.;Lammas D.;Zhang Y.;Gulbins E.;Grassme H. 01-01-2016. Inhibition of neutral sphingomyelinase protects mice against systemic tuberculosis Frontiers in Bioscience - Elite, 8 2, 311-325

Baker, Jennifer E; Boudreau, Ryan M; Seitz, Aaron P; Caldwell, Charles C; Gulbins, Erich; Edwards, Michael J . Sphingolipids and Innate Immunity: A New Approach to Infection in the Post-Antibiotic Era? Surgical infections, 19 8, 792-803