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Aaron P. Seitz, MD

Assistant Professor of Clinical

Surgery | College of Medicine

Education/Credentials
  • Fellowship: University Of Cincinnati (Surgical Critical Care )
  • Residency: University of CIncinnati (General Surgery)
  • Medical Degree: University of Cincinnati College of Medicine
  • Master: University of Cincinnati (Physiology)
  • Bachelor: Iowa State University (Chemical Engineering)
Board Certifications & Licenses

American Board of Surgery (Surgery Critical Care) (Certification Date: 2021-10-04) - (Recertification Date: 2023-11-04)
American Board of Surgery (Certification Date: 2020-11-18) - (Recertification Date: 2023-10-31)

Specialties

Surgery-Critical Care

Contact Information

Clinical Interests

Critical Care Surgery

General Surgery

Trauma

Abdominal Hernia

Acalculous Cholecystitis

Appendicitis

Bile Duct Stones

Biliary Dyskinesia

Billiary Disease

Bleeding in the Small Bowel

Bowel Obstruction

Cholecystolithiasis

Choledocholithiasis

Cholelithiasis

Colonic Diverticulitis

Diverticular Disease

Diverticulitis

Femoral Hernia

Fractured Ribs

Gallbladder Disease

Gallbladder Inflammation (Cholecystitis)

Gallstones

Groin Hernias

Hernia

Lung Collapse (Pneumothorax)

Peritonitis

Pilonidal Cyst

Pilonidal Dimple

Pilonidal Sinus

Pyloric Stenosis

Traumatic Injury

Umbilical Hernia

Ventral Hernia

Peer Reviewed Publications

Niziolek, Grace M; Hoehn, Richard S; Seitz, Aaron P; Jernigan, Peter L; Makley, Amy T; Gulbins, Erich; Edwards, Michael J; Goodman, Michael D 2021. The Role of Acid Sphingomyelinase Inhibition in Repetitive Mild Traumatic Brain Injury. The Journal of surgical research, 259 , 296-304

Seitz, Aaron; Baker, Jennifer E; Levinsky, Nick C; Morris, Mackenzie C; Edwards, Michael J; Gulbins, Erich; Blakeman, Thomas C; Rodriquez, Dario; Branson, Richard D; Goodman, Michael 2021. Antimicrobial coating prevents ventilator-associated pneumonia in a 72 hour large animal model. The Journal of surgical research, 267 , 424-431

Baker, Jennifer E; Seitz, Aaron P; Boudreau, Ryan M; Skinner, Mitchell J; Beydoun, Ahmed; Kaval, Necati; Caldwell, Charles C; Gulbins, Erich; Edwards, Michael J; Gobble, Ryan M 2020. Doxycycline-Coated Silicone Breast Implants Reduce Acute Surgical-Site Infection and Inflammation. Plastic and reconstructive surgery, 146 5, 1029-1041

Hoehn, Richard S; Seitz, Aaron P; Singer, Kathleen E; Thompson, Jonathan R; Watkins, Brad M 2019. Enhanced Recovery Protocol for Laparoscopic Sleeve Gastrectomy: Are Narcotics Necessary? Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 23 8, 1541-1546

Seitz, Aaron P; Schumacher, Fabian; Baker, Jennifer; Soddemann, Matthias; Wilker, Barbara; Caldwell, Charles C; Gobble, Ryan M; Kamler, Markus; Becker, Katrin Anne; Beck, Sascha; Kleuser, Burkhard; Edwards, Michael J; Gulbins, Erich 2019. Sphingosine-coating of plastic surfaces prevents ventilator-associated pneumonia. Journal of molecular medicine (Berlin, Germany), 97 8, 1195-1211

Becker, Katrin Anne; Riethmüller, Joachim; Seitz, Aaron P; Gardner, Aaron; Boudreau, Ryan; Kamler, Markus; Kleuser, Burkhard; Schuchman, Edward; Caldwell, Charles C; Edwards, Michael J; Grassmé, Heike; Brodlie, Malcolm; Gulbins, Erich 2018. Sphingolipids as targets for inhalation treatment of cystic fibrosis. Advanced drug delivery reviews, ,

Chang, Alex L; Kim, Young; Seitz, Aaron P; Schuster, Rebecca M; Lentsch, Alex B; Pritts, Timothy A 2017. Erythrocyte-Derived Microparticles Activate Pulmonary Endothelial Cells in a Murine Model of Transfusion. Shock (Augusta, Ga.), 47 5, 632-637

Chang, Alex L; Kim, Young; Seitz, Aaron P; Schuster, Rebecca M; Pritts, Timothy A 2017. pH modulation ameliorates the red blood cell storage lesion in a murine model of transfusion. The Journal of surgical research, 212 , 54-59

Grassmé, Heike; Henry, Brian; Ziobro, Regan; Becker, Katrin Anne; Riethmüller, Joachim; Gardner, Aaron; Seitz, Aaron P; Steinmann, Joerg; Lang, Stephan; Ward, Christopher; Schuchman, Edward H; Caldwell, Charles C; Kamler, Markus; Edwards, Michael J; Brodlie, Malcolm; Gulbins, Erich 2017. ?1-Integrin Accumulates in Cystic Fibrosis Luminal Airway Epithelial Membranes and Decreases Sphingosine, Promoting Bacterial Infections. Cell host & microbe, 21 6, 707-718.e8

Kunz, Natalia; Xia, Brent T; Kalies, Kai-Uwe; Klinger, Matthias; Gemoll, Timo; Habermann, Jens K; Whitacre, Brynne E; Seitz, Aaron P; Kalies, Kathrin; Caldwell, Charles C 2017. Cell-Derived Nanoparticles are Endogenous Modulators of Sepsis With Therapeutic Potential. Shock (Augusta, Ga.), 48 3, 346-354

Rice, Teresa C; Pugh, Amanda M; Seitz, Aaron P; Gulbins, Erich; Nomellini, Vanessa; Caldwell, Charles C 2017. Sphingosine rescues aged mice from pulmonary pseudomonas infection. The Journal of surgical research, 219 , 354-359

Rice, Teresa C; Pugh, Amanda M; Xia, Brent T; Seitz, Aaron P; Whitacre, Brynne E; Gulbins, Erich; Caldwell, Charles C 2017. Bronchoalveolar Lavage Microvesicles Protect Burn-Injured Mice from Pulmonary Infection. Journal of the American College of Surgeons, 225 4, 538-547

Hoehn, Richard S; Seitz, Aaron P; Jernigan, Peter L; Gulbins, Erich; Edwards, Michael J 2016. Ischemia/Reperfusion Injury Alters Sphingolipid Metabolism in the Gut. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 39 4, 1262-70

Rice, Teresa C; Seitz, Aaron P; Edwards, Michael J; Gulbins, Erich; Caldwell, Charles C 2016. Frontline Science: Sphingosine rescues burn-injured mice from pulmonary Pseudomonas aeruginosa infection. Journal of leukocyte biology, 100 6, 1233-1237

Managò, Antonella; Becker, Katrin Anne; Carpinteiro, Alexander; Wilker, Barbara; Soddemann, Matthias; Seitz, Aaron P; Edwards, Michael J; Grassmé, Heike; Szabò, Ildiko; Gulbins, Erich 2015. Pseudomonas aeruginosa pyocyanin induces neutrophil death via mitochondrial reactive oxygen species and mitochondrial acid sphingomyelinase. Antioxidants & redox signaling, 22 13, 1097-110

Seitz, Aaron P; Grassmé, Heike; Edwards, Michael J; Pewzner-Jung, Yael; Gulbins, Erich 2015. Ceramide and sphingosine in pulmonary infections. Biological chemistry, 396 6-7, 611-20

Kasten, Kevin R; Prakash, Priya S; Unsinger, Jacqueline; Goetzman, Holly S; England, Lisa G; Cave, Cindy M; Seitz, Aaron P; Mazuski, Cristina N; Zhou, Tony T; Morre, Michel; Hotchkiss, Richard S; Hildeman, David A; Caldwell, Charles C 2010. Interleukin-7 (IL-7) treatment accelerates neutrophil recruitment through gamma delta T-cell IL-17 production in a murine model of sepsis. Infection and immunity, 78 11, 4714-22

Kasten, Kevin R; Tschöp, Johannes; Goetzman, Holly S; England, Lisa G; Dattilo, Jonathan R; Cave, Cindy M; Seitz, Aaron P; Hildeman, David A; Caldwell, Charles C 2010. T-cell activation differentially mediates the host response to sepsis. Shock (Augusta, Ga.), 34 4, 377-83

Becker K.; Caldwell C.; Edwards M.; Gulbins E.; Kamler M.; Koch A.; Li X.; Schuchman E.; Seitz A.; Steinmann J. 11-01-2017. Neutrophils Kill Reactive Oxygen Species-Resistant Pseudomonas aeruginosa by Sphingosine Cellular Physiology and Biochemistry, 43 4, 1603-1616

Becker K.;Li X.;Seitz A.;Steinmann J.;Koch A.;Schuchman E.;Kamler M.;Edwards M.;Caldwell C.;Gulbins E. 11-01-2017. Neutrophils Kill Reactive Oxygen Species-Resistant Pseudomonas aeruginosa by Sphingosine Cellular Physiology and Biochemistry, 43 4, 1603-1616

Becker K.; Boudreau R.; Caldwell C.; Couch C.; Edwards M.; Gulbins E.; Martin G.; Seitz A. 10-01-2017. Sphingosine's role in epithelial host defense: A natural antimicrobial and novel therapeutic Biochimie, 141 , 91-96

Martin G.;Boudreau R.;Couch C.;Becker K.;Edwards M.;Caldwell C.;Gulbins E.;Seitz A. 10-01-2017. Sphingosine's role in epithelial host defense: A natural antimicrobial and novel therapeutic Biochimie, 141 , 91-96

Hoehn R.; Seitz A.; Singer K.; Thompson J.; Watkins B. 08-15-2019. Enhanced Recovery Protocol for Laparoscopic Sleeve Gastrectomy: Are Narcotics Necessary? Journal of Gastrointestinal Surgery, 23 8, 1541-1546

Hoehn R.S.;Seitz A.P.;Singer K.E.;Thompson J.R.;Watkins B.M. 08-15-2019. Enhanced Recovery Protocol for Laparoscopic Sleeve Gastrectomy: Are Narcotics Necessary? Journal of Gastrointestinal Surgery, 23 8, 1541-1546

Becker K.; Edwards M.; Grassmé H.; Gulbins E.; Jernigan P.; Kahl B.; Keitsch S.; Lang S.; Sehl C.; Seitz A.; Tavakoli Tabazavareh S. 05-17-2016. Lack of Sphingosine Causes Susceptibility to Pulmonary Staphylococcus Aureus Infections in Cystic Fi Cellular Physiology and Biochemistry, 38 6, 2094-2102

Tavakoli Tabazavareh S.;Seitz A.;Jernigan P.;Sehl C.;Keitsch S.;Lang S.;Kahl B.;Edwards M.;Grassmé H.;Gulbins E.;Becker K. 05-17-2016. Lack of Sphingosine Causes Susceptibility to Pulmonary Staphylococcus Aureus Infections in Cystic Fi Cellular Physiology and Biochemistry, 38 6, 2094-2102

Becker K.; Caldwell C.; Edwards M.; Fahsel B.; Fraunholz M.; Grassmé H.; Gulbins E.; Keitsch S.; Kemper H.; Kohnen M.; Li C.; Mayeres J.; Sehl C.; Seitz A.; Soddemann M.; Wilker B. 01-01-2018. Staphylococcus aureus alpha-toxin disrupts endothelial-cell tight junctions via acid sphingomyelinas Infection and Immunity, 86 1,

Becker K.;Fahsel B.;Kemper H.;Mayeres J.;Li C.;Wilker B.;Keitsch S.;Soddemann M.;Sehl C.;Kohnen M.;Edwards M.;Grassmé H.;Caldwell C.;Seitz A.;Fraunholz M.;Gulbins E. 01-01-2018. Staphylococcus aureus alpha-toxin disrupts endothelial-cell tight junctions via acid sphingomyelinas Infection and Immunity, 86 1,

Becker K.; Beckmann N.; Carpinteiro A.; Edelmann B.; Gulbins E.; Helfrich I.; Hessler G.; Seitz A.; Soddemann M.; Wilker B. 01-01-2016. Role of Acid Sphingomyelinase-Induced Signaling in Melanoma Cells for Hematogenous Tumor Metastasis Cellular Physiology and Biochemistry, 38 1, 1-14

Edwards M.; Grassme H.; Gulbins E.; Japtok L.; Kleuser B.; Lammas D.; Li C.; Peng H.; Riehle A.; Seitz A.; Soddemann M.; Wilker B.; Zhang Y. 01-01-2016. Inhibition of neutral sphingomyelinase protects mice against systemic tuberculosis Frontiers in Bioscience - Elite, 8 2, 311-325

Carpinteiro A.;Beckmann N.;Seitz A.;Hessler G.;Wilker B.;Soddemann M.;Helfrich I.;Edelmann B.;Gulbins E.;Becker K. 01-01-2016. Role of Acid Sphingomyelinase-Induced Signaling in Melanoma Cells for Hematogenous Tumor Metastasis Cellular Physiology and Biochemistry, 38 1, 1-14

Li C.;Peng H.;Japtok L.;Seitz A.;Riehle A.;Wilker B.;Soddemann M.;Kleuser B.;Edwards M.;Lammas D.;Zhang Y.;Gulbins E.;Grassme H. 01-01-2016. Inhibition of neutral sphingomyelinase protects mice against systemic tuberculosis Frontiers in Bioscience - Elite, 8 2, 311-325

Baker, Jennifer E; Boudreau, Ryan M; Seitz, Aaron P; Caldwell, Charles C; Gulbins, Erich; Edwards, Michael J . Sphingolipids and Innate Immunity: A New Approach to Infection in the Post-Antibiotic Era? Surgical infections, 19 8, 792-803