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Robert M. Cohen, MD

Professor

Internal Medicine | College of Medicine

Education/Credentials
  • Fellowship: University of Chicago (Section of Endocrinology, Department of Medicine )
  • Internship & Residency: Rush-Presbyterian-St. Luke's Medical Center (Department of Medicine )
  • Medical Degree: University of Rochester School of Medicine & Dentistry
  • Bachelor's Degree: Amherst College
Board Certifications & Licenses

American Board of Internal Medicine (Endocrinology and Metabolism) (Certification Date: 1983-11-08)
American Board of Internal Medicine (Certification Date: 1981-09-16)

Specialties

Endocrinology-Diabetes and Metabolism
Internal Medicine

Contact Information
Research Interests

Board certified in Internal Medicine and Endocrinology with Particular Interest in Diabetes, Clinical Investigation, Endocrinology, Non-glycemic Mechanisms Affecting Hemoglobin A1c and Their Possible Role in the Complications of Diabetes, Diabetes Clinical Trials, Including the ACCORD (action to control cardiovascular risk in diabetes) Trial.

Clinical Interests

Diabetes

Endocrinology

Adrenal Insufficiency

Diabetes Mellitus

Hyperglycemia

Hyperinsulinism

Insulin Resistance

Insulinoma

Low Blood Sugar (Hypoglycemia)

Pre-Diabetes

Peer Reviewed Publications

Cherrington, Andrea L; Tripputi, Mark T; Younes, Naji; Herman, William H; Katona, Aimee; Groessl, Erik J; Craig, Jacqueline; Gonzalez, Jeffrey S; Garg, Rajesh; Casula, Sabina; Kuo, Shihchen; Florez, Hermes J 2024. Impact of Glucose-Lowering Medications on Health-Related Quality of Life in Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE). Diabetes care, ,

Friedman, Jared G; Smith, Eric P; Awasty, Sanjana S; Behan, Morgan; Genco, Matthew T; Hempel, Hannah; Jafri, Sabih; Jandarov, Roman; Nagaraj, Tara; Franco, Robert S; Cohen, Robert M 2024. Primary care diabetes assessment when HbA1c and other measures of glycemia disagree. Primary care diabetes, ,

Garvey, W Timothy; Cohen, Robert M; Butera, Nicole M; Kazemi, Erin J; Younes, Naji; Rosin, Samuel P; Suratt, Colleen E; Ahmann, Andrew; Hollander, Priscilla A; Krakoff, Jonathan; Martin, Catherine L; Seaquist, Elizabeth; Steffes, Michael W; Lachin, John M 2024. Association of Baseline Factors With Glycemic Outcomes in GRADE: A Comparative Effectiveness Randomized Clinical Trial. Diabetes care, ,

Hampe, Christiane S; Shojaie, Ali; Brooks-Worrell, Barbara; Dibay, Sepideh; Utzschneider, Kristina; Kahn, Steven E; Larkin, Mary E; Johnson, Mary L; Younes, Naji; Rasouli, Neda; Desouza, Cyrus; Cohen, Robert M; Park, Jean Y; Florez, Hermes J; Valencia, Willy Marcos; Stempel, Robert; Palmer, Jerry P; Balasubramanyam, Ashok 2024. GAD65Abs Are Not Associated With Beta-Cell Dysfunction in Patients With T2D in the GRADE Study. Journal of the Endocrine Society, 8 3, bvad179

Rasouli, Neda; Younes, Naji; Ghosh, Alokananda; Albu, Jeanine; Cohen, Robert M; DeFronzo, Ralph A; Diaz, Elsa; Sayyed Kassem, Laure; Luchsinger, José A; McGill, Janet B; Sivitz, William I; Tamborlane, William V; Utzschneider, Kristina M; Kahn, Steven E 2024. Longitudinal Effects of Glucose-Lowering Medications on β-Cell Responses and Insulin Sensitivity in Type 2 Diabetes: The GRADE Randomized Clinical Trial. Diabetes care, ,

, ; Nathan, David M; Lachin, John M; Balasubramanyam, Ashok; Burch, Henry B; Buse, John B; Butera, Nicole M; Cohen, Robert M; Crandall, Jill P; Kahn, Steven E; Krause-Steinrauf, Heidi; Larkin, Mary E; Rasouli, Neda; Tiktin, Margaret; Wexler, Deborah J; Younes, Naji 2022. Glycemia Reduction in Type 2 Diabetes - Glycemic Outcomes. The New England journal of medicine, 387 12, 1063-1074

Brooks-Worrell, Barbara; Hampe, Christiane S; Hattery, Erica G; Palomino, Brenda; Zangeneh, Sahar Z; Utzschneider, Kristina; Kahn, Steven E; Larkin, Mary E; Johnson, Mary L; Mather, Kieren J; Younes, Naji; Rasouli, Neda; Desouza, Cyrus; Cohen, Robert M; Park, Jean Y; Florez, Hermes J; Valencia, Willy Marcos ; Shojaie, Ali; Palmer, Jerry P; Balasubramanyam, Ashok 2022. Islet Autoimmunity is Highly Prevalent and Associated With Diminished ?-Cell Function in Patients With Type 2 Diabetes in the Grade Study. Diabetes, ,

Barzilay, Joshua I; Ghosh, Alokananda; Busui, Rodica Pop; Ahmann, Andrew; Balasubramanyam, Ashok; Banerji, Mary Ann; Cohen, Robert M; Green, Jennifer; Ismail-Beigi, Faramarz; Martin, Catherine L; Seaquist, Elizabeth; Luchsinger, José A 2021. The cross-sectional association of cognition with diabetic peripheral and autonomic neuropathy-The GRADE study. Journal of diabetes and its complications, 35 12, 108047

Utzschneider, Kristina M; Younes, Naji; Rasouli, Neda; Barzilay, Joshua I; Banerji, Mary Ann; Cohen, Robert M; Gonzalez, Erica V; Ismail-Beigi, Faramarz; Mather, Kieren J; Raskin, Philip; Wexler, Deborah J; Lachin, John M; Kahn, Steven E 2021. Shape of the OGTT glucose response curve: relationship with ?-cell function and differences by sex, race, and BMI in adults with early type 2 diabetes treated with metformin. BMJ open diabetes research & care, 9 1,

Utzschneider, Kristina M; Younes, Naji; Rasouli, Neda; Barzilay, Joshua; Banerji, Mary Ann; Cohen, Robert M; Gonzalez, Erica V; Mather, Kieren J; Ismail-Beigi, Faramarz; Raskin, Philip; Wexler, Deborah J; Lachin, John M; Kahn, Steven E 2021. Association of glycemia with insulin sensitivity and ?-cell function in adults with early type 2 diabetes on metformin alone. Journal of diabetes and its complications, 35 5, 107912

Bari, Khurram; Shah, Shimul A; Kaiser, Tiffany E; Cohen, Robert M; Anwar, Nadeem; Kleesattel, David; Sherman, Kenneth E 2020. Safety and Efficacy of Budesonide for Liver Transplant Immune Suppression: Results of a Pilot Phase 2a Trial. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, ,

Mather, Kieren J; Bebu, Ionut; Baker, Chelsea; Cohen, Robert M; Crandall, Jill P; DeSouza, Cyrus; Green, Jennifer B; Kirkman, M Sue; Krause-Steinrauf, Heidi; Larkin, Mary; Pettus, Jeremy; Seaquist, Elizabeth R; Soliman, Elsayed Z; Schroeder, Emily B; Wexler, Deborah J; Pop-Busui, Rodica 2020. Prevalence of microvascular and macrovascular disease in the Glycemia Reduction Approaches in Diabetes - A Comparative Effectiveness (GRADE) Study cohort. Diabetes research and clinical practice, 165 , 108235

Rasouli, Neda; Younes, Naji; Utzschneider, Kristina M; Inzucchi, Silvio E; Balasubramanyam, Ashok; Cherrington, Andrea L; Ismail-Beigi, Faramarz; Cohen, Robert M; Olson, Darin E; DeFronzo, Ralph A; Herman, William H; Lachin, John M; Kahn, Steven E 2020. Association of Baseline Characteristics With Insulin Sensitivity and ?-Cell Function in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness (GRADE) Study Cohort. Diabetes care, ,

Sivitz, William I; Phillips, Lawrence S; Wexler, Deborah J; Fortmann, Stephen P; Camp, Anne W; Tiktin, Margaret; Perez, Magalys; Craig, Jacqueline; Hollander, Priscilla A; Cherrington, Andrea; Aroda, Vanita R; Tan, Meng Hee; Krakoff, Jonathan; Rasouli, Neda; Butera, Nicole M; Younes, Naji 2020. Optimization of Metformin in the GRADE Cohort: Effect on Glycemia and Body Weight. Diabetes care, 43 5, 940-947

Angellotti, Edith; D'Alessio, David; Dawson-Hughes, Bess; Chu, Yan; Nelson, Jason; Hu, Peter; Cohen, Robert M; Pittas, Anastassios G 2019. Effect of vitamin D supplementation on cardiovascular risk in type 2 diabetes. Clinical nutrition (Edinburgh, Scotland), 38 5, 2449-2453

Cohen, Robert M; Franco, Robert S; Smith, Eric P; Higgins, John M 2019. When HbA1c and Blood Glucose Do Not Match: How Much Is Determined by Race, by Genetics, by Differences in Mean Red Blood Cell Age? The Journal of clinical endocrinology and metabolism, 104 3, 707-710

Klonoff, David C; Aron, David; Cohen, Robert M; Home, Philip; John, W Garry; Little, Randie R; Nathan, David M; Sacks, David B 2019. The Need for Accuracy in Hemoglobin A1c Proficiency Testing: Why the Proposed CLIA Rule of 2019 Is a Step Backward. Journal of diabetes science and technology, 13 3, 424-427

Larkin, Mary E; Nathan, David M; Bebu, Ionut; Krause-Steinrauf, Heidi; Herman, William H; Higgins, John M; Tiktin, Margaret; Cohen, Robert M; Lund, Claire; Bergenstal, Richard M; Johnson, Mary L; Arends, Valerie 2019. Rationale and Design for a GRADE Substudy of Continuous Glucose Monitoring. Diabetes technology & therapeutics, 21 12, 682-690

Morris, Mackenzie C; Jung, Andrew D; Kim, Young; Lee, Tiffany C; Kaiser, Tiffany E; Thompson, Jonathan R; Bari, Khurram; Shah, Shimul A; Cohen, Robert M; Schauer, Daniel P; Smith, Eric P; Diwan, Tayyab S 2019. Delayed Sleeve Gastrectomy Following Liver Transplantation: A 5-Year Experience. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 25 11, 1673-1681

Angellotti, Edith; D'Alessio, David; Dawson-Hughes, Bess; Nelson, Jason; Cohen, Robert M; Gastaldelli, Amalia; Pittas, Anastassios G 2018. Vitamin D Supplementation in Patients With Type 2 Diabetes: The Vitamin D for Established Type 2 Diabetes (DDM2) Study. Journal of the Endocrine Society, 2 4, 310-321

Freedman, Barry I; Sink, Kaycee M; Hugenschmidt, Christina E; Hughes, Timothy M; Williamson, Jeff D; Whitlow, Christopher T; Palmer, Nicholette D; Miller, Michael E; Lovato, Laura C; Xu, Jianzhao; Smith, S Carrie; Launer, Lenore J; Barzilay, Joshua I; Cohen, Robert M; Sullivan, Mark D; Bryan, R Nick; Wagner, Benjamin C; Bowden, Donald W; Maldjian, Joseph A; Divers, Jasmin 2017. Associations of Early Kidney Disease With Brain Magnetic Resonance Imaging and Cognitive Function in African Americans With Type 2 Diabetes Mellitus. American journal of kidney diseases : the official journal of the National Kidney Foundation, ,

Schmidt, Robert L; Mock, Donald M; Franco, Robert S; Cohen, Robert M; North, Anne K; Cancelas, José A; Geisen, Christof; Strauss, Ronald G; Vlaar, Alexander P; Nalbant, Demet; Widness, John A 2017. Antibodies to biotinylated red blood cells in adults and infants: improved detection, partial characterization, and dependence on red blood cell-biotin dose. Transfusion, 57 6, 1488-1496

Cohen, Robert M; Franco, Robert S 2016. Can Red Blood Cell Indices Act as Surrogate Markers for Discordance between Hemoglobin A1c and Fasting Blood Glucose? Clinical chemistry, 62 12, 1551-1553

Cohen, Robert M; Smith, Eric P; Arbabi, Shahriar; Quinn, Charles T; Franco, Robert S 2016. Do Red Blood Cell Indices Explain Racial Differences in the Relationship between Hemoglobin A1c and Blood Glucose? The Journal of pediatrics, 176 , 7-9

Quinn, Charles T; Smith, Eric P; Arbabi, Shahriar; Khera, Paramjit K; Lindsell, Christopher J; Niss, Omar; Joiner, Clinton H; Franco, Robert S; Cohen, Robert M 2016. Biochemical surrogate markers of hemolysis do not correlate with directly measured erythrocyte survival in sickle cell anemia. American journal of hematology, 91 12, 1195-1201

Drake, T C; Hsu, F-C; Hire, D; Chen, S-H; Cohen, R M; McDuffie, R; Nylen, E; O'Connor, P; Rehman, S; Seaquist, E R 2015. Factors associated with failure to achieve a glycated haemoglobin target of <8.0% in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial. Diabetes, obesity & metabolism, ,

Inge, Thomas H; Prigeon, Ronald L; Elder, Deborah A; Jenkins, Todd M; Cohen, Robert M; Xanthakos, Stavra A; Benoit, Stephen C; Dolan, Lawrence M; Daniels, Stephen R; D'Alessio, David A 2015. Insulin Sensitivity and ?-Cell Function Improve after Gastric Bypass in Severely Obese Adolescents. The Journal of pediatrics, 167 5, 1042-1048.e1

Khera, Paramjit K; Smith, Eric P; Lindsell, Christopher J; Rogge, Mary Colleen; Haggerty, Shannon; Wagner, David A; Palascak, Mary B; Mehta, Shilpa; Hibbert, Jacqueline M; Joiner, Clinton H; Franco, Robert S; Cohen, Robert M 2015. Use of an oral stable isotope label to confirm variation in red blood cell mean age that influences HbA1c interpretation. American journal of hematology, 90 1, 50-5

Lewis, Julia B; Sika, Mohammed; Koury, Mark J; Chuang, Peale; Schulman, Gerald; Smith, Mark T; Whittier, Frederick C; Linfert, Douglas R; Galphin, Claude M; Athreya, Balaji P; Nossuli, A Kaldun Kaldun; Chang, Ingrid J; Blumenthal, Samuel S; Manley, John; Zeig, Steven; Kant, Kotagal S; Olivero, Juan Jose; Greene, Tom; Dwyer, Jamie P 2015. Ferric citrate controls phosphorus and delivers iron in patients on dialysis. Journal of the American Society of Nephrology : JASN, 26 2, 493-503

Papademetriou, Vasilios; Lovato, Laura; Doumas, Michael; Nylen, Eric; Mottl, Amy; Cohen, Robert M; Applegate, William B; Puntakee, Zubin; Yale, Jean Francois; Cushman, William C 2015. Chronic kidney disease and intensive glycemic control increase cardiovascular risk in patients with type 2 diabetes. Kidney international, 87 3, 649-59

Schwartz, Ann V; Chen, Haiying; Ambrosius, Walter T; Sood, Ajay; Josse, Robert G; Bonds, Denise E; Schnall, Adrian M; Vittinghoff, Eric; Bauer, Douglas C; Banerji, Mary Ann; Cohen, Robert M; Hamilton, Bruce P; Isakova, Tamara; Sellmeyer, Deborah E; Simmons, Debra L; Shibli-Rahhal, Amal; Williamson, Jeff D; Margolis, Karen L 2015. Effects of TZD Use and Discontinuation on Fracture Rates in ACCORD Bone Study. The Journal of clinical endocrinology and metabolism, 100 11, 4059-66

Smith, Eric P; Cohen, Robert M 2015. Physiologic Concepts That May Revise the Interpretation and Implications of HbA1C in Clinical Medicine: An American Perspective. Journal of diabetes science and technology, 9 3, 696-700

Cohen RM and Herman WH 2014. Are glycated serum proteins ready for prime time? The Lancet Diabetes & Endocrinology (Invited Commentary), 2 4, 264

Cohen, Robert M; Herman, William H 2014. Are glycated serum proteins ready for prime time? The lancet. Diabetes & endocrinology, 2 4, 264-5

Karen L. Margolis, Patrick J. O’Connor, Timothy M. Morgan, John Buse, Robert Cohen, William C. Cushman, Jeffrey A. Cutler, Greg Evans, Hertzel Gerstein, Richard H. Grimm Jr, Edward Lipkin, K.M. Venkat Narayan, Matthew C. Riddle, Denise Simons-Morton, Ajay Sood, David C. Goff Jr. 2014. Outcomes of Combined Cardiovascular Risk Factor Management Strategies in Type 2 Diabetes Mellitus: The ACCORD Trial Diabetes Care , ,

Margolis, Karen L; O'Connor, Patrick J; Morgan, Timothy M; Buse, John B; Cohen, Robert M; Cushman, William C; Cutler, Jeffrey A; Evans, Gregory W; Gerstein, Hertzel C; Grimm, Richard H; Lipkin, Edward W; Narayan, K M Venkat; Riddle, Matthew C; Sood, Ajay; Goff, David C 2014. Outcomes of combined cardiovascular risk factor management strategies in type 2 diabetes: the ACCORD randomized trial. Diabetes care, 37 6, 1721-8

Mock DM, Widness JA, Veng-Pedersen P, Strauss RG, Cancelas JA, Cohen RM, Lindsell CJ, Franco RS. 2014. Measurement of Post-Transfusion Red Cell Survival with the Biotin Label Transfusion Reviews, ,

Mock, Donald M; Widness, John A; Veng-Pedersen, Peter; Strauss, Ronald G; Cancelas, Jose A; Cohen, Robert M; Lindsell, Christopher J; Franco, Robert S 2014. Measurement of Posttransfusion Red Cell Survival With the Biotin Label. Transfusion medicine reviews, 28 3, 114-125

Paramjit K. Khera, Eric P. Smith, Christopher J. Lindsell, M. Colleen Rogge, Shannon Haggerty, David A. Wagner, Mary B. Palascak, Shilpa Mehta, Jacqueline M. Hibbert, Clinton H. Joiner, Robert S. Franco, Robert M. Cohen 2014. An oral stable isotope label confirms red blood cell mean age varies among individuals and influences HbA1c interpretation , ,

Vasilios Papademetriou, Laura Lovato, Michael Doumas, Eric Nylen, Amy Mottl, Robert M Cohen, Bill Applegate, Zubin Puntakee, Gillian Booth, Jean Francois Yale, William Cushman; for the ACCORD Study Group 2014. The impact of chronic kidney disease and intensive glycemic control on cardiovascular outcomes in patients with type 2 diabetes. , ,

Fonseca V, McDuffie R, Calles J, Cohen RM, Feeney P, Feinglos M, Gerstein H, Ismail Beigi F, Morgan TM, Pop-Busui R, Riddle Matthew C and the ACCORD study group. 2013. Determinants of Weight Gain in the ACCORD Trial Diabetes Care, 36, 2162-2168

Barzilay, Joshua I; Howard, Annie G; Evans, Gregory W; Fleg, Jerome L; Cohen, Robert M; Booth, Gillian L; Kimel, Angela R; Pedley, Carolyn F; Cushman, William C 2012. Intensive Blood Pressure Treatment Does Not Improve Cardiovascular Outcomes in Centrally Obese Hypertensive Individuals With Diabetes: The Action to Control Cardiovascular Risk in Diabetes (ACCORD) Blood Pressure Trial Diabetes Care, 35 7, 1401-5

Cohen RM and Lindsell CJ 2012. When the Blood Glucoses and the A1c Don’t Match: Turning Uncertainty into Opportunity. Diabetes Care , 35, 2421-2423

Cohen RM and Sacks DB 2012. Comparing Multiple Measures of Glycemia: How to Transitionfrom Biomarker to Diagnostic Test Clinical Chemistry, 58, 1615-1617

Cohen, Robert M; Lindsell, Christopher J 2012. When the blood glucose and the HbA(1c) don't match: turning uncertainty into opportunity. Diabetes care, 35 12, 2421-3

Herman, William H; Cohen, Robert M 2012. Racial and Ethnic Differences in the Relationship between HbA1c and Blood Glucose: Implications for the Diagnosis of Diabetes The Journal of Clinical Endocrinology and Metabolism, 97 4, 1067-72

Joshua I. Barzilay , Annie G. Howard, Gregory W. Evans, Jerome L. Fleg, Robert M. Cohen, Gillian L. Booth, MD, Angela R. Kimel, Carolyn F. Pedley, William C. Cushman 2012. Intensive Blood Pressure Treatment Does Not Improve Cardiovascular Outcomes in Centrally Obese Hypertensive Individuals With Diabetes: The Action to Control Cardiovascular Risk in Diabetes Diabetes Care , 35, 1401-1405

Robert S. Franco, M. Estela Campanella, Latorya A. Barber, Mary B. Palascak, Clinton H. Joiner, Philip S. Low, and Robert M. Cohen. 2012. Changes in the Properties of Normal Human Red Blood Cells during In Vivo Aging. American J Hematology, 88, 44-51

Robert S. Franco, M. Estela Campanella, Latorya A. Barber, Mary B. Palascak, Clinton H. Joiner, Philip S. Low, and Robert M. Cohen. 2012. Changes in the Properties of Normal Human Red Blood Cells during In Vivo Aging. American J Hematology, 88, 44-51

Gerstein, Hertzel C; Miller, Michael E; Genuth, Saul; Ismail-Beigi, Faramarz; Buse, John B; Goff, David C; Probstfield, Jeffrey L; Cushman, William C; Ginsberg, Henry N; Bigger, J Thomas; Grimm, Richard H; Byington, Robert P; Rosenberg, Yves D; Friedewald, William T 2011. Long-term effects of intensive glucose lowering on cardiovascular outcomes The New England Journal of Medicine, 364 9, 818-28

, ; Cushman, William C; Evans, Gregory W; Byington, Robert P; Goff, David C; Grimm, Richard H; Cutler, Jeffrey A; Simons-Morton, Denise G; Basile, Jan N; Corson, Marshall A; Probstfield, Jeffrey L; Katz, Lois; Peterson, Kevin A; Friedewald, William T; Buse, John B; Bigger, J Thomas; Gerstein, Hertzel C; Ismail-Beigi, Faramarz 2010. Effects of intensive blood-pressure control in type 2 diabetes mellitus. The New England journal of medicine, 362 17, 1575-85

ACCORD Study Group, Ginsberg HN, Elam MB, Lovato LC, Crouse JR 3rd, Leiter LA, Linz P, Friedewald WT, Buse JB, Gerstein HC, Probstfield J, Grimm RH, Ismail-Beigi F, Bigger JT, Goff DC Jr, Cushman WC, Simons-Morton DG, Byington RP 2010. Effects of combination lipid therapy in type 2 diabetes mellitus The New England Journal of Medicine, 362 17, 1563-74

ACCORD Study Group; ACCORD Eye Study Group, Chew EY, Ambrosius WT, Davis MD, Danis RP, Gangaputra S, Greven CM, Hubbard L, Esser BA, Lovato JF, Perdue LH, Goff DC Jr, Cushman WC, Ginsberg HN, Elam MB, Genuth S, Gerstein HC, Schubart U, Fine LJ. 2010. Effects of medical therapies on retinopathy progression in type 2 diabetes The New England Journal of Medicine, 363 3, 233-44

Ambrosius, Walter T; Danis, Ronald P; Goff, David C; Greven, Craig M; Gerstein, Hertzel C; Cohen, Robert M; Riddle, Matthew C; Miller, Michael E; Buse, John B; Bonds, Denise E; Peterson, Kevin A; Rosenberg, Yves D; Perdue, Letitia H; Esser, Barbara A; Seaquist, Lea A; Felicetta, James V; Chew, Emily Y 2010. Lack of association between thiazolidinediones and macular edema in type 2 diabetes: the ACCORD eye substudy Archives of Ophthalmology, 128 3, 312-8

Calles-Escandón, Jorge; Lovato, Laura C; Simons-Morton, Denise G; Kendall, David M; Pop-Busui, Rodica; Cohen, Robert M; Bonds, Denise E; Fonseca, Vivian A; Ismail-Beigi, Faramarz; Banerji, Mary Ann; Failor, Alan; Hamilton, Bruce 2010. Effect of intensive compared with standard glycemia treatment strategies on mortality by baseline subgroup characteristics: the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial. Diabetes care, 33 4, 721-7

Cohen, Robert M; Haggerty, Shannon; Herman, William H 2010. HbA1c for the diagnosis of diabetes and prediabetes: is it time for a mid-course correction? The Journal of Clinical Endocrinology and Metabolism, 95 12, 5203-6

Herman, William H; Cohen, Robert M 2010. Hemoglobin A1c: teaching a new dog old tricks Annals of Internal Medicine, 152 12, 815-7

Ismail-Beigi, Faramarz; Craven, Timothy; Banerji, Mary Ann; Basile, Jan; Calles, Jorge; Cohen, Robert M; Cuddihy, Robert; Cushman, William C; Genuth, Saul; Grimm, Richard H; Hamilton, Bruce P; Hoogwerf, Byron; Karl, Diane; Katz, Lois; Krikorian, Armand; O 2010. Effect of intensive treatment of hyperglycaemia on microvascular outcomes in type 2 diabetes: an analysis of the ACCORD randomised trial Lancet, 376 9739, 419-30

Riddle, Matthew C; Ambrosius, Walter T; Brillon, David J; Buse, John B; Byington, Robert P; Cohen, Robert M; Goff, David C; Malozowski, Saul; Margolis, Karen L; Probstfield, Jeffrey L; Schnall, Adrian; Seaquist, Elizabeth R 2010. Epidemiologic relationships between A1C and all-cause mortality during a median 3.4-year follow-up of glycemic treatment in the ACCORD trial Diabetes Care, 33 5, 983-90

Leslie, R David G; Cohen, Robert M 2009. Biologic variability in plasma glucose, hemoglobin A1c, and advanced glycation end products associated with diabetes complications. Journal of diabetes science and technology, 3 4, 635-43

, ; Gerstein, Hertzel C; Miller, Michael E; Byington, Robert P; Goff, David C; Bigger, J Thomas; Buse, John B; Cushman, William C; Genuth, Saul; Ismail-Beigi, Faramarz; Grimm, Richard H; Probstfield, Jeffrey L; Simons-Morton, Denise G; Friedewald, William T 2008. Effects of intensive glucose lowering in type 2 diabetes. The New England journal of medicine, 358 24, 2545-59

Cohen, Robert M; Franco, Robert S; Khera, Paramjit K; Smith, Eric P; Lindsell, Christopher J; Ciraolo, Peter J; Palascak, Mary B; Joiner, Clinton H 2008. Red cell life span heterogeneity in hematologically normal people is sufficient to alter HbA1c. Blood, 112 10, 4284-91

Cohen, Robert M; Joiner, Clinton H; Franco, Robert S 2008. Discordant HbA1c results: the hoofbeats increase. The Journal of pediatrics, 153 1, 7-9

Cohen, Robert M; LeCaire, Tamara J; Lindsell, Christopher J; Smith, Eric P; D'Alessio, Donn J 2008. Relationship of prospective GHb to glycated serum proteins in incident diabetic retinopathy: implications of the glycation gap for mechanism of risk prediction. Diabetes care, 31 1, 151-3

Cohen, Robert M; Smith, Eric P 2008. Frequency of HbA1c discordance in estimating blood glucose control. Current opinion in clinical nutrition and metabolic care, 11 4, 512-7

El Khoury, Marc; Yousuf, Farheen; Martin, Vincent; Cohen, Robert M 2008. Pseudohypoglycemia: a cause for unreliable finger-stick glucose measurements. Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 14 3, 337-9

Khera, Paramjit K; Joiner, Clinton H; Carruthers, Anthony; Lindsell, Christopher J; Smith, Eric P; Franco, Robert S; Holmes, Yancey R; Cohen, Robert M 2008. Evidence for interindividual heterogeneity in the glucose gradient across the human red blood cell membrane and its relationship to hemoglobin glycation. Diabetes, 57 9, 2445-52

Lindsell, Christopher J; Franco, Robert S; Smith, Eric P; Joiner, Clinton H; Cohen, Robert M 2008. A method for the continuous calculation of the age of labeled red blood cells. American journal of hematology, 83 6, 454-7

Smith, Eric P; Specker, Bonny; Bachrach, Bert E; Kimbro, K S; Li, X J; Young, Marian F; Fedarko, Neal S; Abuzzahab, M J; Frank, Graeme R; Cohen, Robert M; Lubahn, Dennis B; Korach, Kenneth S 2008. Impact on bone of an estrogen receptor-alpha gene loss of function mutation. The Journal of clinical endocrinology and metabolism, 93 8, 3088-96

Cohen, Robert M 2007. A1C: does one size fit all? Diabetes care, 30 10, 2756-8

Gerstein, Hertzel C; Riddle, Matthew C; Kendall, David M; Cohen, Robert M; Goland, Robin; Feinglos, Mark N; Kirk, Julienne K; Hamilton, Bruce P; Ismail-Beigi, Faramarz; Feeney, Patricia 2007. Glycemia treatment strategies in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial. The American journal of cardiology, 99 12A, 34i-43i

Cohen, Robert M; Snieder, Harold; Lindsell, Christopher J; Beyan, Huriya; Hawa, Mohammed I; Blinko, Stuart; Edwards, Raymond; Spector, Timothy D; Leslie, R David G 2006. Evidence for independent heritability of the glycation gap (glycosylation gap) fraction of HbA1c in nondiabetic twins. Diabetes care, 29 8, 1739-43

Dolan, Lawrence M; Bean, Judy; D'Alessio, David; Cohen, Robert M; Morrison, John A; Goodman, Elizabeth; Daniels, Stephen R 2005. Frequency of abnormal carbohydrate metabolism and diabetes in a population-based screening of adolescents. The Journal of pediatrics, 146 6, 751-8

Schulze, M B; Solomon, C G; Rifai, N; Cohen, R M; Sparrow, J; Hu, F B; Manson, J E 2005. Hyperproinsulinaemia and risk of Type 2 diabetes mellitus in women. Diabetic medicine : a journal of the British Diabetic Association, 22 9, 1178-84

Cohen, Robert M; Franco, Robert S; Joiner, Clinton H 2004. Is poor glycemic control associated with reduced red blood cell lifespan? Diabetes care, 27 4, 1013-4

Klein, David J; Aronson Friedman, Lisa; Harlan, William R; Barton, Bruce A; Schreiber, George B; Cohen, Robert M; Harlan, Linda C; Morrison, John A 2004. Obesity and the development of insulin resistance and impaired fasting glucose in black and white adolescent girls: a longitudinal study. Diabetes care, 27 2, 378-83

Cohen, Robert M; Holmes, Yancey R; Chenier, Thomas C; Joiner, Clinton H 2003. Discordance between HbA1c and fructosamine: evidence for a glycosylation gap and its relation to diabetic nephropathy. Diabetes care, 26 1, 163-7

Cohen, Robert M; Ramlo-Halsted, Barbara A 2002. How do the new insulin secretagogues compare? Diabetes care, 25 8, 1472-3

Cohen, R M 2000. Implications of linking pharmacy and laboratory data to assess diabetes care. Diabetes care, 23 11, 1603-4

Nikiforova, M N; Nikiforov, Y E; Biddinger, P; Gnepp, D R; Grosembacher, L A; Wajchenberg, B L; Fagin, J A; Cohen, R M 1999. Frequent loss of heterozygosity at chromosome 3p14.2-3p21 in human pancreatic islet cell tumours. Clinical endocrinology, 51 1, 27-33

Pinhas-Hamiel, O; Standiford, D; Hamiel, D; Dolan, L M; Cohen, R; Zeitler, P S 1999. The type 2 family: a setting for development and treatment of adolescent type 2 diabetes mellitus. Archives of pediatrics & adolescent medicine, 153 10, 1063-7

Tiao, G M; Martin, J; Weber, F L; Cohen, R M; Hanto, D W 1999. Addisonian crisis in a liver transplant patient due to fluconazole withdrawal. Clinical transplantation, 13 1 Pt 1, 62-4

Tam, E S; Ferguson, D G; Bielefeld, D R; Lorenz, J N; Cohen, R M; Pun, R Y 1997. Norepinephrine-mediated calcium signaling is altered in vascular smooth muscle of diabetic rat. Cell calcium, 21 2, 143-50

Bernstein, D I; Creticos, P S; Busse, W W; Cohen, R; Graft, D F; Howland, W C; Lumry, W R; Pedinoff, A J; Ratner, P H; Lim, J; Stokes, A; McNally, C 1996. Comparison of triamcinolone acetonide nasal inhaler with astemizole in the treatment of ragweed-induced allergic rhinitis. The Journal of allergy and clinical immunology, 97 3, 749-55

Chiasson, J L; Josse, R G; Leiter, L A; Mihic, M; Nathan, D M; Palmason, C; Cohen, R M; Wolever, T M 1996. The effect of acarbose on insulin sensitivity in subjects with impaired glucose tolerance. Diabetes care, 19 11, 1190-3

Katz, R J; Ratner, R E; Cohen, R M; Eisenhower, E; Verme, D 1996. Are insulin and proinsulin independent risk markers for premature coronary artery disease ? Diabetes, 45 6, 736-41

Klein, D J; Cohen, R M; Rymaszewski, Z 1995. Proteoglycan synthesis by bovine myocardial endothelial cells is increased by long-term exposure to high concentrations of glucose. Journal of cellular physiology, 165 3, 493-502

Klonoff, D C; Barrett, B J; Nolte, M S; Cohen, R M; Wyderski, R 1995. Hypoglycemia following inadvertent and factitious sulfonylurea overdosages. Diabetes care, 18 4, 563-7

Smith, E P; Boyd, J; Frank, G R; Takahashi, H; Cohen, R M; Specker, B; Williams, T C; Lubahn, D B; Korach, K S 1994. Estrogen resistance caused by a mutation in the estrogen-receptor gene in a man. The New England journal of medicine, 331 16, 1056-61

Cohen, R M; Nathan, D M; Clements, R S 1992. Hyperproinsulinemia in type II diabetes. Diabetes care, 15 5, 723-4

Rymaszewski, Z; Szymanski, P T; Abplanalp, W A; Myatt, L; Di Salvo, J; Cohen, R M 1992. Human retinal vascular cells differ from umbilical cells in synthetic functions and their response to glucose. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 199 2, 183-91

Arshad, M A; Bhadra, S; Cohen, R M; Subbiah, M T 1991. Plasma lipoprotein peroxidation potential: a test to evaluate individual susceptibility to peroxidation. Clinical chemistry, 37 10 Pt 1, 1756-8

Cohen, R M; Abplanalp, W A 1991. Resistance of growth hormone secretion to somatostatin in men with type I diabetes mellitus. Diabetes, 40 10, 1251-8

Rymaszewski, Z; Cohen, R M; Chomczynski, P 1991. Human growth hormone stimulates proliferation of human retinal microvascular endothelial cells in vitro. Proceedings of the National Academy of Sciences of the United States of America, 88 2, 617-21

Camus-Bablon, F; Cohen, R M; Berk, M A; Perisutti, G; Hunter, K; Frohman, L A 1990. Alterations in circulating human chorionic gonadotropin free alpha-subunit in insulin-dependent diabetic pregnancy: correlation with maternal characteristics. The Journal of clinical endocrinology and metabolism, 71 1, 46-52

Menon, R K; Cohen, R M; Sperling, M A; Cutfield, W S; Mimouni, F; Khoury, J C 1990. Transplacental passage of insulin in pregnant women with insulin-dependent diabetes mellitus. Its role in fetal macrosomia. The New England journal of medicine, 323 5, 309-15

Rymaszewski, Z; Abplanalp, W A; Cohen, R M; Chomczynski, P 1990. Estimation of cellular DNA content in cell lysates suitable for RNA isolation. Analytical biochemistry, 188 1, 91-6

Cohen, R M; Camus, F 1988. Update on insulinomas or the case of the missing (pro)insulinoma. Diabetes care, 11 6, 506-8

Cohen, R M; Licinio, J; Polonsky, K S; Galloway, J A; Frank, B H; Cherrington, A D; Rubenstein, A H 1987. The effect of biosynthetic human proinsulin on the hepatic response to glucagon in insulin-deficient diabetes. The Journal of clinical endocrinology and metabolism, 64 3, 476-81

Glauber, H S; Henry, R R; Wallace, P; Frank, B H; Galloway, J A; Cohen, R M; Olefsky, J M 1987. The effects of biosynthetic human proinsulin on carbohydrate metabolism in non-insulin-dependent diabetes mellitus. The New England journal of medicine, 316 8, 443-9

Rosenfield, R L; Cohen, R M; Talerman, A 1987. Lipid cell tumor of the ovary in reference to adult-onset congenital adrenal hyperplasia and polycystic ovary syndrome. A case report. The Journal of reproductive medicine, 32 5, 363-9

Cohen, R M; Given, B D; Licinio-Paixao, J; Provow, S A; Rue, P A; Frank, B H; Root, M A; Polonsky, K S; Tager, H S; Rubenstein, A H 1986. Proinsulin radioimmunoassay in the evaluation of insulinomas and familial hyperproinsulinemia. Metabolism: clinical and experimental, 35 12, 1137-46

Glauber, H S; Revers, R R; Henry, R; Schmeiser, L; Wallace, P; Kolterman, O G; Cohen, R M; Rubenstein, A H; Galloway, J A; Frank, B H 1986. In vivo deactivation of proinsulin action on glucose disposal and hepatic glucose production in normal man. Diabetes, 35 3, 311-7

Cohen, R M; Nakabayashi, T; Blix, P M; Rue, P A; Shoelson, S E; Root, M A; Frank, B H; Revers, R R; Rubenstein, A H 1985. A radioimmunoassay for circulating human proinsulin. Diabetes, 34 1, 84-91

Given, B D; Cohen, R M; Shoelson, S E; Frank, B H; Rubenstein, A H; Tager, H S 1985. Biochemical and clinical implications of proinsulin conversion intermediates. The Journal of clinical investigation, 76 4, 1398-405

Herold, K C; Polonsky, K S; Cohen, R M; Levy, J; Douglas, F 1985. Variable deterioration in cortical function during insulin-induced hypoglycemia. Diabetes, 34 7, 677-85

Bergenstal, R M; Cohen, R M; Lever, E; Polonsky, K; Jaspan, J; Blix, P M; Revers, R; Olefsky, J M; Kolterman, O; Steiner, K 1984. The metabolic effects of biosynthetic human proinsulin in individuals with type I diabetes. The Journal of clinical endocrinology and metabolism, 58 6, 973-9

Kruse, V; Heding, L G; Jørgensen, K H; Tronier, B; Christensen, M; Thim, L; Frank, B H; Root, M A; Cohen, R M; Rubenstein, A H 1984. Human proinsulin standards. Diabetologia, 27 3, 414-5

Revers, R R; Henry, R; Schmeiser, L; Kolterman, O; Cohen, R; Bergenstal, R; Polonsky, K; Jaspan, J; Rubenstein, A; Frank, B 1984. The effects of biosynthetic human proinsulin on carbohydrate metabolism. Diabetes, 33 8, 762-70

Revers, R R; Henry, R; Schmeiser, L; Kolterman, O; Cohen, R; Rubenstein, A; Frank, B; Galloway, J; Olefsky, J M 1984. Biosynthetic human insulin and proinsulin have additive but not synergistic effects on total body glucose disposal. The Journal of clinical endocrinology and metabolism, 58 6, 1094-8

Madsen, O D; Cohen, R M; Fitch, F W; Rubenstein, A H; Steiner, D F 1983. The production and characterization of monoclonal antibodies specific for human proinsulin using a sensitive microdot assay procedure. Endocrinology, 113 6, 2135-44

Ginsberg, B H; Cohen, R M; Kahn, C R; Roth, J 1978. Properties and partial purification of the detergent-solubilized insulin receptor: a demonstration of negative cooperativity in micellar solution. Biochimica et biophysica acta, 542 1, 88-100

Margolis, David J; Hoffstad, Ole; Thom, Stephen; Bilker, Warren; Maldonado, Arturo R; Cohen, Robert M; Aronow, Bruce J; Crombleholme, Timothy . The differential effect of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers with respect to foot ulcer and limb amputation in those with diabetes. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society, 18 5, 445-51