Howard G. Shertzer, PhD

The major research theme involves the regulation of redox homeostasis in cells and tissues. A current focus regards the role of oxidative stress in mediating human disease conditions, and developing strategies for reducing oxidative stress and resulting dysfunction. My group is examining the regulation of the expression and intracellular targeting of enzymes involved in oxidative stress signaling pathways, such as members of the aromatic hydrocarbon and electrophile gene batteries, with an emphasis on mi...