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Christian Hong, PhD

Associate Professor

Pharmacology & Systems Physiology | College of Medicine

  • PhD: Virginia Tech (Mathematical Modeling)
  • MS: Virginia Tech (Mathematical Modeling)
  • BS: Virginia Tech (Biology)
Contact Information

Peer Reviewed Publications

Caicedo-Casso, Angélica; Kang, Hye-Won; Lim, Sookkyung; Hong, Christian I 2015. Robustness and period sensitivity analysis of minimal models for biochemical oscillators. Scientific reports, 5 , 13161

Chen, Shuang; Brunskill, Eric W; Potter, S Steven; Dexheimer, Phillip J; Salomonis, Nathan; Aronow, Bruce J; Hong, Christian I; Zhang, Tongli; Kopan, Raphael 2015. Intrinsic Age-Dependent Changes and Cell-Cell Contacts Regulate Nephron Progenitor Lifespan. Developmental cell, 35 1, 49-62

Cockrell, Allison L; Pirlo, Russell K; Babson, David M; Cusick, Kathleen D; Soto, Carissa M; Petersen, Emily R; Davis, Miah J; Hong, Christian I; Lee, Kwangwon; Fitzgerald, Lisa A; Biffinger, Justin C 2015. Suppressing the Neurospora crassa circadian clock while maintaining light responsiveness in continuous stirred tank reactors. Scientific reports, 5 , 10691

Dovzhenok, Andrey A; Baek, Mokryun; Lim, Sookkyung; Hong, Christian I 2015. Mathematical modeling and validation of glucose compensation of the neurospora circadian clock. Biophysical journal, 108 7, 1830-9

Hong, Christian I; Zámborszky, Judit; Baek, Mokryun; Labiscsak, Laszlo; Ju, Kyungsu; Lee, Hyeyeong; Larrondo, Luis F; Goity, Alejandra; Chong, Hin Siong; Belden, William J; Csikász-Nagy, Attila 2014. Circadian rhythms synchronize mitosis in Neurospora crassa. Proceedings of the National Academy of Sciences of the United States of America, 111 4, 1397-402

Moore, Sean R; Pruszka, Jill; Vallance, Jefferson; Aihara, Eitaro; Matsuura, Toru; Montrose, Marshall H; Shroyer, Noah F; Hong, Christian I 2014. Robust circadian rhythms in organoid cultures from PERIOD2::LUCIFERASE mouse small intestine. Disease models & mechanisms, 7 9, 1123-30

Zámborszky, Judit; Csikász-Nagy, Attila; Hong, Christian I 2014. Neurospora crassa as a model organism to explore the interconnected network of the cell cycle and the circadian clock. Fungal genetics and biology : FG & B, 71 , 52-7

Lee, Kang Kug; Ahn, Chong H; Hong, Christian I 2013. Circadian rhythms in Neurospora crassa on a polydimethylsiloxane microfluidic device for real-time gas perturbations. Biomicrofluidics, 7 4, 44129

Hong, Christian I; Zámborszky, Judit; Csikász-Nagy, Attila 2009. Minimum criteria for DNA damage-induced phase advances in circadian rhythms. PLoS computational biology, 5 5, e1000384

Hong, Christian I; Jolma, Ingunn W; Loros, Jennifer J; Dunlap, Jay C; Ruoff, Peter 2008. Simulating dark expressions and interactions of frq and wc-1 in the Neurospora circadian clock. Biophysical journal, 94 4, 1221-32

Dunlap, J C; Loros, J J; Colot, H V; Mehra, A; Belden, W J; Shi, M; Hong, C I; Larrondo, L F; Baker, C L; Chen, C-H; Schwerdtfeger, C; Collopy, P D; Gamsby, J J; Lambreghts, R 2007. A circadian clock in Neurospora: how genes and proteins cooperate to produce a sustained, entrainable, and compensated biological oscillator with a period of about a day. Cold Spring Harbor symposia on quantitative biology, 72 , 57-68

Hong, Christian I; Conrad, Emery D; Tyson, John J 2007. A proposal for robust temperature compensation of circadian rhythms. Proceedings of the National Academy of Sciences of the United States of America, 104 4, 1195-200

Loros, J J; Dunlap, J C; Larrondo, L F; Shi, M; Belden, W J; Gooch, V D; Chen, C-H; Baker, C L; Mehra, A; Colot, H V; Schwerdtfeger, C; Lambreghts, R; Collopy, P D; Gamsby, J J; Hong, C I 2007. Circadian output, input, and intracellular oscillators: insights into the circadian systems of single cells. Cold Spring Harbor symposia on quantitative biology, 72 , 201-14

Zámborszky, Judit; Hong, Christian I; Csikász Nagy, Attila 2007. Computational analysis of mammalian cell division gated by a circadian clock: quantized cell cycles and cell size control. Journal of biological rhythms, 22 6, 542-53

Mehra, Arun; Hong, Christian I; Shi, Mi; Loros, Jennifer J; Dunlap, Jay C; Ruoff, Peter 2006. Circadian rhythmicity by autocatalysis. PLoS computational biology, 2 7, e96

Tyson, J J; Hong, C I; Thron, C D; Novak, B 1999. A simple model of circadian rhythms based on dimerization and proteolysis of PER and TIM. Biophysical journal, 77 5, 2411-7