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Photo of  Justin L. Benoit, MD, MS, FAEMS

Justin L. Benoit, MD, MS, FAEMS

Assistant Professor of Clinical

Emergency Medicine | College of Medicine

Education/Credentials
  • Bachelor's Degree: University of Maryland, College Park
  • Master's Degree: University of Cincinnati
  • Medical Degree: Case Western Reserve University
  • Residency: University of Cincinnati
  • Fellowship: University of Cincinnati
Board Certifications & Licenses

American Board of Emergency Medicine (Emergency Medical Services) (Certification Date: 20171117)
American Board of Emergency Medicine (Certification Date: 20151119)

Specialties

Emergency Medicine

Contact Information
Research Interests

Prehospital Medicine
Cardiac Arrest
Emergency Airway Management
Biomarkers

Clinical Interests

Emergency Medicine

Peer Reviewed Publications

Azouz, Nurit P; Klingler, Andrea M; Callahan, Victoria; Akhrymuk, Ivan V; Elez, Katarina; Raich, Lluís; Henry, Brandon M; Benoit, Justin L; Benoit, Stefanie W; Noé, Frank; Kehn-Hall, Kylene; Rothenberg, Marc E 2021. Alpha 1 Antitrypsin is an Inhibitor of the SARS-CoV-2-Priming Protease TMPRSS2. Pathogens & immunity, 6 1, 55-74

Benoit, Justin L; Stolz, Uwe; McMullan, Jason T; Wang, Henry E 2021. Duration of exposure to a prehospital advanced airway and neurological outcome for out-of-hospital cardiac arrest: A retrospective cohort study. Resuscitation, 160 , 59-65

Henry, Brandon M; Szergyuk, Ivan; de Oliveira, Maria Helena Santos; Abosamak, Mohammed Fawzi; Benoit, Stefanie W; Benoit, Justin L; Lippi, Giuseppe 2021. Alterations in the lipid profile associate with a dysregulated inflammatory, prothrombotic, anti-fibrinolytic state and development of severe acute kidney injury in coronavirus disease 2019 (COVID-19): A study from Cincinnati, USA. Diabetes & metabolic syndrome, 15 3, 863-868

Henry, Brandon Michael; Benoit, Justin L; Rose, James; de Oliveira, Maria Helena Santos; Lippi, Giuseppe; Benoit, Stefanie W 2021. Serum ACE activity and plasma ACE concentration in patients with SARS-CoV-2 infection. Scandinavian journal of clinical and laboratory investigation, , 1-4

Henry, Brandon Michael; Benoit, Stefanie W; Vikse, Jens; Berger, Brandon A; Pulvino, Christina; Hoehn, Jonathan; Rose, James; Santos de Oliveira, Maria Helena; Lippi, Giuseppe; Benoit, Justin L 2021. The anti-inflammatory cytokine response characterized by elevated interleukin-10 is a stronger predictor of severe disease and poor outcomes than the pro-inflammatory cytokine response in coronavirus disease 2019 (COVID-19). Clinical chemistry and laboratory medicine, 59 3, 599-607

Henry, Brandon Michael; Cheruiyot, Isaac; Benoit, Justin L; Lippi, Giuseppe; Prohászka, Zoltán; Favaloro, Emmanuel J; Benoit, Stefanie W 2021. Circulating Levels of Tissue Plasminogen Activator and Plasminogen Activator Inhibitor-1 Are Independent Predictors of Coronavirus Disease 2019 Severity: A Prospective, Observational Study. Seminars in thrombosis and hemostasis, ,

Henry, Brandon Michael; Cheruiyot, Isaac; Benoit, Stefanie W; Sanchis-Gomar, Fabian; Lippi, Giuseppe; Benoit, Justin 2021. Cytokeratin 18 cell death assays as biomarkers for quantification of apoptosis and necrosis in COVID-19: a prospective, observational study. Journal of clinical pathology, ,

Henry, Brandon Michael; de Oliveira, Maria Helena Santos; Cheruiyot, Isaac; Benoit, Justin L; Cooper, David S; Lippi, Giuseppe; Le Cras, Timothy D; Benoit, Stefanie W 2021. Circulating level of Angiopoietin-2 is associated with acute kidney injury in coronavirus disease 2019 (COVID-19). Angiogenesis, ,

Henry, Brandon Michael; Szergyuk, Ivan; de Oliveira, Maria Helena Santos; Lippi, Giuseppe; Benoit, Justin L; Vikse, Jens; Benoit, Stefanie W 2021. Complement levels at admission as a reflection of coronavirus disease 2019 (COVID-19) severity state. Journal of medical virology, ,

Henry, Brandon; Helena, Maria; Cheruiyot, Isaac; Benoit, Stefanie; Benoit, Justin; Lippi, Giuseppe 2021. Combined Cytokine Scores Assessed at Emergency Department Presentation Predicts COVID-19 Critical Illness. Acta bio-medica : Atenei Parmensis, 92 4, e2021248

Lippi, Giuseppe; Szergyuk, Ivan; de Oliveira, Maria Helena Santos; Benoit, Stefanie W; Benoit, Justin L; Favaloro, Emmanuel J; Henry, Brandon Michael 2021. The role of lipoprotein(a) in coronavirus disease 2019 (COVID-19) with relation to development of severe acute kidney injury. Journal of thrombosis and thrombolysis, ,

Okubo, Masashi; Komukai, Sho; Izawa, Junichi; Aufderheide, Tom P; Benoit, Justin L; Carlson, Jestin N; Daya, Mohamud R; Hansen, Matthew; Idris, Ahamed H; Le, Nancy; Lupton, Joshua R; Nichol, Graham; Wang, Henry E; Callaway, Clifton W 2021. Association of Advanced Airway Insertion Timing and Outcomes After Out-of-Hospital Cardiac Arrest. Annals of emergency medicine, ,

Spigner MF; Benoit JL; Menegazzi JJ; McMullan JT 2020. Prehospital Protocols for Post-Return of Spontaneous Circulation Are Highly Variable Prehospital Emergency Care, ,

Benoit J, Benoit S, Rose J, Lippi G, Henry BM 2020. Assessment of Immune Response Against SARS-CoV-2 at Emergency Department Evaluation in COVID-19 Patients Journal of Laboratory and Precision Medicine, 5 , 33

Benoit, Justin L; Benoit, Stefanie W; de Oliveira, Maria H S; Lippi, Giuseppe; Henry, Brandon M 2020. Anemia and COVID-19: A prospective perspective. Journal of medical virology, ,

Benoit, Justin L; Wang, Henry E 2020. Intubation for Out-of-Hospital Cardiac Arrest: The Elephant Is in the Room. Annals of emergency medicine, 75 5, 637-639

Benoit, Justin; Benoit, Stefanie W; Lippi, Giuseppe; Henry, Brandon Michael 2020. False negative RT-PCR or false positive serological testing in SARS-CoV-2 diagnostics? Navigating between Scylla and Charybdis to prevent misclassification bias in COVID-19 clinical investigations. Diagnosis (Berlin, Germany), ,

Henry, Brandon M; Benoit, Justin L; Berger, Brandon A; Pulvino, Christina; Lavie, Carl J; Lippi, Giuseppe; Benoit, Stefanie W 2020. Coronavirus disease 2019 is associated with low circulating plasma levels of angiotensin 1 and angiotensin 1,7. Journal of medical virology, ,

Henry, Brandon Michael; Benoit, Justin Lee; Benoit, Stefanie; Pulvino, Christina; Berger, Brandon A; Olivera, Maria Helena Santos de; Crutchfield, Christopher A; Lippi, Giuseppe 2020. Red Blood Cell Distribution Width (RDW) Predicts COVID-19 Severity: A Prospective, Observational Study from the Cincinnati SARS-CoV-2 Emergency Department Cohort. Diagnostics (Basel, Switzerland), 10 9,

Henry, Brandon Michael; Benoit, Stefanie W; de Oliveira, Maria Helena Santos; Hsieh, Wan Chin; Benoit, Justin; Ballout, Rami A; Plebani, Mario; Lippi, Giuseppe 2020. Laboratory abnormalities in children with mild and severe coronavirus disease 2019 (COVID-19): A pooled analysis and review. Clinical biochemistry, 81 , 1-8

Henry, Brandon Michael; Benoit, Stefanie W; de Oliveira, Maria Helena Santos; Lippi, Giuseppe; Favaloro, Emmanuel J; Benoit, Justin L 2020. ADAMTS13 activity to von Willebrand factor antigen ratio predicts acute kidney injury in patients with COVID-19: Evidence of SARS-CoV-2 induced secondary thrombotic microangiopathy. International journal of laboratory hematology, ,

Henry, Brandon Michael; Benoit, Stefanie W; Hoehn, Jonathan; Lippi, Giuseppe; Favaloro, Emmanuel J; Benoit, Justin L 2020. Circulating Plasminogen Concentration at Admission in Patients with Coronavirus Disease 2019 (COVID-19). Seminars in thrombosis and hemostasis, 46 7, 859-862

Henry, Brandon Michael; Benoit, Stefanie; Lippi, Giuseppe; Benoit, Justin 2020. Circulating plasma levels of angiotensin II and aldosterone in patients with coronavirus disease 2019 (COVID-19): A preliminary report. Progress in cardiovascular diseases, ,

Henry, Brandon Michael; de Oliveira, Maria Helena Santos; Benoit, Justin; Lippi, Giuseppe 2020. Gastrointestinal symptoms associated with severity of coronavirus disease 2019 (COVID-19): a pooled analysis. Internal and emergency medicine, ,

Henry, Brandon; Cheruiyot, Isaac; Vikse, Jens; Mutua, Victor; Kipkorir, Vincent; Benoit, Justin; Plebani, Mario; Bragazzi, Nicola; Lippi, Giuseppe 2020. Lymphopenia and neutrophilia at admission predicts severity and mortality in patients with COVID-19: a meta-analysis. Acta bio-medica : Atenei Parmensis, 91 3, e2020008

Lippi, Giuseppe; Henry, Brandon Michael; Hoehn, Jonathan; Benoit, Stefanie; Benoit, Justin 2020. Validation of the Corona-Score for rapid identification of SARS-CoV-2 infections in patients seeking emergency department care in the United States. Clinical chemistry and laboratory medicine, ,

Neth, Matthew R; Benoit, Justin L; Stolz, Uwe; McMullan, Jason 2020. Ventilation in Simulated Out-of-Hospital Cardiac Arrest Resuscitation Rarely Meets Guidelines. Prehospital emergency care : official journal of the National Association of EMS Physicians and the National Association of State EMS Directors, , 1-9

Neth, Matthew R; Idris, Ahamed; McMullan, Jason; Benoit, Justin L; Daya, Mohamud R 2020. A review of ventilation in adult out-of-hospital cardiac arrest. Journal of the American College of Emergency Physicians open, 1 3, 190-201

Panchal, Ashish R; Bartos, Jason A; Cabañas, José G; Donnino, Michael W; Drennan, Ian R; Hirsch, Karen G; Kudenchuk, Peter J; Kurz, Michael C; Lavonas, Eric J; Morley, Peter T; O'Neil, Brian J; Peberdy, Mary Ann; Rittenberger, Jon C; Rodriguez, Amber J; Sawyer, Kelly N; Berg, Katherine M 2020. Part 3: Adult Basic and Advanced Life Support: 2020 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation, 142 16_suppl_2, S366-S468

Soar, Jasmeet; Berg, Katherine M; Andersen, Lars W; Böttiger, Bernd W; Cacciola, Sofia; Callaway, Clifton W; Couper, Keith; Cronberg, Tobias; D'Arrigo, Sonia; Deakin, Charles D; Donnino, Michael W; Drennan, Ian R; Granfeldt, Asger; Hoedemaekers, Cornelia W E; Holmberg, Mathias J; Hsu, Cindy H; Kamps, Marlijn; Musiol, Szymon; Nation, Kevin J; Neumar, Robert W; Nicholson, Tonia; O'Neil, Brian J; Otto, Quentin; de Paiva, Edison Ferreira; Parr, Michael J A; Reynolds, Joshua C; Sandroni, Claudio; Scholefield, Barnaby R; Skrifvars, Markus B; Wang, Tzong-Luen; Wetsch, Wolfgang A; Yeung, Joyce; Morley, Peter T; Morrison, Laurie J; Welsford, Michelle; Hazinski, Mary Fran; Nolan, Jerry P 2020. Adult Advanced Life Support: 2020 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science with Treatment Recommendations. Resuscitation, 156 , A80-A119

Monette, Derek L; Brown, Calvin A; Benoit, Justin L; McMullan, Jason T; Carleton, Steven C; Steuerwald, Michael T; Eyre, Andrew; Pallin, Daniel J 2019. The Impact of Video Laryngoscopy on the Clinical Learning Environment of Emergency Medicine Residents: A Report of 14,313 Intubations. AEM education and training, 3 2, 156-162

Benoit, Justin L; Hart, Kimberly W; Soliman, Adam A; Barczak, Christopher M; Sibilia, Robert S; Lindsell, Christopher J; Fermann, Gregory J 2017. Developing a standardized measurement of alcohol intoxication. The American journal of emergency medicine, 35 5, 725-730

Benoit, Justin L; Vogele, Jennifer; Hart, Kimberly W; Lindsell, Christopher J; McMullan, Jason T 2017. Passive ultra-brief video training improves performance of compression-only cardiopulmonary resuscitation. Resuscitation, 115 , 116-119

Benoit, Justin L; Widmeier, Keith C; McMullan, Jason T 2017. Evaluating Research: Seven essential questions to evaluate clinical research. JEMS : a journal of emergency medical services, 42 2, 50-3

Strong DW, Benoit JL, Calhoun DJ 2017. University of Cincinnati Tactical EMS: A Resident Physician Experience Tactical Edge, Winter, 72-77

Benoit, Justin L; Gerecht, Ryan B; Steuerwald, Michael T; McMullan, Jason T 2015. Endotracheal intubation versus supraglottic airway placement in out-of-hospital cardiac arrest: A meta-analysis. Resuscitation, 93 , 20-6

Benoit, Justin L; Prince, David K; Wang, Henry E 2015. Mechanisms linking advanced airway management and cardiac arrest outcomes. Resuscitation, 93 , 124-7

Hicks, Caitlin W; Engineer, Rakesh S; Benoit, Justin L; Dasarathy, Srinivasan; Christenson, Robert H; Peacock, William F 2014. Procalcitonin as a biomarker for early sepsis in the emergency department. European journal of emergency medicine : official journal of the European Society for Emergency Medicine, 21 2, 112-7

McMullan, Jason; Benoit, Justin 2014. Airway choices matter. The effect of prehospital airway management on cardiac arrest outcomes. JEMS : a journal of emergency medical services, Suppl , 4-7

Benoit, Justin L; Hicks, Caitlin W; Engineer, Rakesh S; Hart, Kimberly W; Lindsell, Christopher J; Peacock, William F 2013. ST2 in emergency department patients with noncardiac dyspnea. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 20 11, 1207-10

Engineer, Rakesh S; Benoit, Justin L; Hicks, Caitlin W; Kolattukudy, Sunny J; Burkhoff, Daniel; Peacock, W Frank 2012. Hemodynamic changes as a diagnostic tool in acute heart failure--a pilot study. The American journal of emergency medicine, 30 1, 174-80

Benoit, Justin L; Khatri, Pooja; Adeoye, Opeolu M; Broderick, Joseph P; McMullan, Jason T; Scheitz, Jan F; Vagal, Achala S; Eckman, Mark H . Prehospital Triage of Acute Ischemic Stroke Patients to an Intravenous tPA-Ready versus Endovascular-Ready Hospital: A Decision Analysis. Prehospital emergency care : official journal of the National Association of EMS Physicians and the National Association of State EMS Directors, 22 6, 722-733

Benoit, Justin L; McMullan, Jason T; Wang, Henry E; Xie, Changchun; Xu, Peixin; Hart, Kimberly W; Stolz, Uwe; Lindsell, Christopher J . Timing of Advanced Airway Placement after Witnessed Out-of-Hospital Cardiac Arrest. Prehospital emergency care : official journal of the National Association of EMS Physicians and the National Association of State EMS Directors, 23 6, 838-846