Today is Monday, May. 25, 2020

Department of Internal Medicine

Nephrology and Hypertension

Photo of  Manoocher Soleimani, MD

Manoocher Soleimani, MD

Professor of Medicine; Associate Chair for Research, Department of Medicine

Clinical Interest


  • Medical Degree: Shiraz University School of Medicine
  • Fellowship: Yale University School of Medicine
  • Residency: Shiraz University School of Medicine
Board Certifications & Licenses
  • American Board of Internal Medicine 08/22/2000
  • American Board of Internal Medicine (Nephrology) 10/03/2018
Contact Information
  • Internal Medicine
  • Medical Sciences Building Room G362
  • 231 Albert Sabin Way
  • Cincinnati, Ohio 45267
  • Office 513-558-5471
  • Fax 513-558-4309
  • Email

Peer Reviewed Publications

Amlal H, Xu J, Barone S, Zahedi K, Soleimani M 2013. The chloride channel/transporter Slc26a9 regulates the systemic arterial pressure and renal chloride excretion J Molec Med, 91 5, 561-572

Li HC, Du Z, Barone S, Rubera I, McDonough AA, Tauc M, Zahedi K, Wang T, Soleimani M 2013. Proximal tubule specific knockout of the Na+/H+ exchanger NHE3: effects of bicarbonate absoprtion and ammonium excretion J Mol Med, ,

Soleimani M 2013. SLC26 Cl-HCO3- exchangers in the kidneys: roles in health and disease Kidney International, ,

Anagnostopoulou P, Riederer B, Duerr J, Michel S, Binia A, Agrawal R, Liu X, Kalitzki K, Xiao F, Chen M, Schatterny J, Hartmann D, Thum T, Kabesch M, Soleimani M, Seidler U, Mall M 2012. SLC26A9-mediated chloride secretion prevents mucus obstruction in airwar inflammation J Clin Invest, ,

Li HC, Kucher V, Li EY, Conforti L, Zahedi K, Soleimani M 2012. The role of aspartic acid residues 405 and 416 of the kidney isotope od sodium-bicarbonate cotransporter 1 in its targeting to the plasma membrane Am J Physiol Cell Physiol, 302 12, C1713-C1730

Soleimani S, Barone S, Xu J, Shull GE, Siddiqui F, Zahedi K, Amlal H 2012. Double knockout of pendrin and Na-Cl cotransporter (NCC) causes severe salt wasting, volume depletion, and renal failure Proc Natl Acad Sci U S A, 109 33, 13368-13373

Zahedi K, Barone S, Xu J, Steinbergs N, Schuster R, Lentsch AB, Amlal H, Wang J, Caero RA Jr, Soleimani M 2012. Hepatocyte-specific ablation of spermine/spermidine-N1-acetyltransferase gene reduces the severity of CC14-induced acute liver injury Am J Physiol: Gastrointestinal Liver Physiol, 303 5, G546-G560

Xu J, Barone S, Li H, Holiday S, Zahedi K, Soleimani M 2011. Slc26a11, a chloride transporter, localizes with the vacuolar H(+)-ATPase of A-intercalated cells of the kidney Kindey Int, 80 9, 926-937

Amlal H, Petrovic S, Xu J, Wang Z, Sun X, Barone S, Soleimani M 2010. Deletion of the anion exchanger Slc26a4 (pendrin) decreases apical Cl(-)/HCO3(-) exchanger activity and impairs bicarbonate secretion in kidney collecting duct Am J Physiol Cell Physiol, 299 1, C33-C41

Barone S, Fussell SL, SIngh AK, Lucas F, Xu J, Kim C, Wu X, Yu Y, Amlal H, Seidler U, Zuo J, Soleimani M 2009. Slc2a5 (Glut5) is essential for the absorption of fructose in the intestine and generation of fructose-induced hypertension J Biol Chem, 287 , 2056-5066

Li HC, Collier JH, Shawki A, Rudra JS, Li EY, Mackenzie B, Soleimani M 2009. Sequence- or position-specific mutations in the carboxyl terminal FL motif of the kidney sodium bicarbonate cotransporter (NBCI) disrupt its basolateral targeting and alpha-helical structure J Membr Biol, 228 , 111-124

Xu J, Song P, Nakamura S, Miller M, Barone S, Alper SL, Riederer B, Bonhagen J, Arend LJ, Amlal H, Seidler U, Soleimani M 2009. Deletion of the chloride transporter Slc26a7 causes distal renal tubular acidosis and impairs gastric acid secretion J Biol Chem, 282 , 29470-29479

Xu J, Song P, Miller ML, Borgese F, Barone S, Riederer B, Wang Z, Alper SL, Forte JG, Shull GE, Ehrenfield J, Seidler U, Soleimani M 2008. Deletion of the chloride transporter Slc26a9 causes loss of tubulovesicles in parietal cells and impairs acid secretion in the stomach Proc Natl Acad Sci USA, 105 , 17955-17960

Rahmati N, Kunzelmann K, Kongsuphol P, Xu J, barone S, De Zeeuw C, Soleimani M . Slc26a11 is a Chloride Channel in the Brain: Expression in Purkinje Cells and Stimulatin of V H+-ATPase Pflugers Archive, ,