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Photo of  Amy Makley, MD

Amy Makley, MD

Associate Professor of Clinical

Director of Trauma, UC Medical Center; Associate Director, Residency Program in General Surgery

COM Surgery Trauma & Critical Care

Education/Credentials
  • Bachelor's Degree: University of Dayton
  • Medical Degree: University of Cincinnati
  • Research Fellowship: University of Cincinnati
  • General Surgery Residency: University of Cincinnati
  • Fellowship in Surgical Critical Care: University of Pennsylvania
Board Certifications & Licenses

American Board of Surgery (Surgery Critical Care) (Certification Date: 09/23/2013)
American Board of Surgery (Certification Date: 03/18/2013)

Clinical Interest

Critical Care Surgery
General Surgery

Specialties

Surgery
Surgery-Critical Care

Research Interests

General Surgery, Trauma Surgery, Acute Care Surgery, Hemorrhagic Shock

Contact Information
  • Medical Sciences Building
  • SRU Room 1577
  • 231 Albert Sabin Way
  • Cincinnati, Ohio 45267
  • Office 513-558-5861
  • Email amy.makley@uc.edu

Peer Reviewed Publications

Kassam, Al-Faraaz; Cortez, Alexander R; Winer, Leah K; Baker, Jennifer E; Hanseman, Dennis J; Wells, Dennis; Yalamanchili, Suma; Habashy, Engy; Chausse, Steve; Makley, Amy T; Goodman, Michael D; Sussman, Jeffrey J; Quillin, Ralph C 2020. Swipe right for surgical residency: Exploring the unconscious bias in resident selection. Surgery, ,

Kassam, Al-Faraaz; Singer, Kathleen E; Winer, Leah K; Browne, Deborah; Sussman, Jeffrey J; Goodman, Michael D; Makley, Amy T 2020. Acquisition and retention of surgical skills taught during intern surgical boot camp. American journal of surgery, ,

Morris, Mackenzie C; John, Devin; Singer, Kathleen E; Moran, Ryan; McGlone, Emily; Veile, Rosalie; Goetzman, Holly S; Makley, Amy T; Caldwell, Charles C; Goodman, Michael D 2020. Post-TBI splenectomy may exacerbate coagulopathy and platelet activation in a murine model. Thrombosis research, 193 , 211-217

Morris, Mackenzie C; Niziolek, Grace M; Baker, Jennifer E; Huebner, Benjamin R; Hanseman, Dennis; Makley, Amy T; Pritts, Timothy A; Goodman, Michael D 2020. Death by Decade: Establishing a Transfusion Ceiling for Futility in Massive Transfusion. The Journal of surgical research, 252 , 139-146

Niziolek, Grace M; Boudreau, Ryan M; Baker, Jennifer; Friend, Lou Ann; Makley, Amy T; Edwards, Michael J; Gulbins, Erich; Goodman, Michael D 2020. Acid Sphingomyelinase Inhibition Mitigates Histopathological and Behavioral Changes in a Murine Model of Traumatic Brain Injury. Journal of neurotrauma, 37 17, 1902-1909

Pulliam, Kasiemobi E; Joseph, Bernadin; Makley, Amy T; Caldwell, Charles C; Lentsch, Alex B; Goodman, Michael D; Pritts, Timothy A 2020. Washing packed red blood cells decreases red blood cell storage lesion formation. Surgery, ,

Pulliam, Kasiemobi E; Joseph, Bernadin; Morris, Mackenzie C; Veile, Rosalie A; Schuster, Rebecca M; Makley, Amy T; Pritts, Timothy A; Goodman, Michael D 2020. Innate coagulability changes with age in stored packed red blood cells. Thrombosis research, 195 , 35-42

Pulliam, Kasiemobi E; Joseph, Bernadin; Veile, Rosalie A; Friend, Lou Ann; Makley, Amy T; Caldwell, Charles C; Lentsch, Alex B; Goodman, Michael D; Pritts, Timothy A 2020. Expired But Not Yet Dead: Examining the Red Blood Cell Storage Lesion in Extended-Storage Whole Blood. Shock (Augusta, Ga.), ,

Pulliam, Kasiemobi E; Joseph, Bernadin; Veile, Rosalie A; Friend, Lou Ann; Makley, Amy T; Caldwell, Charles C; Lentsch, Alex B; Goodman, Michael D; Pritts, Timothy A 2020. SAVE IT - DON'T WASTE IT! MAXIMIZING UTILIZATION OF ERYTHROCYTES FROM PREVIOUSLY STORED WHOLE BLOOD. The journal of trauma and acute care surgery, ,

Singer, Kathleen E; Morris, Mackenzie C; Blakeman, Christopher; Stevens-Topie, Sabre M; Veile, Rosalie; Fortuna, Gerald; DuBose, Joseph J; Stuever, Mary F; Makley, Amy T; Goodman, Michael D 2020. Can Resuscitative Endovascular Balloon Occlusion of the Aorta Fly? Assessing Aortic Balloon Performance for Aeromedical Evacuation. The Journal of surgical research, 254 , 390-397

Wagner, Monica L; Farooqui, Zishaan; Elson, Nora C; Makley, Amy T; Pritts, Timothy A; Goodman, Michael D 2020. Characterizing Early Inpatient Death After Trauma. The Journal of surgical research, 255 , 405-410

Wagner, Monica L; Streit, Stephanie; Makley, Amy T; Pritts, Timothy A; Goodman, Michael D 2020. Hepatic Pseudoaneurysm Incidence After Liver Trauma. The Journal of surgical research, 256 , 623-628

Baker, Jennifer E; Niziolek, Grace M; Elson, Nora C; Pugh, Amanda M; Nomellini, Vanessa; Makley, Amy T; Pritts, Timothy A; Goodman, Michael D 2019. Optimizing Lower Extremity Duplex Ultrasound Screening After Traumatic Injury. The Journal of surgical research, 243 , 143-150

Boudreau, Ryan M; Deshpande, Keshav K; Day, Gregory M; Hinckley, William R; Harger, Nicole; Pritts, Timothy A; Makley, Amy T; Goodman, Michael D 2019. Prehospital Tranexamic Acid Administration During Aeromedical Transport After Injury. The Journal of surgical research, 233 , 132-138

Kassam, Al-Faraaz; Cortez, Alexander R; Diwan, Tayyab S; Bailey, Amanda; Mirza, Ahmad; Sussman, Jeffrey J; Makley, Amy T; Quillin, Ralph Cutler 2019. Return to the Real World: A Novel Program to Improve Resident Readiness for the Transplant Surgery Rotation. Journal of surgical education, ,

Martin, Grace E; Johnson, Mark; Veile, Rose; Friend, Lou Ann; Elterman, Joel B; Johannigman, Jay A; Pritts, Timothy A; Goodman, Michael D; Makley, Amy T 2019. Effects of Early Altitude Exposure on the Open Abdomen After Laparotomy in Trauma. Military medicine, ,

Martin, Grace E; Pugh, Amanda M; Moran, Ryan; Veile, Rose; Friend, Lou Ann; Pritts, Timothy A; Makley, Amy T; Caldwell, Charles C; Goodman, Michael D 2019. Microvesicles generated following traumatic brain injury induce platelet dysfunction via adenosine diphosphate receptor. The journal of trauma and acute care surgery, 86 4, 592-600

Martin, Grace E; Pugh, Amanda; Williams, Susan G; Hanseman, Dennis; Nomellini, Vanessa; Makley, Amy T; Pritts, Timothy A; Goodman, Michael D 2019. Lower Extremity Duplex Ultrasound Screening Protocol for Moderate- and High-Risk Trauma Patients. The Journal of surgical research, 235 , 280-287

Morris, Mackenzie C; Bercz, Aron; Niziolek, Grace M; Kassam, Farzaan; Veile, Rose; Friend, Lou Ann; Pritts, Timothy A; Makley, Amy T; Goodman, Michael D 2019. UCH-L1 is a Poor Serum Biomarker of Murine Traumatic Brain Injury After Polytrauma. The Journal of surgical research, 244 , 63-68

Morris, Mackenzie C; Kassam, Farzaan; Bercz, Aron; Beckmann, Nadine; Schumacher, Fabian; Gulbins, Erich; Makley, Amy T; Goodman, Michael D 2019. The Role of Chemoprophylactic Agents in Modulating Platelet Aggregability After Traumatic Brain Injury. The Journal of surgical research, 244 , 1-8

Winer, Leah K; Cortez, Alex R; Kassam, Al; Quillin, Ralph C; Goodman, Michael D; Makley, Amy T; Sussman, Jeffrey J; Kuethe, Joshua W 2019. The Impact of a Comprehensive Resident Curriculum and Required Participation in "This Week in SCORE" on General Surgery ABSITE Performance and Well-Being. Journal of surgical education, ,

Baker, Jennifer E; Goodman, Michael D; Makley, Amy T; Stevens-Topie, Sabre M; Veile, Rosalie A; Mahoney, Eric J; Heyl, Judy R; Cox, Daniel B; Pritts, Timothy A; Athota, Krishna P 2018. Evaluation of a Novel Fibrin Sealant Patch in Hemorrhage Control After Vascular or Hepatic Injury. Military medicine, ,

Baker, Jennifer E; Martin, Grace E; Katsaros, Gianna; Lewis, Hannah V; Wakefield, Connor J; Josephs, Sean A; Nomellini, Vanessa; Makley, Amy T; Goodman, Michael D 2018. Variability of fluid administration during exploratory laparotomy for abdominal trauma. Trauma surgery & acute care open, 3 1, e000240

Jung, Andrew; Johnson, Mark; Veile, Rosalie; Friend, Lou Ann; Stevens-Topie, Sabre; Elterman, Joel; Pritts, Timothy; Makley, Amy; Goodman, Michael 2018. Variable saline resuscitation in a murine model of combined traumatic brain injury and haemorrhage. Brain injury, , 1-9

Martin, Grace E; Carroll, Christopher P; Plummer, Zachary J; Millar, D A; Pritts, Timothy A; Makley, Amy T; Joseph, Bellal A; Ngwenya, Laura B; Goodman, Michael D 2018. Safety and efficacy of brain injury guidelines at a Level III trauma center. The journal of trauma and acute care surgery, 84 3, 483-489

Martin, Grace E; He, Heng; Makley, Amy T; Pritts, Timothy A; Elterman, Joel B; Johannigman, Jay A; Goodman, Michael D 2018. Proximal penetrating extremity injuries-An opportunity to decrease overtriage? The journal of trauma and acute care surgery, 85 1, 122-127

Martin, Grace; Shah, Dhavan; Elson, Nora; Boudreau, Ryan; Hanseman, Dennis; Pritts, Timothy A; Makley, Amy T; Foreman, Brandon; Goodman, Michael D 2018. Relationship of Coagulopathy and Platelet Dysfunction to Transfusion Needs After Traumatic Brain Injury. Neurocritical care, 28 3, 330-337

Miano, Todd A; Cuker, Adam; Christie, Jason D; Martin, Niels; Smith, Brian; Makley, Amy T; Guo, Wensheng; Hennessy, Sean 2018. Comparative Effectiveness of Enoxaparin vs Dalteparin for Thromboprophylaxis After Traumatic Injury. Chest, 153 1, 133-142

Boudreau, Ryan M; Johnson, Mark; Veile, Rosalie; Friend, Lou Ann; Goetzman, Holly; Pritts, Timothy A; Caldwell, Charles C; Makley, Amy T; Goodman, Michael D 2017. Impact of tranexamic acid on coagulation and inflammation in murine models of traumatic brain injury and hemorrhage. The Journal of surgical research, 215 , 47-54

Martin, Grace E; Xia, Brent; Kim, Young; Johnson, Mark D; Veile, Rosalie; Friend, Lou Ann; Makley, Amy T; Caldwell, Charles C; Goodman, Michael D 2017. Platelet Function Changes in a Time-Dependent Manner Following Traumatic Brain Injury in a Murine Model. Shock (Augusta, Ga.), ,

Steuerwald, Michael Thomas; Robinson, Bryce R H; Hanseman, Dennis J; Makley, Amy; Pritts, Timothy A 2016. Prehospital airway technique does not influence incidence of ventilator-associated pneumonia in trauma patients. The journal of trauma and acute care surgery, 80 2, 283-8

Goodman, Michael D; Makley, Amy T; Hanseman, Dennis J; Pritts, Timothy A; Robinson, Bryce R H 2015. All the bang without the bucks: Defining essential point-of-care testing for traumatic coagulopathy. The journal of trauma and acute care surgery, 79 1, 117-24; discussion 1

Jernigan, Peter L; Makley, Amy T; Hoehn, Richard S; Edwards, Michael J; Pritts, Timothy A 2015. The role of sphingolipids in endothelial barrier function. Biological chemistry, 396 6-7, 681-91

Goodman, Michael D; Makley, Amy T; Campion, Eric M; Friend, Lou Ann W; Lentsch, Alex B; Pritts, Timothy A 2013. Preinjury alcohol exposure attenuates the neuroinflammatory response to traumatic brain injury. The Journal of surgical research, 184 2, 1053-8

Belizaire, Ritha M; Makley, Amy T; Campion, Eric M; Sonnier, Dennis I; Goodman, Michael D; Dorlac, Warren C; Friend, Lou Ann; Lentsch, Alex B; Pritts, Timothy A 2012. Resuscitation with washed aged packed red blood cell units decreases the proinflammatory response in mice after hemorrhage. The journal of trauma and acute care surgery, 73 2 Suppl 1, S128-33

Earnest, Ryan E; Sonnier, Dennis I; Makley, Amy T; Campion, Eric M; Wenke, Joseph C; Bailey, Stephanie R; Dorlac, Warren C; Lentsch, Alex B; Pritts, Timothy A 2012. Supplemental oxygen attenuates the increase in wound bacterial growth during simulated aeromedical evacuation in goats. The journal of trauma and acute care surgery, 73 1, 80-6

Makley, Amy T; Belizaire, Ritha; Campion, Eric M; Goodman, Michael D; Sonnier, Dennis I; Friend, Lou Ann; Schuster, Rebecca M; Bailey, Stephanie R; Johannigman, Jay A; Dorlac, Warren C; Lentsch, Alex B; Pritts, Timothy A 2012. Simulated aeromedical evacuation does not affect systemic inflammation or organ injury in a murine model of hemorrhagic shock. Military medicine, 177 8, 911-6

Makley, Amy T; Goodman, Michael D; Belizaire, Ritha M; Friend, Lou Ann W; Johannigman, Jay A; Dorlac, Warren C; Lentsch, Alex B; Pritts, Timothy A 2012. Damage control resuscitation decreases systemic inflammation after hemorrhage. The Journal of surgical research, 175 2, e75-82

Goodman, Michael D; Makley, Amy T; Huber, Nathan L; Clarke, Callisia N; Friend, Lou Ann W; Schuster, Rebecca M; Bailey, Stephanie R; Barnes, Stephen L; Dorlac, Warren C; Johannigman, Jay A; Lentsch, Alex B; Pritts, Timothy A 2011. Hypobaric hypoxia exacerbates the neuroinflammatory response to traumatic brain injury. The Journal of surgical research, 165 1, 30-7

Kasten, Kevin R; Makley, Amy T; Kagan, Richard J 2011. Update on the critical care management of severe burns. Journal of intensive care medicine, 26 4, 223-36

Sonnier, Dennis I; Makley, Amy T; Friend, Lou Ann W; Bailey, Stephanie R; Lentsch, Alex B; Pritts, Timothy A 2011. Hemorrhagic shock induces a proinflammatory milieu in the gut lumen. The Journal of surgical research, 170 2, 272-9

Goodman, Michael D; Makley, Amy T; Lentsch, Alex B; Barnes, Stephen L; Dorlac, Gina R; Dorlac, Warren C; Johannigman, Jay A; Pritts, Timothy A 2010. Traumatic brain injury and aeromedical evacuation: when is the brain fit to fly? The Journal of surgical research, 164 2, 286-93

Makley AT, Falcone RA 2010. Post-traumatic stress disorder in the pediatric patient Seminars in Pediatric Surgery, 19 4, 292

Makley AT, Goodman MD, Friend LA, Deters JS, Johannigman JA, Dorlac WC, Lentsch AB, Pritts TA 2010. Resuscitation with fresh whole blood ameliorates the inflammatory response after hemorrhagic shock Journal of Trauma, 68 2, 305

Makley AT, Goodman MD, Friend LA, Johannigman JA, Dorlac WC, Lentsch AB, Pritts TA 2010. Murine blood banking: characterization and comparisons to human blood Shock, 34 1, 40

Makley, Amy T; Falcone, Richard A 2010. Posttraumatic stress disorder in the pediatric trauma patient. Seminars in pediatric surgery, 19 4, 292-9

Makley, Amy T; Goodman, Michael D; Friend, Lou Ann W; Deters, Joseph S; Johannigman, Jay A; Dorlac, Warren C; Lentsch, Alex B; Pritts, Timothy A 2010. Resuscitation with fresh whole blood ameliorates the inflammatory response after hemorrhagic shock. The Journal of trauma, 68 2, 305-11

Makley, Amy T; Goodman, Michael D; Friend, Lou Ann W; Johannigman, Jay A; Dorlac, Warren C; Lentsch, Alex B; Pritts, Timothy A 2010. Murine blood banking: characterization and comparisons to human blood. Shock (Augusta, Ga.), 34 1, 40-5

Kasten K.;Makley A.;Kagan R. 12-01-2011. Burn and Inhalation Injuries Pediatric Critical Care, , 1489-1499

Dhar V.K.;Hanseman D.J.;Young G.;Browne D.;Makley A.T.;Sussman J.J.;Goodman M.D. 03-01-2020. Does Geographical Bias Impact the Match for General Surgery Residents? Journal of Surgical Education, 77 2, 260-266

Morris M.C.;Kim Y.;Blakeman T.C.;Stevens-Topie S.;Jung A.D.;Cox D.B.;Robinson B.B.R.;Pritts T.A.;Makley A.T.;Goodman M.D. 03-01-2020. Early Identification of Acute Lung Injury in a Porcine Model of Hemorrhagic Shock Journal of Surgical Research, 247 , 453-460

Morris M.;Singer K.;Niziolek G.;McGlone E.;Veile R.;Friend L.;Makley A.;Goodman M. 02-01-2020. Oxygenation extremes after traumatic brain injury transiently affect coagulation Thrombosis Research, 186 , 58-63

Cohen M.;Makley A.;Cushieri J.;Schreiber M.;Spinella P. 02-01-2010. Discussion Journal of Trauma - Injury, Infection and Critical Care, 68 2, 310-311

Baker J.E.;Martin G.E.;Katsaros G.;Lewis H.V.;Wakefield C.J.;Josephs S.A.;Nomellini V.;Makley A.T.;Goodman M.D. 01-01-2018. Variability of fluid administration during exploratory laparotomy for abdominal trauma Trauma Surgery and Acute Care Open, 3 1,

Abstract Publications

Campion EM, Goodman MD, Makley AT, Huber NL, Clarke CN, Friend LW, Schuster RM, Bailey SR, Lentsch AB, Dorlac WC, Johannigman JA, Pritts TA 2010. Hypobaric hypoxia exacerbates the inflammatory response after blunt traumatic brain injury in mice J Surg Res, 158 , 214


Makley AT, Goodman MD, Friend LA, Bailey SR, Lentsch AB, Pritts TA 2010. Damage control resuscitation with aged blood products exacerbates the systemic inflammatory response following hemorrhagic shock J Surg Res, 158 , 423


Makley AT, Goodman MD, Friend LA, Johannigman JA, Dorlac WC, Lentsch AB, Pritts TA 2010. Damage control resuscitation with a 1:1 ratio of plasma and packed red blood cells decreases systemic inflammation following hemorrhagic shock in mice Inflammation Research, 59 S1, S28


Goodman MD. Makley AT, Lentsch AB, Pritts TA 2009. Acute alcohol intoxication attenuates the neuroinflammatory response to traumatic brain injury J Am College Surgeons, 209 3S, S45


Makley AT, Friend LAW, Goodman MD, Blanchard JN, Lentsch AB, Pritts TA 04-2009. Resuscitation strategy alters response to hemorrhage Experimental Biology, ,