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Photo of  Manuel S. Vilareal, MD

Manuel S. Vilareal, MD

Associate Professor of Clinical-Affiliate

Internal Medicine | College of Medicine

Education/Credentials
  • Bachelor's Degree: University of the Philippines
  • Medical Degree: De La Salle University-Emilio Aguinaldo College of Medicine
  • Residency: UMDNJ-Robert Wood Johnson Medical School
  • Fellowship: West-Los Angeles VA Medical Center-UCLA School of Medicine
Board Certifications & Licenses

American Board of Allergy and Immunology (Certification Date: 19951009) - (Recertification Date: 20151231)

Specialties

Allergy and Immunology
Geriatric Medicine
Internal Medicine

Contact Information

Clinical Interests

Allergy and Immunology

Geriatric Medicine

Peer Reviewed Publications

Kannan, Jennifer A; Brokamp, Cole; Bernstein, David I; LeMasters, Grace K; Hershey, Gurjit K Khurana; Villareal, Manuel S; Lockey, James E; Ryan, Patrick H 2017. Parental Snoring and Environmental Pollutants, but Not Aeroallergen Sensitization, Are Associated with Childhood Snoring in a Birth Cohort. Pediatric allergy, immunology, and pulmonology, 30 1, 31-38

Kannan, Jennifer A; Bernstein, David I; Bernstein, Cheryl K; Ryan, Patrick H; Bernstein, Jonathan A; Villareal, Manuel S; Smith, Andrew M; Lenz, Peter H; Epstein, Tolly G 2015. Significant predictors of poor quality of life in older asthmatics. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 115 3, 198-204

Epstein, Tolly G; Kesavalu, Banurekha; Bernstein, Cheryl K; Ryan, Patrick H; Bernstein, Jonathan A; Zimmermann, Nives; Lummus, Zana; Villareal, Manuel S; Smith, Andrew M; Lenz, Peter H; Bernstein, David I 2013. Chronic traffic pollution exposure is associated with eosinophilic, but not neutrophilic inflammation in older adult asthmatics. The Journal of asthma : official journal of the Association for the Care of Asthma, 50 9, 983-9

Epstein, Tolly G; LeMasters, Grace K; Bernstein, David I; Ericksen, Mark B; Martin, Lisa J; Ryan, Patrick H; Biagini Myers, Jocelyn M; Butsch Kovacic, Melinda S; Lindsey, Mark A; He, Hua; Reponen, Tiina; Villareal, Manuel S; Lockey, James E; Bernstein, Cheryl K; Khurana Hershey, Gurjit K 2012. Genetic variation in small proline rich protein 2B as a predictor for asthma among children with eczema. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 108 3, 145-50

Epstein, Tolly G; Ryan, Patrick H; LeMasters, Grace K; Bernstein, Cheryl K; Levin, Linda S; Bernstein, Jonathan A; Villareal, Manuel S; Bernstein, David I 2012. Poor asthma control and exposure to traffic pollutants and obesity in older adults. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 108 6, 423-428.e2

Biagini Myers, Jocelyn M; Wang, Ning; LeMasters, Grace K; Bernstein, David I; Epstein, Tolly G; Lindsey, Mark A; Ericksen, Mark B; Chakraborty, Ranajit; Ryan, Patrick H; Villareal, Manuel S; Burkle, Jeff W; Lockey, James E; Reponen, Tiina; Khurana Hershey, Gurjit K 2010. Genetic and environmental risk factors for childhood eczema development and allergic sensitization in the CCAAPS cohort. The Journal of investigative dermatology, 130 2, 430-7

Villareal, M S; Klaustermeyer, W B; Hahn, T J; Gordon, E H 1996. Osteoporosis in steroid-dependent asthma. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 76 4, 369-72

Reponen T.;Singh U.;Vesper S.;Johansson E.;Adhikari A.;Ryan P.;Levin L.;Zheng S.;Burkle J.;Grinshpun S.A.;Bernstein D.I.;Lockey J.;Villareal M.;Hershey G.K.K.;LeMasters G. 12-01-2011. Effect of microbial exposure on the development of Asthma in children 12th International Conference on Indoor Air Quality and Climate 2011, 1 , 552-553

Ryan P.;Bernstein D.;Lockey J.;Reponen T.;Levin L.;Grinshpun S.;Villareal M.;Khurana Hershey G.;Burkle J.;LeMasters G. 12-01-2009. Exposure to traffic-related particles and endotoxin during infancy is associated with wheezing at ag American Journal of Respiratory and Critical Care Medicine, 180 11, 1068-1075

Campo P.;Kalra H.;Levin L.;Reponen T.;Olds R.;Lummus Z.;Cho S.;Khurana Hershey G.;Lockey J.;Villareal M.;Stanforth S.;LeMasters G.;Bernstein D. 12-01-2006. Influence of dog ownership and high endotoxin on wheezing and atopy during infancy Journal of Allergy and Clinical Immunology, 118 6, 1271-1278

LeMasters G.;Wilson K.;Levin L.;Biagini J.;Ryan P.;Lockey J.;Stanforth S.;Maier S.;Yang J.;Burkle J.;Villareal M.;Khurana Hershey G.;Bernstein D. 10-01-2006. High prevalence of aeroallergen sensitization among infants of atopic parents Journal of Pediatrics, 149 4, 505-511

Johansson E.;Reponen T.;Vesper S.;Levin L.;Lockey J.;Ryan P.;Bernstein D.;Villareal M.;Khurana Hershey G.;Schaffer C.;LeMasters G. 09-01-2013. Microbial content of household dust associated with exhaled NO in asthmatic children Environment International, 59 , 141-147

Brunst K.;Ryan P.;Lockey J.;Bernstein D.;Mckay R.;Khurana Hershey G.;Villareal M.;Biagini Myers J.;Levin L.;Burkle J.;Evans S.;Lemasters G. 08-01-2012. Unraveling the relationship between aeroallergen sensitization, gender, second-hand smoke exposure, Pediatric Allergy and Immunology, 23 5, 479-487

Reponen T.;Vesper S.;Levin L.;Johansson E.;Ryan P.;Burkle J.;Grinshpun S.;Zheng S.;Bernstein D.;Lockey J.;Villareal M.;Khurana Hershey G.;Lemasters G. 08-01-2011. High environmental relative moldiness index during infancy as a predictor of asthma at 7 years of ag Annals of Allergy, Asthma and Immunology, 107 2, 120-126

Ryan P.;LeMasters G.;Biagini J.;Bernstein D.;Grinshpun S.;Shukla R.;Wilson K.;Villareal M.;Burkle J.;Lockey J. 08-01-2005. Is it traffic type, volume, or distance? Wheezing in infants living near truck and bus traffic Journal of Allergy and Clinical Immunology, 116 2, 279-284

Newman N.;Ryan P.;Le Masters G.;Levin L.;Bernstein D.;Hershey G.;Lockey J.;Villareal M.;Reponen T.;Grinshpun S.;Sucharew H.;Dietrich K. 06-01-2013. Traffic-related air pollution exposure in the first year of life and behavioral scores at 7 years of Environmental Health Perspectives, 121 6, 731-736

Biagini Myers J.;Khurana Hershey G.;Deka R.;Burkle J.;Levin L.;Bernstein D.;Villareal M.;Lockey J.;Reponen T.;Gareri J.;Lubetsky A.;Koren G.;Lemasters G. 06-01-2012. Asking the right questions to ascertain early childhood secondhand smoke exposures Journal of Pediatrics, 160 6, 1050-1051

Biagini J.;LeMasters G.;Ryan P.;Levin L.;Reponen T.;Bernstein D.;Villareal M.;Khurana Hershey G.;Burkle J.;Lockey J. 06-01-2006. Environmental risk factors of rhinitis in early infancy Pediatric Allergy and Immunology, 17 4, 278-284

Smith A.M.;Villareal M.;Bernstein D.I.;Swikert D.J. 05-01-2012. Asthma in the elderly: Risk factors and impact on physical function Annals of Allergy, Asthma and Immunology, 108 5, 305-310

Iossifova Y.;Reponen T.;Bernstein D.;Levin L.;Kalra H.;Campo P.;Villareal M.;Lockey J.;Hershey G.;LeMasters G. 05-01-2007. House dust (1-3)-?-D-glucan and wheezing in infants Allergy: European Journal of Allergy and Clinical Immunology, 62 5, 504-513

Kim H.;Levin L.;Lemasters G.;Villareal M.;Evans S.;Lockey J.;Khurana Hershey G.;Bernstein D. 04-01-2012. Validating childhood symptoms with physician-diagnosed allergic rhinitis Annals of Allergy, Asthma and Immunology, 108 4, 228-231

Kannan J.;Brokamp C.;Bernstein D.;Lemasters G.;Hershey G.;Villareal M.;Lockey J.;Ryan P. 03-01-2017. Parental Snoring and Environmental Pollutants, but Not Aeroallergen Sensitization, Are Associated wi Pediatric, Allergy, Immunology, and Pulmonology, 30 1, 31-38

Sucharew H.;Ryan P.;Bernstein D.;Succop P.;Khurana Hershey G.;Lockey J.;Villareal M.;Reponen T.;Grinshpun S.;Lemasters G. 03-01-2010. Exposure to traffic exhaust and night cough during early childhood: The CCAAPS birth cohort Pediatric Allergy and Immunology, 21 2 PART 1, 253-259

Codispoti C.;Lemasters G.;Levin L.;Reponen T.;Ryan P.;Biagini Myers J.;Villareal M.;Burkle J.;Evans S.;Lockey J.;Khurana Hershey G.;Bernstein D. 02-01-2015. Traffic pollution is associated with early childhood aeroallergen sensitization Annals of Allergy, Asthma and Immunology, 114 2, 126-133.e3

Ryan P.;LeMasters G.;Biswas P.;Levin L.;Hu S.;Lindsey M.;Bernstein D.;Lockey J.;Villareal M.;Khurana Hershey G.;Grinshpun S. 02-01-2007. A comparison of proximity and land use regression traffic exposure models and wheezing in infants Environmental Health Perspectives, 115 2, 278-284

Codispoti C.;Bernstein D.;Levin L.;Reponen T.;Ryan P.;Biagini Myers J.;Villareal M.;Burkle J.;Lummus Z.;Lockey J.;Khurana Hershey G.;Lemasters G. 01-01-2015. Early-life mold and tree sensitivity is associated with allergic eosinophilic rhinitis at 4 years of Annals of Allergy, Asthma and Immunology, 114 3, 193-198.e4

Amin P.;Levin L.;Epstein T.;Ryan P.;LeMasters G.;Khurana Hershey G.;Reponen T.;Villareal M.;Lockey J.;Bernstein D. 01-01-2014. Optimum Predictors of Childhood Asthma: Persistent Wheeze or the Asthma Predictive Index? Journal of Allergy and Clinical Immunology: In Practice, 2 6, 709-715.e2

Cheng G.;Smith A.;Levin L.;Epstein T.;Ryan P.;Lemasters G.;Khurana Hershey G.;Reponen T.;Villareal M.;Lockey J.;Bernstein D. 01-01-2014. Duration of day care attendance during infancy predicts asthma at the age of seven: The Cincinnati C Clinical and Experimental Allergy, 44 10, 1274-1281

Epstein T.;Lemasters G.;Bernstein D.;Ericksen M.;Martin L.;Ryan P.;Biagini Myers J.;Butsch Kovacic M.;Lindsey M.;He H.;Reponen T.;Villareal M.;Lockey J.;Bernstein C.;Khurana Hershey G. 01-01-2012. Genetic variation in small proline rich protein 2B as a predictor for asthma among children with ecz Annals of Allergy, Asthma and Immunology, 108 3,

Epstein T.;Ryan P.;Lemasters G.;Bernstein C.;Levin L.;Bernstein J.;Villareal M.;Bernstein D. 01-01-2012. Poor asthma control and exposure to traffic pollutants and obesity in older adults Annals of Allergy, Asthma and Immunology, 108 6,

Reponen T.;Lockey J.;Bernstein D.;Vesper S.;Levin L.;Khurana Hershey G.;Zheng S.;Ryan P.;Grinshpun S.;Villareal M.;Lemasters G. 01-01-2012. Infant origins of childhood asthma associated with specific molds Journal of Allergy and Clinical Immunology, 130 3,

Epstein T.;Bernstein D.;Levin L.;Khurana Hershey G.;Ryan P.;Reponen T.;Villareal M.;Lockey J.;Lemasters G. 01-01-2011. Opposing effects of cat and dog ownership and allergic sensitization on eczema in an atopic birth co Journal of Pediatrics, 158 2,

Codispoti C.;Levin L.;LeMasters G.;Ryan P.;Reponen T.;Villareal M.;Burkle J.;Stanforth S.;Lockey J.;Khurana Hershey G.;Bernstein D. 01-01-2010. Breast-feeding, aeroallergen sensitization, and environmental exposures during infancy are determina Journal of Allergy and Clinical Immunology, 125 5,

Iossifova Y.;Reponen T.;Ryan P.;Levin L.;Bernstein D.;Lockey J.;Hershey G.;Villareal M.;Lemasters G. 01-01-2009. Mold exposure during infancy as a predictor of potential asthma development Annals of Allergy, Asthma and Immunology, 102 2, 131-137

Schroer K.;Biagini Myers J.;Ryan P.;LeMasters G.;Bernstein D.;Villareal M.;Lockey J.;Reponen T.;Grinshpun S.;Khurana Hershey G. 01-01-2009. Associations between Multiple Environmental Exposures and Glutathione S-transferase P1 on Persistent Journal of Pediatrics, 154 3,

Smith A.M.;Bernstein D.I.;LeMasters G.K.;Huey N.L.;Ericksen M.;Villareal M.;Lockey J.;Khurana Hershey G.K. 01-01-2008. Environmental Tobacco Smoke and Interleukin 4 Polymorphism (C-589T) Gene: Environment Interaction In Journal of Pediatrics, 152 5,

Vesper S.;McKinstry C.;Haugland R.;Iossifova Y.;Lemasters G.;Levin L.;Khurana Hershey G.;Villareal M.;Bernstein D.;Lockey J.;Reponen T. 01-01-2007. Relative moldiness index as predictor of childhood respiratory illness Journal of Exposure Science and Environmental Epidemiology, 17 1, 88-94

Cho S.;Reponen T.;LeMasters G.;Levin L.;Huang J.;Meklin T.;Ryan P.;Villareal M.;Bernstein D. 01-01-2006. Mold damage in homes and wheezing in infants Annals of Allergy, Asthma and Immunology, 97 4, 539-545

White J.;Levin L.;Villareal M.;Murphy K.;Biagini R.;Wellinghoff L.;St. Clair H.;Bernstein D. 01-01-2005. Lack of correlation between regional pollen counts and percutaneous reactivity to tree pollen extrac Annals of Allergy, Asthma and Immunology, 94 2, 240-246

Lang D.;Visintainer P.;Howland W.;Stein M.;Villareal M. 01-01-2000. Survey of the extent and nature of care for adults and older adults by Allergy/Immunology practition Annals of Allergy, Asthma and Immunology, 85 2, 106-110