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Christy K. Holland, PhD

Professor

Division of Cardiovascular Diseases; Director, Image-Guided Ultrasound Therapeutics Laboratories; Scientific Director, Heart, Lung, and Vascular Institute

Internal Medicine | College of Medicine

Education/Credentials
  • : University of Freiburg
  • Bachelor's Degree: Wellesley College
  • Master's Degree: Yale University
  • Master's Degree: Yale University
  • Doctoral Degree: Yale University
  • Fellowship: Yale University
Contact Information
Research Interests

  • Bioeffects of Diagnostic and Therapeutic Ultrasound
  • Acoustic Cavitation
  • New Diagnostic imaging Techniques for the Early Detection of Vascular Disease and Ischemic Injury to Brain

Summary

Christy K. Holland, PhD, attended Wellesley College where she completed a double major (BA) in Physics and Music in 1983.  She completed M.S.(1985), M.Phil. (1986), and Ph.D. (1988) degrees at Yale University in Engineering and Applied Science.  She is currently a Professor in both the College of Medicine and the College of Engineering and Applied Sciences at the University of Cincinnati (UC) with joint appointments in the Department of Internal Medicine, Division of Cardiovascular Health and Disease, and the Department of Biomedical Engineering (BME).  Prof. Holland serves as Scientific Director of the Heart, Lung, and Vascular Institute, a key component of efforts to align the UC College of Medicine and UC Health efforts around research, education, and clinical programs.  She is a fellow of the Acoustical Society of America, the American Institute of Ultrasound in Medicine, the American Institute for Medical and Biological Engineering, and the Executive Leadership in Academic Medicine®. Prof. Holland continues to serve as Editor-in-Chief of Ultrasound in Medicine and Biology, the official Journal of the World Federation for Ultrasound in Medicine and Biology, a post she assumed in 2006.  She served as President of the Acoustical Society of America from 2015 to 2017.  She is actively involved in teaching biomedical engineering and biomedical ultrasound in the BME undergraduate and graduate curricula and received teaching awards in the UC Colleges of Engineering and Medicine in 2008 and 2009.  She served as the Director of Graduate Studies for BME in 2007-2009.  She mentors and advises students within and outside of BME educational programs.  Prof. Holland’s research interests include ultrasound-enhanced thrombolysis for stroke therapy, ultrasound-mediated drug delivery, bioeffects of diagnostic and therapeutic ultrasound, and acoustic cavitation.  She directs the Image-guided Ultrasound Therapeutics Laboratories in the UC Cardiovascular Center, which focus on applications of biomedical ultrasound including sonothrombolysis, ultrasound-mediated drug and bioactive gas delivery, development of echogenic liposomes, early detection of cardiovascular diseases, and ultrasound-image guided tumor ablation.  Prof. Holland has gained wide recognition at UC, nationally and internationally for her excellence and contributions in ultrasound research, published in more than 115 scientific publications and 8 patents. 

Peer Reviewed Publications

Lattwein, Kirby R; Shekhar, Himanshu; van Wamel, Willem J B; Gonzalez, Tammy; Herr, Andrew B; Holland, Christy K; Kooiman, Klazina 2018. An in vitro proof-of-principle study of sonobactericide. Scientific reports, 8 1, 3411

Shekhar, Himanshu; Smith, Nathaniel J; Raymond, Jason L; Holland, Christy K 2018. Effect of Temperature on the Size Distribution, Shell Properties, and Stability of Definity®. Ultrasound in medicine & biology, 44 2, 434-446

Beigel, John H; Tebas, Pablo; Elie-Turenne, Marie-Carmelle; Bajwa, Ednan; Bell, Todd E; Cairns, Charles B; Shoham, Shmuel; Deville, Jaime G; Feucht, Eric; Feinberg, Judith; Luke, Thomas; Raviprakash, Kanakatte; Danko, Janine; O'Neil, Dorothy; Metcalf, Julia A; King, Karen; Burgess, Timothy H; Aga, Evgenia; Lane, H Clifford; Hughes, Michael D; Davey, Richard T 2017. Immune plasma for the treatment of severe influenza: an open-label, multicentre, phase 2 randomised study. The Lancet. Respiratory medicine, 5 6, 500-511

Huang, Shenwen; Shekhar, Himanshu; Holland, Christy K 2017. Comparative lytic efficacy of rt-PA and ultrasound in porcine versus human clots. PloS one, 12 5, e0177786

Shekhar, Himanshu; Bader, Kenneth B; Huang, Shenwen; Peng, Tao; Huang, Shaoling; McPherson, David D; Holland, Christy K 2017. In vitro thrombolytic efficacy of echogenic liposomes loaded with tissue plasminogen activator and octafluoropropane gas. Physics in medicine and biology, 62 2, 517-538

Bader, Kenneth B; Bouchoux, Guillaume; Holland, Christy K 2016. Sonothrombolysis. Advances in experimental medicine and biology, 880 , 339-62

Bader, Kenneth B; Crowe, Michael J; Raymond, Jason L; Holland, Christy K 2016. Effect of Frequency-Dependent Attenuation on Predicted Histotripsy Waveforms in Tissue-Mimicking Phantoms. Ultrasound in medicine & biology, 42 7, 1701-5

Bader, Kenneth B; Haworth, Kevin J; Shekhar, Himanshu; Maxwell, Adam D; Peng, Tao; McPherson, David D; Holland, Christy K 2016. Efficacy of histotripsy combined with rt-PA in vitro. Physics in medicine and biology, 61 14, 5253-74

Bader, Kenneth B; Holland, Christy K 2016. Predicting the growth of nanoscale nuclei by histotripsy pulses. Physics in medicine and biology, 61 7, 2947-66

Haworth, Kevin J; Raymond, Jason L; Radhakrishnan, Kirthi; Moody, Melanie R; Huang, Shao-Ling; Peng, Tao; Shekhar, Himanshu; Klegerman, Melvin E; Kim, Hyunggun; McPherson, David D; Holland, Christy K 2016. Erratum to: "Trans-stent B-mode Ultrasound and Passive Cavitation Imaging" in Ultrasound Med Biol 2016;42(2):518-527. Ultrasound in medicine & biology, 42 5, 1244

Haworth, Kevin J; Raymond, Jason L; Radhakrishnan, Kirthi; Moody, Melanie R; Huang, Shao-Ling; Peng, Tao; Shekhar, Himanshu; Klegerman, Melvin E; Kim, Hyunggun; McPherson, David D; Holland, Christy K 2016. Trans-Stent B-Mode Ultrasound and Passive Cavitation Imaging. Ultrasound in medicine & biology, 42 2, 518-27

Kandadai, Madhuvanthi A; Mukherjee, Prithviraj; Shekhar, Himanshu; Shaw, George J; Papautsky, Ian; Holland, Christy K 2016. Microfluidic manufacture of rt-PA -loaded echogenic liposomes. Biomedical microdevices, 18 3, 48

Klegerman, Melvin E; Naji, Ali K; Haworth, Kevin J; Zou, Yuejiao; Golunski, Eva; Peng, Tao; Britton, George L; Huang, Shao-Ling; Holland, Christy K; McPherson, David D 2016. Ultrasound-enhanced bevacizumab release from echogenic liposomes for inhibition of atheroma progression. Journal of liposome research, 26 1, 47-56

Radhakrishnan, Kirthi; Holland, Christy K; Haworth, Kevin J 2016. Scavenging dissolved oxygen via acoustic droplet vaporization. Ultrasonics sonochemistry, 31 , 394-403

Raymond, Jason L; Luan, Ying; Peng, Tao; Huang, Shao-Ling; McPherson, David D; Versluis, Michel; de Jong, Nico; Holland, Christy K 2016. Loss of gas from echogenic liposomes exposed to pulsed ultrasound. Physics in medicine and biology, 61 23, 8321-8339

Sutton, J T; Haworth, K J; Shanmukhappa, S K; Moody, M R; Klegerman, M E; Griffin, J K; Patton, D M; McPherson, D D; Holland, C K 2016. Delivery of bevacizumab to atheromatous porcine carotid tissue using echogenic liposomes. Drug delivery, 23 9, 3594-3605

Bader, Kenneth B; Bouchoux, Guillaume; Peng, Tao; Klegerman, Melvin E; McPherson, David D; Holland, Christy K 2015. Thrombolytic efficacy and enzymatic activity of rt-PA-loaded echogenic liposomes. Journal of thrombosis and thrombolysis, ,

Bader, Kenneth B; Gruber, Matthew J; Holland, Christy K 2015. Shaken and stirred: mechanisms of ultrasound-enhanced thrombolysis. Ultrasound in medicine & biology, 41 1, 187-96

Haworth, Kevin J; Salgaonkar, Vasant A; Corregan, Nicholas M; Holland, Christy K; Mast, T Douglas 2015. Using Passive Cavitation Images to Classify High-Intensity Focused Ultrasound Lesions. Ultrasound in medicine & biology, 41 9, 2420-34

Holland, C 2015. WE-D-210-03: Microbubble Pumps: Â Ultrasound Theragnostic Agents. Medical physics, 42 6, 3672

Kandadai, Madhuvanthi A; Meunier, Jason M; Hart, Kimberley; Holland, Christy K; Shaw, George J 2015. Plasmin-loaded echogenic liposomes for ultrasound-mediated thrombolysis. Translational stroke research, 6 1, 78-87

Radhakrishnan, Kirthi; Haworth, Kevin J; Peng, Tao; McPherson, David D; Holland, Christy K 2015. Loss of echogenicity and onset of cavitation from echogenic liposomes: pulse repetition frequency independence. Ultrasound in medicine & biology, 41 1, 208-21

Raymond, Jason L; Luan, Ying; van Rooij, Tom; Kooiman, Klazina; Huang, Shao-Ling; McPherson, David D; Versluis, Michel; de Jong, Nico; Holland, Christy K 2015. Impulse response method for characterization of echogenic liposomes. The Journal of the Acoustical Society of America, 137 4, 1693-703

Bouchoux, Guillaume; Shivashankar, Ravishankar; Abruzzo, Todd A; Holland, Christy K 2014. In silico study of low-frequency transcranial ultrasound fields in acute ischemic stroke patients. Ultrasound in medicine & biology, 40 6, 1154-66

Gruber, Matthew J; Bader, Kenneth B; Holland, Christy K 2014. Cavitation thresholds of contrast agents in an in vitro human clot model exposed to 120-kHz ultrasound. The Journal of the Acoustical Society of America, 135 2, 646-53

Haworth, Kevin J; Weidner, Christopher R; Abruzzo, Todd A; Shearn, Jason T; Holland, Christy K 2014. Mechanical properties and fibrin characteristics of endovascular coil-clot complexes: relevance to endovascular cerebral aneurysm repair paradigms. Journal of neurointerventional surgery, ,

Kim, Hyunggun; Britton, George L; Peng, Tao; Holland, Christy K; McPherson, David D; Huang, Shao-Ling 2014. Nitric oxide-loaded echogenic liposomes for treatment of vasospasm following subarachnoid hemorrhage. International journal of nanomedicine, 9 , 155-65

Raymond, Jason L; Haworth, Kevin J; Bader, Kenneth B; Radhakrishnan, Kirthi; Griffin, Joseph K; Huang, Shao-Ling; McPherson, David D; Holland, Christy K 2014. Broadband attenuation measurements of phospholipid-shelled ultrasound contrast agents. Ultrasound in medicine & biology, 40 2, 410-21

Sutton, J T; Raymond, J L; Verleye, M C; Pyne-Geithman, G J; Holland, C K 2014. Pulsed ultrasound enhances the delivery of nitric oxide from bubble liposomes to ex vivo porcine carotid tissue. International journal of nanomedicine, 9 , 4671-83

Bader, K. B.; Holland, C. K. 2013. Gauging the likelihood of stable cavitation from ultrasound contrast agents Phys Med Biol, 58 1 , 127-44

Bader, Kenneth B; Holland, Christy K 2013. Gauging the likelihood of stable cavitation from ultrasound contrast agents. Physics in medicine and biology, 58 1, 127-44

Haworth, K. J.; Salgaonkar, V. A.; Corregan, N. M.; Holland, C. K.; Mast, T. D. 2013. Spatial specificity and sensitivity of passive cavitation imaging for monitoring high-intensity focused ultrasound thermal ablation in ex vivo bovine liver J Acoust Soc Am, 133 5 , 3263

Kopechek, J. A.; Haworth, K. J.; Radhakrishnan, K.; Huang, S. L.; Klegerman, M. E.; McPherson, D. D.; Holland, C. K. 2013. The impact of bubbles on measurement of drug release from echogenic liposomes Ultrason Sonochem, 20 4 , 1121-30

Kopechek, Jonathan A; Haworth, Kevin J; Radhakrishnan, Kirthi; Huang, Shao-Ling; Klegerman, Melvin E; McPherson, David D; Holland, Christy K 2013. The impact of bubbles on measurement of drug release from echogenic liposomes. Ultrasonics sonochemistry, 20 4, 1121-30

Radhakrishnan, Kirthi; Bader, Kenneth B; Haworth, Kevin J; Kopechek, Jonathan A; Raymond, Jason L; Huang, Shao-Ling; McPherson, David D; Holland, Christy K 2013. Relationship between cavitation and loss of echogenicity from ultrasound contrast agents. Physics in medicine and biology, 58 18, 6541-63

Sutton, J. T.; Ivancevich, N. M.; Perrin, S. R., Jr.; Vela, D. C.; Holland, C. K. 2013. Clot retraction affects the extent of ultrasound-enhanced thrombolysis in an ex vivo porcine thrombosis model Ultrasound Med Biol, 39 5 , 813-24

Sutton, J. T.; Haworth, K. J.; Pyne-Geithman, G.; Holland, C. K. 2013. Ultrasound-mediated drug delivery for cardiovascular disease Expert Opin Drug Deliv, 10 5 , 573-92

Sutton, Jonathan T; Haworth, Kevin J; Pyne-Geithman, Gail; Holland, Christy K 2013. Ultrasound-mediated drug delivery for cardiovascular disease. Expert opinion on drug delivery, 10 5, 573-92

Sutton, Jonathan T; Ivancevich, Nikolas M; Perrin, Stephen R; Vela, Deborah C; Holland, Christy K 2013. Clot retraction affects the extent of ultrasound-enhanced thrombolysis in an ex vivo porcine thrombosis model. Ultrasound in medicine & biology, 39 5, 813-24

Bouchoux, G.; Bader, K. B.; Korfhagen, J. J.; Raymond, J. L.; Shivashankar, R.; Abruzzo, T. A.; Holland, C. K. 2012. Experimental validation of a finite-difference model for the prediction of transcranial ultrasound fields based on CT images Phys Med Biol, 57 23 , 8005-22

Bouchoux, Guillaume; Bader, Kenneth B; Korfhagen, Joseph J; Raymond, Jason L; Shivashankar, Ravishankar; Abruzzo, Todd A; Holland, Christy K 2012. Experimental validation of a finite-difference model for the prediction of transcranial ultrasound fields based on CT images. Physics in medicine and biology, 57 23, 8005-22

Haworth, K. J.; Mast, T. D.; Radhakrishnan, K.; Burgess, M. T.; Kopechek, J. A.; Huang, S. L.; McPherson, D. D.; Holland, C. K. 2012. Passive imaging with pulsed ultrasound insonations J Acoust Soc Am, 132 1 , 544-53

Haworth, Kevin J; Mast, T Douglas; Radhakrishnan, Kirthi; Burgess, Mark T; Kopechek, Jonathan A; Huang, Shao-Ling; McPherson, David D; Holland, Christy K 2012. Passive imaging with pulsed ultrasound insonations. The Journal of the Acoustical Society of America, 132 1, 544-53

Huppert, Jill S; Reed, Jennifer L; Munafo, Jennifer Knopf; Ekstrand, Rachel; Gillespie, Gordon; Holland, Carolyn; Britto, Maria T 2012. Improving notification of sexually transmitted infections: a quality improvement project and planned experiment. Pediatrics, 130 2, e415-22

Laing, S. T.; Moody, M. R.; Kim, H.; Smulevitz, B.; Huang, S. L.; Holland, C. K.; McPherson, D. D.; Klegerman, M. E. 2012. Thrombolytic efficacy of tissue plasminogen activator-loaded echogenic liposomes in a rabbit thrombus model Thromb Res, 130 4 , 629-35

Radhakrishnan, K.; Haworth, K. J.; Huang, S. L.; Klegerman, M. E.; McPherson, D. D.; Holland, C. K. 2012. Stability of echogenic liposomes as a blood pool ultrasound contrast agent in a physiologic flow phantom Ultrasound Med Biol, 38 11 , 1970-81

Radhakrishnan, Kirthi; Haworth, Kevin J; Huang, Shao-Ling; Klegerman, Melvin E; McPherson, David D; Holland, Christy K 2012. Stability of echogenic liposomes as a blood pool ultrasound contrast agent in a physiologic flow phantom. Ultrasound in medicine & biology, 38 11, 1970-81

Hitchcock, K. E.; Ivancevich, N. M.; Haworth, K. J.; Caudell Stamper, D. N.; Vela, D. C.; Sutton, J. T.; Pyne-Geithman, G. J.; Holland, C. K. 2011. Ultrasound-enhanced rt-PA thrombolysis in an ex vivo porcine carotid artery model Ultrasound Med Biol, 37 8 , 1240-51

Hitchcock, Kathryn E; Ivancevich, Nikolas M; Haworth, Kevin J; Caudell Stamper, Danielle N; Vela, Deborah C; Sutton, Jonathan T; Pyne-Geithman, Gail J; Holland, Christy K 2011. Ultrasound-enhanced rt-PA thrombolysis in an ex vivo porcine carotid artery model. Ultrasound in medicine & biology, 37 8, 1240-51

Kopechek, J. A.; Haworth, K. J.; Raymond, J. L.; Douglas Mast, T.; Perrin, S. R.; Klegerman, M. E.; Huang, S.; Porter, T. M.; McPherson, D. D.; Holland, C. K. 2011. Acoustic characterization of echogenic liposomes: frequency-dependent attenuation and backscatter J Acoust Soc Am, 130 5 , 3472-81

Kopechek, Jonathan A; Haworth, Kevin J; Raymond, Jason L; Douglas Mast, T; Perrin, Stephen R; Klegerman, Melvin E; Huang, Shaoling; Porter, Tyrone M; McPherson, David D; Holland, Christy K 2011. Acoustic characterization of echogenic liposomes: frequency-dependent attenuation and backscatter. The Journal of the Acoustical Society of America, 130 5, 3472-81

Laing, S. T.; Moody, M.; Smulevitz, B.; Kim, H.; Kee, P.; Huang, S.; Holland, C. K.; McPherson, D. D. 2011. Ultrasound-enhanced thrombolytic effect of tissue plasminogen activator-loaded echogenic liposomes in an in vivo rabbit aorta thrombus model--brief report Arterioscler Thromb Vasc Biol, 31 6 , 1357-9

Meunier, J. M.; Holland, C. K.; Porter, T. M.; Lindsell, C. J.; Shaw, G. J. 2011. Combination treatment with rt-PA is more effective than rt-PA alone in an in vitro human clot model Curr Neurovasc Res, 8 4 , 305-12

Meunier, Jason M; Holland, Christy K; Porter, Tyrone M; Lindsell, Christopher J; Shaw, George J 2011. Combination treatment with rt-PA is more effective than rt-PA alone in an in vitro human clot model. Current neurovascular research, 8 4, 305-12

Britton, G. L.; Kim, H.; Kee, P. H.; Aronowski, J.; Holland, C. K.; McPherson, D. D.; Huang, S. L. 2010. In vivo therapeutic gas delivery for neuroprotection with echogenic liposomes Circulation, 122 16 , 1578-87

Herbst, S. M.; Klegerman, M. E.; Kim, H.; Qi, J.; Shelat, H.; Wassler, M.; Moody, M. R.; Yang, C. M.; Ge, X.; Zou, Y.; Kopechek, J. A.; Clubb, F. J.; Kraemer, D. C.; Huang, S.; Holland, C. K.; McPherson, D. D.; Geng, Y. J. 2010. Delivery of stem cells to porcine arterial wall with echogenic liposomes conjugated to antibodies against CD34 and intercellular adhesion molecule-1 Mol Pharm, 7 1 , 3-11

Hitchcock, K. E.; Caudell, D. N.; Sutton, J. T.; Klegerman, M. E.; Vela, D.; Pyne-Geithman, G. J.; Abruzzo, T.; Cyr, P. E.; Geng, Y. J.; McPherson, D. D.; Holland, C. K. 2010. Ultrasound-enhanced delivery of targeted echogenic liposomes in a novel ex vivo mouse aorta model J Control Release, 144 3 , 288-95

Hitchcock, K. E.; Holland, C. K. 2010. Ultrasound-assisted thrombolysis for stroke therapy: better thrombus break-up with bubbles Stroke, 41 10 Suppl , S50-3

Hitchcock, Kathryn E; Caudell, Danielle N; Sutton, Jonathan T; Klegerman, Melvin E; Vela, Deborah; Pyne-Geithman, Gail J; Abruzzo, Todd; Cyr, Peppar E P; Geng, Yong-Jian; McPherson, David D; Holland, Christy K 2010. Ultrasound-enhanced delivery of targeted echogenic liposomes in a novel ex vivo mouse aorta model. Journal of controlled release : official journal of the Controlled Release Society, 144 3, 288-95

Hitchcock, Kathryn E; Holland, Christy K 2010. Ultrasound-assisted thrombolysis for stroke therapy: better thrombus break-up with bubbles. Stroke; a journal of cerebral circulation, 41 10 Suppl, S50-3

Klegerman, M. E.; Wassler, M.; Huang, S. L.; Zou, Y.; Kim, H.; Shelat, H. S.; Holland, C. K.; Geng, Y. J.; McPherson, D. D. 2010. Liposomal modular complexes for simultaneous targeted delivery of bioactive gases and therapeutics J Control Release, 142 3 , 326-31

Kopechek, J. A.; Kim, H.; McPherson, D. D.; Holland, C. K. 2010. Calibration of the 1-MHz Sonitron ultrasound system Ultrasound Med Biol, 36 10 , 1762-6

Kopechek, Jonathan A; Kim, Hyunggun; McPherson, David D; Holland, Christy K 2010. Calibration of the 1-MHz Sonitron ultrasound system. Ultrasound in medicine & biology, 36 10, 1762-6

Laing, S. T.; Kim, H.; Kopechek, J. A.; Parikh, D.; Huang, S.; Klegerman, M. E.; Holland, C. K.; McPherson, D. D. 2010. Ultrasound-mediated delivery of echogenic immunoliposomes to porcine vascular smooth muscle cells in vivo J Liposome Res, 20 2 , 160-7

Shaw, G. J.; Meunier, J. M.; Lindsell, C. J.; Pancioli, A. M.; Holland, C. K. 2010. Making the right choice: optimizing rt-PA and eptifibatide lysis, an in vitro study Thromb Res, 126 4 , e305-11

Shaw, George J; Meunier, Jason M; Lindsell, Christopher J; Pancioli, Arthur M; Holland, Christy K 2010. Making the right choice: optimizing rt-PA and eptifibatide lysis, an in vitro study. Thrombosis research, 126 4, e305-11

Smith, D. A.; Vaidya, S. S.; Kopechek, J. A.; Huang, S. L.; Klegerman, M. E.; McPherson, D. D.; Holland, C. K. 2010. Ultrasound-triggered release of recombinant tissue-type plasminogen activator from echogenic liposomes Ultrasound Med Biol, 36 1 , 145-57

Smith, Denise A B; Vaidya, Sampada S; Kopechek, Jonathan A; Huang, Shao-Ling; Klegerman, Melvin E; McPherson, David D; Holland, Christy K 2010. Ultrasound-triggered release of recombinant tissue-type plasminogen activator from echogenic liposomes. Ultrasound in medicine & biology, 36 1, 145-57

Holland, C. K.; McPherson, D. D. 2009. Echogenic Lipsomes for Targeted Drug Delivery Proc IEEE Int Symp Biomed Imaging, 2009 3 , 755-758

Holland, Christy K; McPherson, David D 2009. ECHOGENIC LIPSOMES FOR TARGETED DRUG DELIVERY. Proceedings / IEEE International Symposium on Biomedical Imaging: from nano to macro. IEEE International Symposium on Biomedical Imaging, 2009 , 755-758

Meunier, J. M.; Holland, C. K.; Pancioli, A. M.; Lindsell, C. J.; Shaw, G. J. 2009. Effect of low frequency ultrasound on combined rt-PA and eptifibatide thrombolysis in human clots Thromb Res, 123 3 , 528-36

Meunier, Jason M; Holland, Christy K; Pancioli, Arthur M; Lindsell, Christopher J; Shaw, George J 2009. Effect of low frequency ultrasound on combined rt-PA and eptifibatide thrombolysis in human clots. Thrombosis research, 123 3, 528-36

Salgaonkar, V. A.; Datta, S.; Holland, C. K.; Mast, T. D. 2009. Passive cavitation imaging with ultrasound arrays J Acoust Soc Am, 126 6 , 3071-83

Salgaonkar, Vasant A; Datta, Saurabh; Holland, Christy K; Mast, T Douglas 2009. Passive cavitation imaging with ultrasound arrays. The Journal of the Acoustical Society of America, 126 6, 3071-83

Shaw, G. J.; Meunier, J. M.; Huang, S. L.; Lindsell, C. J.; McPherson, D. D.; Holland, C. K. 2009. Ultrasound-enhanced thrombolysis with tPA-loaded echogenic liposomes Thromb Res, 124 3 , 306-10

Shaw, George J; Meunier, Jason M; Huang, Shao-Ling; Lindsell, Christopher J; McPherson, David D; Holland, Christy K 2009. Ultrasound-enhanced thrombolysis with tPA-loaded echogenic liposomes. Thrombosis research, 124 3, 306-10

Ammi, A. Y.; Mast, T. D.; Huang, I. H.; Abruzzo, T. A.; Coussios, C. C.; Shaw, G. J.; Holland, C. K. 2008. Characterization of ultrasound propagation through ex-vivo human temporal bone Ultrasound Med Biol, 34 10 , 1578-89

Ammi, Azzdine Y; Mast, T Douglas; Huang, I-Hua; Abruzzo, Todd A; Coussios, Constantin-C; Shaw, George J; Holland, Christy K 2008. Characterization of ultrasound propagation through ex-vivo human temporal bone. Ultrasound in medicine & biology, 34 10, 1578-89

Datta, S.; Coussios, C. C.; Ammi, A. Y.; Mast, T. D.; de Courten-Myers, G. M.; Holland, C. K. 2008. Ultrasound-enhanced thrombolysis using Definity as a cavitation nucleation agent Ultrasound Med Biol, 34 9 , 1421-33

Datta, Saurabh; Coussios, Constantin-C; Ammi, Azzdine Y; Mast, T Douglas; de Courten-Myers, Gabrielle M; Holland, Christy K 2008. Ultrasound-enhanced thrombolysis using Definity as a cavitation nucleation agent. Ultrasound in medicine & biology, 34 9, 1421-33

Holland, C. K.; Vaidya, S. S.; Datta, S.; Coussios, C. C.; Shaw, G. J. 2008. Ultrasound-enhanced tissue plasminogen activator thrombolysis in an in vitro porcine clot model Thromb Res, 121 5 , 663-73

Holland, Christy K; Vaidya, Sampada S; Datta, Saurabh; Coussios, Constantin-C; Shaw, George J 2008. Ultrasound-enhanced tissue plasminogen activator thrombolysis in an in vitro porcine clot model. Thrombosis research, 121 5, 663-73

Kee, P. H.; Abruzzo, T. A.; Smith, D. A.; Kopechek, J. A.; Wang, B.; Huang, S. L.; MacDonald, R. C.; Holland, C. K.; McPherson, D. D. 2008. Synthesis, acoustic stability, and pharmacologic activities of papaverine-loaded echogenic liposomes for ultrasound controlled drug delivery J Liposome Res, 18 4 , 263-77

Kopechek, J. A.; Abruzzo, T. M.; Wang, B.; Chrzanowski, S. M.; Smith, D. A.; Kee, P. H.; Huang, S.; Collier, J. H.; McPherson, D. D.; Holland, C. K. 2008. Ultrasound-mediated release of hydrophilic and lipophilic agents from echogenic liposomes J Ultrasound Med, 27 11 , 1597-606

Kopechek, Jonathan A; Abruzzo, Todd M; Wang, Boyu; Chrzanowski, Stephen M; Smith, Denise A B; Kee, Patrick H; Huang, Shaoling; Collier, Joel H; McPherson, David D; Holland, Christy K 2008. Ultrasound-mediated release of hydrophilic and lipophilic agents from echogenic liposomes. Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 27 11, 1597-606

Mast, T Douglas; Salgaonkar, Vasant A; Karunakaran, Chandrapriya; Besse, John A; Datta, Saurabh; Holland, Christy K 2008. Acoustic emissions during 3.1 MHz ultrasound bulk ablation in vitro. Ultrasound in medicine & biology, 34 9, 1434-48

Mast, T. D.; Salgaonkar, V. A.; Karunakaran, C.; Besse, J. A.; Datta, S.; Holland, C. K. 2008. Acoustic emissions during 3.1 MHz ultrasound bulk ablation in vitro Ultrasound Med Biol, 34 9 , 1434-48

Miller, D. L.; Averkiou, M. A.; Brayman, A. A.; Everbach, E. C.; Holland, C. K.; Wible, J. H., Jr.; Wu, J. 2008. Bioeffects considerations for diagnostic ultrasound contrast agents J Ultrasound Med, 27 4 , 611-32; quiz 633-6

Shaw, G. J.; Meunier, J. M.; Lindsell, C. J.; Holland, C. K. 2008. Tissue plasminogen activator concentration dependence of 120 kHz ultrasound-enhanced thrombolysis Ultrasound Med Biol, 34 11 , 1783-92

Shaw, George J; Meunier, Jason M; Lindsell, Christopher J; Holland, Christy K 2008. Tissue plasminogen activator concentration dependence of 120 kHz ultrasound-enhanced thrombolysis. Ultrasound in medicine & biology, 34 11, 1783-92

Wang, Y.; Krishnamoorthy, M.; Banerjee, R.; Zhang, J.; Rudich, S.; Holland, C.; Arend, L.; Roy-Chaudhury, P. 2008. Venous stenosis in a pig arteriovenous fistula model--anatomy, mechanisms and cellular phenotypes Nephrol Dial Transplant, 23 2 , 525-33

Wang, Yang; Krishnamoorthy, Mahesh; Banerjee, Rupak; Zhang, Jianhua; Rudich, Steven; Holland, Christy; Arend, Lois; Roy-Chaudhury, Prabir 2008. Venous stenosis in a pig arteriovenous fistula model--anatomy, mechanisms and cellular phenotypes. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 23 2, 525-33

Zhou, X.; Espy-Wilson, C. Y.; Boyce, S.; Tiede, M.; Holland, C.; Choe, A. 2008. A magnetic resonance imaging-based articulatory and acoustic study of "retroflex" and "bunched" American English /r J Acoust Soc Am, 123 6 , 4466-81

Meunier, J. M.; Holland, C. K.; Lindsell, C. J.; Shaw, G. J. 2007. Duty cycle dependence of ultrasound enhanced thrombolysis in a human clot model Ultrasound Med Biol, 33 4 , 576-83

Meunier, Jason M; Holland, Christy K; Lindsell, Christopher J; Shaw, George J 2007. Duty cycle dependence of ultrasound enhanced thrombolysis in a human clot model. Ultrasound in medicine & biology, 33 4, 576-83

Nahirnyak, V.; Mast, T. D.; Holland, C. K. 2007. Ultrasound-induced thermal elevation in clotted blood and cranial bone Ultrasound Med Biol, 33 8 , 1285-95

Nahirnyak, Volodymyr; Mast, T Douglas; Holland, Christy K 2007. Ultrasound-induced thermal elevation in clotted blood and cranial bone. Ultrasound in medicine & biology, 33 8, 1285-95

Shaw, G. J.; Dhamija, A.; Bavani, N.; Wagner, K. R.; Holland, C. K. 2007. Arrhenius temperature dependence of in vitro tissue plasminogen activator thrombolysis Phys Med Biol, 52 11 , 2953-67

Shaw, George J; Dhamija, Ashima; Bavani, Nazli; Wagner, Kenneth R; Holland, Christy K 2007. Arrhenius temperature dependence of in vitro tissue plasminogen activator thrombolysis. Physics in medicine and biology, 52 11, 2953-67

Smith, D. A.; Porter, T. M.; Martinez, J.; Huang, S.; MacDonald, R. C.; McPherson, D. D.; Holland, C. K. 2007. Destruction thresholds of echogenic liposomes with clinical diagnostic ultrasound Ultrasound Med Biol, 33 5 , 797-809

Smith, Denise A B; Porter, Tyrone M; Martinez, Janet; Huang, Shaoling; MacDonald, Robert C; McPherson, David D; Holland, Christy K 2007. Destruction thresholds of echogenic liposomes with clinical diagnostic ultrasound. Ultrasound in medicine & biology, 33 5, 797-809

Tiukinhoy-Laing, S. D.; Huang, S.; Klegerman, M.; Holland, C. K.; McPherson, D. D. 2007. Ultrasound-facilitated thrombolysis using tissue-plasminogen activator-loaded echogenic liposomes Thromb Res, 119 6 , 777-84

Datta, S.; Coussios, C. C.; McAdory, L. E.; Tan, J.; Porter, T.; De Courten-Myers, G.; Holland, C. K. 2006. Correlation of cavitation with ultrasound enhancement of thrombolysis Ultrasound Med Biol, 32 8 , 1257-67

Datta, Saurabh; Coussios, Constantin-C; McAdory, Louis E; Tan, Jun; Porter, Tyrone; De Courten-Myers, Gabrielle; Holland, Christy K 2006. Correlation of cavitation with ultrasound enhancement of thrombolysis. Ultrasound in medicine & biology, 32 8, 1257-67

More, S. R.; Lim, T. C.; Li, M.; Holland, C. K.; Boyce, S. E.; Lee, J. H. 2006. Acoustic noise characteristics of a 4 Telsa MRI scanner J Magn Reson Imaging, 23 3 , 388-97

More, Shashikant R; Lim, Teik C; Li, Mingfeng; Holland, Christy K; Boyce, Suzanne E; Lee, Jing-Huei 2006. Acoustic noise characteristics of a 4 Telsa MRI scanner. Journal of magnetic resonance imaging : JMRI, 23 3, 388-97

Nahirnyak, V. M.; Yoon, S. W.; Holland, C. K. 2006. Acousto-mechanical and thermal properties of clotted blood J Acoust Soc Am, 119 6 , 3766-72

Nahirnyak, Volodymyr M; Yoon, Suk Wang; Holland, Christy K 2006. Acousto-mechanical and thermal properties of clotted blood. The Journal of the Acoustical Society of America, 119 6, 3766-72

Porter, T. M.; Smith, D. A.; Holland, C. K. 2006. Acoustic techniques for assessing the Optison destruction threshold J Ultrasound Med, 25 12 , 1519-29

Porter, Tyrone M; Smith, Denise A B; Holland, Christy K 2006. Acoustic techniques for assessing the Optison destruction threshold. Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 25 12, 1519-29

Wright, S. W.; Lindsell, C. J.; Hinckley, W. R.; Williams, A.; Holland, C.; Lewis, C. H.; Heimburger, G. 2006. High fidelity medical simulation in the difficult environment of a helicopter: feasibility, self-efficacy and cost BMC Med Educ, 6 4 , 49

Wright, Stewart W; Lindsell, Christopher J; Hinckley, William R; Williams, Annette; Holland, Carolyn; Lewis, Christopher H; Heimburger, Gail 2006. High fidelity medical simulation in the difficult environment of a helicopter: feasibility, self-efficacy and cost. BMC medical education, 6 , 49

Cheng, J. Y.; Shaw, G. J.; Holland, C. K. 2005. In vitro microscopic imaging of enhanced thrombolysis with 120-kHz ultrasound in a human clot model Acoust Res Lett Online, 6 1 , 25-29

Cheng, Jason Y; Shaw, George J; Holland, Christy K 2005. In vitro microscopic imaging of enhanced thrombolysis with 120-kHz ultrasound in a human clot model. Acoustics research letters online : ARLO, 6 1, 25-29

Coussios, C. C.; Holland, C. K.; Jakubowska, L.; Huang, S. L.; MacDonald, R. C.; Nagaraj, A.; McPherson, D. D. 2004. In vitro characterization of liposomes and Optison by acoustic scattering at 3.5 MHz Ultrasound Med Biol, 30 2 , 181-90

Coussios, Constantin-C; Holland, Christy K; Jakubowska, Ludwika; Huang, Shao-Ling; MacDonald, Robert C; Nagaraj, Ashwin; McPherson, David D 2004. In vitro characterization of liposomes and Optison by acoustic scattering at 3.5 MHz. Ultrasound in medicine & biology, 30 2, 181-90

McPherson, D. D.; Holland, C. K. 2003. Seizing the science of ultrasound: beyond imaging and into physiology and therapeutics J Am Coll Cardiol, 41 9 , 1628-30

Taylor, C. R.; Holland, C. K. 2003. Kenneth J. Taylor, MD, PhD, FACP, 1939-2003, pioneer of diagnostic ultrasound imaging J Ultrasound Med, 22 6 , 663-4

Fowlkes, J. B.; Holland, C. K. 2000. Mechanical bioeffects from diagnostic ultrasound: AIUM consensus statements. American Institute of Ultrasound in Medicine J Ultrasound Med, 19 2 , 69-72

Ouanounou, S.; Tomsick, T. A.; Heitsman, C.; Holland, C. K. 1999. Cavernous sinus and inferior petrosal sinus flow signal on three-dimensional time-of-flight MR angiography AJNR Am J Neuroradiol, 20 8 , 1476-81

Ouanounou, S; Tomsick, T A; Heitsman, C; Holland, C K 1999. Cavernous sinus and inferior petrosal sinus flow signal on three-dimensional time-of-flight MR angiography. AJNR. American journal of neuroradiology, 20 8, 1476-81

Holland, C K; Brown, J M; Scoutt, L M; Taylor, K J 1998. Lower extremity volumetric arterial blood flow in normal subjects. Ultrasound in medicine & biology, 24 8, 1079-86

Holland, C. K.; Brown, J. M.; Scoutt, L. M.; Taylor, K. J. 1998. Lower extremity volumetric arterial blood flow in normal subjects Ultrasound Med Biol, 24 8 , 1079-86

Deng, C. X.; Xu, Q.; Apfel, R. E.; Holland, C. K. 1996. In vitro measurements of inertial cavitation thresholds in human blood Ultrasound Med Biol, 22 7 , 939-48

Deng, C. X.; Xu, Q.; Apfel, R. E.; Holland, C. K. 1996. Inertial cavitation produced by pulsed ultrasound in controlled host media J Acoust Soc Am, 100 2 Pt 1 , 1199-208

Holland, C K; Clancy, M J; Taylor, K J; Alderman, J L; Purushothaman, K; McCauley, T R 1996. Volumetric flow estimation in vivo and in vitro using pulsed-Doppler ultrasound. Ultrasound in medicine & biology, 22 5, 591-603

Holland, C K; Deng, C X; Apfel, R E; Alderman, J L; Fernandez, L A; Taylor, K J 1996. Direct evidence of cavitation in vivo from diagnostic ultrasound. Ultrasound in medicine & biology, 22 7, 917-25

Holland, C. K.; Clancy, M. J.; Taylor, K. J.; Alderman, J. L.; Purushothaman, K.; McCauley, T. R. 1996. Volumetric flow estimation in vivo and in vitro using pulsed-Doppler ultrasound Ultrasound Med Biol, 22 5 , 591-603

Holland, C. K.; Deng, C. X.; Apfel, R. E.; Alderman, J. L.; Fernandez, L. A.; Taylor, K. J. 1996. Direct evidence of cavitation in vivo from diagnostic ultrasound Ultrasound Med Biol, 22 7 , 917-25

Brown, J. M.; Hammers, L. W.; Barton, J. W.; Holland, C. K.; Scoutt, L. M.; Pellerito, J. S.; Taylor, K. J. 1995. Quantitative Doppler assessment of acute scrotal inflammation Radiology, 197 2 , 427-31

McCauley, T. R.; Pena, C. S.; Holland, C. K.; Price, T. B.; Gore, J. C. 1995. Validation of volume flow measurements with cine phase-contrast MR imaging for peripheral arterial waveforms J Magn Reson Imaging, 5 6 , 663-8

Reinhold, C.; Hammers, L.; Taylor, C. R.; Quedens-Case, C. L.; Holland, C. K.; Taylor, K. J. 1995. Characterization of focal hepatic lesions with duplex sonography: findings in 198 patients AJR Am J Roentgenol, 164 5 , 1131-5

Dillon, E. H.; Case, C. Q.; Ramos, I. M.; Holland, C. K.; Taylor, K. J. 1993. Endovaginal pulsed and color Doppler in first-trimester pregnancy Ultrasound Med Biol, 19 7 , 517-25

Dillon, E. H.; Case, C. Q.; Ramos, I. M.; Holland, C. K.; Taylor, K. J. 1993. Endovaginal US and Doppler findings after first-trimester abortion Radiology, 186 1 , 87-91

Holland, C. K. 1993. An ethnographic study of nursing culture as an exploration for determining the existence of a system of ritual J Adv Nurs, 18 9 , 1461-70

Holland, C. K.; Taylor, K. J. 1993. Blood flow quantitation: waveform analysis, volume measurement, tumor flow, and the role of color imaging Clin Diagn Ultrasound, 28 2 , 125-39

Crum, L. A.; Roy, R. A.; Dinno, M. A.; Church, C. C.; Apfel, R. E.; Holland, C. K.; Madanshetty, S. I. 1992. Acoustic cavitation produced by microsecond pulses of ultrasound: a discussion of some selected results J Acoust Soc Am, 91 2 , 1113-9

Holland, C. K.; Roy, R. A.; Apfel, R. E.; Crum, L. A. 1992. In vitro detection of cavitation induced by a diagnostic ultrasound system IEEE Trans Ultrason Ferroelectr Freq Control, 39 1 , 95-101

Apfel, R. E.; Holland, C. K. 1991. Gauging the likelihood of cavitation from short-pulse, low-duty cycle diagnostic ultrasound Ultrasound Med Biol, 17 2 , 179-85

Holland, C. K.; Apfel, R. E. 1990. Thresholds for transient cavitation produced by pulsed ultrasound in a controlled nuclei environment J Acoust Soc Am, 88 5 , 2059-69

Holland, C. K.; Apfel, R. E. 1989. An improved theory for the prediction of microcavitation thresholds IEEE Trans Ultrason Ferroelectr Freq Control, 36 2 , 204-8

Atchley, A. A.; Frizzell, L. A.; Apfel, R. E.; Holland, C. K.; Madanshetty, S.; Roy, R. A. 1988. Thresholds for cavitation produced in water by pulsed ultrasound Ultrasonics, 26 5 , 280-5

Lattwein K.;Shekhar H.;Van Wamel W.;Gonzalez T.;Herr A.;Holland C.;Kooiman K. 12-01-2018. An in vitro proof-of-principle study of sonobactericide Scientific Reports, 8 1,

Krishnamoorthy M.K.;Roy-Chaudhury P.;Wang Y.;Holland C.K.;Rigger D.;Choe A.;Banerjee R.K. 12-01-2009. Vascular remodeling of arteriovenous fistula Proceedings of the ASME Summer Bioengineering Conference 2009, SBC2009, PART B, 1077-1078

Kee P.;Abruzzo T.;Smith D.;Kopechek J.;Wang B.;Huang S.;MacDonald R.;Holland C.;McPherson D. 12-01-2008. Synthesis, acoustic stability, and pharmacologic activities of papaverine-loaded echogenic liposomes Journal of Liposome Research, 18 4, 263-277

Holland C.;McPherson D. 11-17-2009. Echogenic lipsomes for targeted drug delivery Proceedings - 2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2009, , 755-758

Haworth K.;Goldstein B.;Mercado-Shekhar K.;Holland C.;Redington A. 10-31-2017. Dissolved oxygen scavenging by acoustic droplet vaporization using intravascular ultrasound IEEE International Ultrasonics Symposium, IUS, ,

Haworth K.J.;Arunkumar P.;Goldstein B.H.;Su H.;Mercado-Shekhar K.P.;Privitera E.M.;Srivastava R.;Holland C.K.;Redington A.N. 10-31-2017. Dissolved oxygen scavenging by acoustic droplet vaporization using intravascular ultrasound IEEE International Ultrasonics Symposium, IUS, ,

Bader K.;Holland C. 10-28-2015. Development of a hybrid finite difference solution of the Westervelt equation using the fast nearfie AIP Conference Proceedings, 1685 ,

Britton G.;Kim H.;Kee P.;Aronowski J.;Holland C.;McPherson D.;Huang S. 10-19-2010. In vivo therapeutic gas delivery for neuroprotection with echogenic liposomes Circulation, 122 16, 1578-1587

Laing S.;Moody M.;Kim H.;Smulevitz B.;Huang S.;Holland C.;McPherson D.;Klegerman M. 10-01-2012. Thrombolytic efficacy of tissue plasminogen activator-loaded echogenic liposomes in a rabbit thrombu Thrombosis Research, 130 4, 629-635

Mast T.;Salgaonkar V.;Karunakaran C.;Besse J.;Datta S.;Holland C. 09-24-2007. Measurements of cavitation dose, echogenicity, and temperature during ultrasound ablation AIP Conference Proceedings, 911 , 335-341

Salgaonkar V.;Karunakaran C.;Besse J.;Heinlein G.;Datta S.;Holland C.;Mast T. 08-31-2007. Image-guided Ex vivo liver ablation by unfocused ultrasound using passive cavitation detection Progress in Biomedical Optics and Imaging - Proceedings of SPIE, 6440 ,

Karunakaran C.;Burgess M.;Holland C.;Mast T. 07-21-2009. Role of cavitation in bulk ultrasound ablation: A histologic study AIP Conference Proceedings, 1113 , 43-47

Salgaonkar V.;Datta S.;Holland C.;Masta T. 07-21-2009. Passive imaging of cavitational acoustic emissions with ultrasound arrays AIP Conference Proceedings, 1113 , 73-77

Cheng J.;Shaw G.;Holland C. 07-01-2005. In vitro microscopic imaging of enhanced thrombolysis with 120-kHz ultrasound in a human clot model Acoustic Research Letters Online, 6 3, 25-29

Haworth K.;Salgaonkar V.;Corregan N.;Holland C.;Mast T. 06-19-2013. Spatial specificity and sensitivity of passive cavitation imaging for monitoring high-intensity focu Proceedings of Meetings on Acoustics, 19 ,

Zhou X.;Espy-Wilson C.Y.;Boyce S.;Tiede M.;Holland C.;Choe A. 06-17-2008. A magnetic resonance imaging-based articulatory and acoustic study of "retroflex" and "bunched" Amer Journal of the Acoustical Society of America, 123 6, 4466-4481

Laing S.;Moody M.;Smulevitz B.;Kim H.;Kee P.;Huang S.;Holland C.;McPherson D. 06-01-2011. Ultrasound-enhanced thrombolytic effect of tissue plasminogen activator-loaded echogenic liposomes i Arteriosclerosis, Thrombosis, and Vascular Biology, 31 6, 1357-1359

Laing S.;Kim H.;Kopechek J.;Parikh D.;Huang S.;Klegerman M.;Holland C.;McPherson D. 06-01-2010. Ultrasound-mediated delivery of echogenic immunoliposomes to porcine vascular smooth muscle cells in Journal of Liposome Research, 20 2, 160-167

McPherson D.;Holland C. 05-07-2003. Seizing the science of ultrasound: Beyond imaging and into physiology and therapeutics Journal of the American College of Cardiology, 41 9, 1628-1630

Haworth K.;Raymond J.;Radhakrishnan K.;Moody M.;Huang S.;Peng T.;Shekhar H.;Klegerman M.;Kim H.;McPherson D.;Holland C. 05-01-2016. Erratum to: "Trans-stent B-mode Ultrasound and Passive Cavitation Imaging" in Ultrasound Med Biol 20 Ultrasound in Medicine and Biology, 42 5, 1244

Holland C. 04-01-2016. ACOUSTICAL NEWS-USA Journal of the Acoustical Society of America, 139 4,

Tiukinhoy-Laing S.;Huang S.;Klegerman M.;Holland C.;McPherson D. 03-23-2007. Ultrasound-facilitated thrombolysis using tissue-plasminogen activator-loaded echogenic liposomes Thrombosis Research, 119 6, 777-784

Klegerman M.;Wassler M.;Huang S.;Zou Y.;Kim H.;Shelat H.;Holland C.;Geng Y.;McPherson D. 03-19-2010. Liposomal modular complexes for simultaneous targeted delivery of bioactive gases and therapeutics Journal of Controlled Release, 142 3, 326-331

Toepfer N.;Racadio J.;Adams J.;Babcock D.;Holland C. 03-01-2006. Aortic pseudothrombus: A sonographic artifact in the abdominal aorta Journal of Diagnostic Medical Sonography, 22 2, 131-134

Shekhar H.;Smith N.;Raymond J.;Holland C. 02-01-2018. Effect of Temperature on the Size Distribution, Shell Properties, and Stability of Definity<sup&g Ultrasound in Medicine and Biology, 44 2, 434-446

Herbst S.M.;Klegerman M.E.;Kim H.;Qi J.;Shelat H.;Wassler M.;Moody M.R.;Yang C.M.;Ge X.;Zou Y.;Kopechek J.A.;Clubb F.J.;Kraemer D.C.;Huang S.;Holland C.K.;McPherson D.D.;Geng Y.J. 02-01-2010. Delivery of stem cells to porcine arterial wall with echogenic liposomes conjugated to antibodies ag Molecular Pharmaceutics, 7 1, 3-11

Bader K.;Haworth K.;Maxwell A.;Holland C. 01-01-2018. Post Hoc Analysis of Passive Cavitation Imaging for Classification of Histotripsy-Induced Liquefacti IEEE Transactions on Medical Imaging, 37 1, 106-115

Haworth K.;Bader K.;Rich K.;Holland C.;Mast T. 01-01-2017. Quantitative frequency-domain passive cavitation imaging IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 64 1, 177-191

Mukherjee P.;Kandadai M.;Shaw G.;Holland C.;Papautsky I. 01-01-2015. Generation of drug loaded echogenic liposomes using microfluidic hydrodynamic focusing MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, , 466-468

Ferrara K.;Griffin R.;Guha C.;Holland C.;Lafon C. 01-01-2013. TU?E?144?01: Advanced Novel Technologies &amp; Therapeutic Strategies Medical Physics, 40 6, 451

Holland C.;Shaw G.;Datta S. 01-01-2010. Ultrasound-enhanced thrombolysis Therapeutic Ultrasound: Mechanisms to Applications, , 239-260

Fowlkes J.B.;Abramowicz J.S.;Church C.C.;Holland C.K.;Miller D.L.;O'Brien W.D.;Sanghvi N.T.;Stratmeyer M.E.;Zachary J.F.;Deng C.X.;Harris G.R.;Herman B.A.;Hynynen K.H.;Merritt C.R.B.;Thomenius K.E.;Bailey M.R.;Carson P.L.;Carstensen E.L.;Frizzell L.A.;Nyborg W.L.;Barnett S.B.;Duck F.A.;Edmonds P.D.;Ziskin M.C.;Abbott J.G.;Dalecki D.;Dunn F.;Greenleaf J.F.;Salvesen K.A.;Siddiqi T.A.;Averkiou M.A.;Brayman A.A.;Everbach E.C.;Wible J.H.;Wu J.;Simpson D.G. 01-01-2008. American Institute of Ultrasound in Medicine consensus report on potential bioeffects of diagnostic Journal of Ultrasound in Medicine, 27 4, 503-515

Miller D.L.;Averkiou M.A.;Brayman A.A.;Everbach E.C.;Holland C.K.;Wible J.H.;Wu J. 01-01-2008. Bioeffects considerations for diagnostic ultrasound contrast agents Journal of Ultrasound in Medicine, 27 4, 611-632

Holland C. 01-01-2007. Online review facilitates rapid publishing Ultrasound in Medicine and Biology, 33 1, 1-2

Cheng J.;Shaw G.;Holland C. 01-01-2005. In vitro microscopic imaging of enhanced thrombolysis with 120-kHz ultrasound in a human clot model Acoustic Research Letters Online, 6 1, 25-29

Holland C.;Everbach E. 01-01-2005. Guest editorial: Sono et Gravitas - The legacy of Robert Edmund Apfel Acoustic Research Letters Online, 6 3,

Taylor C.;Holland C. 01-01-2003. Kenneth J. Taylor, MD, PhD, FACP, 1939-2003, pioneer of diagnostic ultrasound imaging. Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 22 6, 663-664

Fowlkes J.;Holland C. 01-01-2000. Mechanical bioeffects from diagnostic ultrasound: AIUM consensus statements. American Institute of U Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 19 2, 69-72

Fowlkes J.;Holland C.;Kremkau F. 01-01-2000. Mechanical bioeffects from diagnostic ultrasound: AIUM consensus statements Journal of Ultrasound in Medicine, 19 2, 68-168

Deng C.;Xu Q.;Apfel R.;Holland C. 01-01-1996. Inertial cavitation produced by pulsed ultrasound in controlled host media Journal of the Acoustical Society of America, 100 2 I, 1199-1208

Deng C.;Xu Q.;Apfel R.;Holland C. 01-01-1996. In vitro measurements of inertial cavitation thresholds in human blood Ultrasound in Medicine and Biology, 22 7, 939-948

Brown J.M.;Hammers L.W.;Barton J.W.;Holland C.K.;Scoutt L.M.;Pellerito J.S.;Taylor K.J.W. 01-01-1995. Quantitative Doppler assessment of acute scrotal inflammation Radiology, 197 2, 427-431

McCauley T.R.;Pena C.S.;Holland C.K.;Price T.B.;Gore J.C. 01-01-1995. Validation of volume flow measurements with cine phase?contrast MR imaging for peripheral arterial w Journal of Magnetic Resonance Imaging, 5 6, 663-668

Reinhold C.;Hammers L.;Taylor C.;Quedens-Case C.;Holland C.;Taylor K. 01-01-1995. Characterization of focal hepatic lesions with duplex sonography: Findings in 198 patients American Journal of Roentgenology, 164 5, 1131-1135

Dillon E.;Case C.;Ramos I.;Holland C.;Taylor K. 01-01-1993. Endovaginal pulsed and color doppler in first-trimester pregnancy Ultrasound in Medicine and Biology, 19 7, 517-525

Dillon E.;Case C.;Ramos I.;Holland C.;Taylor K. 01-01-1993. Endovaginal US and Doppler findings after first-trimester abortion Radiology, 186 1, 87-91

Holland C.;Taylor K. 01-01-1993. Blood flow quantitation: waveform analysis, volume measurement, tumor flow, and the role of color im Clinics in diagnostic ultrasound, 28 , 125-139

Crum L.;Roy R.;Dinno M.;Church C.;Apfel R.;Holland C.;Madanshetty S. 01-01-1992. Acoustic cavitation produced by microsecond pulses of ultrasound: A discussion of some selected resu Journal of the Acoustical Society of America, 91 2, 1113-1119

Holland C.;Roy R.;Apfel R.;Crum L. 01-01-1992. In Vitro Detection of Cavitation Induced by a Diagnostic Ultrasound System IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 39 1, 95-101

Apfel R.;Holland C. 01-01-1991. Gauging the likelihood of cavitation from short-pulse, low-duty cycle diagnostic ultrasound Ultrasound in Medicine and Biology, 17 2, 179-185

Holland C.;Apfel R. 01-01-1990. Thresholds for transient cavitation produced by pulsed ultrasound in a controlled nuclei environment Journal of the Acoustical Society of America, 88 5, 2059-2069

Holland C. 01-01-1989. Thresholds of transient cavitation produced by pulsed ultrasound in a controlled nuclei environment Journal of the Acoustical Society of America, 86 2, 844

Holland C.;Apfel R. 01-01-1989. An Improved Theory for the Prediction of Microcavitation Thresholds IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 36 2, 204-208

Atchley A.;Frizzell L.;Apfel R.;Holland C.;Madanshetty S.;Roy R. 01-01-1988. Thresholds for cavitation produced in water by pulsed ultrasound Ultrasonics, 26 5, 280-285