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Photo of  Wei-Wen Hsu, PhD

Wei-Wen Hsu, PhD

Associate Professor

Environmental & Public Health Sciences | College of Medicine

  • PhD: Michigan State University, East Lansing, MI (Statistics)
  • MBA: National Taipei University, Taipei, Taiwan (Statistics)
  • BB: Tamkang University, Taipei, Taiwan (Statistics)
Contact Information
Research Interests

- Methodologies
Two-component Mixture Models, Classification Methods for High-Dimensional Data, Longitudinal and Correlated Data Analysis, Hypothesis Testing, Latent Class/Transition Model

- Subject Matter Applications
Cancer Research (Early Detection and Biomarker Discovery), Geriatric Research (Alzheimer's Disease), Environmental Exposure Research, Dental Caries Research, Mental Health Research

Peer Reviewed Publications

Sidana, Abhinav; Tayebi, Shima; Blank, Fernando; Lama, Daniel J; Meyer, Meredith; Saeed, Yusef; Tobler, Juliana; Hsu, Wei-Wen; Verma, Sadhna 2024. Magnetic resonance imaging-ultrasound fusion guided focal cryoablation for men with intermediate-risk prostate cancer. Urologic oncology, ,

Blank, Fernando; Meyer, Meredith; Wang, Hannah; Abbas, Hasan; Tayebi, Shima; Hsu, Wei-Wen; Sidana, Abhinav 2023. Salvage Radical Prostatectomy after Primary Focal Ablative Therapy: A Systematic Review and Meta-Analysis. Cancers, 15 10,

Chun, Colin K Y; Roth, Mary; Welti, Ruth; Richards, Mark P; Hsu, Wei-Wen; O 2023. Exploring the potential effect of phospholipase A2 antibody to extend beef shelf-life in a beef liposome model system. Meat science, 198 , 109091

Holovach, Phillip G; Hsu, Wei-Wen; Fleischer, Alan B 2023. Number Bias in Clinicians' Documentation of Actinic Keratosis Removal. Journal of clinical medicine, 13 1,

Todem, David; Hsu, Wei-Wen; Kim, KyungMann 2023. Nonparametric scanning tests of homogeneity for hierarchical models with continuous covariates. Biometrics, 79 3, 2063-2075

Hsu, Wei-Wen; Mawella, Nadeesha R; Todem, David 2022. On testing for homogeneity with zero-inflated models through the lens of model misspecification. International statistical review = Revue internationale de statistique, 90 1, 62-77

Li, Yiming; Hsu, Wei-Wen 2022. A classification for complex imbalanced data in disease screening and early diagnosis. Statistics in medicine, 41 19, 3679-3695

Horn, Andrew G; Kunkel, Olivia N; Baumfalk, Dryden R; Simon, Mikaela E; Schulze, Kiana M; Hsu, Wei-Wen; Muller-Delp, Judy; Poole, David C; Behnke, Bradley J 2021. Prolonged mechanical ventilation increases diaphragm arteriole circumferential stretch without changes in stress/stretch: Implications for the pathogenesis of ventilator-induced diaphragm dysfunction. Microcirculation (New York, N.Y. : 1994), 28, e12727

Huang, Yan-Jang S; Bilyeu, Ashley N; Hsu, Wei-Wen; Hettenbach, Susan M; Willix, Joshua L; Stewart, Savannah C; Higgs, Stephen; Vanlandingham, Dana L 2021. Treatment with dry hydrogen peroxide accelerates the decay of severe acute syndrome coronavirus-2 on non-porous hard surfaces. American journal of infection control, 49 10, 1252-1255

Schulze, Kiana M; Weber, Ramona E; Colburn, Trenton D; Horn, Andrew G; Ade, Carl J; Hsu, Wei-Wen; Poole, David C; Musch, Timothy I 2021. The effects of pulmonary hypertension on skeletal muscle oxygen pressures in contracting rat spinotrapezius muscle. Experimental physiology, 106 10, 2070-2082

Wang, Sheng-Chao; Liao, Li-Min; Ansar, Muhamad; Lin, Shih-Yun; Hsu, Wei-Wen; Su, Chih-Ming; Chung, Yu-Mei; Liu, Cai-Cing; Hung, Chin-Sheng; Lin, Ruo-Kai 2021. Automatic Detection of the Circulating Cell-Free Methylated DNA Pattern of GCM2, ITPRIPL1 and CCDC181 for Detection of Early Breast Cancer and Surgical Treatment Response. Cancers, 13 6,

Hsu, Wei-Wen; Todem, David; Mawella, Nadeesha R; Kim, KyungMann; Rosenkranz, Richard R 2020. A robust score test of homogeneity for zero-inflated count data. Statistical Methods in Medical Research, 29 12, 3653-3665

Chao, M.D., Donaldson,E.A., Wu, W.J., Hsu, W.-W., Shulte, M.D., and Lonergan, S.M. 2020. Characterizing membrane phospholipid hydrolysis of pork loins throughout three aging periods Meat Science, 163 , 108065

Fisher, Sycarah; Hsu, Wei-Wen; Adams, Zachary; Arsenault, Chelsea; Milich, Richard 2020. The effect of impulsivity and drinking motives on alcohol outcomes in college students: a 3-year longitudinal analysis. Journal of American College Health, , 1-10

Kusuma, Mutiara Tirta Prabandari Lintang; Kidd, Tandalayo; Muturi, Nancy; Procter, Sandra B; Yarrow, Linda; Hsu, Wei-Wen 2020. HIV knowledge and stigma among dietetic students in Indonesia: implications for the nutrition education system. BMC Infectious Diseases, 20 1, 663

Kusuma, Mutiara Tirta Prabandari Lintang; Kidd, Tandalayo; Muturi, Nancy; Procter, Sandra Butin; Yarrow, Linda; Hsu, Wei-Wen 2020. The Symbolic Meaning of HIV: Understanding Lecturers' Ambivalence over Teaching HIV to Dietetic Students. Journal of the International Association of Providers of AIDS Care, 19 ,

Young, Christian L; Lyons, Amy C; Hsu, Wei-Wen; Vanlandingham, Dana L; Park, So Lee; Bilyeu, Ashley N; Ayers, Victoria B; Hettenbach, Susan M; Zelenka, Ashley M; Cool, Konner R; Peterson, Gregory J; Higgs, Stephen; Huang, Yan-Jang S 2020. Protection of swine by potent neutralizing anti-Japanese encephalitis virus monoclonal antibodies derived from vaccination. Antiviral Research, 174 , 104675

Mailey, Emily L; Irwin, Brandon C; Joyce, Jillian M; Hsu, Wei-Wen 2019. InDependent but not Alone: A Web-Based Intervention to Promote Physical and Mental Health among Military Spouses. Applied Psychology: Health and Well-Being, 11 3, 562-583

Lyons, Amy C; Huang, Yan-Jang S; Park, So Lee; Ayers, Victoria B; Hettenbach, Susan M; Higgs, Stephen; McVey, D Scott; Noronha, Leela; Hsu, Wei-Wen; Vanlandingham, Dana L 2018. Shedding of Japanese Encephalitis Virus in Oral Fluid of Infected Swine. Vector Borne and Zoonotic Diseases (Larchmont, N.Y.), 18 9, 469-474

Mailey, Emily L., Dlugonski, Deirdre, Hsu, Wei-Wen; and Segar, Michelle 2018. Goals Matter: Exercising for well-being but not health or appearance predicts future exercise among parents Journal of Physical Activity & Health, 15 11, 857-865

Todem, David; Hsu, Wei-Wen; Fine, Jason P 2018. A quasi-score statistic for homogeneity testing against covariate-varying heterogeneity. Scandinavian Journal of Statistics, 45 3, 465-481

Huang, Yan-Jang S; Lyons, Amy C; Hsu, Wei-Wen; Park, So Lee; Higgs, Stephen; Vanlandingham, Dana L 2017. Differential outcomes of Zika virus infection in Aedes aegypti orally challenged with infectious blood meals and infectious protein meals. PloS One, 12 8, e0182386

Kolt, Gregory S; George, Emma S; Rebar, Amanda L; Duncan, Mitch J; Vandelanotte, Corneel; Caperchione, Cristina M; Maeder, Anthony J; Tague, Rhys; Savage, Trevor N; Van Itallie, Anetta; Mawella, Nadeesha R; Hsu, Wei-Wen; Mummery, W Kerry; Rosenkranz, Richard R 2017. Associations between quality of life and duration and frequency of physical activity and sedentary behaviour: Baseline findings from the WALK 2.0 randomised controlled trial. PloS One, 12 6, e0180072

Mailey, Emily L; Hsu, Wei-Wen 2017. Is a general or specific exercise recommendation more effective for promoting physical activity among postpartum mothers? Journal of Health Psychology, 24 7, 964-978

Hsu, Wei-Wen; Todem, David; Kim, KyungMann 2016. A sup-score test for the cure fraction in mixture models for long-term survivors. Biometrics, 72 4, 1348-1357

Han, Lisa; Hsu, Wei-Wen; Todem, David; Osuch, Janet; Hungerink, Angela; Karmaus, Wilfried 2016. In utero exposure to polychlorinated biphenyls is associated with decreased fecundability in daughters of Michigan female fisheaters: a cohort study. Environmental health, 15 1, 92

Htoo, Zaw Wai; Hsu, Wei-Wen; Rosenkranz, Richard 2016. Systematic review and meta-analysis: Is lifestyle modification effective for glycemic control among adults with type II diabetes in Southeast Asia? Diabetes Research and Clinical Practice, 122 , 148-153

Huang, Yan-Jang S; Hettenbach, Susan M; Park, So Lee; Higgs, Stephen; Barrett, Alan D T; Hsu, Wei-Wen; Harbin, Julie N; Cohnstaedt, Lee W; Vanlandingham, Dana L 2016. Differential Infectivities among Different Japanese Encephalitis Virus Genotypes in Culex quinquefasciatus Mosquitoes. PLoS Neglected Tropical Diseases, 10 10, e0005038

Obaro, Stephen K.; Daniel, Yvonne; Lawson, Juliana O.; Hsu Wei-Wen; Dada, John; Essen, Uduak; Ibrahim, Khalid; Akindele, Adebayo; Brook, Kevin; Olanipekun, Grace; Ajose, Theresa; Stewart, Claire E.; and Inusa, Baba P.D. 2016. Sickle-Cell Disease in Nigerian Children: Parental Knowledge and Laboratory Results Public Health Genomic, 19 , 102-107

Park, So Lee; Huang, Yan-Jang S; Hsu, Wei-Wen; Hettenbach, Susan M; Higgs, Stephen; Vanlandingham, Dana L 2016. Virus-specific thermostability and heat inactivation profiles of alphaviruses. Journal of Virological Methods, 234 , 152-5

Todem, David; Kim, KyungMann; Hsu, Wei-Wen 2016. Marginal mean models for zero-inflated count data. Biometrics, 72 3, 986-94

Zapolski, Tamika C B; Fisher, Sycarah; Hsu, Wei-Wen; Barnes, Jessica 2016. What can parents do? Examining the role of parental support on the negative relationship between racial discrimination, depression, and drug use among African American youth. Clinical Psychological Science, 4 4, 718-731

Hsu, Wei-Wen; Todem, David; Kim, KyungMann 2015. Adjusted Supremum Score-Type Statistics for Evaluating Non-Standard Hypotheses Scandinavian Journal of Statistics, 42 , 746-759

Huang, Yan-Jang S; Hsu, Wei-Wen; Higgs, Stephen; Vanlandingham, Dana L 2015. Temperature Tolerance and Inactivation of Chikungunya Virus. Vector Borne and Zoonotic Diseases (Larchmont, N.Y.), 15 11, 674-7

Wendel, Sebastian O; Menon, Sailesh; Alshetaiwi, Hamad; Shrestha, Tej B; Chlebanowski, Lauren; Hsu, Wei-Wen; Bossmann, Stefan H; Narayanan, Sanjeev; Troyer, Deryl L 2015. Cell Based Drug Delivery: Micrococcus luteus Loaded Neutrophils as Chlorhexidine Delivery Vehicles in a Mouse Model of Liver Abscesses in Cattle. PloS One, 10 5, e0128144

Hsu, Wei-Wen; Osuch, Janet Rose; Todem, David; Taffe, Bonita; O 2014. DDE and PCB serum concentration in maternal blood and their adult female offspring. Environmental Research, 132 , 384-90

Hsu, Wei-Wen; Todem, David; Kim, KyungMann and Sohn, Woosung 2014. A Wald test for zero inflation and deflation for correlated count data from dental caries research Statistical Modelling, 14 6, 471-488

Cao, Quanqun; Hsu, Wei-Wen and Todem, David 2014. A score-type test for heterogeneity in zero-inflated models in a stratified population Statistics in Medicine, 33 12, 2103-2114

Fisher, Sycarah; Reynolds, Jennifer; Hsu, Wei-Wen; Barnes, Jessica; and Tyler, Kenneth 2014. Examining Multiracial Youth in Context: Ethnic Identity Development and Mental Health Outcomes Journal of Youth and Adolescence, 43 10, 1688-1699

Osuch, Janet; Hsu, Wei-Wen; Todem, David; Landgraf, Jeffrey; Mikucki, Dorota; Haan, Pam S; Karmaus, Wilfried 2012. Female reproductive status and circulating blood leukocyte expression of selected metabolic or signaling genes involved in sex steroid metabolism International Journal of Molecular Epidemiology and Genetics, 3 2, 134-143

Todem, David; Hsu, Wei-Wen; Kim, KyungMann 2012. On the efficiency of score tests for homogeneity in two-component parametric models for discrete data Biometrics, 68 3, 975-982