Education/CredentialsFellowship: University of Cincinnati (Pulmonary and Critical Care Medicine)Residency: University of Cincinnati (Internal Medicine)Postdoctoral Research Fellowship: Johns Hopkins University (Immunobiology, Vascular Biology)Doctoral Degree: Virginia Commonwealth University (Molecular Biology and Genetics)Medical Student: Escuela de Medicina Board Certifications & LicensesAmerican Board of Internal Medicine (Certification Date: 2020-12-14)American Board of Internal Medicine (Pulmonary Disease) (Certification Date: 2022-11-29) LanguagesSpanish SpecialtiesCritical Care MedicineInternal Medicine Contact Information Medical Sciences Building Office 513-558-4831 Email gomezaje@ucmail.uc.edu Clinical Interests Critical Care MedicineLung Disease Peer Reviewed Publications Best, Myron G; Sol, Nik; In 't Veld, Sjors G J G; Vancura, Adrienne; Muller, Mirte; Niemeijer, Anna-Larissa N; Fejes, Aniko V; Tjon Kon Fat, Lee-Ann; Huis In 't Veld, Anna E; Leurs, Cyra; Le Large, Tessa Y; Meijer, Laura L; Kooi, Irsan E; Rustenburg, François; Schellen, Pepijn; Verschueren, Heleen; Post, Edward; Wedekind, Laurine E; Bracht, Jillian; Esenkbrink, Michelle; Wils, Leon; Favaro, Francesca; Schoonhoven, Jilian D; Tannous, Jihane; Meijers-Heijboer, Hanne; Kazemier, Geert; Giovannetti, Elisa; Reijneveld, Jaap C; Idema, Sander; Killestein, Joep; Heger, Michal; de Jager, Saskia C; Urbanus, Rolf T; Hoefer, Imo E; Pasterkamp, Gerard; Mannhalter, Christine; Gomez-Arroyo, Jose; Bogaard, Harm-Jan; Noske, David P; Vandertop, W Peter; van den Broek, Daan; Ylstra, Bauke; Nilsson, R Jonas A; Wesseling, Pieter; Karachaliou, Niki; Rosell, Rafael; Lee-Lewandrowski, Elizabeth; Lewandrowski, Kent B; Tannous, Bakhos A; de Langen, Adrianus J; Smit, Egbert F; van den Heuvel, Michel M; Wurdinger, Thomas 2017. Swarm Intelligence-Enhanced Detection of Non-Small-Cell Lung Cancer Using Tumor-Educated Platelets. Cancer cell, 32 2, 238-252.e9Mizuno, Shiro; Ishizaki, Takeshi; Kadowaki, Maiko; Akai, Masaya; Shiozaki, Kohei; Iguchi, Masaharu; Oikawa, Taku; Nakagawa, Ken; Osanai, Kazuhiro; Toga, Hirohisa; Gomez-Arroyo, Jose; Kraskauskas, Donatas; Cool, Carlyne D; Bogaard, Herman J; Voelkel, Norbert F 2017. p53 Signaling Pathway Polymorphisms Associated With Emphysematous Changes in Patients With COPD. Chest, 152 1, 58-69Gomez-Arroyo, Jose; Abbate, Antonio; Voelkel, Norbert F 2016. Pulmonary arterial hypertension and the Enigma code of smouldering inflammation. The European respiratory journal, 48 2, 305-7Gomez-Arroyo, Jose; Sakagami, Masahiro; Syed, Aamer A; Farkas, Laszlo; Van Tassell, Benjamin; Kraskauskas, Donatas; Mizuno, Shiro; Abbate, Antonio; Bogaard, Harm J; Byron, Peter R; Voelkel, Norbert F 2015. Iloprost reverses established fibrosis in experimental right ventricular failure. The European respiratory journal, 45 2, 449-62Sandoval, Julio; Gomez-Arroyo, Jose; Gaspar, Jorge; Pulido-Zamudio, Tomas 2015. Interventional and surgical therapeutic strategies for pulmonary arterial hypertension: Beyond palliative treatments. Journal of cardiology, 66 4, 304-14Voelkel, Norbert F; Bogaard, Harm Jan; Gomez-Arroyo, Jose 2015. The need to recognize the pulmonary circulation and the right ventricle as an integrated functional unit: facts and hypotheses (2013 Grover Conference series). Pulmonary circulation, 5 1, 81-9De Raaf, Michiel Alexander; Hussaini, Aysar Al; Gomez-Arroyo, Jose; Kraskaukas, Donatas; Farkas, Daniela; Happé, Chris; Voelkel, Norbert F; Bogaard, Harm Jan 2014. Histone deacetylase inhibition with trichostatin A does not reverse severe angioproliferative pulmonary hypertension in rats (2013 Grover Conference series). Pulmonary circulation, 4 2, 237-43de Raaf, Michiel Alexander; Schalij, Ingrid; Gomez-Arroyo, Jose; Rol, Nina; Happé, Chris; de Man, Frances S; Vonk-Noordegraaf, Anton; Westerhof, Nico; Voelkel, Norbert F; Bogaard, Harm Jan 2014. SuHx rat model: partly reversible pulmonary hypertension and progressive intima obstruction. The European respiratory journal, 44 1, 160-8Gomez-Arroyo, Jose; Sandoval, Julio; Simon, Marc A; Dominguez-Cano, Erick; Voelkel, Norbert F; Bogaard, Harm J 2014. Treatment for pulmonary arterial hypertension-associated right ventricular dysfunction. Annals of the American Thoracic Society, 11 7, 1101-15Gomez-Arroyo, Jose; Santos-Martinez, Luis E; Aranda, Alberto; Pulido, Tomas; Beltran, Miguel; Muñoz-Castellanos, Luis; Dominguez-Cano, Erick; Sonnino, Chiara; Voelkel, Norbert F; Sandoval, Julio 2014. Differences in right ventricular remodeling secondary to pressure overload in patients with pulmonary hypertension. American journal of respiratory and critical care medicine, 189 5, 603-6Voelkel, Norbert F; Gomez-Arroyo, Jose 2014. The role of vascular endothelial growth factor in pulmonary arterial hypertension. The angiogenesis paradox. American journal of respiratory cell and molecular biology, 51 4, 474-84Al Husseini, Aysar; Bagnato, Gianluca; Farkas, Laszlo; Gomez-Arroyo, Jose; Farkas, Daniela; Mizuno, Shiro; Kraskauskas, Donatas; Abbate, Antonio; Van Tassel, Benjamin; Voelkel, Norbert F; Bogaard, Harm Jan 2013. Thyroid hormone is highly permissive in angioproliferative pulmonary hypertension in rats. The European respiratory journal, 41 1, 104-14Drake, Jennifer I; Gomez-Arroyo, Jose; Dumur, Catherine I; Kraskauskas, Donatas; Natarajan, Ramesh; Bogaard, Harm J; Fawcett, Paul; Voelkel, Norbert F 2013. Chronic carvedilol treatment partially reverses the right ventricular failure transcriptional profile in experimental pulmonary hypertension. Physiological genomics, 45 12, 449-61Gomez-Arroyo, Jose; Mizuno, Shiro; Szczepanek, Karol; Van Tassell, Benjamin; Natarajan, Ramesh; dos Remedios, Cristobal G; Drake, Jennifer I; Farkas, Laszlo; Kraskauskas, Donatas; Wijesinghe, Dayanjan S; Chalfant, Charles E; Bigbee, John; Abbate, Antonio; Lesnefsky, Edward J; Bogaard, Harm J; Voelkel, Norbert F 2013. Metabolic gene remodeling and mitochondrial dysfunction in failing right ventricular hypertrophy secondary to pulmonary arterial hypertension. Circulation. Heart failure, 6 1, 136-44Voelkel, Norbert F; Bogaard, Harm J; Al Husseini, Aysar; Farkas, Laszlo; Gomez-Arroyo, Jose; Natarajan, Ramesh 2013. Antioxidants for the treatment of patients with severe angioproliferative pulmonary hypertension? Antioxidants & redox signaling, 18 14, 1810-7Voelkel, Norbert F; Gomez-Arroyo, Jose; Abbate, Antonio; Bogaard, Harm J 2013. Mechanisms of right heart failure-A work in progress and a plea for failure prevention. Pulmonary circulation, 3 1, 137-43Gomez-Arroyo, Jose G; Farkas, Laszlo; Alhussaini, Aysar A; Farkas, Daniela; Kraskauskas, Donatas; Voelkel, Norbert F; Bogaard, Harm J 2012. The monocrotaline model of pulmonary hypertension in perspective. American journal of physiology. Lung cellular and molecular physiology, 302 4, L363-9Gomez-Arroyo, Jose; Saleem, Sheinei J; Mizuno, Shiro; Syed, Aamer A; Bogaard, Harm J; Abbate, Antonio; Taraseviciene-Stewart, Laimute; Sung, Yon; Kraskauskas, Donatas; Farkas, Daniela; Conrad, Daniel H; Nicolls, Mark R; Voelkel, Norbert F 2012. A brief overview of mouse models of pulmonary arterial hypertension: problems and prospects. American journal of physiology. Lung cellular and molecular physiology, 302 10, L977-91Gomez-Arroyo, José; Voelkel, Norbert F; Bogaard, Harm J; Taraseviciene-Stewart, Laima 2012. Usefulness of a mouse model of reversible pulmonary arterial hypertension: be cautious, choose carefully. American journal of respiratory and critical care medicine, 185 12, 1326; author reply 1Mizuno, Shiro; Bogaard, Harm J; Gomez-Arroyo, Jose; Alhussaini, Aysar; Kraskauskas, Donatas; Cool, Carlyne D; Voelkel, Norbert F 2012. MicroRNA-199a-5p is associated with hypoxia-inducible factor-1? expression in lungs from patients with COPD. Chest, 142 3, 663-672Mizuno, Shiro; Farkas, Laszlo; Al Husseini, Aysar; Farkas, Daniela; Gomez-Arroyo, Jose; Kraskauskas, Donatas; Nicolls, Mark R; Cool, Carlyne D; Bogaard, Herman J; Voelkel, Norbert F 2012. Severe pulmonary arterial hypertension induced by SU5416 and ovalbumin immunization. American journal of respiratory cell and molecular biology, 47 5, 679-87Mizuno, Shiro; Yasuo, Masanori; Bogaard, Harm J; Kraskauskas, Donatas; Alhussaini, Aysar; Gomez-Arroyo, Jose; Farkas, Daniela; Farkas, Laszlo; Voelkel, Norbert F 2012. Copper deficiency induced emphysema is associated with focal adhesion kinase inactivation. PloS one, 7 1, e30678Nicolls, Mark R; Mizuno, Shiro; Taraseviciene-Stewart, Laima; Farkas, Laszlo; Drake, Jennnifer I; Al Husseini, Aysar; Gomez-Arroyo, Jose G; Voelkel, Norbert F; Bogaard, Herman J 2012. New models of pulmonary hypertension based on VEGF receptor blockade-induced endothelial cell apoptosis. Pulmonary circulation, 2 4, 434-42Van Tassell, Benjamin W; Bhardwaj, Hem L; Grizzard, John D; Kontos, Michael C; Bogaard, Herman; Gomez-Arroyo, Jose; Toldo, Stefano; Mezzaroma, Eleonora; Voelkel, Norbert F; Abbate, Antonio 2012. Right ventricular systolic dysfunction in patients with reperfused ST-segment elevation acute myocardial infarction. International journal of cardiology, 155 2, 314-6Voelkel, Norbert F; Gomez-Arroyo, Jose; Abbate, Antonio; Bogaard, Harm J; Nicolls, Mark R 2012. Pathobiology of pulmonary arterial hypertension and right ventricular failure. The European respiratory journal, 40 6, 1555-65Mizuno, Shiro; Bogaard, Herman J; Kraskauskas, Donatas; Alhussaini, Aysar; Gomez-Arroyo, Jose; Voelkel, Norbert F; Ishizaki, Takeshi 2011. p53 Gene deficiency promotes hypoxia-induced pulmonary hypertension and vascular remodeling in mice. American journal of physiology. Lung cellular and molecular physiology, 300 5, L753-61Voelkel, N F; Gomez-Arroyo, J 2011. The harmonics of rodent pulmonary hypertension models. International journal of clinical practice. Supplement, 172, 1-2Bogaard, Harm J; Al Husseini, Aysar; Farkas, Laszlo; Farkas, Daniela; Gomez-Arroyo, Jose; Abbate, Antonio; Voelkel, Norbert F . Severe pulmonary hypertension: The role of metabolic and endocrine disorders. Pulmonary circulation, 2 2, 148-54Voelkel, Norbert F; Gomez-Arroyo, Jose; Mizuno, Shiro . COPD/emphysema: The vascular story. Pulmonary circulation, 1 3, 320-6
Peer Reviewed Publications Best, Myron G; Sol, Nik; In 't Veld, Sjors G J G; Vancura, Adrienne; Muller, Mirte; Niemeijer, Anna-Larissa N; Fejes, Aniko V; Tjon Kon Fat, Lee-Ann; Huis In 't Veld, Anna E; Leurs, Cyra; Le Large, Tessa Y; Meijer, Laura L; Kooi, Irsan E; Rustenburg, François; Schellen, Pepijn; Verschueren, Heleen; Post, Edward; Wedekind, Laurine E; Bracht, Jillian; Esenkbrink, Michelle; Wils, Leon; Favaro, Francesca; Schoonhoven, Jilian D; Tannous, Jihane; Meijers-Heijboer, Hanne; Kazemier, Geert; Giovannetti, Elisa; Reijneveld, Jaap C; Idema, Sander; Killestein, Joep; Heger, Michal; de Jager, Saskia C; Urbanus, Rolf T; Hoefer, Imo E; Pasterkamp, Gerard; Mannhalter, Christine; Gomez-Arroyo, Jose; Bogaard, Harm-Jan; Noske, David P; Vandertop, W Peter; van den Broek, Daan; Ylstra, Bauke; Nilsson, R Jonas A; Wesseling, Pieter; Karachaliou, Niki; Rosell, Rafael; Lee-Lewandrowski, Elizabeth; Lewandrowski, Kent B; Tannous, Bakhos A; de Langen, Adrianus J; Smit, Egbert F; van den Heuvel, Michel M; Wurdinger, Thomas 2017. Swarm Intelligence-Enhanced Detection of Non-Small-Cell Lung Cancer Using Tumor-Educated Platelets. Cancer cell, 32 2, 238-252.e9Mizuno, Shiro; Ishizaki, Takeshi; Kadowaki, Maiko; Akai, Masaya; Shiozaki, Kohei; Iguchi, Masaharu; Oikawa, Taku; Nakagawa, Ken; Osanai, Kazuhiro; Toga, Hirohisa; Gomez-Arroyo, Jose; Kraskauskas, Donatas; Cool, Carlyne D; Bogaard, Herman J; Voelkel, Norbert F 2017. p53 Signaling Pathway Polymorphisms Associated With Emphysematous Changes in Patients With COPD. Chest, 152 1, 58-69Gomez-Arroyo, Jose; Abbate, Antonio; Voelkel, Norbert F 2016. Pulmonary arterial hypertension and the Enigma code of smouldering inflammation. The European respiratory journal, 48 2, 305-7Gomez-Arroyo, Jose; Sakagami, Masahiro; Syed, Aamer A; Farkas, Laszlo; Van Tassell, Benjamin; Kraskauskas, Donatas; Mizuno, Shiro; Abbate, Antonio; Bogaard, Harm J; Byron, Peter R; Voelkel, Norbert F 2015. Iloprost reverses established fibrosis in experimental right ventricular failure. The European respiratory journal, 45 2, 449-62Sandoval, Julio; Gomez-Arroyo, Jose; Gaspar, Jorge; Pulido-Zamudio, Tomas 2015. Interventional and surgical therapeutic strategies for pulmonary arterial hypertension: Beyond palliative treatments. Journal of cardiology, 66 4, 304-14Voelkel, Norbert F; Bogaard, Harm Jan; Gomez-Arroyo, Jose 2015. The need to recognize the pulmonary circulation and the right ventricle as an integrated functional unit: facts and hypotheses (2013 Grover Conference series). Pulmonary circulation, 5 1, 81-9De Raaf, Michiel Alexander; Hussaini, Aysar Al; Gomez-Arroyo, Jose; Kraskaukas, Donatas; Farkas, Daniela; Happé, Chris; Voelkel, Norbert F; Bogaard, Harm Jan 2014. Histone deacetylase inhibition with trichostatin A does not reverse severe angioproliferative pulmonary hypertension in rats (2013 Grover Conference series). Pulmonary circulation, 4 2, 237-43de Raaf, Michiel Alexander; Schalij, Ingrid; Gomez-Arroyo, Jose; Rol, Nina; Happé, Chris; de Man, Frances S; Vonk-Noordegraaf, Anton; Westerhof, Nico; Voelkel, Norbert F; Bogaard, Harm Jan 2014. SuHx rat model: partly reversible pulmonary hypertension and progressive intima obstruction. The European respiratory journal, 44 1, 160-8Gomez-Arroyo, Jose; Sandoval, Julio; Simon, Marc A; Dominguez-Cano, Erick; Voelkel, Norbert F; Bogaard, Harm J 2014. Treatment for pulmonary arterial hypertension-associated right ventricular dysfunction. Annals of the American Thoracic Society, 11 7, 1101-15Gomez-Arroyo, Jose; Santos-Martinez, Luis E; Aranda, Alberto; Pulido, Tomas; Beltran, Miguel; Muñoz-Castellanos, Luis; Dominguez-Cano, Erick; Sonnino, Chiara; Voelkel, Norbert F; Sandoval, Julio 2014. Differences in right ventricular remodeling secondary to pressure overload in patients with pulmonary hypertension. American journal of respiratory and critical care medicine, 189 5, 603-6Voelkel, Norbert F; Gomez-Arroyo, Jose 2014. The role of vascular endothelial growth factor in pulmonary arterial hypertension. The angiogenesis paradox. American journal of respiratory cell and molecular biology, 51 4, 474-84Al Husseini, Aysar; Bagnato, Gianluca; Farkas, Laszlo; Gomez-Arroyo, Jose; Farkas, Daniela; Mizuno, Shiro; Kraskauskas, Donatas; Abbate, Antonio; Van Tassel, Benjamin; Voelkel, Norbert F; Bogaard, Harm Jan 2013. Thyroid hormone is highly permissive in angioproliferative pulmonary hypertension in rats. The European respiratory journal, 41 1, 104-14Drake, Jennifer I; Gomez-Arroyo, Jose; Dumur, Catherine I; Kraskauskas, Donatas; Natarajan, Ramesh; Bogaard, Harm J; Fawcett, Paul; Voelkel, Norbert F 2013. Chronic carvedilol treatment partially reverses the right ventricular failure transcriptional profile in experimental pulmonary hypertension. Physiological genomics, 45 12, 449-61Gomez-Arroyo, Jose; Mizuno, Shiro; Szczepanek, Karol; Van Tassell, Benjamin; Natarajan, Ramesh; dos Remedios, Cristobal G; Drake, Jennifer I; Farkas, Laszlo; Kraskauskas, Donatas; Wijesinghe, Dayanjan S; Chalfant, Charles E; Bigbee, John; Abbate, Antonio; Lesnefsky, Edward J; Bogaard, Harm J; Voelkel, Norbert F 2013. Metabolic gene remodeling and mitochondrial dysfunction in failing right ventricular hypertrophy secondary to pulmonary arterial hypertension. Circulation. Heart failure, 6 1, 136-44Voelkel, Norbert F; Bogaard, Harm J; Al Husseini, Aysar; Farkas, Laszlo; Gomez-Arroyo, Jose; Natarajan, Ramesh 2013. Antioxidants for the treatment of patients with severe angioproliferative pulmonary hypertension? Antioxidants & redox signaling, 18 14, 1810-7Voelkel, Norbert F; Gomez-Arroyo, Jose; Abbate, Antonio; Bogaard, Harm J 2013. Mechanisms of right heart failure-A work in progress and a plea for failure prevention. Pulmonary circulation, 3 1, 137-43Gomez-Arroyo, Jose G; Farkas, Laszlo; Alhussaini, Aysar A; Farkas, Daniela; Kraskauskas, Donatas; Voelkel, Norbert F; Bogaard, Harm J 2012. The monocrotaline model of pulmonary hypertension in perspective. American journal of physiology. Lung cellular and molecular physiology, 302 4, L363-9Gomez-Arroyo, Jose; Saleem, Sheinei J; Mizuno, Shiro; Syed, Aamer A; Bogaard, Harm J; Abbate, Antonio; Taraseviciene-Stewart, Laimute; Sung, Yon; Kraskauskas, Donatas; Farkas, Daniela; Conrad, Daniel H; Nicolls, Mark R; Voelkel, Norbert F 2012. A brief overview of mouse models of pulmonary arterial hypertension: problems and prospects. American journal of physiology. Lung cellular and molecular physiology, 302 10, L977-91Gomez-Arroyo, José; Voelkel, Norbert F; Bogaard, Harm J; Taraseviciene-Stewart, Laima 2012. Usefulness of a mouse model of reversible pulmonary arterial hypertension: be cautious, choose carefully. American journal of respiratory and critical care medicine, 185 12, 1326; author reply 1Mizuno, Shiro; Bogaard, Harm J; Gomez-Arroyo, Jose; Alhussaini, Aysar; Kraskauskas, Donatas; Cool, Carlyne D; Voelkel, Norbert F 2012. MicroRNA-199a-5p is associated with hypoxia-inducible factor-1? expression in lungs from patients with COPD. Chest, 142 3, 663-672Mizuno, Shiro; Farkas, Laszlo; Al Husseini, Aysar; Farkas, Daniela; Gomez-Arroyo, Jose; Kraskauskas, Donatas; Nicolls, Mark R; Cool, Carlyne D; Bogaard, Herman J; Voelkel, Norbert F 2012. Severe pulmonary arterial hypertension induced by SU5416 and ovalbumin immunization. American journal of respiratory cell and molecular biology, 47 5, 679-87Mizuno, Shiro; Yasuo, Masanori; Bogaard, Harm J; Kraskauskas, Donatas; Alhussaini, Aysar; Gomez-Arroyo, Jose; Farkas, Daniela; Farkas, Laszlo; Voelkel, Norbert F 2012. Copper deficiency induced emphysema is associated with focal adhesion kinase inactivation. PloS one, 7 1, e30678Nicolls, Mark R; Mizuno, Shiro; Taraseviciene-Stewart, Laima; Farkas, Laszlo; Drake, Jennnifer I; Al Husseini, Aysar; Gomez-Arroyo, Jose G; Voelkel, Norbert F; Bogaard, Herman J 2012. New models of pulmonary hypertension based on VEGF receptor blockade-induced endothelial cell apoptosis. Pulmonary circulation, 2 4, 434-42Van Tassell, Benjamin W; Bhardwaj, Hem L; Grizzard, John D; Kontos, Michael C; Bogaard, Herman; Gomez-Arroyo, Jose; Toldo, Stefano; Mezzaroma, Eleonora; Voelkel, Norbert F; Abbate, Antonio 2012. Right ventricular systolic dysfunction in patients with reperfused ST-segment elevation acute myocardial infarction. International journal of cardiology, 155 2, 314-6Voelkel, Norbert F; Gomez-Arroyo, Jose; Abbate, Antonio; Bogaard, Harm J; Nicolls, Mark R 2012. Pathobiology of pulmonary arterial hypertension and right ventricular failure. The European respiratory journal, 40 6, 1555-65Mizuno, Shiro; Bogaard, Herman J; Kraskauskas, Donatas; Alhussaini, Aysar; Gomez-Arroyo, Jose; Voelkel, Norbert F; Ishizaki, Takeshi 2011. p53 Gene deficiency promotes hypoxia-induced pulmonary hypertension and vascular remodeling in mice. American journal of physiology. Lung cellular and molecular physiology, 300 5, L753-61Voelkel, N F; Gomez-Arroyo, J 2011. The harmonics of rodent pulmonary hypertension models. International journal of clinical practice. Supplement, 172, 1-2Bogaard, Harm J; Al Husseini, Aysar; Farkas, Laszlo; Farkas, Daniela; Gomez-Arroyo, Jose; Abbate, Antonio; Voelkel, Norbert F . Severe pulmonary hypertension: The role of metabolic and endocrine disorders. Pulmonary circulation, 2 2, 148-54Voelkel, Norbert F; Gomez-Arroyo, Jose; Mizuno, Shiro . COPD/emphysema: The vascular story. Pulmonary circulation, 1 3, 320-6
Best, Myron G; Sol, Nik; In 't Veld, Sjors G J G; Vancura, Adrienne; Muller, Mirte; Niemeijer, Anna-Larissa N; Fejes, Aniko V; Tjon Kon Fat, Lee-Ann; Huis In 't Veld, Anna E; Leurs, Cyra; Le Large, Tessa Y; Meijer, Laura L; Kooi, Irsan E; Rustenburg, François; Schellen, Pepijn; Verschueren, Heleen; Post, Edward; Wedekind, Laurine E; Bracht, Jillian; Esenkbrink, Michelle; Wils, Leon; Favaro, Francesca; Schoonhoven, Jilian D; Tannous, Jihane; Meijers-Heijboer, Hanne; Kazemier, Geert; Giovannetti, Elisa; Reijneveld, Jaap C; Idema, Sander; Killestein, Joep; Heger, Michal; de Jager, Saskia C; Urbanus, Rolf T; Hoefer, Imo E; Pasterkamp, Gerard; Mannhalter, Christine; Gomez-Arroyo, Jose; Bogaard, Harm-Jan; Noske, David P; Vandertop, W Peter; van den Broek, Daan; Ylstra, Bauke; Nilsson, R Jonas A; Wesseling, Pieter; Karachaliou, Niki; Rosell, Rafael; Lee-Lewandrowski, Elizabeth; Lewandrowski, Kent B; Tannous, Bakhos A; de Langen, Adrianus J; Smit, Egbert F; van den Heuvel, Michel M; Wurdinger, Thomas 2017. Swarm Intelligence-Enhanced Detection of Non-Small-Cell Lung Cancer Using Tumor-Educated Platelets. Cancer cell, 32 2, 238-252.e9Mizuno, Shiro; Ishizaki, Takeshi; Kadowaki, Maiko; Akai, Masaya; Shiozaki, Kohei; Iguchi, Masaharu; Oikawa, Taku; Nakagawa, Ken; Osanai, Kazuhiro; Toga, Hirohisa; Gomez-Arroyo, Jose; Kraskauskas, Donatas; Cool, Carlyne D; Bogaard, Herman J; Voelkel, Norbert F 2017. p53 Signaling Pathway Polymorphisms Associated With Emphysematous Changes in Patients With COPD. Chest, 152 1, 58-69Gomez-Arroyo, Jose; Abbate, Antonio; Voelkel, Norbert F 2016. Pulmonary arterial hypertension and the Enigma code of smouldering inflammation. The European respiratory journal, 48 2, 305-7Gomez-Arroyo, Jose; Sakagami, Masahiro; Syed, Aamer A; Farkas, Laszlo; Van Tassell, Benjamin; Kraskauskas, Donatas; Mizuno, Shiro; Abbate, Antonio; Bogaard, Harm J; Byron, Peter R; Voelkel, Norbert F 2015. Iloprost reverses established fibrosis in experimental right ventricular failure. The European respiratory journal, 45 2, 449-62Sandoval, Julio; Gomez-Arroyo, Jose; Gaspar, Jorge; Pulido-Zamudio, Tomas 2015. Interventional and surgical therapeutic strategies for pulmonary arterial hypertension: Beyond palliative treatments. Journal of cardiology, 66 4, 304-14Voelkel, Norbert F; Bogaard, Harm Jan; Gomez-Arroyo, Jose 2015. The need to recognize the pulmonary circulation and the right ventricle as an integrated functional unit: facts and hypotheses (2013 Grover Conference series). Pulmonary circulation, 5 1, 81-9De Raaf, Michiel Alexander; Hussaini, Aysar Al; Gomez-Arroyo, Jose; Kraskaukas, Donatas; Farkas, Daniela; Happé, Chris; Voelkel, Norbert F; Bogaard, Harm Jan 2014. Histone deacetylase inhibition with trichostatin A does not reverse severe angioproliferative pulmonary hypertension in rats (2013 Grover Conference series). Pulmonary circulation, 4 2, 237-43de Raaf, Michiel Alexander; Schalij, Ingrid; Gomez-Arroyo, Jose; Rol, Nina; Happé, Chris; de Man, Frances S; Vonk-Noordegraaf, Anton; Westerhof, Nico; Voelkel, Norbert F; Bogaard, Harm Jan 2014. SuHx rat model: partly reversible pulmonary hypertension and progressive intima obstruction. The European respiratory journal, 44 1, 160-8Gomez-Arroyo, Jose; Sandoval, Julio; Simon, Marc A; Dominguez-Cano, Erick; Voelkel, Norbert F; Bogaard, Harm J 2014. Treatment for pulmonary arterial hypertension-associated right ventricular dysfunction. Annals of the American Thoracic Society, 11 7, 1101-15Gomez-Arroyo, Jose; Santos-Martinez, Luis E; Aranda, Alberto; Pulido, Tomas; Beltran, Miguel; Muñoz-Castellanos, Luis; Dominguez-Cano, Erick; Sonnino, Chiara; Voelkel, Norbert F; Sandoval, Julio 2014. Differences in right ventricular remodeling secondary to pressure overload in patients with pulmonary hypertension. American journal of respiratory and critical care medicine, 189 5, 603-6Voelkel, Norbert F; Gomez-Arroyo, Jose 2014. The role of vascular endothelial growth factor in pulmonary arterial hypertension. The angiogenesis paradox. American journal of respiratory cell and molecular biology, 51 4, 474-84Al Husseini, Aysar; Bagnato, Gianluca; Farkas, Laszlo; Gomez-Arroyo, Jose; Farkas, Daniela; Mizuno, Shiro; Kraskauskas, Donatas; Abbate, Antonio; Van Tassel, Benjamin; Voelkel, Norbert F; Bogaard, Harm Jan 2013. Thyroid hormone is highly permissive in angioproliferative pulmonary hypertension in rats. The European respiratory journal, 41 1, 104-14Drake, Jennifer I; Gomez-Arroyo, Jose; Dumur, Catherine I; Kraskauskas, Donatas; Natarajan, Ramesh; Bogaard, Harm J; Fawcett, Paul; Voelkel, Norbert F 2013. Chronic carvedilol treatment partially reverses the right ventricular failure transcriptional profile in experimental pulmonary hypertension. Physiological genomics, 45 12, 449-61Gomez-Arroyo, Jose; Mizuno, Shiro; Szczepanek, Karol; Van Tassell, Benjamin; Natarajan, Ramesh; dos Remedios, Cristobal G; Drake, Jennifer I; Farkas, Laszlo; Kraskauskas, Donatas; Wijesinghe, Dayanjan S; Chalfant, Charles E; Bigbee, John; Abbate, Antonio; Lesnefsky, Edward J; Bogaard, Harm J; Voelkel, Norbert F 2013. Metabolic gene remodeling and mitochondrial dysfunction in failing right ventricular hypertrophy secondary to pulmonary arterial hypertension. Circulation. Heart failure, 6 1, 136-44Voelkel, Norbert F; Bogaard, Harm J; Al Husseini, Aysar; Farkas, Laszlo; Gomez-Arroyo, Jose; Natarajan, Ramesh 2013. Antioxidants for the treatment of patients with severe angioproliferative pulmonary hypertension? Antioxidants & redox signaling, 18 14, 1810-7Voelkel, Norbert F; Gomez-Arroyo, Jose; Abbate, Antonio; Bogaard, Harm J 2013. Mechanisms of right heart failure-A work in progress and a plea for failure prevention. Pulmonary circulation, 3 1, 137-43Gomez-Arroyo, Jose G; Farkas, Laszlo; Alhussaini, Aysar A; Farkas, Daniela; Kraskauskas, Donatas; Voelkel, Norbert F; Bogaard, Harm J 2012. The monocrotaline model of pulmonary hypertension in perspective. American journal of physiology. Lung cellular and molecular physiology, 302 4, L363-9Gomez-Arroyo, Jose; Saleem, Sheinei J; Mizuno, Shiro; Syed, Aamer A; Bogaard, Harm J; Abbate, Antonio; Taraseviciene-Stewart, Laimute; Sung, Yon; Kraskauskas, Donatas; Farkas, Daniela; Conrad, Daniel H; Nicolls, Mark R; Voelkel, Norbert F 2012. A brief overview of mouse models of pulmonary arterial hypertension: problems and prospects. American journal of physiology. Lung cellular and molecular physiology, 302 10, L977-91Gomez-Arroyo, José; Voelkel, Norbert F; Bogaard, Harm J; Taraseviciene-Stewart, Laima 2012. Usefulness of a mouse model of reversible pulmonary arterial hypertension: be cautious, choose carefully. American journal of respiratory and critical care medicine, 185 12, 1326; author reply 1Mizuno, Shiro; Bogaard, Harm J; Gomez-Arroyo, Jose; Alhussaini, Aysar; Kraskauskas, Donatas; Cool, Carlyne D; Voelkel, Norbert F 2012. MicroRNA-199a-5p is associated with hypoxia-inducible factor-1? expression in lungs from patients with COPD. Chest, 142 3, 663-672Mizuno, Shiro; Farkas, Laszlo; Al Husseini, Aysar; Farkas, Daniela; Gomez-Arroyo, Jose; Kraskauskas, Donatas; Nicolls, Mark R; Cool, Carlyne D; Bogaard, Herman J; Voelkel, Norbert F 2012. Severe pulmonary arterial hypertension induced by SU5416 and ovalbumin immunization. American journal of respiratory cell and molecular biology, 47 5, 679-87Mizuno, Shiro; Yasuo, Masanori; Bogaard, Harm J; Kraskauskas, Donatas; Alhussaini, Aysar; Gomez-Arroyo, Jose; Farkas, Daniela; Farkas, Laszlo; Voelkel, Norbert F 2012. Copper deficiency induced emphysema is associated with focal adhesion kinase inactivation. PloS one, 7 1, e30678Nicolls, Mark R; Mizuno, Shiro; Taraseviciene-Stewart, Laima; Farkas, Laszlo; Drake, Jennnifer I; Al Husseini, Aysar; Gomez-Arroyo, Jose G; Voelkel, Norbert F; Bogaard, Herman J 2012. New models of pulmonary hypertension based on VEGF receptor blockade-induced endothelial cell apoptosis. Pulmonary circulation, 2 4, 434-42Van Tassell, Benjamin W; Bhardwaj, Hem L; Grizzard, John D; Kontos, Michael C; Bogaard, Herman; Gomez-Arroyo, Jose; Toldo, Stefano; Mezzaroma, Eleonora; Voelkel, Norbert F; Abbate, Antonio 2012. Right ventricular systolic dysfunction in patients with reperfused ST-segment elevation acute myocardial infarction. International journal of cardiology, 155 2, 314-6Voelkel, Norbert F; Gomez-Arroyo, Jose; Abbate, Antonio; Bogaard, Harm J; Nicolls, Mark R 2012. Pathobiology of pulmonary arterial hypertension and right ventricular failure. The European respiratory journal, 40 6, 1555-65Mizuno, Shiro; Bogaard, Herman J; Kraskauskas, Donatas; Alhussaini, Aysar; Gomez-Arroyo, Jose; Voelkel, Norbert F; Ishizaki, Takeshi 2011. p53 Gene deficiency promotes hypoxia-induced pulmonary hypertension and vascular remodeling in mice. American journal of physiology. Lung cellular and molecular physiology, 300 5, L753-61Voelkel, N F; Gomez-Arroyo, J 2011. The harmonics of rodent pulmonary hypertension models. International journal of clinical practice. Supplement, 172, 1-2Bogaard, Harm J; Al Husseini, Aysar; Farkas, Laszlo; Farkas, Daniela; Gomez-Arroyo, Jose; Abbate, Antonio; Voelkel, Norbert F . Severe pulmonary hypertension: The role of metabolic and endocrine disorders. Pulmonary circulation, 2 2, 148-54Voelkel, Norbert F; Gomez-Arroyo, Jose; Mizuno, Shiro . COPD/emphysema: The vascular story. Pulmonary circulation, 1 3, 320-6