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Photo of  Eric S. Wohleb, PhD

Eric S. Wohleb, PhD

Associate Professor

Pharmacology & Systems Physiology | College of Medicine

  • Associate Research Scientist: Yale University
  • Postdoctoral Research Associate: Yale University
  • Doctoral Degree: The Ohio State University (Neuroscience; Neuroimmunology)
  • Bachelor's Degree: Saint John's University (Mathematics; Psychology)
Contact Information

Peer Reviewed Publications

Bollinger, Justin L; Horchar, Matthew J; Wohleb, Eric S 2020. Diazepam limits microglia-mediated neuronal remodeling in the prefrontal cortex and associated behavioral consequences following chronic unpredictable stress. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, ,

Gerhard, Danielle M; Pothula, Santosh; Liu, Rong-Jian; Wu, Min; Li, Xiao-Yuan; Girgenti, Matthew J; Taylor, Seth R; Duman, Catharine H; Delpire, Eric; Picciotto, Marina; Wohleb, Eric S; Duman, Ronald S 2020. GABA interneurons are the cellular trigger for ketamine's rapid antidepressant actions. The Journal of clinical investigation, 130 3, 1336-1349

Bollinger, J L; Wohleb, E S 2019. The formative role of microglia in stress-induced synaptic deficits and associated behavioral consequences. Neuroscience letters, 711 , 134369

Deyama, Satoshi; Bang, Eunyoung; Wohleb, Eric S; Li, Xiao-Yuan; Kato, Taro; Gerhard, Danielle M; Dutheil, Sophie; Dwyer, Jason M; Taylor, Seth R; Picciotto, Marina R; Duman, Ronald S 2019. Role of Neuronal VEGF Signaling in the Prefrontal Cortex in the Rapid Antidepressant Effects of Ketamine. The American journal of psychiatry, 176 5, 388-400

Girgenti, Matthew J; Wohleb, Eric S; Mehta, Sameet; Ghosal, Sriparna; Fogaca, Manoela V; Duman, Ronald S 2019. Prefrontal cortex interneurons display dynamic sex-specific stress-induced transcriptomes. Translational psychiatry, 9 1, 292

Horchar, Matthew J; Wohleb, Eric S 2019. Glucocorticoid receptor antagonism prevents microglia-mediated neuronal remodeling and behavioral despair following chronic unpredictable stress Brain, Behavior, and Immunity, ,

Franklin, Tina C; Wohleb, Eric S; Zhang, Yi; Foga├ža, Manoela; Hare, Brendan; Duman, Ronald S 2018. Persistent Increase in Microglial RAGE Contributes to Chronic Stress-Induced Priming of Depressive-like Behavior. Biological psychiatry, 83 1, 50-60

Wohleb, Eric S; Terwilliger, Rosemarie; Duman, Catharine H; Duman, Ronald S 2018. Stress-Induced Neuronal Colony Stimulating Factor 1 Provokes Microglia-Mediated Neuronal Remodeling and Depressive-like Behavior Biological Psychiatry, 83 1, 38-49

Bath, Kevin G; Russo, Scott J; Pleil, Kristen E; Wohleb, Eric S; Duman, Ronald S; Radley, Jason J 2017. Circuit and synaptic mechanisms of repeated stress: Perspectives from differing contexts, duration, and development. Neurobiology of stress, 7 , 137-151

Wohleb, Eric S; Delpech, Jean-Christophe 2017. Dynamic cross-talk between microglia and peripheral monocytes underlies stress-induced neuroinflammation and behavioral consequences. Progress in neuro-psychopharmacology & biological psychiatry, 79 Pt A, 40-48

Wohleb, Eric S; Gerhard, Danielle; Thomas, Alex; Duman, Ronald S 2017. Molecular and Cellular Mechanisms of Rapid-Acting Antidepressants Ketamine and Scopolamine. Current neuropharmacology, 15 1, 11-20

Wohleb, Eric S 2016. Neuron-Microglia Interactions in Mental Health Disorders: "For Better, and For Worse" Frontiers in Immunology, 7 , 544

Wohleb, Eric S; Franklin, Tina; Iwata, Masaaki; Duman, Ronald S 2016. Integrating neuroimmune systems in the neurobiology of depression Nature Reviews Neuroscience, 17 8, 497-511

Wohleb, Eric S; Wu, Min; Gerhard, Danielle M; Taylor, Seth R; Picciotto, Marina R; Alreja, Meenakshi; Duman, Ronald S 2016. GABA interneurons mediate the rapid antidepressant-like effects of scopolamine The Journal of Clinical Investigation, 126 7, 2482-94