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Photo of  William A. Knight IV, MD

William A. Knight IV, MD

Professor of Clinical

Director, EM MLP Program

Emergency Medicine | College of Medicine

Education/Credentials
  • Fellowship: University of Cincinnati (Neurovascular Emergencies & Neurocritical Care)
  • Residency: University of Cincinnati (Emergency Medicine)
  • Medical Degree: University of Cincinnati
  • Bachelor's Degree: University of Dayton (Biology and Psychology)
Board Certifications & Licenses

American Board of Emergency Medicine (Certification Date: 2008-11-13) - (Recertification Date: 2019-01-01)
United Council for Neurologic Subspecialties (Certification Date: 2010-12-31)

Specialties

Emergency Medicine
Neurocritical Care

Contact Information
Research Interests

neurocritical care, neurotrauma, stroke

Clinical Interests

Emergency Medicine

Brain Concussion

Severe Traumatic Brain Injury

Sports Related Injuries

Stroke, including Hemorrhagic Stroke and Ischemic Stroke

Subacute Combined Degeneration

Subdural Hematoma

Traumatic Injury

Peer Reviewed Publications

Smith, Matthew S; Bonomo, Jordan; Knight, William A; Prestigiacomo, Charles J; Richards, Christopher T; Ramser, Evan; Adeoye, Opeolu; Bertsch, Stuart; Shirani, Peyman; Vagal, Achala; Fichtenbaum, Carl J; Housholder, Anne; Khatri, Pooja; Kleindorfer, Dawn O; Broderick, Joseph P; Grossman, Aaron W 2020. Endovascular Therapy for Patients With Acute Ischemic Stroke During the COVID-19 Pandemic: A Proposed Algorithm. Stroke, 51 6, 1902-1909

Fuller, Brian M; Roberts, Brian W; Mohr, Nicholas M; Knight, William A; Adeoye, Opeolu; Pappal, Ryan D; Marshall, Stacy; Alunday, Robert; Dettmer, Matthew; Goyal, Munish; Gibson, Colin; Levine, Brian J; Gardner-Gray, Jayna M; Mosier, Jarrod; Dargin, James; Mackay, Fraser; Johnson, Nicholas J; Lokhandwala, Sharukh; Hough, Catherine L; Tonna, Joseph E; Tsolinas, Rachel; Lin, Frederick; Qasim, Zaffer A; Harvey, Carrie E; Bassin, Benjamin; Stephens, Robert J; Yan, Yan; Carpenter, Christopher R; Kollef, Marin H; Avidan, Michael S 2019. The ED-SED Study: A Multicenter, Prospective Cohort Study of Practice Patterns and Clinical Outcomes Associated With Emergency Department SEDation for Mechanically Ventilated Patients. Critical care medicine, 47 11, 1539-1548

Knight, William A; Hart, Kimberly W; Adeoye, Opeolu M; Bonomo, Jordan B; Keegan, Shaun P; Ficker, David M; Szaflarski, Jerzy P; Privitera, Michael D; Lindsell, Christopher J 2013. The incidence of seizures in patients undergoing therapeutic hypothermia after resuscitation from cardiac arrest. Epilepsy research, 106 3, 396-402

Pancioli, Arthur M; Adeoye, Opeolu; Schmit, Pamela A; Khoury, Jane; Levine, Steven R; Tomsick, Thomas A; Sucharew, Heidi; Brooks, Claudette E; Crocco, Todd J; Gutmann, Laurie; Hemmen, Thomas M; Kasner, Scott E; Kleindorfer, Dawn; Knight, William A; Martini, Sharyl; McKinney, James S; Meurer, William J; Meyer, Brett C; Schneider, Alexander; Scott, Phillip A; Starkman, Sidney; Warach, Steven; Broderick, Joseph P 2013. Combined approach to lysis utilizing eptifibatide and recombinant tissue plasminogen activator in acute ischemic stroke-enhanced regimen stroke trial. Stroke, 44 9, 2381-7

Zammit, Christopher; Knight, William A 2013. Severe traumatic brain injury in adults. Emergency medicine practice, 15 3, 1-28

McMullan, Jason T; Hinckley, William; Bentley, Jared; Davis, Todd; Fermann, Gregory J; Gunderman, Matthew; Hart, Kimberly Ward; Knight, William A; Lindsell, Christopher J; Miller, Chris; Shackleford, April; Gibler, W Brian 2012. Ground emergency medical services requests for helicopter transfer of ST-segment elevation myocardial infarction patients decrease medical contact to balloon times in rural and suburban settings. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 19 2, 153-60

McMullan, Jason T; Hinckley, William; Bentley, Jared; Davis, Todd; Fermann, Gregory J; Gunderman, Matthew; Hart, Kimberly Ward; Knight, William A; Lindsell, Christopher J; Shackleford, April; Gibler, W Brian 2011. Reperfusion is delayed beyond guideline recommendations in patients requiring interhospital helicopter transfer for treatment of ST-segment elevation myocardial infarction. Annals of emergency medicine, 57 3, 213-220.e1

McMullan, Jason T; Knight, William A; Clark, Joseph F; Beyette, Fred R; Pancioli, Arthur 2010. Time-critical neurological emergencies: the unfulfilled role for point-of-care testing. International journal of emergency medicine, 3 2, 127-31

Schwamm, Lee H; Holloway, Robert G; Amarenco, Pierre; Audebert, Heinrich J; Bakas, Tamilyn; Chumbler, Neale R; Handschu, Rene; Jauch, Edward C; Knight, William A; Levine, Steven R; Mayberg, Marc; Meyer, Brett C; Meyers, Philip M; Skalabrin, Elaine; Wechsler, Lawrence R 2009. A review of the evidence for the use of telemedicine within stroke systems of care: a scientific statement from the American Heart Association/American Stroke Association. Stroke, 40 7, 2616-34

Knight, W A; Livingston, R B; Gregory, E J; McGuire, W L 1977. Estrogen receptor as an independent prognostic factor for early recurrence in breast cancer. Cancer research, 37 12, 4669-71

Bohanske M.; Knight W.; McMullan J. 12-01-2015. MORNING EMERGENCIES. A guide to wake-up ischemic strokes Morning emergencies JEMS : a journal of emergency medical services, 40 12, 35-38

Palmer C.; McMullan J.; Knight W.; Gunderman M.; Hinckley W. 11-01-2011. Helicopter scene response for a STEMI patient transported directly to the cardiac catheterization la Air Medical Journal, 30 6, 289-292

McMullan J.T.; Jones E.; Barnhart B.; Denninghoff K.; Spaite D.; Zaleski E.; Silbergleit R.; Lowenstein D.; Barsan W.; Pancioli A.; Stevenson V.; Harney D.; Harsh D.; Pinkerton J.; Kade A.; Siewert N.; Pinawin A.; Ring C.; Brenne P.; Vonderschmidt K.; Durkalski V.; Palesch Y.; Dillon C.; Pauls K.; Wu Q.; Zhao W.; Conwit R.; Janis S.; Jett D.; Fureman B.; Welch R.D.; Mango L.; Mika V.H.; Atas J.; Dunne R.; Wheaton D.; Levy P.; Velilla M.A.; Sherwin R.; O'Neil B.; Groves A.; Rosenthal M.; Ewing I.; Waymeyer P.; Kay Vonderschmidt M.; Schwartz H.; Stettler B.; Knight W.; Adeoye O.; Cadena R.; Bonomo J.; Grise E.; Heitsch L.; Shaw G.; Gagai N.; Schmit P.; Stark S.; Doellman T.; Hemphill J.C.; Meeker M.; Rosborough K.; Sporer K.; Gelb A.; Smith W.; Ramanujam P.; Nakagawa K.; Moheet A.; Kamel H.; Naravetla B.; Mercer M.; Wong C.; Milling T.J.; Ottman M.; King B.; LaChance L.; Brockman J.; Didonato P.; Hinchey P.; Wright D.W.; Bitner M.D.; Beltran G.W.; Nevarez H.; Barnhard R.; McDougal A.G.; Linzer J.F.; Merck L.H.; Espinoza T.; Lewandowski C.A.; Vohra T.T.; Crouse P.L.; Baker A.E.; Creech D.R.; Russman A.N.; Miller J.B.; Nagarwala J.; Miller D.J.; Fowkes R.; Lundell A.M.; Quinn J.V.; Casal S. 07-01-2014. Degradation of benzodiazepines after 120 days of EMS deployment Prehospital Emergency Care, 18 3, 368-374

McMullan J.; Knight W.; Clark J.; Beyette F.; Pancioli A. 06-01-2010. Time-critical neurological emergencies: The unfulfilled role for point-of-care testing International Journal of Emergency Medicine, 3 2, 127-131

McMullan J.T.; Hinckley W.; Bentley J.; Davis T.; Fermann G.J.; Gunderman M.; Hart K.W.; Knight W.A.; Lindsell C.J.; Shackleford A.; Gibler W.B. 01-01-2011. Reperfusion is delayed beyond guideline recommendations in patients requiring interhospital helicopt Annals of Emergency Medicine, 57 3,

Adeoye, Opeolu; Knight, William A; Khoury, Jane; Schmit, Pamela A; Sucharew, Heidi; Broderick, Joseph P; Pancioli, Arthur M . A matched comparison of eptifibatide plus rt-PA versus rt-PA alone in acute ischemic stroke. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 23 5, e313-5

Knight, William A; Gunderman, Matthew; Hinckley, William R . Critical burn patient with an unknown neuromuscular disease: conclusion. Air medical journal, 27 4, 160-6

Knight, William A; Gunderman, Matthew; Hinckley, William R . Critical burn patient with an unknown neuromuscular disease. Air medical journal, 27 3, 114-5