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Photo of Christina Gross, PhD

Christina Gross, PhD

Associate Professor-Affiliate

Pediatrics | College of Medicine

Contact Information

Peer Reviewed Publications

Tiwari, Durgesh; Peariso, Katrina; Gross, Christina 2018. MicroRNA-induced silencing in epilepsy: Opportunities and challenges for clinical application. Developmental dynamics : an official publication of the American Association of Anatomists, 247 1, 94-110

Bienkowski, Rick S; Banerjee, Ayan; Rounds, J Christopher; Rha, Jennifer; Omotade, Omotola F; Gross, Christina; Morris, Kevin J; Leung, Sara W; Pak, ChangHui; Jones, Stephanie K; Santoro, Michael R; Warren, Stephen T; Zheng, James Q; Bassell, Gary J; Corbett, Anita H; Moberg, Kenneth H 2017. The Conserved, Disease-Associated RNA Binding Protein dNab2 Interacts with the Fragile X Protein Ortholog in Drosophila Neurons. Cell reports, 20 6, 1372-1384

Gross, Christina 2017. Defective phosphoinositide metabolism in autism. Journal of neuroscience research, 95 5, 1161-1173

Ivanova, Tamara N; Gross, Christina; Mappus, Rudolph C; Kwon, Yong Jun; Bassell, Gary J; Liu, Robert C 2017. Familiarity with a vocal category biases the compartmental expression ofArc/Arg3.1in core auditory cortex. Learning & memory (Cold Spring Harbor, N.Y.), 24 12, 612-621

Gross, Christina; Yao, Xiaodi; Engel, Tobias; Tiwari, Durgesh; Xing, Lei; Rowley, Shane; Danielson, Scott W; Thomas, Kristen T; Jimenez-Mateos, Eva M; Schroeder, Lindsay M; Pun, Raymund Y K; Danzer, Steve C; Henshall, David C; Bassell, Gary J 2016. MicroRNA-Mediated Downregulation of the Potassium Channel Kv4.2 Contributes to Seizure Onset. Cell reports, 17 1, 37-45

Poopal, Ashwini C; Schroeder, Lindsay M; Horn, Paul S; Bassell, Gary J; Gross, Christina 2016. Increased expression of the PI3K catalytic subunit p110? underlies elevated S6 phosphorylation and protein synthesis in an individual with autism from a multiplex family. Molecular autism, 7 , 3

Wang, Eric T; Taliaferro, J Matthew; Lee, Ji-Ann; Sudhakaran, Indulekha P; Rossoll, Wilfried; Gross, Christina; Moss, Kathryn R; Bassell, Gary J 2016. Dysregulation of mRNA Localization and Translation in Genetic Disease. The Journal of neuroscience : the official journal of the Society for Neuroscience, 36 45, 11418-11426

Gross, Christina; Chang, Chia-Wei; Kelly, Seth M; Bhattacharya, Aditi; McBride, Sean M J; Danielson, Scott W; Jiang, Michael Q; Chan, Chi Bun; Ye, Keqiang; Gibson, Jay R; Klann, Eric; Jongens, Thomas A; Moberg, Kenneth H; Huber, Kimberly M; Bassell, Gary J 2015. Increased expression of the PI3K enhancer PIKE mediates deficits in synaptic plasticity and behavior in fragile X syndrome. Cell reports, 11 5, 727-36

Gross, Christina; Hoffmann, Anne; Bassell, Gary J; Berry-Kravis, Elizabeth M 2015. Therapeutic Strategies in Fragile X Syndrome: From Bench to Bedside and Back. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 12 3, 584-608

Gross, Christina; Raj, Nisha; Molinaro, Gemma; Allen, Amanda G; Whyte, Alonzo J; Gibson, Jay R; Huber, Kimberly M; Gourley, Shannon L; Bassell, Gary J 2015. Selective role of the catalytic PI3K subunit p110? in impaired higher order cognition in fragile X syndrome. Cell reports, 11 5, 681-8

Gross, Christina; Bassell, Gary J 2014. Neuron-specific regulation of class I PI3K catalytic subunits and their dysfunction in brain disorders. Frontiers in molecular neuroscience, 7 , 12

Sasaki, Yukio; Gross, Christina; Xing, Lei; Goshima, Yoshio; Bassell, Gary J 2014. Identification of axon-enriched microRNAs localized to growth cones of cortical neurons. Developmental neurobiology, 74 3, 397-406

Jakkamsetti, Vikram; Tsai, Nien-Pei; Gross, Christina; Molinaro, Gemma; Collins, Katie A; Nicoletti, Ferdinando; Wang, Kuan H; Osten, Pavel; Bassell, Gary J; Gibson, Jay R; Huber, Kimberly M 2013. Experience-induced Arc/Arg3.1 primes CA1 pyramidal neurons for metabotropic glutamate receptor-dependent long-term synaptic depression. Neuron, 80 1, 72-9

Larimore, Jennifer; Ryder, Pearl V; Kim, Kun-Yong; Ambrose, L Alex; Chapleau, Christopher; Calfa, Gaston; Gross, Christina; Bassell, Gary J; Pozzo-Miller, Lucas; Smith, Yoland; Talbot, Konrad; Park, In-Hyun; Faundez, Victor 2013. MeCP2 regulates the synaptic expression of a Dysbindin-BLOC-1 network component in mouse brain and human induced pluripotent stem cell-derived neurons. PloS one, 8 6, e65069

Gross, Christina; Bassell, Gary J 2012. Excess protein synthesis in FXS patient lymphoblastoid cells can be rescued with a p110?-selective inhibitor. Molecular medicine (Cambridge, Mass.), 18 , 336-45

Gross, Christina; Berry-Kravis, Elizabeth M; Bassell, Gary J 2012. Therapeutic strategies in fragile X syndrome: dysregulated mGluR signaling and beyond. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 37 1, 178-95

Nalavadi, Vijayalaxmi C; Muddashetty, Ravi S; Gross, Christina; Bassell, Gary J 2012. Dephosphorylation-induced ubiquitination and degradation of FMRP in dendrites: a role in immediate early mGluR-stimulated translation. The Journal of neuroscience : the official journal of the Society for Neuroscience, 32 8, 2582-7

Gross, Christina; Yao, Xiaodi; Pong, Dan L; Jeromin, Andreas; Bassell, Gary J 2011. Fragile X mental retardation protein regulates protein expression and mRNA translation of the potassium channel Kv4.2. The Journal of neuroscience : the official journal of the Society for Neuroscience, 31 15, 5693-8

Ivanova, T N; Matthews, A; Gross, C; Mappus, R C; Gollnick, C; Swanson, A; Bassell, G J; Liu, R C 2011. Arc/Arg3.1 mRNA expression reveals a subcellular trace of prior sound exposure in adult primary auditory cortex. Neuroscience, 181 , 117-26

Muddashetty, Ravi S; Nalavadi, Vijayalaxmi C; Gross, Christina; Yao, Xiaodi; Xing, Lei; Laur, Oskar; Warren, Stephen T; Bassell, Gary J 2011. Reversible inhibition of PSD-95 mRNA translation by miR-125a, FMRP phosphorylation, and mGluR signaling. Molecular cell, 42 5, 673-88

Pak, Changhui; Garshasbi, Masoud; Kahrizi, Kimia; Gross, Christina; Apponi, Luciano H; Noto, John J; Kelly, Seth M; Leung, Sara W; Tzschach, Andreas; Behjati, Farkhondeh; Abedini, Seyedeh Sedigheh; Mohseni, Marzieh; Jensen, Lars R; Hu, Hao; Huang, Brenda; Stahley, Sara N; Liu, Guanglu; Williams, Kathryn R; Burdick, Sharon; Feng, Yue; Sanyal, Subhabrata; Bassell, Gary J; Ropers, Hans-Hilger; Najmabadi, Hossein; Corbett, Anita H; Moberg, Kenneth H; Kuss, Andreas W 2011. Mutation of the conserved polyadenosine RNA binding protein, ZC3H14/dNab2, impairs neural function in Drosophila and humans. Proceedings of the National Academy of Sciences of the United States of America, 108 30, 12390-5

Swanger, Sharon A; Bassell, Gary J; Gross, Christina 2011. High-resolution fluorescence in situ hybridization to detect mRNAs in neuronal compartments in vitro and in vivo. Methods in molecular biology (Clifton, N.J.), 714 , 103-23

Swanger, Sharon A; Yao, Xiaodi; Gross, Christina; Bassell, Gary J 2011. Automated 4D analysis of dendritic spine morphology: applications to stimulus-induced spine remodeling and pharmacological rescue in a disease model. Molecular brain, 4 , 38

Gross, Christina; Nakamoto, Mika; Yao, Xiaodi; Chan, Chi-Bun; Yim, So Y; Ye, Keqiang; Warren, Stephen T; Bassell, Gary J 2010. Excess phosphoinositide 3-kinase subunit synthesis and activity as a novel therapeutic target in fragile X syndrome. The Journal of neuroscience : the official journal of the Society for Neuroscience, 30 32, 10624-38

Bassell, Gary J; Gross, Christina 2008. Reducing glutamate signaling pays off in fragile X. Nature medicine, 14 3, 249-50

Muddashetty, Ravi S; Keli?, Sofija; Gross, Christina; Xu, Mei; Bassell, Gary J 2007. Dysregulated metabotropic glutamate receptor-dependent translation of AMPA receptor and postsynaptic density-95 mRNAs at synapses in a mouse model of fragile X syndrome. The Journal of neuroscience : the official journal of the Society for Neuroscience, 27 20, 5338-48

Plath, Niels; Ohana, Ora; Dammermann, Björn; Errington, Mick L; Schmitz, Dietmar; Gross, Christina; Mao, Xiaosong; Engelsberg, Arne; Mahlke, Claudia; Welzl, Hans; Kobalz, Ursula; Stawrakakis, Anastasia; Fernandez, Esperanza; Waltereit, Robert; Bick-Sander, Anika; Therstappen, Eric; Cooke, Sam F; Blanquet, Veronique; Wurst, Wolfgang; Salmen, Benedikt; Bösl, Michael R; Lipp, Hans-Peter; Grant, Seth G N; Bliss, Tim V P; Wolfer, David P; Kuhl, Dietmar 2006. Arc/Arg3.1 is essential for the consolidation of synaptic plasticity and memories. Neuron, 52 3, 437-44

Gross, C; Heumann, R; Erdmann, K S 2001. The protein kinase C-related kinase PRK2 interacts with the protein tyrosine phosphatase PTP-BL via a novel PDZ domain binding motif. FEBS letters, 496 2-3, 101-4