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Daniel Nelson, MD

Professor - Clin Aff

Associate Professor of Clinical Psychiatry and Medical Director of the Children's Psychiatry Unit at Cincinnati Children's Hospital Medical Center

COM Psychiatry Affiliate Programs-CCHMC

  • Medical Degree: University of Oklahoma Health Sciences Center
  • Residency: Medical Center Hospital/Audie Murphy
  • Fellowship: San Antonio Children's Center, Southwest Neuropsychiatric Institute
Research Interests

Dr. Nelson is certified in General Psychiatry and Child and Adolescent Psychiatry.

Contact Information
  • Stetson Building
  • Suite 3200
  • 260 Stetson Street
  • Cincinnati, Ohio 45219
  • Office 513-558-7700
  • Email

Peer Reviewed Publications

Chauhan, Vinita S; Furr, Samantha R; Sterka, David G; Nelson, Daniel A; Moerdyk-Schauwecker, Megan; Marriott, Ian; Grdzelishvili, Valery Z 2010. Vesicular stomatitis virus infects resident cells of the central nervous system and induces replication-dependent inflammatory responses. Virology, 400 2, 187-96

Davis, Ashley; Martinez, Sarah; Nelson, Daniel; Middleton, Kim 2010. A tubulin polymerization microassay used to compare ligand efficacy. Methods in cell biology, 95 , 331-51

Howard, Daniel L; Boyd, Carlton L; Nelson, Daniel K; Godley, Paul 2010. Getting from A to IRB: developing an institutional review board at a historically black university. Journal of empirical research on human research ethics : JERHRE, 5 1, 75-81

Nelson, Daniel A; Tolbert, Melanie D; Clemens, Mark G; Bost, Kenneth L 2010. Interleukin-27 expression following infection with the murine gammaherpesvirus 68. Cytokine, 51 2, 184-94

Nelson, J Daniel 2010. J. Daniel Nelson, MD. The ocular surface, 8 2, 96-8

Saybolt, Matthew D; Alter, Scott M; Dos Santos, Frank; Calello, Diane P; Rynn, Kevin O; Nelson, Daniel A; Merlin, Mark A 2010. Naloxone in cardiac arrest with suspected opioid overdoses. Resuscitation, 81 1, 42-6

Crow, Jean M; Nelson, J Daniel; Remington, Susann G 2009. Human lipocalin-1 association with 3H-testosterone and 3H-estradiol. Current eye research, 34 12, 1042-9

Hoopes, J Todd; Stark, Caren J; Kim, Han Ah; Sussman, Daniel J; Donovan, David M; Nelson, Daniel C 2009. Use of a bacteriophage lysin, PlyC, as an enzyme disinfectant against Streptococcus equi. Applied and environmental microbiology, 75 5, 1388-94

Liu, Haixia; Begley, Carolyn; Chen, Minhua; Bradley, Arthur; Bonanno, Joseph; McNamara, Nancy A; Nelson, J Daniel; Simpson, Trefford 2009. A link between tear instability and hyperosmolarity in dry eye. Investigative ophthalmology & visual science, 50 8, 3671-9

Nelson, Daniel A; Bradley, Joanna K; Arya, Rajiv; Ianosi-Irimie, Monica; Marques-Baptista, Andreia; Merlin, Mark A 2009. Babesiosis as a rare cause of fever in the immunocompromised patient: a case report. Cases journal, 2 , 7420

Remington, Susann G; Crow, Jean M; Nelson, J Daniel 2009. Antibodies to endogenous tear protein in normal human tears. Current eye research, 34 10, 819-23

Schuch, Raymond; Fischetti, Vincent A; Nelson, Daniel C 2009. A genetic screen to identify bacteriophage lysins. Methods in molecular biology (Clifton, N.J.), 502 , 307-19

Celia, Laura K; Nelson, Daniel; Kerr, David E 2008. Characterization of a bacteriophage lysin (Ply700) from Streptococcus uberis. Veterinary microbiology, 130 1-2, 107-17

Johnson, Blair T; Shaw, Lindsey N; Nelson, Daniel C; Mayo, John A 2008. Extracellular proteolytic activities expressed by Bacillus pumilus isolated from endodontic and periodontal lesions. Journal of medical microbiology, 57 Pt 5, 643-51

K├Âller, Thomas; Nelson, Daniel; Nakata, Masanobu; Kreutzer, Michael; Fischetti, Vincent A; Glocker, Michael O; Podbielski, Andreas; Kreikemeyer, Bernd 2008. PlyC, a novel bacteriophage lysin for compartment-dependent proteomics of group A streptococci. Proteomics, 8 1, 140-8

Nelson, Daniel A; Nirmaier, Jamie L; Singh, Sam J; Tolbert, Melanie D; Bost, Kenneth L 2008. Ecstasy (3,4-methylenedioxymethamphetamine) limits murine gammaherpesvirus-68 induced monokine expression. Brain, behavior, and immunity, 22 6, 912-22

Remington, Susann G; Crow, Jean M; Nelson, J Daniel 2008. Secretoglobins: lacrimal gland-specific rabbit lipophilin mRNAs. Investigative ophthalmology & visual science, 49 7, 2856-62

Henderson, Gail E; Churchill, Larry R; Davis, Arlene M; Easter, Michele M; Grady, Christine; Joffe, Steven; Kass, Nancy; King, Nancy M P; Lidz, Charles W; Miller, Franklin G; Nelson, Daniel K; Peppercorn, Jeffrey; Rothschild, Barbra Bluestone; Sankar, Pamela; Wilfond, Benjamin S; Zimmer, Catherine R 2007. Clinical trials and medical care: defining the therapeutic misconception. PLoS medicine, 4 11, e324

Henderson, Gail E; Corneli, Amy L; Mahoney, David B; Nelson, Daniel K; Mwansambo, Charles 2007. Applying research ethics guidelines: the view from a sub-saharan research ethics committee. Journal of empirical research on human research ethics : JERHRE, 2 2, 41-8

Nelson, Daniel A; Tolbert, Melanie D; Singh, Sam J; Bost, Kenneth L 2007. Expression of neuronal trace amine-associated receptor (Taar) mRNAs in leukocytes. Journal of neuroimmunology, 192 1-2, 21-30

Porter, Corrine J; Schuch, Raymond; Pelzek, Adam J; Buckle, Ashley M; McGowan, Sheena; Wilce, Matthew C J; Rossjohn, Jamie; Russell, Ryann; Nelson, Daniel; Fischetti, Vincent A; Whisstock, James C 2007. The 1.6 A crystal structure of the catalytic domain of PlyB, a bacteriophage lysin active against Bacillus anthracis. Journal of molecular biology, 366 2, 540-50

Schaumberg, Debra A; Gulati, Abha; Mathers, William D; Clinch, Thomas; Lemp, Michael A; Nelson, J Daniel; Foulks, Gary N; Dana, Reza 2007. Development and validation of a short global dry eye symptom index. The ocular surface, 5 1, 50-7

Fischetti, Vincent A; Nelson, Daniel; Schuch, Raymond 2006. Reinventing phage therapy: are the parts greater than the sum? Nature biotechnology, 24 12, 1508-11

Henderson, Gail E; Easter, Michele M; Zimmer, Catherine; King, Nancy M P; Davis, Arlene M; Rothschild, Barbra Bluestone; Churchill, Larry R; Wilfond, Benjamin S; Nelson, Daniel K 2006. Therapeutic misconception in early phase gene transfer trials. Social science & medicine (1982), 62 1, 239-53

Hong, Zhigang; Hong, Fangxiao; Olschewski, Andrea; Cabrera, Jesus A; Varghese, Anthony; Nelson, Daniel P; Weir, E Kenneth 2006. Role of store-operated calcium channels and calcium sensitization in normoxic contraction of the ductus arteriosus. Circulation, 114 13, 1372-9

Nelson, Daniel; Schuch, Raymond; Chahales, Peter; Zhu, Shiwei; Fischetti, Vincent A 2006. PlyC: a multimeric bacteriophage lysin. Proceedings of the National Academy of Sciences of the United States of America, 103 28, 10765-70

Sabharwal, Hemant; Michon, Francis; Nelson, Daniel; Dong, Wenling; Fuchs, Kathleen; Manjarrez, Roberto Carreno; Sarkar, Arun; Uitz, Catherine; Viteri-Jackson, Ann; Suarez, Romeo S Rodriguez; Blake, Milan; Zabriskie, John B 2006. Group A streptococcus (GAS) carbohydrate as an immunogen for protection against GAS infection. The Journal of infectious diseases, 193 1, 129-35

Yoong, Pauline; Schuch, Raymond; Nelson, Daniel; Fischetti, Vincent A 2006. PlyPH, a bacteriolytic enzyme with a broad pH range of activity and lytic action against Bacillus anthracis. Journal of bacteriology, 188 7, 2711-4

Ampel, Neil M; Nelson, Daniel K; Chavez, Suzette; Naus, Kathryn A; Herman, Amanda B; Li, Lijin; Simmons, Keira A; Pappagianis, Demosthenes 2005. Preliminary evaluation of whole-blood gamma interferon release for clinical assessment of cellular immunity in patients with active coccidioidomycosis. Clinical and diagnostic laboratory immunology, 12 6, 700-4

Ampel, Neil M; Nelson, Daniel K; Li, Lijin; Dionne, Sara O; Lake, Douglas F; Simmons, Keira A; Pappagianis, Demosthenes 2005. The mannose receptor mediates the cellular immune response in human coccidioidomycosis. Infection and immunity, 73 4, 2554-5

Barzman, Drew H; McConville, Brian J; Masterson, Brian; McElroy, Susan; Sethuraman, Gopalan; Moore, Krissell; Kahwaty, Ann-Marie; Nelson, Daniel 2005. Impulsive aggression with irritability and responsive to divalproex: a pediatric bipolar spectrum disorder phenotype? Journal of affective disorders, 88 3, 279-85

Cheng, Qi; Nelson, Daniel; Zhu, Shiwei; Fischetti, Vincent A 2005. Removal of group B streptococci colonizing the vagina and oropharynx of mice with a bacteriophage lytic enzyme. Antimicrobial agents and chemotherapy, 49 1, 111-7

Hong, Zhigang; Smith, Andrew J; Archer, Stephen L; Wu, Xi-Chen; Nelson, Daniel P; Peterson, Douglas; Johnson, Gerhard; Weir, E Kenneth 2005. Pergolide is an inhibitor of voltage-gated potassium channels, including Kv1.5, and causes pulmonary vasoconstriction. Circulation, 112 10, 1494-9

Le, Quynh-Thu; Shi, Gongyi; Cao, Hongbin; Nelson, Daniel W; Wang, Yingyun; Chen, Eunice Y; Zhao, Shuchun; Kong, Christina; Richardson, Donna; O'Byrne, Ken J; Giaccia, Amato J; Koong, Albert C 2005. Galectin-1: a link between tumor hypoxia and tumor immune privilege. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 23 35, 8932-41

Lynn, Mary R; Nelson, Daniel K 2005. Common (mis)perceptions about IRB review of human subjects research. Nursing science quarterly, 18 3, 264-70

Mertzanis, Polyxane; Abetz, Linda; Rajagopalan, Krithika; Espindle, Derek; Chalmers, Robin; Snyder, Christopher; Caffery, Barbara; Edrington, Timothy; Simpson, Trefford; Nelson, J Daniel; Begley, Carolyn 2005. The relative burden of dry eye in patients' lives: comparisons to a U.S. normative sample. Investigative ophthalmology & visual science, 46 1, 46-50

Nelson, Daniel A; Bost, Kenneth L 2005. Quantification of hemokinin-1 peptide production and secretion from mouse B cells. Cellular immunology, 237 2, 115-22

Nelson, Daniel W; Cao, Hongbin; Zhu, Yonghua; Sunar-Reeder, Bulbin; Choi, Clara Y H; Faix, James D; Brown, J Martin; Koong, Albert C; Giaccia, Amato J; Le, Quynh-Thu 2005. A noninvasive approach for assessing tumor hypoxia in xenografts: developing a urinary marker for hypoxia. Cancer research, 65 14, 6151-8

Remington, Susann G; Nelson, J Daniel 2005. Secretoglobins: sexually dimorphic expression of androgen-binding protein mRNA in mouse lacrimal glands. Investigative ophthalmology & visual science, 46 1, 31-8

Henderson, Gail E; Davis, Arlene M; King, Nancy M P; Easter, Michele M; Zimmer, Catherine R; Rothschild, Barbra Bluestone; Wilfond, Benjamin S; Nelson, Daniel K; Churchill, Larry R 2004. Uncertain benefit: investigators' views and communications in early phase gene transfer trials. Molecular therapy : the journal of the American Society of Gene Therapy, 10 2, 225-31

Hong, Zhigang; Olschewski, Andrea; Reeve, Helen L; Nelson, Daniel P; Hong, Fangxiao; Weir, E Kenneth 2004. Nordexfenfluramine causes more severe pulmonary vasoconstriction than dexfenfluramine. American journal of physiology. Lung cellular and molecular physiology, 286 3, L531-8

Hong, Zhigang; Weir, E Kenneth; Nelson, Daniel P; Olschewski, Andrea 2004. Subacute hypoxia decreases voltage-activated potassium channel expression and function in pulmonary artery myocytes. American journal of respiratory cell and molecular biology, 31 3, 337-43

Nelson, Daniel 2004. Phage taxonomy: we agree to disagree. Journal of bacteriology, 186 21, 7029-31

Nelson, Daniel A; Bost, Kenneth L 2004. Non-neuronal mammalian tachykinin expression. Frontiers in bioscience : a journal and virtual library, 9 , 2166-76

Nelson, Daniel A; Marriott, Ian; Bost, Kenneth L 2004. Expression of hemokinin 1 mRNA by murine dendritic cells. Journal of neuroimmunology, 155 1-2, 94-102

Olschewski, Andrea; Hong, Zhigang; Peterson, Douglas A; Nelson, Daniel P; Porter, Valerie A; Weir, E Kenneth 2004. Opposite effects of redox status on membrane potential, cytosolic calcium, and tone in pulmonary arteries and ductus arteriosus. American journal of physiology. Lung cellular and molecular physiology, 286 1, L15-22

Rezaie-Majd, Shahrzad; Murar, Jozef; Nelson, Daniel P; Kelly, Rosemary F; Hong, Zhigang; Lang, Irene M; Varghese, Anthony; Weir, E Kenneth 2004. Increased release of serotonin from rat ileum due to dexfenfluramine. American journal of physiology. Regulatory, integrative and comparative physiology, 287 5, R1209-13

Romero-Ramirez, Lorenzo; Cao, Hongbin; Nelson, Daniel; Hammond, Ester; Lee, Ann-Hwee; Yoshida, Hiderou; Mori, Kazutoshi; Glimcher, Laurie H; Denko, Nicholas C; Giaccia, Amato J; Le, Quynh-Thu; Koong, Albert C 2004. XBP1 is essential for survival under hypoxic conditions and is required for tumor growth. Cancer research, 64 17, 5943-7

Yoong, Pauline; Schuch, Raymond; Nelson, Daniel; Fischetti, Vincent A 2004. Identification of a broadly active phage lytic enzyme with lethal activity against antibiotic-resistant Enterococcus faecalis and Enterococcus faecium. Journal of bacteriology, 186 14, 4808-12

Begley, Carolyn G; Chalmers, Robin L; Abetz, Linda; Venkataraman, Kitty; Mertzanis, Polyxane; Caffery, Barbara A; Snyder, Christopher; Edrington, Timothy; Nelson, Daniel; Simpson, Trefford 2003. The relationship between habitual patient-reported symptoms and clinical signs among patients with dry eye of varying severity. Investigative ophthalmology & visual science, 44 11, 4753-61

Califf, Robert M; Morse, Michael A; Wittes, Janet; Goodman, Steven N; Nelson, Daniel K; DeMets, David L; Iafrate, R Peter; Sugarman, Jeremy 2003. Toward protecting the safety of participants in clinical trials. Controlled clinical trials, 24 3, 256-71

Kelly, Rosemary F; Murar, Jozef; Hong, Zhigang; Nelson, Daniel P; Hong, Fangxiao; Varghese, Anthony; Weir, E Kenneth 2003. Low potassium dextran lung preservation solution reduces reactive oxygen species production. The Annals of thoracic surgery, 75 6, 1705-10

Nelson, Daniel R; Fleming, George T; Kilcup, Gregory W 2003. Up quark mass in lattice QCD with three light dynamical quarks and implications for strong CP invariance. Physical review letters, 90 2, 021601

Nelson, Daniel; Schuch, Raymond; Zhu, Shiwei; Tscherne, Donna M; Fischetti, Vincent A 2003. Genomic sequence of C1, the first streptococcal phage. Journal of bacteriology, 185 11, 3325-32

Wagner, Todd H; Bhandari, Aman; Chadwick, Gary L; Nelson, Daniel K 2003. The cost of operating institutional review boards (IRBs). Academic medicine : journal of the Association of American Medical Colleges, 78 6, 638-44

Nelson, Daniel 2002. Violence against elderly people: a neglected problem. Lancet, 360 9339, 1094

Nelson, J Daniel 2002. Diagnosis and treatment of the dry eye: a clinical perspective. Advances in experimental medicine and biology, 506 Pt B, 1067-78

Olschewski, Andrea; Hong, Zhigang; Nelson, Daniel P; Weir, E Kenneth 2002. Graded response of K+ current, membrane potential, and [Ca2+]i to hypoxia in pulmonary arterial smooth muscle. American journal of physiology. Lung cellular and molecular physiology, 283 5, L1143-50

Remington, Susann G; Nelson, J Daniel 2002. mRNA encoding a new lipolytic enzyme expressed in rabbit lacrimal glands. Investigative ophthalmology & visual science, 43 12, 3617-24

Remington, Susann G; Nelson, J Daniel 2002. Lipase mRNAs expressed in lacrimal and harderian glands. Advances in experimental medicine and biology, 506 Pt A, 115-9

Schuch, Raymond; Nelson, Daniel; Fischetti, Vincent A 2002. A bacteriolytic agent that detects and kills Bacillus anthracis. Nature, 418 6900, 884-9

Churchill, Larry R; Nelson, Daniel K; Henderson, Gail E; King, Nancy M P; Davis, Arlene M; Leahey, Erin; Wilfond, Benjamin S . Assessing benefits in clinical research: why diversity in benefit assessment can be risky. IRB, 25 3, 1-8

King, Nancy M P; Henderson, Gail E; Churchill, Larry R; Davis, Arlene M; Hull, Sara Chandros; Nelson, Daniel K; Parham-Vetter, P Christy; Rothschild, Barbara Bluestone; Easter, Michele M; Wilfond, Benjamin S . Consent forms and the therapeutic misconception: the example of gene transfer research. IRB, 27 1, 1-8

Rajagopalan, Krithika; Abetz, Linda; Mertzanis, Polyxane; Espindle, Derek; Begley, Carolyn; Chalmers, Robin; Caffery, Barbara; Snyder, Christopher; Nelson, J Daniel; Simpson, Trefford; Edrington, Timothy . Comparing the discriminative validity of two generic and one disease-specific health-related quality of life measures in a sample of patients with dry eye. Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research, 8 2, 168-74