Contact Information Childrens Hospital Bldg R Office 513-636-4200 Email lutzkocm@ucmail.uc.edu Peer Reviewed Publications Rubinstein, Jeremy D; Jodele, Sonata; Heyenbruch, Daria; Wilhelm, Jamie; Thomas, Shawn; Lutzko, Carolyn; Zhu, Xiang; Leemhuis, Thomas; Cancelas, Jose A; Keller, Michael; Bollard, Catherine M; Hanley, Patrick J; Boghdadly, Zeinab El; Mims, Alice; Davies, Stella M; Grimley, Michael S; Nelson, Adam S 2022. Off-the-Shelf Third-Party Virus-Specific T Cell Therapy to Treat JC Polyomavirus Infection in Hematopoietic Stem Cell Transplantation Recipients. Transplantation and cellular therapy, 28 2, 116.e1-116.e7Rubinstein, Jeremy D; Lutzko, Carolyn; Leemhuis, Thomas; Zhu, Xiang; Pham, Giang; Ray, Lorraine; Thomas, Shawn; Dourson, Celeste; Wilhelm, Jamie; Lane, Adam; Cancelas, Jose A; Lipps, Dakota; Ferrell, Justin; Hanley, Patrick J; Keller, Michael D; Bollard, Catherine M; Wang, YunZu M; Davies, Stella M; Nelson, Adam S; Grimley, Michael S 2022. Scheduled administration of virus-specific T cells for viral prophylaxis after pediatric allogeneic stem cell transplant. Blood advances, 6 9, 2897-2907Rubinstein, Jeremy D; Zhu, Xiang; Leemhuis, Thomas; Pham, Giang; Ray, Lorraine; Emberesh, Sana; Jodele, Sonata; Thomas, Shawn; Cancelas, Jose A; Bollard, Catherine M; Hanley, Patrick J; Keller, Michael D; Grimley, Olivia; Clark, Diana; Clark, Teri; Lindestam Arlehamn, Cecilia S; Sette, Alessandro; Davies, Stella M; Nelson, Adam S; Grimley, Michael S; Lutzko, Carolyn 2021. Virus-specific T cells for adenovirus infection after stem cell transplantation are highly effective and class II HLA restricted. Blood advances, 5 17, 3309-3321Khandelwal, Pooja; Chaturvedi, Vijaya; Owsley, Erika; Lane, Adam; Heyenbruch, Daria; Lutzko, Carolyn M; Leemhuis, Thomas; Grimley, Michael S; Nelson, Adam S; Davies, Stella M; Jordan, Michael B; Marsh, Rebecca A 2020. CD38brightCD8+ T Cells Associated with the Development of Acute GVHD Are Activated, Proliferating, and Cytotoxic Trafficking Cells. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 26 1, 1-6Laskin, Benjamin L; Denburg, Michelle R; Furth, Susan L; Moatz, Taylor; Altrich, Michelle; Kleiboeker, Steve; Lutzko, Carolyn; Zhu, Xiang; Blackard, Jason T; Jodele, Sonata; Lane, Adam; Wallace, Gregory; Dandoy, Christopher E; Lake, Kelly; Duell, Alexandra; Litts, Bridget; Seif, Alix E; Olson, Timothy; Bunin, Nancy; Davies, Stella M 2020. The Natural History of BK Polyomavirus and the Host Immune Response After Stem Cell Transplantation. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 71 12, 3044-3054Muench, David E; Olsson, Andre; Ferchen, Kyle; Pham, Giang; Serafin, Rachel A; Chutipongtanate, Somchai; Dwivedi, Pankaj; Song, Baobao; Hay, Stuart; Chetal, Kashish; Trump-Durbin, Lisa R; Mookerjee-Basu, Jayati; Zhang, Kejian; Yu, Jennifer C; Lutzko, Carolyn; Myers, Kasiani C; Nazor, Kristopher L; Greis, Kenneth D; Kappes, Dietmar J; Way, Sing Sing; Salomonis, Nathan; Grimes, H Leighton 2020. Mouse models of neutropenia reveal progenitor-stage-specific defects. Nature, 582 7810, 109-114Nelson, Adam S; Heyenbruch, Daria; Rubinstein, Jeremy D; Sabulski, Anthony; Jodele, Sonata; Thomas, Shawn; Lutzko, Carolyn; Zhu, Xiang; Leemhuis, Thomas; Cancelas, Jose A; Keller, Michael; Bollard, Catherine M; Hanley, Patrick J; Davies, Stella M; Grimley, Michael S 2020. Virus-specific T-cell therapy to treat BK polyomavirus infection in bone marrow and solid organ transplant recipients. Blood advances, 4 22, 5745-5754Rubinstein, Jeremy D; Burns, Karen; Absalon, Michael; Lutzko, Carolyn; Leemhuis, Tom; Chandra, Sharat; Hanley, Patrick J; Keller, Michael D; Davies, Stella M; Nelson, Adam; Grimley, Michael 2020. EBV-directed viral-specific T-lymphocyte therapy for the treatment of EBV-driven lymphoma in two patients with primary immunodeficiency and DNA repair defects. Pediatric blood & cancer, 67 3, e28126Rubinstein, Jeremy D; Zhu, Xiang; Lutzko, Carolyn; Leemhuis, Tom; Cancelas, Jose A; Jodele, Sonata; Bollard, Catherine M; Hanley, Patrick J; Davies, Stella M; Grimley, Michael S; Nelson, Adam S 2020. Complement inhibition does not impair the clinical antiviral capabilities of virus-specific T-cell therapy. Blood advances, 4 14, 3252-3257Seu, Katie G; Trump, Lisa R; Emberesh, Sana; Lorsbach, Robert B; Johnson, Clarissa; Meznarich, Jessica; Underhill, Hunter R; Chou, Stella T; Sakthivel, Haripriya; Nassar, Nicolas N; Seu, Kalani J; Blanc, Lionel; Zhang, Wenying; Lutzko, Carolyn M; Kalfa, Theodosia A 2020. VPS4A Mutations in Humans Cause Syndromic Congenital Dyserythropoietic Anemia due to Cytokinesis and Trafficking Defects. American journal of human genetics, 107 6, 1149-1156Trump, Lisa R; Nayak, Ramesh C; Singh, Abhishek K; Emberesh, Sana; Wellendorf, Ashley M; Lutzko, Carolyn M; Cancelas, Jose A 2019. Neutrophils Derived from Genetically Modified Human Induced Pluripotent Stem Cells Circulate and Phagocytose Bacteria In Vivo. Stem cells translational medicine, 8 6, 557-567Daily, Kenneth; Ho Sui, Shannan J; Schriml, Lynn M; Dexheimer, Phillip J; Salomonis, Nathan; Schroll, Robin; Bush, Stacy; Keddache, Mehdi; Mayhew, Christopher; Lotia, Samad; Perumal, Thanneer M; Dang, Kristen; Pantano, Lorena; Pico, Alexander R; Grassman, Elke; Nordling, Diana; Hide, Winston; Hatzopoulos, Antonis K; Malik, Punam; Cancelas, Jose A; Lutzko, Carolyn; Aronow, Bruce J; Omberg, Larsson 2017. Molecular, phenotypic, and sample-associated data to describe pluripotent stem cell lines and derivatives. Scientific data, 4 , 170030Nasimuzzaman, Md; Lynn, Danielle; Ernst, Rebecca; Beuerlein, Michele; Smith, Richard H; Shrestha, Archana; Cross, Scott; Link, Kevin; Lutzko, Carolyn; Nordling, Diana; Russell, David W; Larochelle, Andre; Malik, Punam; Van der Loo, Johannes C M 2016. Production and purification of high-titer foamy virus vector for the treatment of leukocyte adhesion deficiency. Molecular therapy. Methods & clinical development, 3 , 16004Salomonis, Nathan; Dexheimer, Phillip J; Omberg, Larsson; Schroll, Robin; Bush, Stacy; Huo, Jeffrey; Schriml, Lynn; Ho Sui, Shannan; Keddache, Mehdi; Mayhew, Christopher; Shanmukhappa, Shiva Kumar; Wells, James; Daily, Kenneth; Hubler, Shane; Wang, Yuliang; Zambidis, Elias; Margolin, Adam; Hide, Winston; Hatzopoulos, Antonis K; Malik, Punam; Cancelas, Jose A; Aronow, Bruce J; Lutzko, Carolyn 2016. Integrated Genomic Analysis of Diverse Induced Pluripotent Stem Cells from the Progenitor Cell Biology Consortium. Stem cell reports, 7 1, 110-25Nayak, Ramesh C; Trump, Lisa R; Aronow, Bruce J; Myers, Kasiani; Mehta, Parinda; Kalfa, Theodosia; Wellendorf, Ashley M; Valencia, C Alexander; Paddison, Patrick J; Horwitz, Marshall S; Grimes, H Leighton; Lutzko, Carolyn; Cancelas, Jose A 2015. Pathogenesis of ELANE-mutant severe neutropenia revealed by induced pluripotent stem cells. The Journal of clinical investigation, 125 8, 3103-16Suzuki, Takuji; Arumugam, Paritha; Sakagami, Takuro; Lachmann, Nico; Chalk, Claudia; Sallese, Anthony; Abe, Shuichi; Trapnell, Cole; Carey, Brenna; Moritz, Thomas; Malik, Punam; Lutzko, Carolyn; Wood, Robert E; Trapnell, Bruce C 2014. Pulmonary macrophage transplantation therapy. Nature, 514 7523, 450-4Tidwell, Timothy; Wechsler, Jeremy; Nayak, Ramesh C; Trump, Lisa; Salipante, Stephen J; Cheng, Jerry C; Donadieu, Jean; Glaubach, Taly; Corey, Seth J; Grimes, H Leighton; Lutzko, Carolyn; Cancelas, Jose A; Horwitz, Marshall S 2014. Neutropenia-associated ELANE mutations disrupting translation initiation produce novel neutrophil elastase isoforms. Blood, 123 4, 562-9Tsai, Steven C; Chang, David F; Hong, Chang-Mu; Xia, Ping; Senadheera, Dinithi; Trump, Lisa; Mishra, Suparna; Lutzko, Carolyn 2014. Induced overexpression of OCT4A in human embryonic stem cells increases cloning efficiency. American journal of physiology. Cell physiology, 306 12, C1108-18Weiss, Daniel J; Bates, Jason H T; Gilbert, Thomas; Liles, W Conrad; Lutzko, Carolyn; Rajagopal, Jay; Prockop, Darwin 2013. Stem cells and cell therapies in lung biology and diseases: conference report. Annals of the American Thoracic Society, 10 5, S25-44Chen, Leiling; Acciani, Thomas; Le Cras, Tim; Lutzko, Carolyn; Perl, Anne-Karina T 2012. Dynamic regulation of platelet-derived growth factor receptor ? expression in alveolar fibroblasts during realveolarization. American journal of respiratory cell and molecular biology, 47 4, 517-27Hasegawa, Kouichi; Yasuda, Shin-ya; Teo, Jia-Ling; Nguyen, Cu; McMillan, Michael; Hsieh, Chih-Lin; Suemori, Hirofumi; Nakatsuji, Norio; Yamamoto, Masashi; Miyabayashi, Tomoyuki; Lutzko, Carolyn; Pera, Martin F; Kahn, Michael 2012. Wnt signaling orchestration with a small molecule DYRK inhibitor provides long-term xeno-free human pluripotent cell expansion. Stem cells translational medicine, 1 1, 18-28Mishra, Suparna; Wang, Xingchao; Smiley, Nancy; Xia, Ping; Hong, Chang Mu; Senadheera, Dinithi; Bui, Kim Chi; Lutzko, Carolyn 2011. Genetic modification of airway progenitors after lentiviral gene delivery to the amniotic fluid of murine fetuses. American journal of respiratory cell and molecular biology, 44 4, 562-70Bui, Kim Chi T; Senadheera, Dinithi; Wang, Xingchao; Hendrickson, Benjamin; Friedlich, Philippe; Lutzko, Carolyn 2010. Recovery of multipotent progenitors from the peripheral blood of patients requiring extracorporeal membrane oxygenation support. American journal of respiratory and critical care medicine, 181 3, 226-37Chang, David F; Tsai, Steven C; Wang, Xing Chao; Xia, Ping; Senadheera, Dinithi; Lutzko, Carolyn 2009. Molecular characterization of the human NANOG protein. Stem cells (Dayton, Ohio), 27 4, 812-21Harb, Rula; Xie, Guanhua; Lutzko, Carolyn; Guo, Yumei; Wang, Xiangdong; Hill, Colin K; Kanel, Gary C; DeLeve, Laurie D 2009. Bone marrow progenitor cells repair rat hepatic sinusoidal endothelial cells after liver injury. Gastroenterology, 137 2, 704-12Jiang, Xiaohua; Gwye, Ynnez; McKeown, Sonja J; Bronner-Fraser, Marianne; Lutzko, Carolyn; Lawlor, Elizabeth R 2009. Isolation and characterization of neural crest stem cells derived from in vitro-differentiated human embryonic stem cells. Stem cells and development, 18 7, 1059-70Liebler, Janice M; Lutzko, Carolyn; Banfalvi, Agnes; Senadheera, Dinithi; Aghamohammadi, Neema; Crandall, Edward D; Borok, Zea 2008. Retention of human bone marrow-derived cells in murine lungs following bleomycin-induced lung injury. American journal of physiology. Lung cellular and molecular physiology, 295 2, L285-92Melchior, Kai; Weiss, Jonathan; Zaehres, Holm; Kim, Yong-mi; Lutzko, Carolyn; Roosta, Neda; Hescheler, Jürgen; Müschen, Markus 2008. The WNT receptor FZD7 contributes to self-renewal signaling of human embryonic stem cells. Biological chemistry, 389 7, 897-903Hendrickson, Benjamin; Senadheera, Dinithi; Mishra, Suparna; Bui, Kim Chi T; Wang, Xingchao; Chan, Belinda; Petersen, Denise; Pepper, Karen; Lutzko, Carolyn 2007. Development of lentiviral vectors with regulated respiratory epithelial expression in vivo. American journal of respiratory cell and molecular biology, 37 4, 414-23Rodriguez, Ryan T; Velkey, J Matthew; Lutzko, Carolyn; Seerke, Rina; Kohn, Donald B; O'Shea, K Sue; Firpo, Meri T 2007. Manipulation of OCT4 levels in human embryonic stem cells results in induction of differential cell types. Experimental biology and medicine (Maywood, N.J.), 232 10, 1368-80Jang, Jung-Eun; Shaw, Kit; Yu, Xiao-Jin; Petersen, Denise; Pepper, Karen; Lutzko, Carolyn; Kohn, Donald B 2006. Specific and stable gene transfer to human embryonic stem cells using pseudotyped lentiviral vectors. Stem cells and development, 15 1, 109-17Jodele, Sonata; Chantrain, Christophe F; Blavier, Laurence; Lutzko, Carolyn; Crooks, Gay M; Shimada, Hiroyuki; Coussens, Lisa M; Declerck, Yves A 2005. The contribution of bone marrow-derived cells to the tumor vasculature in neuroblastoma is matrix metalloproteinase-9 dependent. Cancer research, 65 8, 3200-8Sesti, Casilde; Hale, Sharon L; Lutzko, Carolyn; Kloner, Robert A 2005. Granulocyte colony-stimulating factor and stem cell factor improve contractile reserve of the infarcted left ventricle independent of restoring muscle mass. Journal of the American College of Cardiology, 46 9, 1662-9Tarantal, Alice F; McDonald, Ruth J; Jimenez, Daniel F; Lee, C Chang I; O'Shea, Cristin E; Leapley, Alyssa C; Won, Rosa H; Plopper, Charles G; Lutzko, Carolyn; Kohn, Donald B 2005. Intrapulmonary and intramyocardial gene transfer in rhesus monkeys (Macaca mulatta): safety and efficiency of HIV-1-derived lentiviral vectors for fetal gene delivery. Molecular therapy : the journal of the American Society of Gene Therapy, 12 1, 87-98Haas, Dennis L; Lutzko, Carolyn; Logan, Aaron C; Cho, Gerald J; Skelton, Dianne; Jin Yu, Xiao; Pepper, Karen A; Kohn, Donald B 2003. The Moloney murine leukemia virus repressor binding site represses expression in murine and human hematopoietic stem cells. Journal of virology, 77 17, 9439-50Lutzko, Carolyn; Senadheera, Dinithi; Skelton, Dianne; Petersen, Denise; Kohn, Donald B 2003. Lentivirus vectors incorporating the immunoglobulin heavy chain enhancer and matrix attachment regions provide position-independent expression in B lymphocytes. Journal of virology, 77 13, 7341-51Grove, Joanna E; Lutzko, Carolyn; Priller, Josef; Henegariu, Octavian; Theise, Neil D; Kohn, Donald B; Krause, Diane S 2002. Marrow-derived cells as vehicles for delivery of gene therapy to pulmonary epithelium. American journal of respiratory cell and molecular biology, 27 6, 645-51Logan, Aaron C; Lutzko, Carolyn; Kohn, Donald B 2002. Advances in lentiviral vector design for gene-modification of hematopoietic stem cells. Current opinion in biotechnology, 13 5, 429-36Lutzko, Carolyn; Meertens, Lisa; Li, Liheng; Zhao, Yongjun; Abrams-Ogg, Anthony; Woods, J Paul; Kruth, Stephen; Hough, Margaret R; Dubé, Ian D 2002. Human hematopoietic progenitors engraft in fetal canine recipients and expand with neonatal injection of fibroblasts expressing human hematopoietic cytokines. Experimental hematology, 30 7, 801-8Meertens, Lisa; Zhao, Yongjun; Rosic-Kablar, Suzana; Li, Liheng; Chan, Kin; Dobson, Howard; Gartley, Cathy; Lutzko, Carolyn; Hopwood, John; Kohn, Donald; Kruth, Stephen; Hough, Margaret R; Dubé, Ian D 2002. In utero injection of alpha-L-iduronidase-carrying retrovirus in canine mucopolysaccharidosis type I: infection of multiple tissues and neonatal gene expression. Human gene therapy, 13 15, 1809-20Lutzko, CAROLYN; Abrams-Ogg, ANTHONY C. G.; Li, LIHENG; Zhao, YONGJUN; Lau, KATHY; Kruth, STEPHEN; Dubé, IAN D. 2000. BMT: Fractionation of Gene Modified Hematopoietic Autografts into Multiple Weekly Infusions Does Not Improve Engraftment in Unconditioned Canine Recipients. Hematology (Amsterdam, Netherlands), 4 6, 499-503
Peer Reviewed Publications Rubinstein, Jeremy D; Jodele, Sonata; Heyenbruch, Daria; Wilhelm, Jamie; Thomas, Shawn; Lutzko, Carolyn; Zhu, Xiang; Leemhuis, Thomas; Cancelas, Jose A; Keller, Michael; Bollard, Catherine M; Hanley, Patrick J; Boghdadly, Zeinab El; Mims, Alice; Davies, Stella M; Grimley, Michael S; Nelson, Adam S 2022. Off-the-Shelf Third-Party Virus-Specific T Cell Therapy to Treat JC Polyomavirus Infection in Hematopoietic Stem Cell Transplantation Recipients. Transplantation and cellular therapy, 28 2, 116.e1-116.e7Rubinstein, Jeremy D; Lutzko, Carolyn; Leemhuis, Thomas; Zhu, Xiang; Pham, Giang; Ray, Lorraine; Thomas, Shawn; Dourson, Celeste; Wilhelm, Jamie; Lane, Adam; Cancelas, Jose A; Lipps, Dakota; Ferrell, Justin; Hanley, Patrick J; Keller, Michael D; Bollard, Catherine M; Wang, YunZu M; Davies, Stella M; Nelson, Adam S; Grimley, Michael S 2022. Scheduled administration of virus-specific T cells for viral prophylaxis after pediatric allogeneic stem cell transplant. Blood advances, 6 9, 2897-2907Rubinstein, Jeremy D; Zhu, Xiang; Leemhuis, Thomas; Pham, Giang; Ray, Lorraine; Emberesh, Sana; Jodele, Sonata; Thomas, Shawn; Cancelas, Jose A; Bollard, Catherine M; Hanley, Patrick J; Keller, Michael D; Grimley, Olivia; Clark, Diana; Clark, Teri; Lindestam Arlehamn, Cecilia S; Sette, Alessandro; Davies, Stella M; Nelson, Adam S; Grimley, Michael S; Lutzko, Carolyn 2021. Virus-specific T cells for adenovirus infection after stem cell transplantation are highly effective and class II HLA restricted. Blood advances, 5 17, 3309-3321Khandelwal, Pooja; Chaturvedi, Vijaya; Owsley, Erika; Lane, Adam; Heyenbruch, Daria; Lutzko, Carolyn M; Leemhuis, Thomas; Grimley, Michael S; Nelson, Adam S; Davies, Stella M; Jordan, Michael B; Marsh, Rebecca A 2020. CD38brightCD8+ T Cells Associated with the Development of Acute GVHD Are Activated, Proliferating, and Cytotoxic Trafficking Cells. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 26 1, 1-6Laskin, Benjamin L; Denburg, Michelle R; Furth, Susan L; Moatz, Taylor; Altrich, Michelle; Kleiboeker, Steve; Lutzko, Carolyn; Zhu, Xiang; Blackard, Jason T; Jodele, Sonata; Lane, Adam; Wallace, Gregory; Dandoy, Christopher E; Lake, Kelly; Duell, Alexandra; Litts, Bridget; Seif, Alix E; Olson, Timothy; Bunin, Nancy; Davies, Stella M 2020. The Natural History of BK Polyomavirus and the Host Immune Response After Stem Cell Transplantation. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 71 12, 3044-3054Muench, David E; Olsson, Andre; Ferchen, Kyle; Pham, Giang; Serafin, Rachel A; Chutipongtanate, Somchai; Dwivedi, Pankaj; Song, Baobao; Hay, Stuart; Chetal, Kashish; Trump-Durbin, Lisa R; Mookerjee-Basu, Jayati; Zhang, Kejian; Yu, Jennifer C; Lutzko, Carolyn; Myers, Kasiani C; Nazor, Kristopher L; Greis, Kenneth D; Kappes, Dietmar J; Way, Sing Sing; Salomonis, Nathan; Grimes, H Leighton 2020. Mouse models of neutropenia reveal progenitor-stage-specific defects. Nature, 582 7810, 109-114Nelson, Adam S; Heyenbruch, Daria; Rubinstein, Jeremy D; Sabulski, Anthony; Jodele, Sonata; Thomas, Shawn; Lutzko, Carolyn; Zhu, Xiang; Leemhuis, Thomas; Cancelas, Jose A; Keller, Michael; Bollard, Catherine M; Hanley, Patrick J; Davies, Stella M; Grimley, Michael S 2020. Virus-specific T-cell therapy to treat BK polyomavirus infection in bone marrow and solid organ transplant recipients. Blood advances, 4 22, 5745-5754Rubinstein, Jeremy D; Burns, Karen; Absalon, Michael; Lutzko, Carolyn; Leemhuis, Tom; Chandra, Sharat; Hanley, Patrick J; Keller, Michael D; Davies, Stella M; Nelson, Adam; Grimley, Michael 2020. EBV-directed viral-specific T-lymphocyte therapy for the treatment of EBV-driven lymphoma in two patients with primary immunodeficiency and DNA repair defects. Pediatric blood & cancer, 67 3, e28126Rubinstein, Jeremy D; Zhu, Xiang; Lutzko, Carolyn; Leemhuis, Tom; Cancelas, Jose A; Jodele, Sonata; Bollard, Catherine M; Hanley, Patrick J; Davies, Stella M; Grimley, Michael S; Nelson, Adam S 2020. Complement inhibition does not impair the clinical antiviral capabilities of virus-specific T-cell therapy. Blood advances, 4 14, 3252-3257Seu, Katie G; Trump, Lisa R; Emberesh, Sana; Lorsbach, Robert B; Johnson, Clarissa; Meznarich, Jessica; Underhill, Hunter R; Chou, Stella T; Sakthivel, Haripriya; Nassar, Nicolas N; Seu, Kalani J; Blanc, Lionel; Zhang, Wenying; Lutzko, Carolyn M; Kalfa, Theodosia A 2020. VPS4A Mutations in Humans Cause Syndromic Congenital Dyserythropoietic Anemia due to Cytokinesis and Trafficking Defects. American journal of human genetics, 107 6, 1149-1156Trump, Lisa R; Nayak, Ramesh C; Singh, Abhishek K; Emberesh, Sana; Wellendorf, Ashley M; Lutzko, Carolyn M; Cancelas, Jose A 2019. Neutrophils Derived from Genetically Modified Human Induced Pluripotent Stem Cells Circulate and Phagocytose Bacteria In Vivo. Stem cells translational medicine, 8 6, 557-567Daily, Kenneth; Ho Sui, Shannan J; Schriml, Lynn M; Dexheimer, Phillip J; Salomonis, Nathan; Schroll, Robin; Bush, Stacy; Keddache, Mehdi; Mayhew, Christopher; Lotia, Samad; Perumal, Thanneer M; Dang, Kristen; Pantano, Lorena; Pico, Alexander R; Grassman, Elke; Nordling, Diana; Hide, Winston; Hatzopoulos, Antonis K; Malik, Punam; Cancelas, Jose A; Lutzko, Carolyn; Aronow, Bruce J; Omberg, Larsson 2017. Molecular, phenotypic, and sample-associated data to describe pluripotent stem cell lines and derivatives. Scientific data, 4 , 170030Nasimuzzaman, Md; Lynn, Danielle; Ernst, Rebecca; Beuerlein, Michele; Smith, Richard H; Shrestha, Archana; Cross, Scott; Link, Kevin; Lutzko, Carolyn; Nordling, Diana; Russell, David W; Larochelle, Andre; Malik, Punam; Van der Loo, Johannes C M 2016. Production and purification of high-titer foamy virus vector for the treatment of leukocyte adhesion deficiency. Molecular therapy. Methods & clinical development, 3 , 16004Salomonis, Nathan; Dexheimer, Phillip J; Omberg, Larsson; Schroll, Robin; Bush, Stacy; Huo, Jeffrey; Schriml, Lynn; Ho Sui, Shannan; Keddache, Mehdi; Mayhew, Christopher; Shanmukhappa, Shiva Kumar; Wells, James; Daily, Kenneth; Hubler, Shane; Wang, Yuliang; Zambidis, Elias; Margolin, Adam; Hide, Winston; Hatzopoulos, Antonis K; Malik, Punam; Cancelas, Jose A; Aronow, Bruce J; Lutzko, Carolyn 2016. Integrated Genomic Analysis of Diverse Induced Pluripotent Stem Cells from the Progenitor Cell Biology Consortium. Stem cell reports, 7 1, 110-25Nayak, Ramesh C; Trump, Lisa R; Aronow, Bruce J; Myers, Kasiani; Mehta, Parinda; Kalfa, Theodosia; Wellendorf, Ashley M; Valencia, C Alexander; Paddison, Patrick J; Horwitz, Marshall S; Grimes, H Leighton; Lutzko, Carolyn; Cancelas, Jose A 2015. Pathogenesis of ELANE-mutant severe neutropenia revealed by induced pluripotent stem cells. The Journal of clinical investigation, 125 8, 3103-16Suzuki, Takuji; Arumugam, Paritha; Sakagami, Takuro; Lachmann, Nico; Chalk, Claudia; Sallese, Anthony; Abe, Shuichi; Trapnell, Cole; Carey, Brenna; Moritz, Thomas; Malik, Punam; Lutzko, Carolyn; Wood, Robert E; Trapnell, Bruce C 2014. Pulmonary macrophage transplantation therapy. Nature, 514 7523, 450-4Tidwell, Timothy; Wechsler, Jeremy; Nayak, Ramesh C; Trump, Lisa; Salipante, Stephen J; Cheng, Jerry C; Donadieu, Jean; Glaubach, Taly; Corey, Seth J; Grimes, H Leighton; Lutzko, Carolyn; Cancelas, Jose A; Horwitz, Marshall S 2014. Neutropenia-associated ELANE mutations disrupting translation initiation produce novel neutrophil elastase isoforms. Blood, 123 4, 562-9Tsai, Steven C; Chang, David F; Hong, Chang-Mu; Xia, Ping; Senadheera, Dinithi; Trump, Lisa; Mishra, Suparna; Lutzko, Carolyn 2014. Induced overexpression of OCT4A in human embryonic stem cells increases cloning efficiency. American journal of physiology. Cell physiology, 306 12, C1108-18Weiss, Daniel J; Bates, Jason H T; Gilbert, Thomas; Liles, W Conrad; Lutzko, Carolyn; Rajagopal, Jay; Prockop, Darwin 2013. Stem cells and cell therapies in lung biology and diseases: conference report. Annals of the American Thoracic Society, 10 5, S25-44Chen, Leiling; Acciani, Thomas; Le Cras, Tim; Lutzko, Carolyn; Perl, Anne-Karina T 2012. Dynamic regulation of platelet-derived growth factor receptor ? expression in alveolar fibroblasts during realveolarization. American journal of respiratory cell and molecular biology, 47 4, 517-27Hasegawa, Kouichi; Yasuda, Shin-ya; Teo, Jia-Ling; Nguyen, Cu; McMillan, Michael; Hsieh, Chih-Lin; Suemori, Hirofumi; Nakatsuji, Norio; Yamamoto, Masashi; Miyabayashi, Tomoyuki; Lutzko, Carolyn; Pera, Martin F; Kahn, Michael 2012. Wnt signaling orchestration with a small molecule DYRK inhibitor provides long-term xeno-free human pluripotent cell expansion. Stem cells translational medicine, 1 1, 18-28Mishra, Suparna; Wang, Xingchao; Smiley, Nancy; Xia, Ping; Hong, Chang Mu; Senadheera, Dinithi; Bui, Kim Chi; Lutzko, Carolyn 2011. Genetic modification of airway progenitors after lentiviral gene delivery to the amniotic fluid of murine fetuses. American journal of respiratory cell and molecular biology, 44 4, 562-70Bui, Kim Chi T; Senadheera, Dinithi; Wang, Xingchao; Hendrickson, Benjamin; Friedlich, Philippe; Lutzko, Carolyn 2010. Recovery of multipotent progenitors from the peripheral blood of patients requiring extracorporeal membrane oxygenation support. American journal of respiratory and critical care medicine, 181 3, 226-37Chang, David F; Tsai, Steven C; Wang, Xing Chao; Xia, Ping; Senadheera, Dinithi; Lutzko, Carolyn 2009. Molecular characterization of the human NANOG protein. Stem cells (Dayton, Ohio), 27 4, 812-21Harb, Rula; Xie, Guanhua; Lutzko, Carolyn; Guo, Yumei; Wang, Xiangdong; Hill, Colin K; Kanel, Gary C; DeLeve, Laurie D 2009. Bone marrow progenitor cells repair rat hepatic sinusoidal endothelial cells after liver injury. Gastroenterology, 137 2, 704-12Jiang, Xiaohua; Gwye, Ynnez; McKeown, Sonja J; Bronner-Fraser, Marianne; Lutzko, Carolyn; Lawlor, Elizabeth R 2009. Isolation and characterization of neural crest stem cells derived from in vitro-differentiated human embryonic stem cells. Stem cells and development, 18 7, 1059-70Liebler, Janice M; Lutzko, Carolyn; Banfalvi, Agnes; Senadheera, Dinithi; Aghamohammadi, Neema; Crandall, Edward D; Borok, Zea 2008. Retention of human bone marrow-derived cells in murine lungs following bleomycin-induced lung injury. American journal of physiology. Lung cellular and molecular physiology, 295 2, L285-92Melchior, Kai; Weiss, Jonathan; Zaehres, Holm; Kim, Yong-mi; Lutzko, Carolyn; Roosta, Neda; Hescheler, Jürgen; Müschen, Markus 2008. The WNT receptor FZD7 contributes to self-renewal signaling of human embryonic stem cells. Biological chemistry, 389 7, 897-903Hendrickson, Benjamin; Senadheera, Dinithi; Mishra, Suparna; Bui, Kim Chi T; Wang, Xingchao; Chan, Belinda; Petersen, Denise; Pepper, Karen; Lutzko, Carolyn 2007. Development of lentiviral vectors with regulated respiratory epithelial expression in vivo. American journal of respiratory cell and molecular biology, 37 4, 414-23Rodriguez, Ryan T; Velkey, J Matthew; Lutzko, Carolyn; Seerke, Rina; Kohn, Donald B; O'Shea, K Sue; Firpo, Meri T 2007. Manipulation of OCT4 levels in human embryonic stem cells results in induction of differential cell types. Experimental biology and medicine (Maywood, N.J.), 232 10, 1368-80Jang, Jung-Eun; Shaw, Kit; Yu, Xiao-Jin; Petersen, Denise; Pepper, Karen; Lutzko, Carolyn; Kohn, Donald B 2006. Specific and stable gene transfer to human embryonic stem cells using pseudotyped lentiviral vectors. Stem cells and development, 15 1, 109-17Jodele, Sonata; Chantrain, Christophe F; Blavier, Laurence; Lutzko, Carolyn; Crooks, Gay M; Shimada, Hiroyuki; Coussens, Lisa M; Declerck, Yves A 2005. The contribution of bone marrow-derived cells to the tumor vasculature in neuroblastoma is matrix metalloproteinase-9 dependent. Cancer research, 65 8, 3200-8Sesti, Casilde; Hale, Sharon L; Lutzko, Carolyn; Kloner, Robert A 2005. Granulocyte colony-stimulating factor and stem cell factor improve contractile reserve of the infarcted left ventricle independent of restoring muscle mass. Journal of the American College of Cardiology, 46 9, 1662-9Tarantal, Alice F; McDonald, Ruth J; Jimenez, Daniel F; Lee, C Chang I; O'Shea, Cristin E; Leapley, Alyssa C; Won, Rosa H; Plopper, Charles G; Lutzko, Carolyn; Kohn, Donald B 2005. Intrapulmonary and intramyocardial gene transfer in rhesus monkeys (Macaca mulatta): safety and efficiency of HIV-1-derived lentiviral vectors for fetal gene delivery. Molecular therapy : the journal of the American Society of Gene Therapy, 12 1, 87-98Haas, Dennis L; Lutzko, Carolyn; Logan, Aaron C; Cho, Gerald J; Skelton, Dianne; Jin Yu, Xiao; Pepper, Karen A; Kohn, Donald B 2003. The Moloney murine leukemia virus repressor binding site represses expression in murine and human hematopoietic stem cells. Journal of virology, 77 17, 9439-50Lutzko, Carolyn; Senadheera, Dinithi; Skelton, Dianne; Petersen, Denise; Kohn, Donald B 2003. Lentivirus vectors incorporating the immunoglobulin heavy chain enhancer and matrix attachment regions provide position-independent expression in B lymphocytes. Journal of virology, 77 13, 7341-51Grove, Joanna E; Lutzko, Carolyn; Priller, Josef; Henegariu, Octavian; Theise, Neil D; Kohn, Donald B; Krause, Diane S 2002. Marrow-derived cells as vehicles for delivery of gene therapy to pulmonary epithelium. American journal of respiratory cell and molecular biology, 27 6, 645-51Logan, Aaron C; Lutzko, Carolyn; Kohn, Donald B 2002. Advances in lentiviral vector design for gene-modification of hematopoietic stem cells. Current opinion in biotechnology, 13 5, 429-36Lutzko, Carolyn; Meertens, Lisa; Li, Liheng; Zhao, Yongjun; Abrams-Ogg, Anthony; Woods, J Paul; Kruth, Stephen; Hough, Margaret R; Dubé, Ian D 2002. Human hematopoietic progenitors engraft in fetal canine recipients and expand with neonatal injection of fibroblasts expressing human hematopoietic cytokines. Experimental hematology, 30 7, 801-8Meertens, Lisa; Zhao, Yongjun; Rosic-Kablar, Suzana; Li, Liheng; Chan, Kin; Dobson, Howard; Gartley, Cathy; Lutzko, Carolyn; Hopwood, John; Kohn, Donald; Kruth, Stephen; Hough, Margaret R; Dubé, Ian D 2002. In utero injection of alpha-L-iduronidase-carrying retrovirus in canine mucopolysaccharidosis type I: infection of multiple tissues and neonatal gene expression. Human gene therapy, 13 15, 1809-20Lutzko, CAROLYN; Abrams-Ogg, ANTHONY C. G.; Li, LIHENG; Zhao, YONGJUN; Lau, KATHY; Kruth, STEPHEN; Dubé, IAN D. 2000. BMT: Fractionation of Gene Modified Hematopoietic Autografts into Multiple Weekly Infusions Does Not Improve Engraftment in Unconditioned Canine Recipients. Hematology (Amsterdam, Netherlands), 4 6, 499-503
Rubinstein, Jeremy D; Jodele, Sonata; Heyenbruch, Daria; Wilhelm, Jamie; Thomas, Shawn; Lutzko, Carolyn; Zhu, Xiang; Leemhuis, Thomas; Cancelas, Jose A; Keller, Michael; Bollard, Catherine M; Hanley, Patrick J; Boghdadly, Zeinab El; Mims, Alice; Davies, Stella M; Grimley, Michael S; Nelson, Adam S 2022. Off-the-Shelf Third-Party Virus-Specific T Cell Therapy to Treat JC Polyomavirus Infection in Hematopoietic Stem Cell Transplantation Recipients. Transplantation and cellular therapy, 28 2, 116.e1-116.e7Rubinstein, Jeremy D; Lutzko, Carolyn; Leemhuis, Thomas; Zhu, Xiang; Pham, Giang; Ray, Lorraine; Thomas, Shawn; Dourson, Celeste; Wilhelm, Jamie; Lane, Adam; Cancelas, Jose A; Lipps, Dakota; Ferrell, Justin; Hanley, Patrick J; Keller, Michael D; Bollard, Catherine M; Wang, YunZu M; Davies, Stella M; Nelson, Adam S; Grimley, Michael S 2022. Scheduled administration of virus-specific T cells for viral prophylaxis after pediatric allogeneic stem cell transplant. Blood advances, 6 9, 2897-2907Rubinstein, Jeremy D; Zhu, Xiang; Leemhuis, Thomas; Pham, Giang; Ray, Lorraine; Emberesh, Sana; Jodele, Sonata; Thomas, Shawn; Cancelas, Jose A; Bollard, Catherine M; Hanley, Patrick J; Keller, Michael D; Grimley, Olivia; Clark, Diana; Clark, Teri; Lindestam Arlehamn, Cecilia S; Sette, Alessandro; Davies, Stella M; Nelson, Adam S; Grimley, Michael S; Lutzko, Carolyn 2021. Virus-specific T cells for adenovirus infection after stem cell transplantation are highly effective and class II HLA restricted. Blood advances, 5 17, 3309-3321Khandelwal, Pooja; Chaturvedi, Vijaya; Owsley, Erika; Lane, Adam; Heyenbruch, Daria; Lutzko, Carolyn M; Leemhuis, Thomas; Grimley, Michael S; Nelson, Adam S; Davies, Stella M; Jordan, Michael B; Marsh, Rebecca A 2020. CD38brightCD8+ T Cells Associated with the Development of Acute GVHD Are Activated, Proliferating, and Cytotoxic Trafficking Cells. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 26 1, 1-6Laskin, Benjamin L; Denburg, Michelle R; Furth, Susan L; Moatz, Taylor; Altrich, Michelle; Kleiboeker, Steve; Lutzko, Carolyn; Zhu, Xiang; Blackard, Jason T; Jodele, Sonata; Lane, Adam; Wallace, Gregory; Dandoy, Christopher E; Lake, Kelly; Duell, Alexandra; Litts, Bridget; Seif, Alix E; Olson, Timothy; Bunin, Nancy; Davies, Stella M 2020. The Natural History of BK Polyomavirus and the Host Immune Response After Stem Cell Transplantation. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 71 12, 3044-3054Muench, David E; Olsson, Andre; Ferchen, Kyle; Pham, Giang; Serafin, Rachel A; Chutipongtanate, Somchai; Dwivedi, Pankaj; Song, Baobao; Hay, Stuart; Chetal, Kashish; Trump-Durbin, Lisa R; Mookerjee-Basu, Jayati; Zhang, Kejian; Yu, Jennifer C; Lutzko, Carolyn; Myers, Kasiani C; Nazor, Kristopher L; Greis, Kenneth D; Kappes, Dietmar J; Way, Sing Sing; Salomonis, Nathan; Grimes, H Leighton 2020. Mouse models of neutropenia reveal progenitor-stage-specific defects. Nature, 582 7810, 109-114Nelson, Adam S; Heyenbruch, Daria; Rubinstein, Jeremy D; Sabulski, Anthony; Jodele, Sonata; Thomas, Shawn; Lutzko, Carolyn; Zhu, Xiang; Leemhuis, Thomas; Cancelas, Jose A; Keller, Michael; Bollard, Catherine M; Hanley, Patrick J; Davies, Stella M; Grimley, Michael S 2020. Virus-specific T-cell therapy to treat BK polyomavirus infection in bone marrow and solid organ transplant recipients. Blood advances, 4 22, 5745-5754Rubinstein, Jeremy D; Burns, Karen; Absalon, Michael; Lutzko, Carolyn; Leemhuis, Tom; Chandra, Sharat; Hanley, Patrick J; Keller, Michael D; Davies, Stella M; Nelson, Adam; Grimley, Michael 2020. EBV-directed viral-specific T-lymphocyte therapy for the treatment of EBV-driven lymphoma in two patients with primary immunodeficiency and DNA repair defects. Pediatric blood & cancer, 67 3, e28126Rubinstein, Jeremy D; Zhu, Xiang; Lutzko, Carolyn; Leemhuis, Tom; Cancelas, Jose A; Jodele, Sonata; Bollard, Catherine M; Hanley, Patrick J; Davies, Stella M; Grimley, Michael S; Nelson, Adam S 2020. Complement inhibition does not impair the clinical antiviral capabilities of virus-specific T-cell therapy. Blood advances, 4 14, 3252-3257Seu, Katie G; Trump, Lisa R; Emberesh, Sana; Lorsbach, Robert B; Johnson, Clarissa; Meznarich, Jessica; Underhill, Hunter R; Chou, Stella T; Sakthivel, Haripriya; Nassar, Nicolas N; Seu, Kalani J; Blanc, Lionel; Zhang, Wenying; Lutzko, Carolyn M; Kalfa, Theodosia A 2020. VPS4A Mutations in Humans Cause Syndromic Congenital Dyserythropoietic Anemia due to Cytokinesis and Trafficking Defects. American journal of human genetics, 107 6, 1149-1156Trump, Lisa R; Nayak, Ramesh C; Singh, Abhishek K; Emberesh, Sana; Wellendorf, Ashley M; Lutzko, Carolyn M; Cancelas, Jose A 2019. Neutrophils Derived from Genetically Modified Human Induced Pluripotent Stem Cells Circulate and Phagocytose Bacteria In Vivo. Stem cells translational medicine, 8 6, 557-567Daily, Kenneth; Ho Sui, Shannan J; Schriml, Lynn M; Dexheimer, Phillip J; Salomonis, Nathan; Schroll, Robin; Bush, Stacy; Keddache, Mehdi; Mayhew, Christopher; Lotia, Samad; Perumal, Thanneer M; Dang, Kristen; Pantano, Lorena; Pico, Alexander R; Grassman, Elke; Nordling, Diana; Hide, Winston; Hatzopoulos, Antonis K; Malik, Punam; Cancelas, Jose A; Lutzko, Carolyn; Aronow, Bruce J; Omberg, Larsson 2017. Molecular, phenotypic, and sample-associated data to describe pluripotent stem cell lines and derivatives. Scientific data, 4 , 170030Nasimuzzaman, Md; Lynn, Danielle; Ernst, Rebecca; Beuerlein, Michele; Smith, Richard H; Shrestha, Archana; Cross, Scott; Link, Kevin; Lutzko, Carolyn; Nordling, Diana; Russell, David W; Larochelle, Andre; Malik, Punam; Van der Loo, Johannes C M 2016. Production and purification of high-titer foamy virus vector for the treatment of leukocyte adhesion deficiency. Molecular therapy. Methods & clinical development, 3 , 16004Salomonis, Nathan; Dexheimer, Phillip J; Omberg, Larsson; Schroll, Robin; Bush, Stacy; Huo, Jeffrey; Schriml, Lynn; Ho Sui, Shannan; Keddache, Mehdi; Mayhew, Christopher; Shanmukhappa, Shiva Kumar; Wells, James; Daily, Kenneth; Hubler, Shane; Wang, Yuliang; Zambidis, Elias; Margolin, Adam; Hide, Winston; Hatzopoulos, Antonis K; Malik, Punam; Cancelas, Jose A; Aronow, Bruce J; Lutzko, Carolyn 2016. Integrated Genomic Analysis of Diverse Induced Pluripotent Stem Cells from the Progenitor Cell Biology Consortium. Stem cell reports, 7 1, 110-25Nayak, Ramesh C; Trump, Lisa R; Aronow, Bruce J; Myers, Kasiani; Mehta, Parinda; Kalfa, Theodosia; Wellendorf, Ashley M; Valencia, C Alexander; Paddison, Patrick J; Horwitz, Marshall S; Grimes, H Leighton; Lutzko, Carolyn; Cancelas, Jose A 2015. Pathogenesis of ELANE-mutant severe neutropenia revealed by induced pluripotent stem cells. The Journal of clinical investigation, 125 8, 3103-16Suzuki, Takuji; Arumugam, Paritha; Sakagami, Takuro; Lachmann, Nico; Chalk, Claudia; Sallese, Anthony; Abe, Shuichi; Trapnell, Cole; Carey, Brenna; Moritz, Thomas; Malik, Punam; Lutzko, Carolyn; Wood, Robert E; Trapnell, Bruce C 2014. Pulmonary macrophage transplantation therapy. Nature, 514 7523, 450-4Tidwell, Timothy; Wechsler, Jeremy; Nayak, Ramesh C; Trump, Lisa; Salipante, Stephen J; Cheng, Jerry C; Donadieu, Jean; Glaubach, Taly; Corey, Seth J; Grimes, H Leighton; Lutzko, Carolyn; Cancelas, Jose A; Horwitz, Marshall S 2014. Neutropenia-associated ELANE mutations disrupting translation initiation produce novel neutrophil elastase isoforms. Blood, 123 4, 562-9Tsai, Steven C; Chang, David F; Hong, Chang-Mu; Xia, Ping; Senadheera, Dinithi; Trump, Lisa; Mishra, Suparna; Lutzko, Carolyn 2014. Induced overexpression of OCT4A in human embryonic stem cells increases cloning efficiency. American journal of physiology. Cell physiology, 306 12, C1108-18Weiss, Daniel J; Bates, Jason H T; Gilbert, Thomas; Liles, W Conrad; Lutzko, Carolyn; Rajagopal, Jay; Prockop, Darwin 2013. Stem cells and cell therapies in lung biology and diseases: conference report. Annals of the American Thoracic Society, 10 5, S25-44Chen, Leiling; Acciani, Thomas; Le Cras, Tim; Lutzko, Carolyn; Perl, Anne-Karina T 2012. Dynamic regulation of platelet-derived growth factor receptor ? expression in alveolar fibroblasts during realveolarization. American journal of respiratory cell and molecular biology, 47 4, 517-27Hasegawa, Kouichi; Yasuda, Shin-ya; Teo, Jia-Ling; Nguyen, Cu; McMillan, Michael; Hsieh, Chih-Lin; Suemori, Hirofumi; Nakatsuji, Norio; Yamamoto, Masashi; Miyabayashi, Tomoyuki; Lutzko, Carolyn; Pera, Martin F; Kahn, Michael 2012. Wnt signaling orchestration with a small molecule DYRK inhibitor provides long-term xeno-free human pluripotent cell expansion. Stem cells translational medicine, 1 1, 18-28Mishra, Suparna; Wang, Xingchao; Smiley, Nancy; Xia, Ping; Hong, Chang Mu; Senadheera, Dinithi; Bui, Kim Chi; Lutzko, Carolyn 2011. Genetic modification of airway progenitors after lentiviral gene delivery to the amniotic fluid of murine fetuses. American journal of respiratory cell and molecular biology, 44 4, 562-70Bui, Kim Chi T; Senadheera, Dinithi; Wang, Xingchao; Hendrickson, Benjamin; Friedlich, Philippe; Lutzko, Carolyn 2010. Recovery of multipotent progenitors from the peripheral blood of patients requiring extracorporeal membrane oxygenation support. American journal of respiratory and critical care medicine, 181 3, 226-37Chang, David F; Tsai, Steven C; Wang, Xing Chao; Xia, Ping; Senadheera, Dinithi; Lutzko, Carolyn 2009. Molecular characterization of the human NANOG protein. Stem cells (Dayton, Ohio), 27 4, 812-21Harb, Rula; Xie, Guanhua; Lutzko, Carolyn; Guo, Yumei; Wang, Xiangdong; Hill, Colin K; Kanel, Gary C; DeLeve, Laurie D 2009. Bone marrow progenitor cells repair rat hepatic sinusoidal endothelial cells after liver injury. Gastroenterology, 137 2, 704-12Jiang, Xiaohua; Gwye, Ynnez; McKeown, Sonja J; Bronner-Fraser, Marianne; Lutzko, Carolyn; Lawlor, Elizabeth R 2009. Isolation and characterization of neural crest stem cells derived from in vitro-differentiated human embryonic stem cells. Stem cells and development, 18 7, 1059-70Liebler, Janice M; Lutzko, Carolyn; Banfalvi, Agnes; Senadheera, Dinithi; Aghamohammadi, Neema; Crandall, Edward D; Borok, Zea 2008. Retention of human bone marrow-derived cells in murine lungs following bleomycin-induced lung injury. American journal of physiology. Lung cellular and molecular physiology, 295 2, L285-92Melchior, Kai; Weiss, Jonathan; Zaehres, Holm; Kim, Yong-mi; Lutzko, Carolyn; Roosta, Neda; Hescheler, Jürgen; Müschen, Markus 2008. The WNT receptor FZD7 contributes to self-renewal signaling of human embryonic stem cells. Biological chemistry, 389 7, 897-903Hendrickson, Benjamin; Senadheera, Dinithi; Mishra, Suparna; Bui, Kim Chi T; Wang, Xingchao; Chan, Belinda; Petersen, Denise; Pepper, Karen; Lutzko, Carolyn 2007. Development of lentiviral vectors with regulated respiratory epithelial expression in vivo. American journal of respiratory cell and molecular biology, 37 4, 414-23Rodriguez, Ryan T; Velkey, J Matthew; Lutzko, Carolyn; Seerke, Rina; Kohn, Donald B; O'Shea, K Sue; Firpo, Meri T 2007. Manipulation of OCT4 levels in human embryonic stem cells results in induction of differential cell types. Experimental biology and medicine (Maywood, N.J.), 232 10, 1368-80Jang, Jung-Eun; Shaw, Kit; Yu, Xiao-Jin; Petersen, Denise; Pepper, Karen; Lutzko, Carolyn; Kohn, Donald B 2006. Specific and stable gene transfer to human embryonic stem cells using pseudotyped lentiviral vectors. Stem cells and development, 15 1, 109-17Jodele, Sonata; Chantrain, Christophe F; Blavier, Laurence; Lutzko, Carolyn; Crooks, Gay M; Shimada, Hiroyuki; Coussens, Lisa M; Declerck, Yves A 2005. The contribution of bone marrow-derived cells to the tumor vasculature in neuroblastoma is matrix metalloproteinase-9 dependent. Cancer research, 65 8, 3200-8Sesti, Casilde; Hale, Sharon L; Lutzko, Carolyn; Kloner, Robert A 2005. Granulocyte colony-stimulating factor and stem cell factor improve contractile reserve of the infarcted left ventricle independent of restoring muscle mass. Journal of the American College of Cardiology, 46 9, 1662-9Tarantal, Alice F; McDonald, Ruth J; Jimenez, Daniel F; Lee, C Chang I; O'Shea, Cristin E; Leapley, Alyssa C; Won, Rosa H; Plopper, Charles G; Lutzko, Carolyn; Kohn, Donald B 2005. Intrapulmonary and intramyocardial gene transfer in rhesus monkeys (Macaca mulatta): safety and efficiency of HIV-1-derived lentiviral vectors for fetal gene delivery. Molecular therapy : the journal of the American Society of Gene Therapy, 12 1, 87-98Haas, Dennis L; Lutzko, Carolyn; Logan, Aaron C; Cho, Gerald J; Skelton, Dianne; Jin Yu, Xiao; Pepper, Karen A; Kohn, Donald B 2003. The Moloney murine leukemia virus repressor binding site represses expression in murine and human hematopoietic stem cells. Journal of virology, 77 17, 9439-50Lutzko, Carolyn; Senadheera, Dinithi; Skelton, Dianne; Petersen, Denise; Kohn, Donald B 2003. Lentivirus vectors incorporating the immunoglobulin heavy chain enhancer and matrix attachment regions provide position-independent expression in B lymphocytes. Journal of virology, 77 13, 7341-51Grove, Joanna E; Lutzko, Carolyn; Priller, Josef; Henegariu, Octavian; Theise, Neil D; Kohn, Donald B; Krause, Diane S 2002. Marrow-derived cells as vehicles for delivery of gene therapy to pulmonary epithelium. American journal of respiratory cell and molecular biology, 27 6, 645-51Logan, Aaron C; Lutzko, Carolyn; Kohn, Donald B 2002. Advances in lentiviral vector design for gene-modification of hematopoietic stem cells. Current opinion in biotechnology, 13 5, 429-36Lutzko, Carolyn; Meertens, Lisa; Li, Liheng; Zhao, Yongjun; Abrams-Ogg, Anthony; Woods, J Paul; Kruth, Stephen; Hough, Margaret R; Dubé, Ian D 2002. Human hematopoietic progenitors engraft in fetal canine recipients and expand with neonatal injection of fibroblasts expressing human hematopoietic cytokines. Experimental hematology, 30 7, 801-8Meertens, Lisa; Zhao, Yongjun; Rosic-Kablar, Suzana; Li, Liheng; Chan, Kin; Dobson, Howard; Gartley, Cathy; Lutzko, Carolyn; Hopwood, John; Kohn, Donald; Kruth, Stephen; Hough, Margaret R; Dubé, Ian D 2002. In utero injection of alpha-L-iduronidase-carrying retrovirus in canine mucopolysaccharidosis type I: infection of multiple tissues and neonatal gene expression. Human gene therapy, 13 15, 1809-20Lutzko, CAROLYN; Abrams-Ogg, ANTHONY C. G.; Li, LIHENG; Zhao, YONGJUN; Lau, KATHY; Kruth, STEPHEN; Dubé, IAN D. 2000. BMT: Fractionation of Gene Modified Hematopoietic Autografts into Multiple Weekly Infusions Does Not Improve Engraftment in Unconditioned Canine Recipients. Hematology (Amsterdam, Netherlands), 4 6, 499-503