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Photo of  Melinda Butsch Kovacic, MPH, PhD

Melinda Butsch Kovacic, MPH, PhD

Associate Dean

Professor and Associate Dean of Research

Education/Credentials
  • Associates of Science: University of Cincinnati College of Applied Science
  • Bachelors of Science: University of Cincinnati College of Arts and Sciences
  • Doctor of Philosophy: The Ohio State University
  • Masters of Public Health: Harvard University School of Public Health
  • Fellowship: National Cancer Institute
Contact Information

Peer Reviewed Publications

Khoury, Ruby; Sauter, Sharon; Butsch Kovacic, Melinda; Nelson, Adam S; Myers, Kasiani C; Mehta, Parinda A; Davies, Stella M; Wells, Susanne I 2018. Risk of Human Papillomavirus Infection in Cancer-Prone Individuals: What We Know. Viruses, 10 1,

Zhang, Xue; Biagini Myers, Jocelyn M; Burleson, J D; Ulm, Ashley; Bryan, Kelly S; Chen, Xiaoting; Weirauch, Matthew T; Baker, Theresa A; Butsch Kovacic, Melinda S; Ji, Hong 2018. Nasal DNA methylation is associated with childhood asthma. Epigenomics, 10 5, 629-641

Zhao, Xueheng; Brusadelli, Marion G; Sauter, Sharon; Butsch Kovacic, Melinda; Zhang, Wujuan; Romick-Rosendale, Lindsey E; Lambert, Paul F; Setchell, Kenneth D R; Wells, Susanne I 2018. Lipidomic Profiling Links the Fanconi Anemia Pathway to Glycosphingolipid Metabolism in Head and Neck Cancer Cells. Clinical cancer research : an official journal of the American Association for Cancer Research, 24 11, 2700-2709

Hall, Sara L; Baker, Theresa; Lajoie, Stephane; Richgels, Phoebe K; Yang, Yanfen; McAlees, Jaclyn W; van Lier, Adelaide; Wills-Karp, Marsha; Sivaprasad, Umasundari; Acciani, Thomas H; LeCras, Timothy D; Myers, Jocelyn Biagini; Kovacic, Melinda Butsch; Lewkowich, Ian P 2017. IL-17A enhances IL-13 activity by enhancing IL-13-induced signal transducer and activator of transcription 6 activation. The Journal of allergy and clinical immunology, 139 2, 462-471.e14

Mehta, Parinda A; Sauter, Sharon; Zhang, Xue; Davies, Stella M; Wells, Suzanne I; Myers, Kasiani C; Panicker, Gitika; Unger, Elizabeth R; Butsch Kovacic, Melinda 2017. Antibody response to human papillomavirus vaccination and natural exposure in individuals with Fanconi Anemia. Vaccine, 35 48 Pt B, 6712-6719

Myers, Kasiani C; Sauter, Sharon; Zhang, Xue; Bleesing, Jacob J; Davies, Stella M; Wells, Susanne I; Mehta, Parinda A; Kumar, Ashish; Marmer, Daniel; Marsh, Rebecca; Brown, Darron; Butsch Kovacic, Melinda 2017. Impaired immune function in children and adults with Fanconi anemia. Pediatric blood & cancer, 64 11,

Somineni, Hari K; Zhang, Xue; Biagini Myers, Jocelyn M; Kovacic, Melinda Butsch; Ulm, Ashley; Jurcak, Noelle; Ryan, Patrick H; Khurana Hershey, Gurjit K; Ji, Hong 2016. Ten-eleven translocation 1 (TET1) methylation is associated with childhood asthma and traffic-related air pollution. The Journal of allergy and clinical immunology, 137 3, 797-805.e5

Butsch Kovacic, M; Martin, L J; Biagini Myers, J M; He, H; Lindsey, M; Mersha, T B; Khurana Hershey, G K 2015. Genetic approach identifies distinct asthma pathways in overweight vs normal weight children. Allergy, 70 8, 1028-32

Katzenellenbogen, Rachel A; Carter, Joseph J; Stern, Joshua E; Butsch Kovacic, Melinda S; Mehta, Parinda A; Sauter, Sharon L; Galloway, Denise A; Winer, Rachel L 2015. Skin and mucosal human papillomavirus seroprevalence in persons with fanconi anemia. Clinical and vaccine immunology : CVI, 22 4, 413-20

Mersha, Tesfaye B; Martin, Lisa J; Biagini Myers, Jocelyn M; Kovacic, Melinda Butsch; He, Hua; Lindsey, Mark; Sivaprasad, Umasundari; Chen, Weiguo; Khurana Hershey, Gurjit K 2015. Genomic architecture of asthma differs by sex. Genomics, 106 1, 15-22

Sauter, Sharon L; Wells, Susanne I; Zhang, Xue; Hoskins, Elizabeth E; Davies, Stella M; Myers, Kasiani C; Mueller, Robin; Panicker, Gitika; Unger, Elizabeth R; Sivaprasad, Umasundari; Brown, Darron R; Mehta, Parinda A; Butsch Kovacic, Melinda 2015. Oral human papillomavirus is common in individuals with Fanconi anemia. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 24 5, 864-72

Winer, R L; Huang, C E; Cherne, S; Stern, J E; Butsch Kovacic, M S; Mehta, P A; Sauter, S L; Galloway, D A; Katzenellenbogen, R A 2015. Detection of human papillomavirus in the oral cavities of persons with Fanconi anemia. Oral diseases, 21 3, 349-54

Biagini Myers, Jocelyn M; Martin, Lisa J; Kovacic, Melinda Butsch; Mersha, Tesfaye B; He, Hua; Pilipenko, Valentina; Lindsey, Mark A; Ericksen, Mark B; Bernstein, David I; LeMasters, Grace K; Lockey, James E; Khurana Hershey, Gurjit K 2014. Epistasis between serine protease inhibitor Kazal-type 5 (SPINK5) and thymic stromal lymphopoietin (TSLP) genes contributes to childhood asthma. The Journal of allergy and clinical immunology, 134 4, 891-899.e3

Kovacic, Melinda Butsch; Stigler, Sara; Smith, Angela; Kidd, Alexis; Vaughn, Lisa M 2014. Beginning a partnership with PhotoVoice to explore environmental health and health inequities in minority communities. International journal of environmental research and public health, 11 11, 11132-51

Brandt, Eric B; Kovacic, Melinda Butsch; Lee, Gerald B; Gibson, Aaron M; Acciani, Thomas H; Le Cras, Timothy D; Ryan, Patrick H; Budelsky, Alison L; Khurana Hershey, Gurjit K 2013. Diesel exhaust particle induction of IL-17A contributes to severe asthma. The Journal of allergy and clinical immunology, 132 5, 1194-1204.e2

Butsch Kovacic, Melinda; Biagini Myers, Jocelyn M; Lindsey, Mark; Patterson, Tia; Sauter, Sharon; Ericksen, Mark B; Ryan, Patrick; Assa'ad, Amal; Lierl, Michelle; Fischer, Thomas; Kercsmar, Carolyn; McDowell, Karen; Lucky, Anne W; Sheth, Anita P; Hershey, Andrew D; Ruddy, Richard M; Rothenberg, Marc E; Khurana Hershey, Gurjit K 2012. The Greater Cincinnati Pediatric Clinic Repository: A Novel Framework for Childhood Asthma and Allergy Research. Pediatric allergy, immunology, and pulmonology, 25 2, 104-113

Epstein, Tolly G; LeMasters, Grace K; Bernstein, David I; Ericksen, Mark B; Martin, Lisa J; Ryan, Patrick H; Biagini Myers, Jocelyn M; Butsch Kovacic, Melinda S; Lindsey, Mark A; He, Hua; Reponen, Tiina; Villareal, Manuel S; Lockey, James E; Bernstein, Cheryl K; Khurana Hershey, Gurjit K 2012. Genetic variation in small proline rich protein 2B as a predictor for asthma among children with eczema. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 108 3, 145-50

Hoskins, Elizabeth E; Morreale, Richard J; Werner, Stephen P; Higginbotham, Jennifer M; Laimins, Laimonis A; Lambert, Paul F; Brown, Darron R; Gillison, Maura L; Nuovo, Gerard J; Witte, David P; Kim, Mi-Ok; Davies, Stella M; Mehta, Parinda A; Butsch Kovacic, Melinda; Wikenheiser-Brokamp, Kathryn A; Wells, Susanne I 2012. The fanconi anemia pathway limits human papillomavirus replication. Journal of virology, 86 15, 8131-8

Martin, Lisa J; Gupta, Jayanta; Jyothula, Soma S S K; Butsch Kovacic, Melinda; Biagini Myers, Jocelyn M; Patterson, Tia L; Ericksen, Mark B; He, Hua; Gibson, Aaron M; Baye, Tesfaye M; Amirisetty, Sushil; Tsoras, Anna M; Sha, Youbao; Eissa, N Tony; Hershey, Gurjit K Khurana 2012. Functional variant in the autophagy-related 5 gene promotor is associated with childhood asthma. PloS one, 7 4, e33454

Baye, Tesfaye M; Butsch Kovacic, Melinda; Biagini Myers, Jocelyn M; Martin, Lisa J; Lindsey, Mark; Patterson, Tia L; He, Hua; Ericksen, Mark B; Gupta, Jayanta; Tsoras, Anna M; Lindsley, Andrew; Rothenberg, Marc E; Wills-Karp, Marsha; Eissa, N Tony; Borish, Larry; Khurana Hershey, Gurjit K 2011. Differences in candidate gene association between European ancestry and African American asthmatic children. PloS one, 6 2, e16522

Cortina, Sandra D; Drotar, Dennis; Ericksen, Mark; Lindsey, Mark; Patterson, Tia L; Myers, Jocelyn M Biagini; Kovacic, Melinda Butsch; Hershey, Gurjit K Khurana 2011. Genetic biomarkers of health-related quality of life in pediatric asthma. The Journal of pediatrics, 159 1, 21-26.e1

Kovacic, Melinda Butsch; Myers, Jocelyn M Biagini; Wang, Ning; Martin, Lisa J; Lindsey, Mark; Ericksen, Mark B; He, Hua; Patterson, Tia L; Baye, Tesfaye M; Torgerson, Dara; Roth, Lindsey A; Gupta, Jayanta; Sivaprasad, Umasundari; Gibson, Aaron M; Tsoras, Anna M; Hu, Donglei; Eng, Celeste; Chapela, Rocío; Rodríguez-Santana, José R; Rodríguez-Cintrón, William; Avila, Pedro C; Beckman, Kenneth; Seibold, Max A; Gignoux, Chris; Musaad, Salma M; Chen, Weiguo; Burchard, Esteban González; Hershey, Gurjit K Khurana 2011. Identification of KIF3A as a novel candidate gene for childhood asthma using RNA expression and population allelic frequencies differences. PloS one, 6 8, e23714

Myers, Kasiani C; Bleesing, Jack J; Davies, Stella M; Zhang, Xue; Martin, Lisa J; Mueller, Robin; Harris, Richard E; Filipovich, Alexandra H; Kovacic, Melinda B; Wells, Susanne I; Mehta, Parinda A 2011. Impaired immune function in children with Fanconi anaemia. British journal of haematology, 154 2, 234-40

Reszka, Krzysztof J; Sallans, Larry; Macha, Stephen; Brown, Kari; McGraw, Dennis W; Kovacic, Melinda Butsch; Britigan, Bradley E 2011. Airway peroxidases catalyze nitration of the {beta}2-agonist salbutamol and decrease its pharmacological activity. The Journal of pharmacology and experimental therapeutics, 336 2, 440-9

Sherrill, Joseph D; Gao, Pei-Song; Stucke, Emily M; Blanchard, Carine; Collins, Margaret H; Putnam, Phil E; Franciosi, James P; Kushner, Jonathan P; Abonia, J Pablo; Assa'ad, Amal H; Kovacic, Melinda Butsch; Biagini Myers, Jocelyn M; Bochner, Bruce S; He, Hua; Hershey, Gurjit Khurana; Martin, Lisa J; Rothenberg, Marc E 2010. Variants of thymic stromal lymphopoietin and its receptor associate with eosinophilic esophagitis. The Journal of allergy and clinical immunology, 126 1, 160-5.e3

Kovacic, Melinda Butsch; Katki, Hormuzd A; Kreimer, Aimee R; Sherman, Mark E 2008. Epidemiologic analysis of histologic cervical inflammation: relationship to human papillomavirus infections. Human pathology, 39 7, 1088-95

Bolinger, Cheryl; Yilmaz, Alper; Hartman, Tiffiney Roberts; Kovacic, Melinda Butsch; Fernandez, Soledad; Ye, Jianxin; Forget, Mary; Green, Patrick L; Boris-Lawrie, Kathleen 2007. RNA helicase A interacts with divergent lymphotropic retroviruses and promotes translation of human T-cell leukemia virus type 1. Nucleic acids research, 35 8, 2629-42

Gravitt, Patti E; Kovacic, Melinda Butsch; Herrero, Rolando; Schiffman, Mark; Bratti, Concepcion; Hildesheim, Allan; Morales, Jorge; Alfaro, Mario; Sherman, Mark E; Wacholder, Sholom; Rodriguez, Ana-Cecilia; Burk, Robert D 2007. High load for most high risk human papillomavirus genotypes is associated with prevalent cervical cancer precursors but only HPV16 load predicts the development of incident disease. International journal of cancer. Journal international du cancer, 121 12, 2787-93

Kovacic, Melinda Butsch; Castle, Philip E; Herrero, Rolando; Schiffman, Mark; Sherman, Mark E; Wacholder, Sholom; Rodriguez, Ana C; Hutchinson, Martha L; Bratti, M Concepción; Hildesheim, Allan; Morales, Jorge; Alfaro, Mario; Burk, Robert D 2006. Relationships of human papillomavirus type, qualitative viral load, and age with cytologic abnormality. Cancer research, 66 20, 10112-9

Butsch Kovacic, Melinda; Martin, Maureen; Gao, Xiaojiang; Fuksenko, Tatyana; Chen, Chien-Jen; Cheng, Yu-Juen; Chen, Jen-Yang; Apple, Raymond; Hildesheim, Allan; Carrington, Mary 2005. Variation of the killer cell immunoglobulin-like receptors and HLA-C genes in nasopharyngeal carcinoma. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 14 11 Pt 1, 2673-7

Butsch, Melinda; Boris-Lawrie, Kathleen 2002. Destiny of unspliced retroviral RNA: ribosome and/or virion? Journal of virology, 76 7, 3089-94

Butsch, M; Hull, S; Wang, Y; Roberts, T M; Boris-Lawrie, K 1999. The 5' RNA terminus of spleen necrosis virus contains a novel posttranscriptional control element that facilitates human immunodeficiency virus Rev/RRE-independent Gag production. Journal of virology, 73 6, 4847-55

Assa'Ad A.; Biagini Myers J.; Butsch Kovacic M.; Ericksen M.; Fischer T.; Hershey A.; Kercsmar C.; Khurana Hershey G.; Lierl M.; Lindsey M.; Lucky A.; McDowell K.; Patterson T.; Rothenberg M.; Ruddy R.; Ryan P.; Sauter S.; Sheth A. 06-01-2012. The greater cincinnati pediatric clinic repository: A novel framework for childhood asthma and aller Pediatric, Allergy, Immunology, and Pulmonology, 25 2, 104-113

Baker T.; Biagini Myers J.; Butsch Kovacic M.; Kaur D.; Lewkowich I.; Lindsley A.; McAlees J.; McKnight C.; Strait R.; Zhang X. 01-01-2019. Age and early maternal smoking contribute to epithelial cell IL-13 responsiveness in a pediatric ast Allergy: European Journal of Allergy and Clinical Immunology, ,

Bernstein C.; Bernstein D.; Biagini Myers J.; Butsch Kovacic M.; Epstein T.; Ericksen M.; He H.; Khurana Hershey G.; Lemasters G.; Lindsey M.; Lockey J.; Martin L.; Reponen T.; Ryan P.; Villareal M. 01-01-2012. Genetic variation in small proline rich protein 2B as a predictor for asthma among children with ecz Annals of Allergy, Asthma and Immunology, 108 3,