Education/CredentialsPh.D.: University of Colorado (Toxicology)Pharm.D.: University of Kentucky (Pharmacy)B.S.: University of Wyoming (Molecular Biology)B.S.: University of Wyoming (Pharmacy) Contact Information Kettering Lab Complex 163 Email reichajf@ucmail.uc.edu Peer Reviewed Publications Brawley, Hayley N; Reichard, John F; Shennara, Khaled; Lovett, Dennis; Babcock, Lyle; MacDonald, Austin; Easter, Benjamin; Soares, Michael; Mateus, Jaime; Rosenberg, Marissa; Nowadly, Craig 2026. Comparative Analysis of Pharmaceutical Content Following Spaceflight and Vacuum Exposure During Commercial Extravehicular Activity. Wilderness & environmental medicine, , 10806032261426910Brawley, Hayley N; Reichard, John F; Shennara, Khaled; Lovett, Dennis; Babcock, Lyle; MacDonald, Austin; Easter, Benjamin; Soares, Michael; Mateus, Jaime; Rosenberg, Marissa; Nowadly, Craig 2026. Comparative Analysis of Pharmaceutical Content Following Spaceflight and Vacuum Exposure During Commercial Extravehicular Activity. Wilderness & environmental medicine, , 10806032261426910Massarsky, Andrey; Evans, Veneese J B; Fung, Ernest S; Yang, Lisa G L; Rogers, Keegan L; Buerger, Amanda N; Maier, Andrew; Reichard, John F 2026. A framework for assessing the safety of degraded pharmaceuticals for long-duration space missions - Part 1: framework development. Critical reviews in toxicology, , 1-34Massarsky, Andrey; Evans, Veneese J B; Fung, Ernest S; Yang, Lisa G L; Rogers, Keegan L; Buerger, Amanda N; Maier, Andrew; Reichard, John F 2026. A framework for assessing the safety of degraded pharmaceuticals for long-duration space missions - Part 1: framework development. Critical reviews in toxicology, , 1-34Obariase, Efosa; Reichard, John F 2026. Dissolution of Inorganic Lead (Pb) in Synthetic Sweat: Implications for Dermal Exposure and Occupational Risk. Toxics, 14 3, Obariase, Efosa; Reichard, John F 2026. Dissolution of Inorganic Lead (Pb) in Synthetic Sweat: Implications for Dermal Exposure and Occupational Risk. Toxics, 14 3, Plante, Ianik; Daniels, Vernie; Young, Millennia; Gaza, Ramona; Wu, Honglu; Reichard, John F 2025. The long-term stability of solid-state oral pharmaceuticals exposed to simulated intravehicular space radiation. NPJ microgravity, 11 1, 17Plante, Ianik; Daniels, Vernie; Young, Millennia; Gaza, Ramona; Wu, Honglu; Reichard, John F 2025. The long-term stability of solid-state oral pharmaceuticals exposed to simulated intravehicular space radiation. NPJ microgravity, 11 1, 17Reichard, John F; Barned, Swade; Mendy, Angelico; Pinney, Susan M 2025. Radon Exposure to the General Population of the Fernald Community Cohort. Atmosphere, 16 8, Reichard, John F; Barned, Swade; Mendy, Angelico; Pinney, Susan M 2025. Radon Exposure to the General Population of the Fernald Community Cohort. Atmosphere, 16 8, Reichard, Julia; Wolff, Philip; Xie, Song; Zuo, Ke; Fullio, Camila L; Du, Jian; Graff, Severin; Linde, Jenice; Yildiz, Can Bora; Pitschelatow, Georg; Nabbefeld, Gerion; Dorp, Lilli; Vollmer, Johanna; Biemans, Linda; Kempf, Shirley; Singh, Minali; Mohan, K Naga; Kuo, Chao-Chung; Vogel, Tanja; Carloni, Paolo; Musall, Simon; Zimmer-Bensch, Geraldine 2025. DNMT1-mediated regulation of somatostatin-positive interneuron migration impacts cortical architecture and function. Nature communications, 16 1, 6834Reichard, Julia; Wolff, Philip; Xie, Song; Zuo, Ke; Fullio, Camila L; Du, Jian; Graff, Severin; Linde, Jenice; Yildiz, Can Bora; Pitschelatow, Georg; Nabbefeld, Gerion; Dorp, Lilli; Vollmer, Johanna; Biemans, Linda; Kempf, Shirley; Singh, Minali; Mohan, K Naga; Kuo, Chao-Chung; Vogel, Tanja; Carloni, Paolo; Musall, Simon; Zimmer-Bensch, Geraldine 2025. DNMT1-mediated regulation of somatostatin-positive interneuron migration impacts cortical architecture and function. Nature communications, 16 1, 6834Udell, Bradley J; Stratton, Christian; Irvine, Kathryn M; Straw, Bethany Rose; Reichard, Jonathan D; Gaulke, Sarah; Coleman, Jeremy T H; Tousley, Frank C; Schuhmann, Andrea N; Inman, Richard D; Turner, Melinda; Nystrom, Sarah; Reichert, Brian E 2025. Integrated distribution modeling resolves asynchrony between bat population impacts and occupancy trends through latent abundance. Communications biology, 8 1, 832Udell, Bradley J; Stratton, Christian; Irvine, Kathryn M; Straw, Bethany Rose; Reichard, Jonathan D; Gaulke, Sarah; Coleman, Jeremy T H; Tousley, Frank C; Schuhmann, Andrea N; Inman, Richard D; Turner, Melinda; Nystrom, Sarah; Reichert, Brian E 2025. Integrated distribution modeling resolves asynchrony between bat population impacts and occupancy trends through latent abundance. Communications biology, 8 1, 832Niang, Mamadou; Reponen, Tiina; Talaska, Glenn; Ying, Jun; Reichard, John F; Pecquet, Alison; Maier, Andrew 2024. Preliminary human health risk assessment of antibiotic exposures in human waste handling occupations. Journal of occupational and environmental hygiene, 21 10, 721-740El-Khoury, Bashir B; Ray, Kristi L; Altchuler, Steven I; Reichard, John F; Dukes, Charles H 2023. Selective Serotonin Reuptake Inhibitors and Other Treatment Modalities for Deep Space Missions. Aerospace medicine and human performance, 94 11, 843-851Niang, Mamadou; Reichard, John F; Maier, Andrew; Talaska, Glenn; Ying, Jun; Santo Domingo, Jorge; Varughese, Eunice; Boczek, Laura; Huff, Emma; Reponen, Tiina 2023. Ciprofloxacin- and azithromycin-resistant bacteria in a wastewater treatment plant. Journal of occupational and environmental hygiene, 20 5-6, 219-225Reichard, J F; Phelps, S E; Lehnhardt, K R; Young, M; Easter, B D 2023. The effect of long-term spaceflight on drug potency and the risk of medication failure. NPJ microgravity, 9 1, 35Jolly, Robert A; Bandara, Suren; Bercu, Joel; Callis, Courtney M; Dolan, David G; Graham, Jessica; HaMai, Diem; Barle, Ester Lovsin; Maier, Andrew; Masuda-Herrera, Melisa; Moudgal, Chandrika; Parker, Jillian A; Reichard, John; Sandhu, Reena; Fung, Ernest S 2022. Setting impurity limits for endogenous substances: Recommendations for a harmonized procedure and an example using fatty acids. Regulatory toxicology and pharmacology : RTP, 134 , 105242Niemeier, Richard Todd; Maier, Andrew; Reichard, John F 2022. Rapid Review of Dermal Penetration and Absorption of Inorganic Lead Compounds for Occupational Risk Assessment. Annals of work exposures and health, 66 3, 291-311Pilarczyk, Marcin; Fazel-Najafabadi, Mehdi; Kouril, Michal; Shamsaei, Behrouz; Vasiliauskas, Juozas; Niu, Wen; Mahi, Naim; Zhang, Lixia; Clark, Nicholas A; Ren, Yan; White, Shana; Karim, Rashid; Xu, Huan; Biesiada, Jacek; Bennett, Mark F; Davidson, Sarah E; Reichard, John F; Roberts, Kurt; Stathias, Vasileios; Koleti, Amar; Vidovic, Dusica; Clarke, Daniel J B; Schürer, Stephan C; Ma'ayan, Avi; Meller, Jarek; Medvedovic, Mario 2022. Connecting omics signatures and revealing biological mechanisms with iLINCS. Nature communications, 13 1, 4678Haber, Lynne T; Reichard, John F; Henning, Alice K; Dawson, Peter; Chinthrajah, R Sharon; Sindher, Sayantani B; Long, Andrew; Vincent, Melissa J; Nadeau, Kari C; Allen, Bruce C 2021. Bayesian hierarchical evaluation of dose-response for peanut allergy in clinical trial screening. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 151 , 112125Ishau, Simileoluwa; Reichard, John F; Maier, Andrew; Niang, Mamadou; Yermakov, Michael; Grinshpun, Sergey A 2020. Estimated dermal exposure to nebulized pharmaceuticals for a simulated home healthcare worker scenario. Journal of occupational and environmental hygiene, 17 4, 193-205Juarez, Paul D; Tabatabai, Mohammad; Valdez, Robert Burciaga; Hood, Darryl B; Im, Wansoo; Mouton, Charles; Colen, Cynthia; Al-Hamdan, Mohammad Z; Matthews-Juarez, Patricia; Lichtveld, Maureen Y; Sarpong, Daniel; Ramesh, Aramandla; Langston, Michael A; Rogers, Gary L; Phillips, Charles A; Reichard, John F; Donneyong, Macarius M; Blot, William 2020. The Effects of Social, Personal, and Behavioral Risk Factors and PM2.5 on Cardio-Metabolic Disparities in a Cohort of Community Health Center Patients. International journal of environmental research and public health, 17 10, Symmank, Judit; Bayer, Cathrin; Reichard, Julia; Pensold, Daniel; Zimmer-Bensch, Geraldine 2020. Neuronal Lhx1 expression is regulated by DNMT1-dependent modulation of histone marks. Epigenetics, 15 11, 1259-1274Cifuentes, Patricia; Reichard, John; Im, Wansoo; Smith, Sakima; Colen, Cynthia; Giurgescu, Carmen; Williams, Karen Patricia; Gillespie, Shannon; Juarez, Paul D; Hood, Darryl B 2019. Application of the Public Health Exposome Framework to Estimate Phenotypes of Resilience in a Model Ohio African-American Women's Cohort. Journal of urban health : bulletin of the New York Academy of Medicine, 96 Suppl 1, 57-71Frank, Evan; Ishau, Simileoluwa; Maier, Andrew; Reutman, Susan; Reichard, John F 2019. An occupational exposure limit (OEL) approach to protect home healthcare workers exposed to common nebulized drugs. Regulatory toxicology and pharmacology : RTP, 106 , 251-261Keenan, Alexandra B; Jenkins, Sherry L; Jagodnik, Kathleen M; Koplev, Simon; He, Edward; Torre, Denis; Wang, Zichen; Dohlman, Anders B; Silverstein, Moshe C; Lachmann, Alexander; Kuleshov, Maxim V; Ma'ayan, Avi; Stathias, Vasileios; Terryn, Raymond; Cooper, Daniel; Forlin, Michele; Koleti, Amar; Vidovic, Dusica; Chung, Caty; Schürer, Stephan C; Vasiliauskas, Jouzas; Pilarczyk, Marcin; Shamsaei, Behrouz; Fazel, Mehdi; Ren, Yan; Niu, Wen; Clark, Nicholas A; White, Shana; Mahi, Naim; Zhang, Lixia; Kouril, Michal; Reichard, John F; Sivaganesan, Siva; Medvedovic, Mario; Meller, Jaroslaw; Koch, Rick J; Birtwistle, Marc R; Iyengar, Ravi; Sobie, Eric A; Azeloglu, Evren U; Kaye, Julia; Osterloh, Jeannette; Haston, Kelly; Kalra, Jaslin; Finkbiener, Steve; Li, Jonathan; Milani, Pamela; Adam, Miriam; Escalante-Chong, Renan; Sachs, Karen; Lenail, Alex; Ramamoorthy, Divya; Fraenkel, Ernest; Daigle, Gavin; Hussain, Uzma; Coye, Alyssa; Rothstein, Jeffrey; Sareen, Dhruv; Ornelas, Loren; Banuelos, Maria; Mandefro, Berhan; Ho, Ritchie; Svendsen, Clive N; Lim, Ryan G; Stocksdale, Jennifer; Casale, Malcolm S; Thompson, Terri G; Wu, Jie; Thompson, Leslie M; Dardov, Victoria; Venkatraman, Vidya; Matlock, Andrea; Van Eyk, Jennifer E; Jaffe, Jacob D; Papanastasiou, Malvina; Subramanian, Aravind; Golub, Todd R; Erickson, Sean D; Fallahi-Sichani, Mohammad; Hafner, Marc; Gray, Nathanael S; Lin, Jia-Ren; Mills, Caitlin E; Muhlich, Jeremy L; Niepel, Mario; Shamu, Caroline E; Williams, Elizabeth H; Wrobel, David; Sorger, Peter K; Heiser, Laura M; Gray, Joe W; Korkola, James E; Mills, Gordon B; LaBarge, Mark; Feiler, Heidi S; Dane, Mark A; Bucher, Elmar; Nederlof, Michel; Sudar, Damir; Gross, Sean; Kilburn, David F; Smith, Rebecca; Devlin, Kaylyn; Margolis, Ron; Derr, Leslie; Lee, Albert; Pillai, Ajay 2018. The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations. Cell systems, 6 1, 13-24Dourson, Michael L; Higginbotham, Jeri; Crum, Jeff; Burleigh-Flayer, Heather; Nance, Patricia; Forsberg, Norman D; Lafranconi, Mark; Reichard, John 2017. Update: Mode of action (MOA) for liver tumors induced by oral exposure to 1,4-dioxane. Regulatory toxicology and pharmacology : RTP, 88 , 45-55Reichard, John F; Haber, Lynne T 2016. Mode-of-action evaluation for the effect of trans fatty acids on low-density lipoprotein cholesterol. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 98 Pt B, 282-294Reichard, John F; Maier, M Andrew; Naumann, Bruce D; Pecquet, Alison M; Pfister, Thomas; Sandhu, Reena; Sargent, Edward V; Streeter, Anthony J; Weideman, Patricia A 2016. Toxicokinetic and toxicodynamic considerations when deriving health-based exposure limits for pharmaceuticals. Regulatory toxicology and pharmacology : RTP, 79 Suppl 1 , S67-78Budinsky, R A; Schrenk, D; Simon, T; Van den Berg, M; Reichard, J F; Silkworth, J B; Aylward, L L; Brix, A; Gasiewicz, T; Kaminski, N; Perdew, G; Starr, T B; Walker, N J; Rowlands, J C 2014. Mode of action and dose-response framework analysis for receptor-mediated toxicity: The aryl hydrocarbon receptor as a case study. Critical reviews in toxicology, 44 1, 83-119Dourson, Michael; Reichard, John; Nance, Patricia; Burleigh-Flayer, Heather; Parker, Ann; Vincent, Melissa; McConnell, Ernest E 2014. Mode of action analysis for liver tumors from oral 1,4-dioxane exposures and evidence-based dose response assessment. Regulatory toxicology and pharmacology : RTP, 68 3, 387-401Chen, Jing; Hu, Zhen; Phatak, Mukta; Reichard, John; Freudenberg, Johannes M; Sivaganesan, Siva; Medvedovic, Mario 2013. Genome-wide signatures of transcription factor activity: connecting transcription factors, disease, and small molecules. PLoS computational biology, 9 9, e1003198Muñoz-Garcia, Agustí; Ro, Jennifer; Reichard, Jonathan D; Kunz, Thomas H; Williams, Joseph B 2012. Cutaneous water loss and lipids of the stratum corneum in two syntopic species of bats. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 161 2, 208-15States, J Christopher; Barchowsky, Aaron; Cartwright, Iain L; Reichard, John F; Futscher, Bernard W; Lantz, R Clark 2011. Arsenic toxicology: translating between experimental models and human pathology. Environmental health perspectives, 119 10, 1356-63Reichard, John F; Puga, Alvaro 2010. Effects of arsenic exposure on DNA methylation and epigenetic gene regulation. Epigenomics, 2 1, 87-104Reichard, Jonathan D; Prajapati, Suresh I; Austad, Steven N; Keller, Charles; Kunz, Thomas H 2010. Thermal windows on Brazilian free-tailed bats facilitate thermoregulation during prolonged flight. Integrative and comparative biology, 50 3, 358-70Sartor, Maureen A; Schnekenburger, Michael; Marlowe, Jennifer L; Reichard, John F; Wang, Ying; Fan, Yunxia; Ma, Ci; Karyala, Saikumar; Halbleib, Danielle; Liu, Xiangdong; Medvedovic, Mario; Puga, Alvaro 2009. Genomewide analysis of aryl hydrocarbon receptor binding targets reveals an extensive array of gene clusters that control morphogenetic and developmental programs. Environmental health perspectives, 117 7, 1139-46Reichard, John F; Sartor, Maureen A; Puga, Alvaro 2008. BACH1 is a specific repressor of HMOX1 that is inactivated by arsenite. The Journal of biological chemistry, 283 33, 22363-70Reichard, John F; Motz, Gregory T; Puga, Alvaro 2007. Heme oxygenase-1 induction by NRF2 requires inactivation of the transcriptional repressor BACH1. Nucleic acids research, 35 21, 7074-86Reichard, John F; Schnekenburger, Michael; Puga, Alvaro 2007. Long term low-dose arsenic exposure induces loss of DNA methylation. Biochemical and biophysical research communications, 352 1, 188-92Reichard, John F; Petersen, Dennis R 2006. Involvement of phosphatidylinositol 3-kinase and extracellular-regulated kinase in hepatic stellate cell antioxidant response and myofibroblastic transdifferentiation. Archives of biochemistry and biophysics, 446 2, 111-8Kann, Simone; Estes, Cameron; Reichard, John F; Huang, Ming-Ya; Sartor, Maureen A; Schwemberger, Sandy; Chen, Ying; Dalton, Timothy P; Shertzer, Howard G; Xia, Ying; Puga, Alvaro 2005. Butylhydroquinone protects cells genetically deficient in glutathione biosynthesis from arsenite-induced apoptosis without significantly changing their prooxidant status. Toxicological sciences : an official journal of the Society of Toxicology, 87 2, 365-84Kann, Simone; Huang, Ming-Ya; Estes, Cameron; Reichard, John F; Sartor, Maureen A; Xia, Ying; Puga, Alvaro 2005. Arsenite-induced aryl hydrocarbon receptor nuclear translocation results in additive induction of phase I genes and synergistic induction of phase II genes. Molecular pharmacology, 68 2, 336-46Reichard, John F; Dalton, Timothy P; Shertzer, Howard G; Puga, Alvaro 2005. Induction of oxidative stress responses by dioxin and other ligands of the aryl hydrocarbon receptor. Dose-response : a publication of International Hormesis Society, 3 3, 306-31Reichard, John F; Petersen, Dennis R 2004. Hepatic stellate cells lack AP-1 responsiveness to electrophiles and phorbol 12-myristate-13-acetate. Biochemical and biophysical research communications, 322 3, 842-53Reichard, John F; Doorn, Jonathan A; Simon, Franz; Taylor, Melinda S; Petersen, Dennis R 2003. Characterization of multidrug resistance-associated protein 2 in the hepatocellular disposition of 4-hydroxynonenal. Archives of biochemistry and biophysics, 411 2, 243-50Reichard, J F; Vasiliou, V; Petersen, D R 2000. Characterization of 4-hydroxy-2-nonenal metabolism in stellate cell lines derived from normal and cirrhotic rat liver. Biochimica et biophysica acta, 1487 2-3, 222-32Hartley, D P; Kolaja, K L; Reichard, J; Petersen, D R 1999. 4-Hydroxynonenal and malondialdehyde hepatic protein adducts in rats treated with carbon tetrachloride: immunochemical detection and lobular localization. Toxicology and applied pharmacology, 161 1, 23-33 Plante I.; Daniels V.; Young M.; Gaza R.; Wu H.; Reichard J.F. 12-01-2025. The long-term stability of solid-state oral pharmaceuticals exposed to simulated intravehicular spac Npj Microgravity, 11 1, Reichard J.F.; Phelps S.E.; Lehnhardt K.R.; Young M.; Easter B.D. 12-01-2023. The effect of long-term spaceflight on drug potency and the risk of medication failure Npj Microgravity, 9 1, Reichard J.; Puga A. 08-08-2012. Epigenetic Histone Changes in the Toxicologic Mode of Action of Arsenic Toxicology and Epigenetics, , 339-356 Reichard J.F.; Barned S.; Mendy A.; Pinney S.M. 08-01-2025. Radon Exposure to the General Population of the Fernald Community Cohort Atmosphere, 16 8, Obariase E.; Reichard J.F. 03-01-2026. Dissolution of Inorganic Lead (Pb) in Synthetic Sweat: Implications for Dermal Exposure and Occupati Toxics, 14 3, Brawley H.N.; Reichard J.F.; Shennara K.; Lovett D.; Babcock L.; MacDonald A.; Easter B.; Soares M.; Mateus J.; Rosenberg M.; Nowadly C. 01-01-2026. Comparative Analysis of Pharmaceutical Content Following Spaceflight and Vacuum Exposure During Comm Wilderness and Environmental Medicine, , Massarsky A.; Evans V.J.B.; Fung E.S.; Yang L.G.L.; Rogers K.L.; Buerger A.N.; Maier A.; Reichard J.F. 01-01-2026. A framework for assessing the safety of degraded pharmaceuticals for long-duration space missions - Critical Reviews in Toxicology, , Massarsky A.; Evans V.J.B.; Fung E.S.; Yang L.G.L.; Rogers K.L.; Buerger A.N.; Maier A.; Reichard J.F. 01-01-2026. A framework for assessing the safety of degraded pharmaceuticals for long-duration space missions - Critical Reviews in Toxicology, ,
Peer Reviewed Publications Brawley, Hayley N; Reichard, John F; Shennara, Khaled; Lovett, Dennis; Babcock, Lyle; MacDonald, Austin; Easter, Benjamin; Soares, Michael; Mateus, Jaime; Rosenberg, Marissa; Nowadly, Craig 2026. Comparative Analysis of Pharmaceutical Content Following Spaceflight and Vacuum Exposure During Commercial Extravehicular Activity. Wilderness & environmental medicine, , 10806032261426910Brawley, Hayley N; Reichard, John F; Shennara, Khaled; Lovett, Dennis; Babcock, Lyle; MacDonald, Austin; Easter, Benjamin; Soares, Michael; Mateus, Jaime; Rosenberg, Marissa; Nowadly, Craig 2026. Comparative Analysis of Pharmaceutical Content Following Spaceflight and Vacuum Exposure During Commercial Extravehicular Activity. Wilderness & environmental medicine, , 10806032261426910Massarsky, Andrey; Evans, Veneese J B; Fung, Ernest S; Yang, Lisa G L; Rogers, Keegan L; Buerger, Amanda N; Maier, Andrew; Reichard, John F 2026. A framework for assessing the safety of degraded pharmaceuticals for long-duration space missions - Part 1: framework development. Critical reviews in toxicology, , 1-34Massarsky, Andrey; Evans, Veneese J B; Fung, Ernest S; Yang, Lisa G L; Rogers, Keegan L; Buerger, Amanda N; Maier, Andrew; Reichard, John F 2026. A framework for assessing the safety of degraded pharmaceuticals for long-duration space missions - Part 1: framework development. Critical reviews in toxicology, , 1-34Obariase, Efosa; Reichard, John F 2026. Dissolution of Inorganic Lead (Pb) in Synthetic Sweat: Implications for Dermal Exposure and Occupational Risk. Toxics, 14 3, Obariase, Efosa; Reichard, John F 2026. Dissolution of Inorganic Lead (Pb) in Synthetic Sweat: Implications for Dermal Exposure and Occupational Risk. Toxics, 14 3, Plante, Ianik; Daniels, Vernie; Young, Millennia; Gaza, Ramona; Wu, Honglu; Reichard, John F 2025. The long-term stability of solid-state oral pharmaceuticals exposed to simulated intravehicular space radiation. NPJ microgravity, 11 1, 17Plante, Ianik; Daniels, Vernie; Young, Millennia; Gaza, Ramona; Wu, Honglu; Reichard, John F 2025. The long-term stability of solid-state oral pharmaceuticals exposed to simulated intravehicular space radiation. NPJ microgravity, 11 1, 17Reichard, John F; Barned, Swade; Mendy, Angelico; Pinney, Susan M 2025. Radon Exposure to the General Population of the Fernald Community Cohort. Atmosphere, 16 8, Reichard, John F; Barned, Swade; Mendy, Angelico; Pinney, Susan M 2025. Radon Exposure to the General Population of the Fernald Community Cohort. Atmosphere, 16 8, Reichard, Julia; Wolff, Philip; Xie, Song; Zuo, Ke; Fullio, Camila L; Du, Jian; Graff, Severin; Linde, Jenice; Yildiz, Can Bora; Pitschelatow, Georg; Nabbefeld, Gerion; Dorp, Lilli; Vollmer, Johanna; Biemans, Linda; Kempf, Shirley; Singh, Minali; Mohan, K Naga; Kuo, Chao-Chung; Vogel, Tanja; Carloni, Paolo; Musall, Simon; Zimmer-Bensch, Geraldine 2025. DNMT1-mediated regulation of somatostatin-positive interneuron migration impacts cortical architecture and function. Nature communications, 16 1, 6834Reichard, Julia; Wolff, Philip; Xie, Song; Zuo, Ke; Fullio, Camila L; Du, Jian; Graff, Severin; Linde, Jenice; Yildiz, Can Bora; Pitschelatow, Georg; Nabbefeld, Gerion; Dorp, Lilli; Vollmer, Johanna; Biemans, Linda; Kempf, Shirley; Singh, Minali; Mohan, K Naga; Kuo, Chao-Chung; Vogel, Tanja; Carloni, Paolo; Musall, Simon; Zimmer-Bensch, Geraldine 2025. DNMT1-mediated regulation of somatostatin-positive interneuron migration impacts cortical architecture and function. Nature communications, 16 1, 6834Udell, Bradley J; Stratton, Christian; Irvine, Kathryn M; Straw, Bethany Rose; Reichard, Jonathan D; Gaulke, Sarah; Coleman, Jeremy T H; Tousley, Frank C; Schuhmann, Andrea N; Inman, Richard D; Turner, Melinda; Nystrom, Sarah; Reichert, Brian E 2025. Integrated distribution modeling resolves asynchrony between bat population impacts and occupancy trends through latent abundance. Communications biology, 8 1, 832Udell, Bradley J; Stratton, Christian; Irvine, Kathryn M; Straw, Bethany Rose; Reichard, Jonathan D; Gaulke, Sarah; Coleman, Jeremy T H; Tousley, Frank C; Schuhmann, Andrea N; Inman, Richard D; Turner, Melinda; Nystrom, Sarah; Reichert, Brian E 2025. Integrated distribution modeling resolves asynchrony between bat population impacts and occupancy trends through latent abundance. Communications biology, 8 1, 832Niang, Mamadou; Reponen, Tiina; Talaska, Glenn; Ying, Jun; Reichard, John F; Pecquet, Alison; Maier, Andrew 2024. Preliminary human health risk assessment of antibiotic exposures in human waste handling occupations. Journal of occupational and environmental hygiene, 21 10, 721-740El-Khoury, Bashir B; Ray, Kristi L; Altchuler, Steven I; Reichard, John F; Dukes, Charles H 2023. Selective Serotonin Reuptake Inhibitors and Other Treatment Modalities for Deep Space Missions. Aerospace medicine and human performance, 94 11, 843-851Niang, Mamadou; Reichard, John F; Maier, Andrew; Talaska, Glenn; Ying, Jun; Santo Domingo, Jorge; Varughese, Eunice; Boczek, Laura; Huff, Emma; Reponen, Tiina 2023. Ciprofloxacin- and azithromycin-resistant bacteria in a wastewater treatment plant. Journal of occupational and environmental hygiene, 20 5-6, 219-225Reichard, J F; Phelps, S E; Lehnhardt, K R; Young, M; Easter, B D 2023. The effect of long-term spaceflight on drug potency and the risk of medication failure. NPJ microgravity, 9 1, 35Jolly, Robert A; Bandara, Suren; Bercu, Joel; Callis, Courtney M; Dolan, David G; Graham, Jessica; HaMai, Diem; Barle, Ester Lovsin; Maier, Andrew; Masuda-Herrera, Melisa; Moudgal, Chandrika; Parker, Jillian A; Reichard, John; Sandhu, Reena; Fung, Ernest S 2022. Setting impurity limits for endogenous substances: Recommendations for a harmonized procedure and an example using fatty acids. Regulatory toxicology and pharmacology : RTP, 134 , 105242Niemeier, Richard Todd; Maier, Andrew; Reichard, John F 2022. Rapid Review of Dermal Penetration and Absorption of Inorganic Lead Compounds for Occupational Risk Assessment. Annals of work exposures and health, 66 3, 291-311Pilarczyk, Marcin; Fazel-Najafabadi, Mehdi; Kouril, Michal; Shamsaei, Behrouz; Vasiliauskas, Juozas; Niu, Wen; Mahi, Naim; Zhang, Lixia; Clark, Nicholas A; Ren, Yan; White, Shana; Karim, Rashid; Xu, Huan; Biesiada, Jacek; Bennett, Mark F; Davidson, Sarah E; Reichard, John F; Roberts, Kurt; Stathias, Vasileios; Koleti, Amar; Vidovic, Dusica; Clarke, Daniel J B; Schürer, Stephan C; Ma'ayan, Avi; Meller, Jarek; Medvedovic, Mario 2022. Connecting omics signatures and revealing biological mechanisms with iLINCS. Nature communications, 13 1, 4678Haber, Lynne T; Reichard, John F; Henning, Alice K; Dawson, Peter; Chinthrajah, R Sharon; Sindher, Sayantani B; Long, Andrew; Vincent, Melissa J; Nadeau, Kari C; Allen, Bruce C 2021. Bayesian hierarchical evaluation of dose-response for peanut allergy in clinical trial screening. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 151 , 112125Ishau, Simileoluwa; Reichard, John F; Maier, Andrew; Niang, Mamadou; Yermakov, Michael; Grinshpun, Sergey A 2020. Estimated dermal exposure to nebulized pharmaceuticals for a simulated home healthcare worker scenario. Journal of occupational and environmental hygiene, 17 4, 193-205Juarez, Paul D; Tabatabai, Mohammad; Valdez, Robert Burciaga; Hood, Darryl B; Im, Wansoo; Mouton, Charles; Colen, Cynthia; Al-Hamdan, Mohammad Z; Matthews-Juarez, Patricia; Lichtveld, Maureen Y; Sarpong, Daniel; Ramesh, Aramandla; Langston, Michael A; Rogers, Gary L; Phillips, Charles A; Reichard, John F; Donneyong, Macarius M; Blot, William 2020. The Effects of Social, Personal, and Behavioral Risk Factors and PM2.5 on Cardio-Metabolic Disparities in a Cohort of Community Health Center Patients. International journal of environmental research and public health, 17 10, Symmank, Judit; Bayer, Cathrin; Reichard, Julia; Pensold, Daniel; Zimmer-Bensch, Geraldine 2020. Neuronal Lhx1 expression is regulated by DNMT1-dependent modulation of histone marks. Epigenetics, 15 11, 1259-1274Cifuentes, Patricia; Reichard, John; Im, Wansoo; Smith, Sakima; Colen, Cynthia; Giurgescu, Carmen; Williams, Karen Patricia; Gillespie, Shannon; Juarez, Paul D; Hood, Darryl B 2019. Application of the Public Health Exposome Framework to Estimate Phenotypes of Resilience in a Model Ohio African-American Women's Cohort. Journal of urban health : bulletin of the New York Academy of Medicine, 96 Suppl 1, 57-71Frank, Evan; Ishau, Simileoluwa; Maier, Andrew; Reutman, Susan; Reichard, John F 2019. An occupational exposure limit (OEL) approach to protect home healthcare workers exposed to common nebulized drugs. Regulatory toxicology and pharmacology : RTP, 106 , 251-261Keenan, Alexandra B; Jenkins, Sherry L; Jagodnik, Kathleen M; Koplev, Simon; He, Edward; Torre, Denis; Wang, Zichen; Dohlman, Anders B; Silverstein, Moshe C; Lachmann, Alexander; Kuleshov, Maxim V; Ma'ayan, Avi; Stathias, Vasileios; Terryn, Raymond; Cooper, Daniel; Forlin, Michele; Koleti, Amar; Vidovic, Dusica; Chung, Caty; Schürer, Stephan C; Vasiliauskas, Jouzas; Pilarczyk, Marcin; Shamsaei, Behrouz; Fazel, Mehdi; Ren, Yan; Niu, Wen; Clark, Nicholas A; White, Shana; Mahi, Naim; Zhang, Lixia; Kouril, Michal; Reichard, John F; Sivaganesan, Siva; Medvedovic, Mario; Meller, Jaroslaw; Koch, Rick J; Birtwistle, Marc R; Iyengar, Ravi; Sobie, Eric A; Azeloglu, Evren U; Kaye, Julia; Osterloh, Jeannette; Haston, Kelly; Kalra, Jaslin; Finkbiener, Steve; Li, Jonathan; Milani, Pamela; Adam, Miriam; Escalante-Chong, Renan; Sachs, Karen; Lenail, Alex; Ramamoorthy, Divya; Fraenkel, Ernest; Daigle, Gavin; Hussain, Uzma; Coye, Alyssa; Rothstein, Jeffrey; Sareen, Dhruv; Ornelas, Loren; Banuelos, Maria; Mandefro, Berhan; Ho, Ritchie; Svendsen, Clive N; Lim, Ryan G; Stocksdale, Jennifer; Casale, Malcolm S; Thompson, Terri G; Wu, Jie; Thompson, Leslie M; Dardov, Victoria; Venkatraman, Vidya; Matlock, Andrea; Van Eyk, Jennifer E; Jaffe, Jacob D; Papanastasiou, Malvina; Subramanian, Aravind; Golub, Todd R; Erickson, Sean D; Fallahi-Sichani, Mohammad; Hafner, Marc; Gray, Nathanael S; Lin, Jia-Ren; Mills, Caitlin E; Muhlich, Jeremy L; Niepel, Mario; Shamu, Caroline E; Williams, Elizabeth H; Wrobel, David; Sorger, Peter K; Heiser, Laura M; Gray, Joe W; Korkola, James E; Mills, Gordon B; LaBarge, Mark; Feiler, Heidi S; Dane, Mark A; Bucher, Elmar; Nederlof, Michel; Sudar, Damir; Gross, Sean; Kilburn, David F; Smith, Rebecca; Devlin, Kaylyn; Margolis, Ron; Derr, Leslie; Lee, Albert; Pillai, Ajay 2018. The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations. Cell systems, 6 1, 13-24Dourson, Michael L; Higginbotham, Jeri; Crum, Jeff; Burleigh-Flayer, Heather; Nance, Patricia; Forsberg, Norman D; Lafranconi, Mark; Reichard, John 2017. Update: Mode of action (MOA) for liver tumors induced by oral exposure to 1,4-dioxane. Regulatory toxicology and pharmacology : RTP, 88 , 45-55Reichard, John F; Haber, Lynne T 2016. Mode-of-action evaluation for the effect of trans fatty acids on low-density lipoprotein cholesterol. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 98 Pt B, 282-294Reichard, John F; Maier, M Andrew; Naumann, Bruce D; Pecquet, Alison M; Pfister, Thomas; Sandhu, Reena; Sargent, Edward V; Streeter, Anthony J; Weideman, Patricia A 2016. Toxicokinetic and toxicodynamic considerations when deriving health-based exposure limits for pharmaceuticals. Regulatory toxicology and pharmacology : RTP, 79 Suppl 1 , S67-78Budinsky, R A; Schrenk, D; Simon, T; Van den Berg, M; Reichard, J F; Silkworth, J B; Aylward, L L; Brix, A; Gasiewicz, T; Kaminski, N; Perdew, G; Starr, T B; Walker, N J; Rowlands, J C 2014. Mode of action and dose-response framework analysis for receptor-mediated toxicity: The aryl hydrocarbon receptor as a case study. Critical reviews in toxicology, 44 1, 83-119Dourson, Michael; Reichard, John; Nance, Patricia; Burleigh-Flayer, Heather; Parker, Ann; Vincent, Melissa; McConnell, Ernest E 2014. Mode of action analysis for liver tumors from oral 1,4-dioxane exposures and evidence-based dose response assessment. Regulatory toxicology and pharmacology : RTP, 68 3, 387-401Chen, Jing; Hu, Zhen; Phatak, Mukta; Reichard, John; Freudenberg, Johannes M; Sivaganesan, Siva; Medvedovic, Mario 2013. Genome-wide signatures of transcription factor activity: connecting transcription factors, disease, and small molecules. PLoS computational biology, 9 9, e1003198Muñoz-Garcia, Agustí; Ro, Jennifer; Reichard, Jonathan D; Kunz, Thomas H; Williams, Joseph B 2012. Cutaneous water loss and lipids of the stratum corneum in two syntopic species of bats. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 161 2, 208-15States, J Christopher; Barchowsky, Aaron; Cartwright, Iain L; Reichard, John F; Futscher, Bernard W; Lantz, R Clark 2011. Arsenic toxicology: translating between experimental models and human pathology. Environmental health perspectives, 119 10, 1356-63Reichard, John F; Puga, Alvaro 2010. Effects of arsenic exposure on DNA methylation and epigenetic gene regulation. Epigenomics, 2 1, 87-104Reichard, Jonathan D; Prajapati, Suresh I; Austad, Steven N; Keller, Charles; Kunz, Thomas H 2010. Thermal windows on Brazilian free-tailed bats facilitate thermoregulation during prolonged flight. Integrative and comparative biology, 50 3, 358-70Sartor, Maureen A; Schnekenburger, Michael; Marlowe, Jennifer L; Reichard, John F; Wang, Ying; Fan, Yunxia; Ma, Ci; Karyala, Saikumar; Halbleib, Danielle; Liu, Xiangdong; Medvedovic, Mario; Puga, Alvaro 2009. Genomewide analysis of aryl hydrocarbon receptor binding targets reveals an extensive array of gene clusters that control morphogenetic and developmental programs. Environmental health perspectives, 117 7, 1139-46Reichard, John F; Sartor, Maureen A; Puga, Alvaro 2008. BACH1 is a specific repressor of HMOX1 that is inactivated by arsenite. The Journal of biological chemistry, 283 33, 22363-70Reichard, John F; Motz, Gregory T; Puga, Alvaro 2007. Heme oxygenase-1 induction by NRF2 requires inactivation of the transcriptional repressor BACH1. Nucleic acids research, 35 21, 7074-86Reichard, John F; Schnekenburger, Michael; Puga, Alvaro 2007. Long term low-dose arsenic exposure induces loss of DNA methylation. Biochemical and biophysical research communications, 352 1, 188-92Reichard, John F; Petersen, Dennis R 2006. Involvement of phosphatidylinositol 3-kinase and extracellular-regulated kinase in hepatic stellate cell antioxidant response and myofibroblastic transdifferentiation. Archives of biochemistry and biophysics, 446 2, 111-8Kann, Simone; Estes, Cameron; Reichard, John F; Huang, Ming-Ya; Sartor, Maureen A; Schwemberger, Sandy; Chen, Ying; Dalton, Timothy P; Shertzer, Howard G; Xia, Ying; Puga, Alvaro 2005. Butylhydroquinone protects cells genetically deficient in glutathione biosynthesis from arsenite-induced apoptosis without significantly changing their prooxidant status. Toxicological sciences : an official journal of the Society of Toxicology, 87 2, 365-84Kann, Simone; Huang, Ming-Ya; Estes, Cameron; Reichard, John F; Sartor, Maureen A; Xia, Ying; Puga, Alvaro 2005. Arsenite-induced aryl hydrocarbon receptor nuclear translocation results in additive induction of phase I genes and synergistic induction of phase II genes. Molecular pharmacology, 68 2, 336-46Reichard, John F; Dalton, Timothy P; Shertzer, Howard G; Puga, Alvaro 2005. Induction of oxidative stress responses by dioxin and other ligands of the aryl hydrocarbon receptor. Dose-response : a publication of International Hormesis Society, 3 3, 306-31Reichard, John F; Petersen, Dennis R 2004. Hepatic stellate cells lack AP-1 responsiveness to electrophiles and phorbol 12-myristate-13-acetate. Biochemical and biophysical research communications, 322 3, 842-53Reichard, John F; Doorn, Jonathan A; Simon, Franz; Taylor, Melinda S; Petersen, Dennis R 2003. Characterization of multidrug resistance-associated protein 2 in the hepatocellular disposition of 4-hydroxynonenal. Archives of biochemistry and biophysics, 411 2, 243-50Reichard, J F; Vasiliou, V; Petersen, D R 2000. Characterization of 4-hydroxy-2-nonenal metabolism in stellate cell lines derived from normal and cirrhotic rat liver. Biochimica et biophysica acta, 1487 2-3, 222-32Hartley, D P; Kolaja, K L; Reichard, J; Petersen, D R 1999. 4-Hydroxynonenal and malondialdehyde hepatic protein adducts in rats treated with carbon tetrachloride: immunochemical detection and lobular localization. Toxicology and applied pharmacology, 161 1, 23-33 Plante I.; Daniels V.; Young M.; Gaza R.; Wu H.; Reichard J.F. 12-01-2025. The long-term stability of solid-state oral pharmaceuticals exposed to simulated intravehicular spac Npj Microgravity, 11 1, Reichard J.F.; Phelps S.E.; Lehnhardt K.R.; Young M.; Easter B.D. 12-01-2023. The effect of long-term spaceflight on drug potency and the risk of medication failure Npj Microgravity, 9 1, Reichard J.; Puga A. 08-08-2012. Epigenetic Histone Changes in the Toxicologic Mode of Action of Arsenic Toxicology and Epigenetics, , 339-356 Reichard J.F.; Barned S.; Mendy A.; Pinney S.M. 08-01-2025. Radon Exposure to the General Population of the Fernald Community Cohort Atmosphere, 16 8, Obariase E.; Reichard J.F. 03-01-2026. Dissolution of Inorganic Lead (Pb) in Synthetic Sweat: Implications for Dermal Exposure and Occupati Toxics, 14 3, Brawley H.N.; Reichard J.F.; Shennara K.; Lovett D.; Babcock L.; MacDonald A.; Easter B.; Soares M.; Mateus J.; Rosenberg M.; Nowadly C. 01-01-2026. Comparative Analysis of Pharmaceutical Content Following Spaceflight and Vacuum Exposure During Comm Wilderness and Environmental Medicine, , Massarsky A.; Evans V.J.B.; Fung E.S.; Yang L.G.L.; Rogers K.L.; Buerger A.N.; Maier A.; Reichard J.F. 01-01-2026. A framework for assessing the safety of degraded pharmaceuticals for long-duration space missions - Critical Reviews in Toxicology, , Massarsky A.; Evans V.J.B.; Fung E.S.; Yang L.G.L.; Rogers K.L.; Buerger A.N.; Maier A.; Reichard J.F. 01-01-2026. A framework for assessing the safety of degraded pharmaceuticals for long-duration space missions - Critical Reviews in Toxicology, ,
Brawley, Hayley N; Reichard, John F; Shennara, Khaled; Lovett, Dennis; Babcock, Lyle; MacDonald, Austin; Easter, Benjamin; Soares, Michael; Mateus, Jaime; Rosenberg, Marissa; Nowadly, Craig 2026. Comparative Analysis of Pharmaceutical Content Following Spaceflight and Vacuum Exposure During Commercial Extravehicular Activity. Wilderness & environmental medicine, , 10806032261426910Brawley, Hayley N; Reichard, John F; Shennara, Khaled; Lovett, Dennis; Babcock, Lyle; MacDonald, Austin; Easter, Benjamin; Soares, Michael; Mateus, Jaime; Rosenberg, Marissa; Nowadly, Craig 2026. Comparative Analysis of Pharmaceutical Content Following Spaceflight and Vacuum Exposure During Commercial Extravehicular Activity. Wilderness & environmental medicine, , 10806032261426910Massarsky, Andrey; Evans, Veneese J B; Fung, Ernest S; Yang, Lisa G L; Rogers, Keegan L; Buerger, Amanda N; Maier, Andrew; Reichard, John F 2026. A framework for assessing the safety of degraded pharmaceuticals for long-duration space missions - Part 1: framework development. Critical reviews in toxicology, , 1-34Massarsky, Andrey; Evans, Veneese J B; Fung, Ernest S; Yang, Lisa G L; Rogers, Keegan L; Buerger, Amanda N; Maier, Andrew; Reichard, John F 2026. A framework for assessing the safety of degraded pharmaceuticals for long-duration space missions - Part 1: framework development. Critical reviews in toxicology, , 1-34Obariase, Efosa; Reichard, John F 2026. Dissolution of Inorganic Lead (Pb) in Synthetic Sweat: Implications for Dermal Exposure and Occupational Risk. Toxics, 14 3, Obariase, Efosa; Reichard, John F 2026. Dissolution of Inorganic Lead (Pb) in Synthetic Sweat: Implications for Dermal Exposure and Occupational Risk. Toxics, 14 3, Plante, Ianik; Daniels, Vernie; Young, Millennia; Gaza, Ramona; Wu, Honglu; Reichard, John F 2025. The long-term stability of solid-state oral pharmaceuticals exposed to simulated intravehicular space radiation. NPJ microgravity, 11 1, 17Plante, Ianik; Daniels, Vernie; Young, Millennia; Gaza, Ramona; Wu, Honglu; Reichard, John F 2025. The long-term stability of solid-state oral pharmaceuticals exposed to simulated intravehicular space radiation. NPJ microgravity, 11 1, 17Reichard, John F; Barned, Swade; Mendy, Angelico; Pinney, Susan M 2025. Radon Exposure to the General Population of the Fernald Community Cohort. Atmosphere, 16 8, Reichard, John F; Barned, Swade; Mendy, Angelico; Pinney, Susan M 2025. Radon Exposure to the General Population of the Fernald Community Cohort. Atmosphere, 16 8, Reichard, Julia; Wolff, Philip; Xie, Song; Zuo, Ke; Fullio, Camila L; Du, Jian; Graff, Severin; Linde, Jenice; Yildiz, Can Bora; Pitschelatow, Georg; Nabbefeld, Gerion; Dorp, Lilli; Vollmer, Johanna; Biemans, Linda; Kempf, Shirley; Singh, Minali; Mohan, K Naga; Kuo, Chao-Chung; Vogel, Tanja; Carloni, Paolo; Musall, Simon; Zimmer-Bensch, Geraldine 2025. DNMT1-mediated regulation of somatostatin-positive interneuron migration impacts cortical architecture and function. Nature communications, 16 1, 6834Reichard, Julia; Wolff, Philip; Xie, Song; Zuo, Ke; Fullio, Camila L; Du, Jian; Graff, Severin; Linde, Jenice; Yildiz, Can Bora; Pitschelatow, Georg; Nabbefeld, Gerion; Dorp, Lilli; Vollmer, Johanna; Biemans, Linda; Kempf, Shirley; Singh, Minali; Mohan, K Naga; Kuo, Chao-Chung; Vogel, Tanja; Carloni, Paolo; Musall, Simon; Zimmer-Bensch, Geraldine 2025. DNMT1-mediated regulation of somatostatin-positive interneuron migration impacts cortical architecture and function. Nature communications, 16 1, 6834Udell, Bradley J; Stratton, Christian; Irvine, Kathryn M; Straw, Bethany Rose; Reichard, Jonathan D; Gaulke, Sarah; Coleman, Jeremy T H; Tousley, Frank C; Schuhmann, Andrea N; Inman, Richard D; Turner, Melinda; Nystrom, Sarah; Reichert, Brian E 2025. Integrated distribution modeling resolves asynchrony between bat population impacts and occupancy trends through latent abundance. Communications biology, 8 1, 832Udell, Bradley J; Stratton, Christian; Irvine, Kathryn M; Straw, Bethany Rose; Reichard, Jonathan D; Gaulke, Sarah; Coleman, Jeremy T H; Tousley, Frank C; Schuhmann, Andrea N; Inman, Richard D; Turner, Melinda; Nystrom, Sarah; Reichert, Brian E 2025. Integrated distribution modeling resolves asynchrony between bat population impacts and occupancy trends through latent abundance. Communications biology, 8 1, 832Niang, Mamadou; Reponen, Tiina; Talaska, Glenn; Ying, Jun; Reichard, John F; Pecquet, Alison; Maier, Andrew 2024. Preliminary human health risk assessment of antibiotic exposures in human waste handling occupations. Journal of occupational and environmental hygiene, 21 10, 721-740El-Khoury, Bashir B; Ray, Kristi L; Altchuler, Steven I; Reichard, John F; Dukes, Charles H 2023. Selective Serotonin Reuptake Inhibitors and Other Treatment Modalities for Deep Space Missions. Aerospace medicine and human performance, 94 11, 843-851Niang, Mamadou; Reichard, John F; Maier, Andrew; Talaska, Glenn; Ying, Jun; Santo Domingo, Jorge; Varughese, Eunice; Boczek, Laura; Huff, Emma; Reponen, Tiina 2023. Ciprofloxacin- and azithromycin-resistant bacteria in a wastewater treatment plant. Journal of occupational and environmental hygiene, 20 5-6, 219-225Reichard, J F; Phelps, S E; Lehnhardt, K R; Young, M; Easter, B D 2023. The effect of long-term spaceflight on drug potency and the risk of medication failure. NPJ microgravity, 9 1, 35Jolly, Robert A; Bandara, Suren; Bercu, Joel; Callis, Courtney M; Dolan, David G; Graham, Jessica; HaMai, Diem; Barle, Ester Lovsin; Maier, Andrew; Masuda-Herrera, Melisa; Moudgal, Chandrika; Parker, Jillian A; Reichard, John; Sandhu, Reena; Fung, Ernest S 2022. Setting impurity limits for endogenous substances: Recommendations for a harmonized procedure and an example using fatty acids. Regulatory toxicology and pharmacology : RTP, 134 , 105242Niemeier, Richard Todd; Maier, Andrew; Reichard, John F 2022. Rapid Review of Dermal Penetration and Absorption of Inorganic Lead Compounds for Occupational Risk Assessment. Annals of work exposures and health, 66 3, 291-311Pilarczyk, Marcin; Fazel-Najafabadi, Mehdi; Kouril, Michal; Shamsaei, Behrouz; Vasiliauskas, Juozas; Niu, Wen; Mahi, Naim; Zhang, Lixia; Clark, Nicholas A; Ren, Yan; White, Shana; Karim, Rashid; Xu, Huan; Biesiada, Jacek; Bennett, Mark F; Davidson, Sarah E; Reichard, John F; Roberts, Kurt; Stathias, Vasileios; Koleti, Amar; Vidovic, Dusica; Clarke, Daniel J B; Schürer, Stephan C; Ma'ayan, Avi; Meller, Jarek; Medvedovic, Mario 2022. Connecting omics signatures and revealing biological mechanisms with iLINCS. Nature communications, 13 1, 4678Haber, Lynne T; Reichard, John F; Henning, Alice K; Dawson, Peter; Chinthrajah, R Sharon; Sindher, Sayantani B; Long, Andrew; Vincent, Melissa J; Nadeau, Kari C; Allen, Bruce C 2021. Bayesian hierarchical evaluation of dose-response for peanut allergy in clinical trial screening. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 151 , 112125Ishau, Simileoluwa; Reichard, John F; Maier, Andrew; Niang, Mamadou; Yermakov, Michael; Grinshpun, Sergey A 2020. Estimated dermal exposure to nebulized pharmaceuticals for a simulated home healthcare worker scenario. Journal of occupational and environmental hygiene, 17 4, 193-205Juarez, Paul D; Tabatabai, Mohammad; Valdez, Robert Burciaga; Hood, Darryl B; Im, Wansoo; Mouton, Charles; Colen, Cynthia; Al-Hamdan, Mohammad Z; Matthews-Juarez, Patricia; Lichtveld, Maureen Y; Sarpong, Daniel; Ramesh, Aramandla; Langston, Michael A; Rogers, Gary L; Phillips, Charles A; Reichard, John F; Donneyong, Macarius M; Blot, William 2020. The Effects of Social, Personal, and Behavioral Risk Factors and PM2.5 on Cardio-Metabolic Disparities in a Cohort of Community Health Center Patients. International journal of environmental research and public health, 17 10, Symmank, Judit; Bayer, Cathrin; Reichard, Julia; Pensold, Daniel; Zimmer-Bensch, Geraldine 2020. Neuronal Lhx1 expression is regulated by DNMT1-dependent modulation of histone marks. Epigenetics, 15 11, 1259-1274Cifuentes, Patricia; Reichard, John; Im, Wansoo; Smith, Sakima; Colen, Cynthia; Giurgescu, Carmen; Williams, Karen Patricia; Gillespie, Shannon; Juarez, Paul D; Hood, Darryl B 2019. Application of the Public Health Exposome Framework to Estimate Phenotypes of Resilience in a Model Ohio African-American Women's Cohort. Journal of urban health : bulletin of the New York Academy of Medicine, 96 Suppl 1, 57-71Frank, Evan; Ishau, Simileoluwa; Maier, Andrew; Reutman, Susan; Reichard, John F 2019. An occupational exposure limit (OEL) approach to protect home healthcare workers exposed to common nebulized drugs. Regulatory toxicology and pharmacology : RTP, 106 , 251-261Keenan, Alexandra B; Jenkins, Sherry L; Jagodnik, Kathleen M; Koplev, Simon; He, Edward; Torre, Denis; Wang, Zichen; Dohlman, Anders B; Silverstein, Moshe C; Lachmann, Alexander; Kuleshov, Maxim V; Ma'ayan, Avi; Stathias, Vasileios; Terryn, Raymond; Cooper, Daniel; Forlin, Michele; Koleti, Amar; Vidovic, Dusica; Chung, Caty; Schürer, Stephan C; Vasiliauskas, Jouzas; Pilarczyk, Marcin; Shamsaei, Behrouz; Fazel, Mehdi; Ren, Yan; Niu, Wen; Clark, Nicholas A; White, Shana; Mahi, Naim; Zhang, Lixia; Kouril, Michal; Reichard, John F; Sivaganesan, Siva; Medvedovic, Mario; Meller, Jaroslaw; Koch, Rick J; Birtwistle, Marc R; Iyengar, Ravi; Sobie, Eric A; Azeloglu, Evren U; Kaye, Julia; Osterloh, Jeannette; Haston, Kelly; Kalra, Jaslin; Finkbiener, Steve; Li, Jonathan; Milani, Pamela; Adam, Miriam; Escalante-Chong, Renan; Sachs, Karen; Lenail, Alex; Ramamoorthy, Divya; Fraenkel, Ernest; Daigle, Gavin; Hussain, Uzma; Coye, Alyssa; Rothstein, Jeffrey; Sareen, Dhruv; Ornelas, Loren; Banuelos, Maria; Mandefro, Berhan; Ho, Ritchie; Svendsen, Clive N; Lim, Ryan G; Stocksdale, Jennifer; Casale, Malcolm S; Thompson, Terri G; Wu, Jie; Thompson, Leslie M; Dardov, Victoria; Venkatraman, Vidya; Matlock, Andrea; Van Eyk, Jennifer E; Jaffe, Jacob D; Papanastasiou, Malvina; Subramanian, Aravind; Golub, Todd R; Erickson, Sean D; Fallahi-Sichani, Mohammad; Hafner, Marc; Gray, Nathanael S; Lin, Jia-Ren; Mills, Caitlin E; Muhlich, Jeremy L; Niepel, Mario; Shamu, Caroline E; Williams, Elizabeth H; Wrobel, David; Sorger, Peter K; Heiser, Laura M; Gray, Joe W; Korkola, James E; Mills, Gordon B; LaBarge, Mark; Feiler, Heidi S; Dane, Mark A; Bucher, Elmar; Nederlof, Michel; Sudar, Damir; Gross, Sean; Kilburn, David F; Smith, Rebecca; Devlin, Kaylyn; Margolis, Ron; Derr, Leslie; Lee, Albert; Pillai, Ajay 2018. The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations. Cell systems, 6 1, 13-24Dourson, Michael L; Higginbotham, Jeri; Crum, Jeff; Burleigh-Flayer, Heather; Nance, Patricia; Forsberg, Norman D; Lafranconi, Mark; Reichard, John 2017. Update: Mode of action (MOA) for liver tumors induced by oral exposure to 1,4-dioxane. Regulatory toxicology and pharmacology : RTP, 88 , 45-55Reichard, John F; Haber, Lynne T 2016. Mode-of-action evaluation for the effect of trans fatty acids on low-density lipoprotein cholesterol. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 98 Pt B, 282-294Reichard, John F; Maier, M Andrew; Naumann, Bruce D; Pecquet, Alison M; Pfister, Thomas; Sandhu, Reena; Sargent, Edward V; Streeter, Anthony J; Weideman, Patricia A 2016. Toxicokinetic and toxicodynamic considerations when deriving health-based exposure limits for pharmaceuticals. Regulatory toxicology and pharmacology : RTP, 79 Suppl 1 , S67-78Budinsky, R A; Schrenk, D; Simon, T; Van den Berg, M; Reichard, J F; Silkworth, J B; Aylward, L L; Brix, A; Gasiewicz, T; Kaminski, N; Perdew, G; Starr, T B; Walker, N J; Rowlands, J C 2014. Mode of action and dose-response framework analysis for receptor-mediated toxicity: The aryl hydrocarbon receptor as a case study. Critical reviews in toxicology, 44 1, 83-119Dourson, Michael; Reichard, John; Nance, Patricia; Burleigh-Flayer, Heather; Parker, Ann; Vincent, Melissa; McConnell, Ernest E 2014. Mode of action analysis for liver tumors from oral 1,4-dioxane exposures and evidence-based dose response assessment. Regulatory toxicology and pharmacology : RTP, 68 3, 387-401Chen, Jing; Hu, Zhen; Phatak, Mukta; Reichard, John; Freudenberg, Johannes M; Sivaganesan, Siva; Medvedovic, Mario 2013. Genome-wide signatures of transcription factor activity: connecting transcription factors, disease, and small molecules. PLoS computational biology, 9 9, e1003198Muñoz-Garcia, Agustí; Ro, Jennifer; Reichard, Jonathan D; Kunz, Thomas H; Williams, Joseph B 2012. Cutaneous water loss and lipids of the stratum corneum in two syntopic species of bats. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 161 2, 208-15States, J Christopher; Barchowsky, Aaron; Cartwright, Iain L; Reichard, John F; Futscher, Bernard W; Lantz, R Clark 2011. Arsenic toxicology: translating between experimental models and human pathology. Environmental health perspectives, 119 10, 1356-63Reichard, John F; Puga, Alvaro 2010. Effects of arsenic exposure on DNA methylation and epigenetic gene regulation. Epigenomics, 2 1, 87-104Reichard, Jonathan D; Prajapati, Suresh I; Austad, Steven N; Keller, Charles; Kunz, Thomas H 2010. Thermal windows on Brazilian free-tailed bats facilitate thermoregulation during prolonged flight. Integrative and comparative biology, 50 3, 358-70Sartor, Maureen A; Schnekenburger, Michael; Marlowe, Jennifer L; Reichard, John F; Wang, Ying; Fan, Yunxia; Ma, Ci; Karyala, Saikumar; Halbleib, Danielle; Liu, Xiangdong; Medvedovic, Mario; Puga, Alvaro 2009. Genomewide analysis of aryl hydrocarbon receptor binding targets reveals an extensive array of gene clusters that control morphogenetic and developmental programs. Environmental health perspectives, 117 7, 1139-46Reichard, John F; Sartor, Maureen A; Puga, Alvaro 2008. BACH1 is a specific repressor of HMOX1 that is inactivated by arsenite. The Journal of biological chemistry, 283 33, 22363-70Reichard, John F; Motz, Gregory T; Puga, Alvaro 2007. Heme oxygenase-1 induction by NRF2 requires inactivation of the transcriptional repressor BACH1. Nucleic acids research, 35 21, 7074-86Reichard, John F; Schnekenburger, Michael; Puga, Alvaro 2007. Long term low-dose arsenic exposure induces loss of DNA methylation. Biochemical and biophysical research communications, 352 1, 188-92Reichard, John F; Petersen, Dennis R 2006. Involvement of phosphatidylinositol 3-kinase and extracellular-regulated kinase in hepatic stellate cell antioxidant response and myofibroblastic transdifferentiation. Archives of biochemistry and biophysics, 446 2, 111-8Kann, Simone; Estes, Cameron; Reichard, John F; Huang, Ming-Ya; Sartor, Maureen A; Schwemberger, Sandy; Chen, Ying; Dalton, Timothy P; Shertzer, Howard G; Xia, Ying; Puga, Alvaro 2005. Butylhydroquinone protects cells genetically deficient in glutathione biosynthesis from arsenite-induced apoptosis without significantly changing their prooxidant status. Toxicological sciences : an official journal of the Society of Toxicology, 87 2, 365-84Kann, Simone; Huang, Ming-Ya; Estes, Cameron; Reichard, John F; Sartor, Maureen A; Xia, Ying; Puga, Alvaro 2005. Arsenite-induced aryl hydrocarbon receptor nuclear translocation results in additive induction of phase I genes and synergistic induction of phase II genes. Molecular pharmacology, 68 2, 336-46Reichard, John F; Dalton, Timothy P; Shertzer, Howard G; Puga, Alvaro 2005. Induction of oxidative stress responses by dioxin and other ligands of the aryl hydrocarbon receptor. Dose-response : a publication of International Hormesis Society, 3 3, 306-31Reichard, John F; Petersen, Dennis R 2004. Hepatic stellate cells lack AP-1 responsiveness to electrophiles and phorbol 12-myristate-13-acetate. Biochemical and biophysical research communications, 322 3, 842-53Reichard, John F; Doorn, Jonathan A; Simon, Franz; Taylor, Melinda S; Petersen, Dennis R 2003. Characterization of multidrug resistance-associated protein 2 in the hepatocellular disposition of 4-hydroxynonenal. Archives of biochemistry and biophysics, 411 2, 243-50Reichard, J F; Vasiliou, V; Petersen, D R 2000. Characterization of 4-hydroxy-2-nonenal metabolism in stellate cell lines derived from normal and cirrhotic rat liver. Biochimica et biophysica acta, 1487 2-3, 222-32Hartley, D P; Kolaja, K L; Reichard, J; Petersen, D R 1999. 4-Hydroxynonenal and malondialdehyde hepatic protein adducts in rats treated with carbon tetrachloride: immunochemical detection and lobular localization. Toxicology and applied pharmacology, 161 1, 23-33 Plante I.; Daniels V.; Young M.; Gaza R.; Wu H.; Reichard J.F. 12-01-2025. The long-term stability of solid-state oral pharmaceuticals exposed to simulated intravehicular spac Npj Microgravity, 11 1, Reichard J.F.; Phelps S.E.; Lehnhardt K.R.; Young M.; Easter B.D. 12-01-2023. The effect of long-term spaceflight on drug potency and the risk of medication failure Npj Microgravity, 9 1, Reichard J.; Puga A. 08-08-2012. Epigenetic Histone Changes in the Toxicologic Mode of Action of Arsenic Toxicology and Epigenetics, , 339-356 Reichard J.F.; Barned S.; Mendy A.; Pinney S.M. 08-01-2025. Radon Exposure to the General Population of the Fernald Community Cohort Atmosphere, 16 8, Obariase E.; Reichard J.F. 03-01-2026. Dissolution of Inorganic Lead (Pb) in Synthetic Sweat: Implications for Dermal Exposure and Occupati Toxics, 14 3, Brawley H.N.; Reichard J.F.; Shennara K.; Lovett D.; Babcock L.; MacDonald A.; Easter B.; Soares M.; Mateus J.; Rosenberg M.; Nowadly C. 01-01-2026. Comparative Analysis of Pharmaceutical Content Following Spaceflight and Vacuum Exposure During Comm Wilderness and Environmental Medicine, , Massarsky A.; Evans V.J.B.; Fung E.S.; Yang L.G.L.; Rogers K.L.; Buerger A.N.; Maier A.; Reichard J.F. 01-01-2026. 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